TreeWAS – Variant ID: rs10954668

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E23 Hypofunction and other disorders of pituitary gland	0.042	0.958	0.000
E23.6 Other disorders of pituitary gland	0.041	0.959	0.000
E20-E35 Disorders of other endocrine glands	0.040	0.960	0.000
E27 Other disorders of adrenal gland	0.040	0.960	0.000
E27.8 Other specified disorders of adrenal gland	0.039	0.961	0.000
E24 Cushing's syndrome	0.039	0.961	0.000
E23.0 Hypopituitarism	0.037	0.963	0.000
E24.9 Cushing's syndrome, unspecified	0.036	0.964	0.000
E27.1 Primary adrenocortical insufficiency	0.035	0.965	0.000
E27.2 Addisonian crisis	0.035	0.965	0.000
E23.2 Diabetes insipidus	0.035	0.965	0.000
E34 Other endocrine disorders	0.035	0.965	0.000
E22 Hyperfunction of pituitary gland	0.034	0.966	0.000
E28 Ovarian dysfunction	0.033	0.967	0.000
E24.2 Drug-induced Cushing's syndrome	0.032	0.968	0.000
E31 Polyglandular dysfunction	0.031	0.969	0.000
E24.0 Pituitary-dependent Cushing's disease	0.030	0.970	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.030	0.970	0.000
E23.1 Drug-induced hypopituitarism	0.030	0.970	0.000
E24.8 Other Cushing's syndrome	0.030	0.970	0.000
E23.7 Disorder of pituitary gland, unspecified	0.030	0.970	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.029	0.971	0.000
E32 Diseases of thymus	0.029	0.971	0.000
E30 Disorders of puberty, not elsewhere classified	0.029	0.971	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.029	0.971	0.000
E22.1 Hyperprolactinaemia	0.029	0.971	0.000
E27.5 Adrenomedullary hyperfunction	0.029	0.971	0.000
E27.0 Other adrenocortical overactivity	0.029	0.971	0.000
E34.9 Endocrine disorder, unspecified	0.029	0.971	0.000
E34.0 Carcinoid syndrome	0.028	0.972	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.028	0.972	0.000
E24.3 Ectopic ACTH syndrome	0.028	0.972	0.000
E24.1 Nelson's syndrome	0.028	0.972	0.000
H54.4 Blindness, one eye	0.028	0.972	0.000
E20 Hypoparathyroidism	0.028	0.972	0.000
E28.2 Polycystic ovarian syndrome	0.027	0.973	0.000
E22.0 Acromegaly and pituitary gigantism	0.027	0.973	0.000
E34.8 Other specified endocrine disorders	0.027	0.973	0.000
E25 Adrenogenital disorders	0.027	0.973	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.026	0.974	0.000
E34.5 Androgen resistance syndrome	0.025	0.975	0.000
E34.4 Constitutional tall stature	0.025	0.975	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.025	0.975	0.000
E34.1 Other hypersecretion of intestinal hormones	0.025	0.975	0.000
E34.3 Short stature, not elsewhere classified	0.025	0.975	0.000
E22.8 Other hyperfunction of pituitary gland	0.024	0.976	0.000
E31.0 Autoimmune polyglandular failure	0.024	0.976	0.000
E28.9 Ovarian dysfunction, unspecified	0.024	0.976	0.000
E28.8 Other ovarian dysfunction	0.024	0.976	0.000
E28.1 Androgen excess	0.024	0.976	0.000
E28.0 Oestrogen excess	0.024	0.976	0.000
E28.3 Primary ovarian failure	0.023	0.976	0.000
E29 Testicular dysfunction	0.023	0.977	0.000
E26 Hyperaldosteronism	0.023	0.977	0.000
E31.9 Polyglandular dysfunction, unspecified	0.022	0.978	0.000
E31.8 Other polyglandular dysfunction	0.022	0.978	0.000
E31.1 Polyglandular hyperfunction	0.022	0.978	0.000
E30.9 Disorder of puberty, unspecified	0.021	0.979	0.000
E30.8 Other disorders of puberty	0.021	0.979	0.000
E30.1 Precocious puberty	0.021	0.979	0.000
E30.0 Delayed puberty	0.021	0.979	0.000
E32.9 Disease of thymus, unspecified	0.021	0.979	0.000
E32.8 Other diseases of thymus	0.021	0.979	0.000
E32.1 Abscess of thymus	0.021	0.979	0.000
E32.0 Persistent hyperplasia of thymus	0.021	0.979	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.021	0.979	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.021	0.979	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.021	0.979	0.000
E27.9 Disorder of adrenal gland, unspecified	0.020	0.980	0.000
E20.8 Other hypoparathyroidism	0.020	0.980	0.000
E20.1 Pseudohypoparathyroidism	0.020	0.980	0.000
E20.0 Idiopathic hypoparathyroidism	0.020	0.980	0.000
E25.9 Adrenogenital disorder, unspecified	0.019	0.981	0.000
E25.8 Other adrenogenital disorders	0.019	0.981	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.019	0.981	0.000
E20.9 Hypoparathyroidism, unspecified	0.018	0.981	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.017	0.983	0.000
E29.9 Testicular dysfunction, unspecified	0.017	0.983	0.000
E29.8 Other testicular dysfunction	0.017	0.983	0.000
E29.0 Testicular hyperfunction	0.017	0.983	0.000
E26.8 Other hyperaldosteronism	0.016	0.983	0.000
E26.1 Secondary hyperaldosteronism	0.016	0.983	0.000
E26.9 Hyperaldosteronism, unspecified	0.016	0.984	0.000
K31.8 Other specified diseases of stomach and duodenum	0.000	0.987	0.013
Z45.8 Adjustment and management of other implanted devices	0.013	0.987	0.000
N76.0 Acute vaginitis	0.013	0.987	0.000
N76.2 Acute vulvitis	0.013	0.987	0.000
N76 Other inflammation of vagina and vulva	0.012	0.988	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.011	0.988	0.000
E26.0 Primary hyperaldosteronism	0.011	0.989	0.000
E29.1 Testicular hypofunction	0.011	0.989	0.000
N76.3 Subacute and chronic vulvitis	0.011	0.989	0.000
N76.8 Other specified inflammation of vagina and vulva	0.011	0.989	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.989	0.011
N76.6 Ulceration of vulva	0.010	0.990	0.000
N76.1 Subacute and chronic vaginitis	0.010	0.990	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.991	0.009
Q23.1 Congenital insufficiency of aortic valve	0.009	0.991	0.000
Z90.3 Acquired absence of part of stomach	0.009	0.991	0.000
Q61.3 Polycystic kidney, unspecified	0.008	0.992	0.000
N76.5 Ulceration of vagina	0.008	0.992	0.000
C16.2 Body of stomach	0.008	0.992	0.000
C16.9 Stomach, unspecified	0.008	0.992	0.000
Q61 Cystic kidney disease	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.007	0.993	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.993	0.007
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.007	0.993	0.000
N76.4 Abscess of vulva	0.007	0.993	0.000
Q61.5 Medullary cystic kidney	0.007	0.993	0.000
Q23 Congenital malformations of aortic and mitral valves	0.007	0.993	0.000
C16.0 Cardia	0.007	0.993	0.000
Q61.2 Polycystic kidney, adult type	0.007	0.993	0.000
S67 Crushing injury of wrist and hand	0.000	0.993	0.007
C16.3 Pyloric antrum	0.007	0.993	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.993	0.007
H54 Blindness and low vision	0.007	0.993	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.993	0.007
M10.9 Gout, unspecified	0.000	0.994	0.006
Q61.9 Cystic kidney disease, unspecified	0.006	0.994	0.000
C16.4 Pylorus	0.006	0.994	0.000
C16.6 Greater curvature of stomach, unspecified	0.006	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.006	0.994	0.000
Q23.0 Congenital stenosis of aortic valve	0.006	0.994	0.000
Q61.8 Other cystic kidney diseases	0.005	0.994	0.000
Q61.1 Polycystic kidney, infantile type	0.005	0.994	0.000
C16.8 Overlapping lesion of stomach	0.005	0.994	0.000
Q61.4 Renal dysplasia	0.005	0.995	0.000
H54.6 Unqualified visual loss, one eye	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.005	0.995	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.995	0.005
E21.2 Other hyperparathyroidism	0.005	0.995	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.005	0.995	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q23.4 Hypoplastic left heart syndrome	0.005	0.995	0.000
Q23.2 Congenital mitral stenosis	0.005	0.995	0.000
H54.5 Low vision, one eye	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
Q60.0 Renal agenesis, unilateral	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
H54.3 Unqualified visual loss, both eyes	0.005	0.995	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.995	0.005
M10.93 Gout, unspecified (Forearm)	0.000	0.995	0.005
Q23.3 Congenital mitral insufficiency	0.005	0.995	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.005	0.995	0.000
L60.2 Onychogryphosis	0.000	0.995	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.995	0.005
E21.5 Disorder of parathyroid gland, unspecified	0.005	0.995	0.000
M10.98 Gout, unspecified (Other)	0.000	0.995	0.005
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
M10.92 Gout, unspecified (Upper arm)	0.000	0.995	0.005
M10.91 Gout, unspecified (Shoulder region)	0.000	0.995	0.005
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.995	0.005
M10.94 Gout, unspecified (Hand)	0.000	0.995	0.005
C16.1 Fundus of stomach	0.005	0.995	0.000
H54.1 Blindness, one eye, low vision, other eye	0.005	0.995	0.000
H54.7 Unspecified visual loss	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.004	0.995	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.996	0.004
Q62.2 Congenital megaloureter	0.004	0.996	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
S64 Injury of nerves at wrist and hand level	0.000	0.996	0.004
M10.96 Gout, unspecified (Lower leg)	0.000	0.996	0.004
H54.2 Low vision, both eyes	0.004	0.996	0.000
S65.5 Injury of blood vessel(s) of other finger	0.000	0.996	0.004
L60.0 Ingrowing nail	0.000	0.996	0.004
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.996	0.004
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
M10 Gout	0.000	0.996	0.004
S60-S69 Injuries to the wrist and hand	0.000	0.996	0.004
H54.9 Unspecified visual impairment (binocular)	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
S65 Injury of blood vessels at wrist and hand level	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
M10.90 Gout, unspecified (Multiple sites)	0.000	0.996	0.004
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.996	0.004
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.996	0.004
S64.1 Injury of median nerve at wrist and hand level	0.000	0.996	0.004
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.004	0.996	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.996	0.004
M06.9 Rheumatoid arthritis, unspecified	0.000	0.996	0.004
M21.1 Varus deformity, not elsewhere classified	0.000	0.996	0.004
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.996	0.004
M06 Other rheumatoid arthritis	0.000	0.996	0.004
L60 Nail disorders	0.000	0.996	0.004
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.996	0.004
C16.5 Lesser curvature of stomach, unspecified	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
Z54.0 Convalescence following surgery	0.000	0.996	0.004
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
L60.8 Other nail disorders	0.000	0.996	0.004
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.004	0.996	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.996	0.004
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.996	0.004
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.996	0.004
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.996	0.004
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.996	0.004
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.996	0.004
M21.3 Wrist or foot drop (acquired)	0.000	0.996	0.004
Q25.1 Coarctation of aorta	0.004	0.996	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.996	0.004
S64.4 Injury of digital nerve of other finger	0.000	0.996	0.004
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.996	0.004
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.996	0.004
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.996	0.004
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.996	0.004
Z35.5 Supervision of elderly primigravida	0.004	0.996	0.000
Z81.8 Family history of other mental and behavioural disorders	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
S69 Other and unspecified injuries of wrist and hand	0.000	0.996	0.004
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.003	0.996	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.996	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.996	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.996	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.996	0.000
Q64.4 Malformation of urachus	0.003	0.996	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.996	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.996	0.000
Q64.0 Epispadias	0.003	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.996	0.000
Q96 Turner's syndrome	0.003	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.997	0.003
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
F22.0 Delusional disorder	0.000	0.997	0.003
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.997	0.003
S64.8 Injury of other nerves at wrist and hand level	0.000	0.997	0.003
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.997	0.003
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
M10.4 Other secondary gout	0.000	0.997	0.003
M10.3 Gout due to impairment of renal function	0.000	0.997	0.003
M10.2 Drug-induced gout	0.000	0.997	0.003
M10.1 Lead-induced gout	0.000	0.997	0.003
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.997	0.003
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.997	0.003
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.997	0.003
S65.4 Injury of blood vessel(s) of thumb	0.000	0.997	0.003
S65.3 Injury of deep palmar arch	0.000	0.997	0.003
S65.2 Injury of superficial palmar arch	0.000	0.997	0.003
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
C02.1 Border of tongue	0.003	0.997	0.000
M10.0 Idiopathic gout	0.000	0.997	0.003
Q25.3 Stenosis of aorta	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.997	0.003
S69.8 Other specified injuries of wrist and hand	0.000	0.997	0.003
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.997	0.003
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.997	0.003
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.997	0.003
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M21 Other acquired deformities of limbs	0.000	0.997	0.003
M06.2 Rheumatoid bursitis	0.000	0.997	0.003
M06.1 Adult-onset Still's disease	0.000	0.997	0.003
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.003	0.997	0.000
L60.5 Yellow nail syndrome	0.000	0.997	0.003
L60.4 Beau's lines	0.000	0.997	0.003
L60.1 Onycholysis	0.000	0.997	0.003
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
N39.8 Other specified disorders of urinary system	0.000	0.997	0.003
Q21.0 Ventricular septal defect	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q31.0 Web of larynx	0.003	0.997	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.997	0.003
M06.8 Other specified rheumatoid arthritis	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.997	0.003
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
Q44.6 Cystic disease of liver	0.003	0.997	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.997	0.003
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.997	0.003
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.997	0.003
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.997	0.003
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.997	0.003
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.997	0.003
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.997	0.003
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.997	0.003
M21.4 Flat foot [pes planus] (acquired)	0.000	0.997	0.003
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.003
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
Q24.0 Dextrocardia	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.997	0.003
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.997	0.003
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Z39.0 Care and examination immediately after delivery	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
L60.9 Nail disorder, unspecified	0.000	0.997	0.003
Q67.6 Pectus excavatum	0.003	0.997	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.997	0.003
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.997	0.003
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.997	0.003
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
I95.2 Hypotension due to drugs	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
M10.09 Idiopathic gout (Site unspecified)	0.000	0.997	0.003
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q96.8 Other variants of Turner's syndrome	0.003	0.997	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.003	0.997	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.003	0.997	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.003	0.997	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.003	0.997	0.000
Q96.0 Karyotype 45,X	0.003	0.997	0.000
S63.0 Dislocation of wrist	0.000	0.997	0.003
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.997	0.003
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.997	0.003
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.997	0.003
M21.9 Acquired deformity of limb, unspecified	0.000	0.997	0.003
S63.5 Sprain and strain of wrist	0.000	0.997	0.003
T40.4 Other synthetic narcotics	0.003	0.997	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.997	0.003
M21.8 Other specified acquired deformities of limbs	0.000	0.997	0.003
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.997	0.003
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.997	0.003
S68.4 Traumatic amputation of hand at wrist level	0.000	0.997	0.003
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.997	0.003
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.997	0.003
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.997	0.003
Q25.4 Other congenital malformations of aorta	0.002	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.997	0.003
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.002	0.997	0.000
M10.19 Lead-induced gout (Site unspecified)	0.000	0.997	0.002
M10.18 Lead-induced gout (Other)	0.000	0.997	0.002
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.997	0.002
M10.16 Lead-induced gout (Lower leg)	0.000	0.997	0.002
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.14 Lead-induced gout (Hand)	0.000	0.997	0.002
M10.13 Lead-induced gout (Forearm)	0.000	0.997	0.002
M10.12 Lead-induced gout (Upper arm)	0.000	0.997	0.002
M10.11 Lead-induced gout (Shoulder region)	0.000	0.997	0.002
M10.10 Lead-induced gout (Multiple sites)	0.000	0.997	0.002
M10.29 Drug-induced gout (Site unspecified)	0.000	0.997	0.002
M10.28 Drug-induced gout (Other)	0.000	0.997	0.002
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.997	0.002
M10.26 Drug-induced gout (Lower leg)	0.000	0.997	0.002
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.24 Drug-induced gout (Hand)	0.000	0.997	0.002
M10.23 Drug-induced gout (Forearm)	0.000	0.997	0.002
M10.22 Drug-induced gout (Upper arm)	0.000	0.997	0.002
M10.21 Drug-induced gout (Shoulder region)	0.000	0.997	0.002
M10.20 Drug-induced gout (Multiple sites)	0.000	0.997	0.002
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.997	0.002
M10.38 Gout due to impairment of renal function (Other)	0.000	0.997	0.002
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.997	0.002
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.997	0.002
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.997	0.002
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.997	0.002
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.997	0.002
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.997	0.002
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.997	0.002
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.997	0.002
M10.49 Other secondary gout (Site unspecified)	0.000	0.997	0.002
M10.48 Other secondary gout (Other)	0.000	0.997	0.002
M10.47 Other secondary gout (Ankle and foot)	0.000	0.997	0.002
M10.46 Other secondary gout (Lower leg)	0.000	0.997	0.002
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.44 Other secondary gout (Hand)	0.000	0.997	0.002
M10.43 Other secondary gout (Forearm)	0.000	0.997	0.002
M10.42 Other secondary gout (Upper arm)	0.000	0.997	0.002
M10.41 Other secondary gout (Shoulder region)	0.000	0.997	0.002
M10.40 Other secondary gout (Multiple sites)	0.000	0.997	0.002
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.000	0.997	0.003
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.997	0.003
L60.3 Nail dystrophy	0.000	0.997	0.002
D10 Benign neoplasm of mouth and pharynx	0.000	0.997	0.003
Q90 Down's syndrome	0.002	0.997	0.000
Q11.1 Other anophthalmos	0.003	0.997	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.002	0.997	0.000
Q31.8 Other congenital malformations of larynx	0.002	0.997	0.000
Q31.5 Congenital laryngomalacia	0.002	0.997	0.000
Q31.4 Congenital laryngeal stridor	0.002	0.997	0.000
Q31.3 Laryngocele	0.002	0.997	0.000
Q31.2 Laryngeal hypoplasia	0.002	0.997	0.000
Q31.1 Congenital subglottic stenosis	0.002	0.997	0.000
S65.1 Injury of radial artery at wrist and hand level	0.000	0.997	0.002
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.997	0.003
M10.00 Idiopathic gout (Multiple sites)	0.000	0.997	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.997	0.000
Q21.2 Atrioventricular septal defect	0.002	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.997	0.000
M10.08 Idiopathic gout (Other)	0.000	0.997	0.002
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.04 Idiopathic gout (Hand)	0.000	0.997	0.002
M10.03 Idiopathic gout (Forearm)	0.000	0.997	0.002
M10.02 Idiopathic gout (Upper arm)	0.000	0.997	0.002
M10.01 Idiopathic gout (Shoulder region)	0.000	0.997	0.002
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.002
M05 Seropositive rheumatoid arthritis	0.000	0.997	0.002
Q12 Congenital lens malformations	0.002	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
M12 Other specific arthropathies	0.000	0.997	0.003
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q78 Other osteochondrodysplasias	0.002	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations