TreeWAS – Variant ID: rs10741243

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z09.2 Follow-up examination after chemotherapy for other conditions	0.014	0.986	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.014	0.986	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.012	0.988	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.010	0.990	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.009	0.991	0.000
Z09.3 Follow-up examination after psychotherapy	0.009	0.991	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.008	0.991	0.000
Z09.4 Follow-up examination after treatment of fracture	0.008	0.992	0.000
G40 Epilepsy	0.008	0.992	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.008	0.992	0.000
J98.1 Pulmonary collapse	0.000	0.993	0.007
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.007	0.993	0.000
N30.2 Other chronic cystitis	0.000	0.993	0.007
Z09.1 Follow-up examination after radiotherapy for other conditions	0.007	0.993	0.000
C18.9 Colon, unspecified	0.000	0.993	0.007
K04.8 Radicular cyst	0.000	0.994	0.006
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.006	0.994	0.000
N30.9 Cystitis, unspecified	0.000	0.994	0.006
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.006	0.994	0.000
G40.5 Special epileptic syndromes	0.006	0.994	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.006	0.994	0.000
G40.8 Other epilepsy	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
N30 Cystitis	0.000	0.995	0.005
N30.4 Irradiation cystitis	0.000	0.995	0.005
C18 Malignant neoplasm of colon	0.000	0.995	0.005
D86 Sarcoidosis	0.005	0.995	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.005	0.995	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D80-D89 Certain disorders involving the immune mechanism	0.005	0.995	0.000
K14.8 Other diseases of tongue	0.005	0.995	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
C18.0 Caecum	0.000	0.995	0.005
C18.3 Hepatic flexure	0.000	0.995	0.005
C18.7 Sigmoid colon	0.000	0.995	0.005
D63.8 Anaemia in other chronic diseases classified elsewhere	0.005	0.995	0.000
K04.7 Periapical abscess without sinus	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.004	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.004
C18.2 Ascending colon	0.000	0.996	0.004
D70 Agranulocytosis	0.004	0.996	0.000
C18.1 Appendix	0.000	0.996	0.004
K04 Diseases of pulp and periapical tissues	0.000	0.996	0.004
D70-D77 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
N30.0 Acute cystitis	0.000	0.996	0.004
C18.6 Descending colon	0.000	0.996	0.004
J98 Other respiratory disorders	0.000	0.996	0.004
D69.3 Idiopathic thrombocytopenic purpura	0.004	0.996	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
N30.8 Other cystitis	0.000	0.996	0.004
D82 Immunodeficiency associated with other major defects	0.004	0.996	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D83 Common variable immunodeficiency	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
C18.4 Transverse colon	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.000	0.996	0.004
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
T42.4 Benzodiazepines	0.000	0.996	0.004
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
C18.8 Overlapping lesion of colon	0.000	0.996	0.004
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.996	0.004
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
D84 Other immunodeficiencies	0.003	0.996	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.996	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.003
D63 Anaemia in chronic diseases classified elsewhere	0.003	0.996	0.000
D68 Other coagulation defects	0.004	0.996	0.000
J98.6 Disorders of diaphragm	0.000	0.996	0.003
D80 Immunodeficiency with predominantly antibody defects	0.003	0.996	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.997	0.003
J98.4 Other disorders of lung	0.000	0.997	0.003
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.003	0.997	0.000
K04.3 Abnormal hard tissue formation in pulp	0.000	0.997	0.003
K04.2 Pulp degeneration	0.000	0.997	0.003
K04.1 Necrosis of pulp	0.000	0.997	0.003
C18.5 Splenic flexure	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
D74 Methaemoglobinaemia	0.003	0.997	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.997	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.997	0.000
S22.3 Fracture of rib	0.000	0.997	0.003
D73 Diseases of spleen	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
D82.1 Di George's syndrome	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.003	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
J98.3 Compensatory emphysema	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
K04.0 Pulpitis	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.003	0.997	0.000
D69.0 Allergic purpura	0.003	0.997	0.000
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
D81.9 Combined immunodeficiency, unspecified	0.003	0.997	0.000
D81.8 Other combined immunodeficiencies	0.003	0.997	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.997	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.997	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.997	0.000
D81.4 Nezelof's syndrome	0.003	0.997	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.997	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.997	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.997	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
J98.2 Interstitial emphysema	0.000	0.997	0.003
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.003	0.997	0.000
J98.8 Other specified respiratory disorders	0.000	0.997	0.003
D72 Other disorders of white blood cells	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.997	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
S27 Injury of other and unspecified intrathoracic organs	0.000	0.997	0.003
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
D73.9 Disease of spleen, unspecified	0.003	0.997	0.000
D76.3 Other histiocytosis syndromes	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
D73.4 Cyst of spleen	0.003	0.997	0.000
S27.1 Traumatic haemothorax	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.003	0.997	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.003	0.997	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.003	0.997	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.003	0.997	0.000
N30.3 Trigonitis	0.000	0.997	0.003
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
S27.0 Traumatic pneumothorax	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.002	0.997	0.000
D74.8 Other methaemoglobinaemias	0.002	0.997	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.997	0.003
S22.31 Fracture of rib (open)	0.000	0.997	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
D73.2 Chronic congestive splenomegaly	0.002	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
D73.5 Infarction of spleen	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.997	0.000
H54.4 Blindness, one eye	0.003	0.997	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.997	0.000
T42.0 Hydantoin derivatives	0.000	0.997	0.002
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
D73.1 Hypersplenism	0.002	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.997	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.002
D55-D59 Haemolytic anaemias	0.002	0.997	0.000
D68.9 Coagulation defect, unspecified	0.002	0.997	0.000
R10.1 Pain localised to upper abdomen	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.002
D73.3 Abscess of spleen	0.002	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.002
D84.8 Other specified immunodeficiencies	0.002	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.997	0.002
T42.1 Iminostilbenes	0.000	0.997	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.002
T46.7 Peripheral vasodilators	0.000	0.997	0.002
O32.1 Maternal care for breech presentation	0.003	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.997	0.002
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
S22.5 Flail chest	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.002
S27.9 Injury of unspecified intrathoracic organ	0.000	0.998	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.998	0.002
S27.6 Injury of pleura	0.000	0.998	0.002
S27.5 Injury of thoracic trachea	0.000	0.998	0.002
S27.4 Injury of bronchus	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
H18 Other disorders of cornea	0.002	0.998	0.000
G40.9 Epilepsy, unspecified	0.002	0.998	0.000
N18.9 Chronic renal failure, unspecified	0.002	0.998	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
S20-S29 Injuries to the thorax	0.000	0.998	0.002
S27.3 Other injuries of lung	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
D33.3 Cranial nerves	0.000	0.998	0.002
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.998	0.002
D72.1 Eosinophilia	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
M65.34 Trigger finger-Hand	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
J95-J99 Other diseases of the respiratory system	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D61 Other aplastic anaemias	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
D56 Thalassaemia	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
S22.51 Flail chest (open)	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
H18.7 Other corneal deformities	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
S21 Open wound of thorax	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.002
H18.2 Other corneal oedema	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
H18.4 Corneal degeneration	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.998	0.002
S26 Injury of heart	0.000	0.998	0.002
S25 Injury of blood vessels of thorax	0.000	0.998	0.002
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.000	0.998	0.002
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
S24 Injury of nerves and spinal cord at thorax level	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
T45.4 Iron and its compounds	0.000	0.998	0.001
Z63.7 Other stressful life events affecting family and household	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.998	0.002
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.998	0.002
S20 Superficial injury of thorax	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.998	0.002
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.001	0.998	0.000
D57.3 Sickle-cell trait	0.001	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.998	0.000
D58.1 Hereditary elliptocytosis	0.001	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
R52.1 Chronic intractable pain	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.002
C45 Mesothelioma	0.000	0.998	0.002
H54 Blindness and low vision	0.002	0.998	0.000
J96 Respiratory failure, not elsewhere classified	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.001	0.998	0.000
D56.8 Other thalassaemias	0.001	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.998	0.000
D56.2 Delta-beta thalassaemia	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations