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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1061808
log Bayes Factor = 135.215
Chromosome 6   position 32,136,547  (GRCh37) Explore rs1061808 on Ensembl!
Variant rs1061808 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
K51.9 Ulcerative colitis, unspecified
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E11.9 Without complications
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
J45.9 Asthma, unspecified
0.000 0.005 0.995
E20-E35 Disorders of other endocrine glands
0.000 0.007 0.993
E16.2 Hypoglycaemia, unspecified
0.000 0.008 0.992
K51 Ulcerative colitis
0.991 0.009 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.985 0.015 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.984 0.016 0.000
G37 Other demyelinating diseases of central nervous system
0.980 0.020 0.000
E14 Unspecified diabetes mellitus
0.000 0.020 0.980
E10.1 With ketoacidosis
0.000 0.021 0.979
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.023 0.977
E11.1 With ketoacidosis
0.000 0.025 0.975
E21.3 Hyperparathyroidism, unspecified
0.000 0.030 0.970
G37.9 Demyelinating disease of central nervous system, unspecified
0.970 0.030 0.000
E24 Cushing's syndrome
0.000 0.041 0.959
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.048 0.952
K51.4 Pseudopolyposis of colon
0.949 0.051 0.000
E14.3 With ophthalmic complications
0.000 0.090 0.910
E11.3 With ophthalmic complications
0.000 0.103 0.897
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.116 0.884
E03.8 Other specified hypothyroidism
0.000 0.116 0.884
E14.1 With ketoacidosis
0.000 0.121 0.879
K51.5 Mucosal proctocolitis
0.873 0.127 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.130 0.870
E16.1 Other hypoglycaemia
0.000 0.132 0.868
E13 Other specified diabetes mellitus
0.000 0.137 0.863
E11.2 With renal complications
0.000 0.143 0.857
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.145 0.855
E14.9 Without complications
0.000 0.162 0.838
G37.8 Other specified demyelinating diseases of central nervous system
0.837 0.163 0.000
E14.4 With neurological complications
0.000 0.169 0.831
E24.9 Cushing's syndrome, unspecified
0.000 0.172 0.828
E24.0 Pituitary-dependent Cushing's disease
0.000 0.176 0.824
E10.0 With coma
0.000 0.176 0.824
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.822 0.178 0.000
E27 Other disorders of adrenal gland
0.000 0.189 0.811
E10.4 With neurological complications
0.000 0.190 0.810
E23 Hypofunction and other disorders of pituitary gland
0.000 0.209 0.791
G36 Other acute disseminated demyelination
0.788 0.212 0.000
E13.9 Without complications
0.000 0.215 0.785
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.221 0.779
E07 Other disorders of thyroid
0.000 0.222 0.778
E28 Ovarian dysfunction
0.000 0.241 0.759
E10.6 With other specified complications
0.000 0.252 0.748
E14.8 With unspecified complications
0.000 0.255 0.745
E10.7 With multiple complications
0.000 0.262 0.738
E05.8 Other thyrotoxicosis
0.000 0.266 0.734
E29 Testicular dysfunction
0.000 0.269 0.731
E10.8 With unspecified complications
0.000 0.273 0.727
E27.9 Disorder of adrenal gland, unspecified
0.000 0.278 0.722
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E31 Polyglandular dysfunction
0.000 0.286 0.714
E21.2 Other hyperparathyroidism
0.000 0.286 0.714
E14.2 Withrenal complications
0.000 0.287 0.713
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.288 0.712
E32 Diseases of thymus
0.000 0.288 0.712
E30 Disorders of puberty, not elsewhere classified
0.000 0.288 0.712
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.289 0.711
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.289 0.711
K51.1 Ulcerative (chronic) ileocolitis
0.706 0.294 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.297 0.703
G37.5 Concentric sclerosis [Balo]
0.703 0.297 0.000
G37.4 Subacute necrotising myelitis
0.703 0.297 0.000
G37.2 Central pontine myelinolysis
0.703 0.297 0.000
G37.1 Central demyelination of corpus callosum
0.703 0.297 0.000
G37.0 Diffuse sclerosis
0.703 0.297 0.000
E14.7 With multiple complications
0.000 0.297 0.703
E21.4 Other specified disorders of parathyroid gland
0.000 0.300 0.700
E14.5 With peripheral circulatory complications
0.000 0.303 0.697
E03.1 Congenital hypothyroidism without goitre
0.000 0.306 0.694
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.313 0.687
E24.3 Ectopic ACTH syndrome
0.000 0.313 0.687
E24.1 Nelson's syndrome
0.000 0.313 0.687
E26 Hyperaldosteronism
0.000 0.315 0.685
E23.2 Diabetes insipidus
0.000 0.319 0.681
E11.8 With unspecified complications
0.000 0.319 0.681
E10.2 With renal complications
0.000 0.341 0.659
E23.6 Other disorders of pituitary gland
0.000 0.345 0.655
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.352 0.647
G36.0 Neuromyelitis optica [Devic]
0.647 0.353 0.000
E14.0 With coma
0.000 0.355 0.644
E24.8 Other Cushing's syndrome
0.000 0.359 0.641
K51.8 Other ulcerative colitis
0.639 0.361 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.370 0.630
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.375 0.624
E23.7 Disorder of pituitary gland, unspecified
0.000 0.378 0.622
E13.8 With unspecified complications
0.000 0.381 0.619
E13.7 With multiple complications
0.000 0.381 0.619
E13.6 With other specified complications
0.000 0.381 0.619
E13.5 With peripheral circulatory complications
0.000 0.381 0.619
E13.4 With neurological complications
0.000 0.381 0.619
E13.2 With renal complications
0.000 0.381 0.619
E13.1 With ketoacidosis
0.000 0.381 0.619
E13.0 With coma
0.000 0.381 0.619
E10.5 With peripheral circulatory complications
0.000 0.383 0.617
E40-E46 Malnutrition
0.000 0.384 0.616
E11.0 With coma
0.000 0.385 0.614
E25 Adrenogenital disorders
0.000 0.389 0.611
E27.8 Other specified disorders of adrenal gland
0.000 0.392 0.608
E28.2 Polycystic ovarian syndrome
0.000 0.406 0.594
E11.6 With other specified complications
0.000 0.409 0.591
L40.9 Psoriasis, unspecified
0.000 0.410 0.590
E27.5 Adrenomedullary hyperfunction
0.000 0.418 0.582
E27.0 Other adrenocortical overactivity
0.000 0.418 0.582
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.433 0.567
E23.1 Drug-induced hypopituitarism
0.000 0.433 0.567
G36.9 Acute disseminated demyelination, unspecified
0.565 0.435 0.000
G36.8 Other specified acute disseminated demyelination
0.565 0.435 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.565 0.435 0.000
E07.1 Dyshormogenetic goitre
0.000 0.442 0.558
E07.0 Hypersecretion of calcitonin
0.000 0.442 0.558
E13.3 With ophthalmic complications
0.000 0.444 0.555
K90 Intestinal malabsorption
0.000 0.447 0.553
E28.9 Ovarian dysfunction, unspecified
0.000 0.455 0.544
E28.8 Other ovarian dysfunction
0.000 0.455 0.544
E28.1 Androgen excess
0.000 0.455 0.544
E28.0 Oestrogen excess
0.000 0.455 0.544
E29.1 Testicular hypofunction
0.000 0.457 0.543
E28.3 Primary ovarian failure
0.000 0.458 0.542
E07.8 Other specified disorders of thyroid
0.000 0.459 0.541
L40 Psoriasis
0.000 0.462 0.538
E20 Hypoparathyroidism
0.000 0.468 0.531
E83.1 Disorders of iron metabolism
0.528 0.472 0.000
E34 Other endocrine disorders
0.000 0.472 0.527
E26.0 Primary hyperaldosteronism
0.000 0.475 0.525
E29.9 Testicular dysfunction, unspecified
0.000 0.476 0.524
E29.8 Other testicular dysfunction
0.000 0.476 0.524
E29.0 Testicular hyperfunction
0.000 0.476 0.524
E31.0 Autoimmune polyglandular failure
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.488 0.512
E31.8 Other polyglandular dysfunction
0.000 0.488 0.512
E31.1 Polyglandular hyperfunction
0.000 0.488 0.512
E30.9 Disorder of puberty, unspecified
0.000 0.489 0.510
E30.8 Other disorders of puberty
0.000 0.489 0.510
E30.1 Precocious puberty
0.000 0.489 0.510
E30.0 Delayed puberty
0.000 0.489 0.510
E32.9 Disease of thymus, unspecified
0.000 0.489 0.510
E32.8 Other diseases of thymus
0.000 0.489 0.510
E32.1 Abscess of thymus
0.000 0.489 0.510
E32.0 Persistent hyperplasia of thymus
0.000 0.489 0.510
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.489 0.510
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.489 0.510
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.489 0.510
E27.2 Addisonian crisis
0.000 0.491 0.509
E22 Hyperfunction of pituitary gland
0.000 0.495 0.505
L40.5 Arthropathic psoriasis
0.000 0.500 0.500
E06 Thyroiditis
0.000 0.501 0.499
E26.8 Other hyperaldosteronism
0.000 0.509 0.491
E26.1 Secondary hyperaldosteronism
0.000 0.509 0.491
K51.0 Ulcerative (chronic) enterocolitis
0.487 0.512 0.000
L40.0 Psoriasis vulgaris
0.000 0.514 0.486
K90.9 Intestinal malabsorption, unspecified
0.000 0.521 0.479
K51.2 Ulcerative (chronic) proctitis
0.476 0.524 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.545 0.455
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.558 0.442
E45 Retarded development following protein-energy malnutrition
0.000 0.558 0.442
E43 Unspecified severe protein-energy malnutrition
0.000 0.558 0.442
E42 Marasmic kwashiorkor
0.000 0.558 0.442
E41 Nutritional marasmus
0.000 0.558 0.442
E40 Kwashiorkor
0.000 0.558 0.442
E25.9 Adrenogenital disorder, unspecified
0.000 0.561 0.438
E25.8 Other adrenogenital disorders
0.000 0.561 0.438
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.572 0.427
E14.6 With other specified complications
0.001 0.574 0.425
E27.1 Primary adrenocortical insufficiency
0.000 0.581 0.419
E26.9 Hyperaldosteronism, unspecified
0.000 0.581 0.418
L40.3 Pustulosis palmaris et plantaris
0.000 0.586 0.414
L40.1 Generalised pustular psoriasis
0.000 0.588 0.412
K90.3 Pancreatic steatorrhoea
0.000 0.603 0.396
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.603 0.396
K90.1 Tropical sprue
0.000 0.603 0.396
E22.1 Hyperprolactinaemia
0.000 0.606 0.393
E34.8 Other specified endocrine disorders
0.000 0.612 0.388
Z93.2 Ileostomy status
0.386 0.614 0.000
L40.4 Guttate psoriasis
0.000 0.614 0.386
L40.2 Acrodermatitis continua
0.000 0.614 0.386
E11.5 With peripheral circulatory complications
0.000 0.614 0.385
E20.1 Pseudohypoparathyroidism
0.000 0.619 0.381
E20.0 Idiopathic hypoparathyroidism
0.000 0.619 0.381
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.621 0.379
E34.5 Androgen resistance syndrome
0.000 0.622 0.378
E34.4 Constitutional tall stature
0.000 0.622 0.378
E34.3 Short stature, not elsewhere classified
0.000 0.622 0.378
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.622 0.378
E34.1 Other hypersecretion of intestinal hormones
0.000 0.622 0.378
K90.8 Other intestinal malabsorption
0.000 0.633 0.367
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.638 0.362
E22.8 Other hyperfunction of pituitary gland
0.000 0.638 0.362
E06.5 Other chronic thyroiditis
0.000 0.639 0.361
E65-E68 Obesity and other hyperalimentation
0.000 0.642 0.358
E06.4 Drug-induced thyroiditis
0.000 0.642 0.358
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.642 0.358
E06.0 Acute thyroiditis
0.000 0.642 0.358
E34.0 Carcinoid syndrome
0.000 0.651 0.349
E06.1 Subacute thyroiditis
0.000 0.656 0.344
E46 Unspecified protein-energy malnutrition
0.000 0.659 0.341
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.662 0.337
E20.8 Other hypoparathyroidism
0.001 0.662 0.337
E44.1 Mild protein-energy malnutrition
0.000 0.683 0.317
E44.0 Moderate protein-energy malnutrition
0.000 0.683 0.317
D68 Other coagulation defects
0.312 0.688 0.000
L40.8 Other psoriasis
0.000 0.690 0.309
D68.9 Coagulation defect, unspecified
0.308 0.692 0.000
E06.3 Autoimmune thyroiditis
0.000 0.700 0.300
E50-E64 Other nutritional deficiencies
0.000 0.702 0.298
D68.5 Primary Thrombophilia
0.298 0.702 0.000
D68.1 Hereditary factor XI deficiency
0.295 0.705 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.292 0.708 0.000
E83 Disorders of mineral metabolism
0.287 0.713 0.000
E20.9 Hypoparathyroidism, unspecified
0.001 0.724 0.275
E83.3 Disorders of phosphorus metabolism
0.270 0.730 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.737 0.263
E06.9 Thyroiditis, unspecified
0.000 0.739 0.260
E67 Other hyperalimentation
0.000 0.743 0.257
E68 Sequelae of hyperalimentation
0.000 0.743 0.257
D68.0 Von Willebrand's disease
0.253 0.747 0.000
D68.2 Hereditary deficiency of other clotting factors
0.245 0.755 0.000
E04 Other non-toxic goitre
0.000 0.759 0.241
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.760 0.240
D68.8 Other specified coagulation defects
0.239 0.761 0.000
E21.0 Primary hyperparathyroidism
0.000 0.761 0.239
E83.9 Disorder of mineral metabolism, unspecified
0.235 0.764 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.770 0.229
D68.4 Acquired coagulation factor deficiency
0.217 0.783 0.000
I10 Essential (primary) hypertension
0.000 0.784 0.216
E51 Thiamine deficiency
0.000 0.784 0.216
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.786 0.214
E63 Other nutritional deficiencies
0.000 0.786 0.214
E50 Vitamin A deficiency
0.000 0.786 0.214
E60 Dietary zinc deficiency
0.000 0.786 0.214
E59 Dietary selenium deficiency
0.000 0.786 0.214
E54 Ascorbic acid deficiency
0.000 0.786 0.214
E52 Niacin deficiency [pellagra]
0.000 0.786 0.214
E65 Localised adiposity
0.000 0.789 0.211
E56 Other vitamin deficiencies
0.000 0.791 0.209
E83.8 Other disorders of mineral metabolism
0.206 0.794 0.000
E83.2 Disorders of zinc metabolism
0.206 0.794 0.000
E83.0 Disorders of copper metabolism
0.206 0.794 0.000
E58 Dietary calcium deficiency
0.000 0.807 0.192
E04.0 Non-toxic diffuse goitre
0.000 0.811 0.189
E67.8 Other specified hyperalimentation
0.000 0.815 0.184
E67.3 Hypervitaminosis D
0.000 0.815 0.184
E67.2 Megavitamin-B6 syndrome
0.000 0.815 0.184
E67.1 Hypercarotenaemia
0.000 0.815 0.184
E67.0 Hypervitaminosis A
0.000 0.815 0.184
E11.4 With neurological complications
0.000 0.817 0.183
D68.6 Other Thrombophilia
0.182 0.818 0.000
E53 Deficiency of other B group vitamins
0.000 0.823 0.176
E04.8 Other specified non-toxic goitre
0.000 0.827 0.173
E51.2 Wernicke's encephalopathy
0.000 0.843 0.157
E51.9 Thiamine deficiency, unspecified
0.000 0.845 0.155
E51.8 Other manifestations of thiamine deficiency
0.000 0.845 0.155
E51.1 Beriberi
0.000 0.845 0.155
E50.9 Vitamin A deficiency, unspecified
0.000 0.846 0.153
E50.8 Other manifestations of vitamin A deficiency
0.000 0.846 0.153
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.846 0.153
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.846 0.153
E50.5 Vitamin A deficiency with night blindness
0.000 0.846 0.153
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.846 0.153
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.846 0.153
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.846 0.153
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.846 0.153
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.846 0.153
E63.9 Nutritional deficiency, unspecified
0.000 0.846 0.153
E63.8 Other specified nutritional deficiencies
0.000 0.846 0.153
E63.1 Imbalance of constituents of food intake
0.000 0.846 0.153
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.846 0.153
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.846 0.153
E64.8 Sequelae of other nutritional deficiencies
0.000 0.846 0.153
E64.3 Sequelae of rickets
0.000 0.846 0.153
E64.2 Sequelae of vitamin C deficiency
0.000 0.846 0.153
E64.1 Sequelae of vitamin A deficiency
0.000 0.846 0.153
E64.0 Sequelae of protein-energy malnutrition
0.000 0.846 0.153
E61 Deficiency of other nutrient elements
0.000 0.847 0.153
E83.4 Disorders of magnesium metabolism
0.152 0.848 0.000
K50-K52 Noninfective enteritis and colitis
0.151 0.849 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.850 0.150
E56.8 Deficiency of other vitamins
0.000 0.850 0.150
E56.0 Deficiency of vitamin E
0.000 0.850 0.150
M20.1 Hallux valgus (acquired)
0.150 0.850 0.000
E23.0 Hypopituitarism
0.001 0.854 0.145
E56.1 Deficiency of vitamin K
0.000 0.854 0.145
E55 Vitamin D deficiency
0.000 0.857 0.143
J45 Asthma
0.000 0.858 0.141
M45.X9 Ankylosing spondylitis (Site unspecified)
0.139 0.861 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.871 0.129
E53.1 Pyridoxine deficiency
0.000 0.873 0.127
E53.0 Riboflavin deficiency
0.000 0.873 0.127
E04.1 Non-toxic single thyroid nodule
0.000 0.874 0.126
L40-L45 Papulosquamous disorders
0.000 0.879 0.121
E61.9 Deficiency of nutrient element, unspecified
0.000 0.890 0.110
E61.8 Deficiency of other specified nutrient elements
0.000 0.890 0.110
E61.7 Deficiency of multiple nutrient elements
0.000 0.890 0.110
E61.6 Vanadium deficiency
0.000 0.890 0.110
E61.5 Molybdenum deficiency
0.000 0.890 0.110
E61.4 Chromium deficiency
0.000 0.890 0.110
E61.3 Manganese deficiency
0.000 0.890 0.110
E61.0 Copper deficiency
0.000 0.890 0.110
E04.9 Non-toxic goitre, unspecified
0.000 0.891 0.109
E55.0 Rickets, active
0.000 0.897 0.102
J45.1 Nonallergic asthma
0.000 0.900 0.100
K50 Crohn's disease [regional enteritis]
0.097 0.903 0.000
E61.2 Magnesium deficiency
0.000 0.908 0.091
M45 Ankylosing spondylitis
0.090 0.910 0.000
K50.1 Crohn's disease of large intestine
0.090 0.910 0.000
J45.8 Mixed asthma
0.001 0.913 0.086
L44 Other papulosquamous disorders
0.000 0.913 0.087
L41 Parapsoriasis
0.000 0.913 0.087
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.913 0.087
E53.9 Vitamin B deficiency, unspecified
0.001 0.915 0.084
E61.1 Iron deficiency
0.000 0.921 0.079
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.078 0.921 0.000
L42 Pityriasis rosea
0.000 0.928 0.072
K50.8 Other Crohn's disease
0.072 0.928 0.000
I10-I15 Hypertensive diseases
0.000 0.932 0.068
M45.X2 Ankylosing spondylitis (Cervical region)
0.067 0.933 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.064 0.935 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.064 0.935 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.064 0.935 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.064 0.935 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.064 0.935 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.064 0.935 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.938 0.062
L41.8 Other parapsoriasis
0.000 0.938 0.062
L41.5 Retiform parapsoriasis
0.000 0.938 0.062
L41.4 Large plaque parapsoriasis
0.000 0.938 0.062
L41.3 Small plaque parapsoriasis
0.000 0.938 0.062
L41.2 Lymphomatoid papulosis
0.000 0.938 0.062
L41.1 Pityriasis lichenoides chronica
0.000 0.938 0.062
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.938 0.062
L44.9 Papulosquamous disorder, unspecified
0.000 0.938 0.062
L44.8 Other specified papulosquamous disorders
0.000 0.938 0.062
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.938 0.062
L44.3 Lichen ruber moniliformis
0.000 0.938 0.062
L44.2 Lichen striatus
0.000 0.938 0.062
L44.1 Lichen nitidus
0.000 0.938 0.062
L44.0 Pityriasis rubra pilaris
0.000 0.938 0.062
E83.5 Disorders of calcium metabolism
0.062 0.938 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.062 0.938 0.000
L43 Lichen planus
0.000 0.939 0.061
I15 Secondary hypertension
0.000 0.941 0.059
M95.0 Acquired deformity of nose
0.055 0.945 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.950 0.050
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.048 0.951 0.000
I15.0 Renovascular hypertension
0.000 0.954 0.046
L43.3 Subacute (active) lichen planus
0.000 0.956 0.044
L43.2 Lichenoid drug reaction
0.000 0.956 0.044
L43.1 Bullous lichen planus
0.000 0.956 0.044
L43.0 Hypertrophic lichen planus
0.000 0.956 0.044
I13 Hypertensive heart and renal disease
0.000 0.956 0.044
I15.1 Hypertension secondary to other renal disorders
0.000 0.956 0.044
E66 Obesity
0.000 0.957 0.043
I15.8 Other secondary hypertension
0.000 0.958 0.042
I15.2 Hypertension secondary to endocrine disorders
0.000 0.958 0.042
K90-K93 Other diseases of the digestive system
0.000 0.958 0.042
A04.7 Enterocolitis due to Clostridium difficile
0.040 0.960 0.000
I11 Hypertensive heart disease
0.000 0.961 0.038
L43.8 Other lichen planus
0.000 0.963 0.037
I12 Hypertensive renal disease
0.000 0.963 0.037
D67 Hereditary factor IX deficiency
0.035 0.964 0.000
D66 Hereditary factor VIII deficiency
0.035 0.965 0.000
K50.9 Crohn's disease, unspecified
0.033 0.967 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.968 0.031
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.968 0.031
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.968 0.031
E55.9 Vitamin D deficiency, unspecified
0.000 0.969 0.031
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.000 0.969 0.031
L43.9 Lichen planus, unspecified
0.000 0.969 0.031
K50.0 Crohn's disease of small intestine
0.031 0.969 0.000
E66.1 Drug-induced obesity
0.000 0.969 0.031
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.969 0.030
Z08 Follow-up examination after treatment for malignant neoplasm
0.000 0.970 0.030
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.030 0.970 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.970 0.030
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.000 0.970 0.030
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.000 0.972 0.028
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.000 0.973 0.027
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.974 0.026
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.974 0.025
I12.9 Hypertensive renal disease without renal failure
0.000 0.975 0.025
E04.2 Non-toxic multinodular goitre
0.000 0.976 0.024
E66.0 Obesity due to excess calories
0.000 0.976 0.024
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.023 0.976 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.000 0.977 0.023
D64.9 Anaemia, unspecified
0.000 0.977 0.023
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.978 0.022
K93.1 Megacolon in Chagas' disease
0.000 0.978 0.022
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.978 0.022
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.979 0.021
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.000 0.980 0.020
E70-E90 Metabolic disorders
0.002 0.981 0.018
M95.3 Acquired deformity of neck
0.018 0.982 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.982 0.018
I12.0 Hypertensive renal disease with renal failure
0.000 0.982 0.018
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.983 0.017
K52 Other non-infective gastro-enteritis and colitis
0.017 0.983 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.017 0.983 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.017 0.983 0.000
M95.5 Acquired deformity of pelvis
0.017 0.983 0.000
M95.1 Cauliflower ear
0.017 0.983 0.000
N90.4 Leukoplakia of vulva
0.000 0.983 0.017
M95.4 Acquired deformity of chest and rib
0.016 0.983 0.000
Z83.7 Family history of diseases of the digestive system
0.000 0.984 0.016
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.984 0.015
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.985 0.015
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.985 0.015
E74 Other disorders of carbohydrate metabolism
0.001 0.986 0.013
E77 Disorders of glycoprotein metabolism
0.001 0.986 0.013
E76 Disorders of glycosaminoglycan metabolism
0.001 0.986 0.013
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.986 0.013
E70 Disorders of aromatic amino-acid metabolism
0.001 0.986 0.013
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.986 0.013
E72 Other disorders of amino-acid metabolism
0.001 0.986 0.012
N83.1 Corpus luteum cyst
0.000 0.986 0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.986 0.012
M95.2 Other acquired deformity of head
0.013 0.987 0.000
E79 Disorders of purine and pyrimidine metabolism
0.002 0.987 0.012
J45.0 Predominantly allergic asthma
0.001 0.987 0.012
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.987 0.013
E73 Lactose intolerance
0.001 0.987 0.012
K52.3 Indeterminate colitis
0.013 0.987 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.987 0.012
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.987 0.012
E89.5 Postprocedural testicular hypofunction
0.001 0.987 0.012
M95.96 Acquired deformity of musculoskeletal system, unspecified
0.012 0.987 0.000
E88 Other metabolic disorders
0.001 0.988 0.012
E84 Cystic fibrosis
0.002 0.988 0.011
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.988 0.012
R06.5 Mouth breathing
0.012 0.988 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.988 0.012
K52.0 Gastro-enteritis and colitis due to radiation
0.011 0.989 0.000
E89.1 Postprocedural hypoinsulinaemia
0.001 0.989 0.011
E89.4 Postprocedural ovarian failure
0.001 0.989 0.011
K58 Irritable bowel syndrome
0.000 0.989 0.011
E89.2 Postprocedural hypoparathyroidism
0.000 0.989 0.010
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.011 0.989 0.000
K52.1 Toxic gastro-enteritis and colitis
0.011 0.989 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.000 0.989 0.011
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.989 0.010
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.989 0.010
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.989 0.010
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.989 0.010
E74.2 Disorders of galactose metabolism
0.001 0.989 0.010
E74.1 Disorders of fructose metabolism
0.001 0.989 0.010
E74.0 Glycogen storage disease
0.001 0.989 0.010
E85 Amyloidosis
0.001 0.989 0.009
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.990 0.009
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.990 0.009
E70.3 Albinism
0.001 0.990 0.009
E70.2 Disorders of tyrosine metabolism
0.001 0.990 0.009
E70.1 Other hyperphenylalaninaemias
0.001 0.990 0.009
E70.0 Classical phenylketonuria
0.001 0.990 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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