TreeWAS – Variant ID: rs10836945

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.0 Calculus of kidney	0.000	0.971	0.029
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.022	0.978	0.000
N20 Calculus of kidney and ureter	0.000	0.978	0.022
I69 Sequelae of cerebrovascular disease	0.021	0.979	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.980	0.020
I60-I69 Cerebrovascular diseases	0.019	0.981	0.000
I69.3 Sequelae of cerebral infarction	0.019	0.981	0.000
H52.1 Myopia	0.000	0.982	0.018
I63 Cerebral infarction	0.018	0.982	0.000
I62 Other nontraumatic intracranial haemorrhage	0.017	0.982	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.017	0.983	0.000
N20.1 Calculus of ureter	0.000	0.983	0.017
I69.1 Sequelae of intracerebral haemorrhage	0.016	0.984	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.016	0.984	0.000
I67 Other cerebrovascular diseases	0.016	0.984	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.016	0.984	0.000
I60 Subarachnoid haemorrhage	0.016	0.984	0.000
I63.8 Other cerebral infarction	0.015	0.985	0.000
I67.9 Cerebrovascular disease, unspecified	0.015	0.985	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.015	0.985	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.015	0.985	0.000
N20.9 Urinary calculus, unspecified	0.000	0.985	0.014
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.014	0.985	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.014	0.986	0.000
I63.9 Cerebral infarction, unspecified	0.014	0.986	0.000
I61 Intracerebral haemorrhage	0.014	0.986	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.014	0.986	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.014	0.986	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.014	0.986	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.013	0.986	0.000
I67.1 Cerebral aneurysm, nonruptured	0.013	0.986	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.013	0.987	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.013	0.987	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.013	0.987	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.013	0.987	0.000
I60.8 Other subarachnoid haemorrhage	0.013	0.987	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.012	0.988	0.000
I65.2 Occlusion and stenosis of carotid artery	0.012	0.988	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.012	0.988	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.012	0.988	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.012	0.988	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.012	0.988	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.012	0.988	0.000
I62.1 Nontraumatic extradural haemorrhage	0.012	0.988	0.000
I65.1 Occlusion and stenosis of basilar artery	0.012	0.988	0.000
I61.8 Other intracerebral haemorrhage	0.012	0.988	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.012	0.988	0.000
I67.5 Moyamoya disease	0.011	0.988	0.000
I67.3 Progressive vascular leukoencephalopathy	0.011	0.988	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.011	0.988	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.011	0.988	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.011	0.989	0.000
N20-N23 Urolithiasis	0.000	0.989	0.011
I61.5 Intracerebral haemorrhage, intraventricular	0.011	0.989	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.011	0.989	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.011	0.989	0.000
I67.4 Hypertensive encephalopathy	0.011	0.989	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.011	0.989	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.011	0.989	0.000
I68.0 Cerebral amyloid angiopathy	0.010	0.989	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.011	0.989	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.010	0.989	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.010	0.989	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.010	0.989	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.010	0.989	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.010	0.989	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.010	0.989	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.010	0.989	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.010	0.990	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.010	0.990	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.010	0.990	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.010	0.990	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.010	0.990	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.010	0.990	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.010	0.990	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.010	0.990	0.000
N21 Calculus of lower urinary tract	0.000	0.990	0.010
I67.2 Cerebral atherosclerosis	0.010	0.990	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.010	0.990	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.010	0.990	0.000
H52 Disorders of refraction and accommodation	0.000	0.991	0.009
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.009	0.991	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.009	0.991	0.000
N21.0 Calculus in bladder	0.000	0.991	0.009
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.992	0.008
T85 Complications of other internal prosthetic devices, implants and grafts	0.008	0.992	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.992	0.008
N21.8 Other lower urinary tract calculus	0.000	0.992	0.008
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.007	0.993	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.993	0.007
N23 Unspecified renal colic	0.000	0.993	0.007
H52.6 Other disorders of refraction	0.000	0.993	0.007
H52.5 Disorders of accommodation	0.000	0.993	0.007
H52.2 Astigmatism	0.000	0.993	0.007
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.007	0.993	0.000
H52.4 Presbyopia	0.000	0.993	0.007
T85.2 Mechanical complication of intraocular lens	0.007	0.993	0.000
N21.1 Calculus in urethra	0.000	0.993	0.006
H52.0 Hypermetropia	0.000	0.993	0.006
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.006	0.993	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.006	0.994	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.006	0.994	0.000
I67.8 Other specified cerebrovascular diseases	0.006	0.994	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.994	0.006
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.994	0.006
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.994	0.006
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.006	0.994	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.005	0.994	0.001
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.006	0.994	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
T88.4 Failed or difficult intubation	0.006	0.994	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.006	0.994	0.000
D50.9 Iron deficiency anaemia, unspecified	0.005	0.995	0.000
T88.5 Other complications of anaesthesia	0.005	0.995	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.005	0.995	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.995	0.005
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.005	0.995	0.000
H50.0 Convergent concomitant strabismus	0.000	0.995	0.005
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
J06.9 Acute upper respiratory infection, unspecified	0.005	0.995	0.000
T88.9 Complication of surgical and medical care, unspecified	0.005	0.995	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.005	0.995	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.005	0.995	0.000
T88.0 Infection following immunisation	0.005	0.995	0.000
H50 Other strabismus	0.000	0.995	0.005
T88.3 Malignant hyperthermia due to anaesthesis	0.005	0.995	0.000
S82 Fracture of lower leg, including ankle	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
T88.2 Shock due to anaesthesia	0.004	0.995	0.000
S80-S89 Injuries to the knee and lower leg	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
S22.30 Fracture of rib (closed)	0.004	0.995	0.000
S27 Injury of other and unspecified intrathoracic organs	0.004	0.995	0.000
T42.4 Benzodiazepines	0.004	0.995	0.000
S82.8 Fractures of other parts of lower leg	0.004	0.996	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
S27.0 Traumatic pneumothorax	0.004	0.996	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.004	0.996	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.004	0.996	0.000
S82.2 Fracture of shaft of tibia	0.004	0.996	0.000
S20-S29 Injuries to the thorax	0.004	0.996	0.000
S82.6 Fracture of lateral malleolus	0.004	0.996	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
S86 Injury of muscle and tendon at lower leg level	0.004	0.996	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.004	0.996	0.000
S22.3 Fracture of rib	0.004	0.996	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.004	0.996	0.000
T86 Failure and rejection of transplanted organs and tissues	0.004	0.996	0.000
H50.6 Mechanical strabismus	0.000	0.996	0.004
K76 Other diseases of liver	0.004	0.996	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.004	0.996	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
S89 Other and unspecified injuries of lower leg	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.004	0.996	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.004	0.996	0.000
T83.2 Mechanical complication of graft of urinary organ	0.004	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.004	0.996	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.004	0.996	0.000
H51 Other disorders of binocular movement	0.000	0.996	0.004
H50.2 Vertical strabismus	0.000	0.996	0.004
S27.2 Traumatic heamopneumothorax	0.004	0.996	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.004	0.996	0.000
H50.8 Other specified strabismus	0.000	0.996	0.004
H49 Paralytic strabismus	0.000	0.996	0.004
K76.8 Other specified diseases of liver	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.004	0.996	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.004	0.996	0.000
S82.3 Fracture of lower end of tibia	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
S27.1 Traumatic haemothorax	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
H50.5 Heterophoria	0.000	0.996	0.004
S82.9 Fracture of lower leg, part unspecified	0.004	0.996	0.000
S82.0 Fracture of patella	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
T87 Complications peculiar to reattachment and amputation	0.003	0.996	0.000
H50.3 Intermittent heterotropia	0.000	0.996	0.003
S89.9 Unspecified injury of lower leg	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
S82.7 Multiple fractures of lower leg	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.004	0.996	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.996	0.004
S86.8 Injury of other muscles and tendons at lower leg level	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.996	0.000
S84 Injury of nerves at lower leg level	0.004	0.996	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.996	0.000
S81 Open wound of lower leg	0.004	0.996	0.000
S82.21 Fracture of shaft of tibia (open)	0.003	0.996	0.000
T46.1 Calcium-channel blockers	0.003	0.996	0.000
K76.9 Liver disease, unspecified	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
S88 Traumatic amputation of lower leg	0.003	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.996	0.000
T46.7 Peripheral vasodilators	0.003	0.996	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.003	0.996	0.000
S21 Open wound of thorax	0.003	0.996	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.003	0.996	0.000
H50.4 Other and unspecified heterotropia	0.000	0.996	0.003
T84.3 Mechanical complication of other bone devices, implants and grafts	0.003	0.996	0.000
S87 Crushing injury of lower leg	0.003	0.996	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.003	0.996	0.000
S27.9 Injury of unspecified intrathoracic organ	0.003	0.996	0.000
S27.7 Multiple injuries of intrathoracic organs	0.003	0.996	0.000
S27.6 Injury of pleura	0.003	0.996	0.000
S27.5 Injury of thoracic trachea	0.003	0.996	0.000
S27.4 Injury of bronchus	0.003	0.996	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.003	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.996	0.000
T42.0 Hydantoin derivatives	0.003	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.996	0.000
D50 Iron deficiency anaemia	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
K76.7 Hepatorenal syndrome	0.003	0.996	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.003	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.996	0.000
S82.86 Maisonneuve's fracture	0.003	0.997	0.000
S27.3 Other injuries of lung	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
S82.81 Fractures of other parts of lower leg (open)	0.003	0.997	0.000
H50.9 Strabismus, unspecified	0.000	0.997	0.003
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
S27.8 Injury of other specified intrathoracic organs	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
S26 Injury of heart	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.003	0.997	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.003	0.997	0.000
S25 Injury of blood vessels of thorax	0.003	0.997	0.000
H49.8 Other paralytic strabismus	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.003	0.997	0.001
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.003	0.997	0.000
S82.61 Fracture of lateral malleolus (open)	0.003	0.997	0.000
S86.0 Injury of Achilles tendon	0.003	0.997	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.003	0.997	0.000
T80.6 Other serum reactions	0.003	0.997	0.000
T80.5 Anaphylactic shock due to serum	0.003	0.997	0.000
T80.4 Rh incompatibility reaction	0.003	0.997	0.000
T80.3 ABO incompatibility reaction	0.003	0.997	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.003	0.997	0.000
K76.6 Portal hypertension	0.003	0.997	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.003	0.997	0.000
S24 Injury of nerves and spinal cord at thorax level	0.003	0.997	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.003	0.997	0.000
K74.3 Primary biliary cirrhosis	0.003	0.997	0.000
K76.1 Chronic passive congestion of liver	0.003	0.997	0.000
S22.5 Flail chest	0.003	0.997	0.000
T86.3 Heart-lung transplant failure and rejection	0.003	0.997	0.000
T86.2 Heart transplant failure and rejection	0.003	0.997	0.000
S89.8 Other specified injuries of lower leg	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
K76.5 Hepatic veno-occlusive disease	0.003	0.997	0.000
K76.4 Peliosis hepatis	0.003	0.997	0.000
K76.2 Central haemorrhagic necrosis of liver	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
K74.0 Hepatic fibrosis	0.003	0.997	0.000
H49.9 Paralytic strabismus, unspecified	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
S89.7 Multiple injuries of lower leg	0.003	0.997	0.000
S89.1 Other specified injuries of lower leg	0.003	0.997	0.000
S89.0 Multiple injuries of lower leg	0.003	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
H51.2 Internuclear ophthalmoplegia	0.000	0.997	0.003
K76.3 Infarction of liver	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
S22.1 Multiple fractures of thoracic spine	0.003	0.997	0.000
H51.1 Convergence insufficiency and excess	0.000	0.997	0.003
H51.0 Palsy of conjugate gaze	0.000	0.997	0.003
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T86.0 Bone-marrow transplant rejection	0.003	0.997	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.997	0.003
H51.8 Other specified disorders of binocular movement	0.000	0.997	0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
S50-S59 Injuries to the elbow and forearm	0.003	0.997	0.000
H49.4 Progressive external ophthalmoplegia	0.000	0.997	0.003
H49.3 Total (external) ophthalmoplegia	0.000	0.997	0.003
H51.9 Disorder of binocular movement, unspecified	0.000	0.997	0.003
S82.4 Fracture of fibula alone	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
S36 Injury of intra-abdominal organs	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
S82.1 Fracture of upper end of tibia	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T86.4 Liver transplant failure and rejection	0.003	0.997	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
S32.5 Fracture of pubis	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T87.5 Necrosis of amputation stump	0.003	0.997	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.997	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.003	0.997	0.000
G81.9 Hemiplegia, unspecified	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
T33-T35 Frostbite	0.003	0.997	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.003	0.997	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
S21.2 Open wound of back wall of thorax	0.003	0.997	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T87.2 Complications of other reattached body part	0.003	0.997	0.000
T87.1 Complications of reattached (part of) lower extremity	0.003	0.997	0.000
T87.0 Complications of reattached (part of) upper extremity	0.003	0.997	0.000
T81 Complications of procedures, not elsewhere classified	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.003	0.997	0.000
S21.1 Open wound of front wall of thorax	0.003	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S32.4 Fracture of acetabulum	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.003	0.997	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.003	0.997	0.000
S84.8 Injury of other nerves at lower leg level	0.003	0.997	0.000
S84.7 Injury of multiple nerves at lower leg level	0.003	0.997	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.003	0.997	0.000
S84.0 Injury of tibial nerve at lower leg level	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
S21.0 Open wound of breast	0.003	0.997	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.003	0.997	0.000
S85.8 Injury of other blood vessels at lower leg level	0.003	0.997	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.003	0.997	0.000
S85.5 Injury of popliteal vein	0.003	0.997	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.003	0.997	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.003	0.997	0.000
S85.2 Injury of peroneal artery	0.003	0.997	0.000
S85.0 Injury of popliteal artery	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.003	0.997	0.000
D50.1 Sideropenic dysphagia	0.003	0.997	0.000
S81.7 Multiple open wounds of lower leg	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.003	0.997	0.000
S21.8 Open wound of other parts of thorax	0.003	0.997	0.000
S21.7 Multiple open wounds of thoracic wall	0.003	0.997	0.000
S23.4 Sprain and strain of ribs and sternum	0.003	0.997	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.003	0.997	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.003	0.997	0.000
S88.0 Traumatic amputation at knee level	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
S82.01 Fracture of patella (open)	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
S83.7 Injury to multiple structures of knee	0.003	0.997	0.000
S87.0 Crushing injury of knee	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T87.3 Neuroma of amputation stump	0.003	0.997	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S21.9 Open wound of thorax, part unspecified	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.997	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.003	0.997	0.000
S20.2 Contusion of thorax	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.003	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.997	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S37 Injury of urinary and pelvic organs	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
K70-K77 Diseases of liver	0.003	0.997	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.003	0.997	0.000
S23.3 Sprain and strain of thoracic spine	0.003	0.997	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.003	0.997	0.000
S23.1 Dislocation of thoracic vertebra	0.003	0.997	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
S83.1 Dislocation of knee	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations