TreeWAS – Variant ID: rs11088872

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F20.9 Schizophrenia, unspecified	0.000	0.944	0.056
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.043	0.957	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.042	0.958	0.000
F20 Schizophrenia	0.000	0.958	0.042
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.038	0.962	0.000
F20.5 Residual schizophrenia	0.000	0.964	0.036
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.036	0.964	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.036	0.964	0.000
F20.0 Paranoid schizophrenia	0.000	0.964	0.036
M84 Disorders of continuity of bone	0.034	0.966	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.034	0.966	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.034	0.966	0.000
M84.0 Malunion of fracture	0.033	0.967	0.000
M84.03 Malunion of fracture (Forearm)	0.032	0.968	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.031	0.969	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.031	0.969	0.000
F20.6 Simple schizophrenia	0.000	0.969	0.031
F20.4 Postschizophrenic depression	0.000	0.969	0.031
F20.3 Undifferentiated schizophrenia	0.000	0.969	0.031
F20.2 Catatonic schizophrenia	0.000	0.969	0.031
F20.1 Hebephrenic schizophrenia	0.000	0.969	0.031
F20.8 Other schizophrenia	0.000	0.970	0.030
M84.07 Malunion of fracture (Ankle and foot)	0.029	0.971	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.028	0.971	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.028	0.972	0.000
M84.2 Delayed union of fracture	0.028	0.972	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.027	0.972	0.000
M84.8 Other disorders of continuity of bone	0.026	0.974	0.000
K62.0 Anal polyp	0.025	0.975	0.000
M84.08 Malunion of fracture (Other)	0.025	0.975	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.025	0.975	0.000
M84.02 Malunion of fracture (Upper arm)	0.024	0.975	0.000
M84.9 Disorder of continuity of bone, unspecified	0.024	0.975	0.000
M84.09 Malunion of fracture (Site unspecified)	0.024	0.976	0.000
M84.00 Malunion of fracture (Multiple sites)	0.024	0.976	0.000
M84.3 Stress fracture, not elsewhere classified	0.023	0.977	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.022	0.978	0.000
M84.26 Delayed union of fracture (Lower leg)	0.022	0.978	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.020	0.979	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.020	0.980	0.000
M84.28 Delayed union of fracture (Other)	0.020	0.980	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.020	0.980	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.020	0.980	0.000
M84.24 Delayed union of fracture (Hand)	0.020	0.980	0.000
M84.23 Delayed union of fracture (Forearm)	0.020	0.980	0.000
M84.22 Delayed union of fracture (Upper arm)	0.020	0.980	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.020	0.980	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.019	0.981	0.000
M84.88 Other disorders of continuity of bone (Other)	0.019	0.981	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.019	0.981	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.019	0.981	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.019	0.981	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.019	0.981	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.019	0.981	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.019	0.981	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.019	0.981	0.000
M84.4 Pathological fracture, not elsewhere classified	0.018	0.981	0.000
M84.01 Malunion of fracture (Shoulder region)	0.018	0.982	0.000
M84.04 Malunion of fracture (Hand)	0.018	0.982	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.018	0.982	0.000
T45.0 Antiallergic and antiemetic drugs	0.018	0.982	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.018	0.982	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.018	0.982	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.018	0.982	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.018	0.982	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.018	0.982	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.018	0.982	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.018	0.982	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.018	0.982	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.018	0.982	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.018	0.982	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.017	0.983	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.017	0.983	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.017	0.983	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.017	0.983	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.017	0.983	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.017	0.983	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.017	0.983	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.017	0.983	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.017	0.983	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.017	0.983	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.017	0.983	0.000
M84.06 Malunion of fracture (Lower leg)	0.016	0.983	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.015	0.985	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.015	0.985	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T43.9 Psychotropic drug, unspecified	0.015	0.985	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.014	0.985	0.000
T43.6 Psychostimulants with abuse potential	0.014	0.986	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.014	0.986	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.013	0.986	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.013	0.986	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.013	0.986	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.013	0.986	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.013	0.986	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.013	0.986	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.013	0.986	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.013	0.987	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.013	0.987	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.012	0.987	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.012	0.987	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.012	0.988	0.000
T45.8 Other primarily systemic and haematological agents	0.012	0.988	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.012	0.988	0.000
T45.6 Fibrinolysis-affecting drugs	0.012	0.988	0.000
T45.4 Iron and its compounds	0.012	0.988	0.000
T45.3 Enzymes, not elsewhere classified	0.012	0.988	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.012	0.988	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.988	0.000
T45.5 Anticoagulants	0.011	0.988	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.011	0.989	0.000
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.011	0.989	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.011	0.989	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.011	0.989	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.011	0.989	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.011	0.989	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.989	0.011
T36 Poisoning by systemic antibiotics	0.011	0.989	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.989	0.011
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.990	0.000
T45.2 Vitamins, not elsewhere classified	0.010	0.990	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.010	0.990	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.010	0.990	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.990	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.990	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.010	0.990	0.000
T44.0 Anticholinesterase agents	0.010	0.990	0.000
T50.8 Diagnostic agents	0.010	0.990	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.010	0.990	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.010	0.990	0.000
T50.4 Drugs affecting uric acid metabolism	0.009	0.990	0.000
T47.2 Stimulant laxatives	0.009	0.990	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.009	0.991	0.000
F45.8 Other somatoform disorders	0.000	0.991	0.009
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.009	0.991	0.000
D73.0 Hyposplenism	0.000	0.991	0.009
T39.0 Salicylates	0.009	0.991	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.009	0.991	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
T47.7 Emetics	0.009	0.991	0.000
T47.6 Antidiarrhoeal drugs	0.009	0.991	0.000
T47.5 Digestants	0.009	0.991	0.000
T47.4 Other laxatives	0.009	0.991	0.000
T47.3 Saline and osmotic laxatives	0.009	0.991	0.000
T47.0 Histamine H(2)-receptor antagonists	0.009	0.991	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.008	0.991	0.001
F25 Schizoaffective disorders	0.000	0.991	0.009
T48.6 Antiasthmatics, not elsewhere classified	0.008	0.991	0.000
L43.9 Lichen planus, unspecified	0.000	0.991	0.009
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.008	0.992	0.000
T48.5 Anti-common-cold drugs	0.008	0.992	0.000
T48.4 Expectorants	0.008	0.992	0.000
T48.3 Antitussives	0.008	0.992	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.008	0.992	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.008	0.992	0.000
T48.0 Oxytocic drugs	0.008	0.992	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T41.5 Therapeutic gases	0.008	0.992	0.000
T41.4 Anaesthetic, unspecified	0.008	0.992	0.000
T41.3 Local anaesthetics	0.008	0.992	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.992	0.000
T41.1 Intravenous anaesthetics	0.008	0.992	0.000
T41.0 Inhaled anaesthetics	0.008	0.992	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.008	0.992	0.000
T37.5 Antiviral drugs	0.008	0.992	0.000
T37.4 Anthelminthics	0.008	0.992	0.000
T37.3 Other antiprotozoal drugs	0.008	0.992	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.008	0.992	0.000
T37.1 Antimycobacterial drugs	0.008	0.992	0.000
T37.0 Sulphonamides	0.008	0.992	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.992	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.008	0.992	0.000
T49.9 Topical agent, unspecified	0.008	0.992	0.000
T49.8 Other topical agents	0.008	0.992	0.000
T49.7 Dental drugs, topically applied	0.008	0.992	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.008	0.992	0.000
T49.5 Ophthalmological drugs and preparations	0.008	0.992	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.992	0.000
T49.3 Emollients, demulcents and protectants	0.008	0.992	0.000
T49.2 Local astringents and local detergents	0.008	0.992	0.000
T49.1 Antipruritics	0.008	0.992	0.000
G93.3 Postviral fatigue syndrome	0.008	0.992	0.000
T36.9 Systemic antibiotic, unspecified	0.008	0.992	0.000
T36.8 Other systemic antibiotics	0.008	0.992	0.000
T36.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
T36.6 Rifamycins	0.008	0.992	0.000
T36.5 Aminoglycosides	0.008	0.992	0.000
T36.4 Tetracyclines	0.008	0.992	0.000
T36.2 Chloramphenicol group	0.008	0.992	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.008	0.992	0.000
F28 Other nonorganic psychotic disorders	0.000	0.992	0.008
F24 Induced delusional disorder	0.000	0.992	0.008
F21 Schizotypal disorder	0.000	0.992	0.008
T36.3 Macrolides	0.008	0.992	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.992	0.000
T42.0 Hydantoin derivatives	0.008	0.992	0.000
T36.0 Penicillins	0.007	0.993	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.993	0.007
T39.4 Antirheumatics, not elsewhere classified	0.007	0.993	0.000
T39.2 Pyrazolone derivatives	0.007	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.993	0.000
T42.3 Barbiturates	0.007	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.007	0.993	0.000
F29 Unspecified nonorganic psychosis	0.000	0.993	0.007
J92.0 Pleural plaque with presence of asbestos	0.007	0.993	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.993	0.007
F25.8 Other schizoaffective disorders	0.000	0.993	0.006
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
F25.2 Schizoaffective disorder, mixed type	0.000	0.994	0.006
F25.1 Schizoaffective disorder, depressive type	0.000	0.994	0.006
F23 Acute and transient psychotic disorders	0.000	0.994	0.006
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.006	0.994	0.000
T40.8 Lysergide [LSD]	0.006	0.994	0.000
T40.7 Cannabis (derivatives)	0.006	0.994	0.000
T40.1 Heroin	0.006	0.994	0.000
T40.0 Opium	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
F22 Persistent delusional disorders	0.000	0.994	0.006
T40.5 Cocaine	0.006	0.994	0.000
T40.4 Other synthetic narcotics	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.006	0.994	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.994	0.006
I08 Multiple valve diseases	0.000	0.995	0.005
E22.0 Acromegaly and pituitary gigantism	0.000	0.995	0.005
K10.2 Inflammatory conditions of jaws	0.000	0.995	0.005
E27 Other disorders of adrenal gland	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
O70.0 First degree perineal laceration during delivery	0.000	0.995	0.005
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.995	0.000
T38.7 Androgens and anabolic congeners	0.004	0.995	0.000
T38.5 Other oestrogens and progestogens	0.004	0.995	0.000
T38.4 Oral contraceptives	0.004	0.995	0.000
T38.2 Antithyroid drugs	0.004	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
E22 Hyperfunction of pituitary gland	0.000	0.995	0.005
F23.8 Other acute and transient psychotic disorders	0.000	0.995	0.005
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.995	0.005
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.995	0.005
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.995	0.005
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.995	0.005
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.995	0.000
T46.7 Peripheral vasodilators	0.004	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
T42.1 Iminostilbenes	0.004	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.995	0.005
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
F22.8 Other persistent delusional disorders	0.000	0.995	0.004
J92 Pleural plaque	0.005	0.995	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.995	0.000
Q44.6 Cystic disease of liver	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.995	0.005
I08.9 Multiple valve disease, unspecified	0.000	0.995	0.005
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
I08.8 Other multiple valve diseases	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.996	0.004
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.996	0.004
C78.2 Secondary malignant neoplasm of pleura	0.000	0.996	0.004
I08.0 Disorders of both mitral and aortic valves	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
E27.2 Addisonian crisis	0.000	0.996	0.004
E20-E35 Disorders of other endocrine glands	0.000	0.996	0.004
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
E24 Cushing's syndrome	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.000	0.996	0.004
E27.0 Other adrenocortical overactivity	0.000	0.996	0.004
T38.1 Thyroid hormones and substitutes	0.003	0.996	0.001
T42.4 Benzodiazepines	0.004	0.996	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.996	0.004
S22.20 Fracture of sternum (closed)	0.000	0.996	0.004
E22.8 Other hyperfunction of pituitary gland	0.000	0.996	0.004
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
L43 Lichen planus	0.000	0.996	0.004
Q50.5 Embryonic cyst of broad ligament	0.003	0.996	0.000
E20 Hypoparathyroidism	0.000	0.996	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.996	0.003
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.997	0.000
Q50.2 Congenital torsion of ovary	0.003	0.997	0.000
Q50.1 Developmental ovarian cyst	0.003	0.997	0.000
Q50.0 Congenital absence of ovary	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
I70.2 Atherosclerosis of arteries of the extremities	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
D73 Diseases of spleen	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
E25 Adrenogenital disorders	0.000	0.997	0.003
F22.0 Delusional disorder	0.000	0.997	0.003
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
E34 Other endocrine disorders	0.000	0.997	0.003
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.000	0.997	0.003
Q61 Cystic kidney disease	0.003	0.997	0.000
L03.0 Cellulitis of finger and toe	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.003
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.003
E24.1 Nelson's syndrome	0.000	0.997	0.003
Q53 Undescended testicle	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.003
E29 Testicular dysfunction	0.000	0.997	0.003
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
D73.1 Hypersplenism	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.997	0.001
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
L43.3 Subacute (active) lichen planus	0.000	0.997	0.003
L43.2 Lichenoid drug reaction	0.000	0.997	0.003
L43.1 Bullous lichen planus	0.000	0.997	0.003
L43.0 Hypertrophic lichen planus	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
F81 Specific developmental disorders of scholastic skills	0.000	0.997	0.003
E20.8 Other hypoparathyroidism	0.000	0.997	0.003
E20.1 Pseudohypoparathyroidism	0.000	0.997	0.003
E20.0 Idiopathic hypoparathyroidism	0.000	0.997	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.003
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
D73.4 Cyst of spleen	0.000	0.997	0.003
D73.3 Abscess of spleen	0.000	0.997	0.003
E26 Hyperaldosteronism	0.000	0.997	0.003
R49.0 Dysphonia	0.003	0.997	0.000
D73.9 Disease of spleen, unspecified	0.000	0.997	0.003
D73.2 Chronic congestive splenomegaly	0.000	0.997	0.003
T79.3 Post-traumatic wound infection, not elsewhere classified	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.997	0.002
E25.8 Other adrenogenital disorders	0.000	0.997	0.002
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
E87.7 Fluid overload	0.000	0.997	0.003
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.000	0.997	0.002
E34.4 Constitutional tall stature	0.000	0.997	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.002
Q40.1 Congenital hiatus hernia	0.002	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.002	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.997	0.002
E30.8 Other disorders of puberty	0.000	0.997	0.002
E30.1 Precocious puberty	0.000	0.997	0.002
E30.0 Delayed puberty	0.000	0.997	0.002
E32.9 Disease of thymus, unspecified	0.000	0.997	0.002
E32.8 Other diseases of thymus	0.000	0.997	0.002
E32.1 Abscess of thymus	0.000	0.997	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.997	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.997	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.997	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.997	0.002
L43.8 Other lichen planus	0.000	0.997	0.002
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.997	0.003
M82 Osteoporosis in diseases classified elsewhere	0.002	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
L60.8 Other nail disorders	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
E28 Ovarian dysfunction	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.000	0.998	0.002
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
E29.1 Testicular hypofunction	0.000	0.998	0.002
F81.8 Other developmental disorders of scholastic skills	0.000	0.998	0.002
F81.3 Mixed disorder of scholastic skills	0.000	0.998	0.002
F81.2 Specific disorder of arithmetical skills	0.000	0.998	0.002
F81.1 Specific spelling disorder	0.000	0.998	0.002
F81.0 Specific reading disorder	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.998	0.002
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
H35.9 Retinal disorder, unspecified	0.000	0.998	0.002
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
S52.51 Fracture of lower end of radius (open)	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations