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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10946933
log Bayes Factor = 19.2974
Chromosome 6   position 27,471,098  (GRCh37) Explore rs10946933 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.539 0.461
E10.9 Without complications
0.000 0.541 0.459
E10.5 With peripheral circulatory complications
0.000 0.580 0.420
E10.6 With other specified complications
0.000 0.587 0.413
E10.4 With neurological complications
0.000 0.591 0.409
E10.3 With ophthalmic complications
0.000 0.612 0.388
E10.1 With ketoacidosis
0.000 0.613 0.387
E10.8 With unspecified complications
0.000 0.633 0.367
E10.7 With multiple complications
0.000 0.669 0.331
E10.0 With coma
0.000 0.670 0.330
E10.2 With renal complications
0.000 0.671 0.329
E10-E14 Diabetes mellitus
0.000 0.723 0.277
E13 Other specified diabetes mellitus
0.000 0.762 0.238
K90 Intestinal malabsorption
0.000 0.773 0.227
E83 Disorders of mineral metabolism
0.000 0.789 0.211
E13.9 Without complications
0.000 0.790 0.210
E12 Malnutrition-related diabetes mellitus
0.000 0.801 0.199
E13.8 With unspecified complications
0.000 0.829 0.170
E13.7 With multiple complications
0.000 0.829 0.170
E13.6 With other specified complications
0.000 0.829 0.170
E13.5 With peripheral circulatory complications
0.000 0.829 0.170
E13.4 With neurological complications
0.000 0.829 0.170
E13.2 With renal complications
0.000 0.829 0.170
E13.1 With ketoacidosis
0.000 0.829 0.170
E13.0 With coma
0.000 0.829 0.170
E13.3 With ophthalmic complications
0.000 0.832 0.168
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.833 0.167
E70-E90 Metabolic disorders
0.000 0.834 0.166
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.834 0.166
E14 Unspecified diabetes mellitus
0.000 0.835 0.165
K90.3 Pancreatic steatorrhoea
0.000 0.837 0.163
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.837 0.163
K90.1 Tropical sprue
0.000 0.837 0.163
E88 Other metabolic disorders
0.000 0.841 0.159
K90.8 Other intestinal malabsorption
0.000 0.845 0.155
E14.3 With ophthalmic complications
0.000 0.847 0.153
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.848 0.152
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.848 0.152
E83.8 Other disorders of mineral metabolism
0.000 0.848 0.152
E83.2 Disorders of zinc metabolism
0.000 0.848 0.152
E83.0 Disorders of copper metabolism
0.000 0.848 0.152
E11 Non-insulin-dependent diabetes mellitus
0.000 0.852 0.148
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.852 0.148
E12.9 Without complications
0.000 0.857 0.143
E12.8 With unspecified complications
0.000 0.857 0.143
E12.7 With multiple complications
0.000 0.857 0.143
E12.6 With other specified complications
0.000 0.857 0.143
E12.5 With peripheral circulatory complications
0.000 0.857 0.143
E12.4 With neurological complications
0.000 0.857 0.143
E12.3 With ophthalmic complications
0.000 0.857 0.143
E12.2 With renal complications
0.000 0.857 0.143
E12.1 With ketoacidosis
0.000 0.857 0.143
E12.0 With coma
0.000 0.857 0.143
E16 Other disorders of pancreatic internal secretion
0.000 0.859 0.141
E16.2 Hypoglycaemia, unspecified
0.000 0.865 0.135
E40-E46 Malnutrition
0.000 0.868 0.132
E85 Amyloidosis
0.000 0.873 0.127
E88.8 Other specified metabolic disorders
0.000 0.874 0.126
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.874 0.126
E88.2 Lipomatosis, not elsewhere classified
0.000 0.876 0.124
E14.5 With peripheral circulatory complications
0.000 0.876 0.124
E11.2 With renal complications
0.000 0.877 0.123
E88.3 Tumour lysis syndrome
0.000 0.880 0.120
E84 Cystic fibrosis
0.000 0.881 0.119
E77 Disorders of glycoprotein metabolism
0.000 0.881 0.119
E76 Disorders of glycosaminoglycan metabolism
0.000 0.881 0.119
E72 Other disorders of amino-acid metabolism
0.000 0.881 0.119
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.881 0.119
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.881 0.119
E11.0 With coma
0.000 0.881 0.119
E14.7 With multiple complications
0.000 0.881 0.119
E14.2 Withrenal complications
0.000 0.881 0.119
E14.0 With coma
0.000 0.881 0.119
E11.4 With neurological complications
0.000 0.885 0.115
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.885 0.115
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.886 0.114
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.886 0.114
E14.4 With neurological complications
0.000 0.887 0.113
E11.1 With ketoacidosis
0.000 0.887 0.113
E70 Disorders of aromatic amino-acid metabolism
0.000 0.889 0.111
E14.6 With other specified complications
0.000 0.890 0.110
E15 Nondiabetic hypoglycaemic coma
0.000 0.891 0.109
E14.1 With ketoacidosis
0.000 0.893 0.107
E46 Unspecified protein-energy malnutrition
0.000 0.893 0.107
E11.7 With multiple complications
0.000 0.894 0.106
E88.9 Metabolic disorder, unspecified
0.000 0.894 0.106
E79 Disorders of purine and pyrimidine metabolism
0.000 0.894 0.106
E83.3 Disorders of phosphorus metabolism
0.000 0.895 0.105
E11.8 With unspecified complications
0.000 0.895 0.105
E11.5 With peripheral circulatory complications
0.000 0.897 0.103
E85.9 Amyloidosis, unspecified
0.000 0.898 0.102
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.898 0.101
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.898 0.101
E16.4 Abnormal secretion of gastrin
0.000 0.898 0.101
E16.3 Increased secretion of glucagon
0.000 0.898 0.101
E11.6 With other specified complications
0.000 0.902 0.098
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.905 0.095
E45 Retarded development following protein-energy malnutrition
0.000 0.905 0.095
E43 Unspecified severe protein-energy malnutrition
0.000 0.905 0.095
E42 Marasmic kwashiorkor
0.000 0.905 0.095
E41 Nutritional marasmus
0.000 0.905 0.095
E40 Kwashiorkor
0.000 0.905 0.095
E85.4 Organ-limited amyloidosis
0.000 0.908 0.092
E73 Lactose intolerance
0.000 0.908 0.091
E85.8 Other amyloidosis
0.000 0.909 0.091
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.909 0.091
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.909 0.091
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.909 0.091
E65-E68 Obesity and other hyperalimentation
0.000 0.909 0.091
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.910 0.090
E74 Other disorders of carbohydrate metabolism
0.000 0.911 0.088
E85.3 Secondary systemic amyloidosis
0.000 0.913 0.087
E71.3 Disorders of fatty-acid metabolism
0.000 0.914 0.086
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.914 0.086
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.914 0.086
E71.0 Maple-syrup-urine disease
0.000 0.914 0.086
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.914 0.086
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.914 0.086
E72.5 Disorders of glycine metabolism
0.000 0.914 0.086
E72.4 Disorders of ornithine metabolism
0.000 0.914 0.086
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.914 0.086
E72.2 Disorders of urea cycle metabolism
0.000 0.914 0.086
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.914 0.086
E72.0 Disorders of amino-acid transport
0.000 0.914 0.086
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.914 0.086
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.914 0.086
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.914 0.086
E76.2 Other mucopolysaccharidoses
0.000 0.914 0.086
E76.1 Mucopolysaccharidosis, type II
0.000 0.914 0.086
E76.0 Mucopolysaccharidosis, type I
0.000 0.914 0.086
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.914 0.086
E77.8 Other disorders of glycoprotein metabolism
0.000 0.914 0.086
E77.1 Defects in glycoprotein degradation
0.000 0.914 0.086
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.914 0.086
E84.9 Cystic fibrosis, unspecified
0.000 0.914 0.086
E84.8 Cystic fibrosis with other manifestations
0.000 0.914 0.086
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.914 0.086
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.914 0.086
E14.8 With unspecified complications
0.000 0.915 0.085
E80.4 Gilbert's syndrome
0.000 0.915 0.085
E75.6 Lipid storage disorder, unspecified
0.000 0.917 0.082
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.917 0.082
E75.3 Sphingolipidosis, unspecified
0.000 0.917 0.082
E75.2 Other sphingolipidosis
0.000 0.917 0.082
E75.1 Other gangliosidosis
0.000 0.917 0.082
E75.0 GM2 gangliosidosis
0.000 0.917 0.082
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.918 0.082
E80.5 Crigler-Najjar syndrome
0.000 0.918 0.082
E80.3 Defects of catalase and peroxydase
0.000 0.918 0.082
E80.1 Porphyria cutanea tarda
0.000 0.918 0.082
E80.0 Hereditary erythropoietic porphyria
0.000 0.918 0.082
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.920 0.080
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.920 0.080
E70.2 Disorders of tyrosine metabolism
0.000 0.920 0.080
E70.1 Other hyperphenylalaninaemias
0.000 0.920 0.080
E70.0 Classical phenylketonuria
0.000 0.920 0.080
E80.6 Other disorders of bilirubin metabolism
0.000 0.921 0.079
E75.5 Other lipid storage disorders
0.000 0.922 0.078
E16.1 Other hypoglycaemia
0.000 0.922 0.077
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.924 0.076
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.924 0.076
E79.1 Lesch-Nyhan syndrome
0.000 0.924 0.076
E80.2 Other porphyria
0.000 0.924 0.076
E11.3 With ophthalmic complications
0.000 0.926 0.074
K90.9 Intestinal malabsorption, unspecified
0.000 0.928 0.072
E65 Localised adiposity
0.000 0.928 0.072
E70.3 Albinism
0.000 0.928 0.072
E83.4 Disorders of magnesium metabolism
0.000 0.930 0.070
E44.1 Mild protein-energy malnutrition
0.000 0.932 0.068
E44.0 Moderate protein-energy malnutrition
0.000 0.932 0.068
E89.4 Postprocedural ovarian failure
0.000 0.932 0.068
E89.2 Postprocedural hypoparathyroidism
0.000 0.933 0.067
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.933 0.067
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.933 0.067
E73.8 Other lactose intolerance
0.000 0.934 0.066
E73.1 Secondary lactase deficiency
0.000 0.934 0.066
E73.0 Congenital lactase deficiency
0.000 0.934 0.066
E67 Other hyperalimentation
0.000 0.934 0.065
E68 Sequelae of hyperalimentation
0.000 0.934 0.065
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.935 0.065
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.935 0.065
E89.5 Postprocedural testicular hypofunction
0.000 0.935 0.065
E89.1 Postprocedural hypoinsulinaemia
0.000 0.935 0.065
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.936 0.063
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.936 0.063
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.936 0.063
E74.2 Disorders of galactose metabolism
0.000 0.936 0.063
E74.1 Disorders of fructose metabolism
0.000 0.936 0.063
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.937 0.063
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.938 0.062
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.939 0.061
E87.5 Hyperkalaemia
0.000 0.941 0.059
E50-E64 Other nutritional deficiencies
0.000 0.941 0.059
E87.0 Hyperosmolality and hypernatraemia
0.000 0.941 0.059
E74.0 Glycogen storage disease
0.000 0.943 0.057
E00-E07 Disorders of thyroid gland
0.000 0.944 0.056
E89.0 Postprocedural hypothyroidism
0.000 0.945 0.055
E87.3 Alkalosis
0.000 0.946 0.054
E87.7 Fluid overload
0.000 0.950 0.050
E78.2 Mixed hyperlipidaemia
0.000 0.951 0.049
E87.4 Mixed disorder of acid-base balance
0.000 0.952 0.048
E67.8 Other specified hyperalimentation
0.000 0.953 0.047
E67.3 Hypervitaminosis D
0.000 0.953 0.047
E67.2 Megavitamin-B6 syndrome
0.000 0.953 0.047
E67.1 Hypercarotenaemia
0.000 0.953 0.047
E67.0 Hypervitaminosis A
0.000 0.953 0.047
E14.9 Without complications
0.000 0.953 0.047
E78.4 Other hyperlipidaemia
0.000 0.954 0.046
E78.3 Hyperchylomicronaemia
0.000 0.955 0.045
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.956 0.044
E78.1 Pure hyperglyceridaemia
0.000 0.956 0.044
E78.6 Lipoprotein deficiency
0.000 0.957 0.043
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.957 0.042
E63 Other nutritional deficiencies
0.000 0.957 0.042
E50 Vitamin A deficiency
0.000 0.957 0.042
E60 Dietary zinc deficiency
0.000 0.957 0.042
E59 Dietary selenium deficiency
0.000 0.957 0.042
E54 Ascorbic acid deficiency
0.000 0.957 0.042
E52 Niacin deficiency [pellagra]
0.000 0.957 0.042
E58 Dietary calcium deficiency
0.000 0.958 0.042
E56 Other vitamin deficiencies
0.000 0.959 0.041
E51 Thiamine deficiency
0.000 0.959 0.040
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.960 0.040
E00 Congenital iodine-deficiency syndrome
0.000 0.960 0.040
E07 Other disorders of thyroid
0.000 0.960 0.040
E53 Deficiency of other B group vitamins
0.000 0.960 0.040
E06 Thyroiditis
0.000 0.961 0.039
E04 Other non-toxic goitre
0.000 0.961 0.039
E73.9 Lactose intolerance, unspecified
0.001 0.962 0.037
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.963 0.037
E89.3 Postprocedural hypopituitarism
0.000 0.963 0.036
E55 Vitamin D deficiency
0.000 0.964 0.036
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.965 0.035
E83.5 Disorders of calcium metabolism
0.000 0.966 0.034
E04.9 Non-toxic goitre, unspecified
0.000 0.966 0.034
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.969 0.031
E87.2 Acidosis
0.000 0.969 0.031
E50.9 Vitamin A deficiency, unspecified
0.000 0.969 0.031
E50.8 Other manifestations of vitamin A deficiency
0.000 0.969 0.031
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.969 0.031
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.969 0.031
E50.5 Vitamin A deficiency with night blindness
0.000 0.969 0.031
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.969 0.031
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.969 0.031
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.969 0.031
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.969 0.031
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.969 0.031
E63.9 Nutritional deficiency, unspecified
0.000 0.969 0.031
E63.8 Other specified nutritional deficiencies
0.000 0.969 0.031
E63.1 Imbalance of constituents of food intake
0.000 0.969 0.031
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.969 0.031
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.969 0.031
E64.8 Sequelae of other nutritional deficiencies
0.000 0.969 0.031
E64.3 Sequelae of rickets
0.000 0.969 0.031
E64.2 Sequelae of vitamin C deficiency
0.000 0.969 0.031
E64.1 Sequelae of vitamin A deficiency
0.000 0.969 0.031
E64.0 Sequelae of protein-energy malnutrition
0.000 0.969 0.031
E53.9 Vitamin B deficiency, unspecified
0.000 0.969 0.031
E04.0 Non-toxic diffuse goitre
0.000 0.970 0.030
E07.9 Disorder of thyroid, unspecified
0.000 0.970 0.030
E56.9 Vitamin deficiency, unspecified
0.000 0.970 0.029
E56.8 Deficiency of other vitamins
0.000 0.970 0.029
E56.0 Deficiency of vitamin E
0.000 0.970 0.029
E51.9 Thiamine deficiency, unspecified
0.000 0.971 0.029
E51.8 Other manifestations of thiamine deficiency
0.000 0.971 0.029
E51.1 Beriberi
0.000 0.971 0.029
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.971 0.029
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.971 0.029
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.971 0.029
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.971 0.029
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.971 0.029
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.971 0.029
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.971 0.029
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.971 0.029
E07.1 Dyshormogenetic goitre
0.000 0.971 0.029
E07.0 Hypersecretion of calcitonin
0.000 0.971 0.029
E53.1 Pyridoxine deficiency
0.000 0.971 0.029
E53.0 Riboflavin deficiency
0.000 0.971 0.029
E06.3 Autoimmune thyroiditis
0.000 0.972 0.028
E06.5 Other chronic thyroiditis
0.000 0.972 0.028
E06.4 Drug-induced thyroiditis
0.000 0.972 0.028
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.972 0.028
E06.1 Subacute thyroiditis
0.000 0.972 0.028
E06.0 Acute thyroiditis
0.000 0.972 0.028
E04.8 Other specified non-toxic goitre
0.000 0.972 0.028
E56.1 Deficiency of vitamin K
0.000 0.972 0.028
E07.8 Other specified disorders of thyroid
0.000 0.973 0.027
E51.2 Wernicke's encephalopathy
0.000 0.973 0.027
E06.9 Thyroiditis, unspecified
0.000 0.973 0.027
E20-E35 Disorders of other endocrine glands
0.000 0.974 0.026
E55.0 Rickets, active
0.000 0.974 0.026
E86 Volume depletion
0.000 0.974 0.026
R31 Unspecified haematuria
0.026 0.974 0.000
E05.8 Other thyrotoxicosis
0.000 0.975 0.025
E03 Other hypothyroidism
0.000 0.975 0.025
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.975 0.024
E53.8 Deficiency of other specified B group vitamins
0.000 0.977 0.023
E05.5 Thyroid crisis or storm
0.000 0.977 0.023
E05.4 Thyrotoxicosis factitia
0.000 0.977 0.023
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.977 0.023
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.977 0.023
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.977 0.023
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.978 0.022
E61 Deficiency of other nutrient elements
0.001 0.978 0.021
G31.8 Other specified degenerative diseases of nervous system
0.000 0.979 0.021
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.979 0.021
E20 Hypoparathyroidism
0.000 0.979 0.021
E78.8 Other disorders of lipoprotein metabolism
0.000 0.980 0.020
E04.1 Non-toxic single thyroid nodule
0.000 0.980 0.020
E27.1 Primary adrenocortical insufficiency
0.000 0.980 0.020
E26 Hyperaldosteronism
0.000 0.980 0.020
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.980 0.020
E55.9 Vitamin D deficiency, unspecified
0.000 0.980 0.019
E29 Testicular dysfunction
0.000 0.981 0.019
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.981 0.019
E32 Diseases of thymus
0.000 0.981 0.019
E31 Polyglandular dysfunction
0.000 0.981 0.019
E30 Disorders of puberty, not elsewhere classified
0.000 0.981 0.019
E25 Adrenogenital disorders
0.000 0.981 0.019
E03.8 Other specified hypothyroidism
0.000 0.981 0.019
E27 Other disorders of adrenal gland
0.000 0.981 0.019
G31.0 Circumscribed brain atrophy
0.000 0.981 0.019
E04.2 Non-toxic multinodular goitre
0.000 0.981 0.019
G30 Alzheimer's disease
0.000 0.982 0.018
E03.5 Myxoedema coma
0.000 0.982 0.018
E03.4 Atrophy of thyroid (acquired)
0.000 0.982 0.018
E03.3 Postinfectious hypothyroidism
0.000 0.982 0.018
E03.1 Congenital hypothyroidism without goitre
0.000 0.982 0.018
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.982 0.018
E24 Cushing's syndrome
0.000 0.982 0.018
G30-G32 Other degenerative diseases of the nervous system
0.000 0.982 0.018
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.983 0.017
E66 Obesity
0.000 0.983 0.017
E20.9 Hypoparathyroidism, unspecified
0.000 0.983 0.017
E34 Other endocrine disorders
0.000 0.983 0.017
G30.9 Alzheimer's disease, unspecified
0.000 0.983 0.017
E23 Hypofunction and other disorders of pituitary gland
0.000 0.983 0.016
G30.0 Alzheimer's disease with early onset
0.000 0.984 0.016
E61.9 Deficiency of nutrient element, unspecified
0.001 0.984 0.015
E61.8 Deficiency of other specified nutrient elements
0.001 0.984 0.015
E61.7 Deficiency of multiple nutrient elements
0.001 0.984 0.015
E61.6 Vanadium deficiency
0.001 0.984 0.015
E61.5 Molybdenum deficiency
0.001 0.984 0.015
E61.4 Chromium deficiency
0.001 0.984 0.015
E61.3 Manganese deficiency
0.001 0.984 0.015
E61.0 Copper deficiency
0.001 0.984 0.015
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.984 0.015
E26.0 Primary hyperaldosteronism
0.000 0.984 0.015
E24.2 Drug-induced Cushing's syndrome
0.000 0.985 0.015
E20.8 Other hypoparathyroidism
0.000 0.985 0.015
E20.1 Pseudohypoparathyroidism
0.000 0.985 0.015
E20.0 Idiopathic hypoparathyroidism
0.000 0.985 0.015
K90-K93 Other diseases of the digestive system
0.000 0.985 0.015
E23.2 Diabetes insipidus
0.000 0.985 0.015
E26.9 Hyperaldosteronism, unspecified
0.000 0.985 0.014
E26.8 Other hyperaldosteronism
0.000 0.985 0.014
E26.1 Secondary hyperaldosteronism
0.000 0.985 0.014
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.985 0.014
G30.8 Other Alzheimer's disease
0.000 0.986 0.014
M25.57 Pain in joint (Ankle and foot)
0.000 0.986 0.014
E29.9 Testicular dysfunction, unspecified
0.000 0.986 0.014
E29.8 Other testicular dysfunction
0.000 0.986 0.014
E29.0 Testicular hyperfunction
0.000 0.986 0.014
E29.1 Testicular hypofunction
0.000 0.986 0.014
E25.9 Adrenogenital disorder, unspecified
0.000 0.986 0.014
E25.8 Other adrenogenital disorders
0.000 0.986 0.014
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.986 0.014
E30.9 Disorder of puberty, unspecified
0.000 0.986 0.014
E30.8 Other disorders of puberty
0.000 0.986 0.014
E30.1 Precocious puberty
0.000 0.986 0.014
E30.0 Delayed puberty
0.000 0.986 0.014
E31.9 Polyglandular dysfunction, unspecified
0.000 0.986 0.014
E31.8 Other polyglandular dysfunction
0.000 0.986 0.014
E31.1 Polyglandular hyperfunction
0.000 0.986 0.014
E31.0 Autoimmune polyglandular failure
0.000 0.986 0.014
E32.9 Disease of thymus, unspecified
0.000 0.986 0.014
E32.8 Other diseases of thymus
0.000 0.986 0.014
E32.1 Abscess of thymus
0.000 0.986 0.014
E32.0 Persistent hyperplasia of thymus
0.000 0.986 0.014
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.986 0.014
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.986 0.014
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.986 0.014
E27.5 Adrenomedullary hyperfunction
0.000 0.986 0.014
E27.0 Other adrenocortical overactivity
0.000 0.986 0.014
E28 Ovarian dysfunction
0.000 0.986 0.014
G30.1 Alzheimer's disease with late onset
0.000 0.987 0.013
E24.8 Other Cushing's syndrome
0.000 0.987 0.013
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.987 0.013
E24.3 Ectopic ACTH syndrome
0.000 0.987 0.013
E24.1 Nelson's syndrome
0.000 0.987 0.013
G31.2 Degeneration of nervous system due to alcohol
0.000 0.987 0.013
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.987 0.013
M25.5 Pain in joint
0.000 0.987 0.013
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.987 0.013
E66.1 Drug-induced obesity
0.000 0.987 0.012
E61.2 Magnesium deficiency
0.001 0.987 0.012
E34.5 Androgen resistance syndrome
0.000 0.988 0.012
E34.4 Constitutional tall stature
0.000 0.988 0.012
E34.3 Short stature, not elsewhere classified
0.000 0.988 0.012
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.988 0.012
E34.1 Other hypersecretion of intestinal hormones
0.000 0.988 0.012
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.988 0.012
E23.1 Drug-induced hypopituitarism
0.000 0.988 0.012
E24.0 Pituitary-dependent Cushing's disease
0.000 0.988 0.012
E34.0 Carcinoid syndrome
0.000 0.988 0.012
E87.6 Hypokalaemia
0.000 0.988 0.012
E23.7 Disorder of pituitary gland, unspecified
0.000 0.988 0.011
E66.0 Obesity due to excess calories
0.000 0.988 0.011
E27.2 Addisonian crisis
0.000 0.989 0.011
E34.8 Other specified endocrine disorders
0.000 0.989 0.011
E34.9 Endocrine disorder, unspecified
0.000 0.989 0.011
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.989 0.011
M25.58 Pain in joint (Other)
0.000 0.989 0.011
E23.6 Other disorders of pituitary gland
0.000 0.989 0.010
M25.51 Pain in joint (Shoulder region)
0.000 0.989 0.011
M25.52 Pain in joint (Upper arm)
0.000 0.990 0.010
E28.9 Ovarian dysfunction, unspecified
0.000 0.990 0.010
E28.8 Other ovarian dysfunction
0.000 0.990 0.010
E28.1 Androgen excess
0.000 0.990 0.010
E28.0 Oestrogen excess
0.000 0.990 0.010
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.990 0.010
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.990 0.010
G44.2 Tension-type headache
0.010 0.990 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.990 0.009
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.991 0.009
E24.9 Cushing's syndrome, unspecified
0.000 0.991 0.009
E27.8 Other specified disorders of adrenal gland
0.000 0.991 0.009
M25.54 Pain in joint (Hand)
0.000 0.991 0.009
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.991 0.009
K22.8 Other specified diseases of oesophagus
0.009 0.991 0.000
M25.53 Pain in joint (Forearm)
0.000 0.991 0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.992 0.008
K93.1 Megacolon in Chagas' disease
0.000 0.992 0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.992 0.008
E21.4 Other specified disorders of parathyroid gland
0.000 0.992 0.007
E21.2 Other hyperparathyroidism
0.000 0.992 0.007
E27.9 Disorder of adrenal gland, unspecified
0.001 0.993 0.007
E22 Hyperfunction of pituitary gland
0.000 0.993 0.007
E21.3 Hyperparathyroidism, unspecified
0.000 0.993 0.007
E11.9 Without complications
0.000 0.993 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.993 0.006
E28.3 Primary ovarian failure
0.001 0.994 0.006
Z34.9 Supervision of normal pregnancy, unspecified
0.006 0.994 0.000
M25.59 Pain in joint (Site unspecified)
0.000 0.994 0.006
E23.0 Hypopituitarism
0.000 0.994 0.006
E21.0 Primary hyperparathyroidism
0.000 0.994 0.006
M67.8 Other specified disorders of synovium and tendon
0.000 0.994 0.006
E61.1 Iron deficiency
0.001 0.994 0.004
E22.8 Other hyperfunction of pituitary gland
0.000 0.995 0.005
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.995 0.005
G82.5 Tetraplegia, unspecified
0.000 0.995 0.005
G44 Other headache syndromes
0.005 0.995 0.000
E22.1 Hyperprolactinaemia
0.000 0.995 0.005
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.995 0.004
G82.4 Spastic tetraplegia
0.000 0.995 0.005
G54.9 Nerve root and plexus disorder, unspecified
0.005 0.995 0.000
N60.1 Diffuse cystic mastopathy
0.000 0.995 0.005
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.005 0.995 0.000
G82 Paraplegia and tetraplegia
0.000 0.995 0.005
G44.8 Other specified headache syndromes
0.004 0.995 0.000
K56.4 Other impaction of intestine
0.004 0.996 0.000
G82.1 Spastic paraplegia
0.000 0.996 0.004
K02.9 Dental caries, unspecified
0.000 0.996 0.004
K22.0 Achalasia of cardia
0.004 0.996 0.000
K02.8 Other dental caries
0.000 0.996 0.004
G71.1 Myotonic disorders
0.000 0.996 0.004
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.996 0.004
G44.1 Vascular headache, not elsewhere classified
0.004 0.996 0.000
M79.10 Myalgia (Multiple sites)
0.004 0.996 0.000
K22.5 Diverticulum of oesophagus, acquired
0.004 0.996 0.000
N04.9 Unspecified
0.000 0.996 0.004
G44.0 Cluster headache syndrome
0.004 0.996 0.000
M25.50 Pain in joint (Multiple sites)
0.000 0.996 0.004
G44.4 Drug-induced headache, not elsewhere classified
0.004 0.996 0.000
G82.3 Flaccid tetraplegia
0.000 0.996 0.004
G82.0 Flaccid paraplegia
0.000 0.996 0.004
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.996 0.003
G44.3 Chronic posttraumatic headache
0.003 0.996 0.000
K02 Dental caries
0.000 0.996 0.004
E05.9 Thyrotoxicosis, unspecified
0.000 0.996 0.004
K22 Other diseases of oesophagus
0.003 0.997 0.000
G71 Primary disorders of muscles
0.000 0.997 0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.003 0.997 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.997 0.003
E22.0 Acromegaly and pituitary gigantism
0.001 0.997 0.003
E66.9 Obesity, unspecified
0.000 0.997 0.003
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.997 0.003
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.997 0.003
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.997 0.003
M41.9 Scoliosis, unspecified
0.003 0.997 0.000
K56.2 Volvulus
0.003 0.997 0.000
K02.1 Caries of dentin
0.000 0.997 0.003
G82.2 Paraplegia, unspecified
0.000 0.997 0.003
M67 Other disorders of synovium and tendon
0.000 0.997 0.003
C71.2 Temporal lobe
0.003 0.997 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.003 0.997 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.003 0.997 0.000
M67.4 Ganglion
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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