TreeWAS – Variant ID: rs11258317

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.045	0.955	0.000
M06.9 Rheumatoid arthritis, unspecified	0.041	0.959	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.040	0.960	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.037	0.963	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.035	0.965	0.000
Z96.1 Presence of intraocular lens	0.000	0.969	0.031
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.031	0.969	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.031	0.969	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.030	0.970	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.029	0.971	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.027	0.973	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.023	0.977	0.000
N20.1 Calculus of ureter	0.015	0.985	0.000
M06 Other rheumatoid arthritis	0.014	0.986	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.988	0.012
S83.2 Tear of meniscus, current	0.000	0.988	0.012
M06.4 Inflammatory polyarthropathy	0.011	0.989	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.989	0.011
M06.8 Other specified rheumatoid arthritis	0.011	0.989	0.000
M06.2 Rheumatoid bursitis	0.010	0.989	0.000
M06.1 Adult-onset Still's disease	0.010	0.989	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.010	0.990	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.990	0.010
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.010	0.990	0.000
M06.3 Rheumatoid nodule	0.010	0.990	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
S91.0 Open wound of ankle	0.000	0.991	0.009
S91 Open wound of ankle and foot	0.000	0.991	0.009
M06.46 Inflammatory polyarthropathy (Lower leg)	0.009	0.991	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.991	0.009
N48 Other disorders of penis	0.000	0.991	0.009
M06.48 Inflammatory polyarthropathy (Other)	0.008	0.991	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.008	0.991	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.008	0.991	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.008	0.991	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.008	0.991	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.008	0.991	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.008	0.991	0.000
S91.3 Open wound of other parts of foot	0.000	0.992	0.008
N48.5 Ulcer of penis	0.000	0.992	0.008
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.008	0.992	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.992	0.008
M06.88 Other specified rheumatoid arthritis (Other)	0.008	0.992	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.008	0.992	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.008	0.992	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.008	0.992	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.008	0.992	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.008	0.992	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.008	0.992	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.008	0.992	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.008	0.992	0.000
N48.4 Impotence of organic origin	0.000	0.992	0.008
E21.3 Hyperparathyroidism, unspecified	0.008	0.992	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.008	0.992	0.000
M06.18 Adult-onset Still's disease (Other)	0.008	0.992	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.008	0.992	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.008	0.992	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.008	0.992	0.000
M06.14 Adult-onset Still's disease (Hand)	0.008	0.992	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.008	0.992	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.008	0.992	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.008	0.992	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.008	0.992	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.008	0.992	0.000
M06.28 Rheumatoid bursitis (Other)	0.008	0.992	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.008	0.992	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.008	0.992	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.008	0.992	0.000
M06.24 Rheumatoid bursitis (Hand)	0.008	0.992	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.008	0.992	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.008	0.992	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.008	0.992	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.008	0.992	0.000
M06.33 Rheumatoid nodule (Forearm)	0.008	0.992	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.992	0.008
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.008	0.992	0.000
S83.1 Dislocation of knee	0.000	0.992	0.008
S83.3 Tear of articular cartilage of knee, current	0.000	0.992	0.007
S83.0 Dislocation of patella	0.000	0.992	0.007
S83.7 Injury to multiple structures of knee	0.000	0.993	0.007
M06.37 Rheumatoid nodule (Ankle and foot)	0.007	0.993	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.007	0.993	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.007	0.993	0.000
M06.38 Rheumatoid nodule (Other)	0.007	0.993	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.007	0.993	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.007	0.993	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.007	0.993	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.993	0.007
M06.30 Rheumatoid nodule (Multiple sites)	0.007	0.993	0.000
M06.0 Seronegative rheumatoid arthritis	0.007	0.993	0.000
N48.1 Balanoposthitis	0.000	0.993	0.007
S81.0 Open wound of knee	0.000	0.993	0.007
N48.2 Other inflammatory disorders of penis	0.000	0.993	0.007
N20 Calculus of kidney and ureter	0.007	0.993	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.006	0.993	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.993	0.006
M06.34 Rheumatoid nodule (Hand)	0.006	0.994	0.000
G63.2 Diabetic polyneuropathy	0.006	0.994	0.000
N48.0 Leukoplakia of penis	0.000	0.994	0.006
N20.0 Calculus of kidney	0.006	0.994	0.000
C50.4 Upper-outer quadrant of breast	0.006	0.994	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.006	0.994	0.000
N48.3 Priapism	0.000	0.994	0.006
D48.1 Connective and other soft tissue	0.006	0.994	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.005	0.995	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.005	0.995	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.005	0.995	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.005	0.995	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.005	0.995	0.000
N48.9 Disorder of penis, unspecified	0.000	0.995	0.005
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.005	0.995	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.005	0.995	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
M87.9 Osteonecrosis, unspecified	0.005	0.995	0.000
M25.46 Effusion of joint (Lower leg)	0.005	0.995	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.004	0.995	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.004	0.996	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.004	0.996	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.004	0.996	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.004	0.996	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.004	0.996	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.004	0.996	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.004	0.996	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.004	0.996	0.000
N20.2 Calculus of kidney with calculus of ureter	0.004	0.996	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.004	0.996	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.004	0.996	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.004	0.996	0.000
N20.9 Urinary calculus, unspecified	0.004	0.996	0.000
N48.8 Other specified disorders of penis	0.000	0.996	0.004
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.003	0.997	0.000
J22 Unspecified acute lower respiratory infection	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.997	0.003
M87.96 Osteonecrosis, unspecified (Lower leg)	0.003	0.997	0.000
R58 Haemorrhage, not elsewhere classified	0.003	0.997	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.997	0.003
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
Y84.8 Other medical procedures	0.003	0.997	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.997	0.003
G63.8 Polyneuropathy in other diseases classified elsewhere	0.003	0.997	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.003	0.997	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.003	0.997	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.003	0.997	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.003	0.997	0.000
G63.1 Polyneuropathy in neoplastic disease	0.003	0.997	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.003	0.997	0.000
C50.1 Central portion of breast	0.003	0.997	0.000
N94.6 Dysmenorrhoea, unspecified	0.003	0.997	0.000
C50.5 Lower-outer quadrant of breast	0.003	0.997	0.000
C50 Malignant neoplasm of breast	0.003	0.997	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.003	0.997	0.000
N20-N23 Urolithiasis	0.003	0.997	0.000
N26 Unspecified contracted kidney	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.002	0.997	0.000
Y83.9 Surgical procedure, unspecified	0.000	0.997	0.003
E10.4 With neurological complications	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.002	0.998	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.002	0.998	0.000
N23 Unspecified renal colic	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
R04.0 Epistaxis	0.002	0.998	0.000
C50.6 Axillary tail of breast	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
R71 Abnormality of red blood cells	0.002	0.998	0.000
S81 Open wound of lower leg	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.002	0.998	0.000
M87 Osteonecrosis	0.002	0.998	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.002	0.998	0.000
M40.2 Other and unspecified kyphosis	0.002	0.998	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.002	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
Z91.5 Personal history of self-harm	0.000	0.998	0.002
M40.22 Other and unspecified kyphosis (Cervical region)	0.002	0.998	0.000
C50.8 Overlapping lesion of breast	0.002	0.998	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.002	0.998	0.000
N05.9 Unspecified	0.000	0.998	0.002
C50.3 Lower-inner quadrant of breast	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.002	0.998	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.002	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.002	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.002	0.998	0.000
N64.1 Fat necrosis of breast	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
R41.3 Other amnesia	0.000	0.998	0.002
M25.59 Pain in joint (Site unspecified)	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
L29.0 Pruritus ani	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
M87.3 Other secondary osteonecrosis	0.002	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.002	0.998	0.000
Z31.2 In vitro fertilisation	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.002	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.002	0.998	0.000
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.002	0.998	0.000
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.002	0.998	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.002	0.998	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.002	0.998	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.002	0.998	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.002	0.998	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.002	0.998	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.002	0.998	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.002	0.998	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.002	0.998	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.002
S80-S89 Injuries to the knee and lower leg	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
G60.3 Idiopathic progressive neuropathy	0.002	0.998	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.002	0.998	0.000
G60.1 Refsum's disease	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
S86 Injury of muscle and tendon at lower leg level	0.000	0.998	0.002
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
M87.8 Other osteonecrosis	0.002	0.998	0.000
K80.4 Calculus of bile duct with cholecystitis	0.002	0.998	0.000
D22.0 Melanocytic naevi of lip	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.998	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.998	0.002
S95 Injury of blood vessels at ankle and foot level	0.000	0.998	0.002
S94 Injury of nerves at ankle and foot level	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.000	0.998	0.002
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.001	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.001	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.001	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.001	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.001	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.001	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.001	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.001	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.001	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
W06.0 Home	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
G64 Other disorders of peripheral nervous system	0.002	0.998	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.998	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.001	0.998	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.001	0.998	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.998	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.001	0.998	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.001	0.998	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.001	0.998	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.001	0.998	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.001	0.998	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.001	0.998	0.000
M87.38 Other secondary osteonecrosis (Other)	0.001	0.998	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.001	0.998	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.001	0.998	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.001	0.998	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.001	0.998	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.001	0.998	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.001	0.998	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.001	0.998	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.001	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.001	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.000	0.998	0.001
F43.0 Acute stress reaction	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.001
S88 Traumatic amputation of lower leg	0.000	0.998	0.001
S87 Crushing injury of lower leg	0.000	0.998	0.001
S85 Injury of blood vessels at lower leg level	0.000	0.998	0.001
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.000	0.998	0.001
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.998	0.001
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.998	0.001
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.002	0.998	0.000
I46 Cardiac arrest	0.002	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.001	0.998	0.000
S92.0 Fracture of calcaneus	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.998	0.002
C10.9 Oropharynx, unspecified	0.001	0.998	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.001	0.998	0.000
D34 Benign neoplasm of thyroid gland	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.001	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.001	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.001
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.001
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.001
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.001
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.001
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.001
S94.1 Injury of medial plantar nerve	0.000	0.998	0.001
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.001
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.001
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.001
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.001
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.001
S95.1 Injury of plantar artery of foot	0.000	0.998	0.001
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.001
D28.2 Uterine tubes and ligaments	0.000	0.998	0.001
N64.4 Mastodynia	0.001	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.001
N21 Calculus of lower urinary tract	0.001	0.998	0.000
S84 Injury of nerves at lower leg level	0.000	0.998	0.001
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.001
D23.1 Skin of eyelid, including canthus	0.000	0.999	0.001
K07.6 Temporomandibular joint disorders	0.000	0.999	0.001
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.999	0.001
S98.3 Traumatic amputation of other parts of foot	0.000	0.999	0.001
S98.2 Traumatic amputation of two or more toes	0.000	0.999	0.001
S98.0 Traumatic amputation of foot at ankle level	0.000	0.999	0.001
S99 Other and unspecified injuries of ankle and foot	0.000	0.999	0.001
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
E10.2 With renal complications	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.001	0.999	0.000
J92.9 Pleural plaque without asbestos	0.000	0.999	0.001
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.000	0.999	0.001
S98.1 Traumatic amputation of one toe	0.000	0.999	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.001	0.999	0.000
C50.2 Upper-inner quadrant of breast	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.999	0.001
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.999	0.001
S85.8 Injury of other blood vessels at lower leg level	0.000	0.999	0.001
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.999	0.001
S85.5 Injury of popliteal vein	0.000	0.999	0.001
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.999	0.001
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.999	0.001
S85.2 Injury of peroneal artery	0.000	0.999	0.001
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.999	0.001
S85.0 Injury of popliteal artery	0.000	0.999	0.001
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.999	0.001
S87.0 Crushing injury of knee	0.000	0.999	0.001
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.999	0.001
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.999	0.001
S88.0 Traumatic amputation at knee level	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.000	0.999	0.001
R91 Abnormal findings on diagnostic imaging of lung	0.001	0.999	0.000
M05-M14 Inflammatory polyarthropathies	0.001	0.999	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.999	0.001
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.001	0.999	0.000
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.001	0.999	0.000
E27.8 Other specified disorders of adrenal gland	0.001	0.999	0.000
I46.1 Sudden cardiac death, so described	0.001	0.999	0.000
N21.1 Calculus in urethra	0.001	0.999	0.000
R87.6 Abnormal cytological findings	0.000	0.999	0.001
R94.4 Abnormal results of kidney function studies	0.001	0.999	0.000
E34 Other endocrine disorders	0.001	0.999	0.000
M14 Arthropathies in other diseases classified elsewhere	0.001	0.999	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
M86.9 Osteomyelitis, unspecified	0.001	0.999	0.000
Z80.3 Family history of malignant neoplasm of breast	0.001	0.999	0.000
M05 Seropositive rheumatoid arthritis	0.001	0.999	0.000
S92 Fracture of foot, except ankle	0.000	0.999	0.001
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.999	0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
H74.0 Tympanosclerosis	0.000	0.999	0.001
I12.0 Hypertensive renal disease with renal failure	0.001	0.999	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.001	0.999	0.000
N60.8 Other benign mammary dysplasias	0.001	0.999	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
C50.0 Nipple and areola	0.001	0.999	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
N05 Unspecified nephritic syndrome	0.000	0.999	0.001
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.999	0.001
E34.0 Carcinoid syndrome	0.001	0.999	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.999	0.001
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.999	0.001
S84.8 Injury of other nerves at lower leg level	0.000	0.999	0.001
S84.7 Injury of multiple nerves at lower leg level	0.000	0.999	0.001
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.999	0.001
S84.0 Injury of tibial nerve at lower leg level	0.000	0.999	0.001
S93.4 Sprain and strain of ankle	0.000	0.999	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.999	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.999	0.001
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.999	0.001
S99.7 Multiple injuries of ankle and foot	0.000	0.999	0.001
M86.98 Osteomyelitis, unspecified (Other)	0.001	0.999	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.001	0.999	0.000
D28.1 Vagina	0.000	0.999	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.999	0.000
M05.2 Rheumatoid vasculitis	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.000	0.999	0.001
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
M05.8 Other seropositive rheumatoid arthritis	0.001	0.999	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.001	0.999	0.000
S90.0 Contusion of ankle	0.000	0.999	0.001
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.999	0.001
F00 Dementia in Alzheimer's disease	0.001	0.999	0.000
E20.9 Hypoparathyroidism, unspecified	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.001	0.999	0.000
E34.5 Androgen resistance syndrome	0.001	0.999	0.000
E34.4 Constitutional tall stature	0.001	0.999	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.999	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.999	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.999	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.999	0.001
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.999	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.999	0.001
M09 Juvenile arthritis in diseases classified elsewhere	0.001	0.999	0.000
N64 Other disorders of breast	0.001	0.999	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.999	0.000
M79.16 Myalgia (Lower leg)	0.000	0.999	0.001
F43.2 Adjustment disorders	0.000	0.999	0.001
H06.2 Dysthyroid exophthalmos	0.001	0.999	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.999	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.999	0.000
M05.0 Felty's syndrome	0.001	0.999	0.000
M14.4 Arthropathy in amyloidosis	0.001	0.999	0.000
M14.3 Lipoid dermatoarthritis	0.001	0.999	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.001	0.999	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.001	0.999	0.000
N05.8 Other	0.000	0.999	0.001
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.999	0.001
N21.8 Other lower urinary tract calculus	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.000	0.999	0.001
Z31.4 Procreative investigation and testing	0.000	0.999	0.001
M08 Juvenile arthritis	0.001	0.999	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations