TreeWAS – Variant ID: rs11057864

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I21 Acute myocardial infarction	0.998	0.002	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.997	0.003	0.000
I25.2 Old myocardial infarction	0.992	0.008	0.000
I21.9 Acute myocardial infarction, unspecified	0.987	0.013	0.000
Chapter IX Diseases of the circulatory system	0.984	0.016	0.000
I60-I69 Cerebrovascular diseases	0.983	0.017	0.000
I25.1 Atherosclerotic heart disease	0.980	0.020	0.000
I67 Other cerebrovascular diseases	0.970	0.030	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.964	0.036	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.953	0.047	0.000
S20-S29 Injuries to the thorax	0.949	0.051	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.948	0.052	0.000
I67.9 Cerebrovascular disease, unspecified	0.940	0.060	0.000
I20 Angina pectoris	0.938	0.062	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.934	0.066	0.000
I20.9 Angina pectoris, unspecified	0.928	0.072	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.926	0.074	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.926	0.074	0.000
S20 Superficial injury of thorax	0.914	0.086	0.000
I67.8 Other specified cerebrovascular diseases	0.913	0.087	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.889	0.111	0.000
S50-S59 Injuries to the elbow and forearm	0.887	0.113	0.000
I21.4 Acute subendocardial myocardial infarction	0.879	0.121	0.000
# Top node	0.878	0.122	0.000
S22.0 Fracture of thoracic vertebra	0.872	0.128	0.000
S20.2 Contusion of thorax	0.871	0.129	0.000
Chapter VII Diseases of the eye and adnexa	0.870	0.130	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.849	0.151	0.000
S40-S49 Injuries to the shoulder and upper arm	0.849	0.151	0.000
H30-H36 Disorders of choroid and retina	0.848	0.152	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.841	0.159	0.000
I22 Subsequent myocardial infarction	0.840	0.160	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.839	0.161	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.833	0.167	0.000
S90-S99 Injuries to the ankle and foot	0.827	0.173	0.000
H35 Other retinal disorders	0.827	0.173	0.000
I69 Sequelae of cerebrovascular disease	0.826	0.174	0.000
S22.1 Multiple fractures of thoracic spine	0.821	0.178	0.000
I30-I52 Other forms of heart disease	0.819	0.181	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.818	0.182	0.000
Chapter VIII Diseases of the ear and mastoid process	0.816	0.184	0.000
S80-S89 Injuries to the knee and lower leg	0.813	0.187	0.000
I61 Intracerebral haemorrhage	0.804	0.196	0.000
H25-H28 Disorders of lens	0.798	0.202	0.000
S52 Fracture of forearm	0.796	0.204	0.000
H35.3 Degeneration of macula and posterior pole	0.790	0.210	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.789	0.211	0.000
S22.4 Multiple fractures of ribs	0.779	0.221	0.000
S51 Open wound of forearm	0.778	0.222	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.773	0.227	0.000
S52.6 Fracture of lower end of both ulna and radius	0.773	0.227	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.771	0.229	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.769	0.231	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.767	0.233	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.766	0.234	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.766	0.234	0.000
I31 Other diseases of pericardium	0.762	0.238	0.000
H53-H54 Visual disturbances and blindness	0.759	0.241	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.757	0.243	0.000
I45 Other conduction disorders	0.754	0.246	0.000
S32 Fracture of lumbar spine and pelvis	0.754	0.246	0.000
H65-H75 Diseases of middle ear and mastoid	0.753	0.247	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.751	0.249	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.746	0.254	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.744	0.256	0.000
T36 Poisoning by systemic antibiotics	0.741	0.259	0.000
I65.2 Occlusion and stenosis of carotid artery	0.740	0.260	0.000
T39.1 4-Aminophenol derivatives	0.740	0.260	0.000
T39.0 Salicylates	0.732	0.268	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.727	0.273	0.000
I49 Other cardiac arrhythmias	0.722	0.278	0.000
S27 Injury of other and unspecified intrathoracic organs	0.720	0.280	0.000
I67.2 Cerebral atherosclerosis	0.719	0.281	0.000
H25 Senile cataract	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
I31.9 Disease of pericardium, unspecified	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.716	0.284	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.716	0.284	0.000
S81 Open wound of lower leg	0.714	0.286	0.000
H60-H62 Diseases of external ear	0.713	0.287	0.000
S40 Superficial injury of shoulder and upper arm	0.711	0.289	0.000
I46 Cardiac arrest	0.711	0.289	0.000
S92 Fracture of foot, except ankle	0.710	0.290	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.710	0.290	0.000
H35.0 Background retinopathy and retinal vascular changes	0.708	0.292	0.000
S10-S19 Injuries to the neck	0.707	0.293	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.706	0.294	0.000
I00-I02 Acute rheumatic fever	0.705	0.294	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.705	0.295	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.705	0.295	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.702	0.298	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.702	0.298	0.000
T79-T79 Certain early complications of trauma	0.701	0.299	0.000
H25.8 Other senile cataract	0.698	0.302	0.000
I47 Paroxysmal tachycardia	0.696	0.304	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.696	0.304	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.696	0.304	0.000
I67.5 Moyamoya disease	0.696	0.304	0.000
I67.4 Hypertensive encephalopathy	0.696	0.304	0.000
I67.3 Progressive vascular leukoencephalopathy	0.696	0.304	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.695	0.305	0.000
H36 Retinal disorders in diseases classified elsewhere	0.694	0.306	0.000
T45.2 Vitamins, not elsewhere classified	0.691	0.309	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.690	0.310	0.000
I33 Acute and subacute endocarditis	0.689	0.311	0.000
H43-H45 Disorders of vitreous body and globe	0.685	0.315	0.000
S22.2 Fracture of sternum	0.685	0.315	0.000
T42.1 Iminostilbenes	0.684	0.316	0.000
T33-T35 Frostbite	0.683	0.317	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.683	0.317	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.683	0.317	0.000
T00-T07 Injuries involving multiple body regions	0.683	0.317	0.000
I22.8 Subsequent myocardial infarction of other sites	0.683	0.317	0.000
I62 Other nontraumatic intracranial haemorrhage	0.681	0.319	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.681	0.319	0.000
S26 Injury of heart	0.681	0.319	0.000
S25 Injury of blood vessels of thorax	0.681	0.319	0.000
S24 Injury of nerves and spinal cord at thorax level	0.681	0.319	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.681	0.319	0.000
S21 Open wound of thorax	0.681	0.319	0.000
S22.5 Flail chest	0.681	0.319	0.000
H74 Other disorders of middle ear and mastoid	0.680	0.320	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.680	0.320	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.679	0.320	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.679	0.320	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.679	0.320	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.679	0.320	0.000
H53 Visual disturbances	0.679	0.321	0.000
S51.9 Open wound of forearm, part unspecified	0.673	0.327	0.000
I25.3 Aneurysm of heart	0.673	0.327	0.000
S22.40 Multiple fractures of ribs (closed)	0.673	0.327	0.000
H26 Other cataract	0.672	0.328	0.000
I60 Subarachnoid haemorrhage	0.671	0.329	0.000
S80 Superficial injury of lower leg	0.671	0.329	0.000
H35.7 Separation of retinal layers	0.670	0.330	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.667	0.333	0.000
H10-H13 Disorders of conjunctiva	0.665	0.335	0.000
S22.9 Fracture of bony thorax, part unspecified	0.664	0.336	0.000
S22.8 Fracture of other parts of bony thorax	0.664	0.336	0.000
Q80-Q89 Other congenital malformations	0.664	0.336	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.662	0.338	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.659	0.341	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.659	0.341	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.659	0.341	0.000
S29 Other and unspecified injuries of thorax	0.658	0.342	0.000
S41 Open wound of shoulder and upper arm	0.658	0.342	0.000
S20.7 Multiple superficial injuries of thorax	0.656	0.344	0.000
S20.4 Other superficial injuries of back wall of thorax	0.656	0.344	0.000
S20.3 Other superficial injuries of front wall of thorax	0.656	0.344	0.000
S20.1 Other and unspecified superficial injuries of breast	0.656	0.344	0.000
S20.0 Contusion of breast	0.656	0.344	0.000
S86 Injury of muscle and tendon at lower leg level	0.653	0.347	0.000
I69.3 Sequelae of cerebral infarction	0.652	0.348	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.651	0.349	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.651	0.349	0.000
S36 Injury of intra-abdominal organs	0.650	0.350	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.649	0.351	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.649	0.351	0.000
I45.5 Other specified heart block	0.645	0.355	0.000
I61.8 Other intracerebral haemorrhage	0.644	0.356	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.643	0.357	0.000
S51.0 Open wound of elbow	0.641	0.359	0.000
H34 Retinal vascular occlusions	0.641	0.359	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.640	0.359	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.638	0.362	0.000
H70 Mastoiditis and related conditions	0.637	0.363	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.637	0.363	0.000
T39.4 Antirheumatics, not elsewhere classified	0.637	0.363	0.000
T39.2 Pyrazolone derivatives	0.637	0.363	0.000
H35.6 Retinal haemorrhage	0.637	0.363	0.000
I45.6 Preexcitation syndrome	0.637	0.363	0.000
Q00-Q07 Congenital malformations of the nervous system	0.637	0.363	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.636	0.363	0.000
S59 Other and unspecified injuries of forearm	0.636	0.364	0.000
S58 Traumatic amputation of forearm	0.636	0.364	0.000
S57 Crushing injury of forearm	0.636	0.364	0.000
S56 Injury of muscle and tendon at forearm level	0.636	0.364	0.000
S55 Injury of blood vessels at forearm level	0.636	0.364	0.000
S54 Injury of nerves at forearm level	0.636	0.364	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.636	0.364	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.636	0.364	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.636	0.364	0.000
H61 Other disorders of external ear	0.634	0.366	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.634	0.366	0.000
I49.0 Ventricular fibrillation and flutter	0.634	0.366	0.000
H31 Other disorders of choroid	0.633	0.367	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.631	0.369	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.630	0.370	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.629	0.371	0.000
H35.9 Retinal disorder, unspecified	0.628	0.371	0.000
H73 Other disorders of tympanic membrane	0.628	0.372	0.000
I30 Acute pericarditis	0.627	0.373	0.000
H46 Optic neuritis	0.627	0.373	0.000
I47.2 Ventricular tachycardia	0.626	0.374	0.000
S22.01 Fracture of thoracic vertebra (open)	0.625	0.375	0.000
S32.3 Fracture of ilium	0.625	0.375	0.000
T45.5 Anticoagulants	0.623	0.377	0.000
I46.0 Cardiac arrest with successful resuscitation	0.623	0.377	0.000
H35.5 Hereditary retinal dystrophy	0.620	0.380	0.000
S32.4 Fracture of acetabulum	0.616	0.384	0.000
S91 Open wound of ankle and foot	0.614	0.386	0.000
H72 Perforation of tympanic membrane	0.614	0.386	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.613	0.387	0.000
I49.8 Other specified cardiac arrhythmias	0.610	0.389	0.000
T93 Sequelae of injuries of lower limb	0.610	0.390	0.000
S81.8 Open wound of other parts of lower leg	0.610	0.390	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.609	0.391	0.000
S37 Injury of urinary and pelvic organs	0.609	0.391	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.609	0.391	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.609	0.391	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.609	0.391	0.000
S31 Open wound of abdomen, lower back and pelvis	0.609	0.391	0.000
Chapter VI Diseases of the nervous system	0.609	0.391	0.000
S48 Traumatic amputation of shoulder and upper arm	0.608	0.391	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.608	0.391	0.000
S44 Injury of nerves at shoulder and upper arm level	0.608	0.391	0.000
S47 Crushing injury of shoulder and upper arm	0.608	0.391	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.608	0.392	0.000
H30 Chorioretinal inflammation	0.608	0.392	0.000
H80-H83 Diseases of inner ear	0.607	0.392	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.603	0.397	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.603	0.397	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.603	0.397	0.000
I65.1 Occlusion and stenosis of basilar artery	0.603	0.397	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.603	0.397	0.000
S52.8 Fracture of other parts of forearm	0.602	0.398	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.601	0.399	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.601	0.399	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.601	0.399	0.000
T42.3 Barbiturates	0.601	0.399	0.000
T42.2 Succinimides and oxazolidinediones	0.601	0.399	0.000
T42.0 Hydantoin derivatives	0.601	0.399	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.601	0.399	0.000
Q50-Q56 Congenital malformations of genital organs	0.601	0.399	0.000
I20.1 Angina pectoris with documented spasm	0.601	0.399	0.000
I45.4 Nonspecific intraventricular block	0.600	0.400	0.000
S92.0 Fracture of calcaneus	0.600	0.400	0.000
H25.1 Senile nuclear cataract	0.598	0.402	0.000
I33.0 Acute and subacute infective endocarditis	0.596	0.404	0.000
H53.1 Subjective visual disturbances	0.596	0.404	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.595	0.405	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.594	0.405	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.594	0.406	0.000
S99 Other and unspecified injuries of ankle and foot	0.593	0.407	0.000
S98 Traumatic amputation of ankle and foot	0.593	0.407	0.000
S97 Crushing injury of ankle and foot	0.593	0.407	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.593	0.407	0.000
S95 Injury of blood vessels at ankle and foot level	0.593	0.407	0.000
S94 Injury of nerves at ankle and foot level	0.593	0.407	0.000
S81.9 Open wound of lower leg, part unspecified	0.593	0.407	0.000
H35.2 Other proliferative retinopathy	0.593	0.407	0.000
H35.1 Retinopathy of prematurity	0.593	0.407	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.592	0.408	0.000
T36.0 Penicillins	0.592	0.408	0.000
I45.8 Other specified conduction disorders	0.591	0.409	0.000
S50 Superficial injury of forearm	0.591	0.409	0.000
T98 Sequelae of other and unspecified effects of external causes	0.591	0.409	0.000
Q89 Other congenital malformations, not elsewhere classified	0.590	0.409	0.000
H53.4 Visual field defects	0.590	0.410	0.000
T92 Sequelae of injuries of upper limb	0.590	0.410	0.000
T63 Toxic effect of contact with venomous animals	0.589	0.411	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.589	0.411	0.000
I52 Other heart disorders in diseases classified elsewhere	0.587	0.413	0.000
I48 Atrial fibrillation and flutter	0.587	0.413	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.587	0.413	0.000
I41 Myocarditis in diseases classified elsewhere	0.587	0.413	0.000
I40 Acute myocarditis	0.587	0.413	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.587	0.413	0.000
I37 Pulmonary valve disorders	0.587	0.413	0.000
I36 Nonrheumatic tricuspid valve disorders	0.587	0.413	0.000
I32 Pericarditis in diseases classified elsewhere	0.587	0.413	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.587	0.413	0.000
T45.8 Other primarily systemic and haematological agents	0.587	0.413	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.587	0.413	0.000
T45.6 Fibrinolysis-affecting drugs	0.587	0.413	0.000
T45.4 Iron and its compounds	0.587	0.413	0.000
T45.3 Enzymes, not elsewhere classified	0.587	0.413	0.000
H55-H59 Other disorders of eye and adnexa	0.586	0.414	0.000
I49.9 Cardiac arrhythmia, unspecified	0.585	0.415	0.000
H36.0 Diabetic retinopathy	0.584	0.416	0.000
H74.0 Tympanosclerosis	0.583	0.417	0.000
S88 Traumatic amputation of lower leg	0.583	0.417	0.000
S87 Crushing injury of lower leg	0.583	0.417	0.000
S85 Injury of blood vessels at lower leg level	0.583	0.417	0.000
S84 Injury of nerves at lower leg level	0.583	0.417	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.581	0.419	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.576	0.423	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.576	0.423	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.576	0.423	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.576	0.423	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.576	0.423	0.000
S32.0 Fracture of lumbar vertebra	0.576	0.424	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.574	0.426	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.574	0.426	0.000
I49.3 Ventricular premature depolarisation	0.573	0.427	0.000
I45.9 Conduction disorder, unspecified	0.573	0.427	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.572	0.428	0.000
I25.5 Ischaemic cardiomyopathy	0.572	0.428	0.000
I45.2 Bifascicular block	0.571	0.428	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.571	0.429	0.000
S52.9 Fracture of forearm, part unspecified	0.571	0.429	0.000
S52.7 Multiple fractures of forearm	0.571	0.429	0.000
S52.4 Fracture of shafts of both ulna and radius	0.571	0.429	0.000
S52.3 Fracture of shaft of radius	0.571	0.429	0.000
S52.2 Fracture of shaft of ulna	0.571	0.429	0.000
H53.8 Other visual disturbances	0.570	0.429	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.569	0.431	0.000
S90 Superficial injury of ankle and foot	0.569	0.431	0.000
Chapter XX External causes of morbidity and mortality	0.568	0.432	0.000
Chapter I Certain infectious and parasitic diseases	0.565	0.435	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.564	0.436	0.000
I31.3 Pericardial effusion (noninflammatory)	0.563	0.437	0.000
H26.9 Cataract, unspecified	0.561	0.439	0.000
S52.1 Fracture of upper end of radius	0.560	0.440	0.000
S27.3 Other injuries of lung	0.558	0.441	0.000
S22.41 Multiple fractures of ribs (open)	0.558	0.442	0.000
S70-S79 Injuries to the hip and thigh	0.558	0.442	0.000
S51.7 Multiple open wounds of forearm	0.558	0.442	0.000
H61.0 Perichondritis of external ear	0.558	0.442	0.000
H26.8 Other specified cataract	0.558	0.442	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.557	0.443	0.000
T43.9 Psychotropic drug, unspecified	0.554	0.446	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.554	0.446	0.000
T43.6 Psychostimulants with abuse potential	0.554	0.446	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.554	0.446	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.554	0.446	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.554	0.446	0.000
H70.9 Mastoiditis, unspecified	0.554	0.446	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.551	0.449	0.000
T50.8 Diagnostic agents	0.551	0.449	0.000
T50.7 Analeptics and opioid receptor antagonists	0.551	0.449	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.551	0.449	0.000
T50.5 Appetite depressants	0.551	0.449	0.000
T50.4 Drugs affecting uric acid metabolism	0.551	0.449	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.551	0.449	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.551	0.449	0.000
T50.1 Loop [high-ceiling] diuretics	0.551	0.449	0.000
T50.0 Mineralocorticoids and their antagonists	0.551	0.449	0.000
T95 Sequelae of burns, corrosions and frostbite	0.550	0.450	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.550	0.450	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.550	0.450	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.549	0.450	0.000
Q35-Q37 Cleft lip and cleft palate	0.549	0.450	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.549	0.450	0.000
S80.0 Contusion of knee	0.549	0.450	0.000
H35.8 Other specified retinal disorders	0.549	0.451	0.000
S27.1 Traumatic haemothorax	0.548	0.451	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.547	0.453	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.547	0.453	0.000
I31.8 Other specified diseases of pericardium	0.546	0.454	0.000
I31.2 Haemopericardium, not elsewhere classified	0.546	0.454	0.000
I31.1 Chronic constrictive pericarditis	0.546	0.454	0.000
I31.0 Chronic adhesive pericarditis	0.546	0.454	0.000
H54 Blindness and low vision	0.545	0.455	0.000
Q05 Spina bifida	0.544	0.456	0.000
I05-I09 Chronic rheumatic heart diseases	0.543	0.456	0.000
H20 Iridocyclitis	0.543	0.456	0.000
S42 Fracture of shoulder and upper arm	0.543	0.457	0.000
H43 Disorders of vitreous body	0.543	0.457	0.000
S89 Other and unspecified injuries of lower leg	0.541	0.459	0.000
H27 Other disorders of lens	0.541	0.459	0.000
I45.3 Trifascicular block	0.541	0.459	0.000
I45.0 Right fascicular block	0.541	0.459	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.541	0.459	0.000
S32.2 Fracture of coccyx	0.541	0.459	0.000
S40.0 Contusion of shoulder and upper arm	0.540	0.460	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.540	0.460	0.000
H68 Eustachian salpingitis and obstruction	0.540	0.460	0.000
H67 Otitis media in diseases classified elsewhere	0.540	0.460	0.000
T51 Toxic effect of alcohol	0.539	0.461	0.000
H73.8 Other specified disorders of tympanic membrane	0.538	0.462	0.000
Q89.2 Congenital malformations of other endocrine glands	0.538	0.462	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.538	0.462	0.000
I20.0 Unstable angina	0.538	0.462	0.000
S80.8 Other superficial injuries of lower leg	0.537	0.463	0.000
S92.2 Fracture of other tarsal bone(s)	0.536	0.463	0.000
T40.6 Other and unspecified narcotics	0.536	0.464	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.535	0.465	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.535	0.465	0.000
S92.3 Fracture of metatarsal bone	0.534	0.466	0.000
S27.2 Traumatic heamopneumothorax	0.533	0.466	0.000
S12 Fracture of neck	0.533	0.467	0.000
T65 Toxic effect of other and unspecified substances	0.533	0.467	0.000
T62 Toxic effect of other noxious substances eaten as food	0.533	0.467	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.533	0.467	0.000
T60 Toxic effect of pesticides	0.533	0.467	0.000
T59 Toxic effect of other gases, fumes and vapours	0.533	0.467	0.000
T57 Toxic effect of other inorganic substances	0.533	0.467	0.000
T56 Toxic effect of metals	0.533	0.467	0.000
T54 Toxic effect of corrosive substances	0.533	0.467	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.533	0.467	0.000
T52 Toxic effect of organic solvents	0.533	0.467	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.533	0.467	0.000
T58 Toxic effect of carbon monoxide	0.533	0.467	0.000
T55 Toxic effect of soaps and detergents	0.533	0.467	0.000
I46.9 Cardiac arrest, unspecified	0.533	0.467	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.533	0.467	0.000
S32.30 Fracture of ilium (closed)	0.532	0.468	0.000
H74.4 Polyp of middle ear	0.532	0.468	0.000
T36.9 Systemic antibiotic, unspecified	0.531	0.469	0.000
T36.8 Other systemic antibiotics	0.531	0.469	0.000
T36.7 Antifungal antibiotics, systemically used	0.531	0.469	0.000
T36.6 Rifamycins	0.531	0.469	0.000
T36.5 Aminoglycosides	0.531	0.469	0.000
T36.4 Tetracyclines	0.531	0.469	0.000
T36.3 Macrolides	0.531	0.469	0.000
T36.2 Chloramphenicol group	0.531	0.469	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.531	0.469	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.530	0.470	0.000
H61.9 Disorder of external ear, unspecified	0.529	0.471	0.000
T91 Sequelae of injuries of neck and trunk	0.529	0.471	0.000
H26.0 Infantile, juvenile and presenile cataract	0.525	0.475	0.000
S32.1 Fracture of sacrum	0.524	0.476	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.524	0.476	0.000
T45.0 Antiallergic and antiemetic drugs	0.524	0.476	0.000
H11 Other disorders of conjunctiva	0.524	0.476	0.000
S14 Injury of nerves and spinal cord at neck level	0.523	0.476	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.523	0.477	0.000
S22.3 Fracture of rib	0.523	0.477	0.000
H60 Otitis externa	0.522	0.477	0.000
I49.4 Other and unspecified premature depolarisation	0.521	0.478	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.521	0.478	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.521	0.479	0.000
S41.0 Open wound of shoulder	0.521	0.479	0.000
S92.00 Fracture of calcaneus (closed)	0.521	0.479	0.000
S93.1 Dislocation of toe(s)	0.520	0.479	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.520	0.480	0.000
T66-T78 Other and unspecified effects of external causes	0.519	0.480	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.519	0.481	0.000
I51 Complications and ill-defined descriptions of heart disease	0.519	0.481	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.518	0.481	0.001
S30.1 Contusion of abdominal wall	0.518	0.482	0.000
S32.40 Fracture of acetabulum (closed)	0.518	0.482	0.000
I49.2 Junctional premature depolarisation	0.517	0.482	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.517	0.483	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.517	0.483	0.000
S27.9 Injury of unspecified intrathoracic organ	0.516	0.484	0.000
S27.8 Injury of other specified intrathoracic organs	0.516	0.484	0.000
S27.7 Multiple injuries of intrathoracic organs	0.516	0.484	0.000
S27.6 Injury of pleura	0.516	0.484	0.000
S27.5 Injury of thoracic trachea	0.516	0.484	0.000
S27.4 Injury of bronchus	0.516	0.484	0.000
S51.8 Open wound of other parts of forearm	0.515	0.485	0.000
T42.4 Benzodiazepines	0.515	0.485	0.000
H25.2 Senile cataract, morgagnian type	0.514	0.486	0.000
I23.8 Other current complications following acute myocardial infarction	0.514	0.486	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.514	0.486	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.514	0.486	0.000
Q60-Q64 Congenital malformations of the urinary system	0.513	0.487	0.000
I72 Other aneurysm	0.513	0.487	0.000
S81.7 Multiple open wounds of lower leg	0.512	0.488	0.000
S22.20 Fracture of sternum (closed)	0.512	0.488	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.511	0.489	0.000
I63 Cerebral infarction	0.511	0.489	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.510	0.490	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.510	0.490	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.510	0.490	0.000
I46.1 Sudden cardiac death, so described	0.509	0.490	0.000
S92.9 Fracture of foot, unspecified	0.509	0.491	0.000
S92.7 Multiple fractures of foot	0.509	0.491	0.000
S92.5 Fracture of other toe	0.509	0.491	0.000
S92.4 Fracture of great toe	0.509	0.491	0.000
S92.1 Fracture of talus	0.509	0.491	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.509	0.491	0.000
H65 Nonsuppurative otitis media	0.509	0.491	0.000
S36.1 Injury of liver or gallbladder	0.507	0.492	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.507	0.493	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.507	0.493	0.000
S17 Crushing injury of neck	0.507	0.493	0.000
S15 Injury of blood vessels at neck level	0.507	0.493	0.000
S11 Open wound of neck	0.507	0.493	0.000
S18 Traumatic amputation at neck level	0.507	0.493	0.000
S16 Injury of muscle and tendon at neck level	0.507	0.493	0.000
H72.0 Central perforation of tympanic membrane	0.506	0.494	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.506	0.494	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.506	0.494	0.000
T47.7 Emetics	0.506	0.494	0.000
T47.6 Antidiarrhoeal drugs	0.506	0.494	0.000
T47.5 Digestants	0.506	0.494	0.000
T47.4 Other laxatives	0.506	0.494	0.000
T47.3 Saline and osmotic laxatives	0.506	0.494	0.000
T47.2 Stimulant laxatives	0.506	0.494	0.000
T47.0 Histamine H(2)-receptor antagonists	0.506	0.494	0.000
I02 Rheumatic chorea	0.506	0.494	0.000
I01 Rheumatic fever with heart involvement	0.506	0.494	0.000
I00 Rheumatic fever without mention of heart involvement	0.506	0.494	0.000
H44 Disorders of globe	0.506	0.494	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.505	0.494	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.505	0.494	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.505	0.494	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations