TreeWAS – Variant ID: rs10755644

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.686	0.314
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.739	0.261
K90.3 Pancreatic steatorrhoea	0.000	0.775	0.225
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.775	0.225
K90.1 Tropical sprue	0.000	0.775	0.225
K90.8 Other intestinal malabsorption	0.000	0.785	0.214
E10.9 Without complications	0.000	0.867	0.133
E10 Insulin-dependent diabetes mellitus	0.000	0.867	0.133
E10.4 With neurological complications	0.000	0.878	0.122
E10.5 With peripheral circulatory complications	0.000	0.879	0.121
E10.6 With other specified complications	0.000	0.880	0.120
E10.8 With unspecified complications	0.000	0.889	0.111
E10.2 With renal complications	0.000	0.903	0.097
E10.7 With multiple complications	0.000	0.904	0.096
E10.1 With ketoacidosis	0.000	0.905	0.095
K90.9 Intestinal malabsorption, unspecified	0.001	0.906	0.094
E10.0 With coma	0.000	0.911	0.089
E83 Disorders of mineral metabolism	0.000	0.914	0.086
E10.3 With ophthalmic complications	0.000	0.916	0.084
E10-E14 Diabetes mellitus	0.000	0.929	0.071
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.938	0.062
E83.8 Other disorders of mineral metabolism	0.000	0.938	0.062
E83.2 Disorders of zinc metabolism	0.000	0.938	0.062
E83.0 Disorders of copper metabolism	0.000	0.938	0.062
E13 Other specified diabetes mellitus	0.000	0.940	0.060
E14 Unspecified diabetes mellitus	0.000	0.945	0.055
E13.9 Without complications	0.000	0.947	0.053
E14.3 With ophthalmic complications	0.000	0.948	0.052
E12 Malnutrition-related diabetes mellitus	0.000	0.949	0.051
E13.8 With unspecified complications	0.000	0.956	0.043
E13.7 With multiple complications	0.000	0.956	0.043
E13.6 With other specified complications	0.000	0.956	0.043
E13.5 With peripheral circulatory complications	0.000	0.956	0.043
E13.4 With neurological complications	0.000	0.956	0.043
E13.2 With renal complications	0.000	0.956	0.043
E13.1 With ketoacidosis	0.000	0.956	0.043
E13.0 With coma	0.000	0.956	0.043
E13.3 With ophthalmic complications	0.000	0.958	0.042
E14.5 With peripheral circulatory complications	0.000	0.959	0.041
E14.4 With neurological complications	0.000	0.960	0.040
E14.7 With multiple complications	0.000	0.961	0.039
E14.6 With other specified complications	0.000	0.961	0.039
E14.2 Withrenal complications	0.000	0.961	0.039
E14.0 With coma	0.000	0.961	0.039
E12.9 Without complications	0.000	0.963	0.037
E12.8 With unspecified complications	0.000	0.963	0.037
E12.7 With multiple complications	0.000	0.963	0.037
E12.6 With other specified complications	0.000	0.963	0.037
E12.5 With peripheral circulatory complications	0.000	0.963	0.037
E12.4 With neurological complications	0.000	0.963	0.037
E12.3 With ophthalmic complications	0.000	0.963	0.037
E12.2 With renal complications	0.000	0.963	0.037
E12.1 With ketoacidosis	0.000	0.963	0.037
E12.0 With coma	0.000	0.963	0.037
E83.4 Disorders of magnesium metabolism	0.000	0.965	0.035
E83.3 Disorders of phosphorus metabolism	0.000	0.966	0.034
E14.8 With unspecified complications	0.000	0.966	0.034
E14.1 With ketoacidosis	0.000	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.969	0.031
E70-E90 Metabolic disorders	0.000	0.970	0.030
E88 Other metabolic disorders	0.000	0.973	0.027
E11 Non-insulin-dependent diabetes mellitus	0.000	0.974	0.026
E40-E46 Malnutrition	0.000	0.975	0.025
E85 Amyloidosis	0.000	0.976	0.024
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.976	0.024
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.978	0.022
E83.5 Disorders of calcium metabolism	0.000	0.978	0.022
E84 Cystic fibrosis	0.000	0.978	0.022
E77 Disorders of glycoprotein metabolism	0.000	0.978	0.022
E76 Disorders of glycosaminoglycan metabolism	0.000	0.978	0.022
E72 Other disorders of amino-acid metabolism	0.000	0.978	0.022
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.978	0.022
E70 Disorders of aromatic amino-acid metabolism	0.000	0.978	0.022
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.978	0.022
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.978	0.022
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.978	0.022
E11.5 With peripheral circulatory complications	0.000	0.979	0.021
E46 Unspecified protein-energy malnutrition	0.000	0.979	0.021
E88.8 Other specified metabolic disorders	0.000	0.979	0.021
E65-E68 Obesity and other hyperalimentation	0.000	0.979	0.021
E14.9 Without complications	0.000	0.979	0.021
E88.2 Lipomatosis, not elsewhere classified	0.000	0.979	0.021
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.980	0.020
E85.9 Amyloidosis, unspecified	0.000	0.980	0.020
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.980	0.020
E79 Disorders of purine and pyrimidine metabolism	0.000	0.980	0.020
K90-K93 Other diseases of the digestive system	0.000	0.980	0.020
E11.8 With unspecified complications	0.000	0.980	0.020
E11.0 With coma	0.000	0.981	0.019
E16 Other disorders of pancreatic internal secretion	0.000	0.981	0.019
E88.3 Tumour lysis syndrome	0.000	0.981	0.019
E11.7 With multiple complications	0.000	0.981	0.019
E11.1 With ketoacidosis	0.000	0.982	0.018
E11.2 With renal complications	0.000	0.982	0.018
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.982	0.018
E45 Retarded development following protein-energy malnutrition	0.000	0.982	0.018
E43 Unspecified severe protein-energy malnutrition	0.000	0.982	0.018
E42 Marasmic kwashiorkor	0.000	0.982	0.018
E41 Nutritional marasmus	0.000	0.982	0.018
E40 Kwashiorkor	0.000	0.982	0.018
E85.4 Organ-limited amyloidosis	0.000	0.982	0.018
E89.2 Postprocedural hypoparathyroidism	0.000	0.982	0.018
E88.9 Metabolic disorder, unspecified	0.000	0.982	0.018
E65 Localised adiposity	0.000	0.982	0.018
E85.8 Other amyloidosis	0.000	0.982	0.017
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.982	0.017
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.982	0.017
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.982	0.017
E15 Nondiabetic hypoglycaemic coma	0.000	0.982	0.017
E16.2 Hypoglycaemia, unspecified	0.000	0.982	0.018
E74 Other disorders of carbohydrate metabolism	0.000	0.983	0.017
E11.6 With other specified complications	0.000	0.983	0.017
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.983	0.017
E11.4 With neurological complications	0.000	0.983	0.017
E75.5 Other lipid storage disorders	0.000	0.983	0.017
E89.4 Postprocedural ovarian failure	0.000	0.983	0.017
E75.6 Lipid storage disorder, unspecified	0.000	0.984	0.016
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.984	0.016
E75.3 Sphingolipidosis, unspecified	0.000	0.984	0.016
E75.2 Other sphingolipidosis	0.000	0.984	0.016
E75.1 Other gangliosidosis	0.000	0.984	0.016
E75.0 GM2 gangliosidosis	0.000	0.984	0.016
E73 Lactose intolerance	0.000	0.984	0.016
E85.3 Secondary systemic amyloidosis	0.000	0.984	0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.984	0.016
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.984	0.016
E70.3 Albinism	0.000	0.984	0.016
E70.2 Disorders of tyrosine metabolism	0.000	0.984	0.016
E70.1 Other hyperphenylalaninaemias	0.000	0.984	0.016
E70.0 Classical phenylketonuria	0.000	0.984	0.016
E71.3 Disorders of fatty-acid metabolism	0.000	0.984	0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.984	0.016
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.984	0.016
E71.0 Maple-syrup-urine disease	0.000	0.984	0.016
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.984	0.016
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.984	0.016
E72.5 Disorders of glycine metabolism	0.000	0.984	0.016
E72.4 Disorders of ornithine metabolism	0.000	0.984	0.016
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.984	0.016
E72.2 Disorders of urea cycle metabolism	0.000	0.984	0.016
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.984	0.016
E72.0 Disorders of amino-acid transport	0.000	0.984	0.016
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.984	0.016
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.984	0.016
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.984	0.016
E76.2 Other mucopolysaccharidoses	0.000	0.984	0.016
E76.1 Mucopolysaccharidosis, type II	0.000	0.984	0.016
E76.0 Mucopolysaccharidosis, type I	0.000	0.984	0.016
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.984	0.016
E77.8 Other disorders of glycoprotein metabolism	0.000	0.984	0.016
E77.1 Defects in glycoprotein degradation	0.000	0.984	0.016
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.984	0.016
E84.9 Cystic fibrosis, unspecified	0.000	0.984	0.016
E84.8 Cystic fibrosis with other manifestations	0.000	0.984	0.016
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.984	0.016
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.984	0.016
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.984	0.016
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.984	0.016
E89.5 Postprocedural testicular hypofunction	0.000	0.984	0.016
E89.1 Postprocedural hypoinsulinaemia	0.000	0.984	0.016
E89.0 Postprocedural hypothyroidism	0.000	0.984	0.016
E67 Other hyperalimentation	0.000	0.985	0.015
E68 Sequelae of hyperalimentation	0.000	0.985	0.015
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.985	0.015
E80.5 Crigler-Najjar syndrome	0.000	0.985	0.015
E80.3 Defects of catalase and peroxydase	0.000	0.985	0.015
E80.1 Porphyria cutanea tarda	0.000	0.985	0.015
E80.0 Hereditary erythropoietic porphyria	0.000	0.985	0.015
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.985	0.014
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.985	0.014
E79.1 Lesch-Nyhan syndrome	0.000	0.985	0.014
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.985	0.014
G44.2 Tension-type headache	0.015	0.985	0.000
E80.4 Gilbert's syndrome	0.000	0.986	0.014
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.986	0.014
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.986	0.014
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.986	0.014
E16.4 Abnormal secretion of gastrin	0.000	0.986	0.014
E16.3 Increased secretion of glucagon	0.000	0.986	0.014
E80.2 Other porphyria	0.000	0.986	0.014
E80.6 Other disorders of bilirubin metabolism	0.000	0.986	0.014
E44.1 Mild protein-energy malnutrition	0.000	0.987	0.013
E44.0 Moderate protein-energy malnutrition	0.000	0.987	0.013
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.987	0.012
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.987	0.012
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.987	0.012
E74.2 Disorders of galactose metabolism	0.000	0.987	0.012
E74.1 Disorders of fructose metabolism	0.000	0.987	0.012
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.988	0.012
E11.3 With ophthalmic complications	0.000	0.988	0.012
E73.8 Other lactose intolerance	0.000	0.988	0.012
E73.1 Secondary lactase deficiency	0.000	0.988	0.012
E73.0 Congenital lactase deficiency	0.000	0.988	0.012
E00-E07 Disorders of thyroid gland	0.000	0.988	0.012
E74.0 Glycogen storage disease	0.000	0.988	0.011
E50-E64 Other nutritional deficiencies	0.000	0.988	0.011
E67.8 Other specified hyperalimentation	0.000	0.989	0.011
E67.3 Hypervitaminosis D	0.000	0.989	0.011
E67.2 Megavitamin-B6 syndrome	0.000	0.989	0.011
E67.1 Hypercarotenaemia	0.000	0.989	0.011
E67.0 Hypervitaminosis A	0.000	0.989	0.011
C71.9 Brain, unspecified	0.011	0.989	0.000
C71.2 Temporal lobe	0.011	0.989	0.000
C71 Malignant neoplasm of brain	0.011	0.989	0.000
M41.9 Scoliosis, unspecified	0.011	0.989	0.000
E16.1 Other hypoglycaemia	0.000	0.989	0.010
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.010
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.010
E20-E35 Disorders of other endocrine glands	0.000	0.990	0.010
M41.96 Scoliosis, unspecified (Lumbar region)	0.010	0.990	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.010	0.990	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.010	0.990	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.010	0.990	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.990	0.010
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.990	0.010
C71.1 Frontal lobe	0.010	0.990	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.990	0.009
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.991	0.009
C71.3 Parietal lobe	0.009	0.991	0.000
E07 Other disorders of thyroid	0.000	0.991	0.009
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.991	0.009
E00 Congenital iodine-deficiency syndrome	0.000	0.991	0.009
E06 Thyroiditis	0.000	0.991	0.009
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.991	0.008
E63 Other nutritional deficiencies	0.000	0.991	0.008
E56 Other vitamin deficiencies	0.000	0.991	0.008
E50 Vitamin A deficiency	0.000	0.991	0.008
E60 Dietary zinc deficiency	0.000	0.991	0.008
E59 Dietary selenium deficiency	0.000	0.991	0.008
E54 Ascorbic acid deficiency	0.000	0.991	0.008
E52 Niacin deficiency [pellagra]	0.000	0.991	0.008
E66 Obesity	0.000	0.991	0.009
E04 Other non-toxic goitre	0.000	0.991	0.009
C71.7 Brain stem	0.008	0.992	0.000
E58 Dietary calcium deficiency	0.000	0.992	0.008
E28 Ovarian dysfunction	0.000	0.992	0.008
C71.0 Cerebrum, except lobes and ventricles	0.008	0.992	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.008	0.992	0.000
C71.6 Cerebellum	0.008	0.992	0.000
C71.5 Cerebral ventricle	0.008	0.992	0.000
E20 Hypoparathyroidism	0.000	0.992	0.008
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.008	0.992	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.008	0.992	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.008	0.992	0.000
E23.2 Diabetes insipidus	0.000	0.992	0.008
E53 Deficiency of other B group vitamins	0.000	0.992	0.008
E51 Thiamine deficiency	0.000	0.992	0.008
E26 Hyperaldosteronism	0.000	0.992	0.008
E23 Hypofunction and other disorders of pituitary gland	0.000	0.992	0.008
E28.2 Polycystic ovarian syndrome	0.000	0.992	0.008
E03 Other hypothyroidism	0.000	0.992	0.008
E29 Testicular dysfunction	0.000	0.992	0.008
C71.8 Overlapping lesion of brain	0.008	0.992	0.000
E78.4 Other hyperlipidaemia	0.000	0.992	0.008
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.992	0.008
E32 Diseases of thymus	0.000	0.992	0.008
E31 Polyglandular dysfunction	0.000	0.992	0.008
E30 Disorders of puberty, not elsewhere classified	0.000	0.992	0.008
E25 Adrenogenital disorders	0.000	0.992	0.008
E03.8 Other specified hypothyroidism	0.000	0.992	0.008
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.992	0.008
E34 Other endocrine disorders	0.000	0.993	0.007
E07.9 Disorder of thyroid, unspecified	0.000	0.993	0.007
E55 Vitamin D deficiency	0.000	0.993	0.007
E78.6 Lipoprotein deficiency	0.000	0.993	0.007
R31 Unspecified haematuria	0.007	0.993	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.993	0.007
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.007	0.993	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.993	0.007
E78.3 Hyperchylomicronaemia	0.000	0.993	0.007
E24 Cushing's syndrome	0.000	0.993	0.007
G44 Other headache syndromes	0.007	0.993	0.000
E06.3 Autoimmune thyroiditis	0.000	0.993	0.007
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.993	0.006
E07.1 Dyshormogenetic goitre	0.000	0.993	0.007
E07.0 Hypersecretion of calcitonin	0.000	0.993	0.007
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.993	0.006
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.993	0.006
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.993	0.006
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.993	0.006
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.993	0.006
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.993	0.006
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.993	0.006
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.993	0.006
E04.0 Non-toxic diffuse goitre	0.000	0.993	0.006
E78.1 Pure hyperglyceridaemia	0.000	0.993	0.006
E06.5 Other chronic thyroiditis	0.000	0.994	0.006
E06.4 Drug-induced thyroiditis	0.000	0.994	0.006
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.994	0.006
E06.1 Subacute thyroiditis	0.000	0.994	0.006
E06.0 Acute thyroiditis	0.000	0.994	0.006
E50.9 Vitamin A deficiency, unspecified	0.000	0.994	0.006
E50.8 Other manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.994	0.006
E50.5 Vitamin A deficiency with night blindness	0.000	0.994	0.006
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.994	0.006
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.994	0.006
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.994	0.006
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.994	0.006
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.994	0.006
E56.9 Vitamin deficiency, unspecified	0.000	0.994	0.006
E56.8 Deficiency of other vitamins	0.000	0.994	0.006
E56.1 Deficiency of vitamin K	0.000	0.994	0.006
E56.0 Deficiency of vitamin E	0.000	0.994	0.006
E63.9 Nutritional deficiency, unspecified	0.000	0.994	0.006
E63.8 Other specified nutritional deficiencies	0.000	0.994	0.006
E63.1 Imbalance of constituents of food intake	0.000	0.994	0.006
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.994	0.006
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.994	0.006
E64.8 Sequelae of other nutritional deficiencies	0.000	0.994	0.006
E64.3 Sequelae of rickets	0.000	0.994	0.006
E64.2 Sequelae of vitamin C deficiency	0.000	0.994	0.006
E64.1 Sequelae of vitamin A deficiency	0.000	0.994	0.006
E64.0 Sequelae of protein-energy malnutrition	0.000	0.994	0.006
E66.1 Drug-induced obesity	0.000	0.994	0.006
E04.8 Other specified non-toxic goitre	0.000	0.994	0.006
E20.9 Hypoparathyroidism, unspecified	0.000	0.994	0.006
C71.4 Occipital lobe	0.006	0.994	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.994	0.006
M79.10 Myalgia (Multiple sites)	0.006	0.994	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.994	0.006
E28.8 Other ovarian dysfunction	0.000	0.994	0.006
E28.1 Androgen excess	0.000	0.994	0.006
E28.0 Oestrogen excess	0.000	0.994	0.006
E73.9 Lactose intolerance, unspecified	0.001	0.994	0.005
G44.8 Other specified headache syndromes	0.006	0.994	0.000
M22.2 Patellofemoral disorders	0.006	0.994	0.000
E26.0 Primary hyperaldosteronism	0.000	0.994	0.006
E20.8 Other hypoparathyroidism	0.000	0.994	0.006
E20.1 Pseudohypoparathyroidism	0.000	0.994	0.006
E20.0 Idiopathic hypoparathyroidism	0.000	0.994	0.006
E66.0 Obesity due to excess calories	0.000	0.994	0.006
G31.0 Circumscribed brain atrophy	0.000	0.994	0.006
E24.2 Drug-induced Cushing's syndrome	0.000	0.994	0.006
E78.2 Mixed hyperlipidaemia	0.000	0.994	0.006
E04.2 Non-toxic multinodular goitre	0.000	0.994	0.006
E53.1 Pyridoxine deficiency	0.000	0.994	0.006
E53.0 Riboflavin deficiency	0.000	0.994	0.006
E51.9 Thiamine deficiency, unspecified	0.000	0.994	0.006
E51.8 Other manifestations of thiamine deficiency	0.000	0.994	0.006
E51.1 Beriberi	0.000	0.994	0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.994	0.006
E23.1 Drug-induced hypopituitarism	0.000	0.994	0.006
E26.9 Hyperaldosteronism, unspecified	0.000	0.994	0.006
E26.8 Other hyperaldosteronism	0.000	0.994	0.006
E26.1 Secondary hyperaldosteronism	0.000	0.994	0.006
E29.1 Testicular hypofunction	0.000	0.994	0.006
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.006	0.994	0.000
E03.5 Myxoedema coma	0.000	0.994	0.006
E03.4 Atrophy of thyroid (acquired)	0.000	0.994	0.006
E03.3 Postinfectious hypothyroidism	0.000	0.994	0.006
E03.1 Congenital hypothyroidism without goitre	0.000	0.994	0.006
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.994	0.006
E29.9 Testicular dysfunction, unspecified	0.000	0.994	0.006
E29.8 Other testicular dysfunction	0.000	0.994	0.006
E29.0 Testicular hyperfunction	0.000	0.994	0.006
E27 Other disorders of adrenal gland	0.000	0.994	0.006
E53.9 Vitamin B deficiency, unspecified	0.000	0.994	0.006
E25.9 Adrenogenital disorder, unspecified	0.000	0.994	0.006
E25.8 Other adrenogenital disorders	0.000	0.994	0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.994	0.006
E30.9 Disorder of puberty, unspecified	0.000	0.994	0.006
E30.8 Other disorders of puberty	0.000	0.994	0.006
E30.1 Precocious puberty	0.000	0.994	0.006
E30.0 Delayed puberty	0.000	0.994	0.006
E31.9 Polyglandular dysfunction, unspecified	0.000	0.994	0.006
E31.8 Other polyglandular dysfunction	0.000	0.994	0.006
E31.1 Polyglandular hyperfunction	0.000	0.994	0.006
E31.0 Autoimmune polyglandular failure	0.000	0.994	0.006
E32.9 Disease of thymus, unspecified	0.000	0.994	0.006
E32.8 Other diseases of thymus	0.000	0.994	0.006
E32.1 Abscess of thymus	0.000	0.994	0.006
E32.0 Persistent hyperplasia of thymus	0.000	0.994	0.006
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.994	0.006
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.994	0.006
E06.9 Thyroiditis, unspecified	0.000	0.994	0.006
E34.8 Other specified endocrine disorders	0.000	0.994	0.006
E07.8 Other specified disorders of thyroid	0.000	0.994	0.006
E27.1 Primary adrenocortical insufficiency	0.000	0.994	0.006
E23.7 Disorder of pituitary gland, unspecified	0.000	0.994	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.994	0.006
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.994	0.006
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.006	0.994	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.994	0.005
E34.5 Androgen resistance syndrome	0.000	0.994	0.005
E34.4 Constitutional tall stature	0.000	0.994	0.005
E34.3 Short stature, not elsewhere classified	0.000	0.994	0.005
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.994	0.005
E34.1 Other hypersecretion of intestinal hormones	0.000	0.994	0.005
M41 Scoliosis	0.006	0.994	0.000
E55.0 Rickets, active	0.000	0.994	0.005
E53.8 Deficiency of other specified B group vitamins	0.000	0.995	0.005
E51.2 Wernicke's encephalopathy	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.000	0.995	0.005
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.995	0.005
E24.3 Ectopic ACTH syndrome	0.000	0.995	0.005
E24.1 Nelson's syndrome	0.000	0.995	0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.995	0.005
G44.1 Vascular headache, not elsewhere classified	0.005	0.995	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.000	0.995	0.005
G44.3 Chronic posttraumatic headache	0.005	0.995	0.000
E61 Deficiency of other nutrient elements	0.001	0.995	0.004
E34.0 Carcinoid syndrome	0.000	0.995	0.005
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.995	0.005
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.995	0.005
E24.0 Pituitary-dependent Cushing's disease	0.000	0.995	0.004
E87.3 Alkalosis	0.000	0.995	0.005
C69 Malignant neoplasm of eye and adnexa	0.005	0.995	0.000
G44.0 Cluster headache syndrome	0.005	0.995	0.000
M79.19 Myalgia (Site unspecified)	0.005	0.995	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.995	0.005
C70 Malignant neoplasm of meninges	0.005	0.995	0.000
M22 Disorders of patella	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.004
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.995	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.004
E27.0 Other adrenocortical overactivity	0.000	0.995	0.004
N04.9 Unspecified	0.000	0.995	0.004
E28.3 Primary ovarian failure	0.000	0.996	0.004
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.004
M79.1 Myalgia	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.996	0.004
M41.5 Other secondary scoliosis	0.004	0.996	0.000
M41.4 Neuromuscular scoliosis	0.004	0.996	0.000
M41.3 Thoracogenic scoliosis	0.004	0.996	0.000
M41.2 Other idiopathic scoliosis	0.004	0.996	0.000
M41.1 Juvenile idiopathic scoliosis	0.004	0.996	0.000
M41.0 Infantile idiopathic scoliosis	0.004	0.996	0.000
M22.0 Recurrent dislocation of patella	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.996	0.004
E87.0 Hyperosmolality and hypernatraemia	0.000	0.996	0.004
M22.3 Other derangements of patella	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
E78.8 Other disorders of lipoprotein metabolism	0.000	0.996	0.004
G31.2 Degeneration of nervous system due to alcohol	0.000	0.996	0.004
K62.5 Haemorrhage of anus and rectum	0.004	0.996	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.004	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.996	0.004
E21.2 Other hyperparathyroidism	0.000	0.996	0.004
Z97.5 Presence of (intra-uterine) contraceptive device	0.004	0.996	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.996	0.004
E66.9 Obesity, unspecified	0.000	0.996	0.004
C70.0 Cerebral meninges	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.001	0.996	0.003
E61.8 Deficiency of other specified nutrient elements	0.001	0.996	0.003
E61.7 Deficiency of multiple nutrient elements	0.001	0.996	0.003
E61.6 Vanadium deficiency	0.001	0.996	0.003
E61.5 Molybdenum deficiency	0.001	0.996	0.003
E61.4 Chromium deficiency	0.001	0.996	0.003
E61.3 Manganese deficiency	0.001	0.996	0.003
E61.0 Copper deficiency	0.001	0.996	0.003
C69.9 Eye, unspecified	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
G30 Alzheimer's disease	0.000	0.996	0.004
C69.3 Choroid	0.004	0.996	0.000
M22.9 Disorder of patella, unspecified	0.004	0.996	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
M22.8 Other disorders of patella	0.004	0.996	0.000
M41.8 Other forms of scoliosis	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.996	0.004
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.996	0.004
C69.8 Overlapping lesion of eye and adnexa	0.003	0.996	0.000
C69.5 Lachrymal gland and duct	0.003	0.996	0.000
C69.4 Ciliary body	0.003	0.996	0.000
C69.2 Retina	0.003	0.996	0.000
C69.1 Cornea	0.003	0.996	0.000
C69.6 Orbit	0.003	0.996	0.000
C70.9 Meninges, unspecified	0.003	0.996	0.000
C70.1 Spinal meninges	0.003	0.996	0.000
E05.8 Other thyrotoxicosis	0.000	0.996	0.004
M22.1 Recurrent subluxation of patella	0.003	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.996	0.003
E87.2 Acidosis	0.000	0.996	0.004
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
C69.0 Conjunctiva	0.003	0.996	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.003	0.996	0.000
E05.5 Thyroid crisis or storm	0.000	0.996	0.003
E05.4 Thyrotoxicosis factitia	0.000	0.996	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.996	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.996	0.003
E27.2 Addisonian crisis	0.000	0.996	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
M79.17 Myalgia (Ankle and foot)	0.003	0.997	0.000
M79.14 Myalgia (Hand)	0.003	0.997	0.000
M79.13 Myalgia (Forearm)	0.003	0.997	0.000
M79.12 Myalgia (Upper arm)	0.003	0.997	0.000
E87.7 Fluid overload	0.000	0.997	0.003
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.003	0.997	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations