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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114439515
log Bayes Factor = 1.19568
Chromosome 4   position 57,676,403  (GRCh37) Explore rs114439515 on Ensembl!
Variant rs114439515 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
0.932 0.068 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.932 0.068 0.000
# Top node
0.917 0.083 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.899 0.101 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.898 0.102 0.000
M20-M25 Other joint disorders
0.895 0.105 0.000
M23 Internal derangement of knee
0.891 0.109 0.000
Chapter XIV Diseases of the genitourinary system
0.888 0.112 0.000
C79 Secondary malignant neoplasm of other sites
0.880 0.120 0.000
Chapter VIII Diseases of the ear and mastoid process
0.873 0.127 0.000
C60-C63 Malignant neoplasms of male genital organs
0.871 0.129 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.869 0.131 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.868 0.132 0.000
Chapter I Certain infectious and parasitic diseases
0.867 0.133 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.863 0.137 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.837 0.163 0.000
N10-N16 Renal tubulo-interstitial diseases
0.833 0.167 0.000
H65-H75 Diseases of middle ear and mastoid
0.829 0.171 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.828 0.172 0.000
C77.2 Intra-abdominal lymph nodes
0.826 0.174 0.000
C61 Malignant neoplasm of prostate
0.821 0.179 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.821 0.179 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.817 0.183 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.814 0.186 0.000
M23.3 Other meniscus derangements
0.810 0.190 0.000
C51-C58 Malignant neoplasms of female genital organs
0.808 0.192 0.000
N13 Obstructive and reflux uropathy
0.807 0.193 0.000
D00-D09 In situ neoplasms
0.798 0.202 0.000
A30-A49 Other bacterial diseases
0.796 0.204 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.792 0.208 0.000
C77.5 Intrapelvic lymph nodes
0.789 0.211 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.786 0.214 0.000
C79.2 Secondary malignant neoplasm of skin
0.783 0.217 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.782 0.218 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.781 0.219 0.000
Chapter VI Diseases of the nervous system
0.780 0.220 0.000
B35-B49 Mycoses
0.774 0.226 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.773 0.227 0.000
C15-C26 Malignant neoplasms of digestive organs
0.766 0.234 0.000
Chapter IX Diseases of the circulatory system
0.760 0.240 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.758 0.242 0.000
G90-G99 Other disorders of the nervous system
0.749 0.251 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.744 0.256 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.743 0.257 0.000
N00-N08 Glomerular diseases
0.742 0.258 0.000
N85.2 Hypertrophy of uterus
0.739 0.261 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.736 0.264 0.000
I20-I25 Ischaemic heart diseases
0.736 0.264 0.000
C54 Malignant neoplasm of corpus uteri
0.736 0.264 0.000
I95 Hypotension
0.733 0.267 0.000
C77.8 Lymph nodes of multiple regions
0.732 0.268 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.727 0.273 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.725 0.275 0.000
B95-B98 Bacterial, viral and other infectious agents
0.723 0.277 0.000
M25 Other joint disorders, not elsewhere classified
0.722 0.278 0.000
I95.9 Hypotension, unspecified
0.718 0.282 0.000
Chapter VII Diseases of the eye and adnexa
0.717 0.283 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.716 0.284 0.000
A41 Other septicaemia
0.715 0.285 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.715 0.285 0.000
C77.9 Lymph node, unspecified
0.714 0.286 0.000
M45-M49 Spondylopathies
0.711 0.289 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.709 0.291 0.000
N83.1 Corpus luteum cyst
0.708 0.292 0.000
B37 Candidiasis
0.707 0.293 0.000
C64-C68 Malignant neoplasms of urinary tract
0.707 0.293 0.000
H60-H62 Diseases of external ear
0.707 0.293 0.000
M23.5 Chronic instability of knee
0.705 0.294 0.000
D06 Carcinoma in situ of cervix uteri
0.705 0.295 0.000
H66 Suppurative and unspecified otitis media
0.704 0.296 0.000
H65 Nonsuppurative otitis media
0.704 0.296 0.000
M23.4 Loose body in knee
0.703 0.296 0.000
C78.7 Secondary malignant neoplasm of liver
0.702 0.298 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.701 0.299 0.000
N87 Dysplasia of cervix uteri
0.700 0.300 0.000
M34 Systemic sclerosis
0.698 0.302 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.696 0.304 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
M80-M85 Disorders of bone density and structure
0.694 0.306 0.000
N13.8 Other obstructive and reflux uropathy
0.693 0.307 0.000
N83.2 Other and unspecified ovarian cysts
0.692 0.308 0.000
G93 Other disorders of brain
0.692 0.308 0.000
N94.1 Dyspareunia
0.691 0.309 0.000
M23.8 Other internal derangements of knee
0.690 0.310 0.000
C80 Malignant neoplasm without specification of site
0.687 0.312 0.000
N85.4 Malposition of uterus
0.685 0.315 0.000
C54.1 Endometrium
0.684 0.316 0.000
M22 Disorders of patella
0.684 0.316 0.000
B25-B34 Other viral diseases
0.678 0.322 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.677 0.323 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.676 0.324 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.674 0.326 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.670 0.330 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.670 0.330 0.000
I25 Chronic ischaemic heart disease
0.669 0.331 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.668 0.332 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.668 0.332 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.668 0.332 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.668 0.332 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.667 0.332 0.000
N13.6 Pyonephrosis
0.667 0.333 0.000
N90.4 Leukoplakia of vulva
0.667 0.333 0.000
A41.9 Septicaemia, unspecified
0.667 0.333 0.000
N70 Salpingitis and oophoritis
0.666 0.334 0.000
H74 Other disorders of middle ear and mastoid
0.666 0.334 0.000
S00-S09 Injuries to the head
0.666 0.334 0.000
M25.5 Pain in joint
0.665 0.335 0.000
N88 Other noninflammatory disorders of cervix uteri
0.664 0.336 0.000
M31 Other necrotising vasculopathies
0.661 0.338 0.000
N17-N19 Renal failure
0.661 0.339 0.000
N85.0 Endometrial glandular hyperplasia
0.661 0.339 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.660 0.340 0.000
M91-M94 Chondropathies
0.660 0.340 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.660 0.340 0.000
Chapter XXII Codes for special purposes
0.659 0.341 0.000
M50-M54 Other dorsopathies
0.658 0.342 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.657 0.342 0.000
M65-M68 Disorders of synovium and tendon
0.657 0.343 0.000
M24 Other specific joint derangements
0.656 0.343 0.000
A49 Bacterial infection of unspecified site
0.655 0.345 0.000
C62 Malignant neoplasm of testis
0.652 0.348 0.000
N73 Other female pelvic inflammatory diseases
0.652 0.348 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.650 0.350 0.000
N90.5 Atrophy of vulva
0.650 0.350 0.000
H73 Other disorders of tympanic membrane
0.649 0.351 0.000
H71 Cholesteatoma of middle ear
0.649 0.351 0.000
M40-M43 Deforming dorsopathies
0.648 0.352 0.000
D70 Agranulocytosis
0.645 0.355 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.645 0.355 0.000
M60-M63 Disorders of muscles
0.644 0.356 0.000
M00-M03 Infectious arthropathies
0.644 0.356 0.000
C77.4 Inguinal and lower limb lymph nodes
0.644 0.356 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.643 0.357 0.000
A80-A89 Viral infections of the central nervous system
0.642 0.358 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.642 0.358 0.000
M33 Dermatopolymyositis
0.642 0.358 0.000
M32 Systemic lupus erythematosus
0.642 0.358 0.000
M30 Polyarteritis nodosa and related conditions
0.642 0.358 0.000
M21 Other acquired deformities of limbs
0.642 0.358 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.641 0.359 0.000
M23.9 Internal derangement of knee, unspecified
0.638 0.361 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.638 0.361 0.000
M23.1 Discoid meniscus (congenital)
0.638 0.361 0.000
M23.0 Cystic meniscus
0.638 0.361 0.000
D06.9 Cervix, unspecified
0.638 0.362 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.638 0.362 0.000
Chapter V Mental and behavioural disorders
0.636 0.364 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.635 0.365 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.635 0.365 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.634 0.366 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.631 0.369 0.000
C79.6 Secondary malignant neoplasm of ovary
0.631 0.369 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.631 0.369 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.631 0.369 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.631 0.369 0.000
G93.3 Postviral fatigue syndrome
0.630 0.370 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.629 0.370 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.629 0.371 0.000
D72 Other disorders of white blood cells
0.628 0.372 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.627 0.373 0.000
G95 Other diseases of spinal cord
0.626 0.373 0.000
C77.1 Intrathoracic lymph nodes
0.626 0.374 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.626 0.374 0.000
H90-H95 Other disorders of ear
0.625 0.375 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.624 0.376 0.000
C60 Malignant neoplasm of penis
0.624 0.376 0.000
N89 Other noninflammatory disorders of vagina
0.624 0.376 0.000
N98 Complications associated with artificial fertilisation
0.623 0.377 0.000
N91 Absent, scanty and rare menstruation
0.623 0.377 0.000
N82 Fistulae involving female genital tract
0.623 0.377 0.000
N96 Habitual aborter
0.623 0.377 0.000
N13.3 Other and unspecified hydronephrosis
0.623 0.377 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.622 0.378 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.622 0.378 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.622 0.378 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.622 0.378 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.622 0.378 0.000
B99-B99 Other infectious diseases
0.621 0.378 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.621 0.378 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.621 0.378 0.000
B65-B83 Helminthiases
0.621 0.378 0.000
B50-B64 Protozoal diseases
0.621 0.378 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.621 0.378 0.000
B15-B19 Viral hepatitis
0.621 0.378 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.621 0.378 0.000
A75-A79 Rickettsioses
0.621 0.378 0.000
A70-A74 Other diseases caused by chlamydiae
0.621 0.378 0.000
A65-A69 Other spirochaetal diseases
0.621 0.378 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.621 0.378 0.000
A20-A28 Certain zoonotic bacterial diseases
0.621 0.378 0.000
A15-A19 Tuberculosis
0.621 0.378 0.000
N13.4 Hydroureter
0.620 0.379 0.000
N97 Female infertility
0.620 0.380 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.619 0.381 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.619 0.381 0.000
C53 Malignant neoplasm of cervix uteri
0.618 0.382 0.000
I21 Acute myocardial infarction
0.616 0.384 0.000
B37.9 Candidiasis, unspecified
0.614 0.386 0.000
N94.6 Dysmenorrhoea, unspecified
0.613 0.387 0.000
C77.3 Axillary and upper limb lymph nodes
0.612 0.388 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.611 0.389 0.000
I95.1 Orthostatic hypotension
0.610 0.390 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.609 0.391 0.000
N72 Inflammatory disease of cervix uteri
0.609 0.391 0.000
S00 Superficial injury of head
0.608 0.392 0.000
N10 Acute tubulo-interstitial nephritis
0.608 0.392 0.000
N83.0 Follicular cyst of ovary
0.607 0.393 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.606 0.394 0.000
H80-H83 Diseases of inner ear
0.604 0.396 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.604 0.396 0.000
C78.2 Secondary malignant neoplasm of pleura
0.603 0.397 0.000
N99-N99 Other disorders of the genitourinary system
0.602 0.398 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.602 0.398 0.000
N94.3 Premenstrual tension syndrome
0.600 0.400 0.000
I20 Angina pectoris
0.598 0.402 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.598 0.402 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.597 0.403 0.000
N15 Other renal tubulo-interstitial diseases
0.597 0.403 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.597 0.403 0.000
N11 Chronic tubulo-interstitial nephritis
0.597 0.403 0.000
D75 Other diseases of blood and blood-forming organs
0.597 0.403 0.000
G30-G32 Other degenerative diseases of the nervous system
0.597 0.403 0.000
N03 Chronic nephritic syndrome
0.596 0.404 0.000
C73 Malignant neoplasm of thyroid gland
0.596 0.404 0.000
H65.3 Chronic mucoid otitis media
0.595 0.405 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.595 0.405 0.000
H70 Mastoiditis and related conditions
0.595 0.405 0.000
H69 Other disorders of Eustachian tube
0.595 0.405 0.000
H68 Eustachian salpingitis and obstruction
0.595 0.405 0.000
H67 Otitis media in diseases classified elsewhere
0.595 0.405 0.000
N86 Erosion and ectropion of cervix uteri
0.594 0.406 0.000
D80-D89 Certain disorders involving the immune mechanism
0.594 0.406 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.594 0.406 0.000
N83.7 Haematoma of broad ligament
0.594 0.406 0.000
N83.6 Haematosalpinx
0.594 0.406 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.594 0.406 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.594 0.406 0.000
E10-E14 Diabetes mellitus
0.594 0.406 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.593 0.407 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.592 0.408 0.000
N18 Chronic renal failure
0.591 0.409 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.590 0.410 0.000
D73 Diseases of spleen
0.589 0.411 0.000
H61 Other disorders of external ear
0.589 0.411 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.588 0.412 0.000
B37.0 Candidal stomatitis
0.588 0.412 0.000
D09 Carcinoma in situ of other and unspecified sites
0.588 0.412 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.587 0.413 0.000
N85.7 Haematometra
0.586 0.414 0.000
N85.6 Intra-uterine synechiae
0.586 0.414 0.000
N85.5 Inversion of uterus
0.586 0.414 0.000
N85.3 Subinvolution of uterus
0.586 0.414 0.000
N85.1 Endometrial adenomatous hyperplasia
0.586 0.414 0.000
N90.6 Hypertrophy of vulva
0.584 0.416 0.000
N90.3 Dysplasia of vulva, unspecified
0.584 0.416 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.584 0.416 0.000
N90.1 Moderate vulvar dysplasia
0.584 0.416 0.000
N90.0 Mild vulvar dysplasia
0.584 0.416 0.000
C16 Malignant neoplasm of stomach
0.582 0.418 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.580 0.419 0.000
M23.37 Other meniscus derangements-Capsular lig
0.580 0.419 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.580 0.419 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.579 0.421 0.000
C51 Malignant neoplasm of vulva
0.579 0.421 0.000
C58 Malignant neoplasm of placenta
0.579 0.421 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.579 0.421 0.000
C52 Malignant neoplasm of vagina
0.579 0.421 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.578 0.421 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.578 0.421 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.578 0.422 0.000
M35 Other systemic involvement of connective tissue
0.574 0.426 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.574 0.426 0.000
I22 Subsequent myocardial infarction
0.573 0.427 0.000
H40-H42 Glaucoma
0.573 0.427 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.573 0.427 0.000
N60-N64 Disorders of breast
0.573 0.427 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.573 0.427 0.000
D04 Carcinoma in situ of skin
0.572 0.428 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.572 0.428 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.572 0.428 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.572 0.428 0.000
D03 Melanoma in situ
0.572 0.428 0.000
M20 Acquired deformities of fingers and toes
0.572 0.428 0.000
A48 Other bacterial diseases, not elsewhere classified
0.571 0.429 0.000
A44 Bartonellosis
0.571 0.429 0.000
A43 Nocardiosis
0.571 0.429 0.000
A42 Actinomycosis
0.571 0.429 0.000
A40 Streptococcal septicaemia
0.571 0.429 0.000
A39 Meningococcal infection
0.571 0.429 0.000
A37 Whooping cough
0.571 0.429 0.000
A36 Diphtheria
0.571 0.429 0.000
A32 Listeriosis
0.571 0.429 0.000
A31 Infection due to other mycobacteria
0.571 0.429 0.000
A30 Leprosy [Hansen's disease]
0.571 0.429 0.000
A46 Erysipelas
0.571 0.429 0.000
A38 Scarlet fever
0.571 0.429 0.000
A35 Other tetanus
0.571 0.429 0.000
A34 Obstetrical tetanus
0.571 0.429 0.000
A33 Tetanus neonatorum
0.571 0.429 0.000
H66.9 Otitis media, unspecified
0.570 0.430 0.000
N18.9 Chronic renal failure, unspecified
0.570 0.430 0.000
I25.2 Old myocardial infarction
0.570 0.430 0.000
H66.3 Other chronic suppurative otitis media
0.570 0.430 0.000
M23.49 Loose body in knee-Unspec lig/men
0.569 0.430 0.000
D37.4 Colon
0.569 0.431 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.568 0.432 0.000
N76 Other inflammation of vagina and vulva
0.568 0.432 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.568 0.432 0.000
N71 Inflammatory disease of uterus, except cervix
0.568 0.432 0.000
T31 Burns classified according to extent of body surface involved
0.567 0.433 0.000
E10 Insulin-dependent diabetes mellitus
0.566 0.434 0.000
M88 Paget's disease of bone [osteitis deformans]
0.565 0.435 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.565 0.435 0.000
H72 Perforation of tympanic membrane
0.564 0.435 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.564 0.436 0.000
D46 Myelodysplastic syndromes
0.563 0.437 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.563 0.437 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.563 0.437 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.563 0.437 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.563 0.437 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.563 0.437 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.563 0.437 0.000
H10-H13 Disorders of conjunctiva
0.563 0.437 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.562 0.438 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.560 0.440 0.000
N94.5 Secondary dysmenorrhoea
0.560 0.440 0.000
N94.4 Primary dysmenorrhoea
0.560 0.440 0.000
N94.2 Vaginismus
0.560 0.440 0.000
N94.0 Mittelschmerz
0.560 0.440 0.000
D55-D59 Haemolytic anaemias
0.560 0.440 0.000
N87.1 Moderate cervical dysplasia
0.559 0.440 0.000
G70-G73 Diseases of myoneural junction and muscle
0.559 0.441 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.559 0.441 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.559 0.441 0.000
I21.9 Acute myocardial infarction, unspecified
0.558 0.442 0.000
M25.54 Pain in joint (Hand)
0.557 0.442 0.000
M34.9 Systemic sclerosis, unspecified
0.557 0.443 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.557 0.443 0.000
G20-G26 Extrapyramidal and movement disorders
0.557 0.443 0.000
N75 Diseases of Bartholin's gland
0.555 0.445 0.000
M48 Other spondylopathies
0.555 0.445 0.000
S20-S29 Injuries to the thorax
0.555 0.445 0.000
B48 Other mycoses, not elsewhere classified
0.555 0.445 0.000
B47 Mycetoma
0.555 0.445 0.000
B46 Zygomycosis
0.555 0.445 0.000
B45 Cryptococcosis
0.555 0.445 0.000
B44 Aspergillosis
0.555 0.445 0.000
B43 Chromomycosis and phaeomycotic abscess
0.555 0.445 0.000
B42 Sporotrichosis
0.555 0.445 0.000
B41 Paracoccidioidomycosis
0.555 0.445 0.000
B40 Blastomycosis
0.555 0.445 0.000
B39 Histoplasmosis
0.555 0.445 0.000
B38 Coccidioidomycosis
0.555 0.445 0.000
B36 Other superficial mycoses
0.555 0.445 0.000
B35 Dermatophytosis
0.555 0.445 0.000
B49 Unspecified mycosis
0.555 0.445 0.000
I24 Other acute ischaemic heart diseases
0.555 0.445 0.000
A49.0 Staphylococcal infection, unspecified
0.554 0.446 0.000
N70.1 Chronic salpingitis and oophoritis
0.554 0.446 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.554 0.446 0.000
C77.0 Lymph nodes of head, face and neck
0.554 0.446 0.000
H55-H59 Other disorders of eye and adnexa
0.554 0.446 0.000
M80 Osteoporosis with pathological fracture
0.552 0.448 0.000
H65.4 Other chronic nonsuppurative otitis media
0.552 0.448 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.551 0.449 0.000
H43-H45 Disorders of vitreous body and globe
0.550 0.450 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.549 0.450 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.549 0.450 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.549 0.450 0.000
C21 Malignant neoplasm of anus and anal canal
0.549 0.450 0.000
C17 Malignant neoplasm of small intestine
0.549 0.450 0.000
C23 Malignant neoplasm of gallbladder
0.549 0.450 0.000
D45 Polycythaemia vera
0.549 0.451 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.549 0.451 0.000
M46 Other inflammatory spondylopathies
0.548 0.452 0.000
N02 Recurrent and persistent haematuria
0.547 0.453 0.000
D72.8 Other specified disorders of white blood cells
0.546 0.454 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.545 0.455 0.000
I00-I02 Acute rheumatic fever
0.545 0.455 0.000
C15 Malignant neoplasm of oesophagus
0.545 0.455 0.000
I95.2 Hypotension due to drugs
0.544 0.456 0.000
C78.0 Secondary malignant neoplasm of lung
0.544 0.456 0.000
B34 Viral infection of unspecified site
0.543 0.457 0.000
S00.0 Superficial injury of scalp
0.541 0.459 0.000
M25.53 Pain in joint (Forearm)
0.540 0.460 0.000
N90.7 Vulvar cyst
0.540 0.460 0.000
G95.2 Cord compression, unspecified
0.539 0.461 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.538 0.462 0.000
D47.2 Monoclonal gammopathy
0.538 0.462 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.537 0.463 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.537 0.463 0.000
G96 Other disorders of central nervous system
0.537 0.463 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.537 0.463 0.000
G91 Hydrocephalus
0.537 0.463 0.000
G90 Disorders of autonomic nervous system
0.537 0.463 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.537 0.463 0.000
G92 Toxic encephalopathy
0.537 0.463 0.000
B37.8 Candidiasis of other sites
0.537 0.463 0.000
T79-T79 Certain early complications of trauma
0.536 0.464 0.000
I20.0 Unstable angina
0.534 0.466 0.000
I25.1 Atherosclerotic heart disease
0.534 0.466 0.000
S01 Open wound of head
0.534 0.466 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.533 0.467 0.000
I99 Other and unspecified disorders of circulatory system
0.533 0.467 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.533 0.467 0.000
D74 Methaemoglobinaemia
0.533 0.467 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.533 0.467 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.533 0.467 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.532 0.468 0.000
N06 Isolated proteinuria with specified morphological lesion
0.532 0.468 0.000
N05 Unspecified nephritic syndrome
0.532 0.468 0.000
N04 Nephrotic syndrome
0.532 0.468 0.000
N01 Rapidly progressive nephritic syndrome
0.532 0.468 0.000
N00 Acute nephritic syndrome
0.532 0.468 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.531 0.469 0.000
D07.5 Prostate
0.531 0.469 0.000
M05-M14 Inflammatory polyarthropathies
0.531 0.469 0.000
N25-N29 Other disorders of kidney and ureter
0.530 0.470 0.000
H92 Otalgia and effusion of ear
0.529 0.471 0.000
H04 Disorders of lachrymal system
0.528 0.472 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.528 0.472 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.528 0.472 0.000
C74 Malignant neoplasm of adrenal gland
0.528 0.472 0.000
I23 Certain current complications following acute myocardial infarction
0.528 0.472 0.000
C54.9 Corpus uteri, unspecified
0.527 0.472 0.000
C54.8 Overlapping lesion of corpus uteri
0.527 0.472 0.000
C54.3 Fundus uteri
0.527 0.472 0.000
C54.2 Myometrium
0.527 0.472 0.000
C54.0 Isthmus uteri
0.527 0.472 0.000
D10-D36 Benign neoplasms
0.527 0.473 0.000
C71 Malignant neoplasm of brain
0.526 0.473 0.000
I95.8 Other hypotension
0.525 0.475 0.000
I95.0 Idiopathic hypotension
0.525 0.475 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.525 0.475 0.000
T31.0 Burns involving less than 10% of body surface
0.524 0.476 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.523 0.476 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.523 0.477 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.522 0.478 0.000
N73.6 Female pelvic peritoneal adhesions
0.521 0.479 0.000
M25.56 Pain in joint (Lower leg)
0.521 0.479 0.000
T66-T78 Other and unspecified effects of external causes
0.521 0.479 0.000
H73.8 Other specified disorders of tympanic membrane
0.520 0.479 0.000
M22.8 Other disorders of patella
0.519 0.481 0.000
M45 Ankylosing spondylitis
0.519 0.481 0.000
Chapter XX External causes of morbidity and mortality
0.518 0.482 0.000
M25.9 Joint disorder, unspecified
0.517 0.482 0.000
M25.8 Other specified joint disorders
0.517 0.482 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.517 0.482 0.000
M25.3 Other instability of joint
0.517 0.482 0.000
M25.2 Flail joint
0.517 0.482 0.000
M25.1 Fistula of joint
0.517 0.482 0.000
M25.0 Haemarthrosis
0.517 0.482 0.000
M85 Other disorders of bone density and structure
0.517 0.483 0.000
M67 Other disorders of synovium and tendon
0.517 0.483 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.516 0.484 0.000
M50 Cervical disk disorders
0.516 0.484 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.514 0.486 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.514 0.486 0.000
C25 Malignant neoplasm of pancreas
0.513 0.486 0.000
A41.8 Other specified septicaemia
0.513 0.487 0.000
A41.4 Septicaemia due to anaerobes
0.513 0.487 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.513 0.487 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.513 0.487 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.513 0.487 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.513 0.487 0.000
S00.9 Superficial injury of head, part unspecified
0.512 0.488 0.000
Q80-Q89 Other congenital malformations
0.512 0.488 0.000
C80.9 Malignant neoplasm, unspecified
0.512 0.488 0.000
N88.2 Stricture and stenosis of cervix uteri
0.512 0.488 0.000
M49 Spondylopathies in diseases classified elsewhere
0.509 0.490 0.000
N80 Endometriosis
0.509 0.491 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.509 0.491 0.000
T33-T35 Frostbite
0.508 0.492 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.508 0.492 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.508 0.492 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.508 0.492 0.000
T00-T07 Injuries involving multiple body regions
0.508 0.492 0.000
S10-S19 Injuries to the neck
0.508 0.492 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.508 0.492 0.000
B37.7 Candidal septicaemia
0.507 0.493 0.000
B37.6 Candidal endocarditis
0.507 0.493 0.000
B37.5 Candidal meningitis
0.507 0.493 0.000
B37.4 Candidiasis of other urogenital sites
0.507 0.493 0.000
B37.3 Candidiasis of vulva and vagina
0.507 0.493 0.000
B37.2 Candidiasis of skin and nail
0.507 0.493 0.000
B37.1 Pulmonary candidiasis
0.507 0.493 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.507 0.493 0.000
C66 Malignant neoplasm of ureter
0.507 0.493 0.000
C65 Malignant neoplasm of renal pelvis
0.507 0.493 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.507 0.493 0.000
H60 Otitis externa
0.507 0.493 0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.506 0.494 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.506 0.494 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.506 0.494 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.506 0.494 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.506 0.494 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.506 0.494 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.506 0.494 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.506 0.494 0.000
S09 Other and unspecified injuries of head
0.506 0.494 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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