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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1112839
log Bayes Factor = 12.8791
Chromosome 1   position 169,351,819  (GRCh37) Explore rs1112839 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D68.2 Hereditary deficiency of other clotting factors
1.000 0.000 0.000
D68 Other coagulation defects
0.861 0.139 0.000
D68.5 Primary Thrombophilia
0.856 0.144 0.000
D68.6 Other Thrombophilia
0.675 0.325 0.000
D68.8 Other specified coagulation defects
0.641 0.359 0.000
D68.1 Hereditary factor XI deficiency
0.588 0.412 0.000
D68.4 Acquired coagulation factor deficiency
0.534 0.465 0.000
D68.0 Von Willebrand's disease
0.513 0.487 0.000
D68.9 Coagulation defect, unspecified
0.455 0.545 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.320 0.680 0.001
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.172 0.828 0.000
I80 Phlebitis and thrombophlebitis
0.142 0.858 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.140 0.860 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.129 0.871 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.121 0.879 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.113 0.887 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.109 0.891 0.000
D67 Hereditary factor IX deficiency
0.096 0.904 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.084 0.916 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.081 0.918 0.000
Z91.5 Personal history of self-harm
0.067 0.933 0.000
D66 Hereditary factor VIII deficiency
0.065 0.934 0.000
D69 Purpura and other haemorrhagic conditions
0.064 0.936 0.000
D69.5 Secondary thrombocytopenia
0.060 0.940 0.000
D69.8 Other specified haemorrhagic conditions
0.054 0.946 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.052 0.948 0.000
D69.0 Allergic purpura
0.050 0.950 0.000
D69.2 Other nonthrombocytopenic purpura
0.049 0.951 0.000
D75 Other diseases of blood and blood-forming organs
0.049 0.951 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.048 0.952 0.000
D75.1 Secondary polycythaemia
0.047 0.953 0.000
F32.0 Mild depressive episode
0.047 0.953 0.000
D80-D89 Certain disorders involving the immune mechanism
0.045 0.955 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.044 0.956 0.000
F32 Depressive episode
0.044 0.956 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.043 0.957 0.000
D69.9 Haemorrhagic condition, unspecified
0.042 0.958 0.000
D69.1 Qualitative platelet defects
0.042 0.958 0.000
D86 Sarcoidosis
0.041 0.959 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.041 0.959 0.000
F32.9 Depressive episode, unspecified
0.040 0.960 0.000
D75.2 Essential thrombocytosis
0.040 0.960 0.000
D80 Immunodeficiency with predominantly antibody defects
0.038 0.962 0.000
D86.8 Sarcoidosis of other and combined sites
0.037 0.963 0.000
D86.9 Sarcoidosis, unspecified
0.037 0.963 0.000
D76.3 Other histiocytosis syndromes
0.036 0.964 0.000
D73 Diseases of spleen
0.036 0.964 0.000
D86.0 Sarcoidosis of lung
0.035 0.965 0.000
D75.0 Familial erythrocytosis
0.035 0.965 0.000
D74 Methaemoglobinaemia
0.034 0.965 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.034 0.965 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.034 0.965 0.000
F32.1 Moderate depressive episode
0.033 0.967 0.000
D83 Common variable immunodeficiency
0.033 0.967 0.000
D81 Combined immunodeficiencies
0.032 0.968 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.032 0.968 0.000
D82 Immunodeficiency associated with other major defects
0.032 0.968 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.032 0.968 0.000
F32.8 Other depressive episodes
0.031 0.969 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.030 0.970 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.030 0.970 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.030 0.970 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.030 0.970 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.030 0.970 0.000
D84 Other immunodeficiencies
0.030 0.970 0.000
D73.1 Hypersplenism
0.029 0.970 0.000
D69.4 Other primary thrombocytopenia
0.029 0.971 0.000
D73.0 Hyposplenism
0.029 0.971 0.000
D60-D64 Aplastic and other anaemias
0.028 0.972 0.000
D73.4 Cyst of spleen
0.027 0.972 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.027 0.973 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.027 0.973 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.027 0.973 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.027 0.973 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.027 0.973 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.027 0.973 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.027 0.973 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.026 0.973 0.000
D73.9 Disease of spleen, unspecified
0.026 0.974 0.000
D73.2 Chronic congestive splenomegaly
0.026 0.974 0.000
D55-D59 Haemolytic anaemias
0.026 0.974 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.026 0.974 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.026 0.974 0.000
D74.9 Methaemoglobinaemia, unspecified
0.025 0.975 0.000
D74.8 Other methaemoglobinaemias
0.025 0.975 0.000
D74.0 Congenital methaemoglobinaemia
0.025 0.975 0.000
D73.5 Infarction of spleen
0.025 0.975 0.000
D83.9 Common variable immunodeficiency, unspecified
0.024 0.976 0.000
D73.3 Abscess of spleen
0.024 0.976 0.000
D83.8 Other common variable immunodeficiencies
0.023 0.976 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.023 0.976 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.023 0.976 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.023 0.976 0.000
D81.9 Combined immunodeficiency, unspecified
0.023 0.976 0.000
D81.8 Other combined immunodeficiencies
0.023 0.976 0.000
D81.7 Major histocompatibility complex class II deficiency
0.023 0.976 0.000
D81.6 Major histocompatibility complex class I deficiency
0.023 0.976 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.023 0.976 0.000
D81.4 Nezelof's syndrome
0.023 0.976 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.023 0.976 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.023 0.976 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.023 0.976 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.023 0.976 0.000
D84.8 Other specified immunodeficiencies
0.023 0.977 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.023 0.977 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.023 0.977 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.023 0.977 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.023 0.977 0.000
D82.2 Immunodeficiency with short-limbed stature
0.023 0.977 0.000
D82.0 Wiskott-Aldrich syndrome
0.023 0.977 0.000
D86.3 Sarcoidosis of skin
0.023 0.977 0.000
D73.8 Other diseases of spleen
0.023 0.977 0.000
D82.1 Di George's syndrome
0.022 0.977 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.022 0.978 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.022 0.978 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.022 0.978 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.021 0.978 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.021 0.978 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.021 0.979 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.021 0.979 0.000
D72 Other disorders of white blood cells
0.021 0.979 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.021 0.979 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.020 0.980 0.000
T36 Poisoning by systemic antibiotics
0.020 0.980 0.000
T45.2 Vitamins, not elsewhere classified
0.020 0.980 0.000
D84.1 Defects in the complement system
0.019 0.981 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.019 0.981 0.000
D57 Sickle-cell disorders
0.019 0.981 0.000
D55 Anaemia due to enzyme disorders
0.019 0.981 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.019 0.981 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.019 0.981 0.000
D84.9 Immunodeficiency, unspecified
0.018 0.981 0.000
T45.0 Antiallergic and antiemetic drugs
0.019 0.981 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.018 0.982 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.018 0.982 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.018 0.982 0.000
T42.1 Iminostilbenes
0.018 0.982 0.000
T42.4 Benzodiazepines
0.018 0.982 0.000
D59 Acquired haemolytic anaemia
0.018 0.982 0.000
D64 Other anaemias
0.018 0.982 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.017 0.983 0.000
T45.5 Anticoagulants
0.017 0.983 0.000
D56 Thalassaemia
0.017 0.983 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.017 0.983 0.000
T42.0 Hydantoin derivatives
0.017 0.983 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.016 0.983 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.016 0.983 0.000
T36.4 Tetracyclines
0.016 0.984 0.000
D89.1 Cryoglobulinaemia
0.016 0.984 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.016 0.984 0.000
T36.8 Other systemic antibiotics
0.016 0.984 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.016 0.984 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.016 0.984 0.000
T42.3 Barbiturates
0.016 0.984 0.000
T42.2 Succinimides and oxazolidinediones
0.016 0.984 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.016 0.984 0.000
T45.8 Other primarily systemic and haematological agents
0.016 0.984 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.016 0.984 0.000
T45.6 Fibrinolysis-affecting drugs
0.016 0.984 0.000
T45.4 Iron and its compounds
0.016 0.984 0.000
T45.3 Enzymes, not elsewhere classified
0.016 0.984 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.016 0.984 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.016 0.984 0.000
T36.3 Macrolides
0.016 0.984 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.016 0.984 0.000
T36.0 Penicillins
0.016 0.984 0.000
D89.3 Immune reconstitution syndrome
0.015 0.984 0.000
D86.1 Sarcoidosis of lymph nodes
0.015 0.984 0.001
D60.9 Acquired pure red cell aplasia, unspecified
0.015 0.984 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.015 0.984 0.000
Z45.2 Adjustment and management of vascular access device
0.015 0.985 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.015 0.985 0.000
D72.9 Disorder of white blood cells, unspecified
0.015 0.985 0.000
D72.0 Genetic anomalies of leukocytes
0.015 0.985 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.015 0.985 0.000
Y40.0 Penicillins
0.015 0.985 0.000
D60.8 Other acquired pure red cell aplasias
0.015 0.985 0.000
D60.1 Transient acquired pure red cell aplasia
0.015 0.985 0.000
D60.0 Chronic acquired pure red cell aplasia
0.015 0.985 0.000
D64.8 Other specified anaemias
0.015 0.985 0.000
D50-D53 Nutritional anaemias
0.015 0.985 0.000
T36.9 Systemic antibiotic, unspecified
0.015 0.985 0.000
T36.7 Antifungal antibiotics, systemically used
0.015 0.985 0.000
T36.6 Rifamycins
0.015 0.985 0.000
T36.5 Aminoglycosides
0.015 0.985 0.000
T36.2 Chloramphenicol group
0.015 0.985 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.015 0.985 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.015 0.985 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.015 0.985 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.015 0.985 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.015 0.985 0.000
T44.0 Anticholinesterase agents
0.015 0.985 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.015 0.985 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.015 0.985 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.015 0.985 0.000
T43.6 Psychostimulants with abuse potential
0.015 0.985 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.014 0.986 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.014 0.986 0.000
D58 Other hereditary haemolytic anaemias
0.014 0.986 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.014 0.986 0.000
D64.0 Hereditary sideroblastic anaemia
0.014 0.986 0.000
D55.9 Anaemia due to enzyme disorder, unspecified
0.014 0.986 0.000
D55.8 Other anaemias due to enzyme disorders
0.014 0.986 0.000
D55.3 Anaemia due to disorders of nucleotide metabolism
0.014 0.986 0.000
D55.2 Anaemia due to disorders of glycolytic enzymes
0.014 0.986 0.000
D55.1 Anaemia due to other disorders of glutathione metabolism
0.014 0.986 0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.014 0.986 0.000
D57.8 Other sickle-cell disorders
0.014 0.986 0.000
D57.3 Sickle-cell trait
0.014 0.986 0.000
D57.2 Double heterozygous sickling disorders
0.014 0.986 0.000
D57.1 Sickle-cell anaemia without crisis
0.014 0.986 0.000
D57.0 Sickle-cell anaemia with crisis
0.014 0.986 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.014 0.986 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.014 0.986 0.000
T43.9 Psychotropic drug, unspecified
0.014 0.986 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.014 0.986 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.013 0.987 0.000
D59.8 Other acquired haemolytic anaemias
0.013 0.987 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.013 0.987 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.013 0.987 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.013 0.987 0.000
D59.3 Haemolytic-uraemic syndrome
0.013 0.987 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.013 0.987 0.000
D64.4 Congenital dyserythropoietic anaemia
0.013 0.987 0.000
D64.3 Other sideroblastic anaemias
0.013 0.987 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.013 0.987 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.013 0.987 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.013 0.987 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.012 0.988 0.000
D56.9 Thalassaemia, unspecified
0.012 0.988 0.000
D56.8 Other thalassaemias
0.012 0.988 0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.012 0.988 0.000
D56.2 Delta-beta thalassaemia
0.012 0.988 0.000
D56.0 Alpha thalassaemia
0.012 0.988 0.000
T46.1 Calcium-channel blockers
0.012 0.988 0.000
T49.9 Topical agent, unspecified
0.012 0.988 0.000
T49.8 Other topical agents
0.012 0.988 0.000
T49.7 Dental drugs, topically applied
0.012 0.988 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.012 0.988 0.000
T49.5 Ophthalmological drugs and preparations
0.012 0.988 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.012 0.988 0.000
T49.3 Emollients, demulcents and protectants
0.012 0.988 0.000
T49.2 Local astringents and local detergents
0.012 0.988 0.000
T49.1 Antipruritics
0.012 0.988 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.012 0.988 0.000
T50.8 Diagnostic agents
0.012 0.988 0.000
D53 Other nutritional anaemias
0.012 0.988 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.012 0.988 0.000
D56.3 Thalassaemia trait
0.012 0.988 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.012 0.988 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.012 0.988 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.012 0.988 0.000
T46.7 Peripheral vasodilators
0.012 0.988 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.012 0.988 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.012 0.988 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.012 0.988 0.000
T48.5 Anti-common-cold drugs
0.012 0.988 0.000
T48.4 Expectorants
0.012 0.988 0.000
T48.3 Antitussives
0.012 0.988 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.012 0.988 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.012 0.988 0.000
T48.0 Oxytocic drugs
0.012 0.988 0.000
D72.1 Eosinophilia
0.012 0.988 0.000
T41.5 Therapeutic gases
0.011 0.988 0.000
T41.4 Anaesthetic, unspecified
0.011 0.988 0.000
T41.3 Local anaesthetics
0.011 0.988 0.000
T41.2 Other and unspecified general anaesthetics
0.011 0.988 0.000
T41.1 Intravenous anaesthetics
0.011 0.988 0.000
T41.0 Inhaled anaesthetics
0.011 0.988 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.012 0.988 0.000
I82 Other venous embolism and thrombosis
0.011 0.989 0.000
D63.0 Anaemia in neoplastic disease
0.011 0.989 0.000
T50.4 Drugs affecting uric acid metabolism
0.011 0.989 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.011 0.989 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.011 0.989 0.000
D59.1 Other autoimmune haemolytic anaemias
0.011 0.989 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.011 0.989 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.011 0.989 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.011 0.989 0.000
T47.7 Emetics
0.011 0.989 0.000
T47.6 Antidiarrhoeal drugs
0.011 0.989 0.000
T47.5 Digestants
0.011 0.989 0.000
T47.4 Other laxatives
0.011 0.989 0.000
T47.3 Saline and osmotic laxatives
0.011 0.989 0.000
T47.2 Stimulant laxatives
0.011 0.989 0.000
T50.7 Analeptics and opioid receptor antagonists
0.011 0.989 0.000
T50.5 Appetite depressants
0.011 0.989 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.011 0.989 0.000
T50.1 Loop [high-ceiling] diuretics
0.011 0.989 0.000
T50.0 Mineralocorticoids and their antagonists
0.011 0.989 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.011 0.989 0.000
T40.3 Methadone
0.011 0.989 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.011 0.989 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.011 0.989 0.000
I82.8 Embolism and thrombosis of other specified veins
0.011 0.989 0.000
T47.0 Histamine H(2)-receptor antagonists
0.010 0.989 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.010 0.989 0.000
D58.2 Other haemoglobinopathies
0.010 0.989 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.010 0.989 0.000
T37.5 Antiviral drugs
0.010 0.989 0.000
T37.4 Anthelminthics
0.010 0.989 0.000
T37.3 Other antiprotozoal drugs
0.010 0.989 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.010 0.989 0.000
T37.1 Antimycobacterial drugs
0.010 0.989 0.000
T37.0 Sulphonamides
0.010 0.989 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.011 0.989 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.010 0.989 0.000
D58.1 Hereditary elliptocytosis
0.010 0.989 0.000
D56.1 Beta thalassaemia
0.010 0.990 0.000
T43.2 Other and unspecified antidepressants
0.010 0.990 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.010 0.990 0.000
T40.1 Heroin
0.010 0.990 0.000
I86 Varicose veins of other sites
0.010 0.990 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.010 0.990 0.000
T40.8 Lysergide [LSD]
0.010 0.990 0.000
T40.7 Cannabis (derivatives)
0.010 0.990 0.000
T40.0 Opium
0.010 0.990 0.000
I82.0 Budd-Chiari syndrome
0.010 0.990 0.000
M07.3 Other psoriatic arthropathies
0.010 0.990 0.000
Y40 Systemic antibiotics
0.010 0.990 0.000
Y40.8 Other systemic antibiotics
0.009 0.990 0.000
D61 Other aplastic anaemias
0.009 0.991 0.001
D53.9 Nutritional anaemia, unspecified
0.009 0.991 0.000
T40.4 Other synthetic narcotics
0.009 0.991 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.009 0.991 0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.009 0.991 0.000
T40.5 Cocaine
0.009 0.991 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.009 0.991 0.000
I86.2 Pelvic varices
0.009 0.991 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.009 0.991 0.000
T40.2 Other opioids
0.009 0.991 0.000
D51 Vitamin B12 deficiency anaemia
0.009 0.991 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.009 0.991 0.000
D53.8 Other specified nutritional anaemias
0.009 0.991 0.000
D53.2 Scorbutic anaemia
0.009 0.991 0.000
D53.0 Protein deficiency anaemia
0.009 0.991 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.009 0.991 0.000
F30-F39 Mood [affective] disorders
0.009 0.991 0.000
I86.4 Gastric varices
0.009 0.991 0.000
D58.0 Hereditary spherocytosis
0.008 0.991 0.000
I87 Other disorders of veins
0.009 0.991 0.000
D72.8 Other specified disorders of white blood cells
0.009 0.991 0.000
T40.6 Other and unspecified narcotics
0.009 0.991 0.000
D62 Acute posthaemorrhagic anaemia
0.009 0.991 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.009 0.991 0.000
I82.1 Thrombophlebitis migrans
0.008 0.992 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.008 0.992 0.000
M07 Psoriatic and enteropathic arthropathies
0.008 0.992 0.000
M05 Seropositive rheumatoid arthritis
0.008 0.992 0.000
T38.9 Other and unspecified hormone antagonists
0.008 0.992 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.008 0.992 0.000
T38.7 Androgens and anabolic congeners
0.008 0.992 0.000
T38.5 Other oestrogens and progestogens
0.008 0.992 0.000
T38.4 Oral contraceptives
0.008 0.992 0.000
T38.2 Antithyroid drugs
0.008 0.992 0.000
T38.0 Glucocorticoids and synthetic analogues
0.008 0.992 0.000
I86.3 Vulval varices
0.008 0.992 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.008 0.992 0.000
I82.3 Embolism and thrombosis of renal vein
0.008 0.992 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.008 0.992 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.008 0.992 0.000
I88 Nonspecific lymphadenitis
0.008 0.992 0.000
L05.9 Pilonidal cyst without abscess
0.000 0.992 0.008
D52 Folate deficiency anaemia
0.007 0.992 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.007 0.992 0.000
I86.0 Sublingual varices
0.007 0.992 0.000
Y40.5 Aminoglycosides
0.007 0.992 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.007 0.993 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.007 0.993 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.007 0.993 0.000
I86.8 Varicose veins of other specified sites
0.007 0.993 0.000
M05-M14 Inflammatory polyarthropathies
0.007 0.993 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.007 0.993 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.007 0.993 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.007 0.993 0.000
Y40.6 Rifamycins
0.007 0.993 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.007 0.993 0.000
M07.38 Other psoriatic arthropathies (Other)
0.007 0.993 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.007 0.993 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.007 0.993 0.000
M14 Arthropathies in other diseases classified elsewhere
0.007 0.993 0.000
Y40.2 Chloramphenicol group
0.007 0.993 0.000
D61.8 Other specified aplastic anaemias
0.007 0.993 0.001
D61.3 Idiopathic aplastic anaemia
0.007 0.993 0.001
D61.2 Aplastic anaemia due to other external agents
0.007 0.993 0.001
T39.4 Antirheumatics, not elsewhere classified
0.007 0.993 0.000
T39.2 Pyrazolone derivatives
0.007 0.993 0.000
F20.0 Paranoid schizophrenia
0.007 0.993 0.000
T38.1 Thyroid hormones and substitutes
0.007 0.993 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.007 0.993 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.007 0.993 0.000
M05.8 Other seropositive rheumatoid arthritis
0.007 0.993 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.007 0.993 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.000 0.993 0.007
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.007 0.993 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.007 0.993 0.000
F60.9 Personality disorder, unspecified
0.007 0.993 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.007 0.993 0.000
D61.1 Drug-induced aplastic anaemia
0.006 0.993 0.001
M14.6 Neuropathic arthropathy
0.007 0.993 0.000
D51.2 Transcobalamin II deficiency
0.007 0.993 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.007 0.993 0.000
Y40.7 Antifungal antibiotics, systemically used
0.007 0.993 0.000
F38 Other mood [affective] disorders
0.007 0.993 0.000
I87.0 Postphlebitic syndrome
0.006 0.993 0.000
I87.9 Disorder of vein, unspecified
0.006 0.994 0.000
M07.6 Other enteropathic arthropathies
0.006 0.994 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.006 0.994 0.000
Y40.4 Tetracyclines
0.006 0.994 0.000
F60 Specific personality disorders
0.006 0.994 0.000
F34 Persistent mood [affective] disorders
0.006 0.994 0.000
M05.2 Rheumatoid vasculitis
0.006 0.994 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.006 0.994 0.000
M07.5 Arthropathy in ulcerative colitis
0.006 0.994 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.006 0.994 0.000
M07.2 Psoriatic spondylitis
0.006 0.994 0.000
M07.1 Arthritis mutilans
0.006 0.994 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.006 0.994 0.000
F60-F69 Disorders of adult personality and behaviour
0.006 0.994 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.006 0.994 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.006 0.994 0.000
M05.1 Rheumatoid lung disease
0.006 0.994 0.000
M05.0 Felty's syndrome
0.006 0.994 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.006 0.994 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.000 0.994 0.006
N02.9 Unspecified
0.000 0.994 0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.006 0.994 0.000
T39.0 Salicylates
0.006 0.994 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.006 0.994 0.000
D22.4 Melanocytic naevi of scalp and neck
0.000 0.994 0.006
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.006 0.994 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.006 0.994 0.000
M08 Juvenile arthritis
0.006 0.994 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.006 0.994 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.006 0.994 0.000
D61.0 Constitutional aplastic anaemia
0.005 0.994 0.001
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.006 0.994 0.000
F33 Recurrent depressive disorder
0.006 0.994 0.000
Y40.3 Macrolides
0.006 0.994 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.006 0.994 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.006 0.994 0.000
D52.8 Other folate deficiency anaemias
0.005 0.994 0.000
D52.1 Drug-induced folate deficiency anaemia
0.005 0.994 0.000
D52.0 Dietary folate deficiency anaemia
0.005 0.994 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.005 0.994 0.000
I82.2 Embolism and thrombosis of vena cava
0.005 0.994 0.000
F20 Schizophrenia
0.006 0.994 0.000
F23 Acute and transient psychotic disorders
0.006 0.994 0.000
F39 Unspecified mood [affective] disorder
0.005 0.994 0.000
M13 Other arthritis
0.006 0.994 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.005 0.994 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.006 0.994 0.000
Z86.7 Personal history of diseases of the circulatory system
0.006 0.994 0.000
E27.8 Other specified disorders of adrenal gland
0.006 0.994 0.000
I88.8 Other nonspecific lymphadenitis
0.005 0.994 0.000
M13.8 Other specified arthritis
0.005 0.994 0.000
F30 Manic episode
0.005 0.994 0.000
F64 Gender identity disorders
0.005 0.995 0.000
F69 Unspecified disorder of adult personality and behaviour
0.005 0.995 0.000
M12 Other specific arthropathies
0.005 0.995 0.000
M11 Other crystal arthropathies
0.005 0.995 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.005 0.995 0.000
M14.4 Arthropathy in amyloidosis
0.005 0.995 0.000
M14.3 Lipoid dermatoarthritis
0.005 0.995 0.000
M14.2 Diabetic arthropathy
0.005 0.995 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.005 0.995 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.005 0.995 0.000
Chapter V Mental and behavioural disorders
0.005 0.995 0.000
I87.8 Other specified disorders of veins
0.005 0.995 0.000
F25 Schizoaffective disorders
0.005 0.995 0.000
I85 Oesophageal varices
0.005 0.995 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.005 0.995 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.005 0.995 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.005 0.995 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.005 0.995 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.005 0.995 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.005 0.995 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.005 0.995 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.005 0.995 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.005 0.995 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.005 0.995 0.000
Z89.4 Acquired absence of foot and ankle
0.005 0.995 0.000
F60.0 Paranoid personality disorder
0.005 0.995 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.005 0.995 0.000
F60.6 Anxious [avoidant] personality disorder
0.005 0.995 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.005 0.995 0.000
M13.89 Other specified arthritis (Site unspecified)
0.005 0.995 0.000
F38.8 Other specified mood [affective] disorders
0.005 0.995 0.000
F38.1 Other recurrent mood [affective] disorders
0.005 0.995 0.000
F38.0 Other single mood [affective] disorders
0.005 0.995 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.005 0.995 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.005 0.995 0.000
F30.2 Mania with psychotic symptoms
0.005 0.995 0.000
F64.0 Transsexualism
0.005 0.995 0.000
F60.2 Dissocial personality disorder
0.005 0.995 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.005 0.995 0.000
M06 Other rheumatoid arthritis
0.005 0.995 0.000
M07.68 Other enteropathic arthropathies (Other)
0.005 0.995 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.005 0.995 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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