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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10807055
log Bayes Factor = 39.647
Chromosome 6   position 29,384,131  (GRCh37) Explore rs10807055 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.007 0.993
E10.9 Without complications
0.000 0.010 0.990
E10.2 With renal complications
0.000 0.027 0.973
E10-E14 Diabetes mellitus
0.000 0.028 0.972
E10.1 With ketoacidosis
0.000 0.043 0.957
E13 Other specified diabetes mellitus
0.000 0.049 0.951
E13.9 Without complications
0.000 0.063 0.937
E10.4 With neurological complications
0.000 0.101 0.899
E10.0 With coma
0.000 0.202 0.798
E14 Unspecified diabetes mellitus
0.000 0.216 0.784
E10.6 With other specified complications
0.000 0.247 0.753
E10.5 With peripheral circulatory complications
0.000 0.255 0.744
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.266 0.734
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.271 0.729
E16 Other disorders of pancreatic internal secretion
0.000 0.273 0.727
E16.2 Hypoglycaemia, unspecified
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.276 0.724
E12 Malnutrition-related diabetes mellitus
0.000 0.303 0.697
E00-E07 Disorders of thyroid gland
0.000 0.307 0.693
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.310 0.690
E05.9 Thyrotoxicosis, unspecified
0.000 0.317 0.683
E13.8 With unspecified complications
0.000 0.318 0.682
E13.7 With multiple complications
0.000 0.318 0.682
E13.6 With other specified complications
0.000 0.318 0.682
E13.5 With peripheral circulatory complications
0.000 0.318 0.682
E13.4 With neurological complications
0.000 0.318 0.682
E13.2 With renal complications
0.000 0.318 0.682
E13.1 With ketoacidosis
0.000 0.318 0.682
E13.0 With coma
0.000 0.318 0.682
E13.3 With ophthalmic complications
0.000 0.321 0.679
E14.9 Without complications
0.000 0.356 0.644
E16.1 Other hypoglycaemia
0.000 0.382 0.618
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.390 0.610
E14.2 Withrenal complications
0.000 0.391 0.609
E14.4 With neurological complications
0.000 0.407 0.593
E05.8 Other thyrotoxicosis
0.000 0.411 0.588
E14.8 With unspecified complications
0.000 0.426 0.574
K90 Intestinal malabsorption
0.000 0.429 0.570
E14.7 With multiple complications
0.000 0.438 0.562
E14.6 With other specified complications
0.000 0.438 0.562
E14.5 With peripheral circulatory complications
0.000 0.438 0.562
E14.0 With coma
0.000 0.438 0.562
E14.1 With ketoacidosis
0.000 0.438 0.562
E11 Non-insulin-dependent diabetes mellitus
0.000 0.468 0.532
E10.8 With unspecified complications
0.000 0.469 0.531
E15 Nondiabetic hypoglycaemic coma
0.000 0.477 0.523
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.478 0.521
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.478 0.521
E16.4 Abnormal secretion of gastrin
0.000 0.478 0.521
E16.3 Increased secretion of glucagon
0.000 0.478 0.521
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.485 0.515
E12.9 Without complications
0.000 0.500 0.500
E12.8 With unspecified complications
0.000 0.500 0.500
E12.7 With multiple complications
0.000 0.500 0.500
E12.6 With other specified complications
0.000 0.500 0.500
E12.5 With peripheral circulatory complications
0.000 0.500 0.500
E12.4 With neurological complications
0.000 0.500 0.500
E12.3 With ophthalmic complications
0.000 0.500 0.500
E12.2 With renal complications
0.000 0.500 0.500
E12.1 With ketoacidosis
0.000 0.500 0.500
E12.0 With coma
0.000 0.500 0.500
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.503 0.497
E00 Congenital iodine-deficiency syndrome
0.000 0.503 0.497
E05.5 Thyroid crisis or storm
0.000 0.505 0.495
E05.4 Thyrotoxicosis factitia
0.000 0.505 0.495
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.505 0.495
E11.2 With renal complications
0.000 0.513 0.487
E40-E46 Malnutrition
0.000 0.526 0.473
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.527 0.473
E11.0 With coma
0.000 0.535 0.465
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.545 0.455
E14.3 With ophthalmic complications
0.000 0.547 0.453
K90.9 Intestinal malabsorption, unspecified
0.000 0.551 0.449
E07 Other disorders of thyroid
0.000 0.554 0.446
E11.6 With other specified complications
0.000 0.569 0.431
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.578 0.422
K90.3 Pancreatic steatorrhoea
0.000 0.591 0.409
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.591 0.409
K90.1 Tropical sprue
0.000 0.591 0.409
K90.8 Other intestinal malabsorption
0.000 0.602 0.398
E11.7 With multiple complications
0.000 0.618 0.381
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.624 0.376
E03 Other hypothyroidism
0.000 0.628 0.372
E04 Other non-toxic goitre
0.000 0.631 0.368
E04.9 Non-toxic goitre, unspecified
0.000 0.643 0.357
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.644 0.356
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.644 0.356
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.644 0.356
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.644 0.356
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.644 0.356
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.644 0.356
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.644 0.356
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.644 0.356
E07.8 Other specified disorders of thyroid
0.000 0.648 0.352
E06 Thyroiditis
0.000 0.650 0.349
K51 Ulcerative colitis
0.349 0.651 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.657 0.343
E11.1 With ketoacidosis
0.000 0.659 0.341
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.660 0.339
E45 Retarded development following protein-energy malnutrition
0.000 0.660 0.339
E43 Unspecified severe protein-energy malnutrition
0.000 0.660 0.339
E42 Marasmic kwashiorkor
0.000 0.660 0.339
E41 Nutritional marasmus
0.000 0.660 0.339
E40 Kwashiorkor
0.000 0.660 0.339
K51.9 Ulcerative colitis, unspecified
0.340 0.660 0.000
K51.2 Ulcerative (chronic) proctitis
0.337 0.663 0.000
K51.4 Pseudopolyposis of colon
0.336 0.664 0.000
E11.4 With neurological complications
0.000 0.665 0.335
E11.5 With peripheral circulatory complications
0.000 0.670 0.330
E07.1 Dyshormogenetic goitre
0.000 0.680 0.320
E07.0 Hypersecretion of calcitonin
0.000 0.680 0.320
K51.3 Ulcerative (chronic) rectosigmoiditis
0.320 0.680 0.000
E11.8 With unspecified complications
0.000 0.683 0.317
E50-E64 Other nutritional deficiencies
0.000 0.690 0.310
E03.8 Other specified hypothyroidism
0.000 0.705 0.295
E23 Hypofunction and other disorders of pituitary gland
0.000 0.706 0.294
E46 Unspecified protein-energy malnutrition
0.000 0.713 0.287
K51.0 Ulcerative (chronic) enterocolitis
0.287 0.713 0.000
E20 Hypoparathyroidism
0.000 0.717 0.283
E24 Cushing's syndrome
0.000 0.717 0.283
E03.1 Congenital hypothyroidism without goitre
0.000 0.718 0.282
E06.9 Thyroiditis, unspecified
0.000 0.722 0.278
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.731 0.269
E03.5 Myxoedema coma
0.000 0.733 0.267
E03.4 Atrophy of thyroid (acquired)
0.000 0.733 0.267
E03.3 Postinfectious hypothyroidism
0.000 0.733 0.267
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.733 0.267
E04.8 Other specified non-toxic goitre
0.000 0.736 0.264
K51.8 Other ulcerative colitis
0.263 0.737 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.258 0.742 0.000
E23.2 Diabetes insipidus
0.000 0.747 0.253
E29 Testicular dysfunction
0.000 0.749 0.251
E06.4 Drug-induced thyroiditis
0.000 0.749 0.251
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.749 0.251
E06.1 Subacute thyroiditis
0.000 0.749 0.251
E06.0 Acute thyroiditis
0.000 0.749 0.251
E65-E68 Obesity and other hyperalimentation
0.000 0.749 0.251
E23.0 Hypopituitarism
0.000 0.751 0.249
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.754 0.246
E32 Diseases of thymus
0.000 0.754 0.246
E30 Disorders of puberty, not elsewhere classified
0.000 0.754 0.246
E25 Adrenogenital disorders
0.000 0.754 0.246
E44.1 Mild protein-energy malnutrition
0.000 0.756 0.243
E44.0 Moderate protein-energy malnutrition
0.000 0.756 0.243
E51 Thiamine deficiency
0.000 0.757 0.243
K51.5 Mucosal proctocolitis
0.243 0.757 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.760 0.240
E24.9 Cushing's syndrome, unspecified
0.000 0.766 0.234
E22 Hyperfunction of pituitary gland
0.000 0.771 0.229
E31 Polyglandular dysfunction
0.000 0.775 0.225
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.777 0.222
E63 Other nutritional deficiencies
0.000 0.777 0.222
E56 Other vitamin deficiencies
0.000 0.777 0.222
E50 Vitamin A deficiency
0.000 0.777 0.222
E60 Dietary zinc deficiency
0.000 0.777 0.222
E59 Dietary selenium deficiency
0.000 0.777 0.222
E54 Ascorbic acid deficiency
0.000 0.777 0.222
E52 Niacin deficiency [pellagra]
0.000 0.777 0.222
E28 Ovarian dysfunction
0.000 0.781 0.219
E24.2 Drug-induced Cushing's syndrome
0.000 0.788 0.212
E07.9 Disorder of thyroid, unspecified
0.000 0.789 0.211
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.789 0.211
E23.1 Drug-induced hypopituitarism
0.000 0.789 0.211
E83 Disorders of mineral metabolism
0.205 0.794 0.000
E20.8 Other hypoparathyroidism
0.000 0.797 0.203
E20.1 Pseudohypoparathyroidism
0.000 0.797 0.203
E20.0 Idiopathic hypoparathyroidism
0.000 0.797 0.203
E24.8 Other Cushing's syndrome
0.000 0.797 0.203
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.797 0.203
E24.3 Ectopic ACTH syndrome
0.000 0.797 0.203
E24.1 Nelson's syndrome
0.000 0.797 0.203
E24.0 Pituitary-dependent Cushing's disease
0.000 0.797 0.203
E26 Hyperaldosteronism
0.000 0.798 0.202
E06.5 Other chronic thyroiditis
0.000 0.798 0.202
E34 Other endocrine disorders
0.000 0.799 0.201
E11.3 With ophthalmic complications
0.000 0.800 0.200
E53 Deficiency of other B group vitamins
0.000 0.800 0.200
E23.7 Disorder of pituitary gland, unspecified
0.000 0.805 0.195
E51.2 Wernicke's encephalopathy
0.000 0.805 0.195
E58 Dietary calcium deficiency
0.000 0.810 0.190
E55 Vitamin D deficiency
0.000 0.814 0.186
E29.1 Testicular hypofunction
0.000 0.815 0.185
E23.6 Other disorders of pituitary gland
0.000 0.817 0.183
E29.9 Testicular dysfunction, unspecified
0.000 0.820 0.180
E29.8 Other testicular dysfunction
0.000 0.820 0.180
E29.0 Testicular hyperfunction
0.000 0.820 0.180
E67 Other hyperalimentation
0.000 0.820 0.180
E68 Sequelae of hyperalimentation
0.000 0.820 0.180
E22.0 Acromegaly and pituitary gigantism
0.000 0.821 0.179
E25.9 Adrenogenital disorder, unspecified
0.000 0.823 0.177
E25.8 Other adrenogenital disorders
0.000 0.823 0.177
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.823 0.177
E30.9 Disorder of puberty, unspecified
0.000 0.823 0.177
E30.8 Other disorders of puberty
0.000 0.823 0.177
E30.1 Precocious puberty
0.000 0.823 0.177
E30.0 Delayed puberty
0.000 0.823 0.177
E32.9 Disease of thymus, unspecified
0.000 0.823 0.177
E32.8 Other diseases of thymus
0.000 0.823 0.177
E32.1 Abscess of thymus
0.000 0.823 0.177
E32.0 Persistent hyperplasia of thymus
0.000 0.823 0.177
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.823 0.177
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.823 0.177
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.823 0.177
E51.9 Thiamine deficiency, unspecified
0.000 0.826 0.174
E51.8 Other manifestations of thiamine deficiency
0.000 0.826 0.174
E51.1 Beriberi
0.000 0.826 0.174
E04.0 Non-toxic diffuse goitre
0.001 0.828 0.172
E53.9 Vitamin B deficiency, unspecified
0.000 0.829 0.171
E28.3 Primary ovarian failure
0.000 0.831 0.169
E27 Other disorders of adrenal gland
0.000 0.835 0.165
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.836 0.164
E22.8 Other hyperfunction of pituitary gland
0.000 0.836 0.164
E31.9 Polyglandular dysfunction, unspecified
0.000 0.839 0.161
E31.8 Other polyglandular dysfunction
0.000 0.839 0.161
E31.1 Polyglandular hyperfunction
0.000 0.839 0.161
E50.9 Vitamin A deficiency, unspecified
0.000 0.840 0.160
E50.8 Other manifestations of vitamin A deficiency
0.000 0.840 0.160
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.840 0.160
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.840 0.160
E50.5 Vitamin A deficiency with night blindness
0.000 0.840 0.160
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.840 0.160
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.840 0.160
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.840 0.160
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.840 0.160
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.840 0.160
E56.9 Vitamin deficiency, unspecified
0.000 0.840 0.160
E56.8 Deficiency of other vitamins
0.000 0.840 0.160
E56.1 Deficiency of vitamin K
0.000 0.840 0.160
E56.0 Deficiency of vitamin E
0.000 0.840 0.160
E63.9 Nutritional deficiency, unspecified
0.000 0.840 0.160
E63.8 Other specified nutritional deficiencies
0.000 0.840 0.160
E63.1 Imbalance of constituents of food intake
0.000 0.840 0.160
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.840 0.160
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.840 0.160
E64.8 Sequelae of other nutritional deficiencies
0.000 0.840 0.160
E64.3 Sequelae of rickets
0.000 0.840 0.160
E64.2 Sequelae of vitamin C deficiency
0.000 0.840 0.160
E64.1 Sequelae of vitamin A deficiency
0.000 0.840 0.160
E64.0 Sequelae of protein-energy malnutrition
0.000 0.840 0.160
E28.9 Ovarian dysfunction, unspecified
0.000 0.843 0.157
E28.8 Other ovarian dysfunction
0.000 0.843 0.157
E28.1 Androgen excess
0.000 0.843 0.157
E28.0 Oestrogen excess
0.000 0.843 0.157
E83.3 Disorders of phosphorus metabolism
0.156 0.844 0.000
E22.1 Hyperprolactinaemia
0.000 0.846 0.154
E61 Deficiency of other nutrient elements
0.000 0.852 0.148
E83.9 Disorder of mineral metabolism, unspecified
0.147 0.852 0.000
E83.8 Other disorders of mineral metabolism
0.147 0.852 0.000
E83.2 Disorders of zinc metabolism
0.147 0.852 0.000
E83.0 Disorders of copper metabolism
0.147 0.852 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.855 0.145
E26.8 Other hyperaldosteronism
0.000 0.855 0.145
E26.1 Secondary hyperaldosteronism
0.000 0.855 0.145
E34.5 Androgen resistance syndrome
0.000 0.856 0.144
E34.4 Constitutional tall stature
0.000 0.856 0.144
E34.3 Short stature, not elsewhere classified
0.000 0.856 0.144
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.856 0.144
E34.1 Other hypersecretion of intestinal hormones
0.000 0.856 0.144
E53.1 Pyridoxine deficiency
0.000 0.856 0.143
E53.0 Riboflavin deficiency
0.000 0.856 0.143
E34.8 Other specified endocrine disorders
0.000 0.857 0.142
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.859 0.141
E65 Localised adiposity
0.000 0.859 0.141
E31.0 Autoimmune polyglandular failure
0.000 0.860 0.139
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.861 0.138
E34.9 Endocrine disorder, unspecified
0.000 0.866 0.134
E27.1 Primary adrenocortical insufficiency
0.000 0.866 0.134
E55.0 Rickets, active
0.000 0.867 0.133
E67.8 Other specified hyperalimentation
0.000 0.871 0.129
E67.3 Hypervitaminosis D
0.000 0.871 0.129
E67.2 Megavitamin-B6 syndrome
0.000 0.871 0.129
E67.1 Hypercarotenaemia
0.000 0.871 0.129
E67.0 Hypervitaminosis A
0.000 0.871 0.129
E83.4 Disorders of magnesium metabolism
0.123 0.877 0.000
E06.3 Autoimmune thyroiditis
0.000 0.878 0.122
E27.5 Adrenomedullary hyperfunction
0.000 0.882 0.118
E27.0 Other adrenocortical overactivity
0.000 0.882 0.118
E27.8 Other specified disorders of adrenal gland
0.000 0.883 0.117
E34.0 Carcinoid syndrome
0.000 0.884 0.116
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.889 0.111
E28.2 Polycystic ovarian syndrome
0.000 0.892 0.108
E21.3 Hyperparathyroidism, unspecified
0.000 0.893 0.107
E27.9 Disorder of adrenal gland, unspecified
0.000 0.893 0.107
E61.9 Deficiency of nutrient element, unspecified
0.000 0.893 0.106
E61.8 Deficiency of other specified nutrient elements
0.000 0.893 0.106
E61.7 Deficiency of multiple nutrient elements
0.000 0.893 0.106
E61.6 Vanadium deficiency
0.000 0.893 0.106
E61.5 Molybdenum deficiency
0.000 0.893 0.106
E61.4 Chromium deficiency
0.000 0.893 0.106
E61.3 Manganese deficiency
0.000 0.893 0.106
E61.0 Copper deficiency
0.000 0.893 0.106
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.895 0.105
E21.4 Other specified disorders of parathyroid gland
0.000 0.898 0.101
E26.0 Primary hyperaldosteronism
0.000 0.899 0.101
E21.2 Other hyperparathyroidism
0.000 0.903 0.096
E55.9 Vitamin D deficiency, unspecified
0.000 0.903 0.096
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.910 0.090
E61.2 Magnesium deficiency
0.000 0.913 0.087
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.915 0.085
E27.2 Addisonian crisis
0.000 0.915 0.085
E83.5 Disorders of calcium metabolism
0.069 0.931 0.000
E61.1 Iron deficiency
0.000 0.931 0.069
K50-K52 Noninfective enteritis and colitis
0.056 0.944 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.954 0.046
E53.8 Deficiency of other specified B group vitamins
0.000 0.954 0.046
K50 Crohn's disease [regional enteritis]
0.037 0.963 0.000
K90-K93 Other diseases of the digestive system
0.000 0.964 0.035
E11.9 Without complications
0.000 0.965 0.035
K50.9 Crohn's disease, unspecified
0.030 0.970 0.000
K50.0 Crohn's disease of small intestine
0.029 0.971 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.029 0.971 0.000
E04.2 Non-toxic multinodular goitre
0.001 0.972 0.027
E66 Obesity
0.000 0.973 0.027
C43.5 Malignant melanoma of trunk
0.000 0.973 0.027
E21.0 Primary hyperparathyroidism
0.000 0.974 0.026
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.974 0.025
K50.1 Crohn's disease of large intestine
0.024 0.976 0.000
H54.0 Blindness, both eyes
0.000 0.979 0.021
E66.1 Drug-induced obesity
0.000 0.980 0.019
K50.8 Other Crohn's disease
0.019 0.981 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.981 0.018
K93.1 Megacolon in Chagas' disease
0.000 0.981 0.018
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.981 0.018
K04.5 Chronic apical periodontitis
0.017 0.983 0.000
H54 Blindness and low vision
0.000 0.983 0.017
J38.7 Other diseases of larynx
0.016 0.984 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.016 0.984 0.000
J38.3 Other diseases of vocal cords
0.016 0.984 0.000
J38.4 Oedema of larynx
0.016 0.984 0.000
J38.2 Nodules of vocal cords
0.016 0.984 0.000
E66.0 Obesity due to excess calories
0.000 0.985 0.015
H54.9 Unspecified visual impairment (binocular)
0.000 0.985 0.015
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.985 0.015
H54.6 Unqualified visual loss, one eye
0.000 0.985 0.015
A08.4 Viral intestinal infection, unspecified
0.000 0.985 0.015
C43 Malignant melanoma of skin
0.000 0.986 0.014
J38.5 Laryngeal spasm
0.014 0.986 0.000
H54.5 Low vision, one eye
0.000 0.987 0.013
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.987 0.013
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.987 0.013
H54.7 Unspecified visual loss
0.000 0.988 0.012
I83 Varicose veins of lower extremities
0.012 0.988 0.000
H54.3 Unqualified visual loss, both eyes
0.000 0.988 0.012
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.988 0.012
V18.0 Driver injured in nontraffic accident
0.011 0.989 0.000
H54.4 Blindness, one eye
0.000 0.989 0.011
H54.1 Blindness, one eye, low vision, other eye
0.000 0.989 0.011
C43.9 Malignant melanoma of skin, unspecified
0.000 0.989 0.011
S64.0 Injury of ulnar nerve at wrist and hand level
0.011 0.989 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.010 0.989 0.000
C43.8 Overlapping malignant melanoma of skin
0.000 0.990 0.010
C43.0 Malignant melanoma of lip
0.000 0.990 0.010
H54.2 Low vision, both eyes
0.000 0.990 0.010
C43.4 Malignant melanoma of scalp and neck
0.000 0.990 0.010
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.990 0.010
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.990 0.010
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.991 0.009
J38.6 Stenosis of larynx
0.009 0.991 0.000
J38.1 Polyp of vocal cord and larynx
0.009 0.991 0.000
E66.8 Other obesity
0.000 0.991 0.009
I83.1 Varicose veins of lower extremities with inflammation
0.009 0.991 0.000
Z99.1 Dependence on respirator
0.000 0.991 0.009
M25.76 Osteophyte (Lower leg)
0.000 0.992 0.008
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.992 0.008
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.992 0.007
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.992 0.007
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.992 0.007
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.992 0.007
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.993 0.007
J38.0 Paralysis of vocal cords and larynx
0.007 0.993 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.993 0.007
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.993 0.007
I83.0 Varicose veins of lower extremities with ulcer
0.007 0.993 0.000
E70-E90 Metabolic disorders
0.001 0.994 0.005
K14.8 Other diseases of tongue
0.000 0.994 0.006
Z99.8 Dependence on other enabling machines and devices
0.000 0.994 0.006
J81 Pulmonary oedema
0.000 0.994 0.006
M25.71 Osteophyte (Shoulder region)
0.000 0.994 0.006
S64 Injury of nerves at wrist and hand level
0.006 0.994 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.006 0.994 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.994 0.006
N18.5 Chronic kidney disease, stage 5
0.000 0.995 0.005
E73 Lactose intolerance
0.001 0.995 0.005
S64.2 Injury of radial nerve at wrist and hand level
0.005 0.995 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.995 0.005
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.995 0.005
E79 Disorders of purine and pyrimidine metabolism
0.001 0.995 0.004
R01.1 Cardiac murmur, unspecified
0.000 0.995 0.005
S64.1 Injury of median nerve at wrist and hand level
0.005 0.995 0.000
H53-H54 Visual disturbances and blindness
0.000 0.995 0.005
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.995 0.005
E73.9 Lactose intolerance, unspecified
0.000 0.995 0.005
Z99.2 Dependence on renal dialysis
0.000 0.995 0.005
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.995 0.004
M25.7 Osteophyte
0.000 0.995 0.005
E74 Other disorders of carbohydrate metabolism
0.001 0.995 0.004
A08 Viral and other specified intestinal infections
0.000 0.995 0.005
E77 Disorders of glycoprotein metabolism
0.001 0.995 0.004
E76 Disorders of glycosaminoglycan metabolism
0.001 0.995 0.004
E72 Other disorders of amino-acid metabolism
0.001 0.995 0.004
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.995 0.004
E70 Disorders of aromatic amino-acid metabolism
0.001 0.995 0.004
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.995 0.004
E84 Cystic fibrosis
0.001 0.995 0.004
R01.0 Benign and innocent cardiac murmurs
0.000 0.995 0.005
K52 Other non-infective gastro-enteritis and colitis
0.005 0.995 0.000
H53.2 Diplopia
0.000 0.996 0.004
S64.4 Injury of digital nerve of other finger
0.004 0.996 0.000
V18.5 Passenger injured in traffic accident
0.004 0.996 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.004 0.996 0.000
S64.8 Injury of other nerves at wrist and hand level
0.004 0.996 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.004 0.996 0.000
V18.4 Driver injured in traffic accident
0.004 0.996 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.996 0.004
Z99.4 Dependence on artificial heart
0.000 0.996 0.004
Z99.0 Dependence on aspirator
0.000 0.996 0.004
N85.1 Endometrial adenomatous hyperplasia
0.000 0.996 0.004
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.996 0.004
Q23.1 Congenital insufficiency of aortic valve
0.004 0.996 0.000
Q23 Congenital malformations of aortic and mitral valves
0.004 0.996 0.000
V18.1 Passenger injured in nontraffic accident
0.004 0.996 0.000
X41.9 Unspecified place
0.004 0.996 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.000 0.996 0.004
N60.2 Fibroadenosis of breast
0.004 0.996 0.000
E73.8 Other lactose intolerance
0.001 0.996 0.004
E73.1 Secondary lactase deficiency
0.001 0.996 0.004
E73.0 Congenital lactase deficiency
0.001 0.996 0.004
S64.7 Injury of multiple nerves at wrist and hand level
0.004 0.996 0.000
M62.8 Other specified disorders of muscle
0.000 0.996 0.004
Q23.0 Congenital stenosis of aortic valve
0.004 0.996 0.000
L53.9 Erythematous condition, unspecified
0.004 0.996 0.000
V18.3 Person injured while boarding or alighting
0.004 0.996 0.000
R01 Cardiac murmurs and other cardiac sounds
0.000 0.996 0.004
N18.4 Chronic kidney disease, stage 4
0.000 0.996 0.004
A08.3 Other viral enteritis
0.000 0.996 0.004
M25.72 Osteophyte (Upper arm)
0.000 0.996 0.004
M25.79 Osteophyte (Site unspecified)
0.000 0.996 0.004
S42.10 Fracture of scapula (closed)
0.000 0.996 0.004
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.996 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.996 0.003
E79.1 Lesch-Nyhan syndrome
0.001 0.996 0.003
E75.5 Other lipid storage disorders
0.001 0.996 0.003
E85 Amyloidosis
0.001 0.996 0.003
D30.3 Bladder
0.004 0.996 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.004 0.996 0.000
Q21 Congenital malformations of cardiac septa
0.004 0.996 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.004 0.996 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.996 0.003
E75.6 Lipid storage disorder, unspecified
0.001 0.996 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.996 0.003
E75.3 Sphingolipidosis, unspecified
0.001 0.996 0.003
E75.1 Other gangliosidosis
0.001 0.996 0.003
E75.0 GM2 gangliosidosis
0.001 0.996 0.003
M25.70 Osteophyte (Multiple sites)
0.000 0.996 0.004
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.996 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.996 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.996 0.003
E74.2 Disorders of galactose metabolism
0.001 0.996 0.003
E74.1 Disorders of fructose metabolism
0.001 0.996 0.003
E74.0 Glycogen storage disease
0.001 0.996 0.003
A08.5 Other specified intestinal infections
0.000 0.996 0.003
A08.2 Adenoviral enteritis
0.000 0.996 0.003
A08.0 Rotaviral enteritis
0.000 0.996 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.996 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.996 0.003
E70.3 Albinism
0.001 0.996 0.003
E70.2 Disorders of tyrosine metabolism
0.001 0.996 0.003
E70.1 Other hyperphenylalaninaemias
0.001 0.996 0.003
E70.0 Classical phenylketonuria
0.001 0.996 0.003
E71.3 Disorders of fatty-acid metabolism
0.001 0.996 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.996 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.996 0.003
E71.0 Maple-syrup-urine disease
0.001 0.996 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.996 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.996 0.003
E72.5 Disorders of glycine metabolism
0.001 0.996 0.003
E72.4 Disorders of ornithine metabolism
0.001 0.996 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.996 0.003
E72.2 Disorders of urea cycle metabolism
0.001 0.996 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.996 0.003
E72.0 Disorders of amino-acid transport
0.001 0.996 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.996 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.996 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.996 0.003
E76.2 Other mucopolysaccharidoses
0.001 0.996 0.003
E76.1 Mucopolysaccharidosis, type II
0.001 0.996 0.003
E76.0 Mucopolysaccharidosis, type I
0.001 0.996 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.996 0.003
E77.8 Other disorders of glycoprotein metabolism
0.001 0.996 0.003
E77.1 Defects in glycoprotein degradation
0.001 0.996 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.996 0.003
Q20-Q28 Congenital malformations of the circulatory system
0.004 0.996 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.996 0.004
Q21.1 Atrial septal defect
0.004 0.996 0.000
E84.8 Cystic fibrosis with other manifestations
0.001 0.996 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.996 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.996 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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