TreeWAS – Variant ID: rs10947210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.9 Rheumatoid arthritis, unspecified	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.998	0.002	0.000
E11.9 Without complications	0.998	0.002	0.000
E11 Non-insulin-dependent diabetes mellitus	0.997	0.003	0.000
E10-E14 Diabetes mellitus	0.996	0.004	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.007	0.993
E10 Insulin-dependent diabetes mellitus	0.991	0.009	0.000
M06 Other rheumatoid arthritis	0.991	0.009	0.000
L40.9 Psoriasis, unspecified	0.990	0.010	0.000
C44 Other malignant neoplasms of skin	0.000	0.014	0.986
M05-M14 Inflammatory polyarthropathies	0.985	0.015	0.000
E10.9 Without complications	0.982	0.018	0.000
C44.4 Skin of scalp and neck	0.000	0.021	0.979
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.977	0.023	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.962	0.038	0.000
K90.0 Coeliac disease	0.000	0.066	0.934
M05 Seropositive rheumatoid arthritis	0.931	0.069	0.000
E14 Unspecified diabetes mellitus	0.916	0.084	0.000
E11.4 With neurological complications	0.915	0.085	0.000
C44.7 Skin of lower limb, including hip	0.000	0.089	0.911
M20-M25 Other joint disorders	0.906	0.094	0.000
M80-M85 Disorders of bone density and structure	0.906	0.094	0.000
M70-M79 Other soft tissue disorders	0.893	0.107	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.892	0.108	0.000
E14.9 Without complications	0.879	0.121	0.000
E11.5 With peripheral circulatory complications	0.879	0.121	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.878	0.122	0.000
L40 Psoriasis	0.874	0.126	0.000
M65-M68 Disorders of synovium and tendon	0.866	0.134	0.000
M35 Other systemic involvement of connective tissue	0.862	0.137	0.000
E10.5 With peripheral circulatory complications	0.858	0.142	0.000
M06.3 Rheumatoid nodule	0.855	0.145	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.853	0.147	0.000
M35.3 Polymyalgia rheumatica	0.852	0.148	0.000
E13 Other specified diabetes mellitus	0.847	0.153	0.000
E10.1 With ketoacidosis	0.845	0.155	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.157	0.843
M79.7 Fibromyalgia	0.838	0.162	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.832	0.168	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.832	0.168	0.000
M65 Synovitis and tenosynovitis	0.829	0.171	0.000
M12 Other specific arthropathies	0.828	0.171	0.000
M86-M90 Other osteopathies	0.824	0.176	0.000
M81 Osteoporosis without pathological fracture	0.823	0.177	0.000
M31 Other necrotising vasculopathies	0.823	0.177	0.000
M79.79 Fibromyalgia (Site unspecified)	0.816	0.184	0.000
M79.6 Pain in limb	0.813	0.187	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.809	0.191	0.000
M20 Acquired deformities of fingers and toes	0.800	0.200	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.201	0.799
M07 Psoriatic and enteropathic arthropathies	0.797	0.203	0.000
M84 Disorders of continuity of bone	0.795	0.205	0.000
M79.64 Pain in limb (Hand)	0.792	0.208	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.786	0.214	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.785	0.215	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.784	0.216	0.000
M30 Polyarteritis nodosa and related conditions	0.778	0.222	0.000
L40-L45 Papulosquamous disorders	0.776	0.224	0.000
M91-M94 Chondropathies	0.770	0.230	0.000
C44.5 Skin of trunk	0.000	0.235	0.765
E11.8 With unspecified complications	0.759	0.241	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.758	0.242	0.000
E10.3 With ophthalmic complications	0.756	0.244	0.000
Chapter XX External causes of morbidity and mortality	0.751	0.249	0.000
M31.6 Other giant cell arteritis	0.751	0.249	0.000
# Top node	0.744	0.256	0.000
E11.0 With coma	0.743	0.257	0.000
C44.0 Skin of lip	0.000	0.257	0.743
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.742	0.258	0.000
M79.2 Neuralgia and neuritis, unspecified	0.742	0.258	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.741	0.259	0.000
E13.9 Without complications	0.740	0.260	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.738	0.262	0.000
M20.5 Other deformities of toe(s) (acquired)	0.737	0.263	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.729	0.271	0.000
M76 Enthesopathies of lower limb, excluding foot	0.728	0.272	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.722	0.278	0.000
M81.4 Drug-induced osteoporosis	0.722	0.278	0.000
M89 Other disorders of bone	0.722	0.278	0.000
E10.8 With unspecified complications	0.721	0.279	0.000
M20.4 Other hammer toe(s) (acquired)	0.721	0.279	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.720	0.280	0.000
M24 Other specific joint derangements	0.719	0.281	0.000
E10.6 With other specified complications	0.718	0.282	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.716	0.284	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.715	0.285	0.000
E11.7 With multiple complications	0.715	0.285	0.000
E12 Malnutrition-related diabetes mellitus	0.714	0.286	0.000
M06.4 Inflammatory polyarthropathy	0.712	0.288	0.000
M06.34 Rheumatoid nodule (Hand)	0.712	0.288	0.000
E10.7 With multiple complications	0.711	0.289	0.000
M06.8 Other specified rheumatoid arthritis	0.710	0.289	0.000
M06.2 Rheumatoid bursitis	0.710	0.289	0.000
M06.1 Adult-onset Still's disease	0.710	0.289	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.710	0.290	0.000
L40.0 Psoriasis vulgaris	0.709	0.291	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.708	0.292	0.000
E10.0 With coma	0.708	0.292	0.000
C44.8 Overlapping lesion of skin	0.000	0.293	0.707
M09 Juvenile arthritis in diseases classified elsewhere	0.706	0.294	0.000
M08 Juvenile arthritis	0.706	0.294	0.000
M10 Gout	0.702	0.298	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.699	0.301	0.000
M14 Arthropathies in other diseases classified elsewhere	0.695	0.305	0.000
M79.1 Myalgia	0.692	0.307	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.692	0.308	0.000
M35.1 Other overlap syndromes	0.690	0.310	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.689	0.311	0.000
M79.0 Rheumatism, unspecified	0.689	0.311	0.000
M60-M63 Disorders of muscles	0.688	0.312	0.000
M81.9 Osteoporosis, unspecified	0.688	0.312	0.000
M79.61 Pain in limb (Shoulder region)	0.685	0.315	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.678	0.322	0.000
M71 Other bursopathies	0.676	0.324	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.675	0.325	0.000
W20-W49 Exposure to inanimate mechanical forces	0.674	0.326	0.000
M12.3 Palindromic rheumatism	0.674	0.326	0.000
M65.8 Other synovitis and tenosynovitis	0.674	0.326	0.000
M00-M03 Infectious arthropathies	0.670	0.330	0.000
M05.8 Other seropositive rheumatoid arthritis	0.667	0.333	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.667	0.333	0.000
M05.2 Rheumatoid vasculitis	0.667	0.333	0.000
M05.1 Rheumatoid lung disease	0.667	0.333	0.000
M05.0 Felty's syndrome	0.667	0.333	0.000
Y84.6 Urinary catheterisation	0.664	0.336	0.000
M07.3 Other psoriatic arthropathies	0.663	0.337	0.000
M86 Osteomyelitis	0.660	0.340	0.000
M12.2 Villonodular synovitis (pigmented)	0.659	0.341	0.000
E50-E64 Other nutritional deficiencies	0.658	0.342	0.000
E40-E46 Malnutrition	0.657	0.343	0.000
E14.8 With unspecified complications	0.657	0.343	0.000
E14.7 With multiple complications	0.657	0.343	0.000
E14.6 With other specified complications	0.657	0.343	0.000
E14.5 With peripheral circulatory complications	0.657	0.343	0.000
E14.4 With neurological complications	0.657	0.343	0.000
E14.2 Withrenal complications	0.657	0.343	0.000
E14.1 With ketoacidosis	0.657	0.343	0.000
E14.0 With coma	0.657	0.343	0.000
M84.0 Malunion of fracture	0.656	0.344	0.000
M80 Osteoporosis with pathological fracture	0.655	0.345	0.000
M66 Spontaneous rupture of synovium and tendon	0.653	0.347	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.649	0.350	0.000
M33 Dermatopolymyositis	0.649	0.350	0.000
M83 Adult osteomalacia	0.649	0.351	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.646	0.354	0.000
M89.0 Algoneurodystrophy	0.645	0.355	0.000
Chapter VIII Diseases of the ear and mastoid process	0.643	0.357	0.000
Y83.4 Other reconstructive surgery	0.642	0.358	0.000
M92 Other juvenile osteochondrosis	0.642	0.358	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.641	0.359	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.641	0.359	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.640	0.359	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.640	0.360	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.640	0.360	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.640	0.360	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.640	0.360	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.640	0.360	0.000
M82 Osteoporosis in diseases classified elsewhere	0.639	0.361	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.638	0.362	0.000
M32 Systemic lupus erythematosus	0.636	0.364	0.000
M84.3 Stress fracture, not elsewhere classified	0.632	0.368	0.000
M81.98 Osteoporosis, unspecified (Other)	0.631	0.369	0.000
M79.9 Soft tissue disorder, unspecified	0.630	0.370	0.000
M79.3 Panniculitis, unspecified	0.630	0.370	0.000
L40.8 Other psoriasis	0.627	0.373	0.000
L40.4 Guttate psoriasis	0.627	0.373	0.000
L40.3 Pustulosis palmaris et plantaris	0.627	0.373	0.000
L40.2 Acrodermatitis continua	0.627	0.373	0.000
L40.1 Generalised pustular psoriasis	0.627	0.373	0.000
M65.1 Other infective (teno)synovitis	0.626	0.374	0.000
E10.4 With neurological complications	0.624	0.376	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.621	0.379	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.621	0.379	0.000
M85 Other disorders of bone density and structure	0.619	0.381	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.618	0.381	0.000
M35.8 Other specified systemic involvement of connective tissue	0.618	0.381	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.618	0.381	0.000
M35.5 Multifocal fibrosclerosis	0.618	0.381	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.618	0.381	0.000
M35.2 Behcet's disease	0.618	0.381	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.617	0.383	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.617	0.383	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.616	0.384	0.000
M11 Other crystal arthropathies	0.616	0.384	0.000
E65-E68 Obesity and other hyperalimentation	0.615	0.385	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.613	0.387	0.000
M06.38 Rheumatoid nodule (Other)	0.613	0.387	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.613	0.387	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.613	0.387	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.613	0.387	0.000
M06.33 Rheumatoid nodule (Forearm)	0.613	0.387	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.613	0.387	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.613	0.387	0.000
M25 Other joint disorders, not elsewhere classified	0.612	0.388	0.000
W50-W64 Exposure to animate mechanical forces	0.612	0.388	0.000
Y83.0 Surgical operation with transplant of whole organ	0.611	0.389	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.611	0.389	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.611	0.389	0.000
M76.6 Achilles tendinitis	0.609	0.391	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.608	0.392	0.000
E13.8 With unspecified complications	0.607	0.393	0.000
E13.7 With multiple complications	0.607	0.393	0.000
E13.6 With other specified complications	0.607	0.393	0.000
E13.5 With peripheral circulatory complications	0.607	0.393	0.000
E13.4 With neurological complications	0.607	0.393	0.000
E13.3 With ophthalmic complications	0.607	0.393	0.000
E13.2 With renal complications	0.607	0.393	0.000
E13.1 With ketoacidosis	0.607	0.393	0.000
E13.0 With coma	0.607	0.393	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.607	0.393	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.603	0.397	0.000
M79.78 Fibromyalgia (Other)	0.601	0.399	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.601	0.399	0.000
M79.76 Fibromyalgia (Lower leg)	0.601	0.399	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.601	0.399	0.000
M79.74 Fibromyalgia (Hand)	0.601	0.399	0.000
M79.73 Fibromyalgia (Forearm)	0.601	0.399	0.000
M79.72 Fibromyalgia (Upper arm)	0.601	0.399	0.000
M79.71 Fibromyalgia (Shoulder region)	0.601	0.399	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.600	0.400	0.000
E10.2 With renal complications	0.600	0.400	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.597	0.403	0.000
E61 Deficiency of other nutrient elements	0.597	0.403	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.596	0.404	0.000
M65.2 Calcific tendinitis	0.595	0.405	0.000
M65.0 Abscess of tendon sheath	0.595	0.405	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.594	0.406	0.000
M12.5 Traumatic arthropathy	0.594	0.406	0.000
M12.4 Intermittent hydrarthrosis	0.594	0.406	0.000
M12.1 Kaschin-Beck disease	0.594	0.406	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.594	0.406	0.000
E11.6 With other specified complications	0.593	0.407	0.000
W25 Contact with sharp glass	0.593	0.407	0.000
M79.67 Pain in limb (Ankle and foot)	0.591	0.409	0.000
M20.0 Deformity of finger(s)	0.591	0.409	0.000
Y83.5 Amputation of limb(s)	0.591	0.409	0.000
M81.8 Other osteoporosis	0.590	0.410	0.000
M81.6 Localised osteoporosis [Lequesne]	0.590	0.410	0.000
M81.5 Idiopathic osteoporosis	0.590	0.410	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.590	0.410	0.000
M81.2 Osteoporosis of disuse	0.590	0.410	0.000
M81.1 Postoophorectomy osteoporosis	0.590	0.410	0.000
M81.0 Postmenopausal osteoporosis	0.590	0.410	0.000
M31.9 Necrotising vasculopathy, unspecified	0.590	0.410	0.000
M31.8 Other specified necrotising vasculopathies	0.590	0.410	0.000
M31.7 Microscopic polyangiitis	0.590	0.410	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.590	0.410	0.000
M31.2 Lethal midline granuloma	0.590	0.410	0.000
M31.1 Thrombotic microangiopathy	0.590	0.410	0.000
M31.0 Hypersensitivity angiitis	0.590	0.410	0.000
E11.2 With renal complications	0.590	0.410	0.000
X60-X84 Intentional self-harm	0.590	0.410	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.589	0.411	0.000
V01-V09 Pedestrian injured in transport accident	0.588	0.412	0.000
M88 Paget's disease of bone [osteitis deformans]	0.587	0.412	0.000
M65.3 Trigger finger	0.587	0.413	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.587	0.413	0.000
W00-W19 Falls	0.586	0.414	0.000
M30.0 Polyarteritis nodosa	0.583	0.417	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.583	0.417	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.583	0.417	0.000
M79.68 Pain in limb (Other)	0.583	0.417	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.582	0.418	0.000
M24.0 Loose body in joint	0.580	0.420	0.000
M20.1 Hallux valgus (acquired)	0.580	0.420	0.000
X50-X57 Overexertion, travel and privation	0.577	0.423	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.577	0.423	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.577	0.423	0.000
S90-S99 Injuries to the ankle and foot	0.576	0.424	0.000
M79.69 Pain in limb (Site unspecified)	0.573	0.427	0.000
M07.6 Other enteropathic arthropathies	0.572	0.428	0.000
M07.5 Arthropathy in ulcerative colitis	0.572	0.428	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.572	0.428	0.000
M07.2 Psoriatic spondylitis	0.572	0.428	0.000
M07.1 Arthritis mutilans	0.572	0.428	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.572	0.428	0.000
M84.9 Disorder of continuity of bone, unspecified	0.570	0.430	0.000
M84.8 Other disorders of continuity of bone	0.570	0.430	0.000
M84.2 Delayed union of fracture	0.570	0.430	0.000
M87 Osteonecrosis	0.570	0.430	0.000
M31.3 Wegener's granulomatosis	0.569	0.430	0.000
M40-M43 Deforming dorsopathies	0.567	0.433	0.000
E46 Unspecified protein-energy malnutrition	0.566	0.434	0.000
M84.4 Pathological fracture, not elsewhere classified	0.565	0.434	0.000
M79.5 Residual foreign body in soft tissue	0.565	0.434	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.565	0.435	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.565	0.435	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.563	0.437	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.563	0.437	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.563	0.437	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.563	0.437	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.563	0.437	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.563	0.437	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.563	0.437	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.563	0.437	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.563	0.437	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.563	0.437	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.563	0.437	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.562	0.438	0.000
M89.5 Osteolysis	0.562	0.438	0.000
H60-H62 Diseases of external ear	0.560	0.440	0.000
L40.5 Arthropathic psoriasis	0.559	0.441	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.558	0.442	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.558	0.442	0.000
M30.2 Juvenile polyarteritis	0.558	0.442	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.558	0.442	0.000
M84.04 Malunion of fracture (Hand)	0.557	0.443	0.000
L44 Other papulosquamous disorders	0.556	0.444	0.000
L41 Parapsoriasis	0.556	0.444	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.556	0.444	0.000
L42 Pityriasis rosea	0.556	0.444	0.000
M24.7 Protrusio acetabuli	0.556	0.444	0.000
E61.1 Iron deficiency	0.553	0.447	0.000
X10-X19 Contact with heat and hot substances	0.551	0.449	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.550	0.450	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.544	0.456	0.000
M89.8 Other specified disorders of bone	0.542	0.458	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.542	0.458	0.000
Y84.0 Cardiac catheterisation	0.542	0.458	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.542	0.458	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.540	0.459	0.000
V40-V49 Car occupant injured in transport accident	0.540	0.459	0.000
M86.9 Osteomyelitis, unspecified	0.539	0.461	0.000
Y35-Y36 Legal intervention and operations of war	0.538	0.462	0.000
Y10-Y34 Event of undetermined intent	0.538	0.462	0.000
X85-X99 Assault	0.538	0.462	0.000
X30-X39 Exposure to forces of nature	0.538	0.462	0.000
X00-X09 Exposure to smoke, fire and flames	0.538	0.462	0.000
W75-W84 Other accidental threats to breathing	0.538	0.462	0.000
W65-W74 Accidental drowning and submersion	0.538	0.462	0.000
V98-V99 Other and unspecified transport accidents	0.538	0.462	0.000
V95-V97 Air and space transport accidents	0.538	0.462	0.000
V90-V94 Water transport accidents	0.538	0.462	0.000
V70-V79 Bus occupant injured in transport accident	0.538	0.462	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.538	0.462	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.538	0.462	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.538	0.462	0.000
M21 Other acquired deformities of limbs	0.538	0.462	0.000
M35.7 Hypermobility syndrome	0.538	0.462	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.537	0.463	0.000
M90 Osteopathies in diseases classified elsewhere	0.537	0.463	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.535	0.464	0.000
M94 Other disorders of cartilage	0.535	0.465	0.000
W25.9 Unspecified place	0.534	0.466	0.000
M34 Systemic sclerosis	0.534	0.466	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.534	0.466	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.533	0.467	0.000
M10.0 Idiopathic gout	0.533	0.467	0.000
V10-V19 Pedal cyclist injured in transport accident	0.533	0.467	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.532	0.468	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.532	0.468	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.532	0.468	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.532	0.468	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.532	0.468	0.000
Y83.6 Removal of other organ (partial) (total)	0.531	0.469	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.530	0.470	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.530	0.470	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.526	0.474	0.000
W21 Striking against or struck by sports equipment	0.526	0.474	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.526	0.474	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.525	0.475	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.524	0.476	0.000
M79.70 Fibromyalgia (Multiple sites)	0.524	0.476	0.000
H90-H95 Other disorders of ear	0.524	0.476	0.000
M79.63 Pain in limb (Forearm)	0.523	0.477	0.000
L10-L14 Bullous disorders	0.523	0.477	0.000
M79.08 Rheumatism, unspecified (Other)	0.522	0.478	0.000
M76.9 Enthesopathy of lower limb, unspecified	0.522	0.478	0.000
M76.8 Other enthesopathies of lower limb, excluding foot	0.522	0.478	0.000
M76.7 Peroneal tendinitis	0.522	0.478	0.000
M76.5 Patellar tendinitis	0.522	0.478	0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]	0.522	0.478	0.000
M76.3 Iliotibial band syndrome	0.522	0.478	0.000
M76.2 Iliac crest spur	0.522	0.478	0.000
M76.1 Psoas tendinitis	0.522	0.478	0.000
M76.0 Gluteal tendinitis	0.522	0.478	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.520	0.480	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.520	0.480	0.000
M24.5 Contracture of joint	0.520	0.480	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.520	0.480	0.000
M93 Other osteochondropathies	0.519	0.481	0.000
W29 Contact with other powered hand tools and household machinery	0.518	0.482	0.000
M81.48 Drug-induced osteoporosis (Other)	0.518	0.482	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.518	0.482	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.518	0.482	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.518	0.482	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.518	0.482	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.518	0.482	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.518	0.482	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.518	0.482	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.518	0.482	0.000
M89.6 Osteopathy after poliomyelitis	0.517	0.482	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.517	0.482	0.000
M89.3 Hypertrophy of bone	0.517	0.482	0.000
M89.2 Other disorders of bone development and growth	0.517	0.482	0.000
M89.1 Epiphyseal arrest	0.517	0.482	0.000
H60 Otitis externa	0.517	0.483	0.000
M66.2 Spontaneous rupture of extensor tendons	0.517	0.483	0.000
W44 Foreign body entering into or through eye or natural orifice	0.517	0.483	0.000
M89.04 Algoneurodystrophy (Hand)	0.516	0.484	0.000
L60-L75 Disorders of skin appendages	0.516	0.484	0.000
Chapter XXII Codes for special purposes	0.516	0.484	0.000
M24.9 Joint derangement, unspecified	0.516	0.484	0.000
M24.6 Ankylosis of joint	0.516	0.484	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.516	0.484	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.516	0.484	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.515	0.485	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.513	0.486	0.000
M77 Other enthesopathies	0.513	0.487	0.000
Y00-Y09 Assault	0.512	0.488	0.000
E12.9 Without complications	0.512	0.488	0.000
E12.8 With unspecified complications	0.512	0.488	0.000
E12.7 With multiple complications	0.512	0.488	0.000
E12.6 With other specified complications	0.512	0.488	0.000
E12.5 With peripheral circulatory complications	0.512	0.488	0.000
E12.4 With neurological complications	0.512	0.488	0.000
E12.3 With ophthalmic complications	0.512	0.488	0.000
E12.2 With renal complications	0.512	0.488	0.000
E12.1 With ketoacidosis	0.512	0.488	0.000
E12.0 With coma	0.512	0.488	0.000
M72 Fibroblastic disorders	0.512	0.488	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.511	0.489	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.511	0.489	0.000
S91 Open wound of ankle and foot	0.511	0.489	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.510	0.489	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.510	0.489	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.510	0.489	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.510	0.489	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.510	0.489	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.510	0.489	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.510	0.489	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.510	0.489	0.000
X59 Exposure to unspecified factor	0.510	0.489	0.000
E14.3 With ophthalmic complications	0.510	0.490	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.510	0.490	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.509	0.490	0.000
M06.18 Adult-onset Still's disease (Other)	0.509	0.490	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.509	0.490	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.509	0.490	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.509	0.490	0.000
M06.14 Adult-onset Still's disease (Hand)	0.509	0.490	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.509	0.490	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.509	0.490	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.509	0.490	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.509	0.490	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.509	0.490	0.000
M06.28 Rheumatoid bursitis (Other)	0.509	0.490	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.509	0.490	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.509	0.490	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.509	0.490	0.000
M06.24 Rheumatoid bursitis (Hand)	0.509	0.490	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.509	0.490	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.509	0.490	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.509	0.490	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.509	0.490	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.509	0.490	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.509	0.490	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.509	0.490	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.509	0.490	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.509	0.490	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.509	0.490	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.509	0.490	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.509	0.490	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.509	0.490	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.509	0.490	0.000
M79.16 Myalgia (Lower leg)	0.509	0.490	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.509	0.491	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.507	0.493	0.000
X20-X29 Contact with venomous animals and plants	0.507	0.493	0.000
M79.62 Pain in limb (Upper arm)	0.507	0.493	0.000
M08.9 Juvenile arthritis, unspecified	0.506	0.494	0.000
M08.8 Other juvenile arthritis	0.506	0.494	0.000
M08.4 Pauciarticular juvenile arthritis	0.506	0.494	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.506	0.494	0.000
M08.2 Juvenile arthritis with systemic onset	0.506	0.494	0.000
M08.1 Juvenile ankylosing spondylitis	0.506	0.494	0.000
M08.0 Juvenile rheumatoid arthritis	0.506	0.494	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.506	0.494	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.506	0.494	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.506	0.494	0.000
M09.0 Juvenile arthritis in psoriasis	0.506	0.494	0.000
Y84.1 Kidney dialysis	0.505	0.495	0.000
E66 Obesity	0.504	0.496	0.000
W10 Fall on and from stairs and steps	0.504	0.496	0.000
M85.6 Other cyst of bone	0.504	0.496	0.000
M10.4 Other secondary gout	0.503	0.497	0.000
M10.3 Gout due to impairment of renal function	0.503	0.497	0.000
M10.2 Drug-induced gout	0.503	0.497	0.000
M10.1 Lead-induced gout	0.503	0.497	0.000
V80-V89 Other land transport accidents	0.501	0.499	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.499	0.501	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.498	0.502	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.498	0.502	0.000
M14.4 Arthropathy in amyloidosis	0.498	0.502	0.000
M14.3 Lipoid dermatoarthritis	0.498	0.502	0.000
M14.2 Diabetic arthropathy	0.498	0.502	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.498	0.502	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.498	0.502	0.000
E11.1 With ketoacidosis	0.498	0.502	0.001
S92 Fracture of foot, except ankle	0.498	0.502	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations