TreeWAS – Variant ID: rs11256193

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001	0.000
B95-B98 Bacterial, viral and other infectious agents	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.997	0.003	0.000
I30-I52 Other forms of heart disease	0.996	0.004	0.000
J45 Asthma	0.995	0.005	0.000
Chapter II Neoplasms	0.992	0.008	0.000
Chapter VII Diseases of the eye and adnexa	0.992	0.008	0.000
Chapter IX Diseases of the circulatory system	0.991	0.009	0.000
J40-J47 Chronic lower respiratory diseases	0.986	0.014	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.983	0.017	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.974	0.026	0.000
Chapter X Diseases of the respiratory system	0.973	0.027	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.027	0.973
C44 Other malignant neoplasms of skin	0.000	0.028	0.972
C44.4 Skin of scalp and neck	0.000	0.029	0.971
T36-T50 Poisoning by drugs, medicaments and biological substances	0.969	0.031	0.000
C64-C68 Malignant neoplasms of urinary tract	0.969	0.031	0.000
I47 Paroxysmal tachycardia	0.961	0.039	0.000
C67 Malignant neoplasm of bladder	0.961	0.039	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.959	0.041	0.000
I34 Nonrheumatic mitral valve disorders	0.953	0.047	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.942	0.058	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.940	0.060	0.000
H30-H36 Disorders of choroid and retina	0.937	0.063	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.937	0.063	0.000
Chapter XXII Codes for special purposes	0.932	0.068	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.931	0.069	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.931	0.069	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.928	0.072	0.000
H04 Disorders of lachrymal system	0.924	0.076	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.919	0.081	0.000
I50 Heart failure	0.916	0.084	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.913	0.087	0.000
I47.2 Ventricular tachycardia	0.911	0.089	0.000
J45.0 Predominantly allergic asthma	0.908	0.092	0.000
H34 Retinal vascular occlusions	0.906	0.094	0.000
C44.5 Skin of trunk	0.000	0.096	0.904
J46 Status asthmaticus	0.904	0.096	0.000
I46 Cardiac arrest	0.903	0.097	0.000
I49 Other cardiac arrhythmias	0.902	0.098	0.000
H40-H42 Glaucoma	0.898	0.102	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.896	0.104	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.893	0.107	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.885	0.115	0.000
I34.0 Mitral (valve) insufficiency	0.882	0.118	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.876	0.124	0.000
S90-S99 Injuries to the ankle and foot	0.876	0.124	0.000
I51 Complications and ill-defined descriptions of heart disease	0.875	0.125	0.000
I35 Nonrheumatic aortic valve disorders	0.875	0.125	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.095	0.125	0.780
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.874	0.126	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.873	0.127	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.870	0.130	0.000
I50.1 Left ventricular failure	0.868	0.132	0.000
C67.1 Dome of bladder	0.867	0.133	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.867	0.133	0.000
C15-C26 Malignant neoplasms of digestive organs	0.864	0.136	0.000
C67.5 Bladder neck	0.860	0.140	0.000
H04.1 Other disorders of lachrymal gland	0.857	0.143	0.000
J44 Other chronic obstructive pulmonary disease	0.857	0.143	0.000
C77.0 Lymph nodes of head, face and neck	0.856	0.144	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.856	0.144	0.000
H34.8 Other retinal vascular occlusions	0.853	0.147	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.849	0.151	0.000
I42 Cardiomyopathy	0.848	0.152	0.000
C01 Malignant neoplasm of base of tongue	0.847	0.153	0.000
C77.1 Intrathoracic lymph nodes	0.843	0.157	0.000
I46.0 Cardiac arrest with successful resuscitation	0.842	0.158	0.000
B65-B83 Helminthiases	0.841	0.159	0.000
L05 Pilonidal cyst	0.837	0.163	0.000
C18 Malignant neoplasm of colon	0.836	0.164	0.000
B15-B19 Viral hepatitis	0.834	0.166	0.000
U80 Agent resistant to penicillin and related antibiotics	0.833	0.167	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.832	0.167	0.000
H40 Glaucoma	0.831	0.169	0.000
Q50-Q56 Congenital malformations of genital organs	0.829	0.171	0.000
C77.2 Intra-abdominal lymph nodes	0.829	0.171	0.000
H04.2 Epiphora	0.827	0.173	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.823	0.177	0.000
I44 Atrioventricular and left bundle-branch block	0.822	0.178	0.000
S40-S49 Injuries to the shoulder and upper arm	0.818	0.182	0.000
S70-S79 Injuries to the hip and thigh	0.814	0.186	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.813	0.187	0.000
I34.1 Mitral (valve) prolapse	0.812	0.188	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.811	0.189	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.810	0.190	0.000
C67.6 Ureteric orifice	0.809	0.191	0.000
C18.7 Sigmoid colon	0.808	0.192	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.802	0.198	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.801	0.199	0.000
I49.0 Ventricular fibrillation and flutter	0.800	0.200	0.000
S60-S69 Injuries to the wrist and hand	0.798	0.202	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.795	0.205	0.000
L05.9 Pilonidal cyst without abscess	0.794	0.206	0.000
T93 Sequelae of injuries of lower limb	0.791	0.209	0.000
I44.2 Atrioventricular block, complete	0.788	0.212	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.788	0.212	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.788	0.212	0.000
H20 Iridocyclitis	0.786	0.214	0.000
C77.4 Inguinal and lower limb lymph nodes	0.784	0.216	0.000
H04.8 Other disorders of lachrymal system	0.784	0.216	0.000
Q60-Q64 Congenital malformations of the urinary system	0.784	0.216	0.000
H55-H59 Other disorders of eye and adnexa	0.783	0.217	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.781	0.219	0.000
I51.8 Other ill-defined heart diseases	0.781	0.219	0.000
U80.1 Methicillin resistant agent	0.778	0.222	0.000
I35.0 Aortic (valve) stenosis	0.778	0.222	0.000
Q66 Congenital deformities of feet	0.778	0.222	0.000
L03 Cellulitis	0.777	0.223	0.000
C65 Malignant neoplasm of renal pelvis	0.775	0.225	0.000
S20-S29 Injuries to the thorax	0.774	0.226	0.000
C67.3 Anterior wall of bladder	0.774	0.226	0.000
I49.3 Ventricular premature depolarisation	0.772	0.228	0.000
C67.9 Bladder, unspecified	0.771	0.229	0.000
C77.9 Lymph node, unspecified	0.768	0.232	0.000
S10-S19 Injuries to the neck	0.767	0.233	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.765	0.235	0.000
T66-T78 Other and unspecified effects of external causes	0.762	0.238	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.761	0.239	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.760	0.240	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.759	0.241	0.000
I47.1 Supraventricular tachycardia	0.758	0.242	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.757	0.243	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.757	0.243	0.000
H18 Other disorders of cornea	0.757	0.243	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.754	0.246	0.000
T40.2 Other opioids	0.751	0.249	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.750	0.250	0.000
T92 Sequelae of injuries of upper limb	0.750	0.250	0.000
C18.9 Colon, unspecified	0.749	0.251	0.000
H10-H13 Disorders of conjunctiva	0.748	0.252	0.000
H34.2 Other retinal artery occlusions	0.746	0.254	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.746	0.254	0.000
H36 Retinal disorders in diseases classified elsewhere	0.745	0.255	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.744	0.256	0.000
B99-B99 Other infectious diseases	0.743	0.257	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.743	0.257	0.000
I38 Endocarditis, valve unspecified	0.743	0.257	0.000
Q00-Q07 Congenital malformations of the nervous system	0.741	0.259	0.000
C67.0 Trigone of bladder	0.740	0.260	0.000
H40.0 Glaucoma suspect	0.740	0.260	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.739	0.261	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.739	0.261	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.738	0.262	0.000
C10 Malignant neoplasm of oropharynx	0.738	0.262	0.000
S62 Fracture at wrist and hand level	0.737	0.263	0.000
S70 Superficial injury of hip and thigh	0.737	0.263	0.000
I35.1 Aortic (valve) insufficiency	0.736	0.264	0.000
H34.1 Central retinal artery occlusion	0.734	0.266	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.734	0.266	0.000
H40.9 Glaucoma, unspecified	0.733	0.267	0.000
L03.2 Cellulitis of face	0.730	0.270	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.728	0.272	0.000
B80 Enterobiasis	0.728	0.272	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.728	0.272	0.000
C51-C58 Malignant neoplasms of female genital organs	0.726	0.274	0.000
C43 Malignant melanoma of skin	0.018	0.274	0.707
I51.6 Cardiovascular disease, unspecified	0.723	0.277	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.722	0.278	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.722	0.278	0.000
C25 Malignant neoplasm of pancreas	0.722	0.278	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.722	0.278	0.000
T90 Sequelae of injuries of head	0.719	0.280	0.000
C67.2 Lateral wall of bladder	0.719	0.281	0.000
I50.0 Congestive heart failure	0.718	0.282	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.718	0.282	0.000
L03.0 Cellulitis of finger and toe	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
L05.0 Pilonidal cyst with abscess	0.717	0.283	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283	0.000
B50-B64 Protozoal diseases	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A65-A69 Other spirochaetal diseases	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
A15-A19 Tuberculosis	0.717	0.283	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.284	0.000
B35-B49 Mycoses	0.716	0.284	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.715	0.285	0.000
I52 Other heart disorders in diseases classified elsewhere	0.714	0.286	0.000
I48 Atrial fibrillation and flutter	0.714	0.286	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.714	0.286	0.000
I41 Myocarditis in diseases classified elsewhere	0.714	0.286	0.000
I40 Acute myocarditis	0.714	0.286	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.714	0.286	0.000
I32 Pericarditis in diseases classified elsewhere	0.714	0.286	0.000
J45.8 Mixed asthma	0.714	0.286	0.000
J45.1 Nonallergic asthma	0.714	0.286	0.000
C09 Malignant neoplasm of tonsil	0.713	0.287	0.000
I49.8 Other specified cardiac arrhythmias	0.713	0.287	0.000
I42.0 Dilated cardiomyopathy	0.713	0.287	0.000
C67.4 Posterior wall of bladder	0.712	0.288	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.712	0.288	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.712	0.288	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.711	0.289	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.289	0.000
H40.2 Primary angle-closure glaucoma	0.711	0.289	0.000
I00-I02 Acute rheumatic fever	0.710	0.290	0.000
Q66.8 Other congenital deformities of feet	0.708	0.292	0.000
C77.5 Intrapelvic lymph nodes	0.707	0.293	0.000
J41 Simple and mucopurulent chronic bronchitis	0.707	0.293	0.000
H01 Other inflammation of eyelid	0.706	0.294	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.706	0.294	0.000
J40 Bronchitis, not specified as acute or chronic	0.705	0.295	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.704	0.296	0.000
A80-A89 Viral infections of the central nervous system	0.703	0.297	0.000
L08 Other local infections of skin and subcutaneous tissue	0.703	0.297	0.000
C82.0 Small cleaved cell, follicular	0.703	0.297	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.700	0.300	0.000
J42 Unspecified chronic bronchitis	0.698	0.302	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.698	0.302	0.000
Q35-Q37 Cleft lip and cleft palate	0.698	0.302	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.698	0.302	0.000
B25-B34 Other viral diseases	0.698	0.302	0.000
S62.6 Fracture of other finger	0.697	0.303	0.000
U80.0 Penicillin resistant agent	0.697	0.303	0.000
C44.8 Overlapping lesion of skin	0.000	0.303	0.697
Q80-Q89 Other congenital malformations	0.696	0.304	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.695	0.305	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.695	0.305	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.695	0.305	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.695	0.305	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.695	0.305	0.000
T36 Poisoning by systemic antibiotics	0.695	0.305	0.000
Q51 Congenital malformations of uterus and cervix	0.695	0.305	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.695	0.305	0.000
T98 Sequelae of other and unspecified effects of external causes	0.695	0.305	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.693	0.307	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.691	0.309	0.000
S91 Open wound of ankle and foot	0.691	0.309	0.000
L50-L54 Urticaria and erythema	0.691	0.309	0.000
B18 Chronic viral hepatitis	0.691	0.309	0.000
I30 Acute pericarditis	0.690	0.310	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.690	0.310	0.000
I42.6 Alcoholic cardiomyopathy	0.689	0.311	0.000
C67.8 Overlapping lesion of bladder	0.689	0.311	0.000
C67.7 Urachus	0.689	0.311	0.000
I37 Pulmonary valve disorders	0.688	0.312	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.688	0.312	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.688	0.312	0.000
B07 Viral warts	0.687	0.313	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.686	0.314	0.000
H57 Other disorders of eye and adnexa	0.686	0.314	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.684	0.316	0.000
I51.4 Myocarditis, unspecified	0.684	0.316	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.683	0.317	0.000
C88 Malignant immunoproliferative diseases	0.683	0.317	0.000
I47.0 Reentry ventricular arrhythmia	0.682	0.318	0.000
C44.0 Skin of lip	0.000	0.318	0.682
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.682	0.318	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.320	0.680
C44.2 Skin of ear and external auricular canal	0.000	0.321	0.679
C18.1 Appendix	0.679	0.321	0.000
I36 Nonrheumatic tricuspid valve disorders	0.676	0.323	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.676	0.324	0.000
C77.8 Lymph nodes of multiple regions	0.675	0.324	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.675	0.325	0.000
C66 Malignant neoplasm of ureter	0.675	0.325	0.000
S90 Superficial injury of ankle and foot	0.673	0.327	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.672	0.328	0.000
H31 Other disorders of choroid	0.672	0.328	0.000
H30 Chorioretinal inflammation	0.672	0.328	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.672	0.328	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.672	0.328	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.672	0.328	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.671	0.328	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.671	0.329	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.671	0.329	0.000
I49.5 Sick sinus syndrome	0.670	0.330	0.000
C81 Hodgkin's disease	0.669	0.331	0.000
H20.9 Iridocyclitis, unspecified	0.669	0.331	0.000
C18.5 Splenic flexure	0.668	0.331	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.668	0.332	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.668	0.332	0.000
C13 Malignant neoplasm of hypopharynx	0.668	0.332	0.000
C11 Malignant neoplasm of nasopharynx	0.668	0.332	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.668	0.332	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.668	0.332	0.000
C05 Malignant neoplasm of palate	0.668	0.332	0.000
C04 Malignant neoplasm of floor of mouth	0.668	0.332	0.000
C03 Malignant neoplasm of gum	0.668	0.332	0.000
C00 Malignant neoplasm of lip	0.668	0.332	0.000
C12 Malignant neoplasm of pyriform sinus	0.668	0.332	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.668	0.332	0.000
C95 Leukaemia of unspecified cell type	0.668	0.332	0.000
C94 Other leukaemias of specified cell type	0.668	0.332	0.000
C93 Monocytic leukaemia	0.668	0.332	0.000
C86 Other specified types of T/NK-cell lymphoma	0.668	0.332	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.667	0.333	0.000
S42 Fracture of shoulder and upper arm	0.667	0.333	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.667	0.333	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.666	0.334	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.666	0.334	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.666	0.334	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.665	0.335	0.000
C21 Malignant neoplasm of anus and anal canal	0.665	0.335	0.000
Q76 Congenital malformations of spine and bony thorax	0.664	0.336	0.000
Q53 Undescended testicle	0.664	0.336	0.000
H04.9 Disorder of lachrymal system, unspecified	0.662	0.338	0.000
H04.6 Other changes in lachrymal passages	0.662	0.338	0.000
H04.4 Chronic inflammation of lachrymal passages	0.662	0.338	0.000
H04.0 Dacryoadenitis	0.662	0.338	0.000
S37 Injury of urinary and pelvic organs	0.662	0.338	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.661	0.339	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.661	0.339	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.660	0.340	0.000
T46.1 Calcium-channel blockers	0.660	0.340	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.660	0.340	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.340	0.660
T95 Sequelae of burns, corrosions and frostbite	0.659	0.341	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.659	0.341	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.659	0.341	0.000
C79 Secondary malignant neoplasm of other sites	0.659	0.341	0.000
S00-S09 Injuries to the head	0.659	0.341	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.656	0.344	0.000
S99 Other and unspecified injuries of ankle and foot	0.655	0.345	0.000
I51.0 Cardiac septal defect, acquired	0.654	0.346	0.000
C43.5 Malignant melanoma of trunk	0.005	0.346	0.649
Q65 Congenital deformities of hip	0.653	0.347	0.000
I05-I09 Chronic rheumatic heart diseases	0.653	0.347	0.000
C83.1 Small cleaved cell (diffuse)	0.652	0.348	0.000
S60 Superficial injury of wrist and hand	0.652	0.348	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.651	0.349	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.651	0.349	0.000
C07 Malignant neoplasm of parotid gland	0.650	0.349	0.000
H33 Retinal detachments and breaks	0.650	0.350	0.000
H34.9 Retinal vascular occlusion, unspecified	0.650	0.350	0.000
H34.0 Transient retinal artery occlusion	0.650	0.350	0.000
H05 Disorders of orbit	0.649	0.351	0.000
I20-I25 Ischaemic heart diseases	0.649	0.351	0.000
I46.1 Sudden cardiac death, so described	0.648	0.352	0.000
S62.60 Fracture of other finger (closed)	0.648	0.352	0.000
C17 Malignant neoplasm of small intestine	0.647	0.353	0.000
T91 Sequelae of injuries of neck and trunk	0.647	0.353	0.000
Q61 Cystic kidney disease	0.647	0.353	0.000
I49.2 Junctional premature depolarisation	0.646	0.353	0.000
H53-H54 Visual disturbances and blindness	0.645	0.354	0.000
I44.6 Other and unspecified fascicular block	0.644	0.356	0.000
H42 Glaucoma in diseases classified elsewhere	0.644	0.356	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.643	0.357	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.643	0.357	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.643	0.357	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.643	0.357	0.000
H17 Corneal scars and opacities	0.643	0.357	0.000
H15 Disorders of sclera	0.643	0.357	0.000
I45 Other conduction disorders	0.642	0.358	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.642	0.358	0.000
I35.8 Other aortic valve disorders	0.642	0.358	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.641	0.359	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.640	0.359	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.640	0.359	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.640	0.359	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.640	0.359	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.640	0.359	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.640	0.359	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.640	0.359	0.000
T40.4 Other synthetic narcotics	0.640	0.359	0.000
H18.4 Corneal degeneration	0.640	0.360	0.000
B16 Acute hepatitis B	0.638	0.362	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.637	0.362	0.000
H16 Keratitis	0.637	0.363	0.000
Q43 Other congenital malformations of intestine	0.637	0.363	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.636	0.364	0.000
I33 Acute and subacute endocarditis	0.635	0.365	0.000
H20.0 Acute and subacute iridocyclitis	0.634	0.366	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.633	0.367	0.000
T79-T79 Certain early complications of trauma	0.632	0.368	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.630	0.370	0.000
S93.0 Dislocation of ankle joint	0.629	0.371	0.000
I46.9 Cardiac arrest, unspecified	0.629	0.371	0.000
C80 Malignant neoplasm without specification of site	0.629	0.371	0.000
I60-I69 Cerebrovascular diseases	0.628	0.372	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.628	0.372	0.000
S36 Injury of intra-abdominal organs	0.628	0.372	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.628	0.372	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.628	0.372	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.628	0.372	0.000
S31 Open wound of abdomen, lower back and pelvis	0.628	0.372	0.000
S98 Traumatic amputation of ankle and foot	0.628	0.372	0.000
S97 Crushing injury of ankle and foot	0.628	0.372	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.628	0.372	0.000
S95 Injury of blood vessels at ankle and foot level	0.628	0.372	0.000
S94 Injury of nerves at ankle and foot level	0.628	0.372	0.000
C23 Malignant neoplasm of gallbladder	0.628	0.372	0.000
I35.9 Aortic valve disorder, unspecified	0.627	0.372	0.000
I51.5 Myocardial degeneration	0.627	0.373	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.627	0.373	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.627	0.373	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.627	0.373	0.000
Q78 Other osteochondrodysplasias	0.627	0.373	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.627	0.373	0.000
Q75 Other congenital malformations of skull and face bones	0.627	0.373	0.000
Q74 Other congenital malformations of limb(s)	0.627	0.373	0.000
Q73 Reduction defects of unspecified limb	0.627	0.373	0.000
Q72 Reduction defects of lower limb	0.627	0.373	0.000
Q71 Reduction defects of upper limb	0.627	0.373	0.000
Q70 Syndactyly	0.627	0.373	0.000
Q69 Polydactyly	0.627	0.373	0.000
Q68 Other congenital musculoskeletal deformities	0.627	0.373	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.627	0.373	0.000
S30.0 Contusion of lower back and pelvis	0.627	0.373	0.000
L10-L14 Bullous disorders	0.626	0.374	0.000
T17 Foreign body in respiratory tract	0.626	0.374	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.624	0.376	0.000
U50 Level of care administered to neonates	0.624	0.376	0.000
U07 Emergency use of U07	0.624	0.376	0.000
U06 Emergency use of U06	0.624	0.376	0.000
U04 Severe acute respiratory syndrome [SARS]	0.624	0.376	0.000
U52 First in a series of a regular day/night admissions	0.624	0.376	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.622	0.378	0.000
L04 Acute lymphadenitis	0.621	0.378	0.000
L01 Impetigo	0.621	0.378	0.000
L00 Staphylococcal scalded skin syndrome	0.621	0.378	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.621	0.379	0.000
T93.1 Sequelae of fracture of femur	0.620	0.380	0.000
T18 Foreign body in alimentary tract	0.620	0.380	0.000
H21 Other disorders of iris and ciliary body	0.618	0.382	0.000
T78 Adverse effects, not elsewhere classified	0.618	0.382	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.618	0.382	0.000
J60-J70 Lung diseases due to external agents	0.617	0.383	0.000
S93.1 Dislocation of toe(s)	0.615	0.385	0.000
C56 Malignant neoplasm of ovary	0.615	0.385	0.000
C82.6 Cutaneous follicle centre lymphoma	0.613	0.386	0.000
C82.5 Diffuse follicle centre lymphoma	0.613	0.386	0.000
C82.4 Follicular lymphoma grade IIIb	0.613	0.386	0.000
C82.3 Follicular lymphoma grade IIIa	0.613	0.386	0.000
C82.2 Large cell, follicular	0.613	0.386	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.613	0.386	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.611	0.389	0.000
I49.9 Cardiac arrhythmia, unspecified	0.611	0.389	0.000
S41 Open wound of shoulder and upper arm	0.610	0.390	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.609	0.391	0.000
T40.8 Lysergide [LSD]	0.609	0.391	0.000
T40.7 Cannabis (derivatives)	0.609	0.391	0.000
T40.6 Other and unspecified narcotics	0.609	0.391	0.000
T40.5 Cocaine	0.609	0.391	0.000
T40.3 Methadone	0.609	0.391	0.000
T40.1 Heroin	0.609	0.391	0.000
T40.0 Opium	0.609	0.391	0.000
S64 Injury of nerves at wrist and hand level	0.609	0.391	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.608	0.392	0.000
I42.5 Other restrictive cardiomyopathy	0.608	0.392	0.000
I42.4 Endocardial fibroelastosis	0.608	0.392	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.608	0.392	0.000
H36.0 Diabetic retinopathy	0.607	0.393	0.000
S30.2 Contusion of external genital organs	0.605	0.395	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.604	0.396	0.000
I42.2 Other hypertrophic cardiomyopathy	0.604	0.396	0.000
U89 Agent resistant to other and unspecified antibiotics	0.603	0.396	0.000
B83 Other helminthiases	0.603	0.397	0.000
B82 Unspecified intestinal parasitism	0.603	0.397	0.000
B81 Other intestinal helminthiases, not elsewhere classified	0.603	0.397	0.000
B78 Strongyloidiasis	0.603	0.397	0.000
B77 Ascariasis	0.603	0.397	0.000
B76 Hookworm diseases	0.603	0.397	0.000
B74 Filariasis	0.603	0.397	0.000
B71 Other cestode infections	0.603	0.397	0.000
B70 Diphyllobothriasis and sparganosis	0.603	0.397	0.000
B69 Cysticercosis	0.603	0.397	0.000
B68 Taeniasis	0.603	0.397	0.000
B67 Echinococcosis	0.603	0.397	0.000
B66 Other fluke infections	0.603	0.397	0.000
B65 Schistosomiasis [bilharziasis]	0.603	0.397	0.000
B79 Trichuriasis	0.603	0.397	0.000
B75 Trichinellosis	0.603	0.397	0.000
B73 Onchocerciasis	0.603	0.397	0.000
B72 Dracunculiasis	0.603	0.397	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.603	0.397	0.000
S70.1 Contusion of thigh	0.601	0.399	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.600	0.400	0.000
C18.8 Overlapping lesion of colon	0.599	0.400	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.599	0.401	0.000
I49.1 Atrial premature depolarisation	0.599	0.401	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.599	0.401	0.000
C10.9 Oropharynx, unspecified	0.599	0.401	0.000
T43.2 Other and unspecified antidepressants	0.598	0.402	0.000
Chapter XX External causes of morbidity and mortality	0.598	0.402	0.000
B19 Unspecified viral hepatitis	0.598	0.402	0.000
B17 Other acute viral hepatitis	0.598	0.402	0.000
B15 Acute hepatitis A	0.598	0.402	0.000
C25.0 Head of pancreas	0.597	0.403	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.597	0.403	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.597	0.403	0.000
T46.7 Peripheral vasodilators	0.597	0.403	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.597	0.403	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.597	0.403	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.597	0.403	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.597	0.403	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.007	0.403	0.590
S42.0 Fracture of clavicle	0.596	0.403	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.596	0.404	0.000
H40.8 Other glaucoma	0.596	0.404	0.000
H40.6 Glaucoma secondary to drugs	0.596	0.404	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations