TreeWAS – Variant ID: rs10983554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.999	0.001	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.999	0.001	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.999	0.001	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.999	0.001	0.000
R41.0 Disorientation, unspecified	0.998	0.002	0.000
I73.9 Peripheral vascular disease, unspecified	0.998	0.002	0.000
I73 Other peripheral vascular diseases	0.998	0.002	0.000
R94 Abnormal results of function studies	0.997	0.003	0.000
R94.5 Abnormal results of liver function studies	0.997	0.003	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.989	0.011	0.000
Chapter XX External causes of morbidity and mortality	0.986	0.014	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.979	0.021	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.978	0.022	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.976	0.024	0.000
Chapter VIII Diseases of the ear and mastoid process	0.976	0.024	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.975	0.025	0.000
Chapter XI Diseases of the digestive system	0.973	0.027	0.000
Chapter X Diseases of the respiratory system	0.973	0.027	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.972	0.028	0.000
J90-J94 Other diseases of pleura	0.969	0.031	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.969	0.031	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.967	0.033	0.000
K81 Cholecystitis	0.963	0.037	0.000
K83 Other diseases of biliary tract	0.962	0.038	0.000
K81.1 Chronic cholecystitis	0.959	0.041	0.000
J92 Pleural plaque	0.956	0.044	0.000
I22 Subsequent myocardial infarction	0.950	0.050	0.000
J92.0 Pleural plaque with presence of asbestos	0.949	0.051	0.000
K82 Other diseases of gallbladder	0.945	0.055	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.944	0.056	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.927	0.073	0.000
I25.3 Aneurysm of heart	0.926	0.074	0.000
R44.1 Visual hallucinations	0.922	0.078	0.000
H60-H62 Diseases of external ear	0.917	0.083	0.000
R45 Symptoms and signs involving emotional state	0.917	0.083	0.000
S60-S69 Injuries to the wrist and hand	0.916	0.084	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.913	0.087	0.000
I27 Other pulmonary heart diseases	0.912	0.088	0.000
I30-I52 Other forms of heart disease	0.906	0.094	0.000
J84 Other interstitial pulmonary diseases	0.905	0.095	0.000
K82.4 Cholesterolosis of gallbladder	0.904	0.096	0.000
K70-K77 Diseases of liver	0.903	0.097	0.000
T82.1 Mechanical complication of cardiac electronic device	0.903	0.097	0.000
W20-W49 Exposure to inanimate mechanical forces	0.902	0.097	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.899	0.101	0.000
K83.0 Cholangitis	0.899	0.101	0.000
T82.3 Mechanical complication of other vascular grafts	0.898	0.102	0.000
K82.8 Other specified diseases of gallbladder	0.893	0.107	0.000
R25 Abnormal involuntary movements	0.892	0.108	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.891	0.109	0.000
I25.2 Old myocardial infarction	0.889	0.111	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.889	0.111	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.887	0.113	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.886	0.114	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.884	0.116	0.000
K83.8 Other specified diseases of biliary tract	0.884	0.116	0.000
H61 Other disorders of external ear	0.883	0.117	0.000
H65-H75 Diseases of middle ear and mastoid	0.883	0.117	0.000
J90 Pleural effusion, not elsewhere classified	0.883	0.117	0.000
Y57 Other and unspecified drugs and medicaments	0.882	0.118	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.876	0.124	0.000
I70 Atherosclerosis	0.873	0.127	0.000
I27.2 Other secondary pulmonary hypertension	0.870	0.130	0.000
I25.5 Ischaemic cardiomyopathy	0.865	0.135	0.000
T18 Foreign body in alimentary tract	0.862	0.138	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.859	0.141	0.000
I25.1 Atherosclerotic heart disease	0.856	0.144	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.855	0.145	0.000
R44.0 Auditory hallucinations	0.852	0.148	0.000
Chapter V Mental and behavioural disorders	0.849	0.151	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.848	0.152	0.000
I26 Pulmonary embolism	0.846	0.154	0.000
I31 Other diseases of pericardium	0.838	0.162	0.000
K74 Fibrosis and cirrhosis of liver	0.836	0.164	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.836	0.164	0.000
W22 Striking against or struck by other objects	0.832	0.168	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.830	0.170	0.000
I72 Other aneurysm	0.828	0.172	0.000
T18.1 Foreign body in oesophagus	0.825	0.175	0.000
R25.1 Tremor, unspecified	0.823	0.177	0.000
H72 Perforation of tympanic membrane	0.822	0.178	0.000
K70 Alcoholic liver disease	0.822	0.178	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.819	0.181	0.000
I77 Other disorders of arteries and arterioles	0.816	0.184	0.000
K83.1 Obstruction of bile duct	0.814	0.186	0.000
I31.3 Pericardial effusion (noninflammatory)	0.810	0.190	0.000
F41 Other anxiety disorders	0.807	0.193	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.803	0.197	0.000
I45 Other conduction disorders	0.802	0.198	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.801	0.199	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.801	0.199	0.000
Y00-Y09 Assault	0.799	0.201	0.000
Y52 Agents primarily affecting the cardiovascular system	0.798	0.202	0.000
I51 Complications and ill-defined descriptions of heart disease	0.797	0.203	0.000
I22.8 Subsequent myocardial infarction of other sites	0.795	0.205	0.000
S67 Crushing injury of wrist and hand	0.795	0.205	0.000
I73.8 Other specified peripheral vascular diseases	0.794	0.206	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.793	0.207	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.792	0.208	0.000
T63 Toxic effect of contact with venomous animals	0.791	0.208	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.791	0.209	0.000
I30 Acute pericarditis	0.787	0.213	0.000
I42 Cardiomyopathy	0.786	0.214	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.786	0.214	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.785	0.215	0.000
H61.2 Impacted cerumen	0.785	0.215	0.000
K74.6 Other and unspecified cirrhosis of liver	0.783	0.217	0.000
R44.3 Hallucinations, unspecified	0.781	0.219	0.000
V70-V79 Bus occupant injured in transport accident	0.781	0.219	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.779	0.221	0.000
J81 Pulmonary oedema	0.778	0.222	0.000
K40-K46 Hernia	0.777	0.223	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.774	0.226	0.000
R45.1 Restlessness and agitation	0.773	0.227	0.000
K81.0 Acute cholecystitis	0.772	0.228	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.769	0.231	0.000
H74 Other disorders of middle ear and mastoid	0.767	0.233	0.000
T23 Burn and corrosion of wrist and hand	0.766	0.234	0.000
K70.9 Alcoholic liver disease, unspecified	0.764	0.236	0.000
S50-S59 Injuries to the elbow and forearm	0.764	0.236	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.764	0.236	0.000
I60-I69 Cerebrovascular diseases	0.764	0.236	0.000
R41.2 Retrograde amnesia	0.763	0.237	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.763	0.237	0.000
I50 Heart failure	0.763	0.237	0.000
H61.0 Perichondritis of external ear	0.763	0.237	0.000
R45.8 Other symptoms and signs involving emotional state	0.761	0.239	0.000
J93 Pneumothorax	0.760	0.240	0.000
H80-H83 Diseases of inner ear	0.759	0.241	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.757	0.243	0.000
S90-S99 Injuries to the ankle and foot	0.757	0.243	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.755	0.245	0.000
W50-W64 Exposure to animate mechanical forces	0.754	0.246	0.000
W75-W84 Other accidental threats to breathing	0.753	0.246	0.000
R41.3 Other amnesia	0.752	0.248	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.751	0.249	0.000
J95-J99 Other diseases of the respiratory system	0.750	0.250	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.750	0.250	0.000
I25.4 Coronary artery aneurysm	0.749	0.251	0.000
T00-T07 Injuries involving multiple body regions	0.749	0.251	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.748	0.252	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.748	0.252	0.000
J94 Other pleural conditions	0.748	0.252	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.748	0.252	0.000
Y57.6 Other diagnostic agents	0.746	0.254	0.000
J60-J70 Lung diseases due to external agents	0.746	0.254	0.000
R82 Other abnormal findings in urine	0.742	0.258	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.740	0.260	0.000
V10-V19 Pedal cyclist injured in transport accident	0.738	0.262	0.000
F40 Phobic anxiety disorders	0.737	0.263	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.737	0.263	0.000
Y57.9 Drug or medicament, unspecified	0.736	0.264	0.000
X20-X29 Contact with venomous animals and plants	0.736	0.264	0.000
Y40 Systemic antibiotics	0.734	0.266	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.733	0.267	0.000
K50-K52 Noninfective enteritis and colitis	0.733	0.267	0.000
I28 Other diseases of pulmonary vessels	0.732	0.268	0.000
R45.6 Physical violence	0.731	0.269	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.731	0.269	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.730	0.270	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.730	0.270	0.000
Y48 Anaesthetics and therapeutic gases	0.729	0.271	0.000
X10-X19 Contact with heat and hot substances	0.729	0.271	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.728	0.272	0.000
S69 Other and unspecified injuries of wrist and hand	0.728	0.272	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.727	0.273	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.727	0.273	0.000
W45 Foreign body or object entering through skin	0.727	0.273	0.000
T88.4 Failed or difficult intubation	0.726	0.274	0.000
J80 Adult respiratory distress syndrome	0.726	0.274	0.000
V98-V99 Other and unspecified transport accidents	0.725	0.274	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.725	0.275	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.725	0.275	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.724	0.276	0.000
Y43 Primarily systemic agents	0.724	0.276	0.000
I45.6 Preexcitation syndrome	0.722	0.278	0.000
R40 Somnolence, stupor and coma	0.720	0.278	0.002
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.721	0.279	0.000
T58 Toxic effect of carbon monoxide	0.721	0.279	0.000
X50-X57 Overexertion, travel and privation	0.720	0.280	0.000
T21 Burn and corrosion of trunk	0.719	0.281	0.000
V01-V09 Pedestrian injured in transport accident	0.717	0.282	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
R41.1 Anterograde amnesia	0.717	0.283	0.000
K46 Unspecified abdominal hernia	0.717	0.283	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.716	0.284	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.716	0.284	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.715	0.285	0.000
R94.7 Abnormal results of other endocrine function studies	0.715	0.285	0.000
R94.6 Abnormal results of thyroid function studies	0.715	0.285	0.000
R94.2 Abnormal results of pulmonary function studies	0.715	0.285	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.715	0.285	0.000
R94.0 Abnormal results of function studies of central nervous system	0.715	0.285	0.000
T63.4 Venom of other arthropods	0.714	0.286	0.000
W22.9 Unspecified place	0.714	0.286	0.000
S68 Traumatic amputation of wrist and hand	0.714	0.286	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.713	0.287	0.000
H61.1 Non-infective disorders of pinna	0.711	0.289	0.000
K83.9 Disease of biliary tract, unspecified	0.711	0.289	0.000
I30.9 Acute pericarditis, unspecified	0.710	0.290	0.000
T33-T35 Frostbite	0.709	0.291	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.709	0.291	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.709	0.291	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.708	0.292	0.000
T51 Toxic effect of alcohol	0.708	0.292	0.000
I65.2 Occlusion and stenosis of carotid artery	0.708	0.292	0.000
R43 Disturbances of smell and taste	0.708	0.292	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.707	0.293	0.000
Y35-Y36 Legal intervention and operations of war	0.707	0.293	0.000
Y10-Y34 Event of undetermined intent	0.707	0.293	0.000
X85-X99 Assault	0.707	0.293	0.000
X30-X39 Exposure to forces of nature	0.707	0.293	0.000
X00-X09 Exposure to smoke, fire and flames	0.707	0.293	0.000
W65-W74 Accidental drowning and submersion	0.707	0.293	0.000
V95-V97 Air and space transport accidents	0.707	0.293	0.000
V90-V94 Water transport accidents	0.707	0.293	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.706	0.294	0.000
V20-V29 Motorcycle rider injured in transport accident	0.705	0.294	0.000
F41.1 Generalised anxiety disorder	0.704	0.296	0.000
K70.0 Alcoholic fatty liver	0.702	0.298	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.702	0.298	0.000
R44.2 Other hallucinations	0.702	0.298	0.000
F41.9 Anxiety disorder, unspecified	0.701	0.299	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.701	0.299	0.000
I27.8 Other specified pulmonary heart diseases	0.700	0.300	0.000
H61.9 Disorder of external ear, unspecified	0.700	0.300	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.699	0.301	0.000
K82.3 Fistula of gallbladder	0.699	0.301	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.697	0.303	0.000
I45.8 Other specified conduction disorders	0.696	0.304	0.000
Y57.8 Other drugs and medicaments	0.695	0.305	0.000
T88.5 Other complications of anaesthesia	0.694	0.306	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.693	0.307	0.000
Y59 Other and unspecified vaccines and biological substances	0.693	0.307	0.000
Y58 Bacterial vaccines	0.693	0.307	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.693	0.307	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.693	0.307	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.693	0.307	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.693	0.307	0.000
K90-K93 Other diseases of the digestive system	0.693	0.307	0.000
H72.0 Central perforation of tympanic membrane	0.692	0.308	0.000
R27 Other lack of coordination	0.692	0.308	0.000
H69 Other disorders of Eustachian tube	0.691	0.309	0.000
I67 Other cerebrovascular diseases	0.691	0.309	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.691	0.309	0.000
K81.8 Other cholecystitis	0.691	0.309	0.000
K83.5 Biliary cyst	0.690	0.310	0.000
K83.4 Spasm of sphincter of Oddi	0.690	0.310	0.000
K83.3 Fistula of bile duct	0.690	0.310	0.000
K83.2 Perforation of bile duct	0.690	0.310	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.689	0.311	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.689	0.311	0.000
K70.3 Alcoholic cirrhosis of liver	0.688	0.312	0.000
W20 Struck by thrown, projected or falling object	0.685	0.315	0.000
W21 Striking against or struck by sports equipment	0.685	0.315	0.000
H72.1 Attic perforation of tympanic membrane	0.684	0.315	0.000
W22.3 Sports and athletics area	0.683	0.317	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.682	0.318	0.000
I78 Diseases of capillaries	0.681	0.319	0.000
I36 Nonrheumatic tricuspid valve disorders	0.679	0.321	0.000
R29.6 Tendency to fall, not elsewhere classified	0.679	0.321	0.000
F41.2 Mixed anxiety and depressive disorder	0.679	0.321	0.000
I51.0 Cardiac septal defect, acquired	0.678	0.322	0.000
I42.9 Cardiomyopathy, unspecified	0.678	0.322	0.000
K82.0 Obstruction of gallbladder	0.677	0.322	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.676	0.324	0.000
V40-V49 Car occupant injured in transport accident	0.676	0.324	0.000
W22.2 School, other institution and public administrative area	0.676	0.324	0.000
I33 Acute and subacute endocarditis	0.674	0.326	0.000
I45.1 Other and unspecified right bundle-branch block	0.674	0.326	0.000
K75 Other inflammatory liver diseases	0.674	0.326	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.674	0.326	0.000
S80-S89 Injuries to the knee and lower leg	0.673	0.327	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.672	0.328	0.000
K45 Other abdominal hernia	0.672	0.328	0.000
R46 Symptoms and signs involving appearance and behaviour	0.671	0.329	0.000
I51.4 Myocarditis, unspecified	0.670	0.330	0.000
I72.4 Aneurysm of artery of lower extremity	0.670	0.330	0.000
J91 Pleural effusion in conditions classified elsewhere	0.669	0.330	0.000
S40-S49 Injuries to the shoulder and upper arm	0.669	0.331	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.669	0.331	0.000
I72.9 Aneurysm of unspecified site	0.668	0.332	0.000
I50.1 Left ventricular failure	0.668	0.332	0.000
R45.0 Nervousness	0.668	0.332	0.000
K50 Crohn's disease [regional enteritis]	0.668	0.332	0.000
H70 Mastoiditis and related conditions	0.667	0.332	0.000
S56 Injury of muscle and tendon at forearm level	0.667	0.333	0.000
I51.9 Heart disease, unspecified	0.667	0.333	0.000
W29 Contact with other powered hand tools and household machinery	0.667	0.333	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.667	0.333	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.666	0.334	0.000
H90-H95 Other disorders of ear	0.666	0.334	0.000
R77 Other abnormalities of plasma proteins	0.666	0.334	0.000
Y04 Assault by bodily force	0.666	0.334	0.000
S65 Injury of blood vessels at wrist and hand level	0.665	0.335	0.000
K73 Chronic hepatitis, not elsewhere classified	0.665	0.335	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.665	0.335	0.000
H61.3 Acquired stenosis of external ear canal	0.662	0.338	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.660	0.340	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.660	0.340	0.000
T79-T79 Certain early complications of trauma	0.659	0.341	0.000
T56 Toxic effect of metals	0.658	0.342	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.658	0.342	0.000
R45.7 State of emotional shock and stress, unspecified	0.657	0.342	0.000
R45.5 Hostility	0.657	0.342	0.000
R45.4 Irritability and anger	0.657	0.342	0.000
R45.3 Demoralisation and apathy	0.657	0.342	0.000
R45.2 Unhappiness	0.657	0.342	0.000
F00 Dementia in Alzheimer's disease	0.657	0.343	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.657	0.343	0.000
R40.0 Somnolence	0.656	0.344	0.000
T19 Foreign body in genito-urinary tract	0.655	0.345	0.000
T15 Foreign body on external eye	0.655	0.345	0.000
T16 Foreign body in ear	0.655	0.345	0.000
I27.1 Kyphoscoliotic heart disease	0.654	0.346	0.000
Y44 Agents primarily affecting blood constituents	0.653	0.347	0.000
Y46.2 Hydantoin derivatives	0.651	0.349	0.000
J93.9 Pneumothorax, unspecified	0.651	0.349	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.650	0.349	0.000
I72.3 Aneurysm of iliac artery	0.650	0.350	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.650	0.350	0.000
I52 Other heart disorders in diseases classified elsewhere	0.649	0.350	0.000
I48 Atrial fibrillation and flutter	0.649	0.350	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.649	0.350	0.000
I41 Myocarditis in diseases classified elsewhere	0.649	0.350	0.000
I40 Acute myocarditis	0.649	0.350	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.649	0.350	0.000
I32 Pericarditis in diseases classified elsewhere	0.649	0.350	0.000
J84.8 Other specified interstitial pulmonary diseases	0.649	0.351	0.000
J84.0 Alveolar and parietoalveolar conditions	0.649	0.351	0.000
I37 Pulmonary valve disorders	0.649	0.351	0.000
K77 Liver disorders in diseases classified elsewhere	0.648	0.352	0.000
K71 Toxic liver disease	0.648	0.352	0.000
W46 Contact with hypodermic needle	0.647	0.353	0.000
W43 Exposure to vibration	0.647	0.353	0.000
W42 Exposure to noise	0.647	0.353	0.000
W41 Exposure to high-pressure jet	0.647	0.353	0.000
W40 Explosion of other materials	0.647	0.353	0.000
W39 Discharge of firework	0.647	0.353	0.000
W38 Explosion and rupture of other specified pressurised devices	0.647	0.353	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.647	0.353	0.000
W36 Explosion and rupture of gas cylinder	0.647	0.353	0.000
W35 Explosion and rupture of boiler	0.647	0.353	0.000
W34 Discharge from other and unspecified firearms	0.647	0.353	0.000
W33 Rifle, shotgun and larger firearm discharge	0.647	0.353	0.000
W32 Handgun discharge	0.647	0.353	0.000
W31 Contact with other and unspecified machinery	0.647	0.353	0.000
W30 Contact with agricultural machinery	0.647	0.353	0.000
W28 Contact with powered lawn mower	0.647	0.353	0.000
W27 Contact with nonpowered hand tool	0.647	0.353	0.000
W26 Contact with knife, sword or dagger	0.647	0.353	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.647	0.353	0.000
T65 Toxic effect of other and unspecified substances	0.645	0.355	0.000
T62 Toxic effect of other noxious substances eaten as food	0.645	0.355	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.645	0.355	0.000
T60 Toxic effect of pesticides	0.645	0.355	0.000
T57 Toxic effect of other inorganic substances	0.645	0.355	0.000
T54 Toxic effect of corrosive substances	0.645	0.355	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.645	0.355	0.000
T52 Toxic effect of organic solvents	0.645	0.355	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.645	0.355	0.000
T55 Toxic effect of soaps and detergents	0.645	0.355	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.645	0.355	0.000
K92 Other diseases of digestive system	0.644	0.356	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.643	0.357	0.000
H83 Other diseases of inner ear	0.643	0.357	0.000
F43 Reaction to severe stress, and adjustment disorders	0.642	0.358	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.640	0.360	0.000
K74.0 Hepatic fibrosis	0.640	0.360	0.000
R25.0 Abnormal head movements	0.640	0.360	0.000
T17 Foreign body in respiratory tract	0.640	0.360	0.000
T25 Burn and corrosion of ankle and foot	0.639	0.361	0.000
F45 Somatoform disorders	0.638	0.362	0.000
H71 Cholesteatoma of middle ear	0.637	0.363	0.000
I27.0 Primary pulmonary hypertension	0.637	0.363	0.000
I77.1 Stricture of artery	0.637	0.363	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.635	0.365	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.635	0.365	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.635	0.365	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.635	0.365	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.635	0.365	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.635	0.365	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.635	0.365	0.000
Y51.0 Anticholinesterase agents	0.635	0.365	0.000
V78 Bus occupant injured in noncollision transport accident	0.634	0.366	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.633	0.367	0.000
H68 Eustachian salpingitis and obstruction	0.633	0.367	0.000
H67 Otitis media in diseases classified elsewhere	0.633	0.367	0.000
Y57.7 Vitamins, not elsewhere classified	0.633	0.367	0.000
Y57.4 Pharmaceutical excipients	0.633	0.367	0.000
Y57.3 Alcohol deterrents	0.633	0.367	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.633	0.367	0.000
Y57.1 Lipotropic drugs	0.633	0.367	0.000
Y57.0 Appetite depressants [anorectics]	0.633	0.367	0.000
K82.2 Perforation of gallbladder	0.632	0.368	0.000
R94.3 Abnormal results of cardiovascular function studies	0.632	0.368	0.000
J94.8 Other specified pleural conditions	0.632	0.368	0.000
I60 Subarachnoid haemorrhage	0.632	0.368	0.000
I24 Other acute ischaemic heart diseases	0.632	0.368	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.632	0.368	0.000
I27.9 Pulmonary heart disease, unspecified	0.631	0.369	0.000
T18.5 Foreign body in anus and rectum	0.630	0.370	0.000
Y57.5 X-ray contrast media	0.630	0.370	0.000
Y43.4 Immunosuppressive agents	0.629	0.371	0.000
S60 Superficial injury of wrist and hand	0.628	0.372	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.628	0.372	0.000
T88.9 Complication of surgical and medical care, unspecified	0.628	0.372	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.628	0.372	0.000
T88.2 Shock due to anaesthesia	0.628	0.372	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.628	0.372	0.000
T88.0 Infection following immunisation	0.628	0.372	0.000
V80-V89 Other land transport accidents	0.628	0.372	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.628	0.372	0.000
S37 Injury of urinary and pelvic organs	0.627	0.373	0.000
Y54.4 Loop [high-ceiling] diuretics	0.627	0.373	0.000
R25.3 Fasciculation	0.627	0.373	0.000
Y52.1 Calcium-channel blockers	0.627	0.373	0.000
K72 Hepatic failure, not elsewhere classified	0.627	0.373	0.000
I70.9 Generalised and unspecified atherosclerosis	0.626	0.374	0.000
I70.8 Atherosclerosis of other arteries	0.626	0.374	0.000
F40.2 Specific (isolated) phobias	0.625	0.375	0.000
Y40.3 Macrolides	0.624	0.376	0.000
R82.9 Other and unspecified abnormal finding in urine	0.623	0.377	0.000
T20 Burn and corrosion of head and neck	0.623	0.377	0.000
R81 Glycosuria	0.623	0.377	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.622	0.378	0.000
I70.0 Atherosclerosis of aorta	0.622	0.378	0.000
S91 Open wound of ankle and foot	0.619	0.381	0.000
I70.1 Atherosclerosis of renal artery	0.619	0.381	0.000
I42.0 Dilated cardiomyopathy	0.619	0.381	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.618	0.381	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.618	0.382	0.000
T18.4 Foreign body in colon	0.618	0.382	0.000
T18.3 Foreign body in small intestine	0.618	0.382	0.000
T18.2 Foreign body in stomach	0.618	0.382	0.000
T18.0 Foreign body in mouth	0.618	0.382	0.000
F40.9 Phobic anxiety disorder, unspecified	0.618	0.382	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.617	0.383	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.617	0.383	0.000
I42.8 Other cardiomyopathies	0.616	0.384	0.000
I05-I09 Chronic rheumatic heart diseases	0.615	0.385	0.000
F44 Dissociative [conversion] disorders	0.615	0.385	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.614	0.386	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.614	0.386	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.614	0.386	0.000
S32 Fracture of lumbar spine and pelvis	0.614	0.386	0.000
K50.0 Crohn's disease of small intestine	0.613	0.387	0.000
K40 Inguinal hernia	0.612	0.388	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.612	0.388	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.611	0.389	0.000
K92.1 Melaena	0.611	0.389	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.608	0.392	0.000
X60-X84 Intentional self-harm	0.608	0.392	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.606	0.394	0.000
F70-F79 Mental retardation	0.606	0.394	0.000
I77.6 Arteritis, unspecified	0.606	0.394	0.000
S20-S29 Injuries to the thorax	0.605	0.395	0.000
K74.3 Primary biliary cirrhosis	0.604	0.396	0.000
I72.8 Aneurysm of other specified arteries	0.603	0.397	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.603	0.397	0.000
Y43.1 Antineoplastic antimetabolites	0.602	0.398	0.000
R27.8 Other and unspecified lack of coordination	0.601	0.399	0.000
I31.8 Other specified diseases of pericardium	0.601	0.399	0.000
I31.2 Haemopericardium, not elsewhere classified	0.601	0.399	0.000
I31.1 Chronic constrictive pericarditis	0.601	0.399	0.000
I31.0 Chronic adhesive pericarditis	0.601	0.399	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.600	0.400	0.000
K74.4 Secondary biliary cirrhosis	0.600	0.400	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.600	0.400	0.000
K74.1 Hepatic sclerosis	0.600	0.400	0.000
F48 Other neurotic disorders	0.599	0.401	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.599	0.401	0.000
H60 Otitis externa	0.599	0.401	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.598	0.401	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.598	0.402	0.000
H61.8 Other specified disorders of external ear	0.598	0.402	0.000
W22.8 Other specified place	0.597	0.403	0.000
W22.6 Industrial and construction area	0.597	0.403	0.000
W22.4 Street and highway	0.597	0.403	0.000
W22.0 Home	0.597	0.403	0.000
W22.7 Farm	0.597	0.403	0.000
W22.5 Trade and service area	0.597	0.403	0.000
W22.1 Residential institution	0.597	0.403	0.000
I45.4 Nonspecific intraventricular block	0.596	0.403	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.596	0.404	0.000
I50.9 Heart failure, unspecified	0.596	0.404	0.000
S36 Injury of intra-abdominal organs	0.596	0.404	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations