TreeWAS – Variant ID: rs10974944

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D47.1 Chronic myeloproliferative disease	1.000	0.000	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
D45 Polycythaemia vera	1.000	0.000	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	1.000	0.000	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	1.000	0.000	0.000
D47.4 Osteomyelofibrosis	0.983	0.017	0.000
D46 Myelodysplastic syndromes	0.980	0.020	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.962	0.038	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.960	0.040	0.000
D47.2 Monoclonal gammopathy	0.925	0.075	0.000
K50.9 Crohn's disease, unspecified	0.911	0.089	0.000
K50 Crohn's disease [regional enteritis]	0.908	0.092	0.000
K50.0 Crohn's disease of small intestine	0.887	0.113	0.000
K50.1 Crohn's disease of large intestine	0.873	0.127	0.000
D37.7 Other digestive organs	0.858	0.142	0.000
D37.4 Colon	0.838	0.162	0.000
D37.9 Digestive organ, unspecified	0.827	0.173	0.000
K50.8 Other Crohn's disease	0.817	0.183	0.000
D37.5 Rectum	0.762	0.238	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.761	0.239	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.745	0.255	0.000
D46.4 Refractory anaemia, unspecified	0.740	0.260	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.736	0.264	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.717	0.283	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.717	0.283	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.717	0.283	0.000
D37.3 Appendix	0.712	0.287	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.709	0.291	0.000
D46.7 Other myelodysplastic syndromes	0.703	0.297	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.703	0.297	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.703	0.297	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.703	0.297	0.000
D37.1 Stomach	0.700	0.300	0.000
D46.2 Refractory anaemia with excess of blasts	0.699	0.301	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.676	0.324	0.000
D46.1 Refractory anaemia with sideroblasts	0.673	0.327	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.649	0.351	0.000
D37.2 Small intestine	0.648	0.352	0.000
D37.6 Liver, gallbladder and bile ducts	0.640	0.360	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.620	0.380	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.607	0.393	0.000
D43.4 Spinal cord	0.572	0.428	0.000
D37.0 Lip, oral cavity and pharynx	0.549	0.451	0.000
D43.1 Brain, infratentorial	0.549	0.451	0.000
D43.9 Central nervous system, unspecified	0.534	0.466	0.000
D43.7 Other parts of central nervous system	0.534	0.466	0.000
D43.3 Cranial nerves	0.534	0.466	0.000
D43.0 Brain, supratentorial	0.527	0.473	0.000
D39.1 Ovary	0.520	0.480	0.000
D38.5 Other respiratory organs	0.516	0.483	0.000
D43.2 Brain, unspecified	0.515	0.485	0.000
D42.9 Meninges, unspecified	0.514	0.486	0.000
D42.1 Spinal meninges	0.514	0.486	0.000
D42.0 Cerebral meninges	0.514	0.486	0.000
D39.9 Female genital organ, unspecified	0.485	0.515	0.000
D39.7 Other female genital organs	0.485	0.515	0.000
D39.2 Placenta	0.485	0.515	0.000
D38.0 Larynx	0.468	0.532	0.000
D44.0 Thyroid gland	0.466	0.534	0.000
D38.6 Respiratory organ, unspecified	0.465	0.534	0.000
D38.4 Thymus	0.465	0.534	0.000
D38.3 Mediastinum	0.465	0.534	0.000
D38.2 Pleura	0.465	0.534	0.000
D44.7 Aortic body and other paraganglia	0.456	0.543	0.000
D44.9 Endocrine gland, unspecified	0.455	0.544	0.000
D44.8 Pluriglandular involvement	0.446	0.554	0.000
D44.5 Pineal gland	0.444	0.556	0.000
D44.2 Parathyroid gland	0.444	0.556	0.000
D44.4 Craniopharyngeal duct	0.441	0.558	0.000
D40.9 Male genital organ, unspecified	0.435	0.564	0.000
D40.7 Other male genital organs	0.435	0.564	0.000
D44.6 Carotid body	0.422	0.578	0.000
D40.1 Testis	0.419	0.581	0.000
D44.1 Adrenal gland	0.419	0.581	0.000
D39.0 Uterus	0.391	0.608	0.000
D40.0 Prostate	0.350	0.649	0.000
D44.3 Pituitary gland	0.344	0.655	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.307	0.693	0.000
D38.1 Trachea, bronchus and lung	0.296	0.703	0.000
D41.2 Ureter	0.234	0.766	0.000
D41.9 Urinary organ, unspecified	0.220	0.780	0.000
D41.7 Other urinary organs	0.220	0.780	0.000
D41.3 Urethra	0.220	0.780	0.000
D41.1 Renal pelvis	0.220	0.780	0.000
K50-K52 Noninfective enteritis and colitis	0.207	0.793	0.000
D75.1 Secondary polycythaemia	0.196	0.804	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.194	0.806	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.833	0.167
D75 Other diseases of blood and blood-forming organs	0.158	0.842	0.000
K52 Other non-infective gastro-enteritis and colitis	0.149	0.851	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.143	0.857	0.000
D48.4 Peritoneum	0.139	0.861	0.000
D48.3 Retroperitoneum	0.139	0.861	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.139	0.861	0.000
D75.0 Familial erythrocytosis	0.136	0.864	0.000
D48.7 Other specified sites	0.125	0.875	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.124	0.876	0.000
D48.0 Bone and articular cartilage	0.122	0.878	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.120	0.880	0.000
K52.3 Indeterminate colitis	0.119	0.881	0.000
D75.2 Essential thrombocytosis	0.115	0.885	0.000
D86 Sarcoidosis	0.114	0.886	0.000
D86.0 Sarcoidosis of lung	0.111	0.889	0.000
D48.5 Skin	0.108	0.892	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.107	0.892	0.000
D80-D89 Certain disorders involving the immune mechanism	0.107	0.893	0.000
D41.0 Kidney	0.106	0.894	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.105	0.895	0.000
D86.9 Sarcoidosis, unspecified	0.102	0.898	0.000
D86.8 Sarcoidosis of other and combined sites	0.100	0.900	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.100	0.900	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.099	0.901	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.098	0.902	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.098	0.902	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.097	0.903	0.000
D86.1 Sarcoidosis of lymph nodes	0.096	0.904	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.092	0.908	0.000
D73 Diseases of spleen	0.092	0.908	0.000
K52.1 Toxic gastro-enteritis and colitis	0.088	0.912	0.000
D69 Purpura and other haemorrhagic conditions	0.088	0.912	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.086	0.914	0.000
D74 Methaemoglobinaemia	0.086	0.914	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.086	0.914	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.086	0.914	0.000
D48.6 Breast	0.085	0.915	0.000
D84 Other immunodeficiencies	0.085	0.915	0.000
D76.3 Other histiocytosis syndromes	0.085	0.915	0.000
D55-D59 Haemolytic anaemias	0.082	0.918	0.000
D69.6 Thrombocytopenia, unspecified	0.078	0.922	0.000
D82 Immunodeficiency associated with other major defects	0.077	0.923	0.000
D81 Combined immunodeficiencies	0.077	0.923	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.077	0.923	0.000
D73.0 Hyposplenism	0.076	0.924	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.924	0.076
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.925	0.075
D83 Common variable immunodeficiency	0.074	0.926	0.000
D73.3 Abscess of spleen	0.073	0.927	0.000
D69.5 Secondary thrombocytopenia	0.073	0.927	0.000
D48.1 Connective and other soft tissue	0.072	0.928	0.000
D73.8 Other diseases of spleen	0.072	0.928	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.071	0.929	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.071	0.929	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.071	0.929	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.071	0.929	0.000
D84.1 Defects in the complement system	0.071	0.929	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.930	0.070
S22.30 Fracture of rib (closed)	0.000	0.930	0.070
D86.3 Sarcoidosis of skin	0.068	0.932	0.000
D66 Hereditary factor VIII deficiency	0.068	0.932	0.000
D59 Acquired haemolytic anaemia	0.067	0.933	0.000
D67 Hereditary factor IX deficiency	0.066	0.934	0.000
D73.9 Disease of spleen, unspecified	0.066	0.934	0.000
D73.2 Chronic congestive splenomegaly	0.066	0.934	0.000
D56 Thalassaemia	0.066	0.934	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.934	0.066
K51 Ulcerative colitis	0.066	0.934	0.000
D69.9 Haemorrhagic condition, unspecified	0.064	0.936	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.063	0.937	0.000
D69.8 Other specified haemorrhagic conditions	0.063	0.937	0.000
D69.1 Qualitative platelet defects	0.063	0.937	0.000
Z71.8 Other specified counselling	0.000	0.938	0.062
D74.9 Methaemoglobinaemia, unspecified	0.062	0.938	0.000
D74.8 Other methaemoglobinaemias	0.062	0.938	0.000
D74.0 Congenital methaemoglobinaemia	0.062	0.938	0.000
D73.5 Infarction of spleen	0.061	0.939	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.939	0.061
D84.8 Other specified immunodeficiencies	0.061	0.939	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.061	0.939	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.939	0.061
D69.2 Other nonthrombocytopenic purpura	0.061	0.939	0.000
D89.1 Cryoglobulinaemia	0.061	0.939	0.000
D80 Immunodeficiency with predominantly antibody defects	0.060	0.940	0.000
D69.0 Allergic purpura	0.059	0.941	0.000
D57 Sickle-cell disorders	0.059	0.941	0.000
D55 Anaemia due to enzyme disorders	0.059	0.941	0.000
D84.9 Immunodeficiency, unspecified	0.058	0.941	0.000
D69.4 Other primary thrombocytopenia	0.058	0.941	0.000
K51.9 Ulcerative colitis, unspecified	0.058	0.942	0.000
D70 Agranulocytosis	0.057	0.943	0.000
D73.1 Hypersplenism	0.057	0.943	0.000
D73.4 Cyst of spleen	0.056	0.944	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.055	0.944	0.000
D81.9 Combined immunodeficiency, unspecified	0.055	0.945	0.000
D81.8 Other combined immunodeficiencies	0.055	0.945	0.000
D81.7 Major histocompatibility complex class II deficiency	0.055	0.945	0.000
D81.6 Major histocompatibility complex class I deficiency	0.055	0.945	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.055	0.945	0.000
D81.4 Nezelof's syndrome	0.055	0.945	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.055	0.945	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.055	0.945	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.055	0.945	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.055	0.945	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.055	0.945	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.055	0.945	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.055	0.945	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.055	0.945	0.000
D82.2 Immunodeficiency with short-limbed stature	0.055	0.945	0.000
D82.1 Di George's syndrome	0.055	0.945	0.000
D82.0 Wiskott-Aldrich syndrome	0.055	0.945	0.000
D72 Other disorders of white blood cells	0.055	0.945	0.000
D56.1 Beta thalassaemia	0.053	0.947	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.053	0.947	0.000
D83.8 Other common variable immunodeficiencies	0.053	0.947	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.053	0.947	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.053	0.947	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.053	0.947	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.053	0.947	0.000
D59.1 Other autoimmune haemolytic anaemias	0.052	0.948	0.000
D89.3 Immune reconstitution syndrome	0.051	0.949	0.000
K51.8 Other ulcerative colitis	0.051	0.949	0.000
D68 Other coagulation defects	0.051	0.949	0.000
D41.4 Bladder	0.050	0.950	0.000
D83.9 Common variable immunodeficiency, unspecified	0.050	0.950	0.000
D68.5 Primary Thrombophilia	0.050	0.950	0.000
D56.3 Thalassaemia trait	0.049	0.951	0.000
D59.8 Other acquired haemolytic anaemias	0.048	0.952	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.048	0.952	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.048	0.952	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.048	0.952	0.000
D59.3 Haemolytic-uraemic syndrome	0.048	0.952	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.048	0.952	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.048	0.952	0.000
D56.9 Thalassaemia, unspecified	0.047	0.952	0.000
D56.8 Other thalassaemias	0.047	0.952	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.047	0.952	0.000
D56.2 Delta-beta thalassaemia	0.047	0.952	0.000
D56.0 Alpha thalassaemia	0.047	0.952	0.000
D58 Other hereditary haemolytic anaemias	0.047	0.953	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.045	0.955	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.044	0.955	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.956	0.044
D80.8 Other immunodeficiencies with predominantly antibody defects	0.043	0.957	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.043	0.957	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.043	0.957	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.043	0.957	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.043	0.957	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.043	0.957	0.000
D57.1 Sickle-cell anaemia without crisis	0.042	0.957	0.000
D57.8 Other sickle-cell disorders	0.042	0.957	0.000
D57.3 Sickle-cell trait	0.042	0.957	0.000
D57.2 Double heterozygous sickling disorders	0.042	0.957	0.000
D57.0 Sickle-cell anaemia with crisis	0.042	0.957	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.957	0.042
D55.9 Anaemia due to enzyme disorder, unspecified	0.042	0.957	0.000
D55.8 Other anaemias due to enzyme disorders	0.042	0.957	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.042	0.957	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.042	0.957	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.042	0.957	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.042	0.957	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.958	0.042
D68.1 Hereditary factor XI deficiency	0.042	0.958	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.041	0.958	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.041	0.959	0.000
D50-D53 Nutritional anaemias	0.041	0.959	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.040	0.960	0.000
D72.9 Disorder of white blood cells, unspecified	0.039	0.960	0.000
D72.0 Genetic anomalies of leukocytes	0.039	0.960	0.000
Z71.2 Person consulting for explanation of investigation findings	0.000	0.962	0.038
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.037	0.963	0.000
D68.4 Acquired coagulation factor deficiency	0.037	0.963	0.000
K51.4 Pseudopolyposis of colon	0.036	0.964	0.000
S22.3 Fracture of rib	0.000	0.964	0.036
Z71.6 Tobacco abuse counselling	0.000	0.965	0.035
D80.1 Nonfamilial hypogammaglobulinaemia	0.035	0.965	0.000
Z34 Supervision of normal pregnancy	0.000	0.966	0.034
D58.8 Other specified hereditary haemolytic anaemias	0.034	0.966	0.000
D58.2 Other haemoglobinopathies	0.034	0.966	0.000
D58.1 Hereditary elliptocytosis	0.034	0.966	0.000
D68.8 Other specified coagulation defects	0.034	0.966	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.033	0.967	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.967	0.033
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.968	0.032
D53 Other nutritional anaemias	0.031	0.969	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.969	0.031
Z71.3 Dietary counselling and surveillance	0.000	0.969	0.031
D58.9 Hereditary haemolytic anaemia, unspecified	0.030	0.969	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.970	0.030
Z71.5 Drug abuse counselling and surveillance	0.000	0.970	0.030
Z71.0 Person consulting on behalf of another person	0.000	0.970	0.030
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.030	0.970	0.000
D68.0 Von Willebrand's disease	0.029	0.971	0.000
D52 Folate deficiency anaemia	0.028	0.972	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.972	0.028
K51.2 Ulcerative (chronic) proctitis	0.028	0.972	0.000
D68.9 Coagulation defect, unspecified	0.028	0.972	0.000
D72.8 Other specified disorders of white blood cells	0.028	0.972	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.028	0.972	0.000
D68.6 Other Thrombophilia	0.028	0.972	0.000
D72.1 Eosinophilia	0.028	0.972	0.000
K51.5 Mucosal proctocolitis	0.027	0.972	0.000
D58.0 Hereditary spherocytosis	0.026	0.973	0.000
D51 Vitamin B12 deficiency anaemia	0.027	0.973	0.000
S22.31 Fracture of rib (open)	0.000	0.974	0.026
W29.9 Unspecified place	0.025	0.975	0.000
D53.9 Nutritional anaemia, unspecified	0.024	0.976	0.000
D53.8 Other specified nutritional anaemias	0.022	0.977	0.000
D53.2 Scorbutic anaemia	0.022	0.977	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.022	0.977	0.000
D53.0 Protein deficiency anaemia	0.022	0.977	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.022	0.978	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.978	0.022
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.979	0.021
D52.8 Other folate deficiency anaemias	0.020	0.979	0.000
D52.1 Drug-induced folate deficiency anaemia	0.020	0.979	0.000
D52.0 Dietary folate deficiency anaemia	0.020	0.979	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.980	0.019
Z45.2 Adjustment and management of vascular access device	0.019	0.981	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.019	0.981	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.019	0.981	0.000
D51.2 Transcobalamin II deficiency	0.019	0.981	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.019	0.981	0.000
D52.9 Folate deficiency anaemia, unspecified	0.019	0.981	0.000
Z71.9 Counselling, unspecified	0.000	0.984	0.015
H60.9 Otitis externa, unspecified	0.014	0.986	0.000
D68.2 Hereditary deficiency of other clotting factors	0.014	0.986	0.000
H60 Otitis externa	0.012	0.988	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.988	0.012
H60.5 Acute otitis externa, non-infective	0.011	0.989	0.000
S22.5 Flail chest	0.000	0.989	0.011
H00.1 Chalazion	0.011	0.989	0.000
D60-D64 Aplastic and other anaemias	0.011	0.989	0.000
W29 Contact with other powered hand tools and household machinery	0.011	0.989	0.000
S22.50 Flail chest (closed)	0.000	0.990	0.010
H60.8 Other otitis externa	0.010	0.990	0.000
H60.4 Cholesteatoma of external ear	0.010	0.990	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.010	0.990	0.000
H60.1 Cellulitis of external ear	0.009	0.990	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.991	0.009
H60.0 Abscess of external ear	0.009	0.991	0.000
Z93.5 Cystostomy status	0.009	0.991	0.000
Z93.2 Ileostomy status	0.009	0.991	0.000
H60.2 Malignant otitis externa	0.009	0.991	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.991	0.009
S22.8 Fracture of other parts of bony thorax	0.000	0.991	0.009
S22.51 Flail chest (open)	0.000	0.992	0.008
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.008	0.992	0.000
W29.8 Other specified place	0.008	0.992	0.000
W29.6 Industrial and construction area	0.008	0.992	0.000
W29.0 Home	0.008	0.992	0.000
W29.7 Farm	0.008	0.992	0.000
W29.4 Street and highway	0.008	0.992	0.000
W29.3 Sports and athletics area	0.008	0.992	0.000
W29.2 School, other institution and public administrative area	0.008	0.992	0.000
W29.1 Residential institution	0.008	0.992	0.000
S22.2 Fracture of sternum	0.000	0.992	0.008
S22.1 Multiple fractures of thoracic spine	0.000	0.992	0.008
W29.5 Trade and service area	0.007	0.993	0.000
H60.3 Other infective otitis externa	0.007	0.993	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.993	0.007
C15.5 Lower third of oesophagus	0.007	0.993	0.000
R25.1 Tremor, unspecified	0.007	0.993	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.993	0.007
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.993	0.006
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.993	0.006
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.993	0.006
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.993	0.006
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.993	0.007
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.994	0.006
T79.3 Post-traumatic wound infection, not elsewhere classified	0.006	0.994	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.994	0.006
C15.9 Oesophagus, unspecified	0.006	0.994	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.006	0.994	0.000
D60.8 Other acquired pure red cell aplasias	0.006	0.994	0.000
D60.1 Transient acquired pure red cell aplasia	0.006	0.994	0.000
D60.0 Chronic acquired pure red cell aplasia	0.006	0.994	0.000
W29.09 Contact with other powered hand tools and household machinery; Home; During unspecified activity	0.006	0.994	0.000
W29.62 Contact with other powered hand tools and household machinery; Industrial and construction area ;While working for income	0.006	0.994	0.000
W29.82 Contact with other powered hand tools and household machinery; Other specified places ;While working for income	0.006	0.994	0.000
T79.6 Traumatic ischaemia of muscle	0.006	0.994	0.000
C15 Malignant neoplasm of oesophagus	0.006	0.994	0.000
S22.21 Fracture of sternum (open)	0.000	0.994	0.006
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.994	0.006
M77.47 Metatarsalgia-Ankle/Foot	0.006	0.994	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.006	0.994	0.000
S22.4 Multiple fractures of ribs	0.000	0.994	0.005
T79 Certain early complications of trauma, not elsewhere classified	0.006	0.994	0.000
Z93 Artificial opening status	0.005	0.995	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.995	0.005
R25 Abnormal involuntary movements	0.005	0.995	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.995	0.005
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.995	0.005
K13.7 Other and unspecified lesions of oral mucosa	0.005	0.995	0.000
C15.3 Upper third of oesophagus	0.005	0.995	0.000
R25.2 Cramp and spasm	0.005	0.995	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.995	0.005
D61 Other aplastic anaemias	0.005	0.995	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.995	0.005
S40.0 Contusion of shoulder and upper arm	0.000	0.995	0.005
S22.20 Fracture of sternum (closed)	0.000	0.995	0.005
S82.10 Fracture of upper end of tibia (closed)	0.000	0.995	0.005
R25.8 Other and unspecified abnormal involuntary movements	0.005	0.995	0.000
K01.1 Impacted teeth	0.005	0.995	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.995	0.004
T79.5 Traumatic anuria	0.004	0.995	0.000
T79.4 Traumatic shock	0.004	0.995	0.000
C15.8 Overlapping lesion of oesophagus	0.004	0.995	0.000
C15.2 Abdominal part of oesophagus	0.004	0.995	0.000
C15.1 Thoracic part of oesophagus	0.004	0.995	0.000
C15.0 Cervical part of oesophagus	0.004	0.995	0.000
C15.4 Middle third of oesophagus	0.004	0.995	0.000
T79.8 Other early complications of trauma	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
S20-S29 Injuries to the thorax	0.000	0.996	0.004
D64 Other anaemias	0.004	0.996	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.004	0.996	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.996	0.004
V23.4 Driver injured in traffic accident	0.000	0.996	0.004
Z93.9 Artificial opening status, unspecified	0.004	0.996	0.000
T79.9 Unspecified early complication of trauma	0.004	0.996	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.004	0.996	0.000
T79.1 Fat embolism (traumatic)	0.004	0.996	0.000
T79.0 Air embolism (traumatic)	0.004	0.996	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
Z93.8 Other artificial opening status	0.004	0.996	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.004	0.996	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.004	0.996	0.000
R25.0 Abnormal head movements	0.004	0.996	0.000
R25.3 Fasciculation	0.004	0.996	0.000
S29 Other and unspecified injuries of thorax	0.000	0.996	0.004
D61.1 Drug-induced aplastic anaemia	0.004	0.996	0.000
K63.2 Fistula of intestine	0.004	0.996	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.996	0.004
D61.8 Other specified aplastic anaemias	0.003	0.996	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.996	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.996	0.000
S21 Open wound of thorax	0.000	0.996	0.004
H00 Hordeolum and chalazion	0.004	0.996	0.000
S29.9 Unspecified injury of thorax	0.000	0.996	0.003
H60-H62 Diseases of external ear	0.003	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.996	0.003
D50 Iron deficiency anaemia	0.003	0.996	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.997	0.003
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.997	0.003
S26 Injury of heart	0.000	0.997	0.003
S25 Injury of blood vessels of thorax	0.000	0.997	0.003
D64.4 Congenital dyserythropoietic anaemia	0.003	0.997	0.000
D64.3 Other sideroblastic anaemias	0.003	0.997	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.003	0.997	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.003	0.997	0.000
D64.0 Hereditary sideroblastic anaemia	0.003	0.997	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.997	0.003
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.997	0.003
S82.1 Fracture of upper end of tibia	0.000	0.997	0.003
S21.2 Open wound of back wall of thorax	0.000	0.997	0.003
S24 Injury of nerves and spinal cord at thorax level	0.000	0.997	0.003
S40 Superficial injury of shoulder and upper arm	0.000	0.997	0.003
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
Z93.6 Other artificial openings of urinary tract status	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.997	0.003
S29.8 Other specified injuries of thorax	0.000	0.997	0.003
S29.7 Multiple injuries of thorax	0.000	0.997	0.003
S29.0 Injury of muscle and tendon at thorax level	0.000	0.997	0.003
S21.9 Open wound of thorax, part unspecified	0.000	0.997	0.003
Z93.1 Gastrostomy status	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
D64.8 Other specified anaemias	0.003	0.997	0.000
T79.7 Traumatic subcutaneous emphysema	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.997	0.003
S82.11 Fracture of upper end of tibia (open)	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
S21.8 Open wound of other parts of thorax	0.000	0.997	0.003
S21.7 Multiple open wounds of thoracic wall	0.000	0.997	0.003
S21.0 Open wound of breast	0.000	0.997	0.003
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.997	0.003
N60.2 Fibroadenosis of breast	0.000	0.997	0.003
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
D50.1 Sideropenic dysphagia	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
M77.4 Metatarsalgia	0.003	0.997	0.000
M67.43 Ganglion, wrist	0.003	0.997	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.997	0.002
S25.8 Injury of other blood vessels of thorax	0.000	0.997	0.002
S25.7 Injury of multiple blood vessels of thorax	0.000	0.997	0.002
S25.5 Injury of intercostal blood vessels	0.000	0.997	0.002
S25.4 Injury of pulmonary blood vessels	0.000	0.997	0.002
S25.3 Injury of innominate or subclavian vein	0.000	0.997	0.002
S25.2 Injury of superior vena cava	0.000	0.997	0.002
S25.1 Injury of innominate or subclavian artery	0.000	0.997	0.002
S25.0 Injury of thoracic aorta	0.000	0.997	0.002
S26.9 Injury of heart, unspecified	0.000	0.997	0.002
S26.8 Other injuries of heart	0.000	0.997	0.002
S26.0 Injury of heart with haemopericardium	0.000	0.997	0.002
S28.1 Traumatic amputation of part of thorax	0.000	0.997	0.002
S28.0 Crushed chest	0.000	0.997	0.002
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.997	0.002
S23.3 Sprain and strain of thoracic spine	0.000	0.997	0.002
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.997	0.002
S23.1 Dislocation of thoracic vertebra	0.000	0.997	0.002
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.997	0.002
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.997	0.003
S24.6 Injury of unspecified nerve of thorax	0.000	0.997	0.002
S24.5 Injury of other nerves of thorax	0.000	0.997	0.002
S24.4 Injury of thoracic sympathetic nerves	0.000	0.997	0.002
S24.3 Injury of peripheral nerves of thorax	0.000	0.997	0.002
S24.2 Injury of nerve root of thoracic spine	0.000	0.997	0.002
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.997	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations