TreeWAS – Variant ID: rs10892562

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001	0.000
I20 Angina pectoris	0.997	0.003	0.000
I20.9 Angina pectoris, unspecified	0.992	0.008	0.000
I22 Subsequent myocardial infarction	0.986	0.014	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.981	0.019	0.000
I20.0 Unstable angina	0.979	0.021	0.000
I25.2 Old myocardial infarction	0.978	0.022	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.943	0.057	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.943	0.057	0.000
I25.5 Ischaemic cardiomyopathy	0.920	0.080	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.865	0.135	0.000
I23 Certain current complications following acute myocardial infarction	0.857	0.143	0.000
I23.8 Other current complications following acute myocardial infarction	0.755	0.245	0.000
I25.6 Silent myocardial ischaemia	0.744	0.256	0.000
I25.3 Aneurysm of heart	0.727	0.273	0.000
I22.8 Subsequent myocardial infarction of other sites	0.681	0.319	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.614	0.385	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.614	0.385	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.614	0.385	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.614	0.385	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.614	0.385	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.614	0.385	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.614	0.385	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.608	0.392	0.000
I25.4 Coronary artery aneurysm	0.579	0.421	0.000
I20.8 Other forms of angina pectoris	0.545	0.455	0.000
I21 Acute myocardial infarction	0.520	0.480	0.000
I21.4 Acute subendocardial myocardial infarction	0.485	0.515	0.000
I20.1 Angina pectoris with documented spasm	0.434	0.566	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.415	0.585	0.000
I24 Other acute ischaemic heart diseases	0.407	0.593	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.373	0.627	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.359	0.641	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.358	0.642	0.000
I24.1 Dressler's syndrome	0.313	0.687	0.000
I24.8 Other forms of acute ischaemic heart disease	0.253	0.747	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.249	0.751	0.000
I21.9 Acute myocardial infarction, unspecified	0.228	0.772	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.816	0.184
E27 Other disorders of adrenal gland	0.000	0.817	0.183
E27.1 Primary adrenocortical insufficiency	0.000	0.823	0.177
H40.9 Glaucoma, unspecified	0.169	0.831	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.166	0.834	0.000
H40 Glaucoma	0.159	0.841	0.000
E27.2 Addisonian crisis	0.000	0.844	0.156
H40.0 Glaucoma suspect	0.154	0.846	0.000
H40.2 Primary angle-closure glaucoma	0.152	0.848	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.850	0.150
E20-E35 Disorders of other endocrine glands	0.000	0.855	0.145
I21.0 Acute transmural myocardial infarction of anterior wall	0.138	0.862	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.868	0.132
E27.5 Adrenomedullary hyperfunction	0.000	0.868	0.131
E27.0 Other adrenocortical overactivity	0.000	0.868	0.131
E23 Hypofunction and other disorders of pituitary gland	0.000	0.869	0.131
E20 Hypoparathyroidism	0.000	0.871	0.129
E24 Cushing's syndrome	0.000	0.874	0.126
I24.9 Acute ischaemic heart disease, unspecified	0.124	0.876	0.000
E29 Testicular dysfunction	0.000	0.878	0.122
E20.9 Hypoparathyroidism, unspecified	0.000	0.882	0.118
E23.0 Hypopituitarism	0.000	0.883	0.117
E27.8 Other specified disorders of adrenal gland	0.000	0.883	0.116
H40.8 Other glaucoma	0.114	0.886	0.000
H40.6 Glaucoma secondary to drugs	0.114	0.886	0.000
E26 Hyperaldosteronism	0.000	0.887	0.113
H40.4 Glaucoma secondary to eye inflammation	0.108	0.892	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.893	0.107
H40.1 Primary open-angle glaucoma	0.107	0.893	0.000
E29.1 Testicular hypofunction	0.000	0.895	0.105
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.896	0.104
E32 Diseases of thymus	0.000	0.896	0.104
E31 Polyglandular dysfunction	0.000	0.896	0.104
E30 Disorders of puberty, not elsewhere classified	0.000	0.896	0.104
E34 Other endocrine disorders	0.000	0.897	0.103
E23.6 Other disorders of pituitary gland	0.000	0.898	0.102
E23.7 Disorder of pituitary gland, unspecified	0.000	0.901	0.099
E24.9 Cushing's syndrome, unspecified	0.000	0.902	0.098
E25 Adrenogenital disorders	0.000	0.902	0.098
H40.3 Glaucoma secondary to eye trauma	0.096	0.903	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.906	0.094
E23.1 Drug-induced hypopituitarism	0.000	0.906	0.094
E24.2 Drug-induced Cushing's syndrome	0.000	0.906	0.093
E20.8 Other hypoparathyroidism	0.000	0.907	0.093
E20.1 Pseudohypoparathyroidism	0.000	0.907	0.093
E20.0 Idiopathic hypoparathyroidism	0.000	0.907	0.093
E24.8 Other Cushing's syndrome	0.000	0.909	0.091
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.909	0.091
E24.3 Ectopic ACTH syndrome	0.000	0.909	0.091
E24.1 Nelson's syndrome	0.000	0.909	0.091
E26.0 Primary hyperaldosteronism	0.000	0.910	0.090
E23.2 Diabetes insipidus	0.000	0.910	0.090
E29.9 Testicular dysfunction, unspecified	0.000	0.912	0.087
E29.8 Other testicular dysfunction	0.000	0.912	0.087
E29.0 Testicular hyperfunction	0.000	0.912	0.087
E22 Hyperfunction of pituitary gland	0.000	0.914	0.085
E26.8 Other hyperaldosteronism	0.000	0.919	0.081
E26.1 Secondary hyperaldosteronism	0.000	0.919	0.081
E26.9 Hyperaldosteronism, unspecified	0.000	0.920	0.080
E28 Ovarian dysfunction	0.000	0.921	0.079
E34.9 Endocrine disorder, unspecified	0.000	0.922	0.077
C67.9 Bladder, unspecified	0.076	0.924	0.000
E34.8 Other specified endocrine disorders	0.000	0.924	0.076
E30.9 Disorder of puberty, unspecified	0.000	0.925	0.075
E30.8 Other disorders of puberty	0.000	0.925	0.075
E30.1 Precocious puberty	0.000	0.925	0.075
E30.0 Delayed puberty	0.000	0.925	0.075
E31.9 Polyglandular dysfunction, unspecified	0.000	0.925	0.075
E31.8 Other polyglandular dysfunction	0.000	0.925	0.075
E31.1 Polyglandular hyperfunction	0.000	0.925	0.075
E31.0 Autoimmune polyglandular failure	0.000	0.925	0.075
E32.9 Disease of thymus, unspecified	0.000	0.925	0.075
E32.8 Other diseases of thymus	0.000	0.925	0.075
E32.1 Abscess of thymus	0.000	0.925	0.075
E32.0 Persistent hyperplasia of thymus	0.000	0.925	0.075
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.925	0.075
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.925	0.075
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.925	0.075
E34.5 Androgen resistance syndrome	0.000	0.926	0.074
E34.4 Constitutional tall stature	0.000	0.926	0.074
E34.3 Short stature, not elsewhere classified	0.000	0.926	0.074
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.926	0.074
E34.1 Other hypersecretion of intestinal hormones	0.000	0.926	0.074
C67 Malignant neoplasm of bladder	0.071	0.929	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.929	0.070
E25.8 Other adrenogenital disorders	0.000	0.929	0.070
C67.1 Dome of bladder	0.069	0.931	0.000
C67.3 Anterior wall of bladder	0.068	0.932	0.000
E34.0 Carcinoid syndrome	0.000	0.933	0.067
H40-H42 Glaucoma	0.066	0.934	0.000
E22.1 Hyperprolactinaemia	0.000	0.934	0.065
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.936	0.064
C67.0 Trigone of bladder	0.063	0.937	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.938	0.062
H40.5 Glaucoma secondary to other eye disorders	0.062	0.938	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.938	0.061
E22.8 Other hyperfunction of pituitary gland	0.000	0.938	0.061
E28.9 Ovarian dysfunction, unspecified	0.000	0.943	0.057
E28.8 Other ovarian dysfunction	0.000	0.943	0.057
E28.1 Androgen excess	0.000	0.943	0.057
E28.0 Oestrogen excess	0.000	0.943	0.057
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.946	0.054
C67.7 Urachus	0.051	0.949	0.000
C67.5 Bladder neck	0.051	0.949	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.950	0.050
C67.2 Lateral wall of bladder	0.050	0.950	0.000
H42 Glaucoma in diseases classified elsewhere	0.048	0.952	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.957	0.043
E28.3 Primary ovarian failure	0.000	0.957	0.042
C67.8 Overlapping lesion of bladder	0.040	0.960	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.961	0.039
C67.4 Posterior wall of bladder	0.038	0.962	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.964	0.036
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.036	0.964	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.034	0.965	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.034	0.965	0.000
C67.6 Ureteric orifice	0.034	0.966	0.000
E21.2 Other hyperparathyroidism	0.000	0.966	0.033
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.033	0.967	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.968	0.032
E21.0 Primary hyperparathyroidism	0.000	0.974	0.026
E21.3 Hyperparathyroidism, unspecified	0.000	0.978	0.022
C64-C68 Malignant neoplasms of urinary tract	0.021	0.979	0.000
I42.9 Cardiomyopathy, unspecified	0.020	0.980	0.000
I42.0 Dilated cardiomyopathy	0.019	0.981	0.000
I42 Cardiomyopathy	0.018	0.982	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.017	0.983	0.000
I08.0 Disorders of both mitral and aortic valves	0.017	0.983	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.016	0.984	0.000
Chapter IX Diseases of the circulatory system	0.016	0.984	0.000
I08.8 Other multiple valve diseases	0.016	0.984	0.000
I08 Multiple valve diseases	0.015	0.985	0.000
I42.6 Alcoholic cardiomyopathy	0.015	0.985	0.000
I05-I09 Chronic rheumatic heart diseases	0.015	0.985	0.000
I30-I52 Other forms of heart disease	0.015	0.985	0.000
C68.0 Urethra	0.014	0.986	0.000
I42.5 Other restrictive cardiomyopathy	0.014	0.986	0.000
I33 Acute and subacute endocarditis	0.014	0.986	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.013	0.987	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.013	0.987	0.000
I44.2 Atrioventricular block, complete	0.013	0.987	0.000
I42.4 Endocardial fibroelastosis	0.013	0.987	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.013	0.987	0.000
I44 Atrioventricular and left bundle-branch block	0.013	0.987	0.000
C68.9 Urinary organ, unspecified	0.012	0.987	0.000
C68.8 Overlapping lesion of urinary organs	0.012	0.987	0.000
C68.1 Paraurethral glands	0.012	0.987	0.000
I33.0 Acute and subacute infective endocarditis	0.013	0.987	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.013	0.987	0.000
I47 Paroxysmal tachycardia	0.012	0.988	0.000
I44.3 Other and unspecified atrioventricular block	0.012	0.988	0.000
C66 Malignant neoplasm of ureter	0.012	0.988	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.012	0.988	0.000
Z87.8 Personal history of other specified conditions	0.012	0.988	0.000
I36 Nonrheumatic tricuspid valve disorders	0.012	0.988	0.000
I46 Cardiac arrest	0.012	0.988	0.000
I47.0 Reentry ventricular arrhythmia	0.012	0.988	0.000
I38 Endocarditis, valve unspecified	0.012	0.988	0.000
I30 Acute pericarditis	0.012	0.988	0.000
I08.9 Multiple valve disease, unspecified	0.011	0.988	0.000
C65 Malignant neoplasm of renal pelvis	0.011	0.988	0.000
I46.0 Cardiac arrest with successful resuscitation	0.011	0.989	0.000
I06 Rheumatic aortic valve diseases	0.011	0.989	0.000
I09 Other rheumatic heart diseases	0.011	0.989	0.000
I33.9 Acute endocarditis, unspecified	0.011	0.989	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.011	0.989	0.000
I52 Other heart disorders in diseases classified elsewhere	0.011	0.989	0.000
I48 Atrial fibrillation and flutter	0.011	0.989	0.000
I41 Myocarditis in diseases classified elsewhere	0.011	0.989	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.011	0.989	0.000
I32 Pericarditis in diseases classified elsewhere	0.011	0.989	0.000
I30.9 Acute pericarditis, unspecified	0.011	0.989	0.000
I00-I02 Acute rheumatic fever	0.010	0.989	0.000
I44.4 Left anterior fascicular block	0.010	0.989	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.010	0.990	0.000
I37 Pulmonary valve disorders	0.010	0.990	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.010	0.990	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.010	0.990	0.000
I05 Rheumatic mitral valve diseases	0.010	0.990	0.000
I99 Other and unspecified disorders of circulatory system	0.010	0.990	0.000
I42.8 Other cardiomyopathies	0.010	0.990	0.000
I40 Acute myocarditis	0.010	0.990	0.000
I50 Heart failure	0.010	0.990	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.010	0.990	0.000
Z88.2 Personal history of allergy to sulphonamides	0.010	0.990	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.010	0.990	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.010	0.990	0.000
I46.1 Sudden cardiac death, so described	0.010	0.990	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.010	0.990	0.000
I35 Nonrheumatic aortic valve disorders	0.009	0.991	0.000
I44.5 Left posterior fascicular block	0.009	0.991	0.000
I47.2 Ventricular tachycardia	0.009	0.991	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.009	0.991	0.000
B34.9 Viral infection, unspecified	0.009	0.991	0.000
I05.0 Mitral stenosis	0.009	0.991	0.000
N89.5 Stricture and atresia of vagina	0.000	0.991	0.009
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.009	0.991	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.009	0.991	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.009	0.991	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.009	0.991	0.000
I05.1 Rheumatic mitral insufficiency	0.009	0.991	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.008	0.991	0.000
I30.8 Other forms of acute pericarditis	0.008	0.991	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.008	0.991	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.008	0.992	0.000
K26.7 Chronic without haemorrhage or perforation	0.008	0.992	0.000
I06.8 Other rheumatic aortic valve diseases	0.008	0.992	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.008	0.992	0.000
I06.1 Rheumatic aortic insufficiency	0.008	0.992	0.000
I35.9 Aortic valve disorder, unspecified	0.008	0.992	0.000
I09.9 Rheumatic heart disease, unspecified	0.008	0.992	0.000
I09.8 Other specified rheumatic heart diseases	0.008	0.992	0.000
I09.2 Chronic rheumatic pericarditis	0.008	0.992	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.008	0.992	0.000
I09.0 Rheumatic myocarditis	0.008	0.992	0.000
I50.1 Left ventricular failure	0.008	0.992	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.008	0.992	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.008	0.992	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.008	0.992	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.008	0.992	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.008	0.992	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.008	0.992	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.008	0.992	0.000
I48.4 Atypical atrial flutter	0.008	0.992	0.000
I48.3 Typical atrial flutter	0.008	0.992	0.000
I48.2 Chronic atrial fibrillation	0.008	0.992	0.000
I48.1 Persistent atrial fibrillation	0.008	0.992	0.000
I48.0 Paroxysmal atrial fibrillation	0.008	0.992	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.008	0.992	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.008	0.992	0.000
I40.9 Acute myocarditis, unspecified	0.008	0.992	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.008	0.992	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.008	0.992	0.000
I02 Rheumatic chorea	0.008	0.992	0.000
I01 Rheumatic fever with heart involvement	0.008	0.992	0.000
I07 Rheumatic tricuspid valve diseases	0.008	0.992	0.000
I06.0 Rheumatic aortic stenosis	0.008	0.992	0.000
I44.7 Left bundle-branch block, unspecified	0.008	0.992	0.000
I35.8 Other aortic valve disorders	0.008	0.992	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.007	0.992	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.007	0.992	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I37.9 Pulmonary valve disorder, unspecified	0.007	0.992	0.000
I37.8 Other pulmonary valve disorders	0.007	0.992	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.007	0.992	0.000
I37.0 Pulmonary valve stenosis	0.007	0.992	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.007	0.992	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I98.0 Cardiovascular syphilis	0.007	0.992	0.000
I05.8 Other mitral valve diseases	0.007	0.992	0.000
I40.8 Other acute myocarditis	0.007	0.992	0.000
I40.1 Isolated myocarditis	0.007	0.992	0.000
I49 Other cardiac arrhythmias	0.008	0.992	0.000
I44.6 Other and unspecified fascicular block	0.007	0.993	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.007	0.993	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.007	0.993	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.007	0.993	0.000
I50.9 Heart failure, unspecified	0.007	0.993	0.000
I97.0 Postcardiotomy syndrome	0.007	0.993	0.000
I37.1 Pulmonary valve insufficiency	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
Z39.1 Care and examination of lactating mother	0.007	0.993	0.000
I35.1 Aortic (valve) insufficiency	0.007	0.993	0.000
I49.1 Atrial premature depolarisation	0.007	0.993	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.007	0.993	0.000
I00 Rheumatic fever without mention of heart involvement	0.006	0.993	0.000
I95 Hypotension	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
I49.0 Ventricular fibrillation and flutter	0.007	0.993	0.000
I40.0 Infective myocarditis	0.006	0.993	0.000
I95.2 Hypotension due to drugs	0.007	0.993	0.000
I05.2 Mitral stenosis with insufficiency	0.006	0.994	0.000
B34 Viral infection of unspecified site	0.006	0.994	0.000
I31 Other diseases of pericardium	0.006	0.994	0.000
I44.1 Atrioventricular block, second degree	0.006	0.994	0.000
I30.1 Infective pericarditis	0.006	0.994	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.994	0.006
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.006	0.994	0.000
I01.8 Other acute rheumatic heart disease	0.006	0.994	0.000
I01.2 Acute rheumatic myocarditis	0.006	0.994	0.000
I01.1 Acute rheumatic endocarditis	0.006	0.994	0.000
I01.0 Acute rheumatic pericarditis	0.006	0.994	0.000
I02.9 Rheumatic chorea without heart involvement	0.006	0.994	0.000
I02.0 Rheumatic chorea with heart involvement	0.006	0.994	0.000
I07.9 Tricuspid valve disease, unspecified	0.006	0.994	0.000
I07.8 Other tricuspid valve diseases	0.006	0.994	0.000
I07.2 Tricuspid stenosis with insufficiency	0.006	0.994	0.000
I07.0 Tricuspid stenosis	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
N80.8 Other endometriosis	0.000	0.994	0.006
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
I49.2 Junctional premature depolarisation	0.006	0.994	0.000
I50.0 Congestive heart failure	0.006	0.994	0.000
I95.8 Other hypotension	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.994	0.000
I49.9 Cardiac arrhythmia, unspecified	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.005	0.994	0.000
I95.0 Idiopathic hypotension	0.005	0.995	0.000
I35.0 Aortic (valve) stenosis	0.005	0.995	0.000
I97.1 Other functional disturbances following cardiac surgery	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
B34.4 Papovirus infection, unspecified	0.005	0.995	0.000
B34.8 Other viral infections of unspecified site	0.005	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.005	0.995	0.000
I42.2 Other hypertrophic cardiomyopathy	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
B34.1 Enterovirus infection, unspecified	0.005	0.995	0.000
X23.9 Unspecified place	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.005	0.995	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.005	0.995	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.995	0.005
B34.3 Parvovirus infection, unspecified	0.005	0.995	0.000
B34.2 Coronavirus infection, unspecified	0.005	0.995	0.000
B34.0 Adenovirus infection, unspecified	0.005	0.995	0.000
I31.8 Other specified diseases of pericardium	0.005	0.995	0.000
I31.2 Haemopericardium, not elsewhere classified	0.005	0.995	0.000
I47.1 Supraventricular tachycardia	0.005	0.995	0.000
M25.86 Other specified joint disorders (Lower leg)	0.005	0.995	0.000
I31.0 Chronic adhesive pericarditis	0.005	0.995	0.000
R17 Unspecified jaundice	0.005	0.995	0.000
M25.88 Other specified joint disorders (Other)	0.005	0.995	0.000
M25.8 Other specified joint disorders	0.005	0.995	0.000
I49.4 Other and unspecified premature depolarisation	0.004	0.996	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.004	0.996	0.000
G93.9 Disorder of brain, unspecified	0.004	0.996	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.004	0.996	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.004	0.996	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.004	0.996	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.004	0.996	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.996	0.004
I31.9 Disease of pericardium, unspecified	0.004	0.996	0.000
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.004	0.996	0.000
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
M25.82 Other specified joint disorders (Upper arm)	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
I31.3 Pericardial effusion (noninflammatory)	0.004	0.996	0.000
S71.1 Open wound of thigh	0.004	0.996	0.000
I49.8 Other specified cardiac arrhythmias	0.004	0.996	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.004	0.996	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.004	0.996	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.004	0.996	0.000
I49.5 Sick sinus syndrome	0.004	0.996	0.000
Z95.2 Presence of prosthetic heart valve	0.004	0.996	0.000
M25.83 Other specified joint disorders (Forearm)	0.004	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.004	0.996	0.000
I31.1 Chronic constrictive pericarditis	0.003	0.996	0.000
I49.3 Ventricular premature depolarisation	0.004	0.996	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.996	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.996	0.000
X23 Contact with hornets, wasps and bees	0.003	0.997	0.000
I51.8 Other ill-defined heart diseases	0.003	0.997	0.000
J95.8 Other postprocedural respiratory disorders	0.003	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
Z95.4 Presence of other heart-valve replacement	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
X23.0 Home	0.003	0.997	0.000
I51 Complications and ill-defined descriptions of heart disease	0.003	0.997	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.003	0.997	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.003	0.997	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
Z95.3 Presence of xenogenic heart valve	0.003	0.997	0.000
H33.5 Other retinal detachments	0.000	0.997	0.003
I28 Other diseases of pulmonary vessels	0.003	0.997	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.997	0.003
Z95.8 Presence of other cardiac and vascular implants and grafts	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.003	0.997	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
X23.8 Other specified place	0.003	0.997	0.000
X23.7 Farm	0.003	0.997	0.000
X23.6 Industrial and construction area	0.003	0.997	0.000
X23.5 Trade and service area	0.003	0.997	0.000
X23.4 Street and highway	0.003	0.997	0.000
X23.3 Sports and athletics area	0.003	0.997	0.000
X23.2 School, other institution and public administrative area	0.003	0.997	0.000
X23.1 Residential institution	0.003	0.997	0.000
C50.0 Nipple and areola	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
L50.9 Urticaria, unspecified	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
I12 Hypertensive renal disease	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
M89.3 Hypertrophy of bone	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.003	0.997	0.000
M89.6 Osteopathy after poliomyelitis	0.003	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.003	0.997	0.000
M89.2 Other disorders of bone development and growth	0.003	0.997	0.000
M89.1 Epiphyseal arrest	0.003	0.997	0.000
I13 Hypertensive heart and renal disease	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
F30.0 Hypomania	0.000	0.997	0.003
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.997	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.003	0.997	0.000
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.997	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.997	0.000
B25-B34 Other viral diseases	0.002	0.997	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.998	0.002
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
H10 Conjunctivitis	0.000	0.998	0.002
K52 Other non-infective gastro-enteritis and colitis	0.002	0.998	0.000
O63.0 Prolonged first stage (of labour)	0.002	0.998	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
F34.1 Dysthymia	0.000	0.998	0.002
H18.4 Corneal degeneration	0.000	0.998	0.002
I51.0 Cardiac septal defect, acquired	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations