TreeWAS – Variant ID: rs10946507

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O46.9 Antepartum haemorrhage, unspecified	0.088	0.912	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.922	0.078
S82.4 Fracture of fibula alone	0.000	0.955	0.045
S82.41 Fracture of fibula alone (open)	0.000	0.967	0.032
M67.8 Other specified disorders of synovium and tendon	0.031	0.969	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.028	0.972	0.000
S82 Fracture of lower leg, including ankle	0.000	0.978	0.022
M67 Other disorders of synovium and tendon	0.021	0.979	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.979	0.021
O46.0 Antepartum haemorrhage with coagulation defect	0.020	0.980	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.981	0.019
S82.5 Fracture of medial malleolus	0.000	0.981	0.019
M67.2 Synovial hypertrophy, not elsewhere classified	0.019	0.981	0.000
F31.9 Bipolar affective disorder, unspecified	0.019	0.981	0.000
H02.1 Ectropion of eyelid	0.019	0.981	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.019	0.981	0.000
F31 Bipolar affective disorder	0.017	0.983	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.983	0.016
S82.50 Fracture of medial malleolus (closed)	0.000	0.983	0.017
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.016	0.984	0.000
O46.8 Other antepartum haemorrhage	0.016	0.984	0.000
M67.0 Short Achilles tendon (acquired)	0.016	0.984	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.984	0.016
Z71.8 Other specified counselling	0.000	0.985	0.015
S82.2 Fracture of shaft of tibia	0.000	0.985	0.015
M67.9 Disorder of synovium and tendon, unspecified	0.015	0.985	0.000
M67.3 Transient synovitis	0.015	0.985	0.000
S82.86 Maisonneuve's fracture	0.000	0.985	0.015
S82.9 Fracture of lower leg, part unspecified	0.000	0.985	0.015
S82.3 Fracture of lower end of tibia	0.000	0.985	0.015
M67.4 Ganglion	0.014	0.985	0.000
S82.0 Fracture of patella	0.000	0.986	0.014
S82.7 Multiple fractures of lower leg	0.000	0.986	0.014
M67.1 Other contracture of tendon (sheath)	0.014	0.986	0.000
F31.8 Other bipolar affective disorders	0.013	0.986	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.987	0.013
S82.1 Fracture of upper end of tibia	0.000	0.987	0.013
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.013	0.987	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.012	0.988	0.000
I10 Essential (primary) hypertension	0.012	0.988	0.000
S82.01 Fracture of patella (open)	0.000	0.988	0.012
F31.7 Bipolar affective disorder, currently in remission	0.011	0.988	0.000
M67.43 Ganglion, wrist	0.011	0.988	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.011	0.988	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.989	0.011
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.011	0.989	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.011	0.989	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.989	0.011
S82.11 Fracture of upper end of tibia (open)	0.000	0.989	0.011
M67.49 Ganglion, multiple sites	0.011	0.989	0.000
M67.45 Ganglion, hip	0.011	0.989	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.011	0.989	0.000
H53.8 Other visual disturbances	0.010	0.990	0.000
S82.6 Fracture of lateral malleolus	0.000	0.990	0.010
S82.71 Multiple fractures of lower leg (open)	0.000	0.990	0.010
S82.21 Fracture of shaft of tibia (open)	0.000	0.990	0.010
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.990	0.010
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.990	0.010
I12.0 Hypertensive renal disease with renal failure	0.009	0.991	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.009	0.991	0.000
M67.47 Ganglion, ankle and foot	0.009	0.991	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.009	0.991	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.009	0.991	0.000
I12 Hypertensive renal disease	0.009	0.991	0.000
S82.70 Multiple fractures of lower leg (closed)	0.000	0.991	0.008
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.991	0.009
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.009	0.991	0.000
I10-I15 Hypertensive diseases	0.008	0.992	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.008	0.992	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.992	0.008
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.992	0.008
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.992	0.008
M81.40 Drug-induced osteoporosis (Multiple sites)	0.008	0.992	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.007	0.993	0.000
I12.9 Hypertensive renal disease without renal failure	0.007	0.993	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.993	0.007
S82.00 Fracture of patella (closed)	0.000	0.993	0.007
I13 Hypertensive heart and renal disease	0.007	0.993	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.006	0.994	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.006	0.994	0.000
I60 Subarachnoid haemorrhage	0.006	0.994	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.000	0.994	0.006
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.000	0.994	0.006
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.000	0.994	0.006
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.000	0.994	0.006
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.000	0.994	0.006
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.000	0.994	0.006
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.000	0.994	0.006
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.000	0.994	0.006
M75.5 Bursitis of shoulder	0.000	0.994	0.006
I60.9 Subarachnoid haemorrhage, unspecified	0.006	0.994	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.006	0.994	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.005	0.995	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.005	0.995	0.000
C34.9 Bronchus or lung, unspecified	0.005	0.995	0.000
S72.20 Subtrochanteric fracture (closed)	0.005	0.995	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.005	0.995	0.000
H93.1 Tinnitus	0.005	0.995	0.000
I15 Secondary hypertension	0.005	0.995	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.005	0.995	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.005	0.995	0.000
I60.8 Other subarachnoid haemorrhage	0.005	0.995	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.995	0.005
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.005	0.995	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.995	0.005
S82.30 Fracture of lower end of tibia (closed)	0.000	0.995	0.004
I60.5 Subarachnoid haemorrhage from vertebral artery	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
S52.10 Fracture of upper end of radius (closed)	0.004	0.996	0.000
J40 Bronchitis, not specified as acute or chronic	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
N80.1 Endometriosis of ovary	0.004	0.996	0.000
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
I11 Hypertensive heart disease	0.004	0.996	0.000
Z80 Family history of malignant neoplasm	0.000	0.996	0.004
I15.8 Other secondary hypertension	0.004	0.996	0.000
I15.2 Hypertension secondary to endocrine disorders	0.004	0.996	0.000
I15.0 Renovascular hypertension	0.004	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.004	0.996	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.004	0.996	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.996	0.004
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.004	0.996	0.000
C34.1 Upper lobe, bronchus or lung	0.004	0.996	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.996	0.004
Q61.0 Congenital single renal cyst	0.003	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
K63.1 Perforation of intestine (nontraumatic)	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.997	0.003
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.997	0.003
Q61.4 Renal dysplasia	0.003	0.997	0.000
C34 Malignant neoplasm of bronchus and lung	0.003	0.997	0.000
Z80.6 Family history of leukaemia	0.000	0.997	0.003
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
I15.9 Seconday hypertension, unspecified	0.003	0.997	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.997	0.003
Q63.0 Accessory kidney	0.003	0.997	0.000
S72.2 Subtrochanteric fracture	0.003	0.997	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.997	0.003
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.997	0.003
C34.2 Middle lobe, bronchus or lung	0.003	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.997	0.003
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
I15.1 Hypertension secondary to other renal disorders	0.003	0.997	0.000
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.997	0.003
M54.22 Cervicalgia (Cervical region)	0.000	0.997	0.003
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
C34.8 Overlapping lesion of bronchus and lung	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.997	0.003
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.997	0.003
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
K05.3 Chronic periodontitis	0.000	0.997	0.003
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
Y83.0 Surgical operation with transplant of whole organ	0.000	0.997	0.003
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.997	0.003
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
M65-M68 Disorders of synovium and tendon	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.003	0.997	0.000
J38.3 Other diseases of vocal cords	0.003	0.997	0.000
O44.1 Placenta praevia with haemorrhage	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.000	0.997	0.003
L08.8 Other specified local infections of skin and subcutaneous tissue	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
S72.21 Subtrochanteric fracture (open)	0.002	0.997	0.000
Q60.6 Potter's syndrome	0.002	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.997	0.000
Q63.2 Ectopic kidney	0.002	0.997	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.997	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.002	0.997	0.000
K05.1 Chronic gingivitis	0.000	0.997	0.003
M81.48 Drug-induced osteoporosis (Other)	0.002	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.997	0.000
Z71.6 Tobacco abuse counselling	0.000	0.997	0.002
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
M17.1 Other primary gonarthrosis	0.002	0.998	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.998	0.002
Z71.5 Drug abuse counselling and surveillance	0.000	0.998	0.002
Z71.0 Person consulting on behalf of another person	0.000	0.998	0.002
Q64.4 Malformation of urachus	0.002	0.998	0.000
Z71.2 Person consulting for explanation of investigation findings	0.000	0.998	0.002
J39.2 Other diseases of pharynx	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
K05 Gingivitis and periodontal diseases	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
Z81.8 Family history of other mental and behavioural disorders	0.002	0.998	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
K05.5 Other periodontal diseases	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
K38.9 Disease of appendix, unspecified	0.000	0.998	0.002
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
X23.0 Home	0.000	0.998	0.002
D23.0 Skin of lip	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
K05.4 Periodontosis	0.000	0.998	0.002
K38 Other diseases of appendix	0.000	0.998	0.002
C84.5 Other and unspecified T-cell lymphomas	0.002	0.998	0.000
K38.0 Hyperplasia of appendix	0.000	0.998	0.002
S52.1 Fracture of upper end of radius	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
K05.2 Acute periodontitis	0.000	0.998	0.002
Z71.9 Counselling, unspecified	0.000	0.998	0.002
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
K05.0 Acute gingivitis	0.000	0.998	0.002
T90.4 Sequelae of injury of eye and orbit	0.000	0.998	0.002
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.002	0.998	0.000
K05.6 Periodontal disease, unspecified	0.000	0.998	0.002
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
Z40 Prophylactic surgery	0.000	0.998	0.002
T63.4 Venom of other arthropods	0.000	0.998	0.002
C30.0 Nasal cavity	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
L08 Other local infections of skin and subcutaneous tissue	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.000	0.998	0.002
M43.62 Torticollis-Cervical	0.002	0.998	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
K38.3 Fistula of appendix	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.001	0.998	0.000
K05.22 Aggressive periodontitis, generalized	0.000	0.998	0.001
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
K56.2 Volvulus	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.002	0.998	0.000
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
K38.2 Diverticulum of appendix	0.000	0.998	0.001
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
R02 Gangrene, not elsewhere classified	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
S51.0 Open wound of elbow	0.000	0.998	0.002
Z40.9 Prophylactic surgery, unspecified	0.000	0.998	0.002
M25.56 Pain in joint (Lower leg)	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.998	0.002
S72.91 Fracture of femur, part unspecified (open)	0.001	0.998	0.000
C34.0 Main bronchus	0.001	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
C30 Malignant neoplasm of nasal cavity and middle ear	0.001	0.998	0.000
F38 Other mood [affective] disorders	0.001	0.998	0.000
G91 Hydrocephalus	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.001	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
G91.8 Other hydrocephalus	0.001	0.998	0.000
R06.2 Wheezing	0.002	0.998	0.000
Z40.8 Other prophylactic surgery	0.000	0.998	0.001
F38.0 Other single mood [affective] disorders	0.001	0.998	0.000
K38.1 Appendicular concretions	0.000	0.998	0.001
C84.0 Mycosis fungoides	0.001	0.998	0.000
J86.0 Pyothorax with fistula	0.000	0.998	0.001
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.001
X23 Contact with hornets, wasps and bees	0.000	0.998	0.001
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.002	0.998	0.000
E85.8 Other amyloidosis	0.001	0.998	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.001	0.998	0.000
L08.1 Erythrasma	0.001	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.998	0.001
T90.3 Sequelae of injury of cranial nerves	0.000	0.998	0.001
G91.1 Obstructive hydrocephalus	0.001	0.999	0.000
I45.5 Other specified heart block	0.000	0.999	0.001
M75.9 Shoulder lesion, unspecified	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.999	0.001
Y84.1 Kidney dialysis	0.001	0.999	0.000
L00 Staphylococcal scalded skin syndrome	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.001	0.999	0.000
F34.8 Other persistent mood [affective] disorders	0.001	0.999	0.000
S72.7 Multiple fractures of femur	0.001	0.999	0.000
C32 Malignant neoplasm of larynx	0.001	0.999	0.000
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.999	0.001
T90.8 Sequelae of other specified injuries of head	0.000	0.999	0.001
M66.5 Spontaneous rupture of unspecified tendon	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
Z98.0 Intestinal bypass and anastomosis status	0.001	0.999	0.000
E85 Amyloidosis	0.001	0.999	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.001	0.999	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.001	0.999	0.000
C30.1 Middle ear	0.001	0.999	0.000
F38.1 Other recurrent mood [affective] disorders	0.001	0.999	0.000
M66.1 Rupture of synovium	0.001	0.999	0.000
S72.8 Fractures of other parts of femur	0.001	0.999	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.999	0.000
F38.8 Other specified mood [affective] disorders	0.001	0.999	0.000
G91.0 Communicating hydrocephalus	0.001	0.999	0.000
M77.02 Medial epicondylitis (Upper arm)	0.001	0.999	0.000
X23.8 Other specified place	0.000	0.999	0.001
X23.7 Farm	0.000	0.999	0.001
X23.6 Industrial and construction area	0.000	0.999	0.001
X23.5 Trade and service area	0.000	0.999	0.001
X23.4 Street and highway	0.000	0.999	0.001
X23.3 Sports and athletics area	0.000	0.999	0.001
X23.2 School, other institution and public administrative area	0.000	0.999	0.001
X23.1 Residential institution	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.999	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.999	0.001
L08.0 Pyoderma	0.001	0.999	0.000
M82.1 Osteoporosis in endocrine disorders	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
B17.1 Acute hepatitis C	0.000	0.999	0.001
F30.9 Manic episode, unspecified	0.001	0.999	0.000
F34.1 Dysthymia	0.001	0.999	0.000
H47.2 Optic atrophy	0.001	0.999	0.000
O21.0 Mild hyperemesis gravidarum	0.001	0.999	0.000
O32.2 Maternal care for transverse and oblique lie	0.000	0.999	0.001
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.001	0.999	0.000
C80 Malignant neoplasm without specification of site	0.000	0.999	0.001
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.000	0.999	0.001
M66.3 Spontaneous rupture of flexor tendons	0.001	0.999	0.000
M66.2 Spontaneous rupture of extensor tendons	0.001	0.999	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.999	0.001
Z80.9 Family history of malignant neoplasm, unspecified	0.001	0.999	0.001
Z95.8 Presence of other cardiac and vascular implants and grafts	0.001	0.999	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.999	0.000
C32.8 Overlapping lesion of larynx	0.001	0.999	0.000
C32.3 Laryngeal cartilage	0.001	0.999	0.000
C32.2 Subglottis	0.001	0.999	0.000
E85.4 Organ-limited amyloidosis	0.001	0.999	0.000
Y40.3 Macrolides	0.001	0.999	0.000
L01 Impetigo	0.001	0.999	0.000
M66.19 Rupture of synovium (Site unspecified)	0.001	0.999	0.000
M66.18 Rupture of synovium (Other)	0.001	0.999	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.001	0.999	0.000
M66.16 Rupture of synovium (Lower leg)	0.001	0.999	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.001	0.999	0.000
M66.14 Rupture of synovium (Hand)	0.001	0.999	0.000
M66.13 Rupture of synovium (Forearm)	0.001	0.999	0.000
M66.12 Rupture of synovium (Upper arm)	0.001	0.999	0.000
M66.11 Rupture of synovium (Shoulder region)	0.001	0.999	0.000
M66.10 Rupture of synovium (Multiple sites)	0.001	0.999	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.999	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.999	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.999	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.999	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.999	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.999	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.999	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.999	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.999	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.999	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.999	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.999	0.000
I86.4 Gastric varices	0.000	0.999	0.001
T90.1 Sequelae of open wound of head	0.000	0.999	0.001
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.001	0.999	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.999	0.001
N92.4 Excessive bleeding in the premenopausal period	0.001	0.999	0.000
J39 Other diseases of upper respiratory tract	0.001	0.999	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.999	0.001
L04 Acute lymphadenitis	0.001	0.999	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.001	0.999	0.000
T90.5 Sequelae of intracranial injury	0.000	0.999	0.001
C31 Malignant neoplasm of accessory sinuses	0.001	0.999	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.001	0.999	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.001	0.999	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.001	0.999	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.001	0.999	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.001	0.999	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.001	0.999	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.001	0.999	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.001	0.999	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.001	0.999	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.999	0.001
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.999	0.001
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.999	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.999	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.999	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.999	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.999	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.999	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
E66.8 Other obesity	0.001	0.999	0.000
L05.9 Pilonidal cyst without abscess	0.001	0.999	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.000	0.999	0.001
C84.4 Peripheral T-cell lymphoma	0.001	0.999	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.999	0.001
L01.1 Impetiginisation of other dermatoses	0.001	0.999	0.000
F30 Manic episode	0.001	0.999	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
C39.9 Ill-defined sites within the respiratory system	0.001	0.999	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.001	0.999	0.000
C39.0 Upper respiratory tract, part unspecified	0.001	0.999	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.999	0.001
C84.9 Mature T/NK-cell lymphoma, unspecified	0.001	0.999	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.001	0.999	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.001	0.999	0.000
C84.3 Lymphoepithelioid lymphoma	0.001	0.999	0.000
C84.2 T-zone lymphoma	0.001	0.999	0.000
C84.1 Sezary's diease	0.001	0.999	0.000
L04.1 Acute lymphadenitis of trunk	0.001	0.999	0.000
M66.4 Spontaneous rupture of other tendons	0.001	0.999	0.000
M66.0 Rupture of popliteal cyst	0.001	0.999	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.999	0.000
S50.9 Superficial injury of forearm, unspecified	0.001	0.999	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.001	0.999	0.000
L05 Pilonidal cyst	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
S72.31 Fracture of shaft of femur (open)	0.001	0.999	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.001	0.999	0.000
J95.5 Postprocedural subglottic stenosis	0.000	0.999	0.001
J95.4 Mendelson's syndrome	0.000	0.999	0.001
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.999	0.001
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.999	0.001
L04.8 Acute lymphadenitis of other sites	0.001	0.999	0.000
L04.3 Acute lymphadenitis of lower limb	0.001	0.999	0.000
L04.2 Acute lymphadenitis of upper limb	0.001	0.999	0.000
Z56.0 Unemployment, unspecified	0.000	0.999	0.001
H47 Other disorders of optic [2nd] nerve and visual pathways	0.001	0.999	0.000
M21.27 Flexion deformity (Ankle and foot)	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
C31.9 Accessory sinus, unspecified	0.001	0.999	0.000
C31.8 Overlapping lesion of accessory sinuses	0.001	0.999	0.000
C31.3 Sphenoidal sinus	0.001	0.999	0.000
C31.2 Frontal sinus	0.001	0.999	0.000
C31.1 Ethmoidal sinus	0.001	0.999	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.999	0.001
D56.1 Beta thalassaemia	0.000	0.999	0.001
J39.9 Disease of upper respiratory tract, unspecified	0.001	0.999	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.999	0.001
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.999	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.999	0.001
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.999	0.001
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.001	0.999	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations