TreeWAS – Variant ID: rs11065979

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	1.000	0.000	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000	0.000
I10 Essential (primary) hypertension	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Z95.2 Presence of prosthetic heart valve	1.000	0.000	0.000
Z95.4 Presence of other heart-valve replacement	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.001	0.999
E10-E14 Diabetes mellitus	0.999	0.001	0.000
Z95.1 Presence of aortocoronary bypass graft	0.998	0.002	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.998	0.002	0.000
C50 Malignant neoplasm of breast	0.000	0.004	0.996
C50.9 Breast, unspecified	0.000	0.005	0.995
E20-E35 Disorders of other endocrine glands	0.994	0.006	0.000
I25.2 Old myocardial infarction	0.994	0.006	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.986	0.014	0.000
I20 Angina pectoris	0.985	0.015	0.000
M06.9 Rheumatoid arthritis, unspecified	0.984	0.016	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.983	0.017	0.000
I20.9 Angina pectoris, unspecified	0.982	0.018	0.000
M06 Other rheumatoid arthritis	0.981	0.019	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.019	0.981
E05.9 Thyrotoxicosis, unspecified	0.981	0.019	0.000
E10.5 With peripheral circulatory complications	0.975	0.025	0.000
C50.8 Overlapping lesion of breast	0.000	0.026	0.974
M05-M14 Inflammatory polyarthropathies	0.973	0.027	0.000
I25.5 Ischaemic cardiomyopathy	0.973	0.027	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.972	0.028	0.000
E10.9 Without complications	0.970	0.030	0.000
E27 Other disorders of adrenal gland	0.967	0.033	0.000
C50.1 Central portion of breast	0.000	0.036	0.964
I12 Hypertensive renal disease	0.963	0.037	0.000
E10.3 With ophthalmic complications	0.959	0.041	0.000
M05 Seropositive rheumatoid arthritis	0.956	0.044	0.000
E06 Thyroiditis	0.956	0.044	0.000
I22 Subsequent myocardial infarction	0.953	0.047	0.000
I74 Arterial embolism and thrombosis	0.953	0.047	0.000
M07 Psoriatic and enteropathic arthropathies	0.949	0.051	0.000
E10.1 With ketoacidosis	0.942	0.058	0.000
C50.0 Nipple and areola	0.000	0.059	0.941
M05.9 Seropositive rheumatoid arthritis, unspecified	0.940	0.060	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.063	0.937
M07.3 Other psoriatic arthropathies	0.932	0.068	0.000
E27.1 Primary adrenocortical insufficiency	0.930	0.070	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.930	0.070	0.000
K90.0 Coeliac disease	0.929	0.071	0.000
I73 Other peripheral vascular diseases	0.928	0.072	0.000
E10.4 With neurological complications	0.927	0.073	0.000
E10.2 With renal complications	0.922	0.078	0.000
I12.0 Hypertensive renal disease with renal failure	0.922	0.078	0.000
M06.4 Inflammatory polyarthropathy	0.921	0.079	0.000
I73.9 Peripheral vascular disease, unspecified	0.917	0.083	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.916	0.084	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.914	0.086	0.000
C77.9 Lymph node, unspecified	0.000	0.089	0.911
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.904	0.096	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.901	0.099	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.102	0.898
E23 Hypofunction and other disorders of pituitary gland	0.897	0.103	0.000
E06.3 Autoimmune thyroiditis	0.897	0.103	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.880	0.120	0.000
E10.0 With coma	0.880	0.120	0.000
E20 Hypoparathyroidism	0.879	0.121	0.000
I23 Certain current complications following acute myocardial infarction	0.873	0.127	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.872	0.128	0.000
Z95.3 Presence of xenogenic heart valve	0.869	0.131	0.000
I74.5 Embolism and thrombosis of iliac artery	0.865	0.135	0.000
E50-E64 Other nutritional deficiencies	0.862	0.138	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.853	0.147	0.000
E27.8 Other specified disorders of adrenal gland	0.853	0.147	0.000
I15 Secondary hypertension	0.844	0.156	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.819	0.181	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.814	0.186	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.812	0.188	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.191	0.809
E28 Ovarian dysfunction	0.809	0.191	0.000
C50-C50 Malignant neoplasm of breast	0.000	0.193	0.807
E27.2 Addisonian crisis	0.806	0.194	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.803	0.197	0.000
E23.6 Other disorders of pituitary gland	0.798	0.202	0.000
E22 Hyperfunction of pituitary gland	0.794	0.206	0.000
I05-I09 Chronic rheumatic heart diseases	0.793	0.207	0.000
I25.4 Coronary artery aneurysm	0.793	0.207	0.000
I12.9 Hypertensive renal disease without renal failure	0.792	0.208	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.792	0.208	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.791	0.209	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.791	0.209	0.000
I13 Hypertensive heart and renal disease	0.789	0.211	0.000
I77 Other disorders of arteries and arterioles	0.787	0.213	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.785	0.215	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.785	0.215	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.784	0.216	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.783	0.217	0.000
M05.1 Rheumatoid lung disease	0.782	0.218	0.000
I23.8 Other current complications following acute myocardial infarction	0.781	0.219	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.219	0.781
C78.7 Secondary malignant neoplasm of liver	0.000	0.220	0.780
E06.9 Thyroiditis, unspecified	0.778	0.222	0.000
E03.8 Other specified hypothyroidism	0.775	0.225	0.000
M08 Juvenile arthritis	0.775	0.225	0.000
E20.9 Hypoparathyroidism, unspecified	0.771	0.229	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.770	0.230	0.000
E61 Deficiency of other nutrient elements	0.767	0.233	0.000
E34 Other endocrine disorders	0.762	0.238	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.762	0.238	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.761	0.239	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.246	0.754
M06.98 Rheumatoid arthritis, unspecified (Other)	0.753	0.247	0.000
E23.0 Hypopituitarism	0.753	0.247	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.749	0.251	0.000
E03.1 Congenital hypothyroidism without goitre	0.749	0.251	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.748	0.252	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.253	0.747
I21.4 Acute subendocardial myocardial infarction	0.745	0.255	0.000
I20.8 Other forms of angina pectoris	0.743	0.257	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.258	0.742
D63.8 Anaemia in other chronic diseases classified elsewhere	0.742	0.258	0.000
I25.3 Aneurysm of heart	0.741	0.259	0.000
I25.6 Silent myocardial ischaemia	0.740	0.260	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.740	0.260	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.261	0.739
M05.0 Felty's syndrome	0.735	0.265	0.000
E06.1 Subacute thyroiditis	0.733	0.267	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.732	0.268	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.731	0.269	0.000
D55-D59 Haemolytic anaemias	0.730	0.270	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.271	0.729
D75 Other diseases of blood and blood-forming organs	0.729	0.271	0.000
E31 Polyglandular dysfunction	0.729	0.271	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.727	0.272	0.000
D60-D64 Aplastic and other anaemias	0.727	0.273	0.000
E07 Other disorders of thyroid	0.725	0.275	0.000
E23.2 Diabetes insipidus	0.725	0.275	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.724	0.276	0.000
E10.8 With unspecified complications	0.723	0.277	0.000
D75.1 Secondary polycythaemia	0.721	0.279	0.000
E25 Adrenogenital disorders	0.720	0.280	0.000
M06.8 Other specified rheumatoid arthritis	0.719	0.281	0.000
M11 Other crystal arthropathies	0.717	0.282	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.716	0.284	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.715	0.285	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.713	0.287	0.000
E58 Dietary calcium deficiency	0.713	0.287	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.713	0.287	0.000
E32 Diseases of thymus	0.713	0.287	0.000
E30 Disorders of puberty, not elsewhere classified	0.713	0.287	0.000
E22.1 Hyperprolactinaemia	0.710	0.290	0.000
M12 Other specific arthropathies	0.708	0.292	0.000
E05.5 Thyroid crisis or storm	0.707	0.293	0.000
E05.4 Thyrotoxicosis factitia	0.707	0.293	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.707	0.293	0.000
E28.3 Primary ovarian failure	0.705	0.295	0.000
I15.1 Hypertension secondary to other renal disorders	0.705	0.295	0.000
M06.2 Rheumatoid bursitis	0.703	0.296	0.000
M06.1 Adult-onset Still's disease	0.703	0.296	0.000
I05 Rheumatic mitral valve diseases	0.704	0.296	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.703	0.297	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.298	0.702
E61.1 Iron deficiency	0.700	0.300	0.000
I77.6 Arteritis, unspecified	0.699	0.301	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.698	0.302	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.698	0.302	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.697	0.303	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.695	0.305	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.306	0.694
M07.36 Other psoriatic arthropathies (Lower leg)	0.694	0.306	0.000
E27.5 Adrenomedullary hyperfunction	0.693	0.307	0.000
E27.0 Other adrenocortical overactivity	0.693	0.307	0.000
# Top node	0.693	0.307	0.000
M06.0 Seronegative rheumatoid arthritis	0.692	0.308	0.000
E20.1 Pseudohypoparathyroidism	0.689	0.311	0.000
D59 Acquired haemolytic anaemia	0.688	0.312	0.000
E06.5 Other chronic thyroiditis	0.686	0.314	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.686	0.314	0.000
E06.4 Drug-induced thyroiditis	0.685	0.315	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.685	0.315	0.000
E06.0 Acute thyroiditis	0.685	0.315	0.000
E10.6 With other specified complications	0.683	0.317	0.000
I22.8 Subsequent myocardial infarction of other sites	0.683	0.317	0.000
D75.2 Essential thrombocytosis	0.683	0.317	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.681	0.319	0.000
M07.5 Arthropathy in ulcerative colitis	0.680	0.319	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.680	0.319	0.000
M07.2 Psoriatic spondylitis	0.680	0.319	0.000
M07.1 Arthritis mutilans	0.680	0.319	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.680	0.319	0.000
M07.6 Other enteropathic arthropathies	0.676	0.323	0.000
K90 Intestinal malabsorption	0.676	0.324	0.000
E26 Hyperaldosteronism	0.675	0.325	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.674	0.326	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.674	0.326	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.673	0.327	0.000
Chapter II Neoplasms	0.000	0.329	0.671
M05.8 Other seropositive rheumatoid arthritis	0.669	0.331	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.668	0.331	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.668	0.331	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.667	0.333	0.000
I77.1 Stricture of artery	0.666	0.334	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.337	0.663
D56 Thalassaemia	0.662	0.338	0.000
M10 Gout	0.661	0.339	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.660	0.340	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.660	0.340	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.660	0.340	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.660	0.340	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.660	0.340	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.660	0.340	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.660	0.340	0.000
M07.38 Other psoriatic arthropathies (Other)	0.660	0.340	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.657	0.342	0.000
E10.7 With multiple complications	0.655	0.345	0.000
I21.9 Acute myocardial infarction, unspecified	0.653	0.347	0.000
I15.0 Renovascular hypertension	0.652	0.348	0.000
I73.8 Other specified peripheral vascular diseases	0.652	0.348	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.651	0.349	0.000
E27.9 Disorder of adrenal gland, unspecified	0.648	0.352	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.643	0.357	0.000
E23.1 Drug-induced hypopituitarism	0.643	0.357	0.000
I26 Pulmonary embolism	0.643	0.357	0.000
C76.0 Head, face and neck	0.000	0.359	0.641
C78.2 Secondary malignant neoplasm of pleura	0.000	0.359	0.641
I13.1 Hypertensive heart and renal disease with renal failure	0.640	0.360	0.000
D59.1 Other autoimmune haemolytic anaemias	0.640	0.360	0.000
I05.2 Mitral stenosis with insufficiency	0.638	0.362	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.638	0.362	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.635	0.365	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.633	0.367	0.000
E16 Other disorders of pancreatic internal secretion	0.631	0.369	0.000
E20.8 Other hypoparathyroidism	0.630	0.370	0.000
E20.0 Idiopathic hypoparathyroidism	0.630	0.370	0.000
I00-I02 Acute rheumatic fever	0.629	0.371	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.627	0.373	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.626	0.374	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.626	0.374	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.626	0.374	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.626	0.374	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.626	0.374	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.626	0.374	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.626	0.374	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.625	0.375	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.625	0.375	0.000
M06.3 Rheumatoid nodule	0.625	0.375	0.000
I07 Rheumatic tricuspid valve diseases	0.624	0.376	0.000
E51 Thiamine deficiency	0.621	0.379	0.000
E07.9 Disorder of thyroid, unspecified	0.621	0.379	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.382	0.618
E64 Sequelae of malnutrition and other nutritional deficiencies	0.618	0.382	0.000
E63 Other nutritional deficiencies	0.618	0.382	0.000
E50 Vitamin A deficiency	0.618	0.382	0.000
E60 Dietary zinc deficiency	0.618	0.382	0.000
E59 Dietary selenium deficiency	0.618	0.382	0.000
E54 Ascorbic acid deficiency	0.618	0.382	0.000
E52 Niacin deficiency [pellagra]	0.618	0.382	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.618	0.382	0.000
I05.0 Mitral stenosis	0.616	0.384	0.000
I15.9 Seconday hypertension, unspecified	0.615	0.385	0.000
I70 Atherosclerosis	0.615	0.385	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.614	0.386	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.613	0.387	0.000
I20.1 Angina pectoris with documented spasm	0.613	0.387	0.000
D58 Other hereditary haemolytic anaemias	0.612	0.388	0.000
K70-K77 Diseases of liver	0.611	0.389	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.610	0.390	0.000
K74 Fibrosis and cirrhosis of liver	0.610	0.390	0.000
K90-K93 Other diseases of the digestive system	0.610	0.390	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.392	0.608
E13 Other specified diabetes mellitus	0.607	0.393	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.606	0.394	0.000
Chapter XI Diseases of the digestive system	0.606	0.394	0.000
I15.8 Other secondary hypertension	0.605	0.395	0.000
E40-E46 Malnutrition	0.605	0.395	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.395	0.605
D56.3 Thalassaemia trait	0.604	0.396	0.000
I77.2 Rupture of artery	0.603	0.397	0.000
M08.0 Juvenile rheumatoid arthritis	0.599	0.401	0.000
M08.9 Juvenile arthritis, unspecified	0.597	0.403	0.000
I06 Rheumatic aortic valve diseases	0.595	0.404	0.000
I15.2 Hypertension secondary to endocrine disorders	0.595	0.405	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.595	0.405	0.000
M05.2 Rheumatoid vasculitis	0.593	0.407	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.407	0.593
K73 Chronic hepatitis, not elsewhere classified	0.591	0.409	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.590	0.409	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.590	0.410	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.589	0.411	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.588	0.412	0.000
E53 Deficiency of other B group vitamins	0.588	0.412	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.413	0.587
E29 Testicular dysfunction	0.586	0.414	0.000
K74.3 Primary biliary cirrhosis	0.586	0.414	0.000
E56 Other vitamin deficiencies	0.585	0.415	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.585	0.415	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.581	0.419	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.580	0.420	0.000
E28.9 Ovarian dysfunction, unspecified	0.580	0.420	0.000
E28.8 Other ovarian dysfunction	0.580	0.420	0.000
E28.1 Androgen excess	0.580	0.420	0.000
E28.0 Oestrogen excess	0.580	0.420	0.000
M05.09 Felty's syndrome (Site unspecified)	0.577	0.423	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.576	0.424	0.000
I28 Other diseases of pulmonary vessels	0.575	0.425	0.000
E34.0 Carcinoid syndrome	0.574	0.426	0.000
K74.0 Hepatic fibrosis	0.573	0.427	0.000
I99 Other and unspecified disorders of circulatory system	0.572	0.428	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.430	0.570
E05.8 Other thyrotoxicosis	0.569	0.430	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.569	0.430	0.000
E22.8 Other hyperfunction of pituitary gland	0.569	0.430	0.000
D73 Diseases of spleen	0.567	0.433	0.000
K75 Other inflammatory liver diseases	0.566	0.434	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.565	0.434	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.565	0.434	0.000
I77.5 Necrosis of artery	0.564	0.436	0.000
I77.4 Coeliac artery compression syndrome	0.564	0.436	0.000
I77.3 Arterial fibromuscular dysplasia	0.564	0.436	0.000
E21.3 Hyperparathyroidism, unspecified	0.563	0.437	0.000
I86 Varicose veins of other sites	0.563	0.437	0.000
E34.3 Short stature, not elsewhere classified	0.563	0.437	0.000
E15 Nondiabetic hypoglycaemic coma	0.563	0.437	0.000
C80 Malignant neoplasm without specification of site	0.000	0.438	0.562
E34.8 Other specified endocrine disorders	0.562	0.438	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.562	0.438	0.000
M05.18 Rheumatoid lung disease (Other)	0.561	0.439	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.561	0.439	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.561	0.439	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.561	0.439	0.000
M05.14 Rheumatoid lung disease (Hand)	0.561	0.439	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.561	0.439	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.561	0.439	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.561	0.439	0.000
C50.6 Axillary tail of breast	0.000	0.439	0.560
I13.9 Hypertensive heart and renal disease, unspecified	0.561	0.439	0.000
E16.2 Hypoglycaemia, unspecified	0.560	0.440	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.558	0.442	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.442	0.558
M08.8 Other juvenile arthritis	0.555	0.444	0.000
M08.4 Pauciarticular juvenile arthritis	0.555	0.444	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.555	0.444	0.000
M08.2 Juvenile arthritis with systemic onset	0.555	0.444	0.000
M08.1 Juvenile ankylosing spondylitis	0.555	0.444	0.000
K74.5 Biliary cirrhosis, unspecified	0.555	0.445	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.555	0.445	0.000
I81 Portal vein thrombosis	0.555	0.445	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.552	0.448	0.000
M11.2 Other chondrocalcinosis	0.551	0.448	0.000
E61.9 Deficiency of nutrient element, unspecified	0.550	0.450	0.000
E61.8 Deficiency of other specified nutrient elements	0.550	0.450	0.000
E61.7 Deficiency of multiple nutrient elements	0.550	0.450	0.000
E61.6 Vanadium deficiency	0.550	0.450	0.000
E61.5 Molybdenum deficiency	0.550	0.450	0.000
E61.4 Chromium deficiency	0.550	0.450	0.000
E61.3 Manganese deficiency	0.550	0.450	0.000
E61.0 Copper deficiency	0.550	0.450	0.000
I86.4 Gastric varices	0.550	0.450	0.000
E61.2 Magnesium deficiency	0.548	0.452	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.453	0.547
E34.5 Androgen resistance syndrome	0.547	0.453	0.000
E34.4 Constitutional tall stature	0.547	0.453	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.547	0.453	0.000
E34.1 Other hypersecretion of intestinal hormones	0.547	0.453	0.000
I77.0 Arteriovenous fistula, acquired	0.545	0.454	0.000
M12.2 Villonodular synovitis (pigmented)	0.544	0.456	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.542	0.458	0.000
M10.0 Idiopathic gout	0.541	0.459	0.000
E34.9 Endocrine disorder, unspecified	0.541	0.459	0.000
E31.0 Autoimmune polyglandular failure	0.539	0.461	0.000
D57 Sickle-cell disorders	0.537	0.463	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.536	0.464	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.464	0.536
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.464	0.535
C76.7 Other ill-defined sites	0.000	0.464	0.535
C76.5 Lower limb	0.000	0.464	0.535
C76.4 Upper limb	0.000	0.464	0.535
C76.1 Thorax	0.000	0.466	0.534
C76.3 Pelvis	0.000	0.466	0.533
C76.2 Abdomen	0.000	0.467	0.533
M05.08 Felty's syndrome (Other)	0.527	0.473	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.527	0.473	0.000
M05.06 Felty's syndrome (Lower leg)	0.527	0.473	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.527	0.473	0.000
M05.04 Felty's syndrome (Hand)	0.527	0.473	0.000
M05.03 Felty's syndrome (Forearm)	0.527	0.473	0.000
M05.02 Felty's syndrome (Upper arm)	0.527	0.473	0.000
M05.01 Felty's syndrome (Shoulder region)	0.527	0.473	0.000
M05.00 Felty's syndrome (Multiple sites)	0.527	0.473	0.000
E55 Vitamin D deficiency	0.527	0.473	0.000
K75.4 Autoimmune hepatitis	0.527	0.473	0.000
M14 Arthropathies in other diseases classified elsewhere	0.525	0.474	0.001
C77.2 Intra-abdominal lymph nodes	0.000	0.475	0.525
D59.0 Drug-induced autoimmune haemolytic anaemia	0.525	0.475	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.524	0.476	0.000
D55 Anaemia due to enzyme disorders	0.524	0.476	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.523	0.476	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.523	0.477	0.000
E31.9 Polyglandular dysfunction, unspecified	0.522	0.477	0.000
E31.8 Other polyglandular dysfunction	0.522	0.477	0.000
E31.1 Polyglandular hyperfunction	0.522	0.477	0.000
M11.9 Crystal arthropathy, unspecified	0.521	0.479	0.000
E07.1 Dyshormogenetic goitre	0.520	0.480	0.000
E07.0 Hypersecretion of calcitonin	0.520	0.480	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.520	0.480	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.520	0.480	0.000
D74 Methaemoglobinaemia	0.519	0.481	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.519	0.481	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.519	0.481	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.482	0.518
M12.5 Traumatic arthropathy	0.518	0.482	0.000
I05.8 Other mitral valve diseases	0.517	0.482	0.000
E25.9 Adrenogenital disorder, unspecified	0.516	0.484	0.000
E25.8 Other adrenogenital disorders	0.516	0.484	0.000
I78 Diseases of capillaries	0.516	0.484	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.515	0.484	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.515	0.484	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.515	0.484	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.515	0.484	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.515	0.484	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.515	0.484	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.515	0.484	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.515	0.484	0.000
C45 Mesothelioma	0.000	0.485	0.515
D58.9 Hereditary haemolytic anaemia, unspecified	0.515	0.485	0.000
M11.1 Familial chondrocalcinosis	0.514	0.485	0.000
M11.0 Hydroxyapatite deposition disease	0.514	0.485	0.000
E28.2 Polycystic ovarian syndrome	0.514	0.485	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.513	0.486	0.000
E12.8 With unspecified complications	0.513	0.486	0.000
E12.7 With multiple complications	0.513	0.486	0.000
E12.6 With other specified complications	0.513	0.486	0.000
E12.5 With peripheral circulatory complications	0.513	0.486	0.000
E12.4 With neurological complications	0.513	0.486	0.000
E12.3 With ophthalmic complications	0.513	0.486	0.000
E12.2 With renal complications	0.513	0.486	0.000
E12.1 With ketoacidosis	0.513	0.486	0.000
E12.0 With coma	0.513	0.486	0.000
M00-M03 Infectious arthropathies	0.513	0.487	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.488	0.512
K73.9 Chronic hepatitis, unspecified	0.512	0.488	0.000
E30.9 Disorder of puberty, unspecified	0.511	0.489	0.000
E30.8 Other disorders of puberty	0.511	0.489	0.000
E30.1 Precocious puberty	0.511	0.489	0.000
E30.0 Delayed puberty	0.511	0.489	0.000
E32.9 Disease of thymus, unspecified	0.511	0.489	0.000
E32.8 Other diseases of thymus	0.511	0.489	0.000
E32.1 Abscess of thymus	0.511	0.489	0.000
E32.0 Persistent hyperplasia of thymus	0.511	0.489	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.511	0.489	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.511	0.489	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.511	0.489	0.000
I74.8 Embolism and thrombosis of other arteries	0.511	0.489	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.511	0.489	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.492	0.508
M12.4 Intermittent hydrarthrosis	0.507	0.493	0.000
M12.1 Kaschin-Beck disease	0.507	0.493	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.507	0.493	0.000
E21.2 Other hyperparathyroidism	0.507	0.493	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.494	0.506
D56.1 Beta thalassaemia	0.505	0.495	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.504	0.495	0.000
M06.18 Adult-onset Still's disease (Other)	0.504	0.495	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.504	0.495	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.504	0.495	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.504	0.495	0.000
M06.14 Adult-onset Still's disease (Hand)	0.504	0.495	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.504	0.495	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.504	0.495	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.504	0.495	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.504	0.495	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.504	0.495	0.000
M06.28 Rheumatoid bursitis (Other)	0.504	0.495	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.504	0.495	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.504	0.495	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.504	0.495	0.000
M06.24 Rheumatoid bursitis (Hand)	0.504	0.495	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations