TreeWAS – Variant ID: rs11118883

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.054	0.946	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.967	0.033
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.972	0.028
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.979	0.021
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.985	0.015
C18.2 Ascending colon	0.014	0.986	0.000
I34.1 Mitral (valve) prolapse	0.000	0.986	0.014
C18.4 Transverse colon	0.013	0.987	0.000
C18 Malignant neoplasm of colon	0.013	0.987	0.000
C18.0 Caecum	0.013	0.987	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.012	0.988	0.000
C18.5 Splenic flexure	0.011	0.989	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.989	0.011
C18.1 Appendix	0.011	0.989	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.989	0.011
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.990	0.010
M47.8 Other spondylosis	0.000	0.990	0.010
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.990	0.010
M47.82 Other spondylosis (Cervical region)	0.000	0.991	0.009
C18.8 Overlapping lesion of colon	0.009	0.991	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.009	0.991	0.000
M47.84 Other spondylosis (Thoracic region)	0.000	0.991	0.009
M47.89 Other spondylosis (Site unspecified)	0.000	0.992	0.008
C18.7 Sigmoid colon	0.008	0.992	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.992	0.008
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.992	0.008
S72.40 Fracture of lower end of femur (closed)	0.008	0.992	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.992	0.008
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.992	0.008
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.008	0.992	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.008	0.992	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.008	0.992	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.993	0.007
C18.6 Descending colon	0.007	0.993	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.993	0.007
R06.4 Hyperventilation	0.000	0.993	0.007
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.993	0.007
C18.9 Colon, unspecified	0.007	0.993	0.000
K42 Umbilical hernia	0.000	0.994	0.006
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.006	0.994	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.994	0.006
C18.3 Hepatic flexure	0.005	0.994	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.994	0.005
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.006	0.994	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.994	0.005
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.995	0.005
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.995	0.005
S72.4 Fracture of lower end of femur	0.005	0.995	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.995	0.005
K42.1 Umbilical hernia with gangrene	0.000	0.995	0.005
Y79 Orthopaedic devices associated with adverse incidents	0.005	0.995	0.000
Z29.2 Other prophylactic chemotherapy	0.005	0.995	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.005	0.995	0.000
S22.20 Fracture of sternum (closed)	0.004	0.996	0.000
H91.9 Hearing loss, unspecified	0.004	0.996	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.004	0.996	0.000
M34.1 CR(E)ST syndrome	0.004	0.996	0.000
R19.5 Other fecal abnormalities	0.000	0.996	0.004
T86 Failure and rejection of transplanted organs and tissues	0.004	0.996	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
M34.9 Systemic sclerosis, unspecified	0.004	0.996	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.004	0.996	0.000
T86.4 Liver transplant failure and rejection	0.004	0.996	0.000
M34 Systemic sclerosis	0.004	0.996	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.996	0.004
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.996	0.004
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.996	0.004
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.996	0.004
Y79.8 Miscellaneous devices, not elsewhere classified	0.003	0.996	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.003	0.996	0.000
Y79.0 Diagnostic and monitoring devices	0.003	0.996	0.000
M34.0 Progressive systemic sclerosis	0.003	0.996	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.003	0.997	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.997	0.003
F31 Bipolar affective disorder	0.000	0.997	0.003
S72 Fracture of femur	0.003	0.997	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.003	0.997	0.000
T86.3 Heart-lung transplant failure and rejection	0.003	0.997	0.000
T86.2 Heart transplant failure and rejection	0.003	0.997	0.000
S72.41 Fracture of lower end of femur (open)	0.003	0.997	0.000
S72.3 Fracture of shaft of femur	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.997	0.003
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.997	0.003
M34.2 Systemic sclerosis induced by drugs and chemicals	0.003	0.997	0.000
S70.1 Contusion of thigh	0.003	0.997	0.000
S70-S79 Injuries to the hip and thigh	0.003	0.997	0.000
F52.2 Failure of genital response	0.000	0.997	0.003
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
S70.7 Multiple superficial injuries of hip and thigh	0.003	0.997	0.000
S70.0 Contusion of hip	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
S79.9 Unspecified injury of hip and thigh	0.003	0.997	0.000
T86.0 Bone-marrow transplant rejection	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
S72.31 Fracture of shaft of femur (open)	0.003	0.997	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
N85.0 Endometrial glandular hyperplasia	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.997	0.003
S72.7 Multiple fractures of femur	0.002	0.997	0.000
S71 Open wound of hip and thigh	0.003	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
O41.0 Oligohydramnios	0.000	0.998	0.002
S71.1 Open wound of thigh	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
K76.8 Other specified diseases of liver	0.000	0.998	0.002
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
H91 Other hearing loss	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S79.7 Multiple injuries of hip and thigh	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.000	0.998	0.002
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
S73.1 Sprain and strain of hip	0.002	0.998	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.002	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.002	0.998	0.000
S72.70 Multiple fractures of femur (closed)	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.002	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.002	0.998	0.000
S73.0 Dislocation of hip	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.002	0.998	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.998	0.002
S72.0 Fracture of neck of femur	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.998	0.002
S22.2 Fracture of sternum	0.002	0.998	0.000
T86.1 Kidney transplant failure and rejection	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
M47 Spondylosis	0.000	0.998	0.002
S72.81 Fractures of other parts of femur (open)	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
S71.0 Open wound of hip	0.002	0.998	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.002	0.998	0.000
S74.8 Injury of other nerves at hip and thigh level	0.002	0.998	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.002	0.998	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.002	0.998	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.002	0.998	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.002	0.998	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.002	0.998	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.002	0.998	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.002	0.998	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.002	0.998	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.002	0.998	0.000
S75.0 Injury of femoral artery	0.002	0.998	0.000
S77.2 Crushing injury of hip with thigh	0.002	0.998	0.000
S77.1 Crushing injury of thigh	0.002	0.998	0.000
S77.0 Crushing injury of hip	0.002	0.998	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.002	0.998	0.000
S78.1 Traumatic amputation at level between hip and knee	0.002	0.998	0.000
S78.0 Traumatic amputation at hip joint	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.002	0.998	0.000
S72.91 Fracture of femur, part unspecified (open)	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
T87.6 Other and unspecified complications of amputation stump	0.000	0.998	0.002
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
Z50.2 Alcohol rehabilitation	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.998	0.002
K62.3 Rectal prolapse	0.000	0.998	0.002
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.998	0.002
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.998	0.002
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.998	0.002
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.998	0.002
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.998	0.002
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.998	0.002
S72.80 Fractures of other parts of femur (closed)	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
M70.6 Trochanteric bursitis	0.000	0.998	0.002
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
S76.1 Injury of quadriceps muscle and tendon	0.001	0.998	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.001	0.998	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.001	0.998	0.000
S76.0 Injury of muscle and tendon of hip	0.001	0.998	0.000
W50.8 Other specified place	0.002	0.998	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.998	0.002
Y81 General- and plastic-surgery devices associated with adverse incidents	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
L27.0 Generalised skin eruption due to drugs and medicaments	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
O02 Other abnormal products of conception	0.002	0.998	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
Y80 Physical medicine devices associated with adverse incidents	0.002	0.998	0.000
Y78 Radiological devices associated with adverse incidents	0.002	0.998	0.000
Y75 Neurological devices associated with adverse incidents	0.002	0.998	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.002	0.998	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.002	0.998	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.002	0.998	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.001	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
R01.0 Benign and innocent cardiac murmurs	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.998	0.002
Y73.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.001	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.001	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
F52.0 Lack or loss of sexual desire	0.000	0.998	0.001
Y71 Cardiovascular devices associated with adverse incidents	0.001	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
R73 Elevated blood glucose level	0.000	0.998	0.002
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.001
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.001
F52.7 Excessive sexual drive	0.000	0.998	0.001
F52.6 Nonorganic dyspareunia	0.000	0.998	0.001
F52.5 Nonorganic vaginismus	0.000	0.998	0.001
F52.4 Premature ejaculation	0.000	0.998	0.001
F52.3 Orgasmic dysfunction	0.000	0.998	0.001
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.001
R68.0 Hypothermia, not associated with low environmental temperature	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
M70.69 Trochanteric bursitis-Site unspec	0.000	0.998	0.001
M70.68 Trochanteric bursitis-Other	0.000	0.998	0.001
M70.67 Trochanteric bursitis-Ankle/Foot	0.000	0.998	0.001
M70.66 Trochanteric bursitis-Lower Leg	0.000	0.998	0.001
M70.64 Trochanteric bursitis-Hand	0.000	0.998	0.001
M70.63 Trochanteric bursitis-Forearm	0.000	0.998	0.001
M70.62 Trochanteric bursitis-Upper arm	0.000	0.998	0.001
M70.61 Trochanteric bursitis-Shldr region	0.000	0.998	0.001
M70.60 Trochanteric bursitis-Mult sites	0.000	0.998	0.001
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
H93.3 Disorders of acoustic nerve	0.001	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.998	0.002
T87.4 Infection of amputation stump	0.000	0.998	0.002
Y73.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y73.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y73.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y73.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y81.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
S72.11 Pertrochanteric fracture (open)	0.001	0.998	0.000
D12.6 Colon, unspecified	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.001	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.998	0.001
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.998	0.001
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.998	0.001
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.998	0.001
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.998	0.001
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.998	0.001
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.998	0.001
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.998	0.001
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.000	0.998	0.001
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.001	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.998	0.000
H93.8 Other specified disorders of ear	0.001	0.998	0.000
K04.8 Radicular cyst	0.002	0.998	0.000
Y81.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y81.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y81.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y81.0 Diagnostic and monitoring devices	0.001	0.998	0.000
H91.1 Presbycusis	0.001	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.001	0.998	0.000
O02.8 Other specified abnormal products of conception	0.001	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.998	0.001
R60.9 Oedema, unspecified	0.002	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.998	0.001
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.998	0.001
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.998	0.001
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.998	0.001
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.001	0.998	0.000
Y70.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y70.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y70.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y70.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y70.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y72.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y72.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y72.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y72.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y72.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y74.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y74.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y74.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y74.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y74.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y75.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y75.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y75.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y75.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y75.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y77.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y77.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y78.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y78.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y78.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y78.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y78.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y80.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y80.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y80.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y80.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y80.0 Diagnostic and monitoring devices	0.001	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.001	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.999	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.999	0.000
D58.2 Other haemoglobinopathies	0.001	0.999	0.000
D58.1 Hereditary elliptocytosis	0.001	0.999	0.000
O04.4 Incomplete, without complication	0.000	0.999	0.001
Y71.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.001	0.999	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.999	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
Y82.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y82.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y82.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y82.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y71.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y71.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y71.0 Diagnostic and monitoring devices	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
W50.2 School, other institution and public administrative area	0.001	0.999	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.999	0.000
H93.9 Disorder of ear, unspecified	0.001	0.999	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.999	0.000
W50.9 Unspecified place	0.001	0.999	0.000
Z98.0 Intestinal bypass and anastomosis status	0.001	0.999	0.000
H90 Conductive and sensorineural hearing loss	0.001	0.999	0.000
I70 Atherosclerosis	0.000	0.999	0.001
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.999	0.001
I70.1 Atherosclerosis of renal artery	0.000	0.999	0.001
Y76.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y76.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y82.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Z01.7 Laboratory examination	0.000	0.999	0.001
H94 Other disorders of ear in diseases classified elsewhere	0.001	0.999	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.999	0.001
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.001	0.999	0.000
N76.0 Acute vaginitis	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.999	0.001
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.001	0.999	0.000
I87.1 Compression of vein	0.000	0.999	0.001
N64.9 Disorder of breast, unspecified	0.000	0.999	0.001
W64.9 Unspecified place	0.001	0.999	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.999	0.001
D48.5 Skin	0.001	0.999	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.999	0.001
T25.2 Burn of second degree of ankle and foot	0.001	0.999	0.000
W50.3 Sports and athletics area	0.001	0.999	0.000
W50.7 Farm	0.001	0.999	0.000
W50.6 Industrial and construction area	0.001	0.999	0.000
W50.5 Trade and service area	0.001	0.999	0.000
W50.4 Street and highway	0.001	0.999	0.000
W50.1 Residential institution	0.001	0.999	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
H18.0 Corneal pigmentations and deposits	0.000	0.999	0.001
I22.9 Subsequent myocardial infarction of unspecified site	0.001	0.999	0.000
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
T87.3 Neuroma of amputation stump	0.000	0.999	0.001
W50.0 Home	0.001	0.999	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
Y71.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.999	0.001
M10.92 Gout, unspecified (Upper arm)	0.000	0.999	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.001	0.999	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.999	0.001
I70.8 Atherosclerosis of other arteries	0.000	0.999	0.001
N42.0 Calculus of prostate	0.000	0.999	0.001
H18 Other disorders of cornea	0.000	0.999	0.001
S97 Crushing injury of ankle and foot	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.999	0.000
F40.0 Agoraphobia	0.001	0.999	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.999	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I70.0 Atherosclerosis of aorta	0.000	0.999	0.001
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.999	0.001
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
Z89.6 Acquired absence of leg above knee	0.000	0.999	0.001
N23 Unspecified renal colic	0.000	0.999	0.001
M10.93 Gout, unspecified (Forearm)	0.000	0.999	0.001
S52.70 Multiple fractures of forearm (closed)	0.000	0.999	0.001
S72.00 Fracture of neck of femur (closed)	0.001	0.999	0.000
D48.1 Connective and other soft tissue	0.000	0.999	0.001
F02.3 Dementia in Parkinson's disease	0.000	0.999	0.001
J35.1 Hypertrophy of tonsils	0.001	0.999	0.000
K00.6 Disturbances in tooth eruption	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
T87.5 Necrosis of amputation stump	0.000	0.999	0.001
T87.2 Complications of other reattached body part	0.000	0.999	0.001
T87.1 Complications of reattached (part of) lower extremity	0.000	0.999	0.001
T87.0 Complications of reattached (part of) upper extremity	0.000	0.999	0.001
Z22.3 Carrier of other specified bacterial diseases	0.000	0.999	0.001
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.999	0.001
W50.30 Hit, struck, kicked, twisted, bitten or scratched by another person; Sports and athletics area;While engaged in sports activity	0.001	0.999	0.000
H18.3 Changes in corneal membranes	0.000	0.999	0.001
T25.3 Burn of third degree of ankle and foot	0.001	0.999	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.999	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.999	0.001
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.999	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.999	0.001
T25 Burn and corrosion of ankle and foot	0.001	0.999	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.999	0.001
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.999	0.001
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.999	0.001
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.999	0.001
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.999	0.001
H18.7 Other corneal deformities	0.000	0.999	0.001
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.999	0.000
Z56.0 Unemployment, unspecified	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
Z35 Supervision of high-risk pregnancy	0.001	0.999	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.000
G72.9 Myopathy, unspecified	0.001	0.999	0.000
H18.6 Keratoconus	0.000	0.999	0.001
H95.1 Other disorders following mastoidectomy	0.001	0.999	0.000
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.999	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.999	0.001
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
M91.15 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Pelv	0.001	0.999	0.000
H15.1 Episcleritis	0.000	0.999	0.001
H18.1 Bullous keratopathy	0.000	0.999	0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
H90.3 Sensorineural hearing loss, bilateral	0.001	0.999	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.001	0.999	0.000
Z35.5 Supervision of elderly primigravida	0.001	0.999	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations