TreeWAS – Variant ID: rs10758161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K58.0 Irritable bowel syndrome with diarrhoea	0.012	0.988	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.010	0.990	0.000
K58 Irritable bowel syndrome	0.010	0.990	0.000
F10.0 Acute intoxication	0.000	0.991	0.009
I51.7 Cardiomegaly	0.008	0.992	0.000
L03.3 Cellulitis of trunk	0.007	0.993	0.000
M51.2 Other specified intervertebral disk displacement	0.007	0.993	0.000
L03.2 Cellulitis of face	0.006	0.994	0.000
N30.1 Interstitial cystitis (chronic)	0.005	0.995	0.000
L03 Cellulitis	0.005	0.995	0.000
L03.0 Cellulitis of finger and toe	0.005	0.995	0.000
N30 Cystitis	0.005	0.995	0.000
N30.9 Cystitis, unspecified	0.005	0.995	0.000
I34.0 Mitral (valve) insufficiency	0.005	0.995	0.000
N30.3 Trigonitis	0.005	0.995	0.000
N30.0 Acute cystitis	0.005	0.995	0.000
N30.8 Other cystitis	0.004	0.996	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.996	0.004
L03.8 Cellulitis of other sites	0.004	0.996	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.996	0.004
N30.2 Other chronic cystitis	0.004	0.996	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.996	0.004
Z45.0 Adjustment and management of cardiac pacemaker	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
G56.2 Lesion of ulnar nerve	0.000	0.997	0.003
N30.4 Irradiation cystitis	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.003
F41.2 Mixed anxiety and depressive disorder	0.000	0.997	0.003
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.997	0.003
L03.1 Cellulitis of other parts of limb	0.003	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
T93.2 Sequelae of other fractures of lower limb	0.000	0.997	0.003
N42.9 Disorder of prostate, unspecified	0.003	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.997	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
I73.0 Raynaud's syndrome	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.997	0.003
N94.1 Dyspareunia	0.000	0.997	0.003
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.002
H02.3 Blepharochalasis	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.998	0.002
S52.50 Fracture of lower end of radius (closed)	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
C79 Secondary malignant neoplasm of other sites	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.998	0.002
T51.0 Ethanol	0.000	0.998	0.002
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
L03.9 Cellulitis, unspecified	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
N20.1 Calculus of ureter	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.000	0.998	0.002
M22.8 Other disorders of patella	0.002	0.998	0.000
K37 Unspecified appendicitis	0.000	0.998	0.002
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.998	0.002
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.998	0.002
J38.7 Other diseases of larynx	0.000	0.998	0.002
R60.0 Localised oedema	0.000	0.998	0.002
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
M51 Other intervertebral disk disorders	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
L81.4 Other melanin hyperpigmentation	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.000	0.998	0.002
L05.9 Pilonidal cyst without abscess	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
L05 Pilonidal cyst	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.998	0.001
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
M51.3 Other specified intervertebral disk degeneration	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.998	0.001
S82.8 Fractures of other parts of lower leg	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.001
T93.0 Sequelae of open wound of lower limb	0.000	0.998	0.001
F40 Phobic anxiety disorders	0.000	0.998	0.002
I20.8 Other forms of angina pectoris	0.000	0.998	0.002
B37.0 Candidal stomatitis	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.000	0.998	0.001
I34.2 Nonrheumatic mitral (valve) stenosis	0.001	0.998	0.000
J38.3 Other diseases of vocal cords	0.000	0.998	0.002
M22.2 Patellofemoral disorders	0.002	0.998	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.001	0.998	0.000
Z75.5 Holiday relief care	0.000	0.998	0.002
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.998	0.001
N81.1 Cystocele	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.001
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.001	0.998	0.000
M22.3 Other derangements of patella	0.001	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.001
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.998	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.001
T93.1 Sequelae of fracture of femur	0.000	0.998	0.001
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.998	0.000
M51.4 Schmorl's nodes	0.001	0.998	0.000
F99 Mental disorder, not otherwise specified	0.001	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
M22 Disorders of patella	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.001	0.999	0.000
M24.0 Loose body in joint	0.001	0.999	0.000
N42.8 Other specified disorders of prostate	0.001	0.999	0.000
T51 Toxic effect of alcohol	0.000	0.999	0.001
M24.5 Contracture of joint	0.001	0.999	0.000
N60.0 Solitary cyst of breast	0.000	0.999	0.001
R20.2 Paraesthesia of skin	0.001	0.999	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.001	0.999	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.999	0.001
S82.86 Maisonneuve's fracture	0.000	0.999	0.001
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.999	0.001
J38.2 Nodules of vocal cords	0.000	0.999	0.001
M51.8 Other specified intervertebral disk disorders	0.001	0.999	0.000
T45.4 Iron and its compounds	0.000	0.999	0.001
T51.9 Alcohol, unspecified	0.000	0.999	0.001
R53 Malaise and fatigue	0.000	0.999	0.001
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.001	0.999	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.001	0.999	0.000
M54.14 Radiculopathy (Thoracic region)	0.000	0.999	0.001
D73.0 Hyposplenism	0.000	0.999	0.001
R82 Other abnormal findings in urine	0.001	0.999	0.000
E11.3 With ophthalmic complications	0.000	0.999	0.001
F40.1 Social phobias	0.000	0.999	0.001
M24.9 Joint derangement, unspecified	0.001	0.999	0.000
M54.1 Radiculopathy	0.000	0.999	0.001
R82.4 Acetonuria	0.001	0.999	0.000
S52.5 Fracture of lower end of radius	0.001	0.999	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.999	0.001
M24.55 Contracture of joint (Pelvic region and thigh)	0.001	0.999	0.000
M51.9 Intervertebral disk disorder, unspecified	0.001	0.999	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.999	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.999	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.999	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.999	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.999	0.001
M24.56 Contracture of joint (Lower leg)	0.001	0.999	0.000
M24.7 Protrusio acetabuli	0.001	0.999	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.999	0.001
R82.7 Abnormal findings on microbiological examination of urine	0.001	0.999	0.000
W55.0 Home	0.000	0.999	0.001
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.999	0.001
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.999	0.001
N20 Calculus of kidney and ureter	0.001	0.999	0.000
M22.9 Disorder of patella, unspecified	0.001	0.999	0.000
M22.0 Recurrent dislocation of patella	0.001	0.999	0.000
M95.0 Acquired deformity of nose	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.999	0.001
O62.0 Primary inadequate contractions	0.000	0.999	0.001
L01 Impetigo	0.001	0.999	0.000
M24.52 Contracture of joint (Upper arm)	0.001	0.999	0.000
F40.0 Agoraphobia	0.000	0.999	0.001
K12.2 Cellulitis and abscess of mouth	0.000	0.999	0.001
M22.1 Recurrent subluxation of patella	0.001	0.999	0.000
R22.2 Localised swelling, mass and lump, trunk	0.001	0.999	0.000
T47.4 Other laxatives	0.000	0.999	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.999	0.001
Z42.1 Follow-up care involving plastic surgery of breast	0.001	0.999	0.000
N42 Other disorders of prostate	0.001	0.999	0.000
M24.09 Loose body in joint (Site unspecified)	0.001	0.999	0.000
M24.08 Loose body in joint (Other)	0.001	0.999	0.000
M24.00 Loose body in joint (Multiple sites)	0.001	0.999	0.000
M24.54 Contracture of joint (Hand)	0.001	0.999	0.000
M24.94 Joint derangement, unspecified (Hand)	0.001	0.999	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.999	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.999	0.001
C77.0 Lymph nodes of head, face and neck	0.000	0.999	0.001
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.999	0.001
E23.7 Disorder of pituitary gland, unspecified	0.000	0.999	0.001
H90.3 Sensorineural hearing loss, bilateral	0.001	0.999	0.000
I51.0 Cardiac septal defect, acquired	0.001	0.999	0.000
T51.8 Other alcohols	0.000	0.999	0.001
T51.3 Fusel oil	0.000	0.999	0.001
T51.2 2-Propanol	0.000	0.999	0.001
T51.1 Methanol	0.000	0.999	0.001
L00 Staphylococcal scalded skin syndrome	0.001	0.999	0.000
M24.06 Loose body in joint-Lower leg	0.001	0.999	0.000
M24.03 Loose body in joint (Forearm)	0.001	0.999	0.000
M24.59 Contracture of joint (Site unspecified)	0.001	0.999	0.000
M24.58 Contracture of joint (Other)	0.001	0.999	0.000
M24.53 Contracture of joint (Forearm)	0.001	0.999	0.000
M24.50 Contracture of joint (Multiple sites)	0.001	0.999	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.999	0.001
F05.1 Delirium superimposed on dementia	0.000	0.999	0.001
N42.3 Dysplasia of prostate	0.001	0.999	0.000
N42.0 Calculus of prostate	0.001	0.999	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.999	0.001
S61.1 Open wound of finger(s) with damage to nail	0.001	0.999	0.000
Z52.4 Kidney donor	0.001	0.999	0.000
I51 Complications and ill-defined descriptions of heart disease	0.001	0.999	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.999	0.001
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.01 Loose body in joint (Shoulder region)	0.001	0.999	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.999	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.999	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.001	0.999	0.000
M24.6 Ankylosis of joint	0.001	0.999	0.000
N03.9 Unspecified	0.001	0.999	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R82.3 Haemoglobinuria	0.001	0.999	0.000
R82.2 Biliuria	0.001	0.999	0.000
R82.0 Chyluria	0.001	0.999	0.000
M24.04 Loose body in joint (Hand)	0.001	0.999	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.999	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.999	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.999	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.999	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.999	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.999	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.999	0.001
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.999	0.001
M84.03 Malunion of fracture (Forearm)	0.000	0.999	0.001
C77.3 Axillary and upper limb lymph nodes	0.000	0.999	0.001
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.999	0.001
I27.2 Other secondary pulmonary hypertension	0.000	0.999	0.001
L01.0 Impetigo [any organism] [any site]	0.001	0.999	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.001	0.999	0.000
N20.9 Urinary calculus, unspecified	0.001	0.999	0.000
N21.0 Calculus in bladder	0.001	0.999	0.000
T47.0 Histamine H(2)-receptor antagonists	0.000	0.999	0.001
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.999	0.001
H90 Conductive and sensorineural hearing loss	0.001	0.999	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.999	0.001
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.999	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.999	0.001
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.999	0.001
J92.0 Pleural plaque with presence of asbestos	0.001	0.999	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.999	0.000
M24.2 Disorder of ligament	0.001	0.999	0.000
O62.1 Secondary uterine inertia	0.000	0.999	0.001
O80.0 Spontaneous vertex delivery	0.000	0.999	0.001
R82.1 Myoglobinuria	0.001	0.999	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.999	0.001
M22.10 Recurrent subluxation of patella, unspecified knee	0.001	0.999	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.999	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.999	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.999	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.999	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.999	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.999	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.999	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.999	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.999	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.999	0.000
M54.59 Low back pain (Site unspecified)	0.000	0.999	0.001
L01.1 Impetiginisation of other dermatoses	0.001	0.999	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.001	0.999	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.999	0.001
M24.23 Disorder of ligament (Forearm)	0.001	0.999	0.000
M24.21 Disorder of ligament (Shoulder region)	0.001	0.999	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.999	0.000
M24.64 Ankylosis of joint (Hand)	0.001	0.999	0.000
S52.51 Fracture of lower end of radius (open)	0.001	0.999	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.999	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
M24.51 Contracture of joint (Shoulder region)	0.001	0.999	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.999	0.001
M84.06 Malunion of fracture (Lower leg)	0.000	0.999	0.001
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.999	0.001
F05.8 Other delirium	0.000	0.999	0.001
H43.3 Other vitreous opacities	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.001	0.999	0.000
M22.4 Chondromalacia patellae	0.001	0.999	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.001	0.999	0.000
N20.0 Calculus of kidney	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.999	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
T47.7 Emetics	0.000	0.999	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.999	0.001
T47.5 Digestants	0.000	0.999	0.001
T47.3 Saline and osmotic laxatives	0.000	0.999	0.001
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.999	0.001
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.999	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.999	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.999	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.999	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.999	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
E23 Hypofunction and other disorders of pituitary gland	0.000	0.999	0.001
M24.29 Disorder of ligament (Site unspecified)	0.001	0.999	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.999	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.999	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.999	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
I51.6 Cardiovascular disease, unspecified	0.001	0.999	0.000
J38.6 Stenosis of larynx	0.000	0.999	0.001
J38.0 Paralysis of vocal cords and larynx	0.000	0.999	0.001
N60.3 Fibrosclerosis of breast	0.000	0.999	0.001
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
C56 Malignant neoplasm of ovary	0.000	0.999	0.001
L04 Acute lymphadenitis	0.001	0.999	0.000
N60 Benign mammary dysplasia	0.000	0.999	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.999	0.001
M54.37 Sciatica (Lumbosacral region)	0.000	0.999	0.001
B37.4 Candidiasis of other urogenital sites	0.000	0.999	0.001
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.999	0.001
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.999	0.001
F10.8 Other mental and behavioural disorders	0.000	0.999	0.001
I51.5 Myocardial degeneration	0.001	0.999	0.000
J38.5 Laryngeal spasm	0.000	0.999	0.001
T47.2 Stimulant laxatives	0.000	0.999	0.001
M24.66 Ankylosis of joint (Lower leg)	0.001	0.999	0.000
M54.19 Radiculopathy (Site unspecified)	0.000	0.999	0.001
M54.16 Radiculopathy (Lumbar region)	0.000	0.999	0.001
C77.8 Lymph nodes of multiple regions	0.000	0.999	0.001
E23.6 Other disorders of pituitary gland	0.000	0.999	0.001
F10.4 Withdrawal state with delirium	0.000	0.999	0.001
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.001	0.999	0.000
L04.8 Acute lymphadenitis of other sites	0.001	0.999	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.999	0.001
N20.2 Calculus of kidney with calculus of ureter	0.001	0.999	0.000
O62.8 Other abnormalities of forces of labour	0.000	0.999	0.001
Y60.0 During surgical operation	0.001	0.999	0.000
Z34.8 Supervision of other normal pregnancy	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.999	0.001
B37.3 Candidiasis of vulva and vagina	0.000	0.999	0.001
B37.1 Pulmonary candidiasis	0.000	0.999	0.001
C32.0 Glottis	0.000	0.999	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.999	0.001
M24.02 Loose body in joint (Upper arm)	0.001	0.999	0.000
M24.28 Disorder of ligament (Other)	0.001	0.999	0.000
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.999	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.999	0.001
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
S42.40 Fracture of lower end of humerus (closed)	0.001	0.999	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.999	0.001
C21.1 Anal canal	0.000	0.999	0.001
C78.2 Secondary malignant neoplasm of pleura	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.999	0.001
E27.1 Primary adrenocortical insufficiency	0.000	0.999	0.001
F10.7 Residual and late-onset psychotic disorder	0.000	0.999	0.001
F10.6 Amnesic syndrome	0.000	0.999	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
L04.3 Acute lymphadenitis of lower limb	0.001	0.999	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.999	0.001
O62.2 Other uterine inertia	0.000	0.999	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.999	0.001
O62 Abnormalities of forces of labour	0.000	0.999	0.001
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.999	0.001
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.999	0.000
M24.24 Disorder of ligament (Hand)	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.999	0.001
C77.5 Intrapelvic lymph nodes	0.000	0.999	0.001
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.999	0.001
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.999	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
J38.4 Oedema of larynx	0.000	0.999	0.001
L04.0 Acute lymphadenitis of face, head and neck	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
N84.2 Polyp of vagina	0.001	0.999	0.000
T41.5 Therapeutic gases	0.000	0.999	0.001
T41.4 Anaesthetic, unspecified	0.000	0.999	0.001
T41.3 Local anaesthetics	0.000	0.999	0.001
T41.1 Intravenous anaesthetics	0.000	0.999	0.001
T41.0 Inhaled anaesthetics	0.000	0.999	0.001
T63.4 Venom of other arthropods	0.001	0.999	0.000
F29 Unspecified nonorganic psychosis	0.000	0.999	0.001
F41 Other anxiety disorders	0.000	0.999	0.001
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
I89.1 Lymphangitis	0.000	0.999	0.001
L04.1 Acute lymphadenitis of trunk	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
S82.6 Fracture of lateral malleolus	0.000	0.999	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.999	0.001
M84.08 Malunion of fracture (Other)	0.000	0.999	0.001
D18.0 Haemangioma, any site	0.000	0.999	0.001
F10.5 Psychotic disorder	0.000	0.999	0.001
F44.5 Dissociative convulsions	0.000	0.999	0.001
H91.8 Other specified hearing loss	0.001	0.999	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.999	0.001
J95.0 Tracheostomy malfunction	0.000	0.999	0.001
S64.3 Injury of digital nerve of thumb	0.000	0.999	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
T38.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
T38.7 Androgens and anabolic congeners	0.000	0.999	0.001
T38.4 Oral contraceptives	0.000	0.999	0.001
T38.2 Antithyroid drugs	0.000	0.999	0.001
T49.9 Topical agent, unspecified	0.000	0.999	0.001
T49.8 Other topical agents	0.000	0.999	0.001
T49.7 Dental drugs, topically applied	0.000	0.999	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.999	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.999	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.999	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.999	0.001
T49.2 Local astringents and local detergents	0.000	0.999	0.001
T49.1 Antipruritics	0.000	0.999	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.999	0.001
M24.19 Other articular cartilage disorders (Site unspecified)	0.001	0.999	0.000
M24.18 Other articular cartilage disorders (Other)	0.001	0.999	0.000
M24.14 Other articular cartilage disorders (Hand)	0.001	0.999	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.001	0.999	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.001	0.999	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.999	0.001
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.999	0.001
S22.20 Fracture of sternum (closed)	0.000	0.999	0.001
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.999	0.001
E23.0 Hypopituitarism	0.000	0.999	0.001
L04.9 Acute lymphadenitis, unspecified	0.001	0.999	0.000
L04.2 Acute lymphadenitis of upper limb	0.001	0.999	0.000
M95.1 Cauliflower ear	0.001	0.999	0.000
N42.2 Atrophy of prostate	0.001	0.999	0.000
R23.1 Pallor	0.001	0.999	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.999	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
T37.5 Antiviral drugs	0.000	0.999	0.001
T37.4 Anthelminthics	0.000	0.999	0.001
T37.3 Other antiprotozoal drugs	0.000	0.999	0.001
T37.1 Antimycobacterial drugs	0.000	0.999	0.001
T37.0 Sulphonamides	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
F05.0 Delirium not superimposed on dementia, so described	0.000	0.999	0.001
F10.9 Unspecified mental and behavioural disorder	0.000	0.999	0.001
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.001	0.999	0.000
M95.3 Acquired deformity of neck	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations