TreeWAS – Variant ID: rs11079764

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R52.1 Chronic intractable pain	0.043	0.957	0.000
S01.1 Open wound of eyelid and periocular area	0.042	0.958	0.000
S01 Open wound of head	0.033	0.967	0.000
S01.5 Open wound of lip and oral cavity	0.030	0.970	0.000
S01.9 Open wound of head, part unspecified	0.030	0.970	0.000
N39.8 Other specified disorders of urinary system	0.029	0.971	0.000
S01.8 Open wound of other parts of head	0.028	0.972	0.000
S01.7 Multiple open wounds of head	0.025	0.975	0.000
S01.2 Open wound of nose	0.024	0.976	0.000
S01.3 Open wound of ear	0.022	0.978	0.000
S01.4 Open wound of cheek and temporomandibular area	0.020	0.979	0.000
K92.0 Haematemesis	0.016	0.984	0.000
J32.9 Chronic sinusitis, unspecified	0.012	0.988	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.011	0.989	0.000
J32 Chronic sinusitis	0.011	0.989	0.000
J32.2 Chronic ethmoidal sinusitis	0.010	0.990	0.000
J32.0 Chronic maxillary sinusitis	0.009	0.991	0.000
J32.4 Chronic pansinusitis	0.009	0.991	0.000
J32.3 Chronic sphenoidal sinusitis	0.009	0.991	0.000
J32.1 Chronic frontal sinusitis	0.008	0.992	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.008	0.992	0.000
Y43.4 Immunosuppressive agents	0.006	0.994	0.000
J32.8 Other chronic sinusitis	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
S01.0 Open wound of scalp	0.006	0.994	0.000
R52 Pain, not elsewhere classified	0.005	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
M25.46 Effusion of joint (Lower leg)	0.005	0.995	0.000
K82.8 Other specified diseases of gallbladder	0.005	0.995	0.000
Y43.3 Other antineoplastic drugs	0.005	0.995	0.000
R52.0 Acute pain	0.004	0.996	0.000
Z89.4 Acquired absence of foot and ankle	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
Y43 Primarily systemic agents	0.004	0.996	0.000
K82.1 Hydrops of gallbladder	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.996	0.004
I63.8 Other cerebral infarction	0.004	0.996	0.000
Y43.1 Antineoplastic antimetabolites	0.004	0.996	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.004	0.996	0.000
M88.9 Paget's disease of bone, unspecified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
H49.0 Third [oculomotor] nerve palsy	0.004	0.996	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.004	0.996	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M25.47 Effusion of joint (Ankle and foot)	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
M25.4 Effusion of joint	0.003	0.997	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.997	0.003
T40.1 Heroin	0.003	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.997	0.003
Q89.2 Congenital malformations of other endocrine glands	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
H49 Paralytic strabismus	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
I63 Cerebral infarction	0.003	0.997	0.000
M18 Arthrosis of first carpometacarpal joint	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
H49.9 Paralytic strabismus, unspecified	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.003	0.997	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.003	0.997	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.003	0.997	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.003	0.997	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.003	0.997	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Z72.2 Drug use	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
C21.0 Anus, unspecified	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
H49.8 Other paralytic strabismus	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
K82 Other diseases of gallbladder	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
Z45.1 Adjustment and management of infusion pump	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
N43.3 Hydrocele, unspecified	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
M88.8 Paget's disease of other bones	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
R16.1 Splenomegaly, not elsewhere classified	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
M25.43 Effusion of joint (Forearm)	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
M88 Paget's disease of bone [osteitis deformans]	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.003	0.997	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.997	0.000
M25.48 Effusion of joint (Other)	0.002	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
K82.0 Obstruction of gallbladder	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.997	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.997	0.000
M51 Other intervertebral disk disorders	0.000	0.997	0.003
M25.40 Effusion of joint (Multiple sites)	0.002	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.997	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
M88.88 Paget's disease of other bones (Other)	0.002	0.998	0.000
C21.1 Anal canal	0.000	0.998	0.002
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
M88.0 Paget's disease of skull	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
M51.9 Intervertebral disk disorder, unspecified	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
K82.9 Disease of gallbladder, unspecified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.002	0.998	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.002	0.998	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.002	0.998	0.000
M88.84 Paget's disease of other bones (Hand)	0.002	0.998	0.000
M88.83 Paget's disease of other bones (Forearm)	0.002	0.998	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.002	0.998	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.002	0.998	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
M88.00 Paget's disease of skull-Mult sites	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
K82.3 Fistula of gallbladder	0.002	0.998	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.002	0.998	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.000	0.998	0.002
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
G57.5 Tarsal tunnel syndrome	0.000	0.998	0.002
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M51.3 Other specified intervertebral disk degeneration	0.000	0.998	0.002
M51.4 Schmorl's nodes	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
M19.94 Arthrosis, unspecified (Hand)	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
T36.4 Tetracyclines	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
M88.09 Paget's disease of skull-Site unspec	0.002	0.998	0.000
M88.08 Paget's disease of skull-Other	0.002	0.998	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.002	0.998	0.000
M88.06 Paget's disease of skull-Lower Leg	0.002	0.998	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.002	0.998	0.000
M88.04 Paget's disease of skull-Hand	0.002	0.998	0.000
M88.03 Paget's disease of skull-Forearm	0.002	0.998	0.000
M88.02 Paget's disease of skull-Upper arm	0.002	0.998	0.000
M88.01 Paget's disease of skull-Shldr region	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.998	0.002
Z60.2 Living alone	0.000	0.998	0.002
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.998	0.002
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.998	0.002
T47.4 Other laxatives	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.001	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.000	0.998	0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
R52.2 Other chronic pain	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
G55.0 Nerve root and plexus compressions in neoplastic disease	0.002	0.998	0.000
K82.2 Perforation of gallbladder	0.002	0.998	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.998	0.001
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
C41.1 Mandible	0.002	0.998	0.000
C41.2 Vertebral column	0.002	0.998	0.000
H01.9 Inflammation of eyelid, unspecified	0.002	0.998	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.002	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.998	0.001
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.998	0.001
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.998	0.001
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.998	0.001
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.998	0.001
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.998	0.001
T21.7 Corrosion of third degree of trunk	0.001	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
Q89.3 Situs inversus	0.000	0.998	0.001
F60 Specific personality disorders	0.002	0.998	0.000
O47.9 False labour, unspecified	0.000	0.998	0.002
T21.2 Burn of second degree of trunk	0.001	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.998	0.001
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.000	0.998	0.001
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.000	0.998	0.001
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.000	0.998	0.001
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.000	0.998	0.001
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.000	0.998	0.001
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.000	0.998	0.001
F60.0 Paranoid personality disorder	0.001	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
R68.3 Clubbing of fingers	0.001	0.998	0.000
M87 Osteonecrosis	0.000	0.998	0.001
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.998	0.001
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
Y84.6 Urinary catheterisation	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.001
F60.9 Personality disorder, unspecified	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.000	0.998	0.001
Q89.8 Other specified congenital malformations	0.000	0.998	0.001
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.998	0.001
Q89.4 Conjoined twins	0.000	0.998	0.001
Q89.1 Congenital malformations of adrenal gland	0.000	0.998	0.001
Q89.0 Congenital malformations of spleen	0.000	0.998	0.001
R68.2 Dry mouth, unspecified	0.001	0.998	0.000
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.000	0.998	0.001
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.998	0.001
T21.1 Burn of first degree of trunk	0.001	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.001	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
R68 Other general symptoms and signs	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
M87.8 Other osteonecrosis	0.000	0.999	0.001
F60.8 Other specific personality disorders	0.001	0.999	0.000
H65.3 Chronic mucoid otitis media	0.001	0.999	0.000
R73.0 Abnormal glucose tolerance test	0.001	0.999	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
K12.3 Oral mucositis (ulcerative)	0.001	0.999	0.000
K25.3 Acute without haemorrhage or perforation	0.000	0.999	0.001
S61.8 Open wound of other parts of wrist and hand	0.001	0.999	0.000
Z89.6 Acquired absence of leg above knee	0.001	0.999	0.000
Z92.8 Personal history of other medical treatment	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.999	0.001
F60.4 Histrionic personality disorder	0.001	0.999	0.000
B02.9 Zoster without complication	0.001	0.999	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.999	0.001
H11.4 Other conjunctival vascular disorders and cysts	0.001	0.999	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.999	0.001
C41.0 Bones of skull and face	0.001	0.999	0.000
M87.3 Other secondary osteonecrosis	0.000	0.999	0.001
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.999	0.001
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.999	0.001
O21.9 Vomiting of pregnancy, unspecified	0.001	0.999	0.000
T39.1 4-Aminophenol derivatives	0.001	0.999	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.001	0.999	0.000
F60.2 Dissocial personality disorder	0.001	0.999	0.000
M87.1 Osteonecrosis due to drugs	0.000	0.999	0.001
R68.1 Nonspecific symptoms peculiar to infancy	0.001	0.999	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.999	0.001
Y40.8 Other systemic antibiotics	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.001	0.999	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.001	0.999	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.001	0.999	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.999	0.001
M87.88 Other osteonecrosis (Other)	0.000	0.999	0.001
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.999	0.001
M87.86 Other osteonecrosis (Lower leg)	0.000	0.999	0.001
M87.84 Other osteonecrosis (Hand)	0.000	0.999	0.001
M87.83 Other osteonecrosis (Forearm)	0.000	0.999	0.001
M87.82 Other osteonecrosis (Upper arm)	0.000	0.999	0.001
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.999	0.001
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.999	0.001
C74.0 Cortex of adrenal gland	0.000	0.999	0.001
S80.0 Contusion of knee	0.000	0.999	0.001
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
L27 Dermatitis due to substances taken internally	0.001	0.999	0.000
C41.8 Overlapping lesion of bone and articular cartilage	0.001	0.999	0.000
C41.3 Ribs, sternum and clavicle	0.001	0.999	0.000
H91.8 Other specified hearing loss	0.001	0.999	0.000
Y40.0 Penicillins	0.001	0.999	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.999	0.001
D35.0 Adrenal gland	0.000	0.999	0.001
R68.8 Other specified general symptoms and signs	0.001	0.999	0.000
Z04.1 Examination and observation following transport accident	0.000	0.999	0.001
C44.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
C74.9 Adrenal gland, unspecified	0.000	0.999	0.001
F60.5 Anankastic personality disorder	0.001	0.999	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.000	0.999	0.001
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.000	0.999	0.001
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.000	0.999	0.001
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.000	0.999	0.001
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.000	0.999	0.001
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.000	0.999	0.001
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.000	0.999	0.001
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.000	0.999	0.001
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.000	0.999	0.001
M87.39 Other secondary osteonecrosis (Site unspecified)	0.000	0.999	0.001
M87.38 Other secondary osteonecrosis (Other)	0.000	0.999	0.001
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.000	0.999	0.001
M87.36 Other secondary osteonecrosis (Lower leg)	0.000	0.999	0.001
M87.34 Other secondary osteonecrosis (Hand)	0.000	0.999	0.001
M87.33 Other secondary osteonecrosis (Forearm)	0.000	0.999	0.001
M87.32 Other secondary osteonecrosis (Upper arm)	0.000	0.999	0.001
M87.31 Other secondary osteonecrosis (Shoulder region)	0.000	0.999	0.001
M87.30 Other secondary osteonecrosis (Multiple sites)	0.000	0.999	0.001
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
R52.9 Pain, unspecified	0.001	0.999	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.000	0.999	0.001
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.000	0.999	0.001
M87.18 Osteonecrosis due to drugs (Other)	0.000	0.999	0.001
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.000	0.999	0.001
M87.16 Osteonecrosis due to drugs (Lower leg)	0.000	0.999	0.001
M87.14 Osteonecrosis due to drugs (Hand)	0.000	0.999	0.001
M87.13 Osteonecrosis due to drugs (Forearm)	0.000	0.999	0.001
M87.12 Osteonecrosis due to drugs (Upper arm)	0.000	0.999	0.001
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.000	0.999	0.001
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.000	0.999	0.001
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.000	0.999	0.001
O81.4 Vacuum extractor delivery	0.000	0.999	0.001
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
C74.1 Medulla of adrenal gland	0.000	0.999	0.001
H81.2 Vestibular neuronitis	0.000	0.999	0.001
J41.0 Simple chronic bronchitis	0.000	0.999	0.001
K07.6 Temporomandibular joint disorders	0.000	0.999	0.001
L27.9 Dermatitis due to unspecified substance taken internally	0.001	0.999	0.000
L27.8 Dermatitis due to other substances taken internally	0.001	0.999	0.000
O47.0 False labour before 37 completed weeks of gestation	0.001	0.999	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
C74 Malignant neoplasm of adrenal gland	0.000	0.999	0.001
U89 Agent resistant to other and unspecified antibiotics	0.001	0.999	0.000
S52.30 Fracture of shaft of radius (closed)	0.001	0.999	0.000
C41.9 Bone and articular cartilage, unspecified	0.001	0.999	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.001	0.999	0.000
D16.4 Bones of skull and face	0.000	0.999	0.001
H02.6 Xanthelasma of eyelid	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations