TreeWAS – Variant ID: rs10888499

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C15.9 Oesophagus, unspecified	0.000	0.888	0.112
C15 Malignant neoplasm of oesophagus	0.000	0.896	0.104
C15.5 Lower third of oesophagus	0.000	0.902	0.097
C15.4 Middle third of oesophagus	0.000	0.907	0.093
C15.3 Upper third of oesophagus	0.000	0.911	0.089
C15.8 Overlapping lesion of oesophagus	0.000	0.925	0.075
C15.2 Abdominal part of oesophagus	0.000	0.925	0.075
C15.0 Cervical part of oesophagus	0.000	0.927	0.073
C15.1 Thoracic part of oesophagus	0.000	0.928	0.072
N48.4 Impotence of organic origin	0.033	0.967	0.000
Z97.4 Presence of external hearing-aid	0.032	0.968	0.000
R25.2 Cramp and spasm	0.016	0.984	0.000
C71 Malignant neoplasm of brain	0.000	0.986	0.014
C71.8 Overlapping lesion of brain	0.000	0.986	0.014
C71.9 Brain, unspecified	0.000	0.986	0.014
C71.1 Frontal lobe	0.000	0.988	0.012
C71.0 Cerebrum, except lobes and ventricles	0.000	0.988	0.012
C71.2 Temporal lobe	0.000	0.988	0.012
C71.4 Occipital lobe	0.000	0.989	0.011
C71.3 Parietal lobe	0.000	0.990	0.010
C71.5 Cerebral ventricle	0.000	0.990	0.010
C71.7 Brain stem	0.000	0.990	0.010
R25 Abnormal involuntary movements	0.010	0.990	0.000
D13.1 Stomach	0.000	0.990	0.010
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.990	0.010
C71.6 Cerebellum	0.000	0.990	0.010
R25.1 Tremor, unspecified	0.010	0.990	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.009	0.991	0.000
N86 Erosion and ectropion of cervix uteri	0.008	0.992	0.000
D13.3 Other and unspecified parts of small intestine	0.000	0.992	0.008
R25.0 Abnormal head movements	0.007	0.992	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.993	0.007
N81.5 Vaginal enterocele	0.000	0.993	0.007
D13.0 Oesophagus	0.000	0.993	0.007
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.994	0.006
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.994	0.006
N87.0 Mild cervical dysplasia	0.006	0.994	0.000
Z52.4 Kidney donor	0.006	0.994	0.000
D13.4 Liver	0.000	0.994	0.006
C19 Malignant neoplasm of rectosigmoid junction	0.006	0.994	0.000
D13.2 Duodenum	0.000	0.994	0.006
D13.7 Endocrine pancreas	0.000	0.995	0.005
D13.9 Ill-defined sites within the digestive system	0.000	0.995	0.005
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.995	0.005
C69 Malignant neoplasm of eye and adnexa	0.000	0.995	0.005
M20.4 Other hammer toe(s) (acquired)	0.005	0.995	0.000
C69.9 Eye, unspecified	0.000	0.995	0.005
N48.8 Other specified disorders of penis	0.004	0.996	0.000
C50.4 Upper-outer quadrant of breast	0.004	0.996	0.000
D13.6 Pancreas	0.000	0.996	0.004
N48 Other disorders of penis	0.004	0.996	0.000
H73.8 Other specified disorders of tympanic membrane	0.004	0.996	0.000
C72.0 Spinal cord	0.000	0.996	0.004
C70 Malignant neoplasm of meninges	0.000	0.996	0.004
C69.2 Retina	0.000	0.996	0.004
D13.5 Extrahepatic bile ducts	0.000	0.996	0.004
C69.4 Ciliary body	0.000	0.996	0.004
M20.5 Other deformities of toe(s) (acquired)	0.004	0.996	0.000
C72.9 Central nervous system, unspecified	0.000	0.996	0.004
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.996	0.004
C72.5 Other and unspecified cranial nerves	0.000	0.996	0.004
C72.4 Acoustic nerve	0.000	0.996	0.004
C72.3 Optic nerve	0.000	0.996	0.004
C72.2 Olfactory nerve	0.000	0.996	0.004
C72.1 Cauda equina	0.000	0.996	0.004
C69.8 Overlapping lesion of eye and adnexa	0.000	0.996	0.004
C69.5 Lachrymal gland and duct	0.000	0.996	0.004
C69.1 Cornea	0.000	0.996	0.004
C69.6 Orbit	0.000	0.996	0.004
Z04.8 Examination and observation for other specified reasons	0.000	0.996	0.004
R25.3 Fasciculation	0.003	0.996	0.001
L20.9 Atopic dermatitis, unspecified	0.000	0.996	0.004
N48.2 Other inflammatory disorders of penis	0.004	0.996	0.000
C69.0 Conjunctiva	0.000	0.996	0.003
T39.0 Salicylates	0.003	0.997	0.000
H44.2 Degenerative myopia	0.000	0.997	0.003
C70.9 Meninges, unspecified	0.000	0.997	0.003
C70.1 Spinal meninges	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.003	0.997	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.997	0.003
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
N87.1 Moderate cervical dysplasia	0.003	0.997	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
C69.3 Choroid	0.000	0.997	0.003
N48.3 Priapism	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
N48.1 Balanoposthitis	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
C70.0 Cerebral meninges	0.000	0.997	0.002
R40.0 Somnolence	0.000	0.997	0.003
N48.5 Ulcer of penis	0.003	0.997	0.000
H52.2 Astigmatism	0.000	0.997	0.003
C02.9 Tongue, unspecified	0.000	0.997	0.003
Z93.5 Cystostomy status	0.000	0.997	0.002
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
G70.0 Myasthenia gravis	0.000	0.998	0.002
N87 Dysplasia of cervix uteri	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.002	0.998	0.000
C02.1 Border of tongue	0.000	0.998	0.002
H25.9 Senile cataract, unspecified	0.000	0.998	0.002
M24.01 Loose body in joint (Shoulder region)	0.000	0.998	0.002
C18.9 Colon, unspecified	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.002
M24.0 Loose body in joint	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.998	0.002
H73.1 Chronic myringitis	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
K62.7 Radiation proctitis	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
M79.69 Pain in limb (Site unspecified)	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
N26 Unspecified contracted kidney	0.002	0.998	0.000
N48.9 Disorder of penis, unspecified	0.002	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.000	0.998	0.002
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
N48.0 Leukoplakia of penis	0.002	0.998	0.000
N81.8 Other female genital prolapse	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
C18.6 Descending colon	0.000	0.998	0.002
D23.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.000	0.998	0.002
R58 Haemorrhage, not elsewhere classified	0.000	0.998	0.002
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.998	0.002
C02.4 Lingual tonsil	0.000	0.998	0.002
C02.0 Dorsal surface of tongue	0.000	0.998	0.002
O36.9 Maternal care for foetal problem, unspecified	0.000	0.998	0.002
M24.09 Loose body in joint (Site unspecified)	0.000	0.998	0.002
M24.08 Loose body in joint (Other)	0.000	0.998	0.002
M24.00 Loose body in joint (Multiple sites)	0.000	0.998	0.002
N21.0 Calculus in bladder	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
C10.9 Oropharynx, unspecified	0.000	0.998	0.002
I20.1 Angina pectoris with documented spasm	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.000	0.998	0.002
S01.9 Open wound of head, part unspecified	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.000	0.998	0.002
H43.3 Other vitreous opacities	0.000	0.998	0.002
K04.7 Periapical abscess without sinus	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.998	0.002
M24.26 Disorder of ligament (Lower leg)	0.000	0.998	0.002
C07 Malignant neoplasm of parotid gland	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.002	0.998	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
C02.2 Ventral surface of tongue	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
H73.0 Acute myringitis	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
H44 Disorders of globe	0.000	0.998	0.002
M79.62 Pain in limb (Upper arm)	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.998	0.002
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
N21.1 Calculus in urethra	0.000	0.998	0.002
H92.1 Otorrhoea	0.002	0.998	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.000	0.998	0.002
C05 Malignant neoplasm of palate	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
C05.1 Soft palate	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.000	0.998	0.002
L20 Atopic dermatitis	0.000	0.998	0.002
C05.9 Palate, unspecified	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.998	0.002
H44.5 Degenerated conditions of globe	0.000	0.998	0.001
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
G70 Myasthenia gravis and other myoneural disorders	0.000	0.998	0.002
T80.6 Other serum reactions	0.001	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.001	0.998	0.000
T80.4 Rh incompatibility reaction	0.001	0.998	0.000
T80.3 ABO incompatibility reaction	0.001	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.001	0.998	0.000
H44.9 Disorder of globe, unspecified	0.000	0.998	0.001
C05.0 Hard palate	0.000	0.998	0.001
C17.9 Small intestine, unspecified	0.001	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.998	0.001
N87.2 Severe cervical dysplasia, not elsewhere classified	0.001	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
C14.0 Pharynx, unspecified	0.000	0.998	0.001
H43.1 Vitreous haemorrhage	0.000	0.998	0.002
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.998	0.001
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.998	0.001
H44.3 Other degenerative disorders of globe	0.000	0.998	0.001
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.001	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.001
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.000	0.998	0.002
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.998	0.002
C05.8 Overlapping lesion of palate	0.000	0.998	0.001
C05.2 Uvula	0.000	0.998	0.001
C10.8 Overlapping lesion of oropharynx	0.000	0.998	0.001
C10.4 Branchial cleft	0.000	0.998	0.001
C10.3 Posterior wall of oropharynx	0.000	0.998	0.001
C10.2 Lateral wall of oropharynx	0.000	0.998	0.001
C10.1 Anterior surface of epiglottis	0.000	0.998	0.001
C10.0 Vallecula	0.000	0.998	0.001
C22.0 Liver cell carcinoma	0.000	0.998	0.001
H95.1 Other disorders following mastoidectomy	0.001	0.998	0.000
G12.2 Motor neuron disease	0.001	0.999	0.000
N80.1 Endometriosis of ovary	0.001	0.999	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.999	0.001
T80.2 Infections following infusion, transfusion and therapeutic injection	0.001	0.999	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.999	0.001
G71.1 Myotonic disorders	0.000	0.999	0.001
N92.3 Ovulation bleeding	0.001	0.999	0.000
C25.9 Pancreas, unspecified	0.001	0.999	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.001	0.999	0.000
H92.2 Otorrhagia	0.001	0.999	0.000
L20.0 Besnier's prurigo	0.000	0.999	0.001
Z81.8 Family history of other mental and behavioural disorders	0.000	0.999	0.001
Z90.0 Acquired absence of part of head and neck	0.000	0.999	0.001
C01 Malignant neoplasm of base of tongue	0.000	0.999	0.001
N21 Calculus of lower urinary tract	0.000	0.999	0.001
G70.2 Congenital and developmental myasthenia	0.000	0.999	0.001
G70.1 Toxic myoneural disorders	0.000	0.999	0.001
H44.1 Other endophthalmitis	0.000	0.999	0.001
L20.8 Other atopic dermatitis	0.000	0.999	0.001
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.001	0.999	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.000	0.999	0.001
G70.9 Myoneural disorder, unspecified	0.000	0.999	0.001
H44.8 Other disorders of globe	0.000	0.999	0.001
H44.4 Hypotony of eye	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
O40 Polyhydramnios	0.001	0.999	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
F42 Obsessive-compulsive disorder	0.001	0.999	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.999	0.001
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.999	0.001
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.999	0.001
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.999	0.001
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.999	0.001
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.999	0.001
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.999	0.001
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.999	0.001
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.999	0.001
M24.24 Disorder of ligament (Hand)	0.000	0.999	0.001
C14.2 Waldeyer's ring	0.000	0.999	0.001
C25.0 Head of pancreas	0.001	0.999	0.000
G70.8 Other specified myoneural disorders	0.000	0.999	0.001
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.999	0.001
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.001	0.999	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.001	0.999	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.001	0.999	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.001	0.999	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.001	0.999	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.001	0.999	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.001	0.999	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.999	0.001
D63.8 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
Z00.5 Examination of potential donor of organ and tissue	0.001	0.999	0.000
C22.9 Liver, unspecified	0.000	0.999	0.001
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
K59.3 Megacolon, not elsewhere classified	0.000	0.999	0.001
M24.2 Disorder of ligament	0.000	0.999	0.001
X41.9 Unspecified place	0.001	0.999	0.000
G11 Hereditary ataxia	0.001	0.999	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.001	0.999	0.000
M79.63 Pain in limb (Forearm)	0.001	0.999	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.001	0.999	0.000
G11.1 Early-onset cerebellar ataxia	0.001	0.999	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.999	0.001
I09.9 Rheumatic heart disease, unspecified	0.001	0.999	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.999	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.999	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.999	0.001
E23.7 Disorder of pituitary gland, unspecified	0.001	0.999	0.000
N21.8 Other lower urinary tract calculus	0.000	0.999	0.001
R44.3 Hallucinations, unspecified	0.000	0.999	0.001
R90.0 Intracranial space-occupying lesion	0.000	0.999	0.001
H43 Disorders of vitreous body	0.000	0.999	0.001
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.999	0.001
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.999	0.001
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.999	0.001
T47.4 Other laxatives	0.001	0.999	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.001	0.999	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.999	0.001
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.999	0.001
M91.20 Coxa plana-Mult sites	0.000	0.999	0.001
F42.2 Mixed obsessional thoughts and acts	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.999	0.001
C13 Malignant neoplasm of hypopharynx	0.000	0.999	0.001
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
F42.8 Other obsessive-compulsive disorders	0.001	0.999	0.000
G96.0 Cerebrospinal fluid leak	0.001	0.999	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.001	0.999	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.999	0.001
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.999	0.001
S61.8 Open wound of other parts of wrist and hand	0.000	0.999	0.001
C12 Malignant neoplasm of pyriform sinus	0.000	0.999	0.001
M24 Other specific joint derangements	0.000	0.999	0.001
Z52 Donors of organs and tissues	0.001	0.999	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.999	0.001
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.999	0.001
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.999	0.001
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.999	0.001
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.999	0.001
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.999	0.001
M25.71 Osteophyte (Shoulder region)	0.000	0.999	0.001
M24.5 Contracture of joint	0.000	0.999	0.001
R07.1 Chest pain on breathing	0.000	0.999	0.001
M24.29 Disorder of ligament (Site unspecified)	0.000	0.999	0.001
M24.22 Disorder of ligament (Upper arm)	0.000	0.999	0.001
M24.20 Disorder of ligament (Multiple sites)	0.000	0.999	0.001
M24.51 Contracture of joint (Shoulder region)	0.000	0.999	0.001
C08.8 Overlapping lesion of major salivary glands	0.000	0.999	0.001
C08.1 Sublingual gland	0.000	0.999	0.001
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000
G11.2 Late-onset cerebellar ataxia	0.001	0.999	0.000
G11.0 Congenital nonprogressive ataxia	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
T47.2 Stimulant laxatives	0.001	0.999	0.000
C03 Malignant neoplasm of gum	0.000	0.999	0.001
C08.9 Major salivary gland, unspecified	0.000	0.999	0.001
H43.0 Vitreous prolapse	0.000	0.999	0.001
L89.9 Decubitus ulcer and pressure area, unspecified	0.001	0.999	0.000
C11 Malignant neoplasm of nasopharynx	0.000	0.999	0.001
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.999	0.000
C08.0 Submandibular gland	0.000	0.999	0.001
D38.1 Trachea, bronchus and lung	0.000	0.999	0.001
M24.9 Joint derangement, unspecified	0.000	0.999	0.001
M24.7 Protrusio acetabuli	0.000	0.999	0.001
S83.2 Tear of meniscus, current	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
C13.8 Overlapping lesion of hypopharynx	0.000	0.999	0.001
C13.2 Posterior wall of hypopharynx	0.000	0.999	0.001
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.000	0.999	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000
Z52.9 Donor of unspecified organ or tissue	0.001	0.999	0.000
Z52.7 Heart donor	0.001	0.999	0.000
Z52.6 Liver donor	0.001	0.999	0.000
Z52.5 Cornea donor	0.001	0.999	0.000
Z52.1 Skin donor	0.001	0.999	0.000
G12 Spinal muscular atrophy and related syndromes	0.001	0.999	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.999	0.001
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.999	0.001
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.999	0.001
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
M24.59 Contracture of joint (Site unspecified)	0.000	0.999	0.001
M24.58 Contracture of joint (Other)	0.000	0.999	0.001
M24.57 Contracture of joint (Ankle and foot)	0.000	0.999	0.001
M24.53 Contracture of joint (Forearm)	0.000	0.999	0.001
M24.50 Contracture of joint (Multiple sites)	0.000	0.999	0.001
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.999	0.001
C13.0 Postcricoid region	0.000	0.999	0.001
C25.7 Other parts of pancreas	0.001	0.999	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
H44.0 Purulent endophthalmitis	0.000	0.999	0.001
H52.7 Disorder of refraction, unspecified	0.000	0.999	0.001
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
C25 Malignant neoplasm of pancreas	0.001	0.999	0.000
Z97 Presence of other devices	0.001	0.999	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.999	0.001
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.999	0.001
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C03.0 Upper gum	0.000	0.999	0.001
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.999	0.000
G96.8 Other specified disorders of central nervous system	0.001	0.999	0.000
M24.6 Ankylosis of joint	0.000	0.999	0.001
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.999	0.001
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.999	0.001
G71 Primary disorders of muscles	0.000	0.999	0.001
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.001	0.999	0.000
M21.27 Flexion deformity (Ankle and foot)	0.001	0.999	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.999	0.001
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.999	0.001
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.999	0.001
M24.98 Joint derangement, unspecified (Other)	0.000	0.999	0.001
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.999	0.001
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M24.94 Joint derangement, unspecified (Hand)	0.000	0.999	0.001
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.999	0.001
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.999	0.001
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.999	0.001
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.999	0.001
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C11.8 Overlapping lesion of nasopharynx	0.000	0.999	0.001
C11.3 Anterior wall of nasopharynx	0.000	0.999	0.001
C11.2 Lateral wall of nasopharynx	0.000	0.999	0.001
C11.1 Posterior wall of nasopharynx	0.000	0.999	0.001
C11.0 Superior wall of nasopharynx	0.000	0.999	0.001
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.001	0.999	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.000	0.999	0.001
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M24.56 Contracture of joint (Lower leg)	0.000	0.999	0.001
M24.79 Protrusio acetabuli-Site unspec	0.000	0.999	0.001
M24.78 Protrusio acetabuli-Other	0.000	0.999	0.001
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.999	0.001
M24.76 Protrusio acetabuli-Lower leg	0.000	0.999	0.001
M24.74 Protrusio acetabuli-Hand	0.000	0.999	0.001
M24.73 Protrusio acetabuli-Forearm	0.000	0.999	0.001
M24.72 Protrusio acetabuli-Upper arm	0.000	0.999	0.001
M24.71 Protrusio acetabuli-Shldr region	0.000	0.999	0.001
M24.70 Protrusio acetabuli-Mult sites	0.000	0.999	0.001
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.999	0.001
C03.9 Gum, unspecified	0.000	0.999	0.001
C62.9 Testis, unspecified	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.999	0.000
G12.9 Spinal muscular atrophy, unspecified	0.001	0.999	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.001	0.999	0.000
G12.1 Other inherited spinal muscular atrophy	0.001	0.999	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.999	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.999	0.001
R09.1 Pleurisy	0.000	0.999	0.001
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
T09.3 Injury of spinal cord, level unspecified	0.000	0.999	0.001
C04 Malignant neoplasm of floor of mouth	0.000	0.999	0.001
C00 Malignant neoplasm of lip	0.000	0.999	0.001
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.001	0.999	0.000
M24.52 Contracture of joint (Upper arm)	0.000	0.999	0.001
M25.86 Other specified joint disorders (Lower leg)	0.000	0.999	0.001
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.000	0.999	0.001
C06.1 Vestibule of mouth	0.000	0.999	0.001
C13.9 Hypopharynx, unspecified	0.000	0.999	0.001
G71.9 Primary disorder of muscle, unspecified	0.000	0.999	0.001
G71.8 Other primary disorders of muscles	0.000	0.999	0.001
G71.2 Congenital myopathies	0.000	0.999	0.001
H43.9 Disorder of vitreous body, unspecified	0.000	0.999	0.001
H43.2 Crystalline deposits in vitreous body	0.000	0.999	0.001
Y45.0 Opioids and related analgesics	0.001	0.999	0.000
Z52.8 Donor of other organs and tissues	0.001	0.999	0.000
G10 Huntington's disease	0.001	0.999	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.999	0.001
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.999	0.001
M24.68 Ankylosis of joint (Other)	0.000	0.999	0.001
M24.63 Ankylosis of joint (Forearm)	0.000	0.999	0.001
M24.62 Ankylosis of joint (Upper arm)	0.000	0.999	0.001
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.999	0.001
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.999	0.001
C22.7 Other specified carcinomas of liver	0.000	0.999	0.001
C22.4 Other sarcomas of liver	0.000	0.999	0.001
C22.3 Angiosarcoma of liver	0.000	0.999	0.001
C22.2 Hepatoblastoma	0.000	0.999	0.001
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.999	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.999	0.001
M25.7 Osteophyte	0.000	0.999	0.001
N31.8 Other neuromuscular dysfunction of bladder	0.001	0.999	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.999	0.001
W44.0 Home	0.001	0.999	0.000
Y60.0 During surgical operation	0.000	0.999	0.001
M24.21 Disorder of ligament (Shoulder region)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations