TreeWAS – Variant ID: rs11247915

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.060	0.940	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.955	0.045
D36.7 Other specified sites	0.000	0.956	0.044
D36 Benign neoplasm of other and unspecified sites	0.000	0.956	0.044
D36.0 Lymph nodes	0.000	0.961	0.039
D36.9 Benign neoplasm of unspecified site	0.000	0.968	0.032
R00.1 Bradycardia, unspecified	0.021	0.979	0.000
E10.1 With ketoacidosis	0.000	0.988	0.012
S02.60 Fracture of mandible (closed)	0.012	0.988	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.989	0.011
E10.2 With renal complications	0.000	0.990	0.010
E10.9 Without complications	0.000	0.990	0.010
E10.5 With peripheral circulatory complications	0.000	0.990	0.010
E10.8 With unspecified complications	0.000	0.990	0.009
K09.0 Developmental odontogenic cysts	0.000	0.991	0.009
S02.6 Fracture of mandible	0.009	0.991	0.000
E10.7 With multiple complications	0.000	0.991	0.009
I24 Other acute ischaemic heart diseases	0.009	0.991	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.992	0.008
H72.0 Central perforation of tympanic membrane	0.008	0.992	0.000
E10.4 With neurological complications	0.000	0.993	0.007
E10.6 With other specified complications	0.000	0.993	0.007
N87.1 Moderate cervical dysplasia	0.007	0.993	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
E10.3 With ophthalmic complications	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.007
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
S02.61 Fracture of mandible (open)	0.006	0.993	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.993	0.007
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.993	0.007
S02.20 Fracture of nasal bones (closed)	0.007	0.993	0.000
C53.9 Cervix uteri, unspecified	0.000	0.993	0.007
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.994	0.006
S02.2 Fracture of nasal bones	0.006	0.994	0.000
I24.1 Dressler's syndrome	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.994	0.006
S02 Fracture of skull and facial bones	0.006	0.994	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.006	0.994	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.994	0.006
S02.5 Fracture of tooth	0.006	0.994	0.000
S02.50 Fracture of tooth (closed)	0.006	0.994	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.994	0.006
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.994	0.006
T36 Poisoning by systemic antibiotics	0.000	0.994	0.006
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.994	0.006
S02.7 Multiple fractures involving skull and facial bones	0.005	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.994	0.005
I24.8 Other forms of acute ischaemic heart disease	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.995	0.005
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.995	0.005
T40.2 Other opioids	0.000	0.995	0.005
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.995	0.005
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.995	0.005
T46.1 Calcium-channel blockers	0.000	0.995	0.005
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.995	0.005
T50.8 Diagnostic agents	0.000	0.995	0.005
N87 Dysplasia of cervix uteri	0.005	0.995	0.000
E10.0 With coma	0.000	0.995	0.005
T50.7 Analeptics and opioid receptor antagonists	0.000	0.995	0.005
T50.5 Appetite depressants	0.000	0.995	0.005
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.995	0.005
T50.0 Mineralocorticoids and their antagonists	0.000	0.995	0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.995	0.005
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.995	0.005
T38.0 Glucocorticoids and synthetic analogues	0.000	0.995	0.005
S02.70 Multiple fractures involving skull and facial bones (closed)	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.995	0.005
T46.7 Peripheral vasodilators	0.000	0.995	0.005
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.995	0.005
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.995	0.005
S02.21 Fracture of nasal bones (open)	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.995	0.005
T38.9 Other and unspecified hormone antagonists	0.000	0.995	0.005
T38.7 Androgens and anabolic congeners	0.000	0.995	0.005
T38.5 Other oestrogens and progestogens	0.000	0.995	0.005
T38.4 Oral contraceptives	0.000	0.995	0.005
T38.2 Antithyroid drugs	0.000	0.995	0.005
T36.0 Penicillins	0.000	0.995	0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.995	0.005
T50.1 Loop [high-ceiling] diuretics	0.000	0.995	0.005
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.995	0.005
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.995	0.005
S02.9 Fracture of skull and facial bones, part unspecified	0.005	0.995	0.000
S02.1 Fracture of base of skull	0.005	0.995	0.000
S02.8 Fractures of other skull and facial bones	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.995	0.005
T36.3 Macrolides	0.000	0.995	0.005
T39.0 Salicylates	0.000	0.995	0.005
H72 Perforation of tympanic membrane	0.005	0.995	0.000
S02.51 Fracture of tooth (open)	0.004	0.995	0.000
T48.5 Anti-common-cold drugs	0.000	0.995	0.004
T36.4 Tetracyclines	0.000	0.996	0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.996	0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.004
H02.9 Disorder of eyelid, unspecified	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
T36.8 Other systemic antibiotics	0.000	0.996	0.004
T36.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
T36.6 Rifamycins	0.000	0.996	0.004
T36.5 Aminoglycosides	0.000	0.996	0.004
T36.2 Chloramphenicol group	0.000	0.996	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.996	0.004
S02.71 Multiple fractures involving skull and facial bones (open)	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.004
Z81.8 Family history of other mental and behavioural disorders	0.004	0.996	0.000
S02.0 Fracture of vault of skull	0.004	0.996	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.996	0.004
T40.8 Lysergide [LSD]	0.000	0.996	0.004
T40.7 Cannabis (derivatives)	0.000	0.996	0.004
T40.5 Cocaine	0.000	0.996	0.004
T40.3 Methadone	0.000	0.996	0.004
T40.0 Opium	0.000	0.996	0.004
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.996	0.004
T48.4 Expectorants	0.000	0.996	0.004
T48.3 Antitussives	0.000	0.996	0.004
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.996	0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.996	0.004
T48.0 Oxytocic drugs	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.000	0.996	0.004
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.004
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.004
T47.7 Emetics	0.000	0.996	0.004
T47.5 Digestants	0.000	0.996	0.004
T47.3 Saline and osmotic laxatives	0.000	0.996	0.004
N87.0 Mild cervical dysplasia	0.004	0.996	0.000
J43.9 Emphysema, unspecified	0.000	0.996	0.004
T40.1 Heroin	0.000	0.996	0.004
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.000	0.996	0.004
Y85.9 Sequelae of other and unspecified transport accidents	0.004	0.996	0.000
T41.5 Therapeutic gases	0.000	0.996	0.003
T41.4 Anaesthetic, unspecified	0.000	0.996	0.003
T41.3 Local anaesthetics	0.000	0.996	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.996	0.003
T41.1 Intravenous anaesthetics	0.000	0.996	0.003
T41.0 Inhaled anaesthetics	0.000	0.996	0.003
T47.2 Stimulant laxatives	0.000	0.996	0.003
T49.9 Topical agent, unspecified	0.000	0.996	0.003
T49.8 Other topical agents	0.000	0.996	0.003
T49.7 Dental drugs, topically applied	0.000	0.996	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.003
T49.2 Local astringents and local detergents	0.000	0.996	0.003
T49.1 Antipruritics	0.000	0.996	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.003
T47.4 Other laxatives	0.000	0.996	0.003
S02.3 Fracture of orbital floor	0.003	0.996	0.000
Y85.0 Sequelae of motor-vehicle accident	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.996	0.004
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.996	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.004	0.996	0.000
S02.81 Fractures of other skull and facial bones (open)	0.003	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.996	0.000
E22.1 Hyperprolactinaemia	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.003
S52.00 Fracture of upper end of ulna (closed)	0.004	0.996	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.996	0.003
T39.2 Pyrazolone derivatives	0.000	0.996	0.003
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
S02.01 Fracture of vault of skull (open)	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.003
T25 Burn and corrosion of ankle and foot	0.000	0.997	0.003
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.003
N87.2 Severe cervical dysplasia, not elsewhere classified	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
I77.1 Stricture of artery	0.000	0.997	0.003
S02.11 Fracture of base of skull (open)	0.003	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
Y85 Sequelae of transport accidents	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
T20.2 Burn of second degree of head and neck	0.000	0.997	0.003
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
S02.31 Fracture of orbital floor (open)	0.003	0.997	0.000
S63.6 Sprain and strain of finger(s)	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
T21 Burn and corrosion of trunk	0.000	0.997	0.003
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T20.3 Burn of third degree of head and neck	0.000	0.997	0.003
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.997	0.003
S51.8 Open wound of other parts of forearm	0.000	0.997	0.003
S02.00 Fracture of vault of skull (closed)	0.003	0.997	0.000
T45.5 Anticoagulants	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.997	0.003
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
H70 Mastoiditis and related conditions	0.003	0.997	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T20.7 Corrosion of third degree of head and neck	0.000	0.997	0.003
T20.6 Corrosion of second degree of head and neck	0.000	0.997	0.003
T20.5 Corrosion of first degree of head and neck	0.000	0.997	0.003
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.997	0.003
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.997	0.000
J32.9 Chronic sinusitis, unspecified	0.003	0.997	0.000
T25.7 Corrosion of third degree of ankle and foot	0.000	0.997	0.002
T25.6 Corrosion of second degree of ankle and foot	0.000	0.997	0.002
T25.5 Corrosion of first degree of ankle and foot	0.000	0.997	0.002
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.997	0.002
T25.1 Burn of first degree of ankle and foot	0.000	0.997	0.002
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
R02 Gangrene, not elsewhere classified	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.997	0.000
H71 Cholesteatoma of middle ear	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.997	0.003
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.997	0.000
S51.0 Open wound of elbow	0.000	0.997	0.003
T25.3 Burn of third degree of ankle and foot	0.000	0.997	0.002
T25.2 Burn of second degree of ankle and foot	0.000	0.997	0.002
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
T20.1 Burn of first degree of head and neck	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.000	0.998	0.002
N32.3 Diverticulum of bladder	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.000	0.998	0.002
E25 Adrenogenital disorders	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
Y04.8 Other specified place	0.000	0.998	0.002
E23.0 Hypopituitarism	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.998	0.002
T23.6 Corrosion of second degree of wrist and hand	0.000	0.998	0.002
T23.5 Corrosion of first degree of wrist and hand	0.000	0.998	0.002
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
B34.9 Viral infection, unspecified	0.002	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.000	0.998	0.002
T21.6 Corrosion of second degree of trunk	0.000	0.998	0.002
T21.5 Corrosion of first degree of trunk	0.000	0.998	0.002
T21.4 Corrosion of unspecified degree of trunk	0.000	0.998	0.002
T21.3 Burn of third degree of trunk	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
L23 Allergic contact dermatitis	0.002	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
I20.1 Angina pectoris with documented spasm	0.002	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
T23.1 Burn of first degree of wrist and hand	0.000	0.998	0.002
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.000	0.998	0.002
M24.2 Disorder of ligament	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
M54.57 Low back pain (Lumbosacral region)	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.002	0.998	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.002	0.998	0.000
X68.9 Unspecified place	0.000	0.998	0.002
E32 Diseases of thymus	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.998	0.002
H02.0 Entropion and trichiasis of eyelid	0.000	0.998	0.002
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
S51 Open wound of forearm	0.000	0.998	0.002
C53.8 Overlapping lesion of cervix uteri	0.000	0.998	0.002
C53.1 Exocervix	0.000	0.998	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
D39.1 Ovary	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
K59.1 Functional diarrhoea	0.002	0.998	0.000
T42.1 Iminostilbenes	0.000	0.998	0.002
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
L27.2 Dermatitis due to ingested food	0.002	0.998	0.000
K59.3 Megacolon, not elsewhere classified	0.002	0.998	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.002	0.998	0.000
L27.8 Dermatitis due to other substances taken internally	0.002	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.998	0.002
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
I77 Other disorders of arteries and arterioles	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.000	0.998	0.002
M24.21 Disorder of ligament (Shoulder region)	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
L23.8 Allergic contact dermatitis due to other agents	0.002	0.998	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.002	0.998	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.002	0.998	0.000
L23.4 Allergic contact dermatitis due to dyes	0.002	0.998	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.002	0.998	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.002	0.998	0.000
L23.0 Allergic contact dermatitis due to metals	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
E20 Hypoparathyroidism	0.002	0.998	0.000
Z81 Family history of mental and behavioural disorders	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
M24.29 Disorder of ligament (Site unspecified)	0.000	0.998	0.002
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.998	0.002
M24.22 Disorder of ligament (Upper arm)	0.000	0.998	0.002
M24.20 Disorder of ligament (Multiple sites)	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
L20 Atopic dermatitis	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S51.7 Multiple open wounds of forearm	0.000	0.998	0.002
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.001	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.998	0.000
E30.8 Other disorders of puberty	0.001	0.998	0.000
E30.1 Precocious puberty	0.001	0.998	0.000
E30.0 Delayed puberty	0.001	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
T42.3 Barbiturates	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
L20.8 Other atopic dermatitis	0.002	0.998	0.000
J93 Pneumothorax	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
I77.5 Necrosis of artery	0.000	0.998	0.002
I77.4 Coeliac artery compression syndrome	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.002
N02.9 Unspecified	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.001
Y04.5 Trade and service area	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.001	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.001	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.001	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
Z81.4 Family history of other substance abuse	0.001	0.998	0.000
Z81.3 Family history of other psychoactive substance abuse	0.001	0.998	0.000
Z81.2 Family history of tobacco abuse	0.001	0.998	0.000
Z81.0 Family history of mental retardation	0.001	0.998	0.000
N02 Recurrent and persistent haematuria	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
K80.4 Calculus of bile duct with cholecystitis	0.000	0.998	0.002
N02.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
J43 Emphysema	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
C53.0 Endocervix	0.000	0.998	0.001
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.998	0.002
L20.0 Besnier's prurigo	0.001	0.998	0.000
N02.8 Other	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z81.1 Family history of alcohol abuse	0.001	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.998	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.002	0.998	0.000
L20-L30 Dermatitis and eczema	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.000	0.998	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations