TreeWAS – Variant ID: rs11191593

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I10 Essential (primary) hypertension	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.002	0.998
I20.9 Angina pectoris, unspecified	0.000	0.002	0.998
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.003	0.997
I25.2 Old myocardial infarction	0.000	0.007	0.993
I24 Other acute ischaemic heart diseases	0.000	0.042	0.958
I21 Acute myocardial infarction	0.000	0.052	0.948
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.085	0.915
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.129	0.871
I21.4 Acute subendocardial myocardial infarction	0.000	0.131	0.869
I24.8 Other forms of acute ischaemic heart disease	0.000	0.142	0.858
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.174	0.826
I20.1 Angina pectoris with documented spasm	0.000	0.197	0.803
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.206	0.794
I22 Subsequent myocardial infarction	0.000	0.226	0.774
I25.4 Coronary artery aneurysm	0.000	0.237	0.763
I25.3 Aneurysm of heart	0.000	0.282	0.718
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.292	0.708
I24.1 Dressler's syndrome	0.000	0.313	0.687
I10-I15 Hypertensive diseases	0.000	0.319	0.681
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.320	0.680
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.320	0.680
I25.5 Ischaemic cardiomyopathy	0.000	0.327	0.673
I23 Certain current complications following acute myocardial infarction	0.000	0.356	0.644
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.381	0.619
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.393	0.607
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.415	0.584
I21.9 Acute myocardial infarction, unspecified	0.000	0.433	0.567
I22.8 Subsequent myocardial infarction of other sites	0.000	0.442	0.557
Chapter IX Diseases of the circulatory system	0.000	0.459	0.541
I15 Secondary hypertension	0.000	0.466	0.534
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.493	0.506
I13 Hypertensive heart and renal disease	0.000	0.511	0.488
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.538	0.462
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.462
I20.8 Other forms of angina pectoris	0.000	0.545	0.454
I15.1 Hypertension secondary to other renal disorders	0.000	0.572	0.428
I11 Hypertensive heart disease	0.000	0.576	0.424
I23.8 Other current complications following acute myocardial infarction	0.000	0.611	0.389
I00-I02 Acute rheumatic fever	0.000	0.612	0.388
I15.9 Seconday hypertension, unspecified	0.000	0.617	0.383
I15.8 Other secondary hypertension	0.000	0.617	0.383
I15.2 Hypertension secondary to endocrine disorders	0.000	0.617	0.383
I15.0 Renovascular hypertension	0.000	0.617	0.383
I12 Hypertensive renal disease	0.000	0.626	0.374
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.650	0.350
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.650	0.350
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.650	0.350
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.650	0.350
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.720	0.279
I12.9 Hypertensive renal disease without renal failure	0.000	0.721	0.279
I02 Rheumatic chorea	0.000	0.722	0.278
I01 Rheumatic fever with heart involvement	0.000	0.722	0.278
I00 Rheumatic fever without mention of heart involvement	0.000	0.722	0.278
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.729	0.270
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.745	0.255
I60-I69 Cerebrovascular diseases	0.000	0.775	0.225
I99 Other and unspecified disorders of circulatory system	0.000	0.787	0.213
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.800	0.199
I01.8 Other acute rheumatic heart disease	0.000	0.800	0.199
I01.2 Acute rheumatic myocarditis	0.000	0.800	0.199
I01.1 Acute rheumatic endocarditis	0.000	0.800	0.199
I01.0 Acute rheumatic pericarditis	0.000	0.800	0.199
I02.9 Rheumatic chorea without heart involvement	0.000	0.800	0.199
I02.0 Rheumatic chorea with heart involvement	0.000	0.800	0.199
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.814	0.186
I62 Other nontraumatic intracranial haemorrhage	0.000	0.820	0.180
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.823	0.177
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.828	0.172
I69 Sequelae of cerebrovascular disease	0.000	0.836	0.164
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.839	0.161
I63 Cerebral infarction	0.000	0.841	0.159
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.000	0.842	0.158
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.842	0.157
K30 Dyspepsia	0.000	0.848	0.152
I05-I09 Chronic rheumatic heart diseases	0.001	0.853	0.146
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.854	0.146
I65.2 Occlusion and stenosis of carotid artery	0.000	0.857	0.143
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.857	0.143
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.858	0.142
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.862	0.137
I60 Subarachnoid haemorrhage	0.000	0.862	0.138
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.866	0.133
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.866	0.133
I98.0 Cardiovascular syphilis	0.000	0.866	0.133
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.868	0.132
I12.0 Hypertensive renal disease with renal failure	0.000	0.869	0.131
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.871	0.129
I62.1 Nontraumatic extradural haemorrhage	0.000	0.871	0.129
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.872	0.128
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.874	0.125
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.875	0.125
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.875	0.125
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.875	0.125
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.877	0.123
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.877	0.123
I65.1 Occlusion and stenosis of basilar artery	0.000	0.877	0.123
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.877	0.123
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.877	0.123
I63.8 Other cerebral infarction	0.000	0.878	0.122
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.882	0.118
I69.3 Sequelae of cerebral infarction	0.000	0.882	0.118
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.884	0.116
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.884	0.116
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.884	0.116
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.884	0.116
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.884	0.116
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.884	0.116
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.884	0.116
I67 Other cerebrovascular diseases	0.000	0.884	0.116
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.886	0.114
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.886	0.114
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.886	0.114
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.887	0.113
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.890	0.110
I60.8 Other subarachnoid haemorrhage	0.000	0.891	0.109
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.892	0.107
I06 Rheumatic aortic valve diseases	0.001	0.895	0.105
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.896	0.104
I09 Other rheumatic heart diseases	0.001	0.897	0.102
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.898	0.102
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.898	0.102
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.898	0.102
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.901	0.099
I97.0 Postcardiotomy syndrome	0.000	0.901	0.099
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.901	0.099
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.901	0.099
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.901	0.099
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.902	0.098
I28 Other diseases of pulmonary vessels	0.001	0.902	0.097
I67.1 Cerebral aneurysm, nonruptured	0.000	0.902	0.097
I07 Rheumatic tricuspid valve diseases	0.001	0.904	0.095
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.907	0.093
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.907	0.093
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.908	0.092
I67.2 Cerebral atherosclerosis	0.000	0.909	0.091
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.914	0.086
I68.0 Cerebral amyloid angiopathy	0.000	0.916	0.083
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.917	0.083
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.917	0.083
I67.5 Moyamoya disease	0.000	0.917	0.083
I67.4 Hypertensive encephalopathy	0.000	0.917	0.083
I67.3 Progressive vascular leukoencephalopathy	0.000	0.917	0.083
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.917	0.083
I97.1 Other functional disturbances following cardiac surgery	0.001	0.920	0.080
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.924	0.075
I06.8 Other rheumatic aortic valve diseases	0.001	0.924	0.075
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.924	0.075
I06.1 Rheumatic aortic insufficiency	0.001	0.924	0.075
I06.0 Rheumatic aortic stenosis	0.001	0.924	0.075
I09.8 Other specified rheumatic heart diseases	0.001	0.926	0.073
I09.2 Chronic rheumatic pericarditis	0.001	0.926	0.073
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.926	0.073
I09.0 Rheumatic myocarditis	0.001	0.926	0.073
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.927	0.072
I09.9 Rheumatic heart disease, unspecified	0.001	0.929	0.071
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.930	0.070
I28.1 Aneurysm of pulmonary artery	0.001	0.930	0.070
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.930	0.070
I07.9 Tricuspid valve disease, unspecified	0.001	0.931	0.069
I07.8 Other tricuspid valve diseases	0.001	0.931	0.069
I07.2 Tricuspid stenosis with insufficiency	0.001	0.931	0.069
I07.0 Tricuspid stenosis	0.001	0.931	0.069
I27 Other pulmonary heart diseases	0.001	0.931	0.068
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.932	0.068
I05 Rheumatic mitral valve diseases	0.001	0.932	0.067
R07.4 Chest pain, unspecified	0.000	0.934	0.066
I07.1 Tricuspid insufficiency	0.000	0.940	0.059
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.943	0.057
I26 Pulmonary embolism	0.000	0.944	0.056
I28.8 Other specified diseases of pulmonary vessels	0.001	0.945	0.054
I61 Intracerebral haemorrhage	0.002	0.946	0.052
K21 Gastro-oesophageal reflux disease	0.000	0.948	0.052
I27.8 Other specified pulmonary heart diseases	0.001	0.950	0.050
I27.1 Kyphoscoliotic heart disease	0.001	0.950	0.049
I05.8 Other mitral valve diseases	0.001	0.951	0.048
I05.1 Rheumatic mitral insufficiency	0.001	0.951	0.048
I27.0 Primary pulmonary hypertension	0.000	0.951	0.049
I05.9 Mitral valve disease, unspecified	0.001	0.954	0.046
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.954	0.045
M20.1 Hallux valgus (acquired)	0.045	0.955	0.000
I27.9 Pulmonary heart disease, unspecified	0.001	0.956	0.043
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.959	0.040
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.959	0.041
I77 Other disorders of arteries and arterioles	0.000	0.959	0.041
I05.2 Mitral stenosis with insufficiency	0.001	0.960	0.039
I67.8 Other specified cerebrovascular diseases	0.000	0.960	0.040
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.961	0.038
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.961	0.037
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.962	0.036
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.963	0.037
I61.8 Other intracerebral haemorrhage	0.001	0.964	0.035
I67.9 Cerebrovascular disease, unspecified	0.000	0.964	0.036
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.964	0.035
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.964	0.034
I05.0 Mitral stenosis	0.001	0.965	0.034
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.965	0.034
I72 Other aneurysm	0.000	0.966	0.034
I95 Hypotension	0.000	0.966	0.034
I77.1 Stricture of artery	0.000	0.966	0.034
I08 Multiple valve diseases	0.001	0.967	0.032
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.967	0.033
I79.1 Aortitis in diseases classified elsewhere	0.000	0.967	0.033
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.967	0.033
I70 Atherosclerosis	0.000	0.967	0.033
I74 Arterial embolism and thrombosis	0.000	0.969	0.031
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.969	0.031
I78 Diseases of capillaries	0.000	0.969	0.031
I77.5 Necrosis of artery	0.000	0.970	0.029
I77.4 Coeliac artery compression syndrome	0.000	0.970	0.029
I77.3 Arterial fibromuscular dysplasia	0.000	0.970	0.029
I77.2 Rupture of artery	0.000	0.970	0.029
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.970	0.030
I77.6 Arteritis, unspecified	0.000	0.971	0.029
I71 Aortic aneurysm and dissection	0.000	0.971	0.029
I72.0 Aneurysm of carotid artery	0.000	0.972	0.028
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.973	0.027
Z95.1 Presence of aortocoronary bypass graft	0.000	0.973	0.027
I74.5 Embolism and thrombosis of iliac artery	0.000	0.974	0.026
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.974	0.025
I77.8 Other specified disorders of arteries and arterioles	0.000	0.974	0.025
I72.8 Aneurysm of other specified arteries	0.000	0.974	0.025
I77.0 Arteriovenous fistula, acquired	0.000	0.975	0.025
K27 Peptic ulcer, site unspecified	0.000	0.975	0.025
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.975	0.024
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.975	0.024
I72.2 Aneurysm of renal artery	0.000	0.975	0.024
I72.1 Aneurysm of artery of upper extremity	0.000	0.975	0.024
I95.8 Other hypotension	0.000	0.975	0.024
I95.0 Idiopathic hypotension	0.000	0.976	0.024
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.976	0.024
I08.9 Multiple valve disease, unspecified	0.001	0.976	0.023
I70.9 Generalised and unspecified atherosclerosis	0.000	0.976	0.024
I70.8 Atherosclerosis of other arteries	0.000	0.976	0.024
I72.4 Aneurysm of artery of lower extremity	0.000	0.977	0.023
I70.1 Atherosclerosis of renal artery	0.000	0.977	0.023
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.977	0.023
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.977	0.023
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.977	0.023
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.978	0.022
I78.9 Disease of capillaries, unspecified	0.000	0.978	0.022
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.978	0.022
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.978	0.022
I08.8 Other multiple valve diseases	0.001	0.978	0.021
I72.9 Aneurysm of unspecified site	0.000	0.978	0.022
Z95.3 Presence of xenogenic heart valve	0.000	0.978	0.022
I78.8 Other diseases of capillaries	0.000	0.978	0.022
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.978	0.022
I74.8 Embolism and thrombosis of other arteries	0.000	0.978	0.021
I63.9 Cerebral infarction, unspecified	0.000	0.979	0.021
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.979	0.021
I71.0 Dissection of aorta [any part]	0.000	0.979	0.021
I70.0 Atherosclerosis of aorta	0.000	0.979	0.021
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.979	0.021
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.979	0.021
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.979	0.021
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.979	0.021
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.979	0.021
K28 Gastrojejunal ulcer	0.000	0.979	0.021
R07 Pain in throat and chest	0.000	0.980	0.020
I27.2 Other secondary pulmonary hypertension	0.001	0.980	0.019
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.980	0.020
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.980	0.019
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.981	0.019
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.981	0.019
Z95.4 Presence of other heart-valve replacement	0.000	0.981	0.019
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.982	0.018
K27.7 Chronic without haemorrhage or perforation	0.000	0.982	0.018
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.982	0.018
K27.5 Chronic or unspecified with perforation	0.000	0.982	0.018
K27.4 Chronic or unspecified with haemorrhage	0.000	0.982	0.018
K27.3 Acute without haemorrhage or perforation	0.000	0.982	0.018
K27.2 Acute with both haemorrhage and perforation	0.000	0.982	0.018
K27.1 Acute with perforation	0.000	0.982	0.018
K27.0 Acute with haemorrhage	0.000	0.982	0.018
I95.2 Hypotension due to drugs	0.000	0.982	0.018
Z95.2 Presence of prosthetic heart valve	0.000	0.982	0.018
M25.46 Effusion of joint (Lower leg)	0.017	0.983	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.983	0.017
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.983	0.017
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.983	0.017
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.983	0.017
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.983	0.016
K26 Duodenal ulcer	0.000	0.984	0.016
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.984	0.016
R07.0 Pain in throat	0.000	0.984	0.016
I72.3 Aneurysm of iliac artery	0.001	0.984	0.015
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.000	0.984	0.015
K23.1 Megaoesophagus in Chagas' disease	0.000	0.984	0.015
K23.0 Tuberculous oesophagitis	0.000	0.984	0.015
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.984	0.015
K62.0 Anal polyp	0.015	0.985	0.000
K28.7 Chronic without haemorrhage or perforation	0.000	0.985	0.015
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.985	0.015
K28.5 Chronic or unspecified with perforation	0.000	0.985	0.015
K28.4 Chronic or unspecified with haemorrhage	0.000	0.985	0.015
K28.3 Acute without haemorrhage or perforation	0.000	0.985	0.015
K28.2 Acute with both haemorrhage and perforation	0.000	0.985	0.015
K28.1 Acute with perforation	0.000	0.985	0.015
K28.0 Acute with haemorrhage	0.000	0.985	0.015
R07.2 Precordial pain	0.000	0.985	0.015
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.985	0.014
I78.1 Naevus, nonneoplastic	0.000	0.985	0.015
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.985	0.015
K26.3 Acute without haemorrhage or perforation	0.000	0.985	0.015
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.985	0.014
R07.3 Other chest pain	0.000	0.985	0.015
I30-I52 Other forms of heart disease	0.000	0.986	0.014
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.014	0.986	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.986	0.014
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.986	0.011
M20 Acquired deformities of fingers and toes	0.014	0.986	0.000
I73 Other peripheral vascular diseases	0.000	0.987	0.013
I45 Other conduction disorders	0.000	0.987	0.013
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.987	0.013
I45.1 Other and unspecified right bundle-branch block	0.000	0.987	0.013
Z95.0 Presence of cardiac pacemaker	0.000	0.987	0.013
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.987	0.013
K26.5 Chronic or unspecified with perforation	0.000	0.987	0.013
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.987	0.012
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.013	0.987	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.988	0.012
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.988	0.012
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.988	0.012
K26.2 Acute with both haemorrhage and perforation	0.000	0.988	0.012
I44.1 Atrioventricular block, second degree	0.000	0.988	0.012
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.012	0.988	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.988	0.012
I50.1 Left ventricular failure	0.000	0.988	0.012
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.011	0.988	0.000
I50 Heart failure	0.000	0.989	0.011
I44.7 Left bundle-branch block, unspecified	0.000	0.989	0.011
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.011	0.989	0.000
M20.3 Other deformity of hallux (acquired)	0.011	0.989	0.000
K26.0 Acute with haemorrhage	0.000	0.989	0.011
I37 Pulmonary valve disorders	0.000	0.989	0.011
I45.6 Preexcitation syndrome	0.000	0.989	0.011
K26.1 Acute with perforation	0.000	0.989	0.010
I36 Nonrheumatic tricuspid valve disorders	0.000	0.989	0.010
I52 Other heart disorders in diseases classified elsewhere	0.000	0.990	0.010
I48 Atrial fibrillation and flutter	0.000	0.990	0.010
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.990	0.010
I41 Myocarditis in diseases classified elsewhere	0.000	0.990	0.010
I40 Acute myocarditis	0.000	0.990	0.010
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.990	0.010
I32 Pericarditis in diseases classified elsewhere	0.000	0.990	0.010
M25.4 Effusion of joint	0.010	0.990	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.010	0.990	0.000
I45.8 Other specified conduction disorders	0.000	0.990	0.010
I45.2 Bifascicular block	0.000	0.990	0.010
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.990	0.010
I45.0 Right fascicular block	0.000	0.990	0.010
I45.3 Trifascicular block	0.000	0.990	0.010
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.010	0.990	0.000
M20.4 Other hammer toe(s) (acquired)	0.010	0.990	0.000
I45.4 Nonspecific intraventricular block	0.000	0.991	0.009
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.009	0.991	0.000
I45.9 Conduction disorder, unspecified	0.000	0.991	0.009
I46 Cardiac arrest	0.000	0.991	0.009
I44.5 Left posterior fascicular block	0.000	0.991	0.009
I73.8 Other specified peripheral vascular diseases	0.000	0.991	0.009
I44.6 Other and unspecified fascicular block	0.000	0.991	0.009
M20.2 Hallux rigidus	0.009	0.991	0.000
I38 Endocarditis, valve unspecified	0.000	0.991	0.009
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
I33 Acute and subacute endocarditis	0.000	0.991	0.009
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.009	0.991	0.000
R07.1 Chest pain on breathing	0.000	0.991	0.008
I30 Acute pericarditis	0.000	0.991	0.008
I44.3 Other and unspecified atrioventricular block	0.000	0.991	0.008
I37.1 Pulmonary valve insufficiency	0.000	0.992	0.008
M65.9 Synovitis and tenosynovitis, unspecified	0.008	0.992	0.000
I45.5 Other specified heart block	0.000	0.992	0.008
M20-M25 Other joint disorders	0.008	0.992	0.000
I44.0 Atrioventricular block, first degree	0.000	0.992	0.008
M22.8 Other disorders of patella	0.008	0.992	0.000
I49 Other cardiac arrhythmias	0.000	0.992	0.008
I37.9 Pulmonary valve disorder, unspecified	0.000	0.992	0.008
I37.8 Other pulmonary valve disorders	0.000	0.992	0.008
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.992	0.008
I37.0 Pulmonary valve stenosis	0.000	0.992	0.008
M20.6 Acquired deformity of toe(s), unspecified	0.008	0.992	0.000
M25.40 Effusion of joint (Multiple sites)	0.008	0.992	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.992	0.008
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.008	0.992	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.008	0.992	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.992	0.008
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.992	0.008
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.992	0.008
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.992	0.008
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.992	0.008
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.992	0.008
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.992	0.008
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I40.9 Acute myocarditis, unspecified	0.000	0.992	0.008
I40.8 Other acute myocarditis	0.000	0.992	0.008
I40.1 Isolated myocarditis	0.000	0.992	0.008
I40.0 Infective myocarditis	0.000	0.992	0.008
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.992	0.008
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.992	0.008
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.992	0.008
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.992	0.008
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.992	0.008
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.992	0.008
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.992	0.008
I48.4 Atypical atrial flutter	0.000	0.992	0.008
I48.3 Typical atrial flutter	0.000	0.992	0.008
I48.2 Chronic atrial fibrillation	0.000	0.992	0.008
I48.1 Persistent atrial fibrillation	0.000	0.992	0.008
I48.0 Paroxysmal atrial fibrillation	0.000	0.992	0.008
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.992	0.008
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.992	0.008
M22 Disorders of patella	0.008	0.992	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.992	0.008
I08.0 Disorders of both mitral and aortic valves	0.002	0.992	0.006
M20.5 Other deformities of toe(s) (acquired)	0.008	0.992	0.000
M21 Other acquired deformities of limbs	0.008	0.992	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.992	0.008
M65.4 Radial styloid tenosynovitis [de Quervain]	0.008	0.992	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.992	0.008
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.008	0.992	0.000
M25.49 Effusion of joint (Site unspecified)	0.007	0.992	0.000
M25.48 Effusion of joint (Other)	0.007	0.992	0.000
M25.44 Effusion of joint (Hand)	0.007	0.992	0.000
M25.43 Effusion of joint (Forearm)	0.007	0.992	0.000
M25.42 Effusion of joint (Upper arm)	0.007	0.992	0.000
M25.41 Effusion of joint (Shoulder region)	0.007	0.992	0.000
M21.0 Valgus deformity, not elsewhere classified	0.007	0.992	0.000
M25 Other joint disorders, not elsewhere classified	0.008	0.992	0.000
I44.4 Left anterior fascicular block	0.000	0.993	0.007
I44.2 Atrioventricular block, complete	0.000	0.993	0.007
I46.0 Cardiac arrest with successful resuscitation	0.000	0.993	0.007
I95.1 Orthostatic hypotension	0.000	0.993	0.007
M25.3 Other instability of joint	0.007	0.993	0.000
M65 Synovitis and tenosynovitis	0.007	0.993	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.007	0.993	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.007	0.993	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.993	0.007
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.007	0.993	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.007	0.993	0.000
M22.2 Patellofemoral disorders	0.007	0.993	0.000
I46.1 Sudden cardiac death, so described	0.000	0.993	0.007
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.007	0.993	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.993	0.007
I33.9 Acute endocarditis, unspecified	0.000	0.993	0.007
M25.37 Other instability of joint (Ankle and foot)	0.007	0.993	0.000
I31 Other diseases of pericardium	0.000	0.993	0.007
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.007	0.993	0.000
M21.3 Wrist or foot drop (acquired)	0.006	0.993	0.000
I50.9 Heart failure, unspecified	0.000	0.993	0.007
M35 Other systemic involvement of connective tissue	0.007	0.993	0.000
I30.8 Other forms of acute pericarditis	0.000	0.994	0.006
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.994	0.006
I49.9 Cardiac arrhythmia, unspecified	0.000	0.994	0.006
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.006	0.994	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.006	0.994	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.006	0.994	0.000
K31 Other diseases of stomach and duodenum	0.000	0.994	0.006
M33 Dermatopolymyositis	0.006	0.994	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.006	0.994	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.994	0.006
I35.9 Aortic valve disorder, unspecified	0.000	0.994	0.006
I49.2 Junctional premature depolarisation	0.000	0.994	0.006
M35.0 Sicca syndrome [Sjogren]	0.006	0.994	0.000
M32 Systemic lupus erythematosus	0.006	0.994	0.000
M30 Polyarteritis nodosa and related conditions	0.006	0.994	0.000
I42 Cardiomyopathy	0.000	0.994	0.006
M20.0 Deformity of finger(s)	0.006	0.994	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.006	0.994	0.000
I30.1 Infective pericarditis	0.000	0.994	0.006
M34 Systemic sclerosis	0.006	0.994	0.000
I35.0 Aortic (valve) stenosis	0.000	0.994	0.006
M25.34 Other instability of joint (Hand)	0.006	0.994	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.006	0.994	0.000
M22.1 Recurrent subluxation of patella	0.006	0.994	0.000
M22.9 Disorder of patella, unspecified	0.006	0.994	0.000
M22.0 Recurrent dislocation of patella	0.006	0.994	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.006	0.994	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.006	0.994	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations