TreeWAS – Variant ID: rs10979182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M84 Disorders of continuity of bone	0.104	0.896	0.000
M80-M85 Disorders of bone density and structure	0.104	0.896	0.000
M85 Other disorders of bone density and structure	0.103	0.897	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.101	0.899	0.000
M81 Osteoporosis without pathological fracture	0.100	0.900	0.000
M85.8 Other specified disorders of bone density and structure	0.097	0.903	0.000
M85.0 Fibrous dysplasia (monostotic)	0.096	0.904	0.000
M81.4 Drug-induced osteoporosis	0.092	0.908	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.092	0.908	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.088	0.912	0.000
M81.0 Postmenopausal osteoporosis	0.087	0.912	0.000
M84.4 Pathological fracture, not elsewhere classified	0.087	0.913	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.085	0.915	0.000
M81.9 Osteoporosis, unspecified	0.084	0.916	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.084	0.916	0.000
M84.0 Malunion of fracture	0.084	0.916	0.000
M85.4 Solitary bone cyst	0.083	0.916	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.083	0.917	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.083	0.917	0.000
M84.8 Other disorders of continuity of bone	0.083	0.917	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.082	0.918	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.082	0.918	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.081	0.919	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.080	0.920	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.079	0.921	0.000
M85.2 Hyperostosis of skull	0.077	0.922	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.077	0.923	0.000
M85.9 Disorder of bone density and structure, unspecified	0.077	0.923	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.077	0.923	0.000
M84.9 Disorder of continuity of bone, unspecified	0.075	0.925	0.000
M84.3 Stress fracture, not elsewhere classified	0.075	0.925	0.000
M84.2 Delayed union of fracture	0.074	0.925	0.000
M81.8 Other osteoporosis	0.074	0.926	0.000
M81.1 Postoophorectomy osteoporosis	0.074	0.926	0.000
M85.5 Aneurysmal bone cyst	0.074	0.926	0.000
M85.3 Osteitis condensans	0.074	0.926	0.000
M85.1 Skeletal fluorosis	0.074	0.926	0.000
M83 Adult osteomalacia	0.073	0.927	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.072	0.928	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.072	0.928	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.072	0.928	0.000
M81.6 Localised osteoporosis [Lequesne]	0.072	0.928	0.000
M81.5 Idiopathic osteoporosis	0.072	0.928	0.000
M84.06 Malunion of fracture (Lower leg)	0.072	0.928	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.071	0.929	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.071	0.929	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.071	0.929	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.070	0.930	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.070	0.930	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.070	0.930	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.070	0.930	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.069	0.931	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.069	0.931	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.069	0.931	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.069	0.931	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.069	0.931	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.069	0.931	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.069	0.931	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.069	0.931	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.069	0.931	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.069	0.931	0.000
M81.98 Osteoporosis, unspecified (Other)	0.068	0.932	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.068	0.932	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.068	0.932	0.000
M43 Other deforming dorsopathies	0.067	0.933	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.067	0.933	0.000
M81.2 Osteoporosis of disuse	0.066	0.933	0.000
M82 Osteoporosis in diseases classified elsewhere	0.066	0.934	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.066	0.934	0.000
M81.48 Drug-induced osteoporosis (Other)	0.066	0.934	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.066	0.934	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.066	0.934	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.066	0.934	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.066	0.934	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.066	0.934	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.066	0.934	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.066	0.934	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.066	0.934	0.000
M84.02 Malunion of fracture (Upper arm)	0.065	0.935	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.065	0.935	0.000
M84.08 Malunion of fracture (Other)	0.065	0.935	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.065	0.935	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.065	0.935	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.065	0.935	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.065	0.935	0.000
M40-M43 Deforming dorsopathies	0.065	0.935	0.000
M43.1 Spondylolisthesis	0.064	0.936	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.063	0.937	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.063	0.937	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.063	0.937	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.063	0.937	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.063	0.937	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.063	0.937	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.063	0.937	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.063	0.937	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.063	0.937	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.063	0.937	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.062	0.938	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.062	0.938	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.062	0.938	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.062	0.938	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.062	0.938	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.062	0.938	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.062	0.938	0.000
M43.0 Spondylolysis	0.062	0.938	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.062	0.938	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.061	0.939	0.000
M84.03 Malunion of fracture (Forearm)	0.061	0.939	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.061	0.939	0.000
M84.09 Malunion of fracture (Site unspecified)	0.060	0.940	0.000
M84.00 Malunion of fracture (Multiple sites)	0.060	0.940	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.060	0.940	0.000
M85.48 Solitary bone cyst (Other)	0.060	0.940	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.060	0.940	0.000
M85.44 Solitary bone cyst (Hand)	0.060	0.940	0.000
M85.43 Solitary bone cyst (Forearm)	0.060	0.940	0.000
M85.42 Solitary bone cyst (Upper arm)	0.060	0.940	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.060	0.940	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.060	0.940	0.000
M85.20 Hyperostosis of skull-Mult sites	0.060	0.940	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.059	0.940	0.000
M84.88 Other disorders of continuity of bone (Other)	0.059	0.940	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.059	0.940	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.059	0.940	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.059	0.940	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.059	0.940	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.059	0.940	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.059	0.940	0.000
M45 Ankylosing spondylitis	0.059	0.941	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.059	0.941	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.059	0.941	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.059	0.941	0.000
M45-M49 Spondylopathies	0.059	0.941	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.059	0.941	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.058	0.942	0.000
M85.46 Solitary bone cyst (Lower leg)	0.058	0.942	0.000
M43.6 Torticollis	0.056	0.944	0.000
M85.29 Hyperostosis of skull-Site unspec	0.056	0.944	0.000
M85.28 Hyperostosis of skull-Other	0.056	0.944	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.056	0.944	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.056	0.944	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.056	0.944	0.000
M85.24 Hyperostosis of skull-Hand	0.056	0.944	0.000
M85.23 Hyperostosis of skull-Forearm	0.056	0.944	0.000
M85.21 Hyperostosis of skull-Shldr region	0.056	0.944	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.055	0.944	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.055	0.944	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.055	0.944	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.055	0.944	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.055	0.944	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.055	0.944	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.055	0.944	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.055	0.944	0.000
M85.22 Hyperostosis of skull-Upper arm	0.055	0.944	0.000
M81.80 Other osteoporosis (Multiple sites)	0.055	0.944	0.000
M83.1 Senile osteomalacia	0.055	0.945	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.055	0.945	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.055	0.945	0.000
M48 Other spondylopathies	0.055	0.945	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.055	0.945	0.000
M40 Kyphosis and lordosis	0.054	0.946	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.054	0.946	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.054	0.946	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.054	0.946	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.054	0.946	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.054	0.946	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.054	0.946	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.054	0.946	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.054	0.946	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.054	0.946	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.054	0.946	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.054	0.946	0.000
M41 Scoliosis	0.054	0.946	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.054	0.946	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.054	0.946	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.054	0.946	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.054	0.946	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.054	0.946	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.054	0.946	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.054	0.946	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.054	0.946	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.054	0.946	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.054	0.946	0.000
M84.28 Delayed union of fracture (Other)	0.054	0.946	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.054	0.946	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.054	0.946	0.000
M84.24 Delayed union of fracture (Hand)	0.054	0.946	0.000
M84.23 Delayed union of fracture (Forearm)	0.054	0.946	0.000
M84.22 Delayed union of fracture (Upper arm)	0.054	0.946	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.054	0.946	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.054	0.946	0.000
M81.89 Other osteoporosis (Site unspecified)	0.053	0.946	0.000
M81.88 Other osteoporosis (Other)	0.053	0.946	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.053	0.946	0.000
M81.86 Other osteoporosis (Lower leg)	0.053	0.946	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.053	0.946	0.000
M81.84 Other osteoporosis (Hand)	0.053	0.946	0.000
M81.83 Other osteoporosis (Forearm)	0.053	0.946	0.000
M81.82 Other osteoporosis (Upper arm)	0.053	0.946	0.000
M81.81 Other osteoporosis (Shoulder region)	0.053	0.946	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.053	0.947	0.000
M84.26 Delayed union of fracture (Lower leg)	0.053	0.947	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.053	0.947	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.053	0.947	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.053	0.947	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.053	0.947	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.053	0.947	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.053	0.947	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.053	0.947	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.053	0.947	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.053	0.947	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.053	0.947	0.000
M85.18 Skeletal fluorosis (Other)	0.053	0.947	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.053	0.947	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.053	0.947	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.053	0.947	0.000
M85.14 Skeletal fluorosis (Hand)	0.053	0.947	0.000
M85.13 Skeletal fluorosis (Forearm)	0.053	0.947	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.053	0.947	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.053	0.947	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.053	0.947	0.000
M85.39 Osteitis condensans (Site unspecified)	0.053	0.947	0.000
M85.38 Osteitis condensans (Other)	0.053	0.947	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.053	0.947	0.000
M85.36 Osteitis condensans (Lower leg)	0.053	0.947	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.053	0.947	0.000
M85.34 Osteitis condensans (Hand)	0.053	0.947	0.000
M85.33 Osteitis condensans (Forearm)	0.053	0.947	0.000
M85.32 Osteitis condensans (Upper arm)	0.053	0.947	0.000
M85.31 Osteitis condensans (Shoulder region)	0.053	0.947	0.000
M85.30 Osteitis condensans (Multiple sites)	0.053	0.947	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.053	0.947	0.000
M85.58 Aneurysmal bone cyst (Other)	0.053	0.947	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.053	0.947	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.053	0.947	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.053	0.947	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.053	0.947	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.053	0.947	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.053	0.947	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.053	0.947	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.053	0.947	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.053	0.947	0.000
M43.09 Spondylolysis (Site unspecified)	0.053	0.947	0.000
M83.9 Adult osteomalacia, unspecified	0.052	0.947	0.000
M83.5 Other drug-induced osteomalacia in adults	0.052	0.947	0.000
M83.4 Aluminum bone disease	0.052	0.947	0.000
M83.2 Adult osteomalacia due to malabsorption	0.052	0.947	0.000
M83.0 Puerperal osteomalacia	0.052	0.947	0.000
M83.3 Adult osteomalacia due to malnutrition	0.052	0.947	0.000
M43.2 Other fusion of spine	0.052	0.948	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.052	0.948	0.000
M81.58 Idiopathic osteoporosis (Other)	0.052	0.948	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.052	0.948	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.052	0.948	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.052	0.948	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.052	0.948	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.052	0.948	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.052	0.948	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.052	0.948	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.052	0.948	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.052	0.948	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.052	0.948	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.052	0.948	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.052	0.948	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.052	0.948	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.052	0.948	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.052	0.948	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.052	0.948	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.052	0.948	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.052	0.948	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.051	0.948	0.000
M43.02 Spondylolysis (Cervical region)	0.051	0.949	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.051	0.949	0.000
M84.01 Malunion of fracture (Shoulder region)	0.051	0.949	0.000
M46 Other inflammatory spondylopathies	0.050	0.950	0.000
M43.06 Spondylolysis (Lumbar region)	0.049	0.951	0.000
M84.04 Malunion of fracture (Hand)	0.049	0.951	0.000
M48.0 Spinal stenosis	0.049	0.951	0.000
M43.5 Other recurrent vertebral subluxation	0.048	0.952	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.048	0.952	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.048	0.952	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.048	0.952	0.000
M60-M63 Disorders of muscles	0.048	0.952	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.048	0.952	0.000
M81.28 Osteoporosis of disuse (Other)	0.048	0.952	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.048	0.952	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.048	0.952	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.048	0.952	0.000
M81.24 Osteoporosis of disuse (Hand)	0.048	0.952	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.048	0.952	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.048	0.952	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.048	0.952	0.000
M43.62 Torticollis-Cervical	0.048	0.952	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.048	0.952	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.048	0.952	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.048	0.952	0.000
M83.8 Other adult osteomalacia	0.048	0.952	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.047	0.952	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.047	0.952	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.047	0.952	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.047	0.952	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.047	0.952	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.047	0.952	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.047	0.952	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.047	0.952	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.047	0.952	0.000
M43.9 Deforming dorsopathy, unspecified	0.047	0.953	0.000
M43.8 Other specified deforming dorsopathies	0.047	0.953	0.000
M42 Spinal osteochondrosis	0.047	0.953	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.047	0.953	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.046	0.954	0.000
M40.2 Other and unspecified kyphosis	0.046	0.954	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.046	0.954	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.046	0.954	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.046	0.954	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.046	0.954	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.045	0.955	0.000
M99 Biomechanical lesions, not elsewhere classified	0.045	0.955	0.000
M48.8 Other specified spondylopathies	0.045	0.955	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.044	0.955	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.044	0.955	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.044	0.955	0.000
M43.04 Spondylolysis (Thoracic region)	0.044	0.955	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.044	0.955	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.044	0.955	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.044	0.955	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.044	0.956	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.044	0.956	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.044	0.956	0.000
M41.9 Scoliosis, unspecified	0.044	0.956	0.000
N80.1 Endometriosis of ovary	0.000	0.957	0.043
M48.04 Spinal stenosis (Thoracic region)	0.043	0.957	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.043	0.957	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.043	0.957	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.043	0.957	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.043	0.957	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.043	0.957	0.000
M41.5 Other secondary scoliosis	0.043	0.957	0.000
M00-M03 Infectious arthropathies	0.043	0.957	0.000
M83.12 Senile osteomalacia (Upper arm)	0.042	0.957	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.042	0.957	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.042	0.958	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.042	0.958	0.000
M43.29 Other fusion of spine (Site unspecified)	0.042	0.958	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.042	0.958	0.000
M48.9 Spondylopathy, unspecified	0.041	0.959	0.000
N80 Endometriosis	0.000	0.959	0.041
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.041	0.959	0.000
M62 Other disorders of muscle	0.041	0.959	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.041	0.959	0.000
M41.4 Neuromuscular scoliosis	0.041	0.959	0.000
N80.2 Endometriosis of Fallopian tube	0.000	0.959	0.041
M48.06 Spinal stenosis (Lumbar region)	0.041	0.959	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.041	0.959	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.041	0.959	0.000
M40.5 Lordosis, unspecified	0.040	0.959	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.041	0.959	0.000
M43.69 Torticollis-Site unspe	0.040	0.960	0.000
M43.68 Torticollis-Sacral/sacrococ	0.040	0.960	0.000
M43.67 Torticollis-Lumbosacral	0.040	0.960	0.000
M43.66 Torticollis-Lumbar	0.040	0.960	0.000
M43.65 Torticollis-Thoracolumbar	0.040	0.960	0.000
M43.64 Torticollis-Thoracic	0.040	0.960	0.000
M43.63 Torticollis-Cervicothoracic	0.040	0.960	0.000
M43.61 Torticollis-Occipit-atl-axl	0.040	0.960	0.000
M43.60 Torticollis-Mult site	0.040	0.960	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.040	0.960	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.040	0.960	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.040	0.960	0.000
M83.18 Senile osteomalacia (Other)	0.040	0.960	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.040	0.960	0.000
M83.16 Senile osteomalacia (Lower leg)	0.040	0.960	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.040	0.960	0.000
M83.14 Senile osteomalacia (Hand)	0.040	0.960	0.000
M83.13 Senile osteomalacia (Forearm)	0.040	0.960	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.040	0.960	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.040	0.960	0.000
M96.5 Postradiation scoliosis	0.040	0.960	0.000
M82.1 Osteoporosis in endocrine disorders	0.040	0.960	0.000
N80.9 Endometriosis, unspecified	0.000	0.960	0.040
M48.4 Fatigue fracture of vertebra	0.039	0.961	0.000
M48.3 Traumatic spondylopathy	0.039	0.961	0.000
M48.2 Kissing spine	0.039	0.961	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.039	0.961	0.000
M40.4 Other lordosis	0.039	0.961	0.000
M40.3 Flatback syndrome	0.039	0.961	0.000
M40.1 Other secondary kyphosis	0.039	0.961	0.000
M40.0 Postural kyphosis	0.039	0.961	0.000
M46.4 Discitis, unspecified	0.039	0.961	0.000
M49 Spondylopathies in diseases classified elsewhere	0.039	0.961	0.000
M41.3 Thoracogenic scoliosis	0.039	0.961	0.000
M41.2 Other idiopathic scoliosis	0.039	0.961	0.000
M41.1 Juvenile idiopathic scoliosis	0.039	0.961	0.000
M41.0 Infantile idiopathic scoliosis	0.039	0.961	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.039	0.961	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.038	0.962	0.000
M96.4 Postsurgical lordosis	0.038	0.962	0.000
M96.3 Postlaminectomy kyphosis	0.038	0.962	0.000
M96.2 Postradiation kyphosis	0.038	0.962	0.000
M85.6 Other cyst of bone	0.038	0.962	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.962	0.038
M46.1 Sacro-iliitis, not elsewhere classified	0.038	0.962	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.038	0.962	0.000
M83.08 Puerperal osteomalacia (Other)	0.038	0.962	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.038	0.962	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.038	0.962	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.038	0.962	0.000
M83.04 Puerperal osteomalacia (Hand)	0.038	0.962	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.038	0.962	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.038	0.962	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.038	0.962	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.038	0.962	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.038	0.962	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.038	0.962	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.038	0.962	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.038	0.962	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.038	0.962	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.038	0.962	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.038	0.962	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.038	0.962	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.038	0.962	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.038	0.962	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.038	0.962	0.000
M83.48 Aluminium bone disease (Other)	0.038	0.962	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.038	0.962	0.000
M83.46 Aluminium bone disease (Lower leg)	0.038	0.962	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.038	0.962	0.000
M83.44 Aluminium bone disease (Hand)	0.038	0.962	0.000
M83.43 Aluminium bone disease (Forearm)	0.038	0.962	0.000
M83.42 Aluminium bone disease (Upper arm)	0.038	0.962	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.038	0.962	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.038	0.962	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.038	0.962	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.038	0.962	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.038	0.962	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.038	0.962	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.038	0.962	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.038	0.962	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.038	0.962	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.038	0.962	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.038	0.962	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.038	0.962	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.038	0.962	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.038	0.962	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.038	0.962	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.038	0.962	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.038	0.962	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.038	0.962	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.038	0.962	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.038	0.962	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.038	0.962	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.038	0.962	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.038	0.962	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.038	0.962	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.038	0.962	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.038	0.962	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.038	0.962	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.038	0.962	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.038	0.962	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.038	0.962	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.038	0.962	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.038	0.962	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.038	0.962	0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.038	0.962	0.000
M43.27 Other fusion of spine (Lumbosacral region)	0.038	0.962	0.000
M43.26 Other fusion of spine (Lumbar region)	0.038	0.962	0.000
M43.25 Other fusion of spine (Thoracolumbar region)	0.038	0.962	0.000
M43.24 Other fusion of spine (Thoracic region)	0.038	0.962	0.000
M43.23 Other fusion of spine (Cervicothoracic region)	0.038	0.962	0.000
M43.22 Other fusion of spine (Cervical region)	0.038	0.962	0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.038	0.962	0.000
M43.20 Other fusion of spine (Multiple sites in spine)	0.038	0.962	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.037	0.963	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.036	0.963	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.036	0.963	0.000
M99.8 Other biomechanical lesions	0.036	0.964	0.000
M80 Osteoporosis with pathological fracture	0.036	0.964	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.036	0.964	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.036	0.964	0.000
M41.8 Other forms of scoliosis	0.036	0.964	0.000
M46.8 Other specified inflammatory spondylopathies	0.036	0.964	0.000
M46.5 Other infective spondylopathies	0.036	0.964	0.000
M46.2 Osteomyelitis of vertebra	0.035	0.965	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.035	0.965	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.035	0.965	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.035	0.965	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.035	0.965	0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.035	0.965	0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.035	0.965	0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.035	0.965	0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.035	0.965	0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.035	0.965	0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.035	0.965	0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.035	0.965	0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.035	0.965	0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.035	0.965	0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.035	0.965	0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.035	0.965	0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.035	0.965	0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.035	0.965	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations