TreeWAS – Variant ID: rs11038871

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.9 Chronic ischaemic heart disease, unspecified	0.879	0.121	0.000
I10 Essential (primary) hypertension	0.866	0.134	0.000
I10-I15 Hypertensive diseases	0.842	0.158	0.000
I25 Chronic ischaemic heart disease	0.838	0.162	0.000
I20-I25 Ischaemic heart diseases	0.838	0.162	0.000
Chapter IX Diseases of the circulatory system	0.837	0.163	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.832	0.168	0.000
I27 Other pulmonary heart diseases	0.832	0.168	0.000
I27.0 Primary pulmonary hypertension	0.825	0.175	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.755	0.245	0.000
I22 Subsequent myocardial infarction	0.753	0.247	0.000
I60 Subarachnoid haemorrhage	0.752	0.248	0.000
I60-I69 Cerebrovascular diseases	0.752	0.248	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.724	0.276	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.719	0.281	0.000
I24 Other acute ischaemic heart diseases	0.699	0.301	0.000
I65.2 Occlusion and stenosis of carotid artery	0.692	0.308	0.000
I27.2 Other secondary pulmonary hypertension	0.686	0.314	0.000
I27.8 Other specified pulmonary heart diseases	0.685	0.315	0.000
I27.9 Pulmonary heart disease, unspecified	0.681	0.319	0.000
I11 Hypertensive heart disease	0.681	0.319	0.000
I25.6 Silent myocardial ischaemia	0.665	0.335	0.000
I25.2 Old myocardial infarction	0.662	0.338	0.000
I20 Angina pectoris	0.659	0.341	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.647	0.353	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.640	0.360	0.000
I25.3 Aneurysm of heart	0.615	0.385	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.613	0.387	0.000
I60.8 Other subarachnoid haemorrhage	0.606	0.394	0.000
I00-I02 Acute rheumatic fever	0.604	0.396	0.000
I13 Hypertensive heart and renal disease	0.604	0.396	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.600	0.400	0.000
I27.1 Kyphoscoliotic heart disease	0.597	0.403	0.000
I28 Other diseases of pulmonary vessels	0.593	0.407	0.000
I20.0 Unstable angina	0.589	0.411	0.000
I25.5 Ischaemic cardiomyopathy	0.574	0.426	0.000
I24.1 Dressler's syndrome	0.569	0.431	0.000
I23 Certain current complications following acute myocardial infarction	0.559	0.441	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.554	0.446	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.550	0.450	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.539	0.461	0.000
I20.1 Angina pectoris with documented spasm	0.535	0.465	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.526	0.474	0.000
I65.1 Occlusion and stenosis of basilar artery	0.524	0.476	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.519	0.481	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.519	0.481	0.000
I22.8 Subsequent myocardial infarction of other sites	0.510	0.490	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.505	0.495	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.501	0.498	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.501	0.498	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.499	0.501	0.000
I62 Other nontraumatic intracranial haemorrhage	0.490	0.510	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.489	0.511	0.000
I26 Pulmonary embolism	0.486	0.514	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.485	0.515	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.472	0.528	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.464	0.536	0.000
I25.4 Coronary artery aneurysm	0.457	0.543	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.449	0.551	0.000
I20.8 Other forms of angina pectoris	0.443	0.557	0.000
I00 Rheumatic fever without mention of heart involvement	0.437	0.563	0.000
I02 Rheumatic chorea	0.433	0.567	0.000
I01 Rheumatic fever with heart involvement	0.433	0.567	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.433	0.567	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.433	0.567	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.433	0.567	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.433	0.567	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.425	0.575	0.000
I28.1 Aneurysm of pulmonary artery	0.425	0.575	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.425	0.575	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.422	0.578	0.000
I28.8 Other specified diseases of pulmonary vessels	0.421	0.579	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.405	0.595	0.000
I70 Atherosclerosis	0.404	0.596	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.401	0.599	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.401	0.599	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.401	0.599	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.401	0.599	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.401	0.599	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.401	0.599	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.401	0.599	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.398	0.602	0.000
I15 Secondary hypertension	0.392	0.608	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.391	0.609	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.390	0.610	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.383	0.617	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.378	0.622	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.377	0.623	0.000
I62.1 Nontraumatic extradural haemorrhage	0.365	0.634	0.000
I23.8 Other current complications following acute myocardial infarction	0.358	0.641	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.358	0.642	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.358	0.642	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.358	0.642	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.354	0.646	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.351	0.649	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.351	0.649	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.351	0.649	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.351	0.649	0.000
I80 Phlebitis and thrombophlebitis	0.350	0.650	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.348	0.652	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.335	0.665	0.000
I61 Intracerebral haemorrhage	0.333	0.667	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.331	0.669	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.324	0.676	0.000
I74 Arterial embolism and thrombosis	0.321	0.679	0.000
I68.0 Cerebral amyloid angiopathy	0.318	0.682	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.316	0.684	0.000
I99 Other and unspecified disorders of circulatory system	0.316	0.684	0.000
I12 Hypertensive renal disease	0.315	0.685	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.314	0.686	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.311	0.689	0.000
I01.8 Other acute rheumatic heart disease	0.311	0.689	0.000
I01.2 Acute rheumatic myocarditis	0.311	0.689	0.000
I01.1 Acute rheumatic endocarditis	0.311	0.689	0.000
I01.0 Acute rheumatic pericarditis	0.311	0.689	0.000
I02.9 Rheumatic chorea without heart involvement	0.311	0.689	0.000
I02.0 Rheumatic chorea with heart involvement	0.311	0.689	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.308	0.692	0.000
I70.8 Atherosclerosis of other arteries	0.305	0.695	0.000
I70.1 Atherosclerosis of renal artery	0.302	0.698	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.301	0.699	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.295	0.705	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.294	0.706	0.000
I70.9 Generalised and unspecified atherosclerosis	0.289	0.710	0.000
I72 Other aneurysm	0.287	0.713	0.000
I15.8 Other secondary hypertension	0.281	0.719	0.000
I15.2 Hypertension secondary to endocrine disorders	0.281	0.719	0.000
I15.0 Renovascular hypertension	0.281	0.719	0.000
I67 Other cerebrovascular diseases	0.280	0.720	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.279	0.721	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.275	0.725	0.000
I67.1 Cerebral aneurysm, nonruptured	0.272	0.728	0.000
I74.5 Embolism and thrombosis of iliac artery	0.263	0.737	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.263	0.737	0.000
I72.0 Aneurysm of carotid artery	0.263	0.737	0.000
I70.0 Atherosclerosis of aorta	0.262	0.738	0.000
I61.8 Other intracerebral haemorrhage	0.258	0.742	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.255	0.745	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.255	0.745	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.253	0.746	0.000
I05-I09 Chronic rheumatic heart diseases	0.252	0.748	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.248	0.752	0.000
I78 Diseases of capillaries	0.247	0.752	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.239	0.761	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.237	0.763	0.000
I88 Nonspecific lymphadenitis	0.235	0.764	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.233	0.766	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.233	0.767	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.230	0.770	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.229	0.771	0.000
I72.2 Aneurysm of renal artery	0.229	0.771	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.228	0.772	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.227	0.772	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.227	0.773	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.227	0.773	0.000
I98.0 Cardiovascular syphilis	0.227	0.773	0.000
I77 Other disorders of arteries and arterioles	0.227	0.773	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.226	0.774	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.224	0.776	0.000
I72.1 Aneurysm of artery of upper extremity	0.219	0.781	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.218	0.781	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.217	0.783	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.213	0.787	0.000
I15.9 Seconday hypertension, unspecified	0.211	0.789	0.001
I20.9 Angina pectoris, unspecified	0.211	0.789	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.208	0.791	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.208	0.792	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.208	0.792	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.206	0.794	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.206	0.794	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.206	0.794	0.000
I71 Aortic aneurysm and dissection	0.205	0.795	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.204	0.796	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.203	0.797	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.201	0.799	0.000
I67.5 Moyamoya disease	0.201	0.799	0.000
I67.4 Hypertensive encephalopathy	0.201	0.799	0.000
I67.3 Progressive vascular leukoencephalopathy	0.201	0.799	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.195	0.805	0.000
I15.1 Hypertension secondary to other renal disorders	0.194	0.805	0.001
I09 Other rheumatic heart diseases	0.193	0.807	0.000
I72.9 Aneurysm of unspecified site	0.189	0.811	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.188	0.812	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.184	0.816	0.000
I77.3 Arterial fibromuscular dysplasia	0.184	0.816	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.182	0.818	0.000
I79.1 Aortitis in diseases classified elsewhere	0.182	0.818	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.182	0.818	0.000
I74.8 Embolism and thrombosis of other arteries	0.180	0.820	0.000
I72.8 Aneurysm of other specified arteries	0.179	0.820	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.178	0.822	0.000
I78.9 Disease of capillaries, unspecified	0.178	0.822	0.000
I95 Hypotension	0.177	0.823	0.000
I69 Sequelae of cerebrovascular disease	0.176	0.823	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.176	0.824	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.175	0.824	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.174	0.826	0.000
I06 Rheumatic aortic valve diseases	0.169	0.830	0.001
I88.1 Chronic lymphadenitis, except mesenteric	0.169	0.831	0.000
I82 Other venous embolism and thrombosis	0.168	0.832	0.000
I85 Oesophageal varices	0.168	0.832	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.168	0.832	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.166	0.834	0.000
I07 Rheumatic tricuspid valve diseases	0.165	0.834	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.164	0.836	0.000
I78.8 Other diseases of capillaries	0.163	0.836	0.000
I77.5 Necrosis of artery	0.163	0.837	0.000
I77.4 Coeliac artery compression syndrome	0.163	0.837	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.162	0.838	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.161	0.839	0.000
I88.8 Other nonspecific lymphadenitis	0.160	0.840	0.000
I72.3 Aneurysm of iliac artery	0.156	0.843	0.000
I95.2 Hypotension due to drugs	0.156	0.844	0.000
I77.2 Rupture of artery	0.155	0.845	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.153	0.847	0.000
I09.9 Rheumatic heart disease, unspecified	0.151	0.849	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.150	0.850	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.147	0.853	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.147	0.853	0.000
I86 Varicose veins of other sites	0.147	0.853	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.144	0.855	0.001
I12.9 Hypertensive renal disease without renal failure	0.145	0.855	0.000
I95.8 Other hypotension	0.144	0.856	0.000
I77.0 Arteriovenous fistula, acquired	0.140	0.860	0.000
I09.8 Other specified rheumatic heart diseases	0.138	0.861	0.000
I09.2 Chronic rheumatic pericarditis	0.138	0.861	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.138	0.861	0.000
I09.0 Rheumatic myocarditis	0.138	0.861	0.000
I81 Portal vein thrombosis	0.138	0.862	0.000
I08 Multiple valve diseases	0.137	0.863	0.000
I77.8 Other specified disorders of arteries and arterioles	0.136	0.864	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.133	0.867	0.000
I82.2 Embolism and thrombosis of vena cava	0.132	0.868	0.000
I24.8 Other forms of acute ischaemic heart disease	0.129	0.871	0.000
I87 Other disorders of veins	0.128	0.872	0.000
I08.8 Other multiple valve diseases	0.126	0.874	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.125	0.875	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.122	0.878	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.122	0.878	0.001
I06.8 Other rheumatic aortic valve diseases	0.122	0.878	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.122	0.878	0.001
I06.1 Rheumatic aortic insufficiency	0.122	0.878	0.001
I82.1 Thrombophlebitis migrans	0.121	0.879	0.000
I82.0 Budd-Chiari syndrome	0.121	0.879	0.000
I07.9 Tricuspid valve disease, unspecified	0.119	0.881	0.000
I07.8 Other tricuspid valve diseases	0.119	0.881	0.000
I07.2 Tricuspid stenosis with insufficiency	0.119	0.881	0.000
I07.0 Tricuspid stenosis	0.119	0.881	0.000
I12.0 Hypertensive renal disease with renal failure	0.118	0.882	0.000
I71.0 Dissection of aorta [any part]	0.116	0.884	0.000
I95.0 Idiopathic hypotension	0.116	0.884	0.000
I77.6 Arteritis, unspecified	0.114	0.885	0.000
I83 Varicose veins of lower extremities	0.112	0.888	0.000
I86.3 Vulval varices	0.112	0.888	0.000
I06.0 Rheumatic aortic stenosis	0.110	0.889	0.001
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.110	0.890	0.000
I78.1 Naevus, nonneoplastic	0.108	0.892	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.107	0.893	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.106	0.894	0.000
I86.0 Sublingual varices	0.106	0.894	0.000
I82.8 Embolism and thrombosis of other specified veins	0.105	0.895	0.000
I86.2 Pelvic varices	0.105	0.895	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.104	0.896	0.001
I97.0 Postcardiotomy syndrome	0.104	0.896	0.001
I08.9 Multiple valve disease, unspecified	0.104	0.896	0.000
I07.1 Tricuspid insufficiency	0.103	0.896	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.098	0.901	0.001
I87.1 Compression of vein	0.098	0.902	0.000
I82.3 Embolism and thrombosis of renal vein	0.098	0.902	0.000
I85.0 Oesophageal varices with bleeding	0.096	0.904	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.096	0.904	0.000
I73 Other peripheral vascular diseases	0.095	0.905	0.000
I25.1 Atherosclerotic heart disease	0.094	0.906	0.000
I72.4 Aneurysm of artery of lower extremity	0.092	0.907	0.000
I87.9 Disorder of vein, unspecified	0.092	0.908	0.000
I87.0 Postphlebitic syndrome	0.092	0.908	0.000
I86.4 Gastric varices	0.092	0.908	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.092	0.908	0.000
I85.9 Oesophageal varices without bleeding	0.090	0.910	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.089	0.910	0.000
I86.8 Varicose veins of other specified sites	0.089	0.910	0.000
I69.3 Sequelae of cerebral infarction	0.087	0.913	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.080	0.919	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.080	0.920	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.075	0.925	0.000
I77.1 Stricture of artery	0.074	0.926	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.074	0.926	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.070	0.929	0.001
I67.9 Cerebrovascular disease, unspecified	0.070	0.930	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.069	0.931	0.000
I86.1 Scrotal varices	0.066	0.934	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.065	0.935	0.000
I73.8 Other specified peripheral vascular diseases	0.060	0.940	0.000
I89.1 Lymphangitis	0.059	0.940	0.000
I97.1 Other functional disturbances following cardiac surgery	0.053	0.946	0.001
I87.8 Other specified disorders of veins	0.051	0.949	0.000
I89.0 Lymphoedema, not elsewhere classified	0.047	0.952	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.046	0.954	0.000
I67.2 Cerebral atherosclerosis	0.042	0.956	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.039	0.960	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.037	0.961	0.002
I63 Cerebral infarction	0.034	0.966	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.033	0.967	0.000
I95.1 Orthostatic hypotension	0.033	0.967	0.000
I67.8 Other specified cerebrovascular diseases	0.032	0.968	0.000
I05 Rheumatic mitral valve diseases	0.025	0.971	0.004
I08.0 Disorders of both mitral and aortic valves	0.026	0.974	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.026	0.974	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.024	0.975	0.001
I83.1 Varicose veins of lower extremities with inflammation	0.025	0.975	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.024	0.975	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.024	0.975	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.023	0.977	0.000
D86.9 Sarcoidosis, unspecified	0.022	0.978	0.000
I05.8 Other mitral valve diseases	0.018	0.979	0.003
I73.9 Peripheral vascular disease, unspecified	0.021	0.979	0.000
I21 Acute myocardial infarction	0.021	0.979	0.000
D86.0 Sarcoidosis of lung	0.021	0.979	0.000
D86 Sarcoidosis	0.020	0.980	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.020	0.980	0.000
D35.1 Parathyroid gland	0.019	0.981	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.981	0.019
I95.9 Hypotension, unspecified	0.017	0.983	0.000
D86.8 Sarcoidosis of other and combined sites	0.017	0.983	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.016	0.984	0.000
H65.4 Other chronic nonsuppurative otitis media	0.015	0.985	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.015	0.985	0.000
I05.2 Mitral stenosis with insufficiency	0.011	0.985	0.004
D86.1 Sarcoidosis of lymph nodes	0.015	0.985	0.000
I05.0 Mitral stenosis	0.010	0.987	0.004
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.013	0.987	0.000
I05.1 Rheumatic mitral insufficiency	0.009	0.987	0.005
D35 Benign neoplasm of other and unspecified endocrine glands	0.013	0.987	0.000
D86.3 Sarcoidosis of skin	0.013	0.987	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.013	0.987	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.013	0.987	0.000
H65 Nonsuppurative otitis media	0.013	0.987	0.000
I05.9 Mitral valve disease, unspecified	0.009	0.987	0.004
D35.0 Adrenal gland	0.012	0.988	0.000
I63.8 Other cerebral infarction	0.012	0.988	0.000
I73.0 Raynaud's syndrome	0.012	0.988	0.000
I21.9 Acute myocardial infarction, unspecified	0.012	0.988	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.011	0.989	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.011	0.989	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.010	0.990	0.000
H65.0 Acute serous otitis media	0.010	0.990	0.000
D35.9 Endocrine gland, unspecified	0.010	0.990	0.000
D35.8 Pluriglandular involvement	0.010	0.990	0.000
D35.7 Other specified endocrine glands	0.010	0.990	0.000
D35.6 Aortic body and other paraganglia	0.010	0.990	0.000
D35.5 Carotid body	0.010	0.990	0.000
D35.4 Pineal gland	0.010	0.990	0.000
D35.3 Craniopharyngeal duct	0.010	0.990	0.000
H65.2 Chronic serous otitis media	0.010	0.990	0.000
H65.3 Chronic mucoid otitis media	0.010	0.990	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.009	0.991	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.991	0.009
D35.2 Pituitary gland	0.009	0.991	0.000
H65.1 Other acute nonsuppurative otitis media	0.009	0.991	0.000
D80-D89 Certain disorders involving the immune mechanism	0.009	0.991	0.000
Z29.0 Isolation	0.000	0.991	0.009
M79.0 Rheumatism, unspecified	0.009	0.991	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.992	0.008
J84.1 Other interstitial pulmonary diseases with fibrosis	0.008	0.992	0.000
D82 Immunodeficiency associated with other major defects	0.007	0.993	0.000
Z29 Need for other prophylactic measures	0.000	0.993	0.007
D80 Immunodeficiency with predominantly antibody defects	0.007	0.993	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.993	0.007
Q61.3 Polycystic kidney, unspecified	0.000	0.993	0.007
Q61 Cystic kidney disease	0.000	0.993	0.007
J84 Other interstitial pulmonary diseases	0.007	0.993	0.000
D81 Combined immunodeficiencies	0.006	0.993	0.000
D82.1 Di George's syndrome	0.006	0.994	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.006	0.994	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.006	0.994	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M79.04 Rheumatism, unspecified (Hand)	0.006	0.994	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.006	0.994	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.006	0.994	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.006	0.994	0.000
D32.0 Cerebral meninges	0.006	0.994	0.000
M79.08 Rheumatism, unspecified (Other)	0.006	0.994	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.006	0.994	0.000
J84.0 Alveolar and parietoalveolar conditions	0.006	0.994	0.000
I63.9 Cerebral infarction, unspecified	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
D84 Other immunodeficiencies	0.006	0.994	0.000
Q61.0 Congenital single renal cyst	0.000	0.994	0.006
D83 Common variable immunodeficiency	0.006	0.994	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.006	0.994	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.006	0.994	0.000
M54.39 Sciatica (Site unspecified)	0.006	0.994	0.000
H11.0 Pterygium	0.006	0.994	0.000
J84.8 Other specified interstitial pulmonary diseases	0.006	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.005	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.005	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.005	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.005	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.005	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.005	0.994	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.994	0.005
Q61.5 Medullary cystic kidney	0.000	0.994	0.005
D80.1 Nonfamilial hypogammaglobulinaemia	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
Q61.8 Other cystic kidney diseases	0.000	0.995	0.005
Q61.4 Renal dysplasia	0.000	0.995	0.005
Q61.1 Polycystic kidney, infantile type	0.000	0.995	0.005
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
U89.8 Agent resistant to other single specified antibiotic	0.005	0.995	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.995	0.005
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.005	0.995	0.000
D81.9 Combined immunodeficiency, unspecified	0.005	0.995	0.000
D81.8 Other combined immunodeficiencies	0.005	0.995	0.000
D81.7 Major histocompatibility complex class II deficiency	0.005	0.995	0.000
D81.6 Major histocompatibility complex class I deficiency	0.005	0.995	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.005	0.995	0.000
D81.4 Nezelof's syndrome	0.005	0.995	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.005	0.995	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.005	0.995	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.005	0.995	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.005	0.995	0.000
D89.1 Cryoglobulinaemia	0.005	0.995	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.995	0.005
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.005	0.995	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.995	0.000
D89.3 Immune reconstitution syndrome	0.004	0.995	0.000
D84.8 Other specified immunodeficiencies	0.004	0.995	0.000
D84.1 Defects in the complement system	0.004	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.995	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.995	0.004
D83.8 Other common variable immunodeficiencies	0.004	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.004	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.004	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.004	0.996	0.000
J39.2 Other diseases of pharynx	0.004	0.996	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.996	0.004
Z29.2 Other prophylactic chemotherapy	0.000	0.996	0.004
E21.0 Primary hyperparathyroidism	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.000	0.996	0.004
Q76.0 Spina bifida occulta	0.004	0.996	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.996	0.000
H11 Other disorders of conjunctiva	0.004	0.996	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.996	0.004
D83.9 Common variable immunodeficiency, unspecified	0.003	0.996	0.000
H11.8 Other specified disorders of conjunctiva	0.004	0.996	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.996	0.004
Z29.8 Other specified prophylactic measures	0.000	0.996	0.004
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.996	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.996	0.003
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.996	0.003
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.003	0.997	0.000
H11.2 Conjunctival scars	0.003	0.997	0.000
U89 Agent resistant to other and unspecified antibiotics	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.003	0.997	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.997	0.003
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
I21.4 Acute subendocardial myocardial infarction	0.003	0.997	0.000
M79.9 Soft tissue disorder, unspecified	0.003	0.997	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.000	0.997	0.003
M79.5 Residual foreign body in soft tissue	0.003	0.997	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.003	0.997	0.000
D38.1 Trachea, bronchus and lung	0.003	0.997	0.000
G93.6 Cerebral oedema	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
U89.9 Agent resistant to unspecified antibiotic	0.003	0.997	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.003	0.997	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.997	0.003
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.003	0.997	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.003	0.997	0.000
M65.34 Trigger finger-Hand	0.000	0.997	0.003
M79 Other soft tissue disorders, not elsewhere classified	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.003	0.997	0.000
E83.5 Disorders of calcium metabolism	0.003	0.997	0.000
R29.6 Tendency to fall, not elsewhere classified	0.003	0.997	0.000
H92.0 Otalgia	0.000	0.997	0.003
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.997	0.000
Q76.7 Congenital malformation of sternum	0.002	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.997	0.003
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations