TreeWAS – Variant ID: rs11105468

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.526	0.474	0.000
H66 Suppurative and unspecified otitis media	0.000	0.576	0.424
H65-H75 Diseases of middle ear and mastoid	0.000	0.576	0.424
H66.3 Other chronic suppurative otitis media	0.000	0.583	0.417
H72 Perforation of tympanic membrane	0.000	0.586	0.414
H71 Cholesteatoma of middle ear	0.000	0.591	0.409
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.600	0.400
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.625	0.375
H74 Other disorders of middle ear and mastoid	0.000	0.632	0.368
H70 Mastoiditis and related conditions	0.000	0.633	0.367
H66.4 Suppurative otitis media, unspecified	0.000	0.646	0.354
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.354	0.646	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.654	0.346
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.658	0.342
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.340	0.660	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.661	0.339
T36-T50 Poisoning by drugs, medicaments and biological substances	0.335	0.665	0.000
H70.9 Mastoiditis, unspecified	0.000	0.666	0.334
H72.1 Attic perforation of tympanic membrane	0.000	0.669	0.331
H69 Other disorders of Eustachian tube	0.000	0.673	0.327
T46 Poisoning by agents primarily affecting the cardiovascular system	0.325	0.675	0.000
H66.0 Acute suppurative otitis media	0.000	0.679	0.321
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.689	0.311
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.694	0.306
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.306	0.694	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.696	0.304
H68 Eustachian salpingitis and obstruction	0.000	0.696	0.304
H67 Otitis media in diseases classified elsewhere	0.000	0.696	0.304
T46.1 Calcium-channel blockers	0.293	0.707	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.293	0.707	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.290	0.710	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.286	0.714	0.000
H74.0 Tympanosclerosis	0.000	0.717	0.283
T39.0 Salicylates	0.281	0.719	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.279	0.721	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.277	0.723	0.000
H70.1 Chronic mastoiditis	0.000	0.728	0.272
T39.1 4-Aminophenol derivatives	0.272	0.728	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.271	0.729	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.269	0.731	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.734	0.266
I10-I15 Hypertensive diseases	0.266	0.734	0.000
T36 Poisoning by systemic antibiotics	0.264	0.736	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.264	0.736	0.000
H70.2 Petrositis	0.000	0.737	0.263
H70.0 Acute mastoiditis	0.000	0.737	0.263
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.254	0.746	0.000
T42.0 Hydantoin derivatives	0.254	0.746	0.000
I11 Hypertensive heart disease	0.251	0.749	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.753	0.247
T47.4 Other laxatives	0.245	0.755	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.244	0.756	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.244	0.756	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.244	0.756	0.000
T42.3 Barbiturates	0.244	0.756	0.000
T42.2 Succinimides and oxazolidinediones	0.244	0.756	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.242	0.758	0.000
H66.9 Otitis media, unspecified	0.000	0.759	0.241
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.240	0.760	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.240	0.760	0.000
T40.2 Other opioids	0.239	0.760	0.000
H69.0 Patulous Eustachian tube	0.000	0.766	0.234
T40.4 Other synthetic narcotics	0.234	0.766	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.233	0.767	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.233	0.767	0.000
T46.7 Peripheral vasodilators	0.233	0.767	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.233	0.767	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.233	0.767	0.000
T42.4 Benzodiazepines	0.230	0.770	0.000
H74.1 Adhesive middle ear disease	0.000	0.771	0.229
H70.8 Other mastoiditis and related conditions	0.000	0.771	0.228
T48.5 Anti-common-cold drugs	0.227	0.773	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.775	0.225
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.224	0.776	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.223	0.777	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.222	0.777	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.221	0.779	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.780	0.220
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.220	0.780	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.220	0.780	0.000
T47.7 Emetics	0.220	0.780	0.000
T47.6 Antidiarrhoeal drugs	0.220	0.780	0.000
T47.5 Digestants	0.220	0.780	0.000
T47.3 Saline and osmotic laxatives	0.220	0.780	0.000
T47.2 Stimulant laxatives	0.220	0.780	0.000
T47.0 Histamine H(2)-receptor antagonists	0.220	0.780	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.781	0.219
T48.6 Antiasthmatics, not elsewhere classified	0.218	0.782	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.782	0.218
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.782	0.218
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.782	0.218
H68.1 Obstruction of Eustachian tube	0.000	0.782	0.218
H68.0 Eustachian salpingitis	0.000	0.782	0.218
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.782	0.218
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.782	0.218
T36.8 Other systemic antibiotics	0.217	0.783	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.214	0.786	0.000
T39.4 Antirheumatics, not elsewhere classified	0.210	0.790	0.000
T39.2 Pyrazolone derivatives	0.210	0.790	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.206	0.794	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.205	0.795	0.000
T40.8 Lysergide [LSD]	0.205	0.795	0.000
T40.7 Cannabis (derivatives)	0.205	0.795	0.000
T40.5 Cocaine	0.205	0.795	0.000
T40.3 Methadone	0.205	0.795	0.000
T40.1 Heroin	0.205	0.795	0.000
T40.0 Opium	0.205	0.795	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.203	0.797	0.000
H73 Other disorders of tympanic membrane	0.000	0.800	0.200
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.200	0.800	0.000
T48.4 Expectorants	0.200	0.800	0.000
T48.3 Antitussives	0.200	0.800	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.200	0.800	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.200	0.800	0.000
T48.0 Oxytocic drugs	0.200	0.800	0.000
H74.4 Polyp of middle ear	0.000	0.800	0.199
T36.3 Macrolides	0.198	0.802	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.194	0.805	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.194	0.805	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.194	0.805	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.194	0.805	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.194	0.805	0.000
T44.0 Anticholinesterase agents	0.194	0.805	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.193	0.807	0.000
T37.5 Antiviral drugs	0.193	0.807	0.000
T37.4 Anthelminthics	0.193	0.807	0.000
T37.3 Other antiprotozoal drugs	0.193	0.807	0.000
T37.1 Antimycobacterial drugs	0.193	0.807	0.000
T37.0 Sulphonamides	0.193	0.807	0.000
T40.6 Other and unspecified narcotics	0.192	0.808	0.000
I13 Hypertensive heart and renal disease	0.191	0.809	0.000
T36.9 Systemic antibiotic, unspecified	0.190	0.810	0.000
T36.7 Antifungal antibiotics, systemically used	0.190	0.810	0.000
T36.6 Rifamycins	0.190	0.810	0.000
T36.5 Aminoglycosides	0.190	0.810	0.000
T36.4 Tetracyclines	0.190	0.810	0.000
T36.2 Chloramphenicol group	0.190	0.810	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.190	0.810	0.000
T42.1 Iminostilbenes	0.189	0.811	0.000
H80-H83 Diseases of inner ear	0.000	0.819	0.181
H72.0 Central perforation of tympanic membrane	0.000	0.823	0.177
T36.0 Penicillins	0.176	0.824	0.000
H80 Otosclerosis	0.000	0.826	0.174
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.174	0.826	0.000
T41.5 Therapeutic gases	0.172	0.828	0.000
T41.4 Anaesthetic, unspecified	0.172	0.828	0.000
T41.3 Local anaesthetics	0.172	0.828	0.000
T41.2 Other and unspecified general anaesthetics	0.172	0.828	0.000
T41.1 Intravenous anaesthetics	0.172	0.828	0.000
T41.0 Inhaled anaesthetics	0.172	0.828	0.000
T49.9 Topical agent, unspecified	0.172	0.828	0.000
T49.8 Other topical agents	0.172	0.828	0.000
T49.7 Dental drugs, topically applied	0.172	0.828	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.172	0.828	0.000
T49.5 Ophthalmological drugs and preparations	0.172	0.828	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.172	0.828	0.000
T49.3 Emollients, demulcents and protectants	0.172	0.828	0.000
T49.2 Local astringents and local detergents	0.172	0.828	0.000
T49.1 Antipruritics	0.172	0.828	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.172	0.828	0.000
H80.9 Otosclerosis, unspecified	0.000	0.830	0.170
H90-H95 Other disorders of ear	0.000	0.836	0.164
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.159	0.841	0.000
T38.9 Other and unspecified hormone antagonists	0.158	0.841	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.158	0.841	0.000
T38.7 Androgens and anabolic congeners	0.158	0.841	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.158	0.841	0.000
T38.5 Other oestrogens and progestogens	0.158	0.841	0.000
T38.4 Oral contraceptives	0.158	0.841	0.000
T38.2 Antithyroid drugs	0.158	0.841	0.000
T38.0 Glucocorticoids and synthetic analogues	0.158	0.841	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.150	0.850	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.150	0.850	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.852	0.148
I11.0 Hypertensive heart disease with (congestive) heart failure	0.147	0.853	0.000
H73.1 Chronic myringitis	0.000	0.856	0.144
H73.0 Acute myringitis	0.000	0.856	0.144
H60-H62 Diseases of external ear	0.000	0.857	0.143
T38.1 Thyroid hormones and substitutes	0.138	0.862	0.000
T50.1 Loop [high-ceiling] diuretics	0.138	0.862	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.137	0.863	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.137	0.863	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.137	0.863	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.137	0.863	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.135	0.865	0.000
I12 Hypertensive renal disease	0.132	0.868	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.870	0.130
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.870	0.130
H95.1 Other disorders following mastoidectomy	0.000	0.871	0.129
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.128	0.871	0.000
T50.4 Drugs affecting uric acid metabolism	0.128	0.872	0.000
I15 Secondary hypertension	0.128	0.872	0.000
H80.8 Other otosclerosis	0.000	0.875	0.125
H80.2 Cochlear otosclerosis	0.000	0.875	0.125
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.875	0.125
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.875	0.125
T50.7 Analeptics and opioid receptor antagonists	0.125	0.875	0.000
T50.5 Appetite depressants	0.125	0.875	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.125	0.875	0.000
T50.0 Mineralocorticoids and their antagonists	0.125	0.875	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.876	0.124
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.876	0.124
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.119	0.881	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.882	0.118
T50.8 Diagnostic agents	0.117	0.883	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.116	0.883	0.000
J34.3 Hypertrophy of nasal turbinates	0.000	0.885	0.115
H61 Other disorders of external ear	0.000	0.886	0.114
H90.2 Conductive hearing loss, unspecified	0.000	0.886	0.114
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.890	0.110
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.109	0.890	0.001
H91 Other hearing loss	0.000	0.891	0.109
T45.9 Primarily systemic and haematological agent, unspecified	0.108	0.892	0.000
T45.8 Other primarily systemic and haematological agents	0.108	0.892	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.108	0.892	0.000
T45.6 Fibrinolysis-affecting drugs	0.108	0.892	0.000
T45.4 Iron and its compounds	0.108	0.892	0.000
T45.3 Enzymes, not elsewhere classified	0.108	0.892	0.000
T45.2 Vitamins, not elsewhere classified	0.108	0.892	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.893	0.106
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.893	0.106
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.894	0.106
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.895	0.105
H61.8 Other specified disorders of external ear	0.000	0.897	0.103
H91.8 Other specified hearing loss	0.000	0.898	0.102
H90.0 Conductive hearing loss, bilateral	0.000	0.901	0.099
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.901	0.099
T45.5 Anticoagulants	0.098	0.902	0.000
T43.2 Other and unspecified antidepressants	0.095	0.905	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.907	0.093
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.092	0.908	0.000
I15.8 Other secondary hypertension	0.092	0.908	0.000
I15.2 Hypertension secondary to endocrine disorders	0.092	0.908	0.000
H83 Other diseases of inner ear	0.000	0.910	0.090
T43.6 Psychostimulants with abuse potential	0.089	0.911	0.000
H61.0 Perichondritis of external ear	0.000	0.913	0.087
I15.0 Renovascular hypertension	0.087	0.913	0.000
H92 Otalgia and effusion of ear	0.000	0.914	0.086
T45.0 Antiallergic and antiemetic drugs	0.086	0.914	0.000
T43.9 Psychotropic drug, unspecified	0.086	0.914	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.086	0.914	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.915	0.084
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.915	0.084
H93 Other disorders of ear, not elsewhere classified	0.000	0.915	0.085
I15.9 Seconday hypertension, unspecified	0.083	0.917	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.083	0.917	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.917	0.083
I12.9 Hypertensive renal disease without renal failure	0.082	0.918	0.000
N41.1 Chronic prostatitis	0.082	0.918	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.081	0.918	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.918	0.081
H61.9 Disorder of external ear, unspecified	0.000	0.919	0.081
T45.1 Antineoplastic and immunosuppressive drugs	0.079	0.920	0.000
H91.0 Ototoxic hearing loss	0.000	0.921	0.079
H91.3 Deaf mutism, not elsewhere classified	0.000	0.922	0.078
H91.1 Presbycusis	0.000	0.922	0.078
H81 Disorders of vestibular function	0.000	0.922	0.077
H61.1 Non-infective disorders of pinna	0.000	0.925	0.075
H61.3 Acquired stenosis of external ear canal	0.000	0.926	0.074
H60 Otitis externa	0.000	0.926	0.074
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.929	0.071
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.929	0.071
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.929	0.071
H62.2 Otitis externa in mycoses	0.000	0.929	0.071
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.929	0.071
N41 Inflammatory diseases of prostate	0.071	0.929	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.930	0.070
H91.2 Sudden idiopathic hearing loss	0.000	0.931	0.069
H93.9 Disorder of ear, unspecified	0.000	0.931	0.069
T43.5 Other and unspecified antipsychotics and neuroleptics	0.068	0.931	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.932	0.067
H61.2 Impacted cerumen	0.000	0.933	0.067
N41.0 Acute prostatitis	0.067	0.933	0.000
H92.2 Otorrhagia	0.000	0.933	0.067
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.933	0.066
H83.3 Noise effects on inner ear	0.000	0.935	0.065
H81.0 Meniere's disease	0.000	0.935	0.065
H83.2 Labyrinthine dysfunction	0.000	0.935	0.065
H83.1 Labyrinthine fistula	0.000	0.935	0.065
H60.9 Otitis externa, unspecified	0.000	0.937	0.063
H93.2 Other abnormal auditory perceptions	0.000	0.937	0.063
H93.0 Degenerative and vascular disorders of ear	0.000	0.939	0.061
I12.0 Hypertensive renal disease with renal failure	0.059	0.941	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.059	0.941	0.000
I15.1 Hypertension secondary to other renal disorders	0.056	0.943	0.001
N41.2 Abscess of prostate	0.056	0.944	0.000
H81.4 Vertigo of central origin	0.000	0.944	0.056
H65 Nonsuppurative otitis media	0.000	0.945	0.055
H81.3 Other peripheral vertigo	0.000	0.946	0.054
H81.2 Vestibular neuronitis	0.000	0.946	0.054
H60.2 Malignant otitis externa	0.000	0.946	0.054
H83.8 Other specified diseases of inner ear	0.000	0.946	0.054
H60.3 Other infective otitis externa	0.000	0.947	0.053
H93.3 Disorders of acoustic nerve	0.000	0.947	0.053
N41.8 Other inflammatory diseases of prostate	0.051	0.949	0.000
N41.3 Prostatocystitis	0.051	0.949	0.000
H60.0 Abscess of external ear	0.000	0.949	0.051
H81.8 Other disorders of vestibular function	0.000	0.950	0.050
T43.3 Phenothiazine antipsychotics and neuroleptics	0.049	0.951	0.000
H60.4 Cholesteatoma of external ear	0.000	0.952	0.048
H60.1 Cellulitis of external ear	0.000	0.953	0.046
H92.1 Otorrhoea	0.000	0.954	0.046
H93.1 Tinnitus	0.000	0.954	0.046
H92.0 Otalgia	0.000	0.955	0.045
H60.5 Acute otitis externa, non-infective	0.000	0.956	0.044
H93.8 Other specified disorders of ear	0.000	0.958	0.041
H81.9 Disorder of vestibular function, unspecified	0.000	0.960	0.040
H60.8 Other otitis externa	0.000	0.962	0.038
H65.0 Acute serous otitis media	0.000	0.963	0.037
T50.9 Other and unspecified drugs, medicaments and biological substances	0.036	0.963	0.001
H65.2 Chronic serous otitis media	0.000	0.963	0.037
H65.1 Other acute nonsuppurative otitis media	0.000	0.964	0.036
T43.0 Tricyclic and tetracyclic antidepressants	0.034	0.965	0.000
H83.0 Labyrinthitis	0.000	0.969	0.031
H81.1 Benign paroxysmal vertigo	0.000	0.973	0.027
H65.4 Other chronic nonsuppurative otitis media	0.000	0.977	0.023
H52.0 Hypermetropia	0.023	0.977	0.000
H65.3 Chronic mucoid otitis media	0.000	0.977	0.023
H90.5 Sensorineural hearing loss, unspecified	0.001	0.979	0.020
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.983	0.017
J34 Other disorders of nose and nasal sinuses	0.000	0.985	0.015
J34.2 Deviated nasal septum	0.000	0.987	0.013
M25.76 Osteophyte (Lower leg)	0.000	0.988	0.012
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.991	0.009
N28.1 Cyst of kidney, acquired	0.000	0.991	0.009
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.992	0.008
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.992	0.008
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.992	0.008
R73.9 Hyperglycaemia, unspecified	0.008	0.992	0.000
K83.1 Obstruction of bile duct	0.000	0.993	0.007
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.993	0.007
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.993	0.007
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.993	0.006
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.994	0.006
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.994	0.006
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.994	0.006
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.994	0.006
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.994	0.006
Z90.2 Acquired absence of lung [part of]	0.000	0.994	0.006
I27.2 Other secondary pulmonary hypertension	0.000	0.995	0.005
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.996	0.004
B37.9 Candidiasis, unspecified	0.000	0.996	0.004
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.996	0.004
M24.1 Other articular cartilage disorders	0.000	0.996	0.004
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.996	0.004
R73 Elevated blood glucose level	0.004	0.996	0.000
H91.9 Hearing loss, unspecified	0.000	0.996	0.004
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.996	0.004
D37.5 Rectum	0.000	0.996	0.004
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.996	0.004
K83 Other diseases of biliary tract	0.000	0.996	0.004
T51.9 Alcohol, unspecified	0.004	0.996	0.000
H26.4 After-cataract	0.004	0.996	0.000
K83.0 Cholangitis	0.000	0.996	0.004
R73.0 Abnormal glucose tolerance test	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.996	0.003
H26.9 Cataract, unspecified	0.004	0.996	0.000
T51.0 Ethanol	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.997	0.003
M24.18 Other articular cartilage disorders (Other)	0.000	0.997	0.003
M24.14 Other articular cartilage disorders (Hand)	0.000	0.997	0.003
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.997	0.003
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.997	0.003
H26.2 Complicated cataract	0.003	0.997	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.997	0.003
H26 Other cataract	0.003	0.997	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.997	0.003
T51 Toxic effect of alcohol	0.003	0.997	0.000
K83.3 Fistula of bile duct	0.000	0.997	0.003
K83.5 Biliary cyst	0.000	0.997	0.003
K83.2 Perforation of bile duct	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.003	0.997	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.997	0.003
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
C61 Malignant neoplasm of prostate	0.003	0.997	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.997	0.000
H26.1 Traumatic cataract	0.003	0.997	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.003	0.997	0.000
H26.3 Drug-induced cataract	0.002	0.997	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.997	0.003
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.997	0.002
M05.1 Rheumatoid lung disease	0.000	0.997	0.002
M05.0 Felty's syndrome	0.000	0.997	0.002
T51.8 Other alcohols	0.002	0.997	0.000
T51.3 Fusel oil	0.002	0.997	0.000
T51.2 2-Propanol	0.002	0.997	0.000
T51.1 Methanol	0.002	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
R40.0 Somnolence	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
H26.0 Infantile, juvenile and presenile cataract	0.002	0.998	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.998	0.002
M05.2 Rheumatoid vasculitis	0.000	0.998	0.002
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
I27 Other pulmonary heart diseases	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.000	0.998	0.002
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
L29.0 Pruritus ani	0.000	0.998	0.002
O90 Complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.998	0.002
M05.08 Felty's syndrome (Other)	0.000	0.998	0.002
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.998	0.002
M05.06 Felty's syndrome (Lower leg)	0.000	0.998	0.002
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.998	0.002
M05.04 Felty's syndrome (Hand)	0.000	0.998	0.002
M05.03 Felty's syndrome (Forearm)	0.000	0.998	0.002
M05.02 Felty's syndrome (Upper arm)	0.000	0.998	0.002
M05.01 Felty's syndrome (Shoulder region)	0.000	0.998	0.002
M05.00 Felty's syndrome (Multiple sites)	0.000	0.998	0.002
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.998	0.002
M05.18 Rheumatoid lung disease (Other)	0.000	0.998	0.002
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.998	0.002
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.998	0.002
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.998	0.002
M05.14 Rheumatoid lung disease (Hand)	0.000	0.998	0.002
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.998	0.002
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.998	0.002
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.998	0.002
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.998	0.002
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.998	0.002
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.998	0.002
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.998	0.002
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.998	0.002
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.998	0.002
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.998	0.002
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.998	0.002
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.998	0.002
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.998	0.002
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.998	0.002
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.998	0.002
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.000	0.998	0.002
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.998	0.002
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.998	0.002
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
M05.28 Rheumatoid vasculitis (Other)	0.000	0.998	0.002
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.998	0.002
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.998	0.002
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.998	0.002
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.998	0.002
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.998	0.002
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.998	0.002
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.998	0.002
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.998	0.002
G44.2 Tension-type headache	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
O90.9 Complication of the puerperium, unspecified	0.000	0.998	0.002
O90.1 Disruption of perineal obstetric wound	0.000	0.998	0.002
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
O90.2 Haematoma of obstetric wound	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.998	0.002
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
Q85.9 Phakomatosis, unspecified	0.000	0.998	0.002
H52.6 Other disorders of refraction	0.002	0.998	0.000
H52.5 Disorders of accommodation	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
L29 Pruritus	0.000	0.998	0.002
H52.7 Disorder of refraction, unspecified	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.000	0.998	0.002
O90.4 Postpartum acute renal failure	0.000	0.998	0.002
O90.3 Cardiomyopathy in the puerperium	0.000	0.998	0.002
O90.0 Disruption of Caesarean section wound	0.000	0.998	0.002
H52.4 Presbyopia	0.002	0.998	0.000
C60.1 Glans penis	0.002	0.998	0.000
L89.2 Stage III decubitus ulcer	0.002	0.998	0.000
C60 Malignant neoplasm of penis	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
N85.4 Malposition of uterus	0.000	0.998	0.002
L29.2 Pruritus vulvae	0.000	0.998	0.002
J13 Pneumonia due to Streptococcus pneumoniae	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.002	0.998	0.000
C60.9 Penis, unspecified	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.000	0.998	0.002
N42.8 Other specified disorders of prostate	0.002	0.998	0.000
C60.0 Prepuce	0.001	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.001
L29.1 Pruritus scroti	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations