TreeWAS – Variant ID: rs11084337

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K75 Other inflammatory liver diseases	0.000	0.857	0.143
K70-K77 Diseases of liver	0.000	0.859	0.141
K75.4 Autoimmune hepatitis	0.000	0.861	0.139
K74 Fibrosis and cirrhosis of liver	0.000	0.862	0.138
K73 Chronic hepatitis, not elsewhere classified	0.000	0.863	0.137
K72 Hepatic failure, not elsewhere classified	0.000	0.865	0.135
K73.9 Chronic hepatitis, unspecified	0.000	0.871	0.129
K72.0 Acute and subacute hepatic failure	0.000	0.871	0.129
K74.6 Other and unspecified cirrhosis of liver	0.000	0.873	0.127
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.876	0.123
K75.8 Other specified inflammatory liver diseases	0.000	0.878	0.122
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.881	0.119
K74.3 Primary biliary cirrhosis	0.000	0.885	0.115
K74.0 Hepatic fibrosis	0.000	0.885	0.115
K74.5 Biliary cirrhosis, unspecified	0.000	0.888	0.112
K75.9 Inflammatory liver disease, unspecified	0.000	0.890	0.110
K72.9 Hepatic failure, unspecified	0.000	0.893	0.107
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.896	0.104
K75.2 Nonspecific reactive hepatitis	0.000	0.897	0.103
K75.1 Phlebitis of portal vein	0.000	0.897	0.103
K72.1 Chronic hepatic failure	0.000	0.898	0.102
K77 Liver disorders in diseases classified elsewhere	0.000	0.899	0.101
K74.1 Hepatic sclerosis	0.000	0.899	0.101
K75.0 Abscess of liver	0.000	0.899	0.101
Q21.0 Ventricular septal defect	0.000	0.900	0.100
K74.4 Secondary biliary cirrhosis	0.000	0.900	0.099
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.900	0.099
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.901	0.099
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.901	0.099
Q21 Congenital malformations of cardiac septa	0.000	0.902	0.098
Q21.1 Atrial septal defect	0.000	0.905	0.095
K71 Toxic liver disease	0.000	0.906	0.094
Q28 Other congenital malformations of circulatory system	0.000	0.915	0.085
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.916	0.084
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.916	0.084
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.919	0.081
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.927	0.073
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.927	0.073
Q21.4 Aortopulmonary septal defect	0.000	0.929	0.071
Q21.2 Atrioventricular septal defect	0.000	0.929	0.071
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.930	0.070
K71.8 Toxic liver disease with other disorders of liver	0.000	0.932	0.068
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.932	0.068
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.932	0.068
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.932	0.068
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.932	0.068
K71.2 Toxic liver disease with acute hepatitis	0.000	0.932	0.068
K71.0 Toxic liver disease with cholestasis	0.000	0.932	0.068
Q28.3 Other malformations of cerebral vessels	0.000	0.933	0.067
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.933	0.067
Q27 Other congenital malformations of peripheral vascular system	0.000	0.934	0.066
K71.9 Toxic liver disease, unspecified	0.000	0.934	0.065
Q21.3 Tetralogy of Fallot	0.000	0.937	0.063
Q21.8 Other congenital malformations of cardiac septa	0.000	0.937	0.062
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.939	0.061
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.939	0.061
Q28.1 Other malformations of precerebral vessels	0.000	0.939	0.061
Q26 Congenital malformations of great veins	0.000	0.939	0.061
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.939	0.061
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.940	0.060
Q25 Congenital malformations of great arteries	0.000	0.941	0.059
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.942	0.058
Q24 Other congenital malformations of heart	0.000	0.942	0.057
Q27.3 Peripheral arteriovenous malformation	0.000	0.946	0.054
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.950	0.049
Q23 Congenital malformations of aortic and mitral valves	0.000	0.952	0.048
S62.60 Fracture of other finger (closed)	0.048	0.952	0.000
Q27.4 Congenital phlebectasia	0.000	0.952	0.047
Q27.2 Other congenital malformations of renal artery	0.000	0.952	0.047
Q27.1 Congenital renal artery stenosis	0.000	0.952	0.047
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.952	0.047
S62.6 Fracture of other finger	0.046	0.954	0.000
Q25.1 Coarctation of aorta	0.000	0.955	0.045
Q25.6 Stenosis of pulmonary artery	0.000	0.955	0.045
Q24.6 Congenital heart block	0.000	0.956	0.044
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.956	0.044
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.956	0.044
Q20.6 Isomerism of atrial appendages	0.000	0.956	0.044
Q20.5 Discordant atrioventricular connexion	0.000	0.956	0.044
Q20.4 Double inlet ventricle	0.000	0.956	0.044
Q20.3 Discordant ventriculoarterial connexion	0.000	0.956	0.044
Q20.2 Double outlet left ventricle	0.000	0.956	0.044
Q20.1 Double outlet right ventricle	0.000	0.956	0.044
Q20.0 Common arterial trunk	0.000	0.956	0.044
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.956	0.044
Q26.8 Other congenital malformations of great veins	0.000	0.956	0.044
Q26.6 Portal vein-hepatic artery fistula	0.000	0.956	0.044
Q26.5 Anomalous portal venous connexion	0.000	0.956	0.044
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.956	0.044
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.956	0.044
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.956	0.044
Q26.1 Persistent left superior vena cava	0.000	0.956	0.044
Q26.0 Congenital stenosis of vena cava	0.000	0.956	0.044
Q22.1 Congenital pulmonary valve stenosis	0.000	0.957	0.043
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.957	0.043
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.957	0.043
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.957	0.043
S60-S69 Injuries to the wrist and hand	0.043	0.957	0.000
S62.61 Fracture of other finger (open)	0.043	0.957	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.957	0.042
Q25.8 Other congenital malformations of great arteries	0.000	0.957	0.042
Q25.5 Atresia of pulmonary artery	0.000	0.957	0.042
Q25.2 Atresia of aorta	0.000	0.957	0.042
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.958	0.042
Q22.8 Other congenital malformations of tricuspid valve	0.000	0.958	0.042
Q22.6 Hypoplastic right heart syndrome	0.000	0.958	0.042
Q22.4 Congenital tricuspid stenosis	0.000	0.958	0.042
Q22.3 Other congenital malformations of pulmonary valve	0.000	0.958	0.042
Q22.2 Congenital pulmonary valve insufficiency	0.000	0.958	0.042
Q22.0 Pulmonary valve atresia	0.000	0.958	0.042
S60 Superficial injury of wrist and hand	0.042	0.958	0.000
Q24.0 Dextrocardia	0.000	0.958	0.042
S62 Fracture at wrist and hand level	0.042	0.958	0.000
Q24.3 Pulmonary infundibular stenosis	0.000	0.958	0.041
Q24.2 Cor triatriatum	0.000	0.958	0.041
Q24.1 Levocardia	0.000	0.958	0.041
Q25.0 Patent ductus arteriosus	0.000	0.959	0.041
S61.1 Open wound of finger(s) with damage to nail	0.041	0.959	0.000
Q25.4 Other congenital malformations of aorta	0.000	0.960	0.040
Q24.4 Congenital subaortic stenosis	0.000	0.960	0.040
Q24.5 Malformation of coronary vessels	0.000	0.961	0.039
S60.9 Superficial injury of wrist and hand, unspecified	0.039	0.961	0.000
S61 Open wound of wrist and hand	0.039	0.961	0.000
Q25.3 Stenosis of aorta	0.000	0.962	0.038
Q22.5 Ebstein's anomaly	0.000	0.962	0.038
S69 Other and unspecified injuries of wrist and hand	0.038	0.962	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.962	0.037
S62.2 Fracture of first metacarpal bone	0.036	0.964	0.000
S60.2 Contusion of other parts of wrist and hand	0.036	0.964	0.000
S68 Traumatic amputation of wrist and hand	0.035	0.965	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.035	0.965	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.965	0.035
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.965	0.035
Q23.4 Hypoplastic left heart syndrome	0.000	0.965	0.035
Q23.2 Congenital mitral stenosis	0.000	0.965	0.035
S64 Injury of nerves at wrist and hand level	0.034	0.966	0.000
Q23.3 Congenital mitral insufficiency	0.000	0.966	0.034
S61.7 Multiple open wounds of wrist and hand	0.034	0.966	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.966	0.034
S69.8 Other specified injuries of wrist and hand	0.033	0.967	0.000
S65 Injury of blood vessels at wrist and hand level	0.032	0.968	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.032	0.968	0.000
S60.0 Contusion of finger(s) without damage to nail	0.031	0.968	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.031	0.969	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.031	0.969	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.031	0.969	0.000
S60.8 Other superficial injuries of wrist and hand	0.031	0.969	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.030	0.970	0.000
S69.7 Multiple injuries of wrist and hand	0.030	0.970	0.000
S67 Crushing injury of wrist and hand	0.029	0.971	0.000
S64.4 Injury of digital nerve of other finger	0.029	0.971	0.000
S69.9 Unspecified injury of wrist and hand	0.029	0.971	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.028	0.971	0.000
S65.1 Injury of radial artery at wrist and hand level	0.027	0.973	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.027	0.973	0.000
S64.3 Injury of digital nerve of thumb	0.027	0.973	0.000
S62.3 Fracture of other metacarpal bone	0.026	0.974	0.000
S60.1 Contusion of finger(s) with damage to nail	0.026	0.974	0.000
S62.21 Fracture of first metacarpal bone (open)	0.026	0.974	0.000
G35 Multiple sclerosis	0.000	0.974	0.026
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.025	0.975	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.025	0.975	0.000
S68.4 Traumatic amputation of hand at wrist level	0.025	0.975	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.025	0.975	0.000
S63.2 Multiple dislocations of fingers	0.025	0.975	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.975	0.025
S62.4 Multiple fractures of metacarpal bones	0.025	0.975	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.025	0.975	0.000
S64.8 Injury of other nerves at wrist and hand level	0.025	0.975	0.000
S62.1 Fracture of other carpal bone(s)	0.024	0.975	0.000
S62.7 Multiple fractures of fingers	0.024	0.975	0.000
S62.5 Fracture of thumb	0.024	0.976	0.000
S64.1 Injury of median nerve at wrist and hand level	0.024	0.976	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.024	0.976	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.024	0.976	0.000
S63.6 Sprain and strain of finger(s)	0.024	0.976	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.023	0.977	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.023	0.977	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.023	0.977	0.000
S65.3 Injury of deep palmar arch	0.023	0.977	0.000
S65.2 Injury of superficial palmar arch	0.023	0.977	0.000
S65.4 Injury of blood vessel(s) of thumb	0.023	0.977	0.000
S63.0 Dislocation of wrist	0.023	0.977	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.023	0.977	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.023	0.977	0.000
S63.5 Sprain and strain of wrist	0.023	0.977	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.023	0.977	0.000
S63.1 Dislocation finger	0.022	0.977	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.023	0.977	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.022	0.978	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.022	0.978	0.000
S62.31 Fracture of other metacarpal bone (open)	0.022	0.978	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.021	0.979	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.020	0.979	0.000
K70 Alcoholic liver disease	0.000	0.980	0.020
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.019	0.981	0.000
S61.0 Open wound of finger(s) without damage to nail	0.019	0.981	0.000
S65.5 Injury of blood vessel(s) of other finger	0.019	0.981	0.000
K76 Other diseases of liver	0.000	0.981	0.019
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.019	0.981	0.000
S62.50 Fracture of thumb (closed)	0.018	0.982	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.018	0.982	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.018	0.982	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.017	0.983	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.017	0.983	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.983	0.017
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.016	0.983	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.016	0.983	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.016	0.983	0.000
S62.70 Multiple fractures of fingers (closed)	0.016	0.984	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.016	0.984	0.000
K76.8 Other specified diseases of liver	0.000	0.984	0.016
N30.2 Other chronic cystitis	0.000	0.984	0.016
S68.0 Traumatic amputation of thumb (complete)(partial)	0.015	0.984	0.000
K70.4 Alcoholic hepatic failure	0.000	0.984	0.015
K76.7 Hepatorenal syndrome	0.000	0.985	0.015
S62.71 Multiple fractures of fingers (open)	0.014	0.985	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.014	0.986	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.014	0.986	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.014	0.986	0.000
D12.4 Descending colon	0.014	0.986	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.986	0.014
K76.4 Peliosis hepatis	0.000	0.986	0.014
K76.3 Infarction of liver	0.000	0.986	0.014
K76.2 Central haemorrhagic necrosis of liver	0.000	0.986	0.014
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.013	0.987	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.012	0.987	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.012	0.987	0.000
Z96.8 Presence of other specified functional implants	0.012	0.988	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.012	0.988	0.001
K76.1 Chronic passive congestion of liver	0.000	0.988	0.012
K70.0 Alcoholic fatty liver	0.000	0.989	0.011
S62.51 Fracture of thumb (open)	0.011	0.989	0.000
N41.1 Chronic prostatitis	0.010	0.990	0.000
K60.3 Anal fistula	0.010	0.990	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.010	0.990	0.000
K70.1 Alcoholic hepatitis	0.000	0.991	0.009
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.992	0.000
R22.0 Localised swelling, mass and lump, head	0.007	0.993	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.993	0.007
S61.8 Open wound of other parts of wrist and hand	0.007	0.993	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.007	0.993	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.994	0.006
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.994	0.006
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.994	0.006
I49.9 Cardiac arrhythmia, unspecified	0.006	0.994	0.000
C17.2 Ileum	0.006	0.994	0.000
I44.1 Atrioventricular block, second degree	0.000	0.994	0.006
I08.0 Disorders of both mitral and aortic valves	0.000	0.994	0.006
C71.1 Frontal lobe	0.000	0.995	0.005
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.995	0.005
I31.9 Disease of pericardium, unspecified	0.005	0.995	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.005	0.995	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.995	0.005
Z13.1 Special screening examination for diabetes mellitus	0.005	0.995	0.000
C17 Malignant neoplasm of small intestine	0.005	0.995	0.000
I08 Multiple valve diseases	0.000	0.995	0.005
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
C17.0 Duodenum	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
G36 Other acute disseminated demyelination	0.000	0.995	0.005
G58.8 Other specified mononeuropathies	0.005	0.995	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.004	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.995	0.005
M79.2 Neuralgia and neuritis, unspecified	0.004	0.996	0.000
C17.9 Small intestine, unspecified	0.004	0.996	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.996	0.004
G58.9 Mononeuropathy, unspecified	0.004	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.996	0.004
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.000	0.996	0.004
C17.8 Overlapping lesion of small intestine	0.004	0.996	0.000
C17.3 Meckel's diverticulum	0.004	0.996	0.000
K76.9 Liver disease, unspecified	0.000	0.996	0.004
C17.1 Jejunum	0.004	0.996	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.996	0.004
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.004	0.996	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.996	0.004
G36.8 Other specified acute disseminated demyelination	0.000	0.996	0.004
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.996	0.004
G58 Other mononeuropathies	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.004	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.996	0.003
M71.38 Other bursal cyst (Other)	0.004	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.996	0.003
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.003	0.996	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.003	0.996	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.003	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.997	0.003
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.003	0.997	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.997	0.003
G58.7 Mononeuritis multiplex	0.003	0.997	0.000
C20 Malignant neoplasm of rectum	0.003	0.997	0.000
R26.0 Ataxic gait	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.997	0.003
G37.4 Subacute necrotising myelitis	0.000	0.997	0.003
G37.2 Central pontine myelinolysis	0.000	0.997	0.003
G37.1 Central demyelination of corpus callosum	0.000	0.997	0.003
G37.0 Diffuse sclerosis	0.000	0.997	0.003
M71.3 Other bursal cyst	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.000	0.997	0.003
Z85.6 Personal history of leukaemia	0.003	0.997	0.000
C21.0 Anus, unspecified	0.003	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.000	0.997	0.003
M71.37 Other bursal cyst (Ankle and foot)	0.003	0.997	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
W22.9 Unspecified place	0.000	0.997	0.003
C24.0 Extrahepatic bile duct	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.000	0.997	0.003
R47.1 Dysarthria and anarthria	0.003	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.997	0.003
M71.36 Other bursal cyst (Lower leg)	0.003	0.997	0.000
G58.0 Intercostal neuropathy	0.002	0.997	0.000
C21 Malignant neoplasm of anus and anal canal	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.000	0.997	0.002
M71.34 Other bursal cyst (Hand)	0.002	0.997	0.000
C15-C26 Malignant neoplasms of digestive organs	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.002	0.997	0.000
Q66.7 Pes cavus	0.000	0.998	0.002
M71.39 Other bursal cyst (Site unspecified)	0.002	0.998	0.000
M71.35 Other bursal cyst (Pelvic region and thigh)	0.002	0.998	0.000
M71.33 Other bursal cyst (Forearm)	0.002	0.998	0.000
M71.32 Other bursal cyst (Upper arm)	0.002	0.998	0.000
M71.31 Other bursal cyst (Shoulder region)	0.002	0.998	0.000
M71.30 Other bursal cyst (Multiple sites)	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.998	0.002
C22.1 Intrahepatic bile duct carcinoma	0.002	0.998	0.000
C26.0 Intestinal tract, part unspecified	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
K63.9 Disease of intestine, unspecified	0.002	0.998	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.002
K76.6 Portal hypertension	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
Q66.5 Congenital pes planus	0.000	0.998	0.002
Q66.4 Talipes calcaneovalgus	0.000	0.998	0.002
Q66.1 Talipes calcaneovarus	0.000	0.998	0.002
Q66.2 Metatarsus varus	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.000	0.998	0.002
X51.9 Unspecified place	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
C21.2 Cloacogenic zone	0.002	0.998	0.000
C24.1 Ampulla of Vater	0.002	0.998	0.000
C23 Malignant neoplasm of gallbladder	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
O90.2 Haematoma of obstetric wound	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
C24.8 Overlapping lesion of biliary tract	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
O64.1 Obstructed labour due to breech presentation	0.000	0.998	0.002
S01.5 Open wound of lip and oral cavity	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.998	0.002
M23.5 Chronic instability of knee	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.998	0.002
K60 Fissure and fistula of anal and rectal regions	0.002	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.002	0.998	0.000
C26.8 Overlapping lesion of digestive system	0.002	0.998	0.000
C26.1 Spleen	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.000	0.998	0.002
Q73 Reduction defects of unspecified limb	0.000	0.998	0.002
Q72 Reduction defects of lower limb	0.000	0.998	0.002
Q71 Reduction defects of upper limb	0.000	0.998	0.002
Q69 Polydactyly	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
H35.6 Retinal haemorrhage	0.000	0.998	0.002
N41 Inflammatory diseases of prostate	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.998	0.002
Q76.8 Other congenital malformations of bony thorax	0.000	0.998	0.002
Q76.7 Congenital malformation of sternum	0.000	0.998	0.002
Q76.6 Other congenital malformations of ribs	0.000	0.998	0.002
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.998	0.002
Q76.2 Congenital spondylolisthesis	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.000	0.998	0.002
Q70 Syndactyly	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
Q75 Other congenital malformations of skull and face bones	0.000	0.998	0.002
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M70.22 Olecranon bursitis-Upper arm	0.002	0.998	0.000
Q76.5 Cervical rib	0.000	0.998	0.002
Q61 Cystic kidney disease	0.002	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.000	0.998	0.002
Q76.1 Klippel-Feil syndrome	0.000	0.998	0.002
Q77.4 Achondroplasia	0.000	0.998	0.002
O90 Complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.000	0.998	0.002
Q30-Q34 Congenital malformations of the respiratory system	0.000	0.998	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.000	0.998	0.002
Q68.4 Congenital bowing of tibia and fibula	0.000	0.998	0.002
Q68.3 Congenital bowing of femur	0.000	0.998	0.002
Q68.2 Congenital deformity of knee	0.000	0.998	0.002
Q68.1 Congenital deformity of hand	0.000	0.998	0.002
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.000	0.998	0.002
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.998	0.002
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
Q35 Cleft palate	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
C22.7 Other specified carcinomas of liver	0.002	0.998	0.000
C22.4 Other sarcomas of liver	0.002	0.998	0.000
C22.3 Angiosarcoma of liver	0.002	0.998	0.000
C22.2 Hepatoblastoma	0.002	0.998	0.000
C54.9 Corpus uteri, unspecified	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
Q36 Cleft lip	0.000	0.998	0.001
D75.2 Essential thrombocytosis	0.000	0.998	0.002
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.001
M54.9 Dorsalgia, unspecified	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.000	0.998	0.001
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.998	0.001
Q77.7 Spondyloepiphyseal dysplasia	0.000	0.998	0.001
Q77.6 Chondroectodermal dysplasia	0.000	0.998	0.001
Q77.5 Diastrophic dysplasia	0.000	0.998	0.001
Q77.3 Chondrodysplasia punctata	0.000	0.998	0.001
Q77.2 Short rib syndrome	0.000	0.998	0.001
Q77.1 Thanatophoric short stature	0.000	0.998	0.001
Q77.0 Achondrogenesis	0.000	0.998	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
Q12 Congenital lens malformations	0.000	0.998	0.002
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.998	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.000	0.998	0.002
C26.9 Ill-defined sites within the digestive system	0.001	0.998	0.000
H60.8 Other otitis externa	0.000	0.998	0.002
K60.4 Rectal fistula	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.000	0.998	0.001
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.001	0.998	0.000
Q12.0 Congenital cataract	0.000	0.998	0.002
Q69.9 Polydactyly, unspecified	0.000	0.998	0.001
Q69.2 Accessory toe(s)	0.000	0.998	0.001
Q69.1 Accessory thumb(s)	0.000	0.998	0.001
Q69.0 Accessory finger(s)	0.000	0.998	0.001
Q71.9 Reduction defect of upper limb, unspecified	0.000	0.998	0.001
Q71.8 Other reduction defects of upper limb(s)	0.000	0.998	0.001
Q71.6 Lobster-claw hand	0.000	0.998	0.001
Q71.5 Longitudinal reduction defect of ulna	0.000	0.998	0.001
Q71.4 Longitudinal reduction defect of radius	0.000	0.998	0.001
Q71.3 Congenital absence of hand and finger(s)	0.000	0.998	0.001
Q71.2 Congenital absence of both forearm and hand	0.000	0.998	0.001
Q71.1 Congenital absence of upper arm and forearm with hand present	0.000	0.998	0.001
Q71.0 Congenital complete absence of upper limb(s)	0.000	0.998	0.001
Q72.9 Reduction defect of lower limb, unspecified	0.000	0.998	0.001
Q72.8 Other reduction defects of lower limb(s)	0.000	0.998	0.001
Q72.7 Split foot	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations