TreeWAS – Variant ID: rs11021499

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O82.0 Delivery by elective Caesarean section	0.000	0.942	0.058
O80 Single spontaneous delivery	0.000	0.951	0.049
O80.9 Single spontaneous delivery, unspecified	0.000	0.951	0.049
O82 Single delivery by Caesarean section	0.000	0.952	0.048
O80-O84 Delivery	0.000	0.954	0.046
O80.0 Spontaneous vertex delivery	0.000	0.954	0.046
O80.8 Other single spontaneous delivery	0.000	0.962	0.038
O80.1 Spontaneous breech delivery	0.000	0.964	0.036
O82.8 Other single delivery by Caesarean section	0.000	0.965	0.035
O82.2 Delivery by Caesarean hysterectomy	0.000	0.965	0.035
O81 Single delivery by forceps and vacuum extractor	0.000	0.965	0.035
O84 Multiple delivery	0.000	0.966	0.033
O83 Other assisted single delivery	0.000	0.966	0.033
O81.0 Low forceps delivery	0.000	0.970	0.030
O82.9 Delivery by Caesarean section, unspecified	0.000	0.973	0.027
O82.1 Delivery by emergency Caesarean section	0.000	0.973	0.027
O81.3 Other and unspecified forceps delivery	0.000	0.974	0.026
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.975	0.025
O81.2 Mid-cavity forceps with rotation	0.000	0.975	0.025
O81.1 Mid-cavity forceps delivery	0.000	0.975	0.025
O83.9 Assisted single delivery, unspecified	0.000	0.976	0.024
O83.8 Other specified assisted single delivery	0.000	0.976	0.024
O83.4 Destructive operation for delivery	0.000	0.976	0.024
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.976	0.024
O83.2 Other manipulation-assisted delivery	0.000	0.976	0.024
O83.1 Other assisted breech delivery	0.000	0.976	0.024
O83.0 Breech extraction	0.000	0.976	0.024
O84.9 Multiple delivery, unspecified	0.000	0.976	0.024
O84.8 Other multiple delivery	0.000	0.976	0.024
O84.2 Multiple delivery, all by Caesarean section	0.000	0.976	0.024
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.976	0.024
O84.0 Multiple delivery, all spontaneous	0.000	0.976	0.024
S00.1 Contusion of eyelid and periocular area	0.022	0.978	0.000
S00 Superficial injury of head	0.017	0.983	0.000
O81.4 Vacuum extractor delivery	0.000	0.983	0.016
S00.7 Multiple superficial injuries of head	0.016	0.984	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.014	0.985	0.000
S00.3 Superficial injury of nose	0.014	0.986	0.000
S00.5 Superficial injury of lip and oral cavity	0.013	0.986	0.000
S00.4 Superficial injury of ear	0.013	0.987	0.000
S00.8 Superficial injury of other parts of head	0.012	0.988	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.011	0.989	0.000
K56.7 Ileus, unspecified	0.010	0.990	0.000
S00.0 Superficial injury of scalp	0.009	0.991	0.000
T88.4 Failed or difficult intubation	0.009	0.991	0.000
I77 Other disorders of arteries and arterioles	0.008	0.992	0.000
I77.0 Arteriovenous fistula, acquired	0.007	0.993	0.000
S00.9 Superficial injury of head, part unspecified	0.007	0.993	0.000
S01.2 Open wound of nose	0.007	0.993	0.000
I77.1 Stricture of artery	0.007	0.993	0.000
I77.8 Other specified disorders of arteries and arterioles	0.006	0.994	0.000
W06.0 Home	0.006	0.994	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
I77.5 Necrosis of artery	0.006	0.994	0.000
I77.4 Coeliac artery compression syndrome	0.006	0.994	0.000
I77.3 Arterial fibromuscular dysplasia	0.006	0.994	0.000
M94.8 Other specified disorders of cartilage	0.006	0.994	0.000
M94.88 Other specified disorders of cartilage (Other)	0.006	0.994	0.000
S83.2 Tear of meniscus, current	0.000	0.994	0.006
S01 Open wound of head	0.006	0.994	0.000
T88.5 Other complications of anaesthesia	0.006	0.994	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.005	0.995	0.000
S01.9 Open wound of head, part unspecified	0.005	0.995	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.005	0.995	0.000
S01.3 Open wound of ear	0.005	0.995	0.000
K10.8 Other specified diseases of jaws	0.000	0.995	0.005
I77.6 Arteritis, unspecified	0.005	0.995	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.995	0.005
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
S00-S09 Injuries to the head	0.005	0.995	0.000
T88.2 Shock due to anaesthesia	0.005	0.995	0.000
N43.3 Hydrocele, unspecified	0.000	0.995	0.005
I77.2 Rupture of artery	0.005	0.995	0.000
S01.0 Open wound of scalp	0.005	0.995	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.005	0.995	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.005	0.995	0.000
E27.2 Addisonian crisis	0.000	0.995	0.005
E27 Other disorders of adrenal gland	0.000	0.995	0.005
M94.89 Other specified disorders of cartilage (Site unspecified)	0.004	0.995	0.000
T88.9 Complication of surgical and medical care, unspecified	0.004	0.995	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.004	0.995	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.004	0.995	0.000
T88.0 Infection following immunisation	0.004	0.995	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.004	0.996	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.004	0.996	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.004	0.996	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.004	0.996	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.004	0.996	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.996	0.004
S01.7 Multiple open wounds of head	0.004	0.996	0.000
S09.8 Other specified injuries of head	0.004	0.996	0.000
S01.4 Open wound of cheek and temporomandibular area	0.004	0.996	0.000
S06 Intracranial injury	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.996	0.004
S08 Traumatic amputation of part of head	0.004	0.996	0.000
S07 Crushing injury of head	0.004	0.996	0.000
S04 Injury of cranial nerves	0.004	0.996	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.996	0.004
S09 Other and unspecified injuries of head	0.004	0.996	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.996	0.004
E23.7 Disorder of pituitary gland, unspecified	0.000	0.996	0.004
S06.0 Concussion	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.004	0.996	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
D22.4 Melanocytic naevi of scalp and neck	0.000	0.996	0.004
F06.7 Mild cognitive disorder	0.004	0.996	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.996	0.000
K10.2 Inflammatory conditions of jaws	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.000	0.996	0.003
E27.0 Other adrenocortical overactivity	0.000	0.996	0.003
M94 Other disorders of cartilage	0.003	0.996	0.000
Z87.8 Personal history of other specified conditions	0.000	0.997	0.003
S06.2 Diffuse brain injury	0.003	0.997	0.000
K10 Other diseases of jaws	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
S01.5 Open wound of lip and oral cavity	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
S09.0 Injury of blood vessels of head, not elsewhere classified	0.003	0.997	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.997	0.003
J30.4 Allergic rhinitis, unspecified	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.003	0.997	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
E24 Cushing's syndrome	0.000	0.997	0.003
L40.0 Psoriasis vulgaris	0.000	0.997	0.003
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
S04.9 Injury of unspecified cranial nerve	0.003	0.997	0.000
S04.8 Injury of other cranial nerves	0.003	0.997	0.000
S04.7 Injury of accessory nerve	0.003	0.997	0.000
S04.6 Injury of acoustic nerve	0.003	0.997	0.000
S04.5 Injury of facial nerve	0.003	0.997	0.000
S04.4 Injury of abducent nerve	0.003	0.997	0.000
S04.3 Injury of trigeminal nerve	0.003	0.997	0.000
S04.2 Injury of trochlear nerve	0.003	0.997	0.000
S04.1 Injury of oculomotor nerve	0.003	0.997	0.000
S04.0 Injury of optic nerve and pathways	0.003	0.997	0.000
S07.9 Crushing injury of head, part unspecified	0.003	0.997	0.000
S07.8 Crushing injury of other parts of head	0.003	0.997	0.000
S07.1 Crushing injury of skull	0.003	0.997	0.000
S07.0 Crushing injury of face	0.003	0.997	0.000
S08.9 Traumatic amputation of unspecified part of head	0.003	0.997	0.000
S08.8 Traumatic amputation of other parts of head	0.003	0.997	0.000
S08.1 Traumatic amputation of ear	0.003	0.997	0.000
S08.0 Avulsion of scalp	0.003	0.997	0.000
S09.7 Multiple injuries of head	0.003	0.997	0.000
S09.1 Injury of muscle and tendon of head	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
G82.4 Spastic tetraplegia	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.003	0.997	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.003	0.997	0.000
S01.1 Open wound of eyelid and periocular area	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
S03.1 Dislocation of septal cartilage of nose	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
Z97.8 Presence of other specified devices	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.003
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.003
K10.3 Alveolitis of jaws	0.000	0.997	0.003
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.003	0.997	0.000
S03.4 Sprain and strain of jaw	0.003	0.997	0.000
S03.3 Dislocation of other and unspecified parts of head	0.003	0.997	0.000
S03.0 Dislocation of jaw	0.003	0.997	0.000
S09.2 Traumatic rupture of ear drum	0.003	0.997	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.003	0.997	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.003	0.997	0.000
M47.82 Other spondylosis (Cervical region)	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
M94.3 Chondrolysis	0.003	0.997	0.000
M94.1 Relapsing polychondritis	0.003	0.997	0.000
M94.2 Chondromalacia	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
K10.1 Giant cell granuloma, central	0.000	0.997	0.003
S06.3 Focal brain injury	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M94.9 Disorder of cartilage, unspecified	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
E34 Other endocrine disorders	0.000	0.997	0.003
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
K36 Other appendicitis	0.003	0.997	0.000
S06.4 Epidural haemorrhage	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.003	0.997	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
E25 Adrenogenital disorders	0.000	0.997	0.003
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
K10.9 Disease of jaws, unspecified	0.000	0.997	0.002
K10.0 Developmental disorders of jaws	0.000	0.997	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.997	0.000
E34.8 Other specified endocrine disorders	0.000	0.997	0.002
E24.8 Other Cushing's syndrome	0.000	0.997	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.002
E24.1 Nelson's syndrome	0.000	0.997	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.997	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.997	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.997	0.002
Z43.6 Attention to other artificial openings of urinary tract	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.002
E31 Polyglandular dysfunction	0.000	0.997	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.002
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
S03.2 Dislocation of tooth	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.002	0.998	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.002	0.998	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.002	0.998	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.002	0.998	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.002	0.998	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.002	0.998	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.002	0.998	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.002	0.998	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.002	0.998	0.000
M94.18 Relapsing polychondritis (Other)	0.002	0.998	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.002	0.998	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.002	0.998	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.002	0.998	0.000
M94.14 Relapsing polychondritis (Hand)	0.002	0.998	0.000
M94.13 Relapsing polychondritis (Forearm)	0.002	0.998	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.002	0.998	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.002	0.998	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.002	0.998	0.000
M94.39 Chondrolysis (Site unspecified)	0.002	0.998	0.000
M94.38 Chondrolysis (Other)	0.002	0.998	0.000
M94.37 Chondrolysis (Ankle and foot)	0.002	0.998	0.000
M94.36 Chondrolysis (Lower leg)	0.002	0.998	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.002	0.998	0.000
M94.34 Chondrolysis (Hand)	0.002	0.998	0.000
M94.33 Chondrolysis (Forearm)	0.002	0.998	0.000
M94.32 Chondrolysis (Upper arm)	0.002	0.998	0.000
M94.31 Chondrolysis (Shoulder region)	0.002	0.998	0.000
M94.30 Chondrolysis (Multiple sites)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
E32 Diseases of thymus	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
W06 Fall involving bed	0.002	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.002	0.998	0.000
M94.28 Chondromalacia (Other)	0.002	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.002	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.002	0.998	0.000
M94.24 Chondromalacia (Hand)	0.002	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.002	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.002	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.002	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
G82.1 Spastic paraplegia	0.002	0.998	0.000
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.002	0.998	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.002	0.998	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.002	0.998	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.002	0.998	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.002	0.998	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.002	0.998	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.002	0.998	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
T50.8 Diagnostic agents	0.002	0.998	0.000
E26 Hyperaldosteronism	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
I42.2 Other hypertrophic cardiomyopathy	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.998	0.000
D37.7 Other digestive organs	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
V18.5 Passenger injured in traffic accident	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.002	0.998	0.000
F06.5 Organic dissociative disorder	0.002	0.998	0.000
F06.4 Organic anxiety disorder	0.002	0.998	0.000
F06.3 Organic mood [affective] disorders	0.002	0.998	0.000
F06.1 Organic catatonic disorder	0.002	0.998	0.000
F06.0 Organic hallucinosis	0.002	0.998	0.000
I72.9 Aneurysm of unspecified site	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
S83.1 Dislocation of knee	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
S83.0 Dislocation of patella	0.000	0.998	0.002
Z96.0 Presence of urogenital implants	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
M47.8 Other spondylosis	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.002
W06.2 School, other institution and public administrative area	0.002	0.998	0.000
W06.8 Other specified place	0.002	0.998	0.000
W06.7 Farm	0.002	0.998	0.000
W06.6 Industrial and construction area	0.002	0.998	0.000
W06.5 Trade and service area	0.002	0.998	0.000
W06.4 Street and highway	0.002	0.998	0.000
W06.3 Sports and athletics area	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
E28 Ovarian dysfunction	0.000	0.998	0.002
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
W06.1 Residential institution	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
M47.84 Other spondylosis (Thoracic region)	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.002
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.002
D37.2 Small intestine	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
E32.9 Disease of thymus, unspecified	0.000	0.998	0.001
J05.1 Acute epiglottitis	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.002	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.998	0.002
L40.8 Other psoriasis	0.000	0.998	0.002
X58.9 Unspecified place	0.000	0.998	0.002
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.998	0.002
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.002
C48.0 Retroperitoneum	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.002	0.998	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.002	0.998	0.000
W06.9 Unspecified place	0.001	0.998	0.000
Y65 Other misadventures during surgical and medical care	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations