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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111797345
log Bayes Factor = 22.7323
Chromosome 3   position 69,168,628  (GRCh37) Explore rs111797345 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
J09-J18 Influenza and pneumonia
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.995 0.005 0.000
J18 Pneumonia, organism unspecified
0.994 0.006 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.993 0.007 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
H65-H75 Diseases of middle ear and mastoid
0.988 0.012 0.000
Y95 Nosocomial condition
0.988 0.012 0.000
J18.9 Pneumonia, unspecified
0.987 0.013 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.984 0.016 0.000
J30-J39 Other diseases of upper respiratory tract
0.980 0.020 0.000
T81 Complications of procedures, not elsewhere classified
0.979 0.021 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.978 0.022 0.000
S60-S69 Injuries to the wrist and hand
0.976 0.024 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.974 0.026 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.972 0.028 0.000
R47-R49 Symptoms and signs involving speech and voice
0.962 0.038 0.000
M23 Internal derangement of knee
0.961 0.039 0.000
Chapter II Neoplasms
0.958 0.042 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.951 0.049 0.000
J32 Chronic sinusitis
0.944 0.056 0.000
S20-S29 Injuries to the thorax
0.944 0.056 0.000
H25-H28 Disorders of lens
0.941 0.059 0.000
H30-H36 Disorders of choroid and retina
0.938 0.062 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.938 0.062 0.000
H60-H62 Diseases of external ear
0.936 0.064 0.000
H66 Suppurative and unspecified otitis media
0.932 0.068 0.000
I60-I69 Cerebrovascular diseases
0.930 0.070 0.000
R47 Speech disturbances, not elsewhere classified
0.930 0.070 0.000
S90-S99 Injuries to the ankle and foot
0.928 0.072 0.000
J18.1 Lobar pneumonia, unspecified
0.927 0.073 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.927 0.073 0.000
C15-C26 Malignant neoplasms of digestive organs
0.924 0.076 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.918 0.082 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.917 0.083 0.000
H25 Senile cataract
0.916 0.084 0.000
Chapter VI Diseases of the nervous system
0.912 0.088 0.000
S61 Open wound of wrist and hand
0.911 0.089 0.000
J90-J94 Other diseases of pleura
0.910 0.090 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.909 0.091 0.000
M25 Other joint disorders, not elsewhere classified
0.908 0.092 0.000
T66-T78 Other and unspecified effects of external causes
0.908 0.092 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.905 0.095 0.000
J32.9 Chronic sinusitis, unspecified
0.903 0.097 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.903 0.097 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.901 0.099 0.000
R94 Abnormal results of function studies
0.898 0.102 0.000
H35 Other retinal disorders
0.897 0.103 0.000
H25.1 Senile nuclear cataract
0.895 0.105 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.893 0.107 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.892 0.108 0.000
C34 Malignant neoplasm of bronchus and lung
0.892 0.108 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.888 0.112 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.883 0.117 0.000
I81 Portal vein thrombosis
0.880 0.120 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.879 0.121 0.000
H35.3 Degeneration of macula and posterior pole
0.879 0.121 0.000
R47.0 Dysphasia and aphasia
0.878 0.122 0.000
I84 Haemorrhoids
0.877 0.123 0.000
H61 Other disorders of external ear
0.876 0.124 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.875 0.125 0.000
C34.9 Bronchus or lung, unspecified
0.874 0.126 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.872 0.128 0.000
H80-H83 Diseases of inner ear
0.871 0.128 0.000
A30-A49 Other bacterial diseases
0.870 0.130 0.000
I86 Varicose veins of other sites
0.868 0.132 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.866 0.134 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.866 0.134 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.864 0.136 0.000
J20-J22 Other acute lower respiratory infections
0.863 0.137 0.000
I80 Phlebitis and thrombophlebitis
0.863 0.137 0.000
I85 Oesophageal varices
0.861 0.139 0.000
W00-W19 Falls
0.861 0.139 0.000
M65-M68 Disorders of synovium and tendon
0.859 0.141 0.000
H53-H54 Visual disturbances and blindness
0.856 0.144 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.856 0.144 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.852 0.148 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.852 0.148 0.000
I69 Sequelae of cerebrovascular disease
0.851 0.149 0.000
S61.8 Open wound of other parts of wrist and hand
0.850 0.150 0.000
I31 Other diseases of pericardium
0.850 0.150 0.000
I42 Cardiomyopathy
0.850 0.150 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.850 0.150 0.000
I51 Complications and ill-defined descriptions of heart disease
0.848 0.152 0.000
R42 Dizziness and giddiness
0.848 0.152 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.848 0.152 0.000
R25 Abnormal involuntary movements
0.846 0.154 0.000
S22.4 Multiple fractures of ribs
0.842 0.158 0.000
T78 Adverse effects, not elsewhere classified
0.841 0.159 0.000
R29.6 Tendency to fall, not elsewhere classified
0.839 0.161 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.836 0.164 0.000
R50-R69 General symptoms and signs
0.835 0.165 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.831 0.169 0.000
M21 Other acquired deformities of limbs
0.830 0.170 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.829 0.171 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.828 0.172 0.000
S40-S49 Injuries to the shoulder and upper arm
0.828 0.172 0.000
R45 Symptoms and signs involving emotional state
0.827 0.173 0.000
M31 Other necrotising vasculopathies
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.822 0.178 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.822 0.178 0.000
H74 Other disorders of middle ear and mastoid
0.818 0.182 0.000
H70 Mastoiditis and related conditions
0.818 0.182 0.000
I33 Acute and subacute endocarditis
0.817 0.183 0.000
J32.2 Chronic ethmoidal sinusitis
0.817 0.183 0.000
S92 Fracture of foot, except ankle
0.817 0.183 0.000
C15 Malignant neoplasm of oesophagus
0.816 0.184 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.813 0.187 0.000
M24 Other specific joint derangements
0.812 0.188 0.000
I47 Paroxysmal tachycardia
0.812 0.188 0.000
J90 Pleural effusion, not elsewhere classified
0.810 0.190 0.000
T81.9 Unspecified complication of procedure
0.810 0.190 0.000
J35 Chronic diseases of tonsils and adenoids
0.810 0.190 0.000
R94.3 Abnormal results of cardiovascular function studies
0.810 0.190 0.000
H65 Nonsuppurative otitis media
0.808 0.192 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.808 0.192 0.000
M80-M85 Disorders of bone density and structure
0.807 0.193 0.000
H66.9 Otitis media, unspecified
0.807 0.193 0.000
S22.40 Multiple fractures of ribs (closed)
0.806 0.194 0.000
H61.2 Impacted cerumen
0.805 0.195 0.000
I84.8 Unspecified haemorrhoids with other complications
0.805 0.195 0.000
S00-S09 Injuries to the head
0.804 0.196 0.000
I84.9 Unspecified haemorrhoids without complication
0.804 0.196 0.000
M25.4 Effusion of joint
0.803 0.197 0.000
M91-M94 Chondropathies
0.800 0.200 0.000
I38 Endocarditis, valve unspecified
0.800 0.200 0.000
V10-V19 Pedal cyclist injured in transport accident
0.800 0.200 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.799 0.201 0.000
J10 Influenza due to identified influenza virus
0.799 0.201 0.000
G90-G99 Other disorders of the nervous system
0.798 0.202 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.796 0.204 0.000
R51 Headache
0.794 0.206 0.000
C16 Malignant neoplasm of stomach
0.793 0.207 0.000
C85.1 B-cell lymphoma, unspecified
0.793 0.207 0.000
M22 Disorders of patella
0.792 0.208 0.000
M86-M90 Other osteopathies
0.791 0.209 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.791 0.209 0.000
R27 Other lack of coordination
0.789 0.211 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.788 0.211 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.787 0.213 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.786 0.213 0.000
S80-S89 Injuries to the knee and lower leg
0.785 0.214 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.785 0.215 0.000
R26 Abnormalities of gait and mobility
0.784 0.215 0.000
H66.3 Other chronic suppurative otitis media
0.784 0.216 0.000
H69 Other disorders of Eustachian tube
0.783 0.216 0.000
H55-H59 Other disorders of eye and adnexa
0.783 0.217 0.000
M23.4 Loose body in knee
0.782 0.218 0.000
H66.4 Suppurative otitis media, unspecified
0.782 0.218 0.000
C91 Lymphoid leukaemia
0.781 0.219 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.781 0.219 0.000
J33 Nasal polyp
0.780 0.220 0.000
S64 Injury of nerves at wrist and hand level
0.780 0.220 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.779 0.221 0.000
H53 Visual disturbances
0.779 0.221 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.777 0.223 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.777 0.223 0.000
I36 Nonrheumatic tricuspid valve disorders
0.774 0.226 0.000
I49 Other cardiac arrhythmias
0.774 0.226 0.000
A80-A89 Viral infections of the central nervous system
0.773 0.227 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.773 0.227 0.000
T82.3 Mechanical complication of other vascular grafts
0.773 0.227 0.000
I61 Intracerebral haemorrhage
0.772 0.228 0.000
R47.8 Other and unspecified speech disturbances
0.772 0.228 0.000
J00-J06 Acute upper respiratory infections
0.771 0.229 0.000
B35-B49 Mycoses
0.770 0.230 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.769 0.231 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.768 0.232 0.000
J38.0 Paralysis of vocal cords and larynx
0.767 0.233 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.767 0.233 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.767 0.233 0.000
I85.9 Oesophageal varices without bleeding
0.766 0.234 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.765 0.235 0.000
J22 Unspecified acute lower respiratory infection
0.765 0.235 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.764 0.236 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.763 0.237 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.763 0.237 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.762 0.238 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.762 0.238 0.000
I82 Other venous embolism and thrombosis
0.761 0.239 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.761 0.239 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.760 0.240 0.000
M23.3 Other meniscus derangements
0.759 0.241 0.000
C32 Malignant neoplasm of larynx
0.758 0.242 0.000
I60 Subarachnoid haemorrhage
0.757 0.243 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.757 0.243 0.000
S61.0 Open wound of finger(s) without damage to nail
0.757 0.243 0.000
S68 Traumatic amputation of wrist and hand
0.757 0.243 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.757 0.243 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.754 0.246 0.000
A41 Other septicaemia
0.754 0.246 0.000
J38.3 Other diseases of vocal cords
0.753 0.247 0.000
J60-J70 Lung diseases due to external agents
0.753 0.247 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.753 0.247 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.752 0.248 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
I51.8 Other ill-defined heart diseases
0.750 0.250 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.749 0.251 0.000
M70-M79 Other soft tissue disorders
0.749 0.251 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.748 0.252 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.747 0.252 0.000
I37 Pulmonary valve disorders
0.747 0.253 0.000
H10-H13 Disorders of conjunctiva
0.747 0.253 0.000
H71 Cholesteatoma of middle ear
0.747 0.253 0.000
S27 Injury of other and unspecified intrathoracic organs
0.746 0.254 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.746 0.254 0.000
H72 Perforation of tympanic membrane
0.746 0.254 0.000
T78.4 Allergy, unspecified
0.746 0.254 0.000
M25.5 Pain in joint
0.745 0.255 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.745 0.255 0.000
C18 Malignant neoplasm of colon
0.745 0.255 0.000
H90-H95 Other disorders of ear
0.744 0.256 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.744 0.256 0.000
H25.8 Other senile cataract
0.743 0.257 0.000
J95-J99 Other diseases of the respiratory system
0.742 0.258 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.742 0.258 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.742 0.258 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.741 0.259 0.000
I86.4 Gastric varices
0.739 0.261 0.000
H60 Otitis externa
0.738 0.261 0.000
A00-A09 Intestinal infectious diseases
0.738 0.262 0.000
I31.9 Disease of pericardium, unspecified
0.738 0.262 0.000
R49 Voice disturbances
0.736 0.264 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.736 0.264 0.000
I87 Other disorders of veins
0.735 0.265 0.000
H83 Other diseases of inner ear
0.735 0.265 0.000
R47.1 Dysarthria and anarthria
0.734 0.266 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.734 0.266 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.733 0.266 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.733 0.267 0.000
R40 Somnolence, stupor and coma
0.733 0.267 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.731 0.269 0.000
R25.2 Cramp and spasm
0.730 0.270 0.000
H81 Disorders of vestibular function
0.730 0.270 0.000
M65 Synovitis and tenosynovitis
0.730 0.270 0.000
M25.46 Effusion of joint (Lower leg)
0.727 0.273 0.000
H61.0 Perichondritis of external ear
0.725 0.275 0.000
J39 Other diseases of upper respiratory tract
0.724 0.276 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.724 0.276 0.000
M23.5 Chronic instability of knee
0.724 0.276 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.723 0.277 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.723 0.277 0.000
H43-H45 Disorders of vitreous body and globe
0.723 0.277 0.000
H34 Retinal vascular occlusions
0.723 0.277 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.723 0.277 0.000
J11 Influenza, virus not identified
0.721 0.279 0.000
R59 Enlarged lymph nodes
0.721 0.279 0.000
S99 Other and unspecified injuries of ankle and foot
0.720 0.280 0.000
J93 Pneumothorax
0.720 0.280 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.717 0.282 0.000
I69.3 Sequelae of cerebral infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.716 0.284 0.000
S42 Fracture of shoulder and upper arm
0.716 0.284 0.000
H25.9 Senile cataract, unspecified
0.715 0.285 0.000
J17 Pneumonia in diseases classified elsewhere
0.715 0.285 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.715 0.285 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.715 0.285 0.000
J12 Viral pneumonia, not elsewhere classified
0.715 0.285 0.000
J14 Pneumonia due to Haemophilus influenzae
0.715 0.285 0.000
J09 Influenza due to certain identified influenza virus
0.715 0.285 0.000
I89.0 Lymphoedema, not elsewhere classified
0.715 0.285 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.715 0.285 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.713 0.287 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.713 0.287 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
J18.8 Other pneumonia, organism unspecified
0.713 0.287 0.000
J18.2 Hypostatic pneumonia, unspecified
0.713 0.287 0.000
R94.5 Abnormal results of liver function studies
0.713 0.287 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.713 0.287 0.000
J38.2 Nodules of vocal cords
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.712 0.288 0.000
I88 Nonspecific lymphadenitis
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
I47.2 Ventricular tachycardia
0.712 0.288 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.712 0.288 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.712 0.288 0.000
Y98 Lifestyle-related condition
0.712 0.288 0.000
Y97 Environmental-pollution-related condition
0.712 0.288 0.000
Y96 Work-related condition
0.712 0.288 0.000
S22.5 Flail chest
0.711 0.289 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
J35.1 Hypertrophy of tonsils
0.711 0.289 0.000
J38.7 Other diseases of larynx
0.710 0.290 0.000
H73 Other disorders of tympanic membrane
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M34 Systemic sclerosis
0.710 0.290 0.000
M33 Dermatopolymyositis
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.709 0.291 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.709 0.291 0.000
H68 Eustachian salpingitis and obstruction
0.709 0.291 0.000
H67 Otitis media in diseases classified elsewhere
0.709 0.291 0.000
S29 Other and unspecified injuries of thorax
0.708 0.292 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.708 0.292 0.000
I63 Cerebral infarction
0.706 0.294 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.705 0.295 0.000
I33.0 Acute and subacute infective endocarditis
0.705 0.295 0.000
W06 Fall involving bed
0.705 0.295 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.704 0.295 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.297 0.000
Y40 Systemic antibiotics
0.703 0.297 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.702 0.298 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.702 0.298 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.702 0.298 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.702 0.298 0.000
Chapter V Mental and behavioural disorders
0.702 0.298 0.000
J03 Acute tonsillitis
0.702 0.298 0.000
S92.3 Fracture of metatarsal bone
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
S67 Crushing injury of wrist and hand
0.700 0.300 0.000
S69 Other and unspecified injuries of wrist and hand
0.700 0.300 0.000
S65 Injury of blood vessels at wrist and hand level
0.700 0.300 0.000
M84 Disorders of continuity of bone
0.700 0.300 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.699 0.301 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.699 0.301 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.699 0.301 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.699 0.301 0.000
H33 Retinal detachments and breaks
0.699 0.301 0.000
S91 Open wound of ankle and foot
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.698 0.302 0.000
I48 Atrial fibrillation and flutter
0.698 0.302 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.698 0.302 0.000
I41 Myocarditis in diseases classified elsewhere
0.698 0.302 0.000
I40 Acute myocarditis
0.698 0.302 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.698 0.302 0.000
I32 Pericarditis in diseases classified elsewhere
0.698 0.302 0.000
I30 Acute pericarditis
0.698 0.302 0.000
C15.5 Lower third of oesophagus
0.698 0.302 0.000
I62 Other nontraumatic intracranial haemorrhage
0.698 0.302 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.698 0.302 0.000
J92 Pleural plaque
0.697 0.302 0.000
T18 Foreign body in alimentary tract
0.697 0.303 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.697 0.303 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.697 0.303 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.697 0.303 0.000
I84.3 External thrombosed haemorrhoids
0.696 0.303 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.696 0.304 0.000
I86.1 Scrotal varices
0.696 0.304 0.000
H70.9 Mastoiditis, unspecified
0.695 0.305 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.695 0.305 0.000
C21 Malignant neoplasm of anus and anal canal
0.695 0.305 0.000
S00 Superficial injury of head
0.694 0.306 0.000
Y52 Agents primarily affecting the cardiovascular system
0.694 0.306 0.000
R45.8 Other symptoms and signs involving emotional state
0.694 0.306 0.000
R57 Shock, not elsewhere classified
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.307 0.000
I42.0 Dilated cardiomyopathy
0.691 0.309 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.691 0.309 0.000
R56 Convulsions, not elsewhere classified
0.690 0.310 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.690 0.310 0.000
R94.4 Abnormal results of kidney function studies
0.690 0.310 0.000
G30-G32 Other degenerative diseases of the nervous system
0.690 0.310 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.689 0.311 0.000
M23.9 Internal derangement of knee, unspecified
0.689 0.311 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.689 0.311 0.000
M23.1 Discoid meniscus (congenital)
0.689 0.311 0.000
M23.0 Cystic meniscus
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.689 0.311 0.000
I46 Cardiac arrest
0.688 0.312 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.687 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.687 0.313 0.000
H53.0 Amblyopia ex anopsia
0.686 0.314 0.000
M35 Other systemic involvement of connective tissue
0.684 0.316 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
C91.1 Chronic lymphocytic leukaemia
0.684 0.316 0.000
T88.4 Failed or difficult intubation
0.683 0.317 0.000
M25.8 Other specified joint disorders
0.682 0.318 0.000
R46 Symptoms and signs involving appearance and behaviour
0.682 0.318 0.000
R43 Disturbances of smell and taste
0.682 0.318 0.000
J40-J47 Chronic lower respiratory diseases
0.682 0.318 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.681 0.319 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.679 0.320 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.679 0.321 0.000
M45-M49 Spondylopathies
0.678 0.321 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.678 0.321 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.678 0.322 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.678 0.322 0.000
M67 Other disorders of synovium and tendon
0.678 0.322 0.000
J32.4 Chronic pansinusitis
0.677 0.323 0.000
J32.3 Chronic sphenoidal sinusitis
0.677 0.323 0.000
J32.1 Chronic frontal sinusitis
0.677 0.323 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.677 0.323 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.677 0.323 0.000
S26 Injury of heart
0.677 0.323 0.000
S25 Injury of blood vessels of thorax
0.677 0.323 0.000
S24 Injury of nerves and spinal cord at thorax level
0.677 0.323 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.677 0.323 0.000
S21 Open wound of thorax
0.677 0.323 0.000
G20-G26 Extrapyramidal and movement disorders
0.677 0.323 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.676 0.324 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.675 0.325 0.000
A49 Bacterial infection of unspecified site
0.675 0.325 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.674 0.325 0.000
H27 Other disorders of lens
0.674 0.325 0.000
M31.6 Other giant cell arteritis
0.674 0.325 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.674 0.326 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.674 0.326 0.000
H74.0 Tympanosclerosis
0.674 0.326 0.000
L40-L45 Papulosquamous disorders
0.673 0.327 0.000
C22.0 Liver cell carcinoma
0.673 0.327 0.000
T79-T79 Certain early complications of trauma
0.673 0.327 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.672 0.327 0.000
H31 Other disorders of choroid
0.672 0.327 0.000
H30 Chorioretinal inflammation
0.672 0.327 0.000
R29.4 Clicking hip
0.672 0.328 0.000
R29.3 Abnormal posture
0.672 0.328 0.000
R29.2 Abnormal reflex
0.672 0.328 0.000
R29.1 Meningismus
0.672 0.328 0.000
R29.0 Tetany
0.672 0.328 0.000
R45.1 Restlessness and agitation
0.672 0.328 0.000
S50-S59 Injuries to the elbow and forearm
0.672 0.328 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.671 0.329 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.670 0.330 0.000
H52 Disorders of refraction and accommodation
0.670 0.330 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.670 0.330 0.000
J32.8 Other chronic sinusitis
0.669 0.330 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.669 0.331 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.668 0.331 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.668 0.331 0.000
H66.0 Acute suppurative otitis media
0.668 0.331 0.000
S22.2 Fracture of sternum
0.668 0.332 0.000
R59.1 Generalised enlarged lymph nodes
0.667 0.333 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.667 0.333 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.667 0.333 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.666 0.334 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.665 0.334 0.000
S98 Traumatic amputation of ankle and foot
0.665 0.334 0.000
S97 Crushing injury of ankle and foot
0.665 0.334 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.665 0.334 0.000
S95 Injury of blood vessels at ankle and foot level
0.665 0.334 0.000
S94 Injury of nerves at ankle and foot level
0.665 0.334 0.000
S90 Superficial injury of ankle and foot
0.665 0.334 0.000
C15.9 Oesophagus, unspecified
0.665 0.335 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.665 0.335 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.664 0.335 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.664 0.335 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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