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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112979434
log Bayes Factor = 9.23181
Chromosome 12   position 9,885,707  (GRCh37) Explore rs112979434 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
E10.5 With peripheral circulatory complications
0.000 0.013 0.987
E27 Other disorders of adrenal gland
0.000 0.033 0.967
E34 Other endocrine disorders
0.000 0.043 0.957
E06 Thyroiditis
0.000 0.060 0.940
E22 Hyperfunction of pituitary gland
0.000 0.061 0.939
E34.9 Endocrine disorder, unspecified
0.000 0.071 0.929
E10.1 With ketoacidosis
0.000 0.076 0.924
E10.9 Without complications
0.000 0.085 0.915
E06.3 Autoimmune thyroiditis
0.000 0.098 0.902
E10.4 With neurological complications
0.000 0.118 0.882
E07 Other disorders of thyroid
0.000 0.127 0.873
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.143 0.857
E27.1 Primary adrenocortical insufficiency
0.000 0.146 0.854
E27.9 Disorder of adrenal gland, unspecified
0.000 0.154 0.846
E10.0 With coma
0.000 0.174 0.826
E10.8 With unspecified complications
0.000 0.177 0.823
E20 Hypoparathyroidism
0.000 0.178 0.822
E22.1 Hyperprolactinaemia
0.000 0.188 0.812
E10.2 With renal complications
0.000 0.192 0.808
E13 Other specified diabetes mellitus
0.000 0.193 0.807
E25 Adrenogenital disorders
0.000 0.197 0.803
E07.8 Other specified disorders of thyroid
0.000 0.201 0.799
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.210 0.790
E24 Cushing's syndrome
0.000 0.230 0.770
E34.0 Carcinoid syndrome
0.000 0.237 0.763
E27.8 Other specified disorders of adrenal gland
0.000 0.245 0.755
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.255 0.744
E27.2 Addisonian crisis
0.000 0.260 0.740
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.265 0.734
E06.5 Other chronic thyroiditis
0.000 0.266 0.733
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E20.9 Hypoparathyroidism, unspecified
0.000 0.302 0.698
E27.5 Adrenomedullary hyperfunction
0.000 0.307 0.693
E27.0 Other adrenocortical overactivity
0.000 0.307 0.693
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.308 0.692
E13.9 Without complications
0.000 0.310 0.690
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.311 0.689
E06.1 Subacute thyroiditis
0.000 0.311 0.688
E34.5 Androgen resistance syndrome
0.000 0.314 0.686
E34.4 Constitutional tall stature
0.000 0.314 0.686
E34.3 Short stature, not elsewhere classified
0.000 0.314 0.686
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.314 0.686
E34.1 Other hypersecretion of intestinal hormones
0.000 0.314 0.686
E28 Ovarian dysfunction
0.000 0.322 0.678
E24.9 Cushing's syndrome, unspecified
0.000 0.323 0.677
E06.4 Drug-induced thyroiditis
0.000 0.326 0.674
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.326 0.674
E06.0 Acute thyroiditis
0.000 0.326 0.674
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.327 0.673
E22.8 Other hyperfunction of pituitary gland
0.000 0.327 0.673
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.335 0.665
E22.0 Acromegaly and pituitary gigantism
0.000 0.338 0.662
E03.8 Other specified hypothyroidism
0.000 0.353 0.647
E31 Polyglandular dysfunction
0.000 0.355 0.645
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.359 0.641
E07.1 Dyshormogenetic goitre
0.000 0.374 0.626
E07.0 Hypersecretion of calcitonin
0.000 0.374 0.626
E40-E46 Malnutrition
0.000 0.383 0.616
E23 Hypofunction and other disorders of pituitary gland
0.000 0.384 0.616
E20.8 Other hypoparathyroidism
0.000 0.410 0.590
E20.1 Pseudohypoparathyroidism
0.000 0.410 0.590
E20.0 Idiopathic hypoparathyroidism
0.000 0.410 0.590
E34.8 Other specified endocrine disorders
0.000 0.415 0.584
E29 Testicular dysfunction
0.000 0.420 0.580
E13.8 With unspecified complications
0.000 0.421 0.579
E13.7 With multiple complications
0.000 0.421 0.579
E13.6 With other specified complications
0.000 0.421 0.579
E13.5 With peripheral circulatory complications
0.000 0.421 0.579
E13.4 With neurological complications
0.000 0.421 0.579
E13.2 With renal complications
0.000 0.421 0.579
E13.1 With ketoacidosis
0.000 0.421 0.579
E13.0 With coma
0.000 0.421 0.579
E25.9 Adrenogenital disorder, unspecified
0.000 0.424 0.576
E25.8 Other adrenogenital disorders
0.000 0.424 0.576
E07.9 Disorder of thyroid, unspecified
0.000 0.429 0.571
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.443 0.556
E24.8 Other Cushing's syndrome
0.000 0.448 0.552
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.448 0.552
E24.3 Ectopic ACTH syndrome
0.000 0.448 0.552
E24.1 Nelson's syndrome
0.000 0.448 0.552
E23.2 Diabetes insipidus
0.000 0.453 0.547
E16 Other disorders of pancreatic internal secretion
0.000 0.455 0.545
E03.1 Congenital hypothyroidism without goitre
0.000 0.457 0.543
E26 Hyperaldosteronism
0.000 0.457 0.543
E06.9 Thyroiditis, unspecified
0.000 0.459 0.541
E13.3 With ophthalmic complications
0.000 0.461 0.539
E28.3 Primary ovarian failure
0.000 0.464 0.536
E14 Unspecified diabetes mellitus
0.000 0.472 0.528
E15 Nondiabetic hypoglycaemic coma
0.000 0.473 0.527
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E30.9 Disorder of puberty, unspecified
0.000 0.488 0.512
E30.8 Other disorders of puberty
0.000 0.488 0.512
E30.1 Precocious puberty
0.000 0.488 0.512
E30.0 Delayed puberty
0.000 0.488 0.512
E32.9 Disease of thymus, unspecified
0.000 0.488 0.512
E32.8 Other diseases of thymus
0.000 0.488 0.512
E32.1 Abscess of thymus
0.000 0.488 0.512
E32.0 Persistent hyperplasia of thymus
0.000 0.488 0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.488 0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.488 0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.488 0.512
E50-E64 Other nutritional deficiencies
0.000 0.494 0.506
E10.6 With other specified complications
0.001 0.510 0.489
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.513 0.487
E28.9 Ovarian dysfunction, unspecified
0.000 0.514 0.486
E28.8 Other ovarian dysfunction
0.000 0.514 0.486
E28.1 Androgen excess
0.000 0.514 0.486
E28.0 Oestrogen excess
0.000 0.514 0.486
E24.0 Pituitary-dependent Cushing's disease
0.000 0.517 0.483
E24.2 Drug-induced Cushing's syndrome
0.000 0.520 0.480
E14.6 With other specified complications
0.000 0.533 0.467
E31.9 Polyglandular dysfunction, unspecified
0.000 0.537 0.463
E31.8 Other polyglandular dysfunction
0.000 0.537 0.463
E31.1 Polyglandular hyperfunction
0.000 0.537 0.463
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.558 0.442
E45 Retarded development following protein-energy malnutrition
0.000 0.558 0.442
E43 Unspecified severe protein-energy malnutrition
0.000 0.558 0.442
E42 Marasmic kwashiorkor
0.000 0.558 0.442
E41 Nutritional marasmus
0.000 0.558 0.442
E40 Kwashiorkor
0.000 0.558 0.442
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.558 0.441
E23.1 Drug-induced hypopituitarism
0.000 0.558 0.441
E21.2 Other hyperparathyroidism
0.000 0.564 0.436
E14.2 Withrenal complications
0.000 0.564 0.436
E23.6 Other disorders of pituitary gland
0.000 0.576 0.424
E29.9 Testicular dysfunction, unspecified
0.000 0.584 0.416
E29.8 Other testicular dysfunction
0.000 0.584 0.416
E29.0 Testicular hyperfunction
0.000 0.584 0.416
E16.2 Hypoglycaemia, unspecified
0.000 0.587 0.413
E16.1 Other hypoglycaemia
0.000 0.588 0.411
E61 Deficiency of other nutrient elements
0.000 0.591 0.409
E21.4 Other specified disorders of parathyroid gland
0.000 0.592 0.407
E11 Non-insulin-dependent diabetes mellitus
0.000 0.593 0.407
E14.5 With peripheral circulatory complications
0.000 0.604 0.396
E31.0 Autoimmune polyglandular failure
0.000 0.606 0.394
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.609 0.391
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.609 0.391
E16.4 Abnormal secretion of gastrin
0.000 0.609 0.391
E16.3 Increased secretion of glucagon
0.000 0.609 0.391
E26.8 Other hyperaldosteronism
0.000 0.610 0.389
E26.1 Secondary hyperaldosteronism
0.000 0.610 0.389
E14.7 With multiple complications
0.000 0.621 0.379
E56 Other vitamin deficiencies
0.000 0.622 0.377
E65-E68 Obesity and other hyperalimentation
0.000 0.623 0.377
E28.2 Polycystic ovarian syndrome
0.000 0.632 0.368
E26.9 Hyperaldosteronism, unspecified
0.000 0.634 0.365
E14.1 With ketoacidosis
0.000 0.637 0.363
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.637 0.363
E50 Vitamin A deficiency
0.000 0.637 0.363
E60 Dietary zinc deficiency
0.000 0.637 0.363
E59 Dietary selenium deficiency
0.000 0.637 0.363
E52 Niacin deficiency [pellagra]
0.000 0.637 0.363
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.638 0.362
E14.0 With coma
0.000 0.642 0.358
E11.5 With peripheral circulatory complications
0.000 0.651 0.349
E14.8 With unspecified complications
0.000 0.652 0.348
E61.1 Iron deficiency
0.000 0.653 0.347
E51 Thiamine deficiency
0.000 0.654 0.346
E14.4 With neurological complications
0.000 0.658 0.342
E46 Unspecified protein-energy malnutrition
0.000 0.658 0.342
E11.2 With renal complications
0.000 0.659 0.341
E54 Ascorbic acid deficiency
0.000 0.660 0.340
E11.6 With other specified complications
0.000 0.660 0.340
E63 Other nutritional deficiencies
0.000 0.661 0.339
E58 Dietary calcium deficiency
0.000 0.662 0.338
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.664 0.336
E11.1 With ketoacidosis
0.000 0.676 0.324
E53 Deficiency of other B group vitamins
0.000 0.677 0.323
E21.3 Hyperparathyroidism, unspecified
0.000 0.679 0.321
E44.1 Mild protein-energy malnutrition
0.000 0.683 0.317
E44.0 Moderate protein-energy malnutrition
0.000 0.683 0.317
E23.7 Disorder of pituitary gland, unspecified
0.000 0.683 0.316
E61.9 Deficiency of nutrient element, unspecified
0.000 0.707 0.293
E61.8 Deficiency of other specified nutrient elements
0.000 0.707 0.293
E61.7 Deficiency of multiple nutrient elements
0.000 0.707 0.293
E61.6 Vanadium deficiency
0.000 0.707 0.293
E61.5 Molybdenum deficiency
0.000 0.707 0.293
E61.4 Chromium deficiency
0.000 0.707 0.293
E61.3 Manganese deficiency
0.000 0.707 0.293
E61.0 Copper deficiency
0.000 0.707 0.293
E11.7 With multiple complications
0.000 0.708 0.292
E56.1 Deficiency of vitamin K
0.000 0.714 0.285
E29.1 Testicular hypofunction
0.000 0.718 0.281
E61.2 Magnesium deficiency
0.000 0.721 0.279
E56.9 Vitamin deficiency, unspecified
0.000 0.729 0.271
E56.8 Deficiency of other vitamins
0.000 0.729 0.271
E56.0 Deficiency of vitamin E
0.000 0.729 0.271
E67 Other hyperalimentation
0.000 0.729 0.271
E68 Sequelae of hyperalimentation
0.000 0.729 0.271
E26.0 Primary hyperaldosteronism
0.001 0.738 0.262
E53.9 Vitamin B deficiency, unspecified
0.000 0.739 0.261
E50.9 Vitamin A deficiency, unspecified
0.000 0.740 0.260
E50.8 Other manifestations of vitamin A deficiency
0.000 0.740 0.260
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.740 0.260
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.740 0.260
E50.5 Vitamin A deficiency with night blindness
0.000 0.740 0.260
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.740 0.260
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.740 0.260
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.740 0.260
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.740 0.260
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.740 0.260
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.740 0.260
E64.8 Sequelae of other nutritional deficiencies
0.000 0.740 0.260
E64.3 Sequelae of rickets
0.000 0.740 0.260
E64.2 Sequelae of vitamin C deficiency
0.000 0.740 0.260
E64.1 Sequelae of vitamin A deficiency
0.000 0.740 0.260
E64.0 Sequelae of protein-energy malnutrition
0.000 0.740 0.260
E11.0 With coma
0.000 0.744 0.255
E55 Vitamin D deficiency
0.000 0.749 0.251
E23.0 Hypopituitarism
0.000 0.750 0.250
E51.9 Thiamine deficiency, unspecified
0.000 0.752 0.248
E51.8 Other manifestations of thiamine deficiency
0.000 0.752 0.248
E51.1 Beriberi
0.000 0.752 0.248
E63.8 Other specified nutritional deficiencies
0.000 0.757 0.243
E63.1 Imbalance of constituents of food intake
0.000 0.757 0.243
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.757 0.243
E53.1 Pyridoxine deficiency
0.000 0.768 0.231
E53.0 Riboflavin deficiency
0.000 0.768 0.231
E51.2 Wernicke's encephalopathy
0.000 0.769 0.231
E11.8 With unspecified complications
0.000 0.774 0.226
E63.9 Nutritional deficiency, unspecified
0.000 0.781 0.219
E14.3 With ophthalmic complications
0.000 0.789 0.211
E67.8 Other specified hyperalimentation
0.000 0.806 0.194
E67.3 Hypervitaminosis D
0.000 0.806 0.194
E67.2 Megavitamin-B6 syndrome
0.000 0.806 0.194
E67.1 Hypercarotenaemia
0.000 0.806 0.194
E67.0 Hypervitaminosis A
0.000 0.806 0.194
E11.4 With neurological complications
0.000 0.808 0.192
E55.0 Rickets, active
0.000 0.820 0.180
E65 Localised adiposity
0.000 0.826 0.174
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.841 0.159
E14.9 Without complications
0.000 0.843 0.157
E66 Obesity
0.000 0.857 0.143
E53.8 Deficiency of other specified B group vitamins
0.000 0.871 0.129
E66.0 Obesity due to excess calories
0.000 0.874 0.126
E05.5 Thyroid crisis or storm
0.000 0.886 0.114
E05.4 Thyrotoxicosis factitia
0.000 0.886 0.114
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.886 0.114
E04 Other non-toxic goitre
0.000 0.892 0.107
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.895 0.105
E66.1 Drug-induced obesity
0.000 0.897 0.103
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.907 0.093
E11.3 With ophthalmic complications
0.000 0.910 0.090
E21.0 Primary hyperparathyroidism
0.000 0.914 0.086
E05.8 Other thyrotoxicosis
0.000 0.916 0.084
E11.9 Without complications
0.000 0.919 0.081
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.920 0.080
E04.8 Other specified non-toxic goitre
0.000 0.922 0.077
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.923 0.077
E66.8 Other obesity
0.000 0.926 0.074
E04.0 Non-toxic diffuse goitre
0.000 0.932 0.068
E55.9 Vitamin D deficiency, unspecified
0.000 0.932 0.068
E04.2 Non-toxic multinodular goitre
0.000 0.941 0.059
E05.9 Thyrotoxicosis, unspecified
0.000 0.955 0.045
E04.9 Non-toxic goitre, unspecified
0.000 0.985 0.014
D12.6 Colon, unspecified
0.000 0.990 0.010
Z63.8 Other specified problems related to primary support group
0.010 0.990 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.000 0.991 0.009
K51.2 Ulcerative (chronic) proctitis
0.000 0.992 0.008
Z63 Other problems related to primary support group, including family circumstances
0.008 0.992 0.000
E04.1 Non-toxic single thyroid nodule
0.002 0.992 0.006
Z63.7 Other stressful life events affecting family and household
0.008 0.992 0.000
S32.0 Fracture of lumbar vertebra
0.000 0.992 0.007
M22.4 Chondromalacia patellae
0.000 0.993 0.007
Z63.6 Dependent relative needing care at home
0.007 0.993 0.000
S32 Fracture of lumbar spine and pelvis
0.000 0.993 0.007
M22.8 Other disorders of patella
0.000 0.993 0.007
S32.5 Fracture of pubis
0.000 0.994 0.006
S32.4 Fracture of acetabulum
0.000 0.994 0.006
S32.50 Fracture of pubis (closed)
0.000 0.994 0.006
S62.40 Multiple fractures of metacarpal bones (closed)
0.006 0.994 0.000
S65 Injury of blood vessels at wrist and hand level
0.006 0.994 0.000
S65.1 Injury of radial artery at wrist and hand level
0.006 0.994 0.000
S32.40 Fracture of acetabulum (closed)
0.000 0.994 0.006
R80 Isolated proteinuria
0.006 0.994 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.000 0.994 0.006
S62.4 Multiple fractures of metacarpal bones
0.006 0.994 0.000
Z63.9 Problem related to primary support group, unspecified
0.006 0.994 0.000
Z63.3 Absence of family member
0.006 0.994 0.000
Z63.2 Inadequate family support
0.006 0.994 0.000
Z63.1 Problems in relationship with parents and in-laws
0.006 0.994 0.000
S65.5 Injury of blood vessel(s) of other finger
0.006 0.994 0.000
Z63.5 Disruption of family by separation and divorce
0.006 0.994 0.000
S62 Fracture at wrist and hand level
0.006 0.994 0.000
S62.7 Multiple fractures of fingers
0.006 0.994 0.000
S32.1 Fracture of sacrum
0.000 0.994 0.006
Z63.4 Disappearance and death of family member
0.006 0.994 0.000
S62.20 Fracture of first metacarpal bone (closed)
0.006 0.994 0.000
S62.2 Fracture of first metacarpal bone
0.006 0.994 0.000
M22 Disorders of patella
0.000 0.994 0.006
S32.01 Fracture of lumbar vertebra (open)
0.000 0.994 0.005
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.006 0.994 0.000
N75.0 Cyst of Bartholin's gland
0.000 0.994 0.006
C21.1 Anal canal
0.006 0.994 0.000
E70-E90 Metabolic disorders
0.000 0.994 0.006
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.000 0.994 0.005
S62.71 Multiple fractures of fingers (open)
0.005 0.994 0.000
S00.8 Superficial injury of other parts of head
0.005 0.995 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.995 0.005
S60-S69 Injuries to the wrist and hand
0.005 0.995 0.000
Z63.0 Problems in relationship with spouse or partner
0.005 0.995 0.000
S65.4 Injury of blood vessel(s) of thumb
0.005 0.995 0.000
M22.9 Disorder of patella, unspecified
0.000 0.995 0.005
S64 Injury of nerves at wrist and hand level
0.005 0.995 0.000
S32.2 Fracture of coccyx
0.000 0.995 0.005
S63.0 Dislocation of wrist
0.005 0.995 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.005 0.995 0.000
S63.5 Sprain and strain of wrist
0.005 0.995 0.000
S32.10 Fracture of sacrum (closed)
0.000 0.995 0.005
S64.4 Injury of digital nerve of other finger
0.005 0.995 0.000
E85 Amyloidosis
0.000 0.995 0.005
S64.3 Injury of digital nerve of thumb
0.005 0.995 0.000
S32.51 Fracture of pubis (open)
0.000 0.995 0.005
S62.70 Multiple fractures of fingers (closed)
0.005 0.995 0.000
Z50.5 Speech therapy
0.005 0.995 0.000
S32.41 Fracture of acetabulum (open)
0.000 0.995 0.005
S65.9 Injury of unspecified blood vessel at wrist and hand level
0.005 0.995 0.000
S65.8 Injury of other blood vessels at wrist and hand level
0.005 0.995 0.000
S65.7 Injury of multiple blood vessels at wrist and hand level
0.005 0.995 0.000
S65.3 Injury of deep palmar arch
0.005 0.995 0.000
S65.2 Injury of superficial palmar arch
0.005 0.995 0.000
S91.1 Open wound of toe(s) without damage to nail
0.000 0.995 0.005
E66.9 Obesity, unspecified
0.000 0.995 0.005
S65.0 Injury of ulnar artery at wrist and hand level
0.005 0.995 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.005 0.995 0.000
C21 Malignant neoplasm of anus and anal canal
0.005 0.995 0.000
S62.5 Fracture of thumb
0.005 0.995 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.005 0.995 0.000
C21.0 Anus, unspecified
0.005 0.995 0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)
0.000 0.995 0.004
S62.41 Multiple fractures of metacarpal bones (open)
0.004 0.995 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.005 0.995 0.000
E84 Cystic fibrosis
0.000 0.995 0.004
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.995 0.004
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.000 0.995 0.004
S01.3 Open wound of ear
0.004 0.996 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.004 0.996 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.996 0.004
S32.3 Fracture of ilium
0.000 0.996 0.004
S60.8 Other superficial injuries of wrist and hand
0.004 0.996 0.000
S32.11 Fracture of sacrum (open)
0.000 0.996 0.004
S63.7 Sprain and strain of other and unspecified parts of hand
0.004 0.996 0.000
S63.2 Multiple dislocations of fingers
0.004 0.996 0.000
S62.21 Fracture of first metacarpal bone (open)
0.004 0.996 0.000
M22.1 Recurrent subluxation of patella
0.000 0.996 0.004
S64.7 Injury of multiple nerves at wrist and hand level
0.004 0.996 0.000
S60 Superficial injury of wrist and hand
0.004 0.996 0.000
K72.0 Acute and subacute hepatic failure
0.000 0.996 0.004
S63.1 Dislocation finger
0.004 0.996 0.000
E85.4 Organ-limited amyloidosis
0.000 0.996 0.004
E77 Disorders of glycoprotein metabolism
0.000 0.996 0.004
E76 Disorders of glycosaminoglycan metabolism
0.000 0.996 0.004
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.996 0.004
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.996 0.004
E85.3 Secondary systemic amyloidosis
0.000 0.996 0.004
E85.8 Other amyloidosis
0.000 0.996 0.004
S62.1 Fracture of other carpal bone(s)
0.004 0.996 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.996 0.004
S62.0 Fracture of navicular [scaphoid] bone of hand
0.004 0.996 0.000
S61.1 Open wound of finger(s) with damage to nail
0.004 0.996 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.996 0.004
S01.7 Multiple open wounds of head
0.000 0.996 0.004
S32.21 Fracture of coccyx (open)
0.000 0.996 0.004
S32.20 Fracture of coccyx (closed)
0.000 0.996 0.004
S64.9 Injury of unspecified nerve at wrist and hand level
0.004 0.996 0.000
S64.8 Injury of other nerves at wrist and hand level
0.004 0.996 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.996 0.004
S62.50 Fracture of thumb (closed)
0.004 0.996 0.000
S63.6 Sprain and strain of finger(s)
0.004 0.996 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.004 0.996 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.996 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.996 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.996 0.004
M22.3 Other derangements of patella
0.000 0.996 0.004
C45.0 Mesothelioma of pleura
0.000 0.996 0.004
E83.3 Disorders of phosphorus metabolism
0.000 0.996 0.004
E75.5 Other lipid storage disorders
0.000 0.996 0.004
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.004 0.996 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.996 0.004
M22.0 Recurrent dislocation of patella
0.000 0.996 0.004
S63.3 Traumatic rupture of ligament of wrist and carpus
0.004 0.996 0.000
C21.2 Cloacogenic zone
0.004 0.996 0.000
S62.3 Fracture of other metacarpal bone
0.004 0.996 0.000
S64.1 Injury of median nerve at wrist and hand level
0.004 0.996 0.000
C45 Mesothelioma
0.000 0.996 0.004
E70.3 Albinism
0.000 0.996 0.003
L73.2 Hidradenitis suppurativa
0.000 0.996 0.004
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.004 0.996 0.000
C45.9 Mesothelioma, unspecified
0.000 0.996 0.004
S05.1 Contusion of eyeball and orbital tissues
0.004 0.996 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.004 0.996 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.004 0.996 0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)
0.003 0.996 0.000
C45.7 Mesothelioma of other sites
0.000 0.996 0.003
E75.6 Lipid storage disorder, unspecified
0.000 0.996 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.996 0.003
E75.3 Sphingolipidosis, unspecified
0.000 0.996 0.003
E75.2 Other sphingolipidosis
0.000 0.996 0.003
E75.1 Other gangliosidosis
0.000 0.996 0.003
E75.0 GM2 gangliosidosis
0.000 0.996 0.003
S60.0 Contusion of finger(s) without damage to nail
0.003 0.996 0.000
R54 Senility
0.004 0.996 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.996 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.996 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.996 0.003
S60.7 Multiple superficial injuries of wrist and hand
0.003 0.996 0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)
0.000 0.996 0.003
K11.8 Other diseases of salivary glands
0.003 0.997 0.000
S61 Open wound of wrist and hand
0.003 0.997 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.997 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.997 0.003
E70.2 Disorders of tyrosine metabolism
0.000 0.997 0.003
E70.1 Other hyperphenylalaninaemias
0.000 0.997 0.003
E70.0 Classical phenylketonuria
0.000 0.997 0.003
S32.31 Fracture of ilium (open)
0.000 0.997 0.003
S62.51 Fracture of thumb (open)
0.003 0.997 0.000
E74.0 Glycogen storage disease
0.000 0.997 0.003
E85.9 Amyloidosis, unspecified
0.000 0.997 0.003
M22.10 Recurrent subluxation of patella, unspecified knee
0.000 0.997 0.003
S60.2 Contusion of other parts of wrist and hand
0.003 0.997 0.000
S05 Injury of eye and orbit
0.003 0.997 0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb
0.003 0.997 0.000
C50.3 Lower-inner quadrant of breast
0.000 0.997 0.003
E71.3 Disorders of fatty-acid metabolism
0.000 0.997 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.997 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.997 0.003
E71.0 Maple-syrup-urine disease
0.000 0.997 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.997 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.997 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.997 0.003
E76.2 Other mucopolysaccharidoses
0.000 0.997 0.003
E76.1 Mucopolysaccharidosis, type II
0.000 0.997 0.003
E76.0 Mucopolysaccharidosis, type I
0.000 0.997 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.997 0.003
E77.8 Other disorders of glycoprotein metabolism
0.000 0.997 0.003
E77.1 Defects in glycoprotein degradation
0.000 0.997 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.997 0.003
K60.3 Anal fistula
0.003 0.997 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.997 0.003
E73 Lactose intolerance
0.000 0.997 0.003
S62.11 Fracture of other carpal bone(s) (open)
0.003 0.997 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.997 0.003
E74.2 Disorders of galactose metabolism
0.000 0.997 0.003
E74.1 Disorders of fructose metabolism
0.000 0.997 0.003
S91 Open wound of ankle and foot
0.000 0.997 0.003
S62.01 Fracture of navicular [scaphoid] bone of hand (open)
0.003 0.997 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.997 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.997 0.003
E72.5 Disorders of glycine metabolism
0.000 0.997 0.003
E72.4 Disorders of ornithine metabolism
0.000 0.997 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.997 0.003
E72.2 Disorders of urea cycle metabolism
0.000 0.997 0.003
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.003 0.997 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.003 0.997 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.003 0.997 0.000
S67 Crushing injury of wrist and hand
0.003 0.997 0.000
S05.9 Injury of eye and orbit, part unspecified
0.003 0.997 0.000
E72.0 Disorders of amino-acid transport
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.997 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
E79.1 Lesch-Nyhan syndrome
0.000 0.997 0.003
S64.2 Injury of radial nerve at wrist and hand level
0.003 0.997 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.003 0.997 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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