TreeWAS – Variant ID: rs10782174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.091	0.909	0.000
G47.9 Sleep disorder, unspecified	0.000	0.914	0.086
G47 Sleep disorders	0.000	0.946	0.054
E05 Thyrotoxicosis [hyperthyroidism]	0.052	0.948	0.000
G47.8 Other sleep disorders	0.000	0.950	0.050
O80.0 Spontaneous vertex delivery	0.049	0.951	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.956	0.044
E05.0 Thyrotoxicosis with diffuse goitre	0.043	0.957	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.958	0.042
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.040	0.959	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.960	0.040
E05.5 Thyroid crisis or storm	0.038	0.962	0.000
E05.4 Thyrotoxicosis factitia	0.038	0.962	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.038	0.962	0.000
G47.4 Narcolepsy and cataplexy	0.000	0.962	0.038
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.037	0.963	0.000
E05.8 Other thyrotoxicosis	0.036	0.964	0.000
O80 Single spontaneous delivery	0.029	0.971	0.000
C54.1 Endometrium	0.000	0.975	0.025
O80.9 Single spontaneous delivery, unspecified	0.023	0.977	0.000
O80.8 Other single spontaneous delivery	0.022	0.978	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.979	0.021
O80.1 Spontaneous breech delivery	0.021	0.979	0.000
F33 Recurrent depressive disorder	0.000	0.983	0.017
F30-F39 Mood [affective] disorders	0.000	0.983	0.017
F31 Bipolar affective disorder	0.000	0.984	0.016
F30 Manic episode	0.000	0.984	0.016
F33.9 Recurrent depressive disorder, unspecified	0.000	0.984	0.016
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.985	0.015
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.985	0.015
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.985	0.015
F31.9 Bipolar affective disorder, unspecified	0.000	0.985	0.015
F32 Depressive episode	0.000	0.986	0.014
F30.9 Manic episode, unspecified	0.000	0.986	0.014
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.987	0.013
F38 Other mood [affective] disorders	0.000	0.987	0.013
F34 Persistent mood [affective] disorders	0.000	0.987	0.013
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.987	0.013
F32.1 Moderate depressive episode	0.000	0.987	0.013
F39 Unspecified mood [affective] disorder	0.000	0.987	0.013
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.987	0.013
F30.0 Hypomania	0.000	0.987	0.013
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.988	0.012
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.988	0.012
F33.8 Other recurrent depressive disorders	0.000	0.988	0.012
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.988	0.012
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.988	0.012
F31.8 Other bipolar affective disorders	0.000	0.988	0.012
F30.2 Mania with psychotic symptoms	0.000	0.988	0.012
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.988	0.012
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.988	0.012
F30.8 Other manic episodes	0.000	0.989	0.011
F32.0 Mild depressive episode	0.000	0.989	0.011
C54 Malignant neoplasm of corpus uteri	0.000	0.989	0.011
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.989	0.011
R47.0 Dysphasia and aphasia	0.000	0.989	0.011
F34.1 Dysthymia	0.000	0.989	0.011
F31.7 Bipolar affective disorder, currently in remission	0.000	0.989	0.011
F30.1 Mania without psychotic symptoms	0.000	0.989	0.010
F32.8 Other depressive episodes	0.000	0.990	0.010
F38.0 Other single mood [affective] disorders	0.000	0.990	0.010
F38.8 Other specified mood [affective] disorders	0.000	0.990	0.010
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.990	0.010
F38.1 Other recurrent mood [affective] disorders	0.000	0.990	0.009
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.990	0.009
F34.8 Other persistent mood [affective] disorders	0.000	0.990	0.009
F34.0 Cyclothymia	0.000	0.991	0.008
K05.3 Chronic periodontitis	0.009	0.991	0.000
C54.8 Overlapping lesion of corpus uteri	0.000	0.992	0.008
C54.3 Fundus uteri	0.000	0.992	0.008
C54.2 Myometrium	0.000	0.992	0.008
C54.0 Isthmus uteri	0.000	0.992	0.008
C54.9 Corpus uteri, unspecified	0.000	0.992	0.008
E00-E07 Disorders of thyroid gland	0.007	0.993	0.000
G47.3 Sleep apnoea	0.000	0.993	0.007
K05 Gingivitis and periodontal diseases	0.007	0.993	0.000
K05.6 Periodontal disease, unspecified	0.007	0.993	0.000
E07 Other disorders of thyroid	0.006	0.994	0.000
K05.0 Acute gingivitis	0.006	0.994	0.000
R54 Senility	0.000	0.994	0.006
E07.9 Disorder of thyroid, unspecified	0.006	0.994	0.000
K05.4 Periodontosis	0.006	0.994	0.000
O80-O84 Delivery	0.006	0.994	0.000
K05.1 Chronic gingivitis	0.005	0.995	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E00 Congenital iodine-deficiency syndrome	0.005	0.995	0.000
K05.2 Acute periodontitis	0.005	0.995	0.000
K05.5 Other periodontal diseases	0.005	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.995	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.005	0.995	0.000
E07.8 Other specified disorders of thyroid	0.005	0.995	0.000
E07.1 Dyshormogenetic goitre	0.005	0.995	0.000
E07.0 Hypersecretion of calcitonin	0.005	0.995	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.005	0.995	0.000
I20.8 Other forms of angina pectoris	0.005	0.995	0.000
E06 Thyroiditis	0.004	0.996	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.004	0.996	0.000
O83 Other assisted single delivery	0.004	0.996	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.004	0.996	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.004	0.996	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.004	0.996	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.004	0.996	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.004	0.996	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.004	0.996	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.004	0.996	0.000
O84 Multiple delivery	0.004	0.996	0.000
G40-G47 Episodic and paroxysmal disorders	0.000	0.996	0.004
K05.22 Aggressive periodontitis, generalized	0.004	0.996	0.000
E03 Other hypothyroidism	0.004	0.996	0.000
G41 Status epilepticus	0.000	0.996	0.004
O81 Single delivery by forceps and vacuum extractor	0.004	0.996	0.000
E06.4 Drug-induced thyroiditis	0.003	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.003	0.997	0.000
E06.1 Subacute thyroiditis	0.003	0.997	0.000
E06.0 Acute thyroiditis	0.003	0.997	0.000
E03.8 Other specified hypothyroidism	0.003	0.997	0.000
G41.9 Status epilepticus, unspecified	0.000	0.997	0.003
E06.5 Other chronic thyroiditis	0.003	0.997	0.000
K55.2 Angiodysplasia of colon	0.000	0.997	0.003
O83.9 Assisted single delivery, unspecified	0.003	0.997	0.000
O83.8 Other specified assisted single delivery	0.003	0.997	0.000
O83.4 Destructive operation for delivery	0.003	0.997	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.003	0.997	0.000
O83.2 Other manipulation-assisted delivery	0.003	0.997	0.000
O83.0 Breech extraction	0.003	0.997	0.000
O83.1 Other assisted breech delivery	0.003	0.997	0.000
O84.9 Multiple delivery, unspecified	0.003	0.997	0.000
O84.8 Other multiple delivery	0.003	0.997	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.003	0.997	0.000
O84.0 Multiple delivery, all spontaneous	0.003	0.997	0.000
O02.1 Missed abortion	0.000	0.997	0.003
G41.0 Grand mal status epilepticus	0.000	0.997	0.003
G44 Other headache syndromes	0.000	0.997	0.003
G41.8 Other status epilepticus	0.000	0.997	0.003
O81.3 Other and unspecified forceps delivery	0.003	0.997	0.000
O84.2 Multiple delivery, all by Caesarean section	0.003	0.997	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
E03.5 Myxoedema coma	0.003	0.997	0.000
E03.4 Atrophy of thyroid (acquired)	0.003	0.997	0.000
E03.3 Postinfectious hypothyroidism	0.003	0.997	0.000
G41.1 Petit mal status epilepticus	0.000	0.997	0.003
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.997	0.003
E03.1 Congenital hypothyroidism without goitre	0.003	0.997	0.000
G41.2 Complex partial status epilepticus	0.000	0.997	0.003
O81.5 Delivery by combination of forceps and vacuum extractor	0.003	0.997	0.000
O81.2 Mid-cavity forceps with rotation	0.003	0.997	0.000
O81.1 Mid-cavity forceps delivery	0.003	0.997	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.003	0.997	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.997	0.003
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
O81.0 Low forceps delivery	0.003	0.997	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.997	0.003
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
G44.3 Chronic posttraumatic headache	0.000	0.997	0.003
G44.8 Other specified headache syndromes	0.000	0.997	0.002
O82 Single delivery by Caesarean section	0.002	0.997	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.003	0.997	0.000
I67 Other cerebrovascular diseases	0.000	0.998	0.002
G44.1 Vascular headache, not elsewhere classified	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
N32.0 Bladder-neck obstruction	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
G46.2 Posterior cerebral artery syndrome	0.000	0.998	0.002
O02 Other abnormal products of conception	0.000	0.998	0.002
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.998	0.002
G46.6 Pure sensory lacunar syndrome	0.000	0.998	0.002
G46.5 Pure motor lacunar syndrome	0.000	0.998	0.002
G46.1 Anterior cerebral artery syndrome	0.000	0.998	0.002
G46.0 Middle cerebral artery syndrome	0.000	0.998	0.002
G46.3 Brain stem stroke syndrome	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.002	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
G46.7 Other lacunar syndromes	0.000	0.998	0.002
G46.4 Cerebellar stroke syndrome	0.000	0.998	0.002
H43.2 Crystalline deposits in vitreous body	0.000	0.998	0.002
H43 Disorders of vitreous body	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
I67.5 Moyamoya disease	0.000	0.998	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.998	0.002
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.998	0.002
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.002
O02.8 Other specified abnormal products of conception	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.000	0.998	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.000	0.998	0.002
J44.8 Other specified chronic obstructive pulmonary disease	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
C16.0 Cardia	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.000	0.998	0.002
J15.5 Pneumonia due to Escherichia coli	0.002	0.998	0.000
N84.1 Polyp of cervix uteri	0.000	0.998	0.002
W19.2 School, other institution and public administrative area	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
N19 Unspecified renal failure	0.000	0.998	0.002
R26.3 Immobility	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.998	0.002
J93.8 Other pneumothorax	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
G43 Migraine	0.000	0.998	0.002
U80.1 Methicillin resistant agent	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.998	0.002
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.001
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.001	0.998	0.000
E04 Other non-toxic goitre	0.002	0.998	0.000
S09.9 Unspecified injury of head	0.000	0.998	0.002
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.998	0.000
O14.2 HELLP syndrome	0.001	0.998	0.000
C51-C58 Malignant neoplasms of female genital organs	0.000	0.998	0.002
E23.0 Hypopituitarism	0.002	0.998	0.000
K55 Vascular disorders of intestine	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.001
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.998	0.001
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.001	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.001
G43.1 Migraine with aura [classical migraine]	0.000	0.998	0.001
K55.8 Other vascular disorders of intestine	0.000	0.998	0.001
M06.34 Rheumatoid nodule (Hand)	0.000	0.998	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.998	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.998	0.001
J93.0 Spontaneous tension pneumothorax	0.001	0.998	0.000
J93 Pneumothorax	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.001	0.998	0.000
G40.5 Special epileptic syndromes	0.000	0.998	0.001
G43.0 Migraine without aura [common migraine]	0.000	0.998	0.001
H43.1 Vitreous haemorrhage	0.000	0.998	0.001
N42.8 Other specified disorders of prostate	0.000	0.998	0.001
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.999	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.999	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.999	0.001
D59.3 Haemolytic-uraemic syndrome	0.000	0.999	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.999	0.001
R68.8 Other specified general symptoms and signs	0.000	0.999	0.001
C51 Malignant neoplasm of vulva	0.000	0.999	0.001
D07 Carcinoma in situ of other and unspecified genital organs	0.001	0.999	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.001	0.999	0.000
L91.0 Keloid scar	0.001	0.999	0.000
D07.2 Vagina	0.001	0.999	0.000
D07.1 Vulva	0.001	0.999	0.000
E04.8 Other specified non-toxic goitre	0.001	0.999	0.000
G43.3 Complicated migraine	0.000	0.999	0.001
J34.3 Hypertrophy of nasal turbinates	0.001	0.999	0.000
K72.9 Hepatic failure, unspecified	0.001	0.999	0.000
R25.3 Fasciculation	0.000	0.999	0.001
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.999	0.001
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.999	0.001
C34.0 Main bronchus	0.000	0.999	0.001
E04.0 Non-toxic diffuse goitre	0.001	0.999	0.000
L91.8 Other hypertrophic disorders of skin	0.001	0.999	0.000
G40 Epilepsy	0.000	0.999	0.001
G43.2 Status migrainosus	0.000	0.999	0.001
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.999	0.001
C58 Malignant neoplasm of placenta	0.000	0.999	0.001
I08 Multiple valve diseases	0.000	0.999	0.001
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
U80 Agent resistant to penicillin and related antibiotics	0.001	0.999	0.000
C51.9 Vulva, unspecified	0.000	0.999	0.001
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.001	0.999	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.999	0.001
G45.0 Vertebro-basilar artery syndrome	0.000	0.999	0.001
U80.0 Penicillin resistant agent	0.001	0.999	0.000
M62 Other disorders of muscle	0.001	0.999	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.001	0.999	0.000
C57.9 Female genital organ, unspecified	0.000	0.999	0.001
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.999	0.001
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.001	0.999	0.000
G45.3 Amaurosis fugax	0.000	0.999	0.001
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
O12.2 Gestational oedema with proteinuria	0.001	0.999	0.000
C44.7 Skin of lower limb, including hip	0.000	0.999	0.001
C51.0 Labium majus	0.000	0.999	0.001
D07.3 Other and unspecified female genital organs	0.001	0.999	0.000
N81.3 Complete uterovaginal prolapse	0.001	0.999	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.999	0.001
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
C57.0 Fallopian tube	0.000	0.999	0.001
D07.6 Other and unspecified male genital organs	0.001	0.999	0.000
N76.8 Other specified inflammation of vagina and vulva	0.001	0.999	0.000
C52 Malignant neoplasm of vagina	0.000	0.999	0.001
H46 Optic neuritis	0.001	0.999	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.001	0.999	0.000
C51.8 Overlapping lesion of vulva	0.000	0.999	0.001
C51.2 Clitoris	0.000	0.999	0.001
C57.7 Other specified female genital organs	0.000	0.999	0.001
C57.4 Uterine adnexa, unspecified	0.000	0.999	0.001
C57.3 Parametrium	0.000	0.999	0.001
C57.2 Round ligament	0.000	0.999	0.001
C57.1 Broad ligament	0.000	0.999	0.001
J93.1 Other spontaneous pneumothorax	0.001	0.999	0.000
O12.0 Gestational oedema	0.001	0.999	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.999	0.001
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
G31.0 Circumscribed brain atrophy	0.000	0.999	0.001
I08.9 Multiple valve disease, unspecified	0.000	0.999	0.001
M62.6 Muscle strain	0.001	0.999	0.000
M62.0 Diastasis of muscle	0.001	0.999	0.000
O15 Eclampsia	0.001	0.999	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.999	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.999	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.999	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.999	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.999	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.999	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.999	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.001	0.999	0.000
C51.1 Labium minus	0.000	0.999	0.001
D07.4 Penis	0.001	0.999	0.000
D07.0 Endometrium	0.001	0.999	0.000
I71.0 Dissection of aorta [any part]	0.000	0.999	0.001
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
N95.1 Menopausal and female climacteric states	0.000	0.999	0.001
Z11.5 Special screening examination for other viral diseases	0.000	0.999	0.001
E55 Vitamin D deficiency	0.001	0.999	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.001	0.999	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.001	0.999	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.001	0.999	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.001	0.999	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.001	0.999	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.001	0.999	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.001	0.999	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.001	0.999	0.000
G40.8 Other epilepsy	0.000	0.999	0.001
M62.4 Contracture of muscle	0.001	0.999	0.000
O12.1 Gestational proteinuria	0.001	0.999	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.999	0.001
C57.8 Overlapping lesion of female genital organs	0.000	0.999	0.001
O06.9 Complete or unspecified, without complication	0.000	0.999	0.001
O82.0 Delivery by elective Caesarean section	0.001	0.999	0.000
R07.0 Pain in throat	0.000	0.999	0.001
C53 Malignant neoplasm of cervix uteri	0.000	0.999	0.001
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.999	0.001
D05.7 Other carcinoma in situ of breast	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.000	0.999	0.001
O03.4 Incomplete, without complication	0.000	0.999	0.001
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.001	0.999	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.999	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.999	0.001
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.999	0.001
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.999	0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.999	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.999	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.999	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.999	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.999	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.999	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.999	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.999	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.999	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.999	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.999	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.001	0.999	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.999	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.999	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.999	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.999	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.999	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.999	0.000
M62.68 Muscle strain (Other)	0.001	0.999	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.999	0.000
M62.64 Muscle strain (Hand)	0.001	0.999	0.000
M62.63 Muscle strain (Forearm)	0.001	0.999	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.999	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.999	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.999	0.000
D05.0 Lobular carcinoma in situ	0.001	0.999	0.000
G43.8 Other migraine	0.000	0.999	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
C79 Secondary malignant neoplasm of other sites	0.001	0.999	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.999	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.999	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.999	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.999	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.999	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.999	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.999	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.999	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.999	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.999	0.000
M62.48 Contracture of muscle (Other)	0.001	0.999	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.999	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.999	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.999	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.999	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.999	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.999	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.999	0.000
E55.0 Rickets, active	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
N30.9 Cystitis, unspecified	0.000	0.999	0.001
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.999	0.001
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.999	0.001
E16 Other disorders of pancreatic internal secretion	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
Y85 Sequelae of transport accidents	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.999	0.001
C53.8 Overlapping lesion of cervix uteri	0.000	0.999	0.001
C53.1 Exocervix	0.000	0.999	0.001
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.001	0.999	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.001	0.999	0.000
D23.0 Skin of lip	0.000	0.999	0.001
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
R25.2 Cramp and spasm	0.000	0.999	0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.999	0.001
O06 Unspecified abortion	0.000	0.999	0.001
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.999	0.001
M62.46 Contracture of muscle (Lower leg)	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
C53.0 Endocervix	0.000	0.999	0.001
M06.0 Seronegative rheumatoid arthritis	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
O01.0 Classical hydatidiform mole	0.000	0.999	0.001
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.999	0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.001	0.999	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.999	0.001
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.001	0.999	0.000
D57.3 Sickle-cell trait	0.000	0.999	0.001
E16.1 Other hypoglycaemia	0.001	0.999	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.999	0.001
N90.4 Leukoplakia of vulva	0.001	0.999	0.000
R63.0 Anorexia	0.000	0.999	0.001
Z88.4 Personal history of allergy to anaesthetic agent	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations