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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10946990
log Bayes Factor = 41.7563
Chromosome 6   position 29,396,646  (GRCh37) Explore rs10946990 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.022 0.978
E10.1 With ketoacidosis
0.000 0.029 0.971
E13 Other specified diabetes mellitus
0.000 0.045 0.955
E10.2 With renal complications
0.000 0.046 0.954
E13.9 Without complications
0.000 0.062 0.938
E10.4 With neurological complications
0.000 0.089 0.911
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.181 0.819
E10.6 With other specified complications
0.000 0.181 0.819
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.189 0.811
E16 Other disorders of pancreatic internal secretion
0.000 0.193 0.807
E16.2 Hypoglycaemia, unspecified
0.000 0.200 0.800
E10.0 With coma
0.000 0.215 0.785
E14 Unspecified diabetes mellitus
0.000 0.228 0.772
E10.5 With peripheral circulatory complications
0.000 0.232 0.768
E10.7 With multiple complications
0.000 0.283 0.717
E00-E07 Disorders of thyroid gland
0.000 0.289 0.711
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.296 0.704
E12 Malnutrition-related diabetes mellitus
0.000 0.299 0.701
E05.9 Thyrotoxicosis, unspecified
0.000 0.304 0.696
E16.1 Other hypoglycaemia
0.000 0.305 0.695
E13.8 With unspecified complications
0.000 0.315 0.684
E13.7 With multiple complications
0.000 0.315 0.684
E13.6 With other specified complications
0.000 0.315 0.684
E13.5 With peripheral circulatory complications
0.000 0.315 0.684
E13.4 With neurological complications
0.000 0.315 0.684
E13.3 With ophthalmic complications
0.000 0.315 0.684
E13.2 With renal complications
0.000 0.315 0.684
E13.1 With ketoacidosis
0.000 0.315 0.684
E13.0 With coma
0.000 0.315 0.684
E10.8 With unspecified complications
0.000 0.337 0.663
E20-E35 Disorders of other endocrine glands
0.000 0.350 0.650
E05.8 Other thyrotoxicosis
0.000 0.388 0.612
E14.9 Without complications
0.000 0.392 0.608
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.394 0.606
E23 Hypofunction and other disorders of pituitary gland
0.000 0.407 0.593
E14.2 Withrenal complications
0.000 0.413 0.587
E15 Nondiabetic hypoglycaemic coma
0.000 0.418 0.582
E14.4 With neurological complications
0.000 0.419 0.581
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.421 0.578
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.421 0.578
E16.4 Abnormal secretion of gastrin
0.000 0.421 0.578
E16.3 Increased secretion of glucagon
0.000 0.421 0.578
E50-E64 Other nutritional deficiencies
0.000 0.425 0.575
E14.8 With unspecified complications
0.000 0.433 0.566
E24 Cushing's syndrome
0.000 0.442 0.558
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.443 0.557
E14.1 With ketoacidosis
0.000 0.444 0.556
E14.7 With multiple complications
0.000 0.446 0.554
E14.6 With other specified complications
0.000 0.446 0.554
E14.5 With peripheral circulatory complications
0.000 0.446 0.554
E14.0 With coma
0.000 0.446 0.554
E23.0 Hypopituitarism
0.000 0.464 0.536
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.469 0.531
E11 Non-insulin-dependent diabetes mellitus
0.000 0.469 0.531
E20 Hypoparathyroidism
0.000 0.479 0.521
E40-E46 Malnutrition
0.000 0.481 0.519
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.490 0.510
E00 Congenital iodine-deficiency syndrome
0.000 0.490 0.510
E23.2 Diabetes insipidus
0.000 0.492 0.508
E22 Hyperfunction of pituitary gland
0.000 0.492 0.508
E05.5 Thyroid crisis or storm
0.000 0.495 0.505
E05.4 Thyrotoxicosis factitia
0.000 0.495 0.505
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.495 0.505
E12.9 Without complications
0.000 0.497 0.503
E12.8 With unspecified complications
0.000 0.497 0.503
E12.7 With multiple complications
0.000 0.497 0.503
E12.6 With other specified complications
0.000 0.497 0.503
E12.5 With peripheral circulatory complications
0.000 0.497 0.503
E12.4 With neurological complications
0.000 0.497 0.503
E12.3 With ophthalmic complications
0.000 0.497 0.503
E12.2 With renal complications
0.000 0.497 0.503
E12.1 With ketoacidosis
0.000 0.497 0.503
E12.0 With coma
0.000 0.497 0.503
E29 Testicular dysfunction
0.000 0.507 0.493
E14.3 With ophthalmic complications
0.000 0.513 0.487
E24.9 Cushing's syndrome, unspecified
0.000 0.525 0.475
E55 Vitamin D deficiency
0.000 0.525 0.475
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.534 0.466
E32 Diseases of thymus
0.000 0.534 0.466
E30 Disorders of puberty, not elsewhere classified
0.000 0.534 0.466
E25 Adrenogenital disorders
0.000 0.534 0.466
E11.2 With renal complications
0.000 0.543 0.457
E11.6 With other specified complications
0.000 0.544 0.456
E07 Other disorders of thyroid
0.000 0.547 0.453
E28 Ovarian dysfunction
0.000 0.561 0.439
E23.7 Disorder of pituitary gland, unspecified
0.000 0.566 0.434
E24.2 Drug-induced Cushing's syndrome
0.000 0.567 0.433
E20.9 Hypoparathyroidism, unspecified
0.000 0.571 0.429
E11.0 With coma
0.000 0.572 0.428
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.575 0.425
E23.1 Drug-induced hypopituitarism
0.000 0.575 0.425
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.576 0.424
E31 Polyglandular dysfunction
0.000 0.580 0.420
E53 Deficiency of other B group vitamins
0.000 0.581 0.419
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.587 0.412
E63 Other nutritional deficiencies
0.000 0.587 0.412
E56 Other vitamin deficiencies
0.000 0.587 0.412
E51 Thiamine deficiency
0.000 0.587 0.412
E50 Vitamin A deficiency
0.000 0.587 0.412
E60 Dietary zinc deficiency
0.000 0.587 0.412
E59 Dietary selenium deficiency
0.000 0.587 0.412
E54 Ascorbic acid deficiency
0.000 0.587 0.412
E52 Niacin deficiency [pellagra]
0.000 0.587 0.412
E22.0 Acromegaly and pituitary gigantism
0.000 0.590 0.410
E06 Thyroiditis
0.000 0.595 0.405
E55.9 Vitamin D deficiency, unspecified
0.000 0.597 0.403
E24.8 Other Cushing's syndrome
0.000 0.600 0.400
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.600 0.400
E24.3 Ectopic ACTH syndrome
0.000 0.600 0.400
E24.1 Nelson's syndrome
0.000 0.600 0.400
E24.0 Pituitary-dependent Cushing's disease
0.000 0.600 0.400
E27 Other disorders of adrenal gland
0.000 0.604 0.396
E11.1 With ketoacidosis
0.000 0.606 0.394
E11.8 With unspecified complications
0.000 0.612 0.388
E34 Other endocrine disorders
0.000 0.612 0.388
E29.1 Testicular hypofunction
0.000 0.619 0.381
E11.7 With multiple complications
0.000 0.619 0.380
E26 Hyperaldosteronism
0.000 0.624 0.376
E20.8 Other hypoparathyroidism
0.000 0.626 0.374
E20.1 Pseudohypoparathyroidism
0.000 0.626 0.374
E20.0 Idiopathic hypoparathyroidism
0.000 0.626 0.374
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.628 0.372
E45 Retarded development following protein-energy malnutrition
0.000 0.628 0.372
E43 Unspecified severe protein-energy malnutrition
0.000 0.628 0.372
E42 Marasmic kwashiorkor
0.000 0.628 0.372
E41 Nutritional marasmus
0.000 0.628 0.372
E40 Kwashiorkor
0.000 0.628 0.372
E53.9 Vitamin B deficiency, unspecified
0.000 0.628 0.372
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.634 0.366
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.634 0.366
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.634 0.366
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.634 0.366
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.634 0.366
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.634 0.366
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.634 0.366
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.634 0.366
K90 Intestinal malabsorption
0.000 0.634 0.366
E22.1 Hyperprolactinaemia
0.000 0.636 0.364
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.636 0.364
E22.8 Other hyperfunction of pituitary gland
0.000 0.636 0.364
E58 Dietary calcium deficiency
0.000 0.641 0.359
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.642 0.358
E61 Deficiency of other nutrient elements
0.000 0.645 0.355
E29.9 Testicular dysfunction, unspecified
0.000 0.646 0.354
E29.8 Other testicular dysfunction
0.000 0.646 0.354
E29.0 Testicular hyperfunction
0.000 0.646 0.354
E11.5 With peripheral circulatory complications
0.000 0.658 0.342
E07.8 Other specified disorders of thyroid
0.000 0.658 0.342
E55.0 Rickets, active
0.000 0.659 0.340
E23.6 Other disorders of pituitary gland
0.000 0.662 0.338
E28.3 Primary ovarian failure
0.000 0.664 0.336
E25.9 Adrenogenital disorder, unspecified
0.000 0.666 0.334
E25.8 Other adrenogenital disorders
0.000 0.666 0.334
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.666 0.334
E30.9 Disorder of puberty, unspecified
0.000 0.666 0.334
E30.8 Other disorders of puberty
0.000 0.666 0.334
E30.1 Precocious puberty
0.000 0.666 0.334
E30.0 Delayed puberty
0.000 0.666 0.334
E32.9 Disease of thymus, unspecified
0.000 0.666 0.334
E32.8 Other diseases of thymus
0.000 0.666 0.334
E32.1 Abscess of thymus
0.000 0.666 0.334
E32.0 Persistent hyperplasia of thymus
0.000 0.666 0.334
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.666 0.334
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.666 0.334
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.666 0.334
E27.1 Primary adrenocortical insufficiency
0.000 0.666 0.334
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.672 0.328
E06.9 Thyroiditis, unspecified
0.000 0.672 0.328
E83 Disorders of mineral metabolism
0.326 0.674 0.000
E07.1 Dyshormogenetic goitre
0.000 0.675 0.325
E07.0 Hypersecretion of calcitonin
0.000 0.675 0.325
E03 Other hypothyroidism
0.000 0.684 0.316
E28.9 Ovarian dysfunction, unspecified
0.000 0.685 0.315
E28.8 Other ovarian dysfunction
0.000 0.685 0.315
E28.1 Androgen excess
0.000 0.685 0.315
E28.0 Oestrogen excess
0.000 0.685 0.315
E46 Unspecified protein-energy malnutrition
0.000 0.695 0.304
E31.9 Polyglandular dysfunction, unspecified
0.000 0.699 0.301
E31.8 Other polyglandular dysfunction
0.000 0.699 0.301
E31.1 Polyglandular hyperfunction
0.000 0.699 0.301
E53.1 Pyridoxine deficiency
0.000 0.699 0.300
E53.0 Riboflavin deficiency
0.000 0.699 0.300
E50.9 Vitamin A deficiency, unspecified
0.000 0.704 0.296
E50.8 Other manifestations of vitamin A deficiency
0.000 0.704 0.296
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.704 0.296
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.704 0.296
E50.5 Vitamin A deficiency with night blindness
0.000 0.704 0.296
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.704 0.296
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.704 0.296
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.704 0.296
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.704 0.296
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.704 0.296
E51.9 Thiamine deficiency, unspecified
0.000 0.704 0.296
E51.8 Other manifestations of thiamine deficiency
0.000 0.704 0.296
E51.2 Wernicke's encephalopathy
0.000 0.704 0.296
E51.1 Beriberi
0.000 0.704 0.296
E56.9 Vitamin deficiency, unspecified
0.000 0.704 0.296
E56.8 Deficiency of other vitamins
0.000 0.704 0.296
E56.1 Deficiency of vitamin K
0.000 0.704 0.296
E56.0 Deficiency of vitamin E
0.000 0.704 0.296
E63.9 Nutritional deficiency, unspecified
0.000 0.704 0.296
E63.8 Other specified nutritional deficiencies
0.000 0.704 0.296
E63.1 Imbalance of constituents of food intake
0.000 0.704 0.296
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.704 0.296
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.704 0.296
E64.8 Sequelae of other nutritional deficiencies
0.000 0.704 0.296
E64.3 Sequelae of rickets
0.000 0.704 0.296
E64.2 Sequelae of vitamin C deficiency
0.000 0.704 0.296
E64.1 Sequelae of vitamin A deficiency
0.000 0.704 0.296
E64.0 Sequelae of protein-energy malnutrition
0.000 0.704 0.296
E06.4 Drug-induced thyroiditis
0.000 0.709 0.291
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.709 0.291
E06.1 Subacute thyroiditis
0.000 0.709 0.291
E06.0 Acute thyroiditis
0.000 0.709 0.291
E34.8 Other specified endocrine disorders
0.000 0.712 0.288
E11.4 With neurological complications
0.000 0.715 0.285
E27.5 Adrenomedullary hyperfunction
0.000 0.716 0.284
E27.0 Other adrenocortical overactivity
0.000 0.716 0.284
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.718 0.282
E27.8 Other specified disorders of adrenal gland
0.000 0.721 0.279
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.721 0.279
E34.5 Androgen resistance syndrome
0.000 0.722 0.278
E34.4 Constitutional tall stature
0.000 0.722 0.278
E34.3 Short stature, not elsewhere classified
0.000 0.722 0.278
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.722 0.278
E34.1 Other hypersecretion of intestinal hormones
0.000 0.722 0.278
E26.9 Hyperaldosteronism, unspecified
0.000 0.730 0.269
E26.8 Other hyperaldosteronism
0.000 0.730 0.269
E26.1 Secondary hyperaldosteronism
0.000 0.730 0.269
E83.3 Disorders of phosphorus metabolism
0.267 0.733 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.733 0.267
E44.0 Moderate protein-energy malnutrition
0.000 0.733 0.267
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.733 0.267
K90.3 Pancreatic steatorrhoea
0.000 0.738 0.262
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.738 0.262
K90.1 Tropical sprue
0.000 0.738 0.262
E65-E68 Obesity and other hyperalimentation
0.000 0.738 0.262
E34.9 Endocrine disorder, unspecified
0.000 0.740 0.260
E28.2 Polycystic ovarian syndrome
0.000 0.742 0.257
E31.0 Autoimmune polyglandular failure
0.000 0.745 0.255
E61.9 Deficiency of nutrient element, unspecified
0.000 0.745 0.254
E61.8 Deficiency of other specified nutrient elements
0.000 0.745 0.254
E61.7 Deficiency of multiple nutrient elements
0.000 0.745 0.254
E61.6 Vanadium deficiency
0.000 0.745 0.254
E61.5 Molybdenum deficiency
0.000 0.745 0.254
E61.4 Chromium deficiency
0.000 0.745 0.254
E61.3 Manganese deficiency
0.000 0.745 0.254
E61.0 Copper deficiency
0.000 0.745 0.254
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.749 0.251
E27.9 Disorder of adrenal gland, unspecified
0.000 0.753 0.247
E03.8 Other specified hypothyroidism
0.000 0.754 0.246
K90.8 Other intestinal malabsorption
0.000 0.757 0.243
E07.9 Disorder of thyroid, unspecified
0.000 0.761 0.238
E83.9 Disorder of mineral metabolism, unspecified
0.234 0.766 0.000
E83.8 Other disorders of mineral metabolism
0.234 0.766 0.000
E83.2 Disorders of zinc metabolism
0.234 0.766 0.000
E83.0 Disorders of copper metabolism
0.234 0.766 0.000
E61.2 Magnesium deficiency
0.000 0.770 0.229
E83.4 Disorders of magnesium metabolism
0.228 0.772 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.772 0.228
E61.1 Iron deficiency
0.000 0.772 0.228
E06.5 Other chronic thyroiditis
0.000 0.773 0.227
E03.5 Myxoedema coma
0.000 0.773 0.227
E03.4 Atrophy of thyroid (acquired)
0.000 0.773 0.227
E03.3 Postinfectious hypothyroidism
0.000 0.773 0.227
E03.1 Congenital hypothyroidism without goitre
0.000 0.773 0.227
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.773 0.227
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.787 0.213
E34.0 Carcinoid syndrome
0.000 0.790 0.210
E06.3 Autoimmune thyroiditis
0.000 0.804 0.196
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.807 0.193
E27.2 Addisonian crisis
0.000 0.807 0.193
E67 Other hyperalimentation
0.000 0.812 0.188
E68 Sequelae of hyperalimentation
0.000 0.812 0.188
E21.4 Other specified disorders of parathyroid gland
0.000 0.820 0.180
E21.2 Other hyperparathyroidism
0.000 0.820 0.180
E26.0 Primary hyperaldosteronism
0.001 0.820 0.179
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.173 0.827 0.000
E04 Other non-toxic goitre
0.001 0.835 0.165
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.839 0.161
E21.3 Hyperparathyroidism, unspecified
0.000 0.843 0.156
E04.9 Non-toxic goitre, unspecified
0.000 0.854 0.146
E11.3 With ophthalmic complications
0.000 0.863 0.137
E53.8 Deficiency of other specified B group vitamins
0.000 0.863 0.137
E65 Localised adiposity
0.000 0.863 0.136
E67.8 Other specified hyperalimentation
0.000 0.865 0.135
E67.3 Hypervitaminosis D
0.000 0.865 0.135
E67.2 Megavitamin-B6 syndrome
0.000 0.865 0.135
E67.1 Hypercarotenaemia
0.000 0.865 0.135
E67.0 Hypervitaminosis A
0.000 0.865 0.135
E11.9 Without complications
0.000 0.881 0.119
E04.8 Other specified non-toxic goitre
0.001 0.881 0.118
E83.5 Disorders of calcium metabolism
0.118 0.882 0.000
I83 Varicose veins of lower extremities
0.085 0.915 0.000
K51 Ulcerative colitis
0.077 0.923 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.073 0.927 0.000
K51.4 Pseudopolyposis of colon
0.073 0.927 0.000
K51.9 Ulcerative colitis, unspecified
0.073 0.927 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.929 0.070
I83.1 Varicose veins of lower extremities with inflammation
0.069 0.931 0.000
K51.2 Ulcerative (chronic) proctitis
0.069 0.931 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.065 0.935 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.065 0.935 0.000
K51.5 Mucosal proctocolitis
0.060 0.940 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.055 0.945 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.052 0.948 0.000
K51.8 Other ulcerative colitis
0.047 0.952 0.000
E21.0 Primary hyperparathyroidism
0.000 0.953 0.046
K50-K52 Noninfective enteritis and colitis
0.028 0.972 0.000
E66 Obesity
0.000 0.973 0.027
K50 Crohn's disease [regional enteritis]
0.025 0.975 0.000
K50.9 Crohn's disease, unspecified
0.023 0.977 0.000
V18.0 Driver injured in nontraffic accident
0.022 0.978 0.000
K90-K93 Other diseases of the digestive system
0.001 0.978 0.021
K50.0 Crohn's disease of small intestine
0.021 0.979 0.000
H54.0 Blindness, both eyes
0.000 0.980 0.020
E66.1 Drug-induced obesity
0.000 0.980 0.020
E04.1 Non-toxic single thyroid nodule
0.001 0.980 0.019
K50.1 Crohn's disease of large intestine
0.017 0.982 0.000
H54 Blindness and low vision
0.000 0.983 0.017
H54.9 Unspecified visual impairment (binocular)
0.000 0.983 0.017
A08.4 Viral intestinal infection, unspecified
0.000 0.984 0.016
E66.0 Obesity due to excess calories
0.000 0.984 0.016
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.984 0.016
K50.8 Other Crohn's disease
0.015 0.985 0.000
E04.2 Non-toxic multinodular goitre
0.001 0.985 0.014
H54.6 Unqualified visual loss, one eye
0.000 0.985 0.015
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.014
H54.7 Unspecified visual loss
0.000 0.986 0.014
H54.5 Low vision, one eye
0.000 0.986 0.014
F45.8 Other somatoform disorders
0.000 0.987 0.013
H54.3 Unqualified visual loss, both eyes
0.000 0.987 0.013
V18 Pedal cyclist injured in noncollision transport accident
0.012 0.988 0.000
H54.2 Low vision, both eyes
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.988 0.011
K93.1 Megacolon in Chagas' disease
0.001 0.988 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.988 0.011
C43.5 Malignant melanoma of trunk
0.000 0.989 0.011
H54.1 Blindness, one eye, low vision, other eye
0.000 0.989 0.011
E70-E90 Metabolic disorders
0.003 0.989 0.007
H54.4 Blindness, one eye
0.000 0.989 0.011
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.989 0.011
J38.4 Oedema of larynx
0.010 0.990 0.000
J38.7 Other diseases of larynx
0.010 0.990 0.000
V18.5 Passenger injured in traffic accident
0.009 0.991 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.009 0.991 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.009 0.991 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.009 0.991 0.000
V18.4 Driver injured in traffic accident
0.009 0.991 0.000
V18.1 Passenger injured in nontraffic accident
0.009 0.991 0.000
J38.3 Other diseases of vocal cords
0.009 0.991 0.000
E73 Lactose intolerance
0.002 0.992 0.007
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.992 0.008
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.008 0.992 0.000
V18.3 Person injured while boarding or alighting
0.008 0.992 0.000
E79 Disorders of purine and pyrimidine metabolism
0.002 0.992 0.006
E74 Other disorders of carbohydrate metabolism
0.002 0.992 0.006
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.992 0.006
E77 Disorders of glycoprotein metabolism
0.003 0.992 0.006
E76 Disorders of glycosaminoglycan metabolism
0.003 0.992 0.006
E72 Other disorders of amino-acid metabolism
0.003 0.992 0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.992 0.006
E70 Disorders of aromatic amino-acid metabolism
0.003 0.992 0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.992 0.006
E84 Cystic fibrosis
0.003 0.992 0.005
E66.8 Other obesity
0.000 0.992 0.008
J38.2 Nodules of vocal cords
0.008 0.992 0.000
F45 Somatoform disorders
0.000 0.992 0.008
E85 Amyloidosis
0.002 0.993 0.005
J38.5 Laryngeal spasm
0.007 0.993 0.000
M79.0 Rheumatism, unspecified
0.000 0.993 0.007
E73.9 Lactose intolerance, unspecified
0.001 0.993 0.006
C50.8 Overlapping lesion of breast
0.000 0.993 0.007
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.993 0.007
M79.08 Rheumatism, unspecified (Other)
0.000 0.993 0.007
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.006 0.993 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.006 0.993 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.007 0.993 0.000
C50.3 Lower-inner quadrant of breast
0.000 0.993 0.007
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.994 0.005
E73.8 Other lactose intolerance
0.001 0.994 0.005
E73.1 Secondary lactase deficiency
0.001 0.994 0.005
E73.0 Congenital lactase deficiency
0.001 0.994 0.005
F45.9 Somatoform disorder, unspecified
0.000 0.994 0.006
K04.5 Chronic apical periodontitis
0.006 0.994 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.994 0.006
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.994 0.005
V10-V19 Pedal cyclist injured in transport accident
0.006 0.994 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.994 0.004
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.994 0.004
E79.1 Lesch-Nyhan syndrome
0.002 0.994 0.004
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.994 0.006
J38.1 Polyp of vocal cord and larynx
0.006 0.994 0.000
F45.0 Somatisation disorder
0.000 0.994 0.006
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.994 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.994 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.994 0.005
E74.2 Disorders of galactose metabolism
0.002 0.994 0.005
E74.1 Disorders of fructose metabolism
0.002 0.994 0.005
E74.0 Glycogen storage disease
0.002 0.994 0.005
E75.5 Other lipid storage disorders
0.002 0.994 0.005
E75.6 Lipid storage disorder, unspecified
0.002 0.994 0.004
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.994 0.004
E75.3 Sphingolipidosis, unspecified
0.002 0.994 0.004
E75.2 Other sphingolipidosis
0.002 0.994 0.004
E75.1 Other gangliosidosis
0.002 0.994 0.004
E75.0 GM2 gangliosidosis
0.002 0.994 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.994 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.994 0.004
E70.3 Albinism
0.002 0.994 0.004
E70.2 Disorders of tyrosine metabolism
0.002 0.994 0.004
E70.1 Other hyperphenylalaninaemias
0.002 0.994 0.004
E70.0 Classical phenylketonuria
0.002 0.994 0.004
E71.3 Disorders of fatty-acid metabolism
0.002 0.994 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.994 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.994 0.004
E71.0 Maple-syrup-urine disease
0.002 0.994 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.994 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.994 0.004
E72.5 Disorders of glycine metabolism
0.002 0.994 0.004
E72.4 Disorders of ornithine metabolism
0.002 0.994 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.994 0.004
E72.2 Disorders of urea cycle metabolism
0.002 0.994 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.994 0.004
E72.0 Disorders of amino-acid transport
0.002 0.994 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.994 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.994 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.994 0.004
E76.2 Other mucopolysaccharidoses
0.002 0.994 0.004
E76.1 Mucopolysaccharidosis, type II
0.002 0.994 0.004
E76.0 Mucopolysaccharidosis, type I
0.002 0.994 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.994 0.004
E77.8 Other disorders of glycoprotein metabolism
0.002 0.994 0.004
E77.1 Defects in glycoprotein degradation
0.002 0.994 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.994 0.004
J38.6 Stenosis of larynx
0.006 0.994 0.000
F45.2 Hypochondriacal disorder
0.000 0.994 0.006
E88 Other metabolic disorders
0.002 0.994 0.004
E84.8 Cystic fibrosis with other manifestations
0.002 0.994 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.994 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.994 0.004
S42.10 Fracture of scapula (closed)
0.000 0.994 0.006
F45.1 Undifferentiated somatoform disorder
0.000 0.994 0.006
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.002 0.994 0.004
F45.3 Somatoform autonomic dysfunction
0.000 0.994 0.005
A08 Viral and other specified intestinal infections
0.000 0.994 0.006
E85.8 Other amyloidosis
0.002 0.994 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.994 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.994 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.994 0.004
F45.4 Persistent somatoform pain disorder
0.000 0.994 0.005
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.994 0.005
E85.4 Organ-limited amyloidosis
0.001 0.995 0.004
E85.3 Secondary systemic amyloidosis
0.001 0.995 0.004
D47.4 Osteomyelofibrosis
0.000 0.995 0.005
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.995 0.005
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.995 0.005
M79.04 Rheumatism, unspecified (Hand)
0.000 0.995 0.005
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.995 0.005
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.995 0.005
F41.1 Generalised anxiety disorder
0.000 0.995 0.005
V19 Pedal cyclist injured in other and unspecified transport accidents
0.005 0.995 0.000
C50 Malignant neoplasm of breast
0.000 0.995 0.005
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.995 0.003
J35.2 Hypertrophy of adenoids
0.005 0.995 0.000
N48.4 Impotence of organic origin
0.005 0.995 0.000
H53-H54 Visual disturbances and blindness
0.000 0.995 0.005
V10 Pedal cyclist injured in collision with pedestrian or animal
0.005 0.995 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.005 0.995 0.000
C50.1 Central portion of breast
0.000 0.995 0.005
E85.9 Amyloidosis, unspecified
0.001 0.995 0.004
D47.2 Monoclonal gammopathy
0.000 0.995 0.005
J35 Chronic diseases of tonsils and adenoids
0.005 0.995 0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident
0.005 0.995 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.005 0.995 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.005 0.995 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.005 0.995 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.005 0.995 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.005 0.995 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.995 0.005
R01.1 Cardiac murmur, unspecified
0.000 0.995 0.005
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.995 0.005
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.995 0.005
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.995 0.003
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.995 0.005
E88.9 Metabolic disorder, unspecified
0.002 0.995 0.003
A08.3 Other viral enteritis
0.000 0.996 0.004
M79.06 Rheumatism, unspecified (Lower leg)
0.000 0.996 0.004
E88.2 Lipomatosis, not elsewhere classified
0.001 0.996 0.003
E88.3 Tumour lysis syndrome
0.002 0.996 0.003
A08.5 Other specified intestinal infections
0.000 0.996 0.004
A08.2 Adenoviral enteritis
0.000 0.996 0.004
A08.0 Rotaviral enteritis
0.000 0.996 0.004
N18.5 Chronic kidney disease, stage 5
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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