TreeWAS – Variant ID: rs114425975

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
E10 Insulin-dependent diabetes mellitus	0.999	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.997	0.003
E10.9 Without complications	0.991	0.009
Chapter I Certain infectious and parasitic diseases	0.990	0.010
D37-D48 Neoplasms of uncertain or unknown behaviour	0.987	0.013
C64-C68 Malignant neoplasms of urinary tract	0.984	0.016
C79 Secondary malignant neoplasm of other sites	0.983	0.017
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.982	0.018
B95-B98 Bacterial, viral and other infectious agents	0.982	0.018
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.975	0.025
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.974	0.026
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.970	0.030
C51-C58 Malignant neoplasms of female genital organs	0.968	0.032
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.956	0.044
C34 Malignant neoplasm of bronchus and lung	0.954	0.046
C67 Malignant neoplasm of bladder	0.952	0.048
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.951	0.049
S40-S49 Injuries to the shoulder and upper arm	0.946	0.054
M05-M14 Inflammatory polyarthropathies	0.946	0.054
C54 Malignant neoplasm of corpus uteri	0.939	0.061
E50-E64 Other nutritional deficiencies	0.933	0.067
M06 Other rheumatoid arthritis	0.927	0.073
E10.5 With peripheral circulatory complications	0.925	0.075
E65-E68 Obesity and other hyperalimentation	0.925	0.075
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.921	0.079
E10.4 With neurological complications	0.920	0.080
M50-M54 Other dorsopathies	0.919	0.081
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.919	0.081
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.917	0.083
M06.9 Rheumatoid arthritis, unspecified	0.912	0.088
C64 Malignant neoplasm of kidney, except renal pelvis	0.908	0.092
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.905	0.095
C54.1 Endometrium	0.905	0.095
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.901	0.099
C34.9 Bronchus or lung, unspecified	0.892	0.108
D46 Myelodysplastic syndromes	0.889	0.111
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.882	0.118
C79.8 Secondary malignant neoplasm of other specified sites	0.881	0.119
D41.4 Bladder	0.879	0.121
Chapter V Mental and behavioural disorders	0.879	0.121
T66-T78 Other and unspecified effects of external causes	0.878	0.122
E14 Unspecified diabetes mellitus	0.878	0.122
C34.3 Lower lobe, bronchus or lung	0.877	0.123
S42 Fracture of shoulder and upper arm	0.875	0.125
E66 Obesity	0.871	0.129
S20-S29 Injuries to the thorax	0.868	0.132
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.867	0.133
C78.2 Secondary malignant neoplasm of pleura	0.861	0.139
S49 Other and unspecified injuries of shoulder and upper arm	0.854	0.146
T20-T25 Burns and corrosions of external body surface, specified by site	0.851	0.149
S10-S19 Injuries to the neck	0.849	0.151
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.848	0.152
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.847	0.153
Chapter XXII Codes for special purposes	0.845	0.155
C67.9 Bladder, unspecified	0.845	0.155
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.845	0.155
C56 Malignant neoplasm of ovary	0.844	0.156
M53 Other dorsopathies, not elsewhere classified	0.838	0.162
M86-M90 Other osteopathies	0.838	0.162
E40-E46 Malnutrition	0.837	0.163
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.837	0.163
E16 Other disorders of pancreatic internal secretion	0.836	0.164
M80-M85 Disorders of bone density and structure	0.836	0.164
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.833	0.167
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.831	0.169
C80 Malignant neoplasm without specification of site	0.830	0.170
C78.0 Secondary malignant neoplasm of lung	0.823	0.177
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.822	0.178
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.822	0.178
F00-F09 Organic, including symptomatic, mental disorders	0.818	0.182
D46.9 Myelodysplastic syndrome, unspecified	0.818	0.182
E10.2 With renal complications	0.817	0.183
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.812	0.188
B35-B49 Mycoses	0.810	0.190
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.809	0.191
M65-M68 Disorders of synovium and tendon	0.809	0.191
E55 Vitamin D deficiency	0.806	0.194
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.806	0.194
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.804	0.196
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.804	0.196
E53 Deficiency of other B group vitamins	0.803	0.197
Chapter XX External causes of morbidity and mortality	0.801	0.199
B20-B24 Human immunodeficiency virus [HIV] disease	0.795	0.205
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.795	0.205
A80-A89 Viral infections of the central nervous system	0.792	0.208
C79.6 Secondary malignant neoplasm of ovary	0.792	0.208
C67.0 Trigone of bladder	0.791	0.209
E66.9 Obesity, unspecified	0.790	0.210
S49.9 Unspecified injury of shoulder and upper arm	0.789	0.211
C67.8 Overlapping lesion of bladder	0.788	0.212
C54.9 Corpus uteri, unspecified	0.785	0.215
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.782	0.218
C78.1 Secondary malignant neoplasm of mediastinum	0.782	0.218
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.781	0.219
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.781	0.219
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.779	0.221
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.776	0.224
E11 Non-insulin-dependent diabetes mellitus	0.775	0.225
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.774	0.225
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.773	0.227
S42.3 Fracture of shaft of humerus	0.773	0.227
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.771	0.229
C38 Malignant neoplasm of heart, mediastinum and pleura	0.768	0.232
S27 Injury of other and unspecified intrathoracic organs	0.765	0.235
Y95 Nosocomial condition	0.765	0.235
C67.4 Posterior wall of bladder	0.764	0.236
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.763	0.237
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.763	0.237
E10.1 With ketoacidosis	0.763	0.237
C67.6 Ureteric orifice	0.762	0.238
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.760	0.240
T78 Adverse effects, not elsewhere classified	0.760	0.240
E14.4 With neurological complications	0.755	0.245
S70-S79 Injuries to the hip and thigh	0.754	0.246
M60-M63 Disorders of muscles	0.754	0.246
M50 Cervical disk disorders	0.752	0.248
M51 Other intervertebral disk disorders	0.751	0.249
E10.8 With unspecified complications	0.750	0.250
M05 Seropositive rheumatoid arthritis	0.748	0.252
E66.8 Other obesity	0.746	0.254
Chapter VII Diseases of the eye and adnexa	0.743	0.257
B25-B34 Other viral diseases	0.743	0.257
S90-S99 Injuries to the ankle and foot	0.743	0.257
D38.1 Trachea, bronchus and lung	0.743	0.257
E14.3 With ophthalmic complications	0.742	0.258
C52 Malignant neoplasm of vagina	0.741	0.258
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.741	0.259
E00-E07 Disorders of thyroid gland	0.741	0.259
E16.2 Hypoglycaemia, unspecified	0.740	0.260
T20 Burn and corrosion of head and neck	0.737	0.263
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.737	0.263
S12 Fracture of neck	0.735	0.265
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.734	0.266
C67.1 Dome of bladder	0.734	0.266
T68 Hypothermia	0.734	0.266
B99-B99 Other infectious diseases	0.731	0.269
F60-F69 Disorders of adult personality and behaviour	0.730	0.270
S40 Superficial injury of shoulder and upper arm	0.729	0.271
E61 Deficiency of other nutrient elements	0.729	0.271
F99-F99 Unspecified mental disorder	0.729	0.271
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.728	0.272
T15-T19 Effects of foreign body entering through natural orifice	0.728	0.272
M96.8 Other postprocedural musculoskeletal disorders	0.728	0.272
S42.4 Fracture of lower end of humerus	0.727	0.273
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.723	0.277
C78.4 Secondary malignant neoplasm of small intestine	0.722	0.277
M06.3 Rheumatoid nodule	0.722	0.278
S22 Fracture of rib(s), sternum and thoracic spine	0.722	0.278
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.722	0.278
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.721	0.279
E46 Unspecified protein-energy malnutrition	0.720	0.280
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.718	0.281
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.718	0.282
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
M11 Other crystal arthropathies	0.717	0.283
E10.7 With multiple complications	0.716	0.284
E10.6 With other specified complications	0.716	0.284
E10.0 With coma	0.716	0.284
E55.9 Vitamin D deficiency, unspecified	0.715	0.285
C76 Malignant neoplasm of other and ill-defined sites	0.715	0.285
H53-H54 Visual disturbances and blindness	0.712	0.288
M87 Osteonecrosis	0.711	0.288
E53.8 Deficiency of other specified B group vitamins	0.710	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.290
B50-B64 Protozoal diseases	0.710	0.290
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.710	0.290
A75-A79 Rickettsioses	0.710	0.290
A70-A74 Other diseases caused by chlamydiae	0.710	0.290
A65-A69 Other spirochaetal diseases	0.710	0.290
A20-A28 Certain zoonotic bacterial diseases	0.710	0.290
A15-A19 Tuberculosis	0.710	0.290
B15-B19 Viral hepatitis	0.709	0.291
C34.2 Middle lobe, bronchus or lung	0.709	0.291
B65-B83 Helminthiases	0.708	0.292
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.708	0.292
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.708	0.292
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.707	0.293
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.706	0.294
T79-T79 Certain early complications of trauma	0.706	0.294
C68 Malignant neoplasm of other and unspecified urinary organs	0.705	0.294
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.705	0.295
C34.0 Main bronchus	0.704	0.296
C90 Multiple myeloma and malignant plasma cell neoplasms	0.701	0.299
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.700	0.300
S42.30 Fracture of shaft of humerus (closed)	0.699	0.301
S27.0 Traumatic pneumothorax	0.699	0.301
T33-T35 Frostbite	0.699	0.301
T26-T28 Burns and corrosions confined to eye and internal organs	0.699	0.301
T00-T07 Injuries involving multiple body regions	0.699	0.301
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.698	0.302
C31 Malignant neoplasm of accessory sinuses	0.698	0.302
C30 Malignant neoplasm of nasal cavity and middle ear	0.698	0.302
C37 Malignant neoplasm of thymus	0.698	0.302
C33 Malignant neoplasm of trachea	0.698	0.302
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.698	0.302
M95.0 Acquired deformity of nose	0.698	0.302
E11.5 With peripheral circulatory complications	0.698	0.302
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.697	0.303
C51 Malignant neoplasm of vulva	0.696	0.304
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.695	0.304
F05 Delirium, not induced by alcohol and other psychoactive substances	0.696	0.304
C80.9 Malignant neoplasm, unspecified	0.695	0.305
M40-M43 Deforming dorsopathies	0.695	0.305
C57 Malignant neoplasm of other and unspecified female genital organs	0.694	0.306
C58 Malignant neoplasm of placenta	0.694	0.306
T58 Toxic effect of carbon monoxide	0.694	0.306
E13 Other specified diabetes mellitus	0.693	0.307
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.692	0.308
M81 Osteoporosis without pathological fracture	0.692	0.308
C34.1 Upper lobe, bronchus or lung	0.691	0.309
H54 Blindness and low vision	0.691	0.309
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.687	0.313
B90-B94 Sequelae of infectious and parasitic diseases	0.687	0.313
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.685	0.315
E16.1 Other hypoglycaemia	0.685	0.315
C34.8 Overlapping lesion of bronchus and lung	0.684	0.316
C65 Malignant neoplasm of renal pelvis	0.683	0.316
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.683	0.317
T78.4 Allergy, unspecified	0.683	0.317
C67.7 Urachus	0.683	0.317
D00-D09 In situ neoplasms	0.682	0.318
M50.0 Cervical disk disorder with myelopathy	0.682	0.318
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.682	0.318
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.682	0.318
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.682	0.318
S42.7 Multiple fractures of clavicle, scapula and humerus	0.679	0.320
M00-M03 Infectious arthropathies	0.679	0.321
S48 Traumatic amputation of shoulder and upper arm	0.678	0.322
S45 Injury of blood vessels at shoulder and upper arm level	0.678	0.322
S44 Injury of nerves at shoulder and upper arm level	0.678	0.322
S47 Crushing injury of shoulder and upper arm	0.678	0.322
M12 Other specific arthropathies	0.678	0.322
M09 Juvenile arthritis in diseases classified elsewhere	0.678	0.322
M08 Juvenile arthritis	0.678	0.322
F06.7 Mild cognitive disorder	0.678	0.322
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.678	0.322
B37 Candidiasis	0.675	0.325
C54.8 Overlapping lesion of corpus uteri	0.674	0.326
C54.3 Fundus uteri	0.674	0.326
C54.2 Myometrium	0.674	0.326
C54.0 Isthmus uteri	0.674	0.326
M65 Synovitis and tenosynovitis	0.673	0.327
M14 Arthropathies in other diseases classified elsewhere	0.672	0.327
S19 Other and unspecified injuries of neck	0.672	0.328
T65 Toxic effect of other and unspecified substances	0.672	0.328
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.672	0.328
M86 Osteomyelitis	0.671	0.329
T36-T50 Poisoning by drugs, medicaments and biological substances	0.671	0.329
B02 Zoster [herpes zoster]	0.670	0.330
E64 Sequelae of malnutrition and other nutritional deficiencies	0.669	0.331
E63 Other nutritional deficiencies	0.669	0.331
E56 Other vitamin deficiencies	0.669	0.331
E51 Thiamine deficiency	0.669	0.331
E50 Vitamin A deficiency	0.669	0.331
E60 Dietary zinc deficiency	0.669	0.331
E59 Dietary selenium deficiency	0.669	0.331
E58 Dietary calcium deficiency	0.669	0.331
E54 Ascorbic acid deficiency	0.669	0.331
E52 Niacin deficiency [pellagra]	0.669	0.331
E65 Localised adiposity	0.667	0.333
M84 Disorders of continuity of bone	0.666	0.334
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.666	0.334
C79.2 Secondary malignant neoplasm of skin	0.666	0.334
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.666	0.334
S50-S59 Injuries to the elbow and forearm	0.665	0.335
M06.8 Other specified rheumatoid arthritis	0.664	0.336
M06.4 Inflammatory polyarthropathy	0.664	0.336
M06.2 Rheumatoid bursitis	0.664	0.336
M06.1 Adult-onset Still's disease	0.664	0.336
E67 Other hyperalimentation	0.663	0.337
E68 Sequelae of hyperalimentation	0.663	0.337
C88 Malignant immunoproliferative diseases	0.662	0.338
T23 Burn and corrosion of wrist and hand	0.662	0.338
Q00-Q07 Congenital malformations of the nervous system	0.661	0.339
E11.0 With coma	0.661	0.339
H54.0 Blindness, both eyes	0.660	0.340
D80-D89 Certain disorders involving the immune mechanism	0.660	0.340
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.659	0.341
D41.9 Urinary organ, unspecified	0.659	0.341
D41.7 Other urinary organs	0.659	0.341
D41.3 Urethra	0.659	0.341
D41.2 Ureter	0.659	0.341
D41.1 Renal pelvis	0.659	0.341
M99 Biomechanical lesions, not elsewhere classified	0.658	0.342
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.658	0.342
F70-F79 Mental retardation	0.657	0.343
M51.9 Intervertebral disk disorder, unspecified	0.656	0.343
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.656	0.344
W20-W49 Exposure to inanimate mechanical forces	0.656	0.344
B24 Unspecified human immunodeficiency virus [HIV] disease	0.655	0.344
M06.98 Rheumatoid arthritis, unspecified (Other)	0.654	0.346
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.654	0.346
M90 Osteopathies in diseases classified elsewhere	0.653	0.346
M07 Psoriatic and enteropathic arthropathies	0.653	0.347
C67.5 Bladder neck	0.653	0.347
S29 Other and unspecified injuries of thorax	0.652	0.348
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.652	0.348
D04 Carcinoma in situ of skin	0.651	0.349
S41 Open wound of shoulder and upper arm	0.651	0.349
F80-F89 Disorders of psychological development	0.650	0.350
C67.2 Lateral wall of bladder	0.649	0.351
E16.0 Drug-induced hypoglycaemia without coma	0.649	0.351
S46 Injury of muscle and tendon at shoulder and upper arm level	0.649	0.351
E15 Nondiabetic hypoglycaemic coma	0.649	0.351
M95.4 Acquired deformity of chest and rib	0.648	0.352
S42.1 Fracture of scapula	0.648	0.352
D48.6 Breast	0.648	0.352
T78.2 Anaphylactic shock, unspecified	0.647	0.353
T51 Toxic effect of alcohol	0.646	0.354
E20-E35 Disorders of other endocrine glands	0.645	0.355
M50.9 Cervical disk disorder, unspecified	0.644	0.356
C67.3 Anterior wall of bladder	0.643	0.357
S42.2 Fracture of upper end of humerus	0.642	0.358
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.640	0.359
C66 Malignant neoplasm of ureter	0.640	0.360
C92 Myeloid leukaemia	0.638	0.362
E04 Other non-toxic goitre	0.638	0.362
D46.7 Other myelodysplastic syndromes	0.637	0.363
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.637	0.363
D46.5 Refractory anaemia with multi-lineage dysplasia	0.637	0.363
D46.4 Refractory anaemia, unspecified	0.637	0.363
D46.3 Refractory anaemia with excess of blasts with transformation	0.637	0.363
D46.2 Refractory anaemia with excess of blasts	0.637	0.363
D46.1 Refractory anaemia with sideroblasts	0.637	0.363
D46.0 Refractory anaemia without sideroblasts, so stated	0.637	0.363
M51.8 Other specified intervertebral disk disorders	0.636	0.364
D86 Sarcoidosis	0.636	0.364
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.635	0.364
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.635	0.365
E66.0 Obesity due to excess calories	0.633	0.367
Q20-Q28 Congenital malformations of the circulatory system	0.633	0.367
C32 Malignant neoplasm of larynx	0.632	0.368
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.631	0.369
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.630	0.370
T75 Effects of other external causes	0.630	0.370
T74 Maltreatment syndromes	0.630	0.370
T73 Effects of other deprivation	0.630	0.370
T70 Effects of air pressure and water pressure	0.630	0.370
T69 Other effects of reduced temperature	0.630	0.370
T67 Effects of heat and light	0.630	0.370
T71 Asphyxiation	0.630	0.370
T66 Unspecified effects of radiation	0.630	0.370
E14.8 With unspecified complications	0.629	0.370
E14.7 With multiple complications	0.629	0.370
E14.6 With other specified complications	0.629	0.370
E14.5 With peripheral circulatory complications	0.629	0.370
E14.2 Withrenal complications	0.629	0.370
E14.1 With ketoacidosis	0.629	0.370
E14.0 With coma	0.629	0.370
D48.1 Connective and other soft tissue	0.629	0.370
B97 Viral agents as the cause of diseases classified to other chapters	0.629	0.371
T11 Other injuries of upper limb, level unspecified	0.629	0.371
M80 Osteoporosis with pathological fracture	0.629	0.371
Chapter VIII Diseases of the ear and mastoid process	0.628	0.372
S42.8 Fracture of other parts of shoulder and upper arm	0.627	0.373
D43.0 Brain, supratentorial	0.627	0.373
A86 Unspecified viral encephalitis	0.627	0.373
F60 Specific personality disorders	0.624	0.376
E66.2 Extreme obesity with alveolar hypoventilation	0.624	0.376
E66.1 Drug-induced obesity	0.624	0.376
S71 Open wound of hip and thigh	0.624	0.376
A50-A64 Infections with a predominantly sexual mode of transmission	0.623	0.377
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.622	0.378
S26 Injury of heart	0.622	0.378
S25 Injury of blood vessels of thorax	0.622	0.378
S24 Injury of nerves and spinal cord at thorax level	0.622	0.378
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.622	0.378
S21 Open wound of thorax	0.622	0.378
S42.40 Fracture of lower end of humerus (closed)	0.622	0.378
H54.9 Unspecified visual impairment (binocular)	0.622	0.378
S14 Injury of nerves and spinal cord at neck level	0.622	0.378
E10.3 With ophthalmic complications	0.621	0.378
F99 Mental disorder, not otherwise specified	0.621	0.379
C80.0 Malignant neoplasm, primary site unknown, so stated	0.621	0.379
C38.4 Pleura	0.620	0.380
S42.9 Fracture of shoulder girdle, part unspecified	0.620	0.380
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.619	0.381
M06.0 Seronegative rheumatoid arthritis	0.618	0.382
T20.0 Burn of unspecified degree of head and neck	0.618	0.382
X20-X29 Contact with venomous animals and plants	0.614	0.385
H21 Other disorders of iris and ciliary body	0.614	0.386
S49.8 Other specified injuries of shoulder and upper arm	0.612	0.387
S49.7 Multiple injuries of shoulder and upper arm	0.612	0.387
V40-V49 Car occupant injured in transport accident	0.612	0.388
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.611	0.389
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.611	0.389
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.611	0.389
T25 Burn and corrosion of ankle and foot	0.610	0.390
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.610	0.390
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.610	0.390
T21 Burn and corrosion of trunk	0.610	0.390
S12.9 Fracture of neck, part unspecified	0.609	0.391
S17 Crushing injury of neck	0.608	0.391
S15 Injury of blood vessels at neck level	0.608	0.391
S11 Open wound of neck	0.608	0.391
S18 Traumatic amputation at neck level	0.608	0.391
S16 Injury of muscle and tendon at neck level	0.608	0.391
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.608	0.392
B44 Aspergillosis	0.608	0.392
C81 Hodgkin's disease	0.607	0.393
M05.9 Seropositive rheumatoid arthritis, unspecified	0.607	0.393
D04.3 Skin of other and unspecified parts of face	0.606	0.394
D38.6 Respiratory organ, unspecified	0.606	0.394
D38.5 Other respiratory organs	0.606	0.394
D38.4 Thymus	0.606	0.394
D38.3 Mediastinum	0.606	0.394
D38.2 Pleura	0.606	0.394
D38.0 Larynx	0.606	0.394
D48.0 Bone and articular cartilage	0.604	0.395
H20 Iridocyclitis	0.604	0.396
C79.9 Secondary malignant neoplasm, unspecified site	0.604	0.396
S10 Superficial injury of neck	0.603	0.397
M87.9 Osteonecrosis, unspecified	0.603	0.397
C71 Malignant neoplasm of brain	0.603	0.397
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.602	0.398
M53.9 Dorsopathy, unspecified	0.601	0.399
M53.8 Other specified dorsopathies	0.601	0.399
M53.2 Spinal instabilities	0.601	0.399
M53.1 Cervicobrachial syndrome	0.601	0.399
M53.0 Cervicocranial syndrome	0.601	0.399
A87 Viral meningitis	0.601	0.399
D41.0 Kidney	0.600	0.400
E44 Protein-energy malnutrition of moderate and mild degree	0.600	0.400
E45 Retarded development following protein-energy malnutrition	0.600	0.400
E43 Unspecified severe protein-energy malnutrition	0.600	0.400
E42 Marasmic kwashiorkor	0.600	0.400
E41 Nutritional marasmus	0.600	0.400
E40 Kwashiorkor	0.600	0.400
M67 Other disorders of synovium and tendon	0.600	0.400
T62 Toxic effect of other noxious substances eaten as food	0.600	0.400
T61 Toxic effect of noxious substances eaten as seafood	0.600	0.400
T60 Toxic effect of pesticides	0.600	0.400
T57 Toxic effect of other inorganic substances	0.600	0.400
T56 Toxic effect of metals	0.600	0.400
T54 Toxic effect of corrosive substances	0.600	0.400
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.600	0.400
T52 Toxic effect of organic solvents	0.600	0.400
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.600	0.400
T55 Toxic effect of soaps and detergents	0.600	0.400
E16.9 Disorder of pancreatic internal secretion, unspecified	0.600	0.400
E16.8 Other specified disorders of pancreatic internal secretion	0.600	0.400
E16.4 Abnormal secretion of gastrin	0.600	0.400
E16.3 Increased secretion of glucagon	0.600	0.400
M83 Adult osteomalacia	0.599	0.400
S12.2 Fracture of other specified cervical vertebra	0.599	0.400
C95 Leukaemia of unspecified cell type	0.598	0.402
W50-W64 Exposure to animate mechanical forces	0.598	0.402
X60-X84 Intentional self-harm	0.596	0.403
C90.0 Multiple myeloma	0.596	0.404
M91-M94 Chondropathies	0.596	0.404
T20.2 Burn of second degree of head and neck	0.595	0.405
C53 Malignant neoplasm of cervix uteri	0.593	0.407
M06.37 Rheumatoid nodule (Ankle and foot)	0.593	0.407
M85 Other disorders of bone density and structure	0.592	0.407
C84 Peripheral and cutaneous T-cell lymphomas	0.592	0.408
T14 Injury of unspecified body region	0.591	0.409
C79.7 Secondary malignant neoplasm of adrenal gland	0.591	0.409
M62 Other disorders of muscle	0.590	0.410
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.590	0.410
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.590	0.410
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.589	0.411
X50-X57 Overexertion, travel and privation	0.589	0.411
Y00-Y09 Assault	0.588	0.411
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.587	0.413
F02 Dementia in other diseases classified elsewhere	0.587	0.413
F09 Unspecified organic or symptomatic mental disorder	0.587	0.413
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.587	0.413
U80 Agent resistant to penicillin and related antibiotics	0.586	0.414
D37.0 Lip, oral cavity and pharynx	0.584	0.416
E04.1 Non-toxic single thyroid nodule	0.583	0.417
S70 Superficial injury of hip and thigh	0.583	0.417
T63 Toxic effect of contact with venomous animals	0.583	0.417
E61.1 Iron deficiency	0.583	0.417
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.583	0.417
Q35-Q37 Cleft lip and cleft palate	0.583	0.417
Q30-Q34 Congenital malformations of the respiratory system	0.583	0.417
D86.9 Sarcoidosis, unspecified	0.582	0.418
E11.8 With unspecified complications	0.582	0.418
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.582	0.418
B48 Other mycoses, not elsewhere classified	0.581	0.419
B47 Mycetoma	0.581	0.419
B46 Zygomycosis	0.581	0.419
B45 Cryptococcosis	0.581	0.419
B43 Chromomycosis and phaeomycotic abscess	0.581	0.419
B42 Sporotrichosis	0.581	0.419
B41 Paracoccidioidomycosis	0.581	0.419
B40 Blastomycosis	0.581	0.419
B39 Histoplasmosis	0.581	0.419
B38 Coccidioidomycosis	0.581	0.419
B36 Other superficial mycoses	0.581	0.419
B49 Unspecified mycosis	0.581	0.419
D45 Polycythaemia vera	0.581	0.419
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.580	0.420

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations