TreeWAS – Variant ID: rs11065028

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H74 Other disorders of middle ear and mastoid	0.113	0.887	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.108	0.892	0.000
H74.0 Tympanosclerosis	0.105	0.895	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.098	0.902	0.000
H65-H75 Diseases of middle ear and mastoid	0.094	0.906	0.000
H74.1 Adhesive middle ear disease	0.092	0.908	0.000
H74.4 Polyp of middle ear	0.088	0.911	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.087	0.913	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.085	0.915	0.000
H72 Perforation of tympanic membrane	0.079	0.921	0.000
H65 Nonsuppurative otitis media	0.079	0.921	0.000
H70 Mastoiditis and related conditions	0.077	0.923	0.000
H71 Cholesteatoma of middle ear	0.077	0.923	0.000
H69 Other disorders of Eustachian tube	0.076	0.924	0.000
H72.8 Other perforations of tympanic membrane	0.076	0.924	0.000
H65.4 Other chronic nonsuppurative otitis media	0.074	0.926	0.000
H68 Eustachian salpingitis and obstruction	0.068	0.932	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.068	0.932	0.000
H67 Otitis media in diseases classified elsewhere	0.068	0.932	0.000
H70.8 Other mastoiditis and related conditions	0.066	0.934	0.000
H70.1 Chronic mastoiditis	0.065	0.935	0.000
H65.1 Other acute nonsuppurative otitis media	0.063	0.937	0.000
H65.0 Acute serous otitis media	0.062	0.938	0.000
H72.0 Central perforation of tympanic membrane	0.062	0.938	0.000
H69.9 Eustachian tube disorder, unspecified	0.060	0.940	0.000
H69.8 Other specified disorders of Eustachian tube	0.059	0.941	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.056	0.944	0.000
H72.1 Attic perforation of tympanic membrane	0.056	0.944	0.000
H70.2 Petrositis	0.056	0.944	0.000
H69.0 Patulous Eustachian tube	0.055	0.945	0.000
H72.2 Other marginal perforations of tympanic membrane	0.054	0.946	0.000
H73 Other disorders of tympanic membrane	0.052	0.948	0.000
H91.8 Other specified hearing loss	0.052	0.948	0.000
H90-H95 Other disorders of ear	0.052	0.948	0.000
H91 Other hearing loss	0.051	0.949	0.000
Chapter VIII Diseases of the ear and mastoid process	0.051	0.949	0.000
H92 Otalgia and effusion of ear	0.050	0.950	0.000
H68.1 Obstruction of Eustachian tube	0.049	0.950	0.000
H92.1 Otorrhoea	0.049	0.951	0.000
H68.0 Eustachian salpingitis	0.049	0.951	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.049	0.951	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.049	0.951	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.049	0.951	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.049	0.951	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.049	0.951	0.000
H91.3 Deaf mutism, not elsewhere classified	0.048	0.952	0.000
H70.0 Acute mastoiditis	0.048	0.952	0.000
H70.9 Mastoiditis, unspecified	0.047	0.953	0.000
H65.2 Chronic serous otitis media	0.046	0.954	0.000
H66 Suppurative and unspecified otitis media	0.045	0.955	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.045	0.955	0.000
H91.2 Sudden idiopathic hearing loss	0.040	0.960	0.000
H92.2 Otorrhagia	0.040	0.960	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.039	0.961	0.000
H73.0 Acute myringitis	0.039	0.961	0.000
H66.4 Suppurative otitis media, unspecified	0.038	0.962	0.000
H73.1 Chronic myringitis	0.038	0.962	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.037	0.963	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.036	0.964	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.036	0.964	0.000
H91.1 Presbycusis	0.036	0.964	0.000
H95.1 Other disorders following mastoidectomy	0.036	0.964	0.000
H66.0 Acute suppurative otitis media	0.036	0.964	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.034	0.966	0.000
H92.0 Otalgia	0.033	0.967	0.000
H91.0 Ototoxic hearing loss	0.030	0.970	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.030	0.970	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.027	0.973	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.027	0.973	0.000
H66.9 Otitis media, unspecified	0.026	0.974	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.022	0.977	0.000
H65.3 Chronic mucoid otitis media	0.023	0.977	0.000
D75.1 Secondary polycythaemia	0.000	0.981	0.019
H90 Conductive and sensorineural hearing loss	0.017	0.983	0.000
H90.3 Sensorineural hearing loss, bilateral	0.014	0.986	0.000
H93 Other disorders of ear, not elsewhere classified	0.014	0.986	0.000
H90.2 Conductive hearing loss, unspecified	0.014	0.986	0.000
H60-H62 Diseases of external ear	0.013	0.986	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.986	0.014
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.014	0.986	0.000
H80-H83 Diseases of inner ear	0.013	0.987	0.000
H73.8 Other specified disorders of tympanic membrane	0.012	0.987	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.012	0.987	0.000
F40.2 Specific (isolated) phobias	0.000	0.988	0.012
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.012	0.988	0.000
H66.3 Other chronic suppurative otitis media	0.011	0.989	0.000
S02.60 Fracture of mandible (closed)	0.011	0.989	0.000
H93.2 Other abnormal auditory perceptions	0.011	0.989	0.000
H93.0 Degenerative and vascular disorders of ear	0.010	0.989	0.000
H93.3 Disorders of acoustic nerve	0.010	0.990	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.010	0.990	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.990	0.010
H62 Disorders of external ear in diseases classified elsewhere	0.009	0.990	0.001
H80 Otosclerosis	0.009	0.991	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.991	0.009
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.008	0.991	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.991	0.009
H93.9 Disorder of ear, unspecified	0.008	0.992	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.992	0.008
H93.8 Other specified disorders of ear	0.008	0.992	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
I47.2 Ventricular tachycardia	0.008	0.992	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.992	0.008
C49.9 Connective and soft tissue, unspecified	0.000	0.992	0.008
H90.0 Conductive hearing loss, bilateral	0.008	0.992	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.992	0.008
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.993	0.007
C49.4 Connective and soft tissue of abdomen	0.000	0.993	0.007
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.993	0.007
C49.5 Connective and soft tissue of pelvis	0.000	0.993	0.007
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.993	0.007
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.993	0.007
H72.9 Perforation of tympanic membrane, unspecified	0.007	0.993	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.007	0.993	0.001
H62.4 Otitis externa in other diseases classified elsewhere	0.007	0.993	0.001
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.007	0.993	0.001
H62.2 Otitis externa in mycoses	0.007	0.993	0.001
H62.1 Otitis externa in viral diseases classified elsewhere	0.007	0.993	0.001
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.993	0.007
N83.0 Follicular cyst of ovary	0.007	0.993	0.000
H91.9 Hearing loss, unspecified	0.007	0.993	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.993	0.007
H80.8 Other otosclerosis	0.007	0.993	0.000
H60 Otitis externa	0.007	0.993	0.000
H80.2 Cochlear otosclerosis	0.006	0.993	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.006	0.993	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.006	0.993	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.993	0.007
D75.2 Essential thrombocytosis	0.000	0.993	0.007
R49.0 Dysphonia	0.007	0.993	0.000
Y42.4 Oral contraceptives	0.000	0.993	0.007
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.006	0.993	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.993	0.006
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.994	0.006
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.994	0.006
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.994	0.006
D75.0 Familial erythrocytosis	0.000	0.994	0.006
H90.5 Sensorineural hearing loss, unspecified	0.006	0.994	0.000
H60.3 Other infective otitis externa	0.006	0.994	0.000
H80.9 Otosclerosis, unspecified	0.005	0.995	0.000
H60.8 Other otitis externa	0.005	0.995	0.000
Y42.2 Antithyroid drugs	0.000	0.995	0.005
H83 Other diseases of inner ear	0.005	0.995	0.000
H60.2 Malignant otitis externa	0.005	0.995	0.000
H60.4 Cholesteatoma of external ear	0.005	0.995	0.000
S02.6 Fracture of mandible	0.005	0.995	0.000
H60.5 Acute otitis externa, non-infective	0.005	0.995	0.000
H60.0 Abscess of external ear	0.004	0.995	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.995	0.005
F40 Phobic anxiety disorders	0.000	0.995	0.005
Z63.5 Disruption of family by separation and divorce	0.000	0.996	0.004
K74.3 Primary biliary cirrhosis	0.000	0.996	0.004
H83.8 Other specified diseases of inner ear	0.004	0.996	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.996	0.004
B37.8 Candidiasis of other sites	0.000	0.996	0.004
Z63.0 Problems in relationship with spouse or partner	0.000	0.996	0.004
K74 Fibrosis and cirrhosis of liver	0.000	0.996	0.004
Z63 Other problems related to primary support group, including family circumstances	0.000	0.996	0.004
Z63.7 Other stressful life events affecting family and household	0.000	0.996	0.004
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
K74.0 Hepatic fibrosis	0.000	0.996	0.004
H83.1 Labyrinthine fistula	0.004	0.996	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.996	0.004
D52.9 Folate deficiency anaemia, unspecified	0.000	0.996	0.004
H83.3 Noise effects on inner ear	0.004	0.996	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.996	0.004
S02.61 Fracture of mandible (open)	0.004	0.996	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.996	0.004
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.996	0.004
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.996	0.004
H83.2 Labyrinthine dysfunction	0.003	0.996	0.000
F40.1 Social phobias	0.000	0.996	0.003
H83.9 Disease of inner ear, unspecified	0.003	0.996	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.996	0.003
N42.9 Disorder of prostate, unspecified	0.000	0.996	0.004
R49 Voice disturbances	0.003	0.997	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.997	0.003
F40.0 Agoraphobia	0.000	0.997	0.003
J93.1 Other spontaneous pneumothorax	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.000	0.997	0.003
F40.9 Phobic anxiety disorder, unspecified	0.000	0.997	0.003
K74.4 Secondary biliary cirrhosis	0.000	0.997	0.003
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.997	0.003
Z63.9 Problem related to primary support group, unspecified	0.000	0.997	0.003
Z63.3 Absence of family member	0.000	0.997	0.003
Z63.2 Inadequate family support	0.000	0.997	0.003
Z63.1 Problems in relationship with parents and in-laws	0.000	0.997	0.003
M65.8 Other synovitis and tenosynovitis	0.000	0.997	0.003
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.997	0.003
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.997	0.003
M25.74 Osteophyte (Hand)	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
F40.8 Other phobic anxiety disorders	0.000	0.997	0.003
Q24.8 Other specified congenital malformations of heart	0.000	0.997	0.003
M65 Synovitis and tenosynovitis	0.000	0.997	0.003
Z63.6 Dependent relative needing care at home	0.000	0.997	0.003
Z63.4 Disappearance and death of family member	0.000	0.997	0.003
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.997	0.003
H93.1 Tinnitus	0.003	0.997	0.000
H81 Disorders of vestibular function	0.003	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.997	0.003
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.997	0.003
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.997	0.003
R49.1 Aphonia	0.003	0.997	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.003	0.997	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.997	0.003
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.997	0.003
K59.1 Functional diarrhoea	0.000	0.997	0.003
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.997	0.003
H81.3 Other peripheral vertigo	0.003	0.997	0.000
M65.1 Other infective (teno)synovitis	0.000	0.997	0.003
H81.8 Other disorders of vestibular function	0.003	0.997	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.997	0.003
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
J93.8 Other pneumothorax	0.003	0.997	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.997	0.003
D48.5 Skin	0.003	0.997	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.997	0.003
R49.2 Hypernasality and hyponasality	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
F19.1 Harmful use	0.000	0.997	0.003
M65.14 Other infective (teno)synovitis (Hand)	0.000	0.997	0.003
N80.1 Endometriosis of ovary	0.000	0.997	0.003
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.997	0.003
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.997	0.003
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.997	0.003
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.997	0.003
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.997	0.003
J93 Pneumothorax	0.003	0.997	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
T91.3 Sequelae of injury of spinal cord	0.000	0.997	0.003
Z80.6 Family history of leukaemia	0.000	0.997	0.003
M65.2 Calcific tendinitis	0.000	0.997	0.002
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.997	0.002
G82.1 Spastic paraplegia	0.000	0.997	0.003
D07.1 Vulva	0.003	0.997	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.000	0.998	0.002
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.000	0.998	0.002
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.000	0.998	0.002
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.000	0.998	0.002
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.000	0.998	0.002
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.000	0.998	0.002
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.000	0.998	0.002
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.000	0.998	0.002
M65.0 Abscess of tendon sheath	0.000	0.998	0.002
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.998	0.002
R49.8 Other and unspecified voice disturbances	0.002	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
M65.19 Other infective (teno)synovitis (Site unspecified)	0.000	0.998	0.002
M65.18 Other infective (teno)synovitis (Other)	0.000	0.998	0.002
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.000	0.998	0.002
M65.16 Other infective (teno)synovitis (Lower leg)	0.000	0.998	0.002
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.000	0.998	0.002
M65.13 Other infective (teno)synovitis (Forearm)	0.000	0.998	0.002
M65.12 Other infective (teno)synovitis (Upper arm)	0.000	0.998	0.002
M65.11 Other infective (teno)synovitis (Shoulder region)	0.000	0.998	0.002
M65.10 Other infective (teno)synovitis (Multiple sites)	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.002
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
R57.2 Septic shock	0.002	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.998	0.002
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
M65.29 Calcific tendinitis (Site unspecified)	0.000	0.998	0.002
M65.28 Calcific tendinitis (Other)	0.000	0.998	0.002
M65.27 Calcific tendinitis (Ankle and foot)	0.000	0.998	0.002
M65.26 Calcific tendinitis (Lower leg)	0.000	0.998	0.002
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.000	0.998	0.002
M65.24 Calcific tendinitis (Hand)	0.000	0.998	0.002
M65.23 Calcific tendinitis (Forearm)	0.000	0.998	0.002
M65.22 Calcific tendinitis (Upper arm)	0.000	0.998	0.002
M65.20 Calcific tendinitis (Multiple sites)	0.000	0.998	0.002
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
H61 Other disorders of external ear	0.000	0.998	0.002
M65.09 Abscess of tendon sheath (Site unspecified)	0.000	0.998	0.002
M65.08 Abscess of tendon sheath (Other)	0.000	0.998	0.002
M65.07 Abscess of tendon sheath (Ankle and foot)	0.000	0.998	0.002
M65.06 Abscess of tendon sheath (Lower leg)	0.000	0.998	0.002
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.000	0.998	0.002
M65.03 Abscess of tendon sheath (Forearm)	0.000	0.998	0.002
M65.02 Abscess of tendon sheath (Upper arm)	0.000	0.998	0.002
M65.01 Abscess of tendon sheath (Shoulder region)	0.000	0.998	0.002
M65.00 Abscess of tendon sheath (Multiple sites)	0.000	0.998	0.002
M65.21 Calcific tendinitis (Shoulder region)	0.000	0.998	0.002
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
D07.2 Vagina	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.998	0.002
Z35.6 Supervision of very young primigravida	0.000	0.998	0.002
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.998	0.002
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
D52 Folate deficiency anaemia	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.998	0.002
D07 Carcinoma in situ of other and unspecified genital organs	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
C10.9 Oropharynx, unspecified	0.002	0.998	0.000
M65.04 Abscess of tendon sheath (Hand)	0.000	0.998	0.002
D07.5 Prostate	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
Q24.0 Dextrocardia	0.000	0.998	0.002
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
N39.9 Disorder of urinary system, unspecified	0.002	0.998	0.000
D07.0 Endometrium	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.998	0.002
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
K59.8 Other specified functional intestinal disorders	0.000	0.998	0.002
Q24.6 Congenital heart block	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.000	0.998	0.002
D52.8 Other folate deficiency anaemias	0.000	0.998	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.998	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
D07.6 Other and unspecified male genital organs	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.998	0.002
L92.0 Granuloma annulare	0.002	0.998	0.000
M65.3 Trigger finger	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.001
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.001
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.001
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.001
E80.4 Gilbert's syndrome	0.002	0.998	0.000
J05.1 Acute epiglottitis	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
F99 Mental disorder, not otherwise specified	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
D07.4 Penis	0.001	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
T00.8 Superficial injuries involving other combinations of body regions	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
K59.2 Neurogenic bowel, not elsewhere classified	0.000	0.998	0.002
B01.9 Varicella without complications	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
W05.0 Home	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.000	0.998	0.001
H81.2 Vestibular neuronitis	0.001	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.001
D32.9 Meninges, unspecified	0.000	0.998	0.002
M85.6 Other cyst of bone	0.001	0.998	0.000
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.000	0.998	0.001
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.000	0.998	0.001
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.998	0.000
M65.39 Trigger finger-Site unspec	0.000	0.999	0.001
M65.38 Trigger finger-Other	0.000	0.999	0.001
M65.37 Trigger finger-Ankle/foot	0.000	0.999	0.001
M65.36 Trigger finger-Lower leg	0.000	0.999	0.001
M65.35 Trigger finger-Pelvic/thigh	0.000	0.999	0.001
M65.33 Trigger finger-Forearm	0.000	0.999	0.001
M65.32 Trigger finger-Upper arm	0.000	0.999	0.001
M65.31 Trigger finger-Shldr region	0.000	0.999	0.001
M65.30 Trigger finger-Mult sites	0.000	0.999	0.001
M85.65 Other cyst of bone (Pelvic region and thigh)	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.999	0.001
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
O00.1 Tubal pregnancy	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
T00.9 Multiple superficial injuries, unspecified	0.000	0.999	0.001
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.999	0.001
K27 Peptic ulcer, site unspecified	0.000	0.999	0.001
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.999	0.001
D05.0 Lobular carcinoma in situ	0.000	0.999	0.001
F11.3 Withdrawal state	0.000	0.999	0.001
H01.0 Blepharitis	0.001	0.999	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.999	0.001
R44.3 Hallucinations, unspecified	0.000	0.999	0.001
F11.2 Dependence syndrome	0.000	0.999	0.001
R44.0 Auditory hallucinations	0.000	0.999	0.001
S05.1 Contusion of eyeball and orbital tissues	0.000	0.999	0.001
Y54.5 Other diuretics	0.000	0.999	0.001
Y83.3 Surgical operation with formation of external stoma	0.001	0.999	0.000
Z39.0 Care and examination immediately after delivery	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.000	0.999	0.001
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.000
T00 Superficial injuries involving multiple body regions	0.000	0.999	0.001
S92.70 Multiple fractures of foot (closed)	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.000	0.999	0.001
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.999	0.001
K59 Other functional intestinal disorders	0.000	0.999	0.001
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.999	0.001
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.999	0.001
D35.1 Parathyroid gland	0.001	0.999	0.000
F20.8 Other schizophrenia	0.000	0.999	0.001
H16.4 Corneal neovascularisation	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
F20 Schizophrenia	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M85.69 Other cyst of bone (Site unspecified)	0.001	0.999	0.000
M85.63 Other cyst of bone (Forearm)	0.001	0.999	0.000
M85.62 Other cyst of bone (Upper arm)	0.001	0.999	0.000
M85.61 Other cyst of bone (Shoulder region)	0.001	0.999	0.000
M85.60 Other cyst of bone (Multiple sites)	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.000	0.999	0.001
H81.1 Benign paroxysmal vertigo	0.001	0.999	0.000
K27.4 Chronic or unspecified with haemorrhage	0.000	0.999	0.001
R16.1 Splenomegaly, not elsewhere classified	0.000	0.999	0.001
R73.0 Abnormal glucose tolerance test	0.000	0.999	0.001
F11.1 Harmful use	0.000	0.999	0.001
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.999	0.001
K27.5 Chronic or unspecified with perforation	0.000	0.999	0.001
K27.2 Acute with both haemorrhage and perforation	0.000	0.999	0.001
K27.1 Acute with perforation	0.000	0.999	0.001
K27.0 Acute with haemorrhage	0.000	0.999	0.001
K59.9 Functional intestinal disorder, unspecified	0.000	0.999	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.999	0.001
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.999	0.001
F30.2 Mania with psychotic symptoms	0.000	0.999	0.001
H05.2 Exophthalmic conditions	0.001	0.999	0.000
M66.2 Spontaneous rupture of extensor tendons	0.000	0.999	0.001
Q18.9 Congenital malformation of face and neck, unspecified	0.000	0.999	0.001
Q18.8 Other specified congenital malformations of face and neck	0.000	0.999	0.001
Q18.7 Microcheilia	0.000	0.999	0.001
Q18.6 Macrocheilia	0.000	0.999	0.001
Q18.5 Microstomia	0.000	0.999	0.001
Q18.4 Macrostomia	0.000	0.999	0.001
Q18.3 Webbing of neck	0.000	0.999	0.001
Q18.2 Other branchial cleft malformations	0.000	0.999	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.999	0.001
M76.87 Other enthesopathies of lower limb, excluding foot (Ankle and foot)	0.001	0.999	0.000
M85.68 Other cyst of bone (Other)	0.001	0.999	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.999	0.000
K27.3 Acute without haemorrhage or perforation	0.000	0.999	0.001
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.000	0.999	0.001
T00.0 Superficial injuries involving head with neck	0.000	0.999	0.001
T92.2 Sequelae of fracture at wrist and hand level	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
G93.2 Benign intracranial hypertension	0.000	0.999	0.001
H05.4 Enophthalmos	0.001	0.999	0.000
H81.0 Meniere's disease	0.001	0.999	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.999	0.001
W19.2 School, other institution and public administrative area	0.001	0.999	0.000
G60 Hereditary and idiopathic neuropathy	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.000	0.999	0.001
F20.4 Postschizophrenic depression	0.000	0.999	0.001
F20.3 Undifferentiated schizophrenia	0.000	0.999	0.001
F20.1 Hebephrenic schizophrenia	0.000	0.999	0.001
K59.4 Anal spasm	0.000	0.999	0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.001	0.999	0.000
F30 Manic episode	0.000	0.999	0.001
H16 Keratitis	0.000	0.999	0.001
M76.85 Other enthesopathies of lower limb, excluding foot (Pelvic region and thigh)	0.001	0.999	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.999	0.001
M76.8 Other enthesopathies of lower limb, excluding foot	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
R23.1 Pallor	0.000	0.999	0.001
R65.1 Systemic Inflammatory Response Syndrome of infectious origin with organ failure	0.001	0.999	0.000
F11 Mental and behavioural disorders due to use of opioids	0.000	0.999	0.001
F19.9 Unspecified mental and behavioural disorder	0.000	0.999	0.001
F19.8 Other mental and behavioural disorders	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations