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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10774622
log Bayes Factor = 16.6683
Chromosome 12   position 111,833,348  (GRCh37) Explore rs10774622 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.005 0.995
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.005 0.995
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.005 0.995
Z95.1 Presence of aortocoronary bypass graft
0.000 0.005 0.995
I10-I15 Hypertensive diseases
0.000 0.007 0.993
Chapter IX Diseases of the circulatory system
0.000 0.008 0.992
I21.9 Acute myocardial infarction, unspecified
0.000 0.010 0.990
E03 Other hypothyroidism
0.000 0.018 0.982
E00-E07 Disorders of thyroid gland
0.000 0.028 0.972
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.034 0.966
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.047 0.953
I99 Other and unspecified disorders of circulatory system
0.000 0.060 0.940
Z95.4 Presence of other heart-valve replacement
0.000 0.068 0.932
E20-E35 Disorders of other endocrine glands
0.000 0.068 0.932
Z95.3 Presence of xenogenic heart valve
0.000 0.074 0.926
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.076 0.924
E27 Other disorders of adrenal gland
0.000 0.080 0.920
I25.2 Old myocardial infarction
0.000 0.081 0.919
E10 Insulin-dependent diabetes mellitus
0.000 0.082 0.918
E10-E14 Diabetes mellitus
0.000 0.082 0.918
I25.5 Ischaemic cardiomyopathy
0.000 0.091 0.909
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.092 0.908
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.095 0.905
E10.3 With ophthalmic complications
0.000 0.100 0.900
E05.9 Thyrotoxicosis, unspecified
0.000 0.105 0.895
E50-E64 Other nutritional deficiencies
0.000 0.118 0.882
I26 Pulmonary embolism
0.000 0.118 0.882
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.120 0.880
E27.1 Primary adrenocortical insufficiency
0.000 0.120 0.880
E10.9 Without complications
0.000 0.124 0.876
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.126 0.874
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.136 0.864
I22 Subsequent myocardial infarction
0.000 0.140 0.860
E28 Ovarian dysfunction
0.000 0.169 0.831
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.181 0.819
I97.1 Other functional disturbances following cardiac surgery
0.000 0.193 0.807
E61 Deficiency of other nutrient elements
0.000 0.195 0.805
E10.0 With coma
0.000 0.214 0.786
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.215 0.785
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.217 0.783
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.225 0.775
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.225 0.775
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.229 0.771
E10.6 With other specified complications
0.000 0.256 0.744
E06 Thyroiditis
0.000 0.257 0.743
E28.2 Polycystic ovarian syndrome
0.000 0.258 0.742
I24 Other acute ischaemic heart diseases
0.000 0.261 0.739
E22 Hyperfunction of pituitary gland
0.000 0.266 0.734
I23 Certain current complications following acute myocardial infarction
0.000 0.270 0.729
E10.4 With neurological complications
0.000 0.273 0.727
E27.8 Other specified disorders of adrenal gland
0.000 0.273 0.727
E53 Deficiency of other B group vitamins
0.000 0.276 0.724
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.278 0.722
E16 Other disorders of pancreatic internal secretion
0.000 0.278 0.722
E61.1 Iron deficiency
0.000 0.278 0.722
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E27.2 Addisonian crisis
0.000 0.284 0.716
Z95.2 Presence of prosthetic heart valve
0.000 0.288 0.712
I13 Hypertensive heart and renal disease
0.000 0.288 0.712
I00-I02 Acute rheumatic fever
0.000 0.288 0.711
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.289 0.711
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.708
E23 Hypofunction and other disorders of pituitary gland
0.000 0.293 0.707
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.294 0.706
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.295 0.705
E03.5 Myxoedema coma
0.000 0.296 0.704
E03.4 Atrophy of thyroid (acquired)
0.000 0.296 0.704
E03.3 Postinfectious hypothyroidism
0.000 0.296 0.704
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.296 0.704
E10.8 With unspecified complications
0.000 0.297 0.703
E03.8 Other specified hypothyroidism
0.000 0.301 0.699
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.303 0.697
E00 Congenital iodine-deficiency syndrome
0.000 0.303 0.697
E10.5 With peripheral circulatory complications
0.000 0.303 0.696
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.307 0.693
I25.4 Coronary artery aneurysm
0.000 0.308 0.691
E27.9 Disorder of adrenal gland, unspecified
0.000 0.310 0.690
I24.8 Other forms of acute ischaemic heart disease
0.000 0.323 0.677
E05.8 Other thyrotoxicosis
0.000 0.323 0.677
E20 Hypoparathyroidism
0.000 0.327 0.673
E03.1 Congenital hypothyroidism without goitre
0.000 0.329 0.671
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.332 0.668
E31 Polyglandular dysfunction
0.000 0.332 0.668
E30 Disorders of puberty, not elsewhere classified
0.000 0.332 0.668
E07 Other disorders of thyroid
0.000 0.334 0.666
E10.1 With ketoacidosis
0.000 0.337 0.663
E05.5 Thyroid crisis or storm
0.000 0.337 0.663
E05.4 Thyrotoxicosis factitia
0.000 0.337 0.663
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.337 0.663
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.337 0.663
E27.5 Adrenomedullary hyperfunction
0.000 0.340 0.659
E27.0 Other adrenocortical overactivity
0.000 0.340 0.659
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.341 0.659
E12 Malnutrition-related diabetes mellitus
0.000 0.342 0.658
I28 Other diseases of pulmonary vessels
0.000 0.343 0.657
E06.9 Thyroiditis, unspecified
0.000 0.344 0.656
E61.2 Magnesium deficiency
0.000 0.346 0.654
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.349 0.651
I97.0 Postcardiotomy syndrome
0.000 0.349 0.651
E16.2 Hypoglycaemia, unspecified
0.000 0.354 0.646
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.357 0.643
I15 Secondary hypertension
0.000 0.359 0.641
E28.3 Primary ovarian failure
0.000 0.360 0.640
I21.4 Acute subendocardial myocardial infarction
0.000 0.363 0.637
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.368 0.632
E63 Other nutritional deficiencies
0.000 0.368 0.632
E56 Other vitamin deficiencies
0.000 0.368 0.632
E51 Thiamine deficiency
0.000 0.368 0.632
E50 Vitamin A deficiency
0.000 0.368 0.632
E60 Dietary zinc deficiency
0.000 0.368 0.632
E59 Dietary selenium deficiency
0.000 0.368 0.632
E58 Dietary calcium deficiency
0.000 0.368 0.632
E54 Ascorbic acid deficiency
0.000 0.368 0.632
E52 Niacin deficiency [pellagra]
0.000 0.368 0.632
E23.2 Diabetes insipidus
0.000 0.372 0.628
E55 Vitamin D deficiency
0.000 0.380 0.620
E25 Adrenogenital disorders
0.000 0.386 0.614
I25.3 Aneurysm of heart
0.000 0.387 0.613
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.388 0.612
E53.8 Deficiency of other specified B group vitamins
0.000 0.394 0.606
E26 Hyperaldosteronism
0.000 0.397 0.603
E32 Diseases of thymus
0.000 0.398 0.602
E16.1 Other hypoglycaemia
0.000 0.399 0.601
E34 Other endocrine disorders
0.000 0.399 0.601
E28.9 Ovarian dysfunction, unspecified
0.000 0.404 0.596
E28.8 Other ovarian dysfunction
0.000 0.404 0.596
E28.1 Androgen excess
0.000 0.404 0.596
E28.0 Oestrogen excess
0.000 0.404 0.596
E15 Nondiabetic hypoglycaemic coma
0.000 0.413 0.587
I11 Hypertensive heart disease
0.000 0.414 0.586
E61.9 Deficiency of nutrient element, unspecified
0.000 0.423 0.577
E61.8 Deficiency of other specified nutrient elements
0.000 0.423 0.577
E61.7 Deficiency of multiple nutrient elements
0.000 0.423 0.577
E61.6 Vanadium deficiency
0.000 0.423 0.577
E61.5 Molybdenum deficiency
0.000 0.423 0.577
E61.4 Chromium deficiency
0.000 0.423 0.577
E61.3 Manganese deficiency
0.000 0.423 0.577
E61.0 Copper deficiency
0.000 0.423 0.577
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.423 0.577
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.437 0.563
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.445 0.555
E24 Cushing's syndrome
0.000 0.450 0.550
E40-E46 Malnutrition
0.000 0.462 0.538
I23.8 Other current complications following acute myocardial infarction
0.000 0.464 0.536
E06.4 Drug-induced thyroiditis
0.000 0.467 0.533
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.467 0.533
E06.1 Subacute thyroiditis
0.000 0.467 0.533
E06.0 Acute thyroiditis
0.000 0.467 0.533
I24.1 Dressler's syndrome
0.000 0.469 0.531
E53.9 Vitamin B deficiency, unspecified
0.000 0.473 0.527
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.473 0.527
E22.8 Other hyperfunction of pituitary gland
0.000 0.473 0.527
E21.0 Primary hyperparathyroidism
0.000 0.475 0.525
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.477 0.523
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.477 0.523
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.477 0.523
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.477 0.523
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.477 0.523
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.477 0.523
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.477 0.523
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.481 0.519
E53.1 Pyridoxine deficiency
0.000 0.481 0.519
E53.0 Riboflavin deficiency
0.000 0.481 0.519
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.482 0.518
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.482 0.518
E16.4 Abnormal secretion of gastrin
0.000 0.482 0.518
E16.3 Increased secretion of glucagon
0.000 0.482 0.518
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.489 0.510
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.489 0.510
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.489 0.510
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.489 0.510
I02 Rheumatic chorea
0.000 0.490 0.510
I01 Rheumatic fever with heart involvement
0.000 0.490 0.510
I00 Rheumatic fever without mention of heart involvement
0.000 0.490 0.510
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.493 0.507
E23.1 Drug-induced hypopituitarism
0.000 0.493 0.507
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.494 0.506
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.499 0.501
E10.7 With multiple complications
0.000 0.500 0.500
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.500 0.500
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.500 0.500
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.500 0.500
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.500 0.500
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.500 0.500
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.500 0.500
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.500 0.500
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.500 0.500
E10.2 With renal complications
0.000 0.501 0.499
E23.7 Disorder of pituitary gland, unspecified
0.000 0.502 0.498
E21.4 Other specified disorders of parathyroid gland
0.000 0.503 0.497
E21.2 Other hyperparathyroidism
0.000 0.503 0.497
E07.9 Disorder of thyroid, unspecified
0.000 0.510 0.490
Z95.0 Presence of cardiac pacemaker
0.000 0.510 0.490
E20.9 Hypoparathyroidism, unspecified
0.000 0.512 0.487
E20.8 Other hypoparathyroidism
0.000 0.517 0.482
E20.1 Pseudohypoparathyroidism
0.000 0.517 0.482
E20.0 Idiopathic hypoparathyroidism
0.000 0.517 0.482
E22.1 Hyperprolactinaemia
0.000 0.519 0.481
I22.8 Subsequent myocardial infarction of other sites
0.000 0.520 0.480
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.520 0.480
E30.9 Disorder of puberty, unspecified
0.000 0.521 0.479
E30.8 Other disorders of puberty
0.000 0.521 0.479
E30.1 Precocious puberty
0.000 0.521 0.479
E30.0 Delayed puberty
0.000 0.521 0.479
E31.9 Polyglandular dysfunction, unspecified
0.000 0.521 0.479
E31.8 Other polyglandular dysfunction
0.000 0.521 0.479
E31.1 Polyglandular hyperfunction
0.000 0.521 0.479
E31.0 Autoimmune polyglandular failure
0.000 0.521 0.479
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.521 0.479
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.521 0.479
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.521 0.479
I28.8 Other specified diseases of pulmonary vessels
0.000 0.522 0.478
E07.1 Dyshormogenetic goitre
0.000 0.522 0.478
E07.0 Hypersecretion of calcitonin
0.000 0.522 0.478
E29 Testicular dysfunction
0.001 0.523 0.477
E12.9 Without complications
0.000 0.528 0.472
E12.8 With unspecified complications
0.000 0.528 0.472
E12.7 With multiple complications
0.000 0.528 0.472
E12.6 With other specified complications
0.000 0.528 0.472
E12.5 With peripheral circulatory complications
0.000 0.528 0.472
E12.4 With neurological complications
0.000 0.528 0.472
E12.3 With ophthalmic complications
0.000 0.528 0.472
E12.2 With renal complications
0.000 0.528 0.472
E12.1 With ketoacidosis
0.000 0.528 0.472
E12.0 With coma
0.000 0.528 0.472
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.529 0.471
I28.1 Aneurysm of pulmonary artery
0.000 0.529 0.471
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.529 0.471
E23.6 Other disorders of pituitary gland
0.000 0.533 0.467
E06.3 Autoimmune thyroiditis
0.000 0.537 0.463
I15.1 Hypertension secondary to other renal disorders
0.000 0.539 0.461
I15.8 Other secondary hypertension
0.000 0.540 0.460
I15.2 Hypertension secondary to endocrine disorders
0.000 0.540 0.460
I15.0 Renovascular hypertension
0.000 0.540 0.460
E50.9 Vitamin A deficiency, unspecified
0.000 0.546 0.453
E50.8 Other manifestations of vitamin A deficiency
0.000 0.546 0.453
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.546 0.453
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.546 0.453
E50.5 Vitamin A deficiency with night blindness
0.000 0.546 0.453
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.546 0.453
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.546 0.453
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.546 0.453
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.546 0.453
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.546 0.453
E51.9 Thiamine deficiency, unspecified
0.000 0.546 0.453
E51.8 Other manifestations of thiamine deficiency
0.000 0.546 0.453
E51.2 Wernicke's encephalopathy
0.000 0.546 0.453
E51.1 Beriberi
0.000 0.546 0.453
E56.9 Vitamin deficiency, unspecified
0.000 0.546 0.453
E56.8 Deficiency of other vitamins
0.000 0.546 0.453
E56.1 Deficiency of vitamin K
0.000 0.546 0.453
E56.0 Deficiency of vitamin E
0.000 0.546 0.453
E63.9 Nutritional deficiency, unspecified
0.000 0.546 0.453
E63.8 Other specified nutritional deficiencies
0.000 0.546 0.453
E63.1 Imbalance of constituents of food intake
0.000 0.546 0.453
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.546 0.453
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.546 0.453
E64.8 Sequelae of other nutritional deficiencies
0.000 0.546 0.453
E64.3 Sequelae of rickets
0.000 0.546 0.453
E64.2 Sequelae of vitamin C deficiency
0.000 0.546 0.453
E64.1 Sequelae of vitamin A deficiency
0.000 0.546 0.453
E64.0 Sequelae of protein-energy malnutrition
0.000 0.546 0.453
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.547 0.452
E06.5 Other chronic thyroiditis
0.000 0.552 0.448
E55.0 Rickets, active
0.000 0.555 0.445
E34.0 Carcinoid syndrome
0.000 0.557 0.443
E25.9 Adrenogenital disorder, unspecified
0.000 0.560 0.440
E25.8 Other adrenogenital disorders
0.000 0.560 0.440
E34.9 Endocrine disorder, unspecified
0.000 0.560 0.440
E13 Other specified diabetes mellitus
0.001 0.562 0.437
E55.9 Vitamin D deficiency, unspecified
0.000 0.567 0.433
E26.9 Hyperaldosteronism, unspecified
0.000 0.568 0.432
E26.8 Other hyperaldosteronism
0.000 0.568 0.432
E26.1 Secondary hyperaldosteronism
0.000 0.568 0.432
E32.9 Disease of thymus, unspecified
0.000 0.568 0.431
E32.1 Abscess of thymus
0.000 0.568 0.431
E32.0 Persistent hyperplasia of thymus
0.000 0.568 0.431
E07.8 Other specified disorders of thyroid
0.000 0.568 0.431
E34.5 Androgen resistance syndrome
0.000 0.569 0.431
E34.4 Constitutional tall stature
0.000 0.569 0.431
E34.3 Short stature, not elsewhere classified
0.000 0.569 0.431
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.569 0.431
E34.1 Other hypersecretion of intestinal hormones
0.000 0.569 0.431
I05-I09 Chronic rheumatic heart diseases
0.000 0.571 0.429
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.576 0.424
E21.3 Hyperparathyroidism, unspecified
0.000 0.582 0.418
E22.0 Acromegaly and pituitary gigantism
0.000 0.586 0.414
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.589 0.411
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.593 0.407
I80 Phlebitis and thrombophlebitis
0.000 0.598 0.402
E24.0 Pituitary-dependent Cushing's disease
0.000 0.598 0.401
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.602 0.398
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
I98.0 Cardiovascular syphilis
0.000 0.602 0.398
E24.8 Other Cushing's syndrome
0.000 0.605 0.394
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.605 0.394
E24.3 Ectopic ACTH syndrome
0.000 0.605 0.394
E24.1 Nelson's syndrome
0.000 0.605 0.394
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.611 0.388
I15.9 Seconday hypertension, unspecified
0.000 0.612 0.388
E23.0 Hypopituitarism
0.000 0.614 0.386
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.614 0.386
E45 Retarded development following protein-energy malnutrition
0.000 0.614 0.386
E43 Unspecified severe protein-energy malnutrition
0.000 0.614 0.386
E42 Marasmic kwashiorkor
0.000 0.614 0.386
E41 Nutritional marasmus
0.000 0.614 0.386
E40 Kwashiorkor
0.000 0.614 0.386
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.614 0.386
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.618 0.382
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.626 0.374
I12 Hypertensive renal disease
0.000 0.628 0.372
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.628 0.371
E26.0 Primary hyperaldosteronism
0.000 0.633 0.367
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.634 0.366
I01.8 Other acute rheumatic heart disease
0.000 0.634 0.366
I01.2 Acute rheumatic myocarditis
0.000 0.634 0.366
I01.1 Acute rheumatic endocarditis
0.000 0.634 0.366
I01.0 Acute rheumatic pericarditis
0.000 0.634 0.366
I02.9 Rheumatic chorea without heart involvement
0.000 0.634 0.366
I02.0 Rheumatic chorea with heart involvement
0.000 0.634 0.366
E32.8 Other diseases of thymus
0.000 0.634 0.365
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.648 0.352
E24.2 Drug-induced Cushing's syndrome
0.000 0.653 0.347
I95 Hypotension
0.000 0.653 0.347
E14 Unspecified diabetes mellitus
0.000 0.655 0.345
E65-E68 Obesity and other hyperalimentation
0.000 0.657 0.343
E29.9 Testicular dysfunction, unspecified
0.001 0.658 0.342
E29.8 Other testicular dysfunction
0.001 0.658 0.342
E29.0 Testicular hyperfunction
0.001 0.658 0.342
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.659 0.340
I07 Rheumatic tricuspid valve diseases
0.000 0.660 0.340
E34.8 Other specified endocrine disorders
0.000 0.668 0.331
E24.9 Cushing's syndrome, unspecified
0.000 0.669 0.331
I20 Angina pectoris
0.000 0.673 0.327
E13.8 With unspecified complications
0.001 0.686 0.314
E13.7 With multiple complications
0.001 0.686 0.314
E13.6 With other specified complications
0.001 0.686 0.314
E13.5 With peripheral circulatory complications
0.001 0.686 0.314
E13.4 With neurological complications
0.001 0.686 0.314
E13.2 With renal complications
0.001 0.686 0.314
E13.1 With ketoacidosis
0.001 0.686 0.314
E13.0 With coma
0.001 0.686 0.314
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.688 0.312
I82 Other venous embolism and thrombosis
0.000 0.690 0.309
I20.8 Other forms of angina pectoris
0.000 0.702 0.298
I95.2 Hypotension due to drugs
0.000 0.703 0.297
E13.3 With ophthalmic complications
0.001 0.714 0.285
I06 Rheumatic aortic valve diseases
0.000 0.720 0.280
I85 Oesophageal varices
0.000 0.720 0.280
E44.1 Mild protein-energy malnutrition
0.000 0.723 0.277
E44.0 Moderate protein-energy malnutrition
0.000 0.723 0.277
I07.1 Tricuspid insufficiency
0.000 0.724 0.276
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.732 0.268
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.736 0.264
E14.3 With ophthalmic complications
0.000 0.739 0.261
E04 Other non-toxic goitre
0.000 0.743 0.257
I89.1 Lymphangitis
0.000 0.744 0.256
I87 Other disorders of veins
0.000 0.745 0.255
E14.4 With neurological complications
0.000 0.747 0.253
I95.0 Idiopathic hypotension
0.000 0.748 0.252
I88 Nonspecific lymphadenitis
0.000 0.749 0.250
I86 Varicose veins of other sites
0.000 0.750 0.250
E14.5 With peripheral circulatory complications
0.000 0.751 0.248
E14.7 With multiple complications
0.000 0.753 0.247
E14.2 Withrenal complications
0.000 0.753 0.247
E14.0 With coma
0.000 0.753 0.247
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.753 0.247
E67 Other hyperalimentation
0.000 0.754 0.246
E68 Sequelae of hyperalimentation
0.000 0.754 0.246
I82.3 Embolism and thrombosis of renal vein
0.000 0.755 0.245
I08 Multiple valve diseases
0.000 0.755 0.245
I07.9 Tricuspid valve disease, unspecified
0.000 0.756 0.244
I07.8 Other tricuspid valve diseases
0.000 0.756 0.244
I07.2 Tricuspid stenosis with insufficiency
0.000 0.756 0.244
I07.0 Tricuspid stenosis
0.000 0.756 0.244
I95.8 Other hypotension
0.000 0.757 0.243
I09 Other rheumatic heart diseases
0.001 0.759 0.241
E46 Unspecified protein-energy malnutrition
0.000 0.759 0.241
E14.1 With ketoacidosis
0.000 0.760 0.240
I82.8 Embolism and thrombosis of other specified veins
0.000 0.761 0.239
I05 Rheumatic mitral valve diseases
0.000 0.762 0.237
I12.9 Hypertensive renal disease without renal failure
0.000 0.766 0.234
E14.6 With other specified complications
0.000 0.768 0.231
I85.0 Oesophageal varices with bleeding
0.000 0.769 0.231
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.776 0.224
I86.4 Gastric varices
0.000 0.778 0.222
I82.1 Thrombophlebitis migrans
0.000 0.778 0.222
I82.0 Budd-Chiari syndrome
0.000 0.778 0.222
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.787 0.213
I82.2 Embolism and thrombosis of vena cava
0.000 0.790 0.210
I27 Other pulmonary heart diseases
0.000 0.791 0.209
I87.8 Other specified disorders of veins
0.000 0.792 0.208
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.796 0.204
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.796 0.203
E14.8 With unspecified complications
0.000 0.797 0.202
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.799 0.201
I06.8 Other rheumatic aortic valve diseases
0.000 0.799 0.201
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.799 0.201
I06.0 Rheumatic aortic stenosis
0.000 0.799 0.201
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.799 0.201
E04.0 Non-toxic diffuse goitre
0.000 0.803 0.197
E65 Localised adiposity
0.000 0.806 0.194
I05.2 Mitral stenosis with insufficiency
0.000 0.806 0.194
E04.8 Other specified non-toxic goitre
0.000 0.816 0.184
I87.9 Disorder of vein, unspecified
0.000 0.817 0.183
I87.0 Postphlebitic syndrome
0.000 0.817 0.183
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.819 0.181
I88.8 Other nonspecific lymphadenitis
0.000 0.820 0.180
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.820 0.180
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.820 0.180
I86.3 Vulval varices
0.000 0.821 0.179
I86.0 Sublingual varices
0.000 0.821 0.179
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.821 0.179
E67.8 Other specified hyperalimentation
0.000 0.823 0.177
E67.3 Hypervitaminosis D
0.000 0.823 0.177
E67.2 Megavitamin-B6 syndrome
0.000 0.823 0.177
E67.1 Hypercarotenaemia
0.000 0.823 0.177
E67.0 Hypervitaminosis A
0.000 0.823 0.177
E04.9 Non-toxic goitre, unspecified
0.000 0.824 0.176
I08.9 Multiple valve disease, unspecified
0.000 0.824 0.176
E70-E90 Metabolic disorders
0.000 0.825 0.175
I05.0 Mitral stenosis
0.000 0.825 0.175
I06.1 Rheumatic aortic insufficiency
0.000 0.826 0.174
I09.8 Other specified rheumatic heart diseases
0.001 0.827 0.173
I09.2 Chronic rheumatic pericarditis
0.001 0.827 0.173
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.827 0.173
I09.0 Rheumatic myocarditis
0.001 0.827 0.173
I05.8 Other mitral valve diseases
0.000 0.829 0.170
I08.8 Other multiple valve diseases
0.000 0.830 0.170
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.833 0.167
I86.2 Pelvic varices
0.000 0.835 0.164
I60-I69 Cerebrovascular diseases
0.000 0.836 0.164
E86 Volume depletion
0.000 0.840 0.160
E13.9 Without complications
0.001 0.842 0.157
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.843 0.157
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.845 0.155
E85 Amyloidosis
0.000 0.848 0.152
E29.1 Testicular hypofunction
0.001 0.848 0.151
I81 Portal vein thrombosis
0.000 0.849 0.151
I27.1 Kyphoscoliotic heart disease
0.000 0.850 0.150
I05.1 Rheumatic mitral insufficiency
0.000 0.850 0.149
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.854 0.146
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.856 0.144
I27.8 Other specified pulmonary heart diseases
0.000 0.856 0.144
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.864 0.135
I83 Varicose veins of lower extremities
0.000 0.865 0.135
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.867 0.133
I86.1 Scrotal varices
0.000 0.868 0.132
I87.1 Compression of vein
0.000 0.870 0.130
I85.9 Oesophageal varices without bleeding
0.000 0.871 0.129
E73 Lactose intolerance
0.000 0.871 0.129
I78 Diseases of capillaries
0.000 0.871 0.129
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.871 0.129
I72 Other aneurysm
0.000 0.872 0.128
E84 Cystic fibrosis
0.000 0.873 0.127
I70 Atherosclerosis
0.000 0.874 0.126
E79 Disorders of purine and pyrimidine metabolism
0.000 0.874 0.126
E77 Disorders of glycoprotein metabolism
0.000 0.874 0.126
E76 Disorders of glycosaminoglycan metabolism
0.000 0.874 0.126
E72 Other disorders of amino-acid metabolism
0.000 0.874 0.126
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.874 0.126
E70 Disorders of aromatic amino-acid metabolism
0.000 0.874 0.126
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.874 0.126
E85.4 Organ-limited amyloidosis
0.000 0.874 0.126
E80.4 Gilbert's syndrome
0.000 0.875 0.125
I77 Other disorders of arteries and arterioles
0.000 0.875 0.125
E85.9 Amyloidosis, unspecified
0.000 0.875 0.125
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.875 0.124
E11 Non-insulin-dependent diabetes mellitus
0.000 0.876 0.124
I08.0 Disorders of both mitral and aortic valves
0.000 0.879 0.121
I62 Other nontraumatic intracranial haemorrhage
0.000 0.883 0.117
I77.6 Arteritis, unspecified
0.000 0.883 0.117
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.885 0.115
I73 Other peripheral vascular diseases
0.000 0.887 0.113
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.887 0.113
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.887 0.113
I27.0 Primary pulmonary hypertension
0.000 0.887 0.113
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.887 0.113
I20.0 Unstable angina
0.000 0.890 0.110
E85.8 Other amyloidosis
0.000 0.891 0.109
E85.3 Secondary systemic amyloidosis
0.000 0.891 0.109
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.891 0.109
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.891 0.109
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.891 0.109
E74 Other disorders of carbohydrate metabolism
0.000 0.891 0.109
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.892 0.108
I09.9 Rheumatic heart disease, unspecified
0.001 0.893 0.106
I72.8 Aneurysm of other specified arteries
0.000 0.894 0.106
I63 Cerebral infarction
0.000 0.894 0.106
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.895 0.105
E80.6 Other disorders of bilirubin metabolism
0.000 0.895 0.105

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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