TreeWAS – Variant ID: rs11171739

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.004	0.996
J45.9 Asthma, unspecified	0.000	0.013	0.987
J33.9 Nasal polyp, unspecified	0.000	0.121	0.879
J33 Nasal polyp	0.000	0.132	0.868
J33.0 Polyp of nasal cavity	0.000	0.147	0.853
J33.8 Other polyp of sinus	0.000	0.181	0.819
J33.1 Polypoid sinus degeneration	0.000	0.315	0.684
E03 Other hypothyroidism	0.000	0.402	0.598
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.508	0.492
E03.8 Other specified hypothyroidism	0.000	0.509	0.491
J45 Asthma	0.000	0.510	0.490
E03.1 Congenital hypothyroidism without goitre	0.000	0.550	0.450
E10.3 With ophthalmic complications	0.000	0.556	0.444
E10 Insulin-dependent diabetes mellitus	0.000	0.557	0.443
E10.9 Without complications	0.000	0.563	0.437
E03.5 Myxoedema coma	0.000	0.571	0.429
E03.4 Atrophy of thyroid (acquired)	0.000	0.571	0.429
E03.3 Postinfectious hypothyroidism	0.000	0.571	0.429
J45.0 Predominantly allergic asthma	0.000	0.607	0.393
E10.5 With peripheral circulatory complications	0.000	0.612	0.388
E10.6 With other specified complications	0.000	0.626	0.374
E10.4 With neurological complications	0.000	0.630	0.370
E10.0 With coma	0.000	0.644	0.356
J45.8 Mixed asthma	0.000	0.645	0.355
J45.1 Nonallergic asthma	0.000	0.658	0.342
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.666	0.334
E10.2 With renal complications	0.000	0.670	0.330
E10.1 With ketoacidosis	0.000	0.677	0.323
E10.7 With multiple complications	0.000	0.695	0.305
E10.8 With unspecified complications	0.000	0.726	0.274
E10-E14 Diabetes mellitus	0.000	0.919	0.081
E00-E07 Disorders of thyroid gland	0.000	0.924	0.076
E13 Other specified diabetes mellitus	0.000	0.938	0.062
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.939	0.061
E12 Malnutrition-related diabetes mellitus	0.000	0.942	0.058
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.945	0.055
E00 Congenital iodine-deficiency syndrome	0.000	0.945	0.055
E06 Thyroiditis	0.000	0.947	0.053
E13.3 With ophthalmic complications	0.000	0.948	0.052
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.952	0.048
E13.8 With unspecified complications	0.000	0.955	0.045
E13.7 With multiple complications	0.000	0.955	0.045
E13.6 With other specified complications	0.000	0.955	0.045
E13.5 With peripheral circulatory complications	0.000	0.955	0.045
E13.4 With neurological complications	0.000	0.955	0.045
E13.2 With renal complications	0.000	0.955	0.045
E13.1 With ketoacidosis	0.000	0.955	0.045
E13.0 With coma	0.000	0.955	0.045
E06.3 Autoimmune thyroiditis	0.000	0.956	0.044
E12.9 Without complications	0.000	0.958	0.042
E12.8 With unspecified complications	0.000	0.958	0.042
E12.7 With multiple complications	0.000	0.958	0.042
E12.6 With other specified complications	0.000	0.958	0.042
E12.5 With peripheral circulatory complications	0.000	0.958	0.042
E12.4 With neurological complications	0.000	0.958	0.042
E12.3 With ophthalmic complications	0.000	0.958	0.042
E12.2 With renal complications	0.000	0.958	0.042
E12.1 With ketoacidosis	0.000	0.958	0.042
E12.0 With coma	0.000	0.958	0.042
E13.9 Without complications	0.000	0.960	0.040
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.960	0.039
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.960	0.039
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.960	0.039
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.960	0.039
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.960	0.039
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.960	0.039
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.960	0.039
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.960	0.039
E06.4 Drug-induced thyroiditis	0.000	0.962	0.038
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.962	0.038
E06.0 Acute thyroiditis	0.000	0.962	0.038
E06.5 Other chronic thyroiditis	0.000	0.963	0.037
E06.1 Subacute thyroiditis	0.000	0.964	0.036
E07 Other disorders of thyroid	0.000	0.967	0.033
E06.9 Thyroiditis, unspecified	0.000	0.969	0.031
E50-E64 Other nutritional deficiencies	0.000	0.970	0.030
E40-E46 Malnutrition	0.000	0.973	0.027
E65-E68 Obesity and other hyperalimentation	0.000	0.974	0.025
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.975	0.025
E56 Other vitamin deficiencies	0.000	0.976	0.024
E07.1 Dyshormogenetic goitre	0.000	0.976	0.024
E07.0 Hypersecretion of calcitonin	0.000	0.976	0.024
E54 Ascorbic acid deficiency	0.000	0.976	0.024
E07.8 Other specified disorders of thyroid	0.000	0.978	0.022
E51 Thiamine deficiency	0.000	0.978	0.022
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.978	0.022
E63 Other nutritional deficiencies	0.000	0.978	0.022
E50 Vitamin A deficiency	0.000	0.978	0.022
E60 Dietary zinc deficiency	0.000	0.978	0.022
E59 Dietary selenium deficiency	0.000	0.978	0.022
E52 Niacin deficiency [pellagra]	0.000	0.978	0.022
E58 Dietary calcium deficiency	0.000	0.979	0.021
E56.1 Deficiency of vitamin K	0.000	0.980	0.020
E65 Localised adiposity	0.000	0.980	0.020
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.980	0.020
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.980	0.020
E45 Retarded development following protein-energy malnutrition	0.000	0.980	0.020
E43 Unspecified severe protein-energy malnutrition	0.000	0.980	0.020
E42 Marasmic kwashiorkor	0.000	0.980	0.020
E41 Nutritional marasmus	0.000	0.980	0.020
E40 Kwashiorkor	0.000	0.980	0.020
E55 Vitamin D deficiency	0.000	0.980	0.019
E53 Deficiency of other B group vitamins	0.000	0.981	0.019
E67 Other hyperalimentation	0.000	0.981	0.018
E68 Sequelae of hyperalimentation	0.000	0.981	0.018
E15 Nondiabetic hypoglycaemic coma	0.000	0.982	0.018
E56.9 Vitamin deficiency, unspecified	0.000	0.982	0.018
E56.8 Deficiency of other vitamins	0.000	0.982	0.018
E56.0 Deficiency of vitamin E	0.000	0.982	0.018
E51.2 Wernicke's encephalopathy	0.000	0.984	0.016
E51.9 Thiamine deficiency, unspecified	0.000	0.984	0.016
E51.8 Other manifestations of thiamine deficiency	0.000	0.984	0.016
E51.1 Beriberi	0.000	0.984	0.016
E14 Unspecified diabetes mellitus	0.000	0.984	0.016
E50.9 Vitamin A deficiency, unspecified	0.000	0.984	0.016
E50.8 Other manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.984	0.016
E50.5 Vitamin A deficiency with night blindness	0.000	0.984	0.016
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.984	0.016
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.984	0.016
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.984	0.016
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.984	0.016
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.984	0.016
E63.9 Nutritional deficiency, unspecified	0.000	0.984	0.016
E63.8 Other specified nutritional deficiencies	0.000	0.984	0.016
E63.1 Imbalance of constituents of food intake	0.000	0.984	0.016
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.984	0.016
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.984	0.016
E64.8 Sequelae of other nutritional deficiencies	0.000	0.984	0.016
E64.3 Sequelae of rickets	0.000	0.984	0.016
E64.2 Sequelae of vitamin C deficiency	0.000	0.984	0.016
E64.1 Sequelae of vitamin A deficiency	0.000	0.984	0.016
E64.0 Sequelae of protein-energy malnutrition	0.000	0.984	0.016
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.985	0.015
J35.0 Chronic tonsillitis	0.015	0.985	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.985	0.015
E05.5 Thyroid crisis or storm	0.000	0.985	0.015
E05.4 Thyrotoxicosis factitia	0.000	0.985	0.015
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.985	0.015
E44.1 Mild protein-energy malnutrition	0.000	0.985	0.014
E44.0 Moderate protein-energy malnutrition	0.000	0.985	0.014
E05.8 Other thyrotoxicosis	0.000	0.986	0.014
E55.0 Rickets, active	0.000	0.986	0.014
E53.1 Pyridoxine deficiency	0.000	0.986	0.014
E53.0 Riboflavin deficiency	0.000	0.986	0.014
E53.9 Vitamin B deficiency, unspecified	0.000	0.986	0.014
C09.9 Tonsil, unspecified	0.014	0.986	0.000
E67.8 Other specified hyperalimentation	0.000	0.986	0.013
E67.3 Hypervitaminosis D	0.000	0.986	0.013
E67.2 Megavitamin-B6 syndrome	0.000	0.986	0.013
E67.1 Hypercarotenaemia	0.000	0.986	0.013
E67.0 Hypervitaminosis A	0.000	0.986	0.013
E61 Deficiency of other nutrient elements	0.000	0.987	0.013
K74.5 Biliary cirrhosis, unspecified	0.013	0.987	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.988	0.012
E53.8 Deficiency of other specified B group vitamins	0.000	0.988	0.012
E55.9 Vitamin D deficiency, unspecified	0.000	0.988	0.012
E14.6 With other specified complications	0.000	0.988	0.012
E14.7 With multiple complications	0.000	0.988	0.011
E14.5 With peripheral circulatory complications	0.000	0.989	0.011
E14.0 With coma	0.000	0.989	0.011
E14.4 With neurological complications	0.000	0.989	0.011
E14.1 With ketoacidosis	0.000	0.989	0.010
E14.2 Withrenal complications	0.000	0.990	0.010
E14.8 With unspecified complications	0.000	0.990	0.010
E61.9 Deficiency of nutrient element, unspecified	0.000	0.990	0.009
E61.8 Deficiency of other specified nutrient elements	0.000	0.990	0.009
E61.7 Deficiency of multiple nutrient elements	0.000	0.990	0.009
E61.6 Vanadium deficiency	0.000	0.990	0.009
E61.5 Molybdenum deficiency	0.000	0.990	0.009
E61.4 Chromium deficiency	0.000	0.990	0.009
E61.3 Manganese deficiency	0.000	0.990	0.009
E61.0 Copper deficiency	0.000	0.990	0.009
K74 Fibrosis and cirrhosis of liver	0.010	0.990	0.000
K74.3 Primary biliary cirrhosis	0.009	0.991	0.000
M95.0 Acquired deformity of nose	0.008	0.992	0.000
R40.2 Coma, unspecified	0.000	0.992	0.008
K74.0 Hepatic fibrosis	0.008	0.992	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.992	0.008
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.992	0.008
E07.9 Disorder of thyroid, unspecified	0.000	0.992	0.007
K74.1 Hepatic sclerosis	0.008	0.992	0.000
E61.2 Magnesium deficiency	0.000	0.993	0.007
K74.6 Other and unspecified cirrhosis of liver	0.007	0.993	0.000
K74.4 Secondary biliary cirrhosis	0.007	0.993	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.007	0.993	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.993	0.007
C09 Malignant neoplasm of tonsil	0.007	0.993	0.000
E14.3 With ophthalmic complications	0.000	0.993	0.007
C80.9 Malignant neoplasm, unspecified	0.007	0.993	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.994	0.006
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.006	0.994	0.000
E14.9 Without complications	0.000	0.994	0.006
E04 Other non-toxic goitre	0.000	0.994	0.006
H43.1 Vitreous haemorrhage	0.000	0.994	0.006
M95.4 Acquired deformity of chest and rib	0.006	0.994	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.994	0.006
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.994	0.006
E16.4 Abnormal secretion of gastrin	0.000	0.994	0.006
E16.3 Increased secretion of glucagon	0.000	0.994	0.006
J35 Chronic diseases of tonsils and adenoids	0.006	0.994	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.006	0.994	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.006	0.994	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.994	0.006
E61.1 Iron deficiency	0.000	0.994	0.006
S52.0 Fracture of upper end of ulna	0.000	0.994	0.006
C09.1 Tonsillar pillar (anterior) (posterior)	0.005	0.994	0.000
S52.01 Fracture of upper end of ulna (open)	0.000	0.994	0.005
C09.8 Overlapping lesion of tonsil	0.005	0.995	0.000
C09.0 Tonsillar fossa	0.005	0.995	0.000
E16.1 Other hypoglycaemia	0.000	0.995	0.005
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.005	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.995	0.005
F40.2 Specific (isolated) phobias	0.005	0.995	0.000
J35.2 Hypertrophy of adenoids	0.005	0.995	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.005	0.995	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.005	0.995	0.000
M95.5 Acquired deformity of pelvis	0.005	0.995	0.000
E04.8 Other specified non-toxic goitre	0.000	0.995	0.005
M95.3 Acquired deformity of neck	0.005	0.995	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.995	0.005
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.004	0.995	0.000
M95.2 Other acquired deformity of head	0.004	0.996	0.000
M07.3 Other psoriatic arthropathies	0.000	0.996	0.004
E66 Obesity	0.001	0.996	0.003
M95.1 Cauliflower ear	0.004	0.996	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.996	0.004
L40.0 Psoriasis vulgaris	0.000	0.996	0.004
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996	0.000
J35.1 Hypertrophy of tonsils	0.004	0.996	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.004	0.996	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.996	0.004
M46.9 Inflammatory spondylopathy, unspecified	0.004	0.996	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.996	0.004
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.004	0.996	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.004	0.996	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.996	0.004
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.004	0.996	0.000
L40.8 Other psoriasis	0.000	0.996	0.004
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.004	0.996	0.000
K37 Unspecified appendicitis	0.000	0.996	0.004
C45.0 Mesothelioma of pleura	0.000	0.996	0.004
K43.0 Ventral hernia with obstruction, without gangrene	0.004	0.996	0.000
L40 Psoriasis	0.000	0.996	0.004
S79.9 Unspecified injury of hip and thigh	0.004	0.996	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.997	0.003
L40.9 Psoriasis, unspecified	0.000	0.997	0.003
Q18.1 Preauricular sinus and cyst	0.000	0.997	0.003
M96.5 Postradiation scoliosis	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
R40.0 Somnolence	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
M07.38 Other psoriatic arthropathies (Other)	0.000	0.997	0.003
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.997	0.003
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.997	0.003
E66.1 Drug-induced obesity	0.001	0.997	0.002
J41 Simple and mucopurulent chronic bronchitis	0.000	0.997	0.003
J43 Emphysema	0.000	0.997	0.003
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
C45 Mesothelioma	0.000	0.997	0.003
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.003	0.997	0.000
M96.4 Postsurgical lordosis	0.003	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.003	0.997	0.000
M96.2 Postradiation kyphosis	0.003	0.997	0.000
S52.8 Fracture of other parts of forearm	0.000	0.997	0.003
H92.1 Otorrhoea	0.003	0.997	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.997	0.003
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
C79.9 Secondary malignant neoplasm, unspecified site	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.001	0.997	0.002
L40.5 Arthropathic psoriasis	0.000	0.997	0.003
C45.9 Mesothelioma, unspecified	0.000	0.997	0.003
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.003	0.997	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.003	0.997	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.997	0.003
E66.0 Obesity due to excess calories	0.001	0.997	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.997	0.003
T17.5 Foreign body in bronchus	0.003	0.997	0.000
C80 Malignant neoplasm without specification of site	0.003	0.997	0.000
E20 Hypoparathyroidism	0.000	0.997	0.003
S52 Fracture of forearm	0.000	0.997	0.003
L40.4 Guttate psoriasis	0.000	0.997	0.003
L40.2 Acrodermatitis continua	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.003
E11 Non-insulin-dependent diabetes mellitus	0.000	0.997	0.003
E24 Cushing's syndrome	0.000	0.997	0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
R44.1 Visual hallucinations	0.000	0.997	0.003
E26 Hyperaldosteronism	0.000	0.997	0.003
J43.8 Other emphysema	0.000	0.997	0.003
M99 Biomechanical lesions, not elsewhere classified	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
E66.9 Obesity, unspecified	0.003	0.997	0.000
E28 Ovarian dysfunction	0.000	0.997	0.003
N34.2 Other urethritis	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
J41.0 Simple chronic bronchitis	0.000	0.997	0.002
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.997	0.002
J41.1 Mucopurulent chronic bronchitis	0.000	0.997	0.002
J43.1 Panlobular emphysema	0.000	0.997	0.002
J43.0 MacLeod's syndrome	0.000	0.997	0.002
S52.81 Fracture of other parts of forearm (open)	0.000	0.997	0.002
C45.2 Mesothelioma of pericardium	0.000	0.997	0.002
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.002
N61 Inflammatory disorders of breast	0.003	0.997	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.997	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.997	0.000
E32 Diseases of thymus	0.000	0.997	0.002
R40 Somnolence, stupor and coma	0.000	0.997	0.002
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.000	0.997	0.002
L40.3 Pustulosis palmaris et plantaris	0.000	0.997	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.997	0.002
J43.2 Centrilobular emphysema	0.000	0.997	0.002
Q18 Other congenital malformations of face and neck	0.000	0.997	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.002	0.997	0.000
Q17.5 Prominent ear	0.000	0.997	0.002
J43.9 Emphysema, unspecified	0.000	0.998	0.002
L40.1 Generalised pustular psoriasis	0.000	0.998	0.002
S52.2 Fracture of shaft of ulna	0.000	0.998	0.002
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
R78.0 Finding of alcohol in blood	0.002	0.998	0.000
E34 Other endocrine disorders	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
M17.0 Primary gonarthrosis, bilateral	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.998	0.002
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
A04.8 Other specified bacterial intestinal infections	0.002	0.998	0.000
G90.2 Horner's syndrome	0.002	0.998	0.000
S52.9 Fracture of forearm, part unspecified	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
R40.1 Stupor	0.000	0.998	0.002
S52.7 Multiple fractures of forearm	0.000	0.998	0.002
E11.7 With multiple complications	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
M99.9 Biomechanical lesion, unspecified	0.002	0.998	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.4 Connective tissue stenosis of neural canal	0.002	0.998	0.000
M99.3 Osseous stenosis of neural canal	0.002	0.998	0.000
M99.2 Subluxation stenosis of neural canal	0.002	0.998	0.000
M99.1 Subluxation complex (vertebral)	0.002	0.998	0.000
M99.0 Segmental and somatic dysfunction	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.000	0.998	0.002
S52.3 Fracture of shaft of radius	0.000	0.998	0.002
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
M99.8 Other biomechanical lesions	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.000	0.998	0.002
E29 Testicular dysfunction	0.001	0.998	0.002
T17 Foreign body in respiratory tract	0.002	0.998	0.000
E11.2 With renal complications	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E11.6 With other specified complications	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
G90.3 Multisystem degeneration	0.002	0.998	0.000
E11.8 With unspecified complications	0.000	0.998	0.002
E11.0 With coma	0.000	0.998	0.002
M99.5 Intervertebral disk stenosis of neural canal	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.000	0.998	0.002
Q18.8 Other specified congenital malformations of face and neck	0.000	0.998	0.002
Q18.7 Microcheilia	0.000	0.998	0.002
Q18.6 Macrocheilia	0.000	0.998	0.002
Q18.5 Microstomia	0.000	0.998	0.002
Q18.4 Macrostomia	0.000	0.998	0.002
Q18.3 Webbing of neck	0.000	0.998	0.002
Q18.2 Other branchial cleft malformations	0.000	0.998	0.002
M75.5 Bursitis of shoulder	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
S52.71 Multiple fractures of forearm (open)	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.998	0.002
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
Q10.0 Congenital ptosis	0.000	0.998	0.002
T17.8 Foreign body in other and multiple parts of respiratory tract	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.000	0.998	0.002
G90.4 Autonomic dysreflexia	0.002	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.002	0.998	0.000
S79 Other and unspecified injuries of hip and thigh	0.002	0.998	0.000
S52.5 Fracture of lower end of radius	0.000	0.998	0.002
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.998	0.002
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
J47 Bronchiectasis	0.000	0.998	0.002
M99.09 Segmental and somatic dysfunction (Abdomen and other)	0.002	0.998	0.000
M99.08 Segmental and somatic dysfunction (Rib cage)	0.002	0.998	0.000
M99.07 Segmental and somatic dysfunction (Upper extremity)	0.002	0.998	0.000
M99.06 Segmental and somatic dysfunction (Lower extremity)	0.002	0.998	0.000
M99.05 Segmental and somatic dysfunction (Pelvic region)	0.002	0.998	0.000
M99.04 Segmental and somatic dysfunction (Sacral region)	0.002	0.998	0.000
M99.03 Segmental and somatic dysfunction (Lumbar region)	0.002	0.998	0.000
M99.02 Segmental and somatic dysfunction (Thoracic region)	0.002	0.998	0.000
M99.01 Segmental and somatic dysfunction (Cervical region)	0.002	0.998	0.000
M99.00 Segmental and somatic dysfunction (Head region)	0.002	0.998	0.000
M99.19 Subluxation complex (vertebral) (Abdomen and other)	0.002	0.998	0.000
M99.18 Subluxation complex (vertebral) (Rib cage)	0.002	0.998	0.000
M99.17 Subluxation complex (vertebral) (Upper extremity)	0.002	0.998	0.000
M99.16 Subluxation complex (vertebral) (Lower extremity)	0.002	0.998	0.000
M99.15 Subluxation complex (vertebral) (Pelvic region)	0.002	0.998	0.000
M99.14 Subluxation complex (vertebral) (Sacral region)	0.002	0.998	0.000
M99.13 Subluxation complex (vertebral) (Lumbar region)	0.002	0.998	0.000
M99.12 Subluxation complex (vertebral) (Thoracic region)	0.002	0.998	0.000
M99.11 Subluxation complex (vertebral) (Cervical region)	0.002	0.998	0.000
M99.10 Subluxation complex (vertebral) (Head region)	0.002	0.998	0.000
M99.29 Subluxation stenosis of neural canal-Abdomen/other	0.002	0.998	0.000
M99.28 Subluxation stenosis of neural canal-Rib cage	0.002	0.998	0.000
M99.27 Subluxation stenosis of neural canal-Upper extremity	0.002	0.998	0.000
M99.26 Subluxation stenosis of neural canal-Lower extremity	0.002	0.998	0.000
M99.25 Subluxation stenosis of neural canal (Pelvic region)	0.002	0.998	0.000
M99.24 Subluxation stenosis of neural canal (Sacral region)	0.002	0.998	0.000
M99.23 Subluxation stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
M99.22 Subluxation stenosis of neural canal (Thoracic region)	0.002	0.998	0.000
M99.21 Subluxation stenosis of neural canal (Cervical region)	0.002	0.998	0.000
M99.20 Subluxation stenosis of neural canal (Head region)	0.002	0.998	0.000
M99.39 Osseous stenosis of neural canal-Abdomen/other	0.002	0.998	0.000
M99.38 Osseous stenosis of neural canal-Rib cage	0.002	0.998	0.000
M99.37 Osseous stenosis of neural canal-Upper extremity	0.002	0.998	0.000
M99.36 Osseous stenosis of neural canal-Lower extremity	0.002	0.998	0.000
M99.35 Osseous stenosis of neural canal (Pelvic region)	0.002	0.998	0.000
M99.34 Osseous stenosis of neural canal (Sacral region)	0.002	0.998	0.000
M99.33 Osseous stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
M99.32 Osseous stenosis of neural canal (Thoracic region)	0.002	0.998	0.000
M99.31 Osseous stenosis of neural canal (Cervical region)	0.002	0.998	0.000
M99.30 Osseous stenosis of neural canal (Head region)	0.002	0.998	0.000
M99.49 Connective tissue stenosis of neural canal-Abdomen/other	0.002	0.998	0.000
M99.48 Connective tissue stenosis of neural canal-Rib cage	0.002	0.998	0.000
M99.47 Connective tissue stenosis of neural canal-Upper extremity	0.002	0.998	0.000
M99.46 Connective tissue stenosis of neural canal-Lower extremity	0.002	0.998	0.000
M99.45 Connective tissue stenosis of neural canal (Pelvic region)	0.002	0.998	0.000
M99.44 Connective tissue stenosis of neural canal (Sacral region)	0.002	0.998	0.000
M99.43 Connective tissue stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
M99.42 Connective tissue stenosis of neural canal (Thoracic region)	0.002	0.998	0.000
M99.41 Connective tissue stenosis of neural canal (Cervical region)	0.002	0.998	0.000
M99.40 Connective tissue stenosis of neural canal (Head region)	0.002	0.998	0.000
M99.69 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.68 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.67 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.66 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.65 Osseous and subluxation stenosis of intervertebral foramina (Pelvic region)	0.002	0.998	0.000
M99.64 Osseous and subluxation stenosis of intervertebral foramina (Sacral region)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations