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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113224532
log Bayes Factor = 21.9139
Chromosome 4   position 120,311,412  (GRCh37) Explore rs113224532 on Ensembl!
Variant rs113224532 is part of Cluster X0033

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
H25-H28 Disorders of lens
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
C18 Malignant neoplasm of colon
1.000 0.000 0.000
Z87 Personal history of other diseases and conditions
1.000 0.000 0.000
Z87.1 Personal history of diseases of the digestive system
0.999 0.001 0.000
H25 Senile cataract
0.999 0.001 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.998 0.002 0.000
C79 Secondary malignant neoplasm of other sites
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
Z98 Other postsurgical states
0.993 0.007 0.000
Z98.0 Intestinal bypass and anastomosis status
0.992 0.008 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.987 0.013 0.000
H25.8 Other senile cataract
0.980 0.020 0.000
Z51.1 Chemotherapy session for neoplasm
0.978 0.022 0.000
C34 Malignant neoplasm of bronchus and lung
0.978 0.022 0.000
C18.9 Colon, unspecified
0.976 0.024 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.976 0.024 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.975 0.025 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.971 0.029 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.958 0.042 0.000
H40-H42 Glaucoma
0.956 0.044 0.000
B25-B34 Other viral diseases
0.955 0.045 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.952 0.048 0.000
H26 Other cataract
0.947 0.053 0.000
Z90.3 Acquired absence of part of stomach
0.947 0.053 0.000
H25.1 Senile nuclear cataract
0.946 0.054 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.945 0.055 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.943 0.057 0.000
Z43 Attention to artificial openings
0.939 0.061 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.937 0.063 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.937 0.063 0.000
C34.9 Bronchus or lung, unspecified
0.933 0.067 0.000
H26.4 After-cataract
0.933 0.067 0.000
C18.0 Caecum
0.932 0.068 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.931 0.069 0.000
H25.0 Senile incipient cataract
0.929 0.071 0.000
C77.1 Intrathoracic lymph nodes
0.929 0.071 0.000
H40 Glaucoma
0.925 0.075 0.000
Z90.2 Acquired absence of lung [part of]
0.924 0.076 0.000
Z90.1 Acquired absence of breast(s)
0.923 0.077 0.000
B34 Viral infection of unspecified site
0.923 0.077 0.000
C34.1 Upper lobe, bronchus or lung
0.921 0.079 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.920 0.080 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.920 0.080 0.000
C50-C50 Malignant neoplasm of breast
0.919 0.081 0.000
Z51.5 Palliative care
0.915 0.085 0.000
Z94 Transplanted organ and tissue status
0.913 0.087 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.912 0.088 0.000
B35-B49 Mycoses
0.909 0.091 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.906 0.094 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.902 0.098 0.000
Chapter VIII Diseases of the ear and mastoid process
0.900 0.100 0.000
B34.9 Viral infection, unspecified
0.900 0.100 0.000
Z45 Adjustment and management of implanted device
0.892 0.108 0.000
C18.7 Sigmoid colon
0.890 0.110 0.000
Z83 Family history of other specific disorders
0.885 0.115 0.000
Z51.3 Blood transfusion without reported diagnosis
0.883 0.117 0.000
Z43.2 Attention to ileostomy
0.882 0.118 0.000
Z51.2 Other chemotherapy
0.880 0.120 0.000
H25.9 Senile cataract, unspecified
0.879 0.121 0.000
Chapter V Mental and behavioural disorders
0.877 0.123 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.877 0.123 0.000
Z46 Fitting and adjustment of other devices
0.874 0.126 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.869 0.130 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.864 0.136 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.864 0.136 0.000
C50 Malignant neoplasm of breast
0.862 0.138 0.000
T40.2 Other opioids
0.861 0.139 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.860 0.140 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.860 0.140 0.000
C18.2 Ascending colon
0.858 0.142 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.856 0.144 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.856 0.144 0.000
Z45.2 Adjustment and management of vascular access device
0.855 0.145 0.000
C16 Malignant neoplasm of stomach
0.855 0.145 0.000
H40.1 Primary open-angle glaucoma
0.855 0.145 0.000
H43-H45 Disorders of vitreous body and globe
0.854 0.146 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.852 0.148 0.000
Z51.8 Other specified medical care
0.851 0.149 0.000
T92 Sequelae of injuries of upper limb
0.845 0.155 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.845 0.155 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.845 0.155 0.000
C18.6 Descending colon
0.844 0.156 0.000
S60-S69 Injuries to the wrist and hand
0.840 0.160 0.000
C15 Malignant neoplasm of oesophagus
0.839 0.161 0.000
C34.0 Main bronchus
0.836 0.164 0.000
C77.9 Lymph node, unspecified
0.834 0.166 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.833 0.167 0.000
H40.0 Glaucoma suspect
0.832 0.168 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.831 0.169 0.000
T39.1 4-Aminophenol derivatives
0.831 0.169 0.000
Y52 Agents primarily affecting the cardiovascular system
0.829 0.171 0.000
Z29 Need for other prophylactic measures
0.827 0.173 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.824 0.176 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.822 0.178 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.820 0.180 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.818 0.182 0.000
Z94.7 Corneal transplant status
0.817 0.182 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.817 0.183 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.817 0.183 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.815 0.185 0.000
Z83.3 Family history of diabetes mellitus
0.811 0.188 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.811 0.189 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.809 0.191 0.000
S10-S19 Injuries to the neck
0.804 0.196 0.000
H40.9 Glaucoma, unspecified
0.803 0.197 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.802 0.198 0.000
Z90.8 Acquired absence of other organs
0.802 0.198 0.000
C18.1 Appendix
0.800 0.200 0.000
B35 Dermatophytosis
0.799 0.201 0.000
C25 Malignant neoplasm of pancreas
0.799 0.201 0.000
C77.0 Lymph nodes of head, face and neck
0.798 0.202 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.797 0.203 0.000
S70-S79 Injuries to the hip and thigh
0.796 0.204 0.000
C43 Malignant melanoma of skin
0.796 0.204 0.000
C18.5 Splenic flexure
0.796 0.204 0.000
Z43.5 Attention to cyctostomy
0.795 0.205 0.000
V80-V89 Other land transport accidents
0.793 0.207 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.792 0.208 0.000
A30-A49 Other bacterial diseases
0.791 0.209 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.791 0.209 0.000
B15-B19 Viral hepatitis
0.790 0.210 0.000
H90-H95 Other disorders of ear
0.789 0.211 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.788 0.212 0.000
H65-H75 Diseases of middle ear and mastoid
0.787 0.213 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.782 0.218 0.000
T90 Sequelae of injuries of head
0.782 0.218 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.781 0.219 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.781 0.219 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.781 0.219 0.000
Z04 Examination and observation for other reasons
0.779 0.221 0.000
T42.4 Benzodiazepines
0.777 0.223 0.000
V20-V29 Motorcycle rider injured in transport accident
0.777 0.223 0.000
T91 Sequelae of injuries of neck and trunk
0.776 0.224 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.776 0.224 0.000
A15-A19 Tuberculosis
0.776 0.224 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.775 0.225 0.000
Y43 Primarily systemic agents
0.775 0.225 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.774 0.226 0.000
Z53.9 Procedure not carried out, unspecified reason
0.774 0.226 0.000
B99-B99 Other infectious diseases
0.773 0.227 0.000
B37 Candidiasis
0.772 0.228 0.000
Z87.0 Personal history of diseases of the respiratory system
0.771 0.229 0.000
C18.4 Transverse colon
0.766 0.234 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.765 0.235 0.000
Chapter VI Diseases of the nervous system
0.764 0.236 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.762 0.238 0.000
Z83.5 Family history of eye and ear disorders
0.761 0.239 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.760 0.240 0.000
H27 Other disorders of lens
0.760 0.240 0.000
Z22 Carrier of infectious disease
0.759 0.241 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.759 0.241 0.000
H18 Other disorders of cornea
0.759 0.241 0.000
C50.0 Nipple and areola
0.758 0.242 0.000
C77.3 Axillary and upper limb lymph nodes
0.758 0.242 0.000
C79.6 Secondary malignant neoplasm of ovary
0.757 0.242 0.000
A80-A89 Viral infections of the central nervous system
0.756 0.244 0.000
T40.4 Other synthetic narcotics
0.756 0.244 0.000
F60-F69 Disorders of adult personality and behaviour
0.754 0.246 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.753 0.247 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.752 0.248 0.000
Z94.4 Liver transplant status
0.751 0.249 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.751 0.249 0.000
C79.2 Secondary malignant neoplasm of skin
0.750 0.250 0.000
Z80 Family history of malignant neoplasm
0.749 0.251 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.749 0.251 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.748 0.252 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.748 0.252 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.746 0.254 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.746 0.254 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.745 0.255 0.000
Z81 Family history of mental and behavioural disorders
0.744 0.256 0.000
W20-W49 Exposure to inanimate mechanical forces
0.743 0.257 0.000
T86 Failure and rejection of transplanted organs and tissues
0.743 0.257 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.742 0.258 0.000
Y48 Anaesthetics and therapeutic gases
0.741 0.259 0.000
B95-B98 Bacterial, viral and other infectious agents
0.741 0.259 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
H26.8 Other specified cataract
0.739 0.261 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.738 0.262 0.000
C50.4 Upper-outer quadrant of breast
0.738 0.262 0.000
Z29.2 Other prophylactic chemotherapy
0.738 0.262 0.000
Chapter XXII Codes for special purposes
0.735 0.265 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.734 0.266 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.733 0.267 0.000
Z45.1 Adjustment and management of infusion pump
0.733 0.267 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.733 0.267 0.000
C77.8 Lymph nodes of multiple regions
0.732 0.268 0.000
H43 Disorders of vitreous body
0.732 0.268 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.731 0.269 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.730 0.270 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.729 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.729 0.271 0.000
Z90.0 Acquired absence of part of head and neck
0.728 0.271 0.000
Z54 Convalescence
0.728 0.272 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.727 0.273 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.726 0.274 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
C16.4 Pylorus
0.724 0.276 0.000
T92.1 Sequelae of fracture of arm
0.723 0.277 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.723 0.277 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.723 0.277 0.000
Z12 Special screening examination for neoplasms
0.722 0.278 0.000
T23 Burn and corrosion of wrist and hand
0.722 0.278 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.721 0.279 0.000
B35.3 Tinea pedis
0.721 0.279 0.000
Y42.7 Androgens and anabolic congeners
0.721 0.279 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.720 0.280 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.719 0.281 0.000
C77.2 Intra-abdominal lymph nodes
0.718 0.282 0.000
T59 Toxic effect of other gases, fumes and vapours
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.717 0.283 0.000
C21 Malignant neoplasm of anus and anal canal
0.717 0.283 0.000
C17 Malignant neoplasm of small intestine
0.717 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.717 0.283 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Z51.6 Desensitisation to allergens
0.717 0.283 0.000
C18.8 Overlapping lesion of colon
0.717 0.283 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.717 0.283 0.000
H25.2 Senile cataract, morgagnian type
0.716 0.283 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.714 0.285 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
B25 Cytomegaloviral disease
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
C50.3 Lower-inner quadrant of breast
0.711 0.289 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.710 0.290 0.000
S50-S59 Injuries to the elbow and forearm
0.710 0.290 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.708 0.292 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.708 0.292 0.000
C32 Malignant neoplasm of larynx
0.708 0.292 0.000
C31 Malignant neoplasm of accessory sinuses
0.708 0.292 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.708 0.292 0.000
C37 Malignant neoplasm of thymus
0.708 0.292 0.000
C33 Malignant neoplasm of trachea
0.708 0.292 0.000
C18.3 Hepatic flexure
0.707 0.293 0.000
B02 Zoster [herpes zoster]
0.705 0.294 0.000
H10-H13 Disorders of conjunctiva
0.705 0.295 0.000
Z51.9 Medical care, unspecified
0.703 0.297 0.000
S61 Open wound of wrist and hand
0.702 0.298 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.702 0.298 0.000
C34.8 Overlapping lesion of bronchus and lung
0.701 0.299 0.000
C34.2 Middle lobe, bronchus or lung
0.701 0.299 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.700 0.300 0.000
C77.4 Inguinal and lower limb lymph nodes
0.700 0.300 0.000
C80 Malignant neoplasm without specification of site
0.699 0.301 0.000
Z40 Prophylactic surgery
0.699 0.301 0.000
H74 Other disorders of middle ear and mastoid
0.697 0.303 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.695 0.305 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
S90-S99 Injuries to the ankle and foot
0.691 0.309 0.000
H93 Other disorders of ear, not elsewhere classified
0.689 0.311 0.000
H71 Cholesteatoma of middle ear
0.687 0.313 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.687 0.313 0.000
Y54.4 Loop [high-ceiling] diuretics
0.687 0.313 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.687 0.313 0.000
Chapter X Diseases of the respiratory system
0.687 0.313 0.000
T98 Sequelae of other and unspecified effects of external causes
0.687 0.313 0.000
T95 Sequelae of burns, corrosions and frostbite
0.687 0.313 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.687 0.313 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.687 0.313 0.000
H42 Glaucoma in diseases classified elsewhere
0.686 0.314 0.000
T93 Sequelae of injuries of lower limb
0.685 0.315 0.000
B33 Other viral diseases, not elsewhere classified
0.685 0.315 0.000
B30 Viral conjunctivitis
0.685 0.315 0.000
B27 Infectious mononucleosis
0.685 0.315 0.000
B26 Mumps
0.685 0.315 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.684 0.316 0.000
C50.5 Lower-outer quadrant of breast
0.681 0.319 0.000
Z04.8 Examination and observation for other specified reasons
0.680 0.320 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.680 0.320 0.000
Z94.8 Other transplanted organ and tissue status
0.680 0.320 0.000
F43 Reaction to severe stress, and adjustment disorders
0.680 0.320 0.000
H26.3 Drug-induced cataract
0.679 0.321 0.000
H26.2 Complicated cataract
0.679 0.321 0.000
H26.1 Traumatic cataract
0.679 0.321 0.000
H26.0 Infantile, juvenile and presenile cataract
0.679 0.321 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.679 0.321 0.000
C15.9 Oesophagus, unspecified
0.679 0.321 0.000
B37.0 Candidal stomatitis
0.679 0.321 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.678 0.322 0.000
T87 Complications peculiar to reattachment and amputation
0.677 0.323 0.000
Z10 Routine general health check-up of defined subpopulation
0.676 0.324 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.676 0.324 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.675 0.325 0.000
C16.0 Cardia
0.675 0.325 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.674 0.326 0.000
C25.9 Pancreas, unspecified
0.674 0.326 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.674 0.326 0.000
M70-M79 Other soft tissue disorders
0.674 0.326 0.000
T94.1 Sequelae of injuries, not specified by body region
0.673 0.327 0.000
Z43.9 Attention to unspecified artificial opening
0.673 0.327 0.000
Z43.8 Attention to other artificial openings
0.673 0.327 0.000
Z43.7 Attention to artificial vagina
0.673 0.327 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.673 0.327 0.000
Z43.0 Attention to tracheostomy
0.673 0.327 0.000
C51-C58 Malignant neoplasms of female genital organs
0.673 0.327 0.000
Y59 Other and unspecified vaccines and biological substances
0.672 0.328 0.000
Y58 Bacterial vaccines
0.672 0.328 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.672 0.328 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.672 0.328 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.672 0.328 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.672 0.328 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.672 0.328 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.672 0.328 0.000
Z42 Follow-up care involving plastic surgery
0.671 0.329 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.670 0.330 0.000
H18.6 Keratoconus
0.669 0.331 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.669 0.331 0.000
Z46.8 Fitting and adjustment of other specified devices
0.669 0.331 0.000
C15.5 Lower third of oesophagus
0.669 0.331 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.668 0.332 0.000
H16 Keratitis
0.667 0.333 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.667 0.333 0.000
T40.8 Lysergide [LSD]
0.667 0.333 0.000
T40.7 Cannabis (derivatives)
0.667 0.333 0.000
T40.6 Other and unspecified narcotics
0.667 0.333 0.000
T40.5 Cocaine
0.667 0.333 0.000
T40.3 Methadone
0.667 0.333 0.000
T40.1 Heroin
0.667 0.333 0.000
T40.0 Opium
0.667 0.333 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.667 0.333 0.000
F60 Specific personality disorders
0.666 0.334 0.000
C78.2 Secondary malignant neoplasm of pleura
0.664 0.336 0.000
G82 Paraplegia and tetraplegia
0.664 0.336 0.000
H40.8 Other glaucoma
0.663 0.337 0.000
H40.6 Glaucoma secondary to drugs
0.663 0.337 0.000
H40.4 Glaucoma secondary to eye inflammation
0.663 0.337 0.000
H40.3 Glaucoma secondary to eye trauma
0.663 0.337 0.000
S32 Fracture of lumbar spine and pelvis
0.662 0.338 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.662 0.338 0.000
B34.8 Other viral infections of unspecified site
0.662 0.338 0.000
B34.4 Papovirus infection, unspecified
0.662 0.338 0.000
B34.3 Parvovirus infection, unspecified
0.662 0.338 0.000
B34.2 Coronavirus infection, unspecified
0.662 0.338 0.000
B34.1 Enterovirus infection, unspecified
0.662 0.338 0.000
B34.0 Adenovirus infection, unspecified
0.662 0.338 0.000
H46 Optic neuritis
0.661 0.338 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.660 0.340 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.660 0.340 0.000
Z28 Immunisation not carried out
0.660 0.340 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.660 0.340 0.000
Z26 Need for immunisation against other single infectious diseases
0.660 0.340 0.000
Z25 Need for immunisation against other single viral diseases
0.660 0.340 0.000
Z24 Need for immunisation against certain single viral diseases
0.660 0.340 0.000
Z23 Need for immunisation against single bacterial diseases
0.660 0.340 0.000
Z20 Contact with and exposure to communicable diseases
0.660 0.340 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.660 0.340 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.659 0.341 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.659 0.341 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.659 0.341 0.000
T42.3 Barbiturates
0.659 0.341 0.000
T42.2 Succinimides and oxazolidinediones
0.659 0.341 0.000
T42.1 Iminostilbenes
0.659 0.341 0.000
T42.0 Hydantoin derivatives
0.659 0.341 0.000
T66-T78 Other and unspecified effects of external causes
0.658 0.342 0.000
G90-G99 Other disorders of the nervous system
0.656 0.344 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.656 0.344 0.000
B02.9 Zoster without complication
0.656 0.344 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.655 0.345 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.655 0.345 0.000
Z94.6 Bone transplant status
0.655 0.345 0.000
Z94.5 Skin transplant status
0.655 0.345 0.000
Z94.3 Heart and lungs transplant status
0.655 0.345 0.000
Z94.2 Lung transplant status
0.655 0.345 0.000
Z94.1 Heart transplant status
0.655 0.345 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.654 0.346 0.000
T39.4 Antirheumatics, not elsewhere classified
0.654 0.346 0.000
T39.2 Pyrazolone derivatives
0.654 0.346 0.000
C78.7 Secondary malignant neoplasm of liver
0.654 0.346 0.000
H55-H59 Other disorders of eye and adnexa
0.653 0.346 0.000
M79.8 Other specified soft tissue disorders
0.653 0.347 0.000
B48 Other mycoses, not elsewhere classified
0.651 0.348 0.000
B47 Mycetoma
0.651 0.348 0.000
B46 Zygomycosis
0.651 0.348 0.000
B45 Cryptococcosis
0.651 0.348 0.000
B43 Chromomycosis and phaeomycotic abscess
0.651 0.348 0.000
B42 Sporotrichosis
0.651 0.348 0.000
B41 Paracoccidioidomycosis
0.651 0.348 0.000
B40 Blastomycosis
0.651 0.348 0.000
B39 Histoplasmosis
0.651 0.348 0.000
B38 Coccidioidomycosis
0.651 0.348 0.000
B36 Other superficial mycoses
0.651 0.348 0.000
B49 Unspecified mycosis
0.651 0.348 0.000
T43.2 Other and unspecified antidepressants
0.650 0.350 0.000
T91.3 Sequelae of injury of spinal cord
0.649 0.351 0.000
Y43.3 Other antineoplastic drugs
0.648 0.352 0.000
Z11.2 Special screening examination for other bacterial diseases
0.647 0.353 0.000
H47.3 Other disorders of optic disk
0.647 0.353 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.647 0.353 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.647 0.353 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.647 0.353 0.000
T82.3 Mechanical complication of other vascular grafts
0.647 0.353 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.647 0.353 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.647 0.353 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.646 0.354 0.000
H44 Disorders of globe
0.646 0.354 0.000
Z29.1 Prophylactic immunotherapy
0.645 0.354 0.000
Z48 Other surgical follow-up care
0.645 0.355 0.000
A00-A09 Intestinal infectious diseases
0.645 0.355 0.000
D37.4 Colon
0.644 0.356 0.000
C43.5 Malignant melanoma of trunk
0.644 0.356 0.000
C78.0 Secondary malignant neoplasm of lung
0.644 0.356 0.000
Z11.5 Special screening examination for other viral diseases
0.644 0.356 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.643 0.356 0.000
Y54.3 Benzothiadiazine derivatives
0.643 0.356 0.000
F99-F99 Unspecified mental disorder
0.643 0.357 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.643 0.357 0.000
Z87.8 Personal history of other specified conditions
0.642 0.358 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.642 0.358 0.000
T39.0 Salicylates
0.641 0.358 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.641 0.359 0.000
H90 Conductive and sensorineural hearing loss
0.641 0.359 0.000
Z89 Acquired absence of limb
0.641 0.359 0.000
T59.8 Other specified gases, fumes and vapours
0.641 0.359 0.000
D10-D36 Benign neoplasms
0.640 0.360 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.640 0.360 0.000
Z45.3 Adjustment and management of implanted hearing device
0.640 0.360 0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.640 0.360 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.640 0.360 0.000
Z41 Procedures for purposes other than remedying health state
0.638 0.362 0.000
V10-V19 Pedal cyclist injured in transport accident
0.638 0.362 0.000
Z22.3 Carrier of other specified bacterial diseases
0.637 0.363 0.000
H53-H54 Visual disturbances and blindness
0.636 0.364 0.000
S19 Other and unspecified injuries of neck
0.636 0.364 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.636 0.364 0.000
H40.5 Glaucoma secondary to other eye disorders
0.635 0.365 0.000
Z83.6 Family history of diseases of the respiratory system
0.634 0.366 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.634 0.366 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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