TreeWAS – Variant ID: rs1144403

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.019	0.981	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.017	0.983	0.000
S63.0 Dislocation of wrist	0.016	0.983	0.000
S63.6 Sprain and strain of finger(s)	0.015	0.985	0.000
S63.2 Multiple dislocations of fingers	0.013	0.987	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.013	0.987	0.000
S63.1 Dislocation finger	0.012	0.988	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.012	0.988	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.988	0.012
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.989	0.011
Z22 Carrier of infectious disease	0.000	0.989	0.011
S63.5 Sprain and strain of wrist	0.010	0.990	0.000
Z22.5 Carrier of viral hepatitis	0.000	0.990	0.010
T46.1 Calcium-channel blockers	0.000	0.991	0.009
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.991	0.009
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.009	0.991	0.000
Z22.8 Carrier of other infectious diseases	0.000	0.991	0.009
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.991	0.009
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.991	0.009
D47.1 Chronic myeloproliferative disease	0.009	0.991	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.992	0.008
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.992	0.008
Z22.9 Carrier of infectious disease, unspecified	0.000	0.992	0.008
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.992	0.008
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.992	0.008
Z22.2 Carrier of diphtheria	0.000	0.992	0.008
Z22.0 Carrier of typhoid	0.000	0.992	0.008
T42.4 Benzodiazepines	0.000	0.992	0.008
T42.1 Iminostilbenes	0.000	0.992	0.008
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.993	0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.993	0.007
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.993	0.007
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.993	0.007
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.993	0.007
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.993	0.007
T46.7 Peripheral vasodilators	0.000	0.993	0.007
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.993	0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.993	0.007
F10.2 Dependence syndrome	0.007	0.993	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.993	0.007
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.993	0.006
S69.9 Unspecified injury of wrist and hand	0.007	0.993	0.000
T42.0 Hydantoin derivatives	0.000	0.993	0.006
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.994	0.006
T42.2 Succinimides and oxazolidinediones	0.000	0.994	0.006
S68 Traumatic amputation of wrist and hand	0.006	0.994	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.994	0.006
S69 Other and unspecified injuries of wrist and hand	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.994	0.006
C83.3 Large cell (diffuse)	0.000	0.994	0.006
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.994	0.006
T42.3 Barbiturates	0.000	0.994	0.006
T38.1 Thyroid hormones and substitutes	0.000	0.994	0.006
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.994	0.006
K75.9 Inflammatory liver disease, unspecified	0.006	0.994	0.000
S60-S69 Injuries to the wrist and hand	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.994	0.006
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.994	0.006
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.994	0.006
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.994	0.006
N75.1 Abscess of Bartholin's gland	0.006	0.994	0.000
K75.0 Abscess of liver	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.994	0.005
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.994	0.005
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.995	0.005
T78 Adverse effects, not elsewhere classified	0.000	0.995	0.005
Z83.7 Family history of diseases of the digestive system	0.000	0.995	0.005
T78.8 Other adverse effects, not elsewhere classified	0.000	0.995	0.005
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.995	0.005
Z63.8 Other specified problems related to primary support group	0.000	0.995	0.005
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.995	0.005
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.995	0.005
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.995	0.005
T44.0 Anticholinesterase agents	0.000	0.995	0.005
Z63 Other problems related to primary support group, including family circumstances	0.000	0.995	0.005
T78.3 Angioneurotic oedema	0.000	0.995	0.005
T78.4 Allergy, unspecified	0.000	0.995	0.005
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.995	0.005
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.995	0.005
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.995	0.005
K75 Other inflammatory liver diseases	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.995	0.005
T38.7 Androgens and anabolic congeners	0.000	0.995	0.005
T38.5 Other oestrogens and progestogens	0.000	0.995	0.005
T38.4 Oral contraceptives	0.000	0.995	0.005
T38.2 Antithyroid drugs	0.000	0.995	0.005
T38.0 Glucocorticoids and synthetic analogues	0.000	0.995	0.005
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.995	0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.995	0.005
Z63.0 Problems in relationship with spouse or partner	0.000	0.995	0.005
Z63.4 Disappearance and death of family member	0.000	0.995	0.005
S69.7 Multiple injuries of wrist and hand	0.005	0.995	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.995	0.005
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.005	0.995	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.005	0.995	0.000
S68.4 Traumatic amputation of hand at wrist level	0.005	0.995	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.005	0.995	0.000
T47.4 Other laxatives	0.000	0.995	0.005
T47.2 Stimulant laxatives	0.000	0.995	0.005
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.995	0.005
Z28 Immunisation not carried out	0.000	0.995	0.005
Z27 Need for immunisation against combinations of infectious diseases	0.000	0.995	0.005
Z25 Need for immunisation against other single viral diseases	0.000	0.995	0.005
Z23 Need for immunisation against single bacterial diseases	0.000	0.995	0.005
S67 Crushing injury of wrist and hand	0.005	0.995	0.000
Z24 Need for immunisation against certain single viral diseases	0.000	0.995	0.005
Z20 Contact with and exposure to communicable diseases	0.000	0.995	0.005
S68.0 Traumatic amputation of thumb (complete)(partial)	0.005	0.995	0.000
Z26 Need for immunisation against other single infectious diseases	0.000	0.995	0.005
K75.3 Granulomatous hepatitis, not elsewhere classified	0.005	0.995	0.000
S65 Injury of blood vessels at wrist and hand level	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.000	0.995	0.004
Z63.7 Other stressful life events affecting family and household	0.000	0.995	0.005
S61.9 Open wound of wrist and hand, part unspecified	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.995	0.004
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.995	0.004
T47.7 Emetics	0.000	0.995	0.004
T47.5 Digestants	0.000	0.995	0.004
T47.3 Saline and osmotic laxatives	0.000	0.995	0.004
S69.8 Other specified injuries of wrist and hand	0.004	0.995	0.000
S62 Fracture at wrist and hand level	0.005	0.995	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.004	0.995	0.000
Z63.5 Disruption of family by separation and divorce	0.000	0.996	0.004
T47.0 Histamine H(2)-receptor antagonists	0.000	0.996	0.004
S65.5 Injury of blood vessel(s) of other finger	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.996	0.004
T48.4 Expectorants	0.000	0.996	0.004
T48.3 Antitussives	0.000	0.996	0.004
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.996	0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.996	0.004
T48.0 Oxytocic drugs	0.000	0.996	0.004
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.000	0.996	0.004
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
T78.9 Adverse effect, unspecified	0.000	0.996	0.004
S67.0 Crushing injury of thumb and other finger(s)	0.004	0.996	0.000
S62.3 Fracture of other metacarpal bone	0.004	0.996	0.000
K75.8 Other specified inflammatory liver diseases	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
C83.7 Burkitt's tumour	0.000	0.996	0.004
Z63.9 Problem related to primary support group, unspecified	0.000	0.996	0.004
Z63.3 Absence of family member	0.000	0.996	0.004
Z63.2 Inadequate family support	0.000	0.996	0.004
Z63.1 Problems in relationship with parents and in-laws	0.000	0.996	0.004
S62.30 Fracture of other metacarpal bone (closed)	0.004	0.996	0.000
T41.5 Therapeutic gases	0.000	0.996	0.004
T41.4 Anaesthetic, unspecified	0.000	0.996	0.004
T41.3 Local anaesthetics	0.000	0.996	0.004
T41.2 Other and unspecified general anaesthetics	0.000	0.996	0.004
T41.1 Intravenous anaesthetics	0.000	0.996	0.004
T41.0 Inhaled anaesthetics	0.000	0.996	0.004
K75.2 Nonspecific reactive hepatitis	0.004	0.996	0.000
K75.1 Phlebitis of portal vein	0.004	0.996	0.000
Z63.6 Dependent relative needing care at home	0.000	0.996	0.004
T49.9 Topical agent, unspecified	0.000	0.996	0.004
T49.8 Other topical agents	0.000	0.996	0.004
T49.7 Dental drugs, topically applied	0.000	0.996	0.004
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.004
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.004
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.004
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.004
T49.2 Local astringents and local detergents	0.000	0.996	0.004
T49.1 Antipruritics	0.000	0.996	0.004
S62.8 Fracture of other and unspecified parts of wrist and hand	0.004	0.996	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.000	0.996	0.004
Z23.8 Need for immunisation against other single bacterial diseases	0.000	0.996	0.003
Z23.7 Need for immunisation against pertussis alone	0.000	0.996	0.003
Z23.6 Need for immunisation against diphtheria alone	0.000	0.996	0.003
Z23.5 Need for immunisation against tetanus alone	0.000	0.996	0.003
Z23.4 Need for immunisation against tularaemia	0.000	0.996	0.003
Z23.3 Need for immunisation against plague	0.000	0.996	0.003
Z23.2 Need for immunisation against tuberculosis [BCG]	0.000	0.996	0.003
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.000	0.996	0.003
Z23.0 Need for immunisation against cholera alone	0.000	0.996	0.003
Z25.8 Need for immunisation against other specified single viral diseases	0.000	0.996	0.003
Z25.1 Need for immunisation against influenza	0.000	0.996	0.003
Z25.0 Need for immunisation against mumps alone	0.000	0.996	0.003
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.000	0.996	0.003
Z27.8 Need for immunisation against other combinations of infectious diseases	0.000	0.996	0.003
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.000	0.996	0.003
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.000	0.996	0.003
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.000	0.996	0.003
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.000	0.996	0.003
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.000	0.996	0.003
Z28.9 Immunisation not carried out for unspecified reason	0.000	0.996	0.003
Z28.8 Immunisation not carried out for other reasons	0.000	0.996	0.003
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.000	0.996	0.003
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.000	0.996	0.003
Z28.0 Immunisation not carried out because of contraindication	0.000	0.996	0.003
S65.0 Injury of ulnar artery at wrist and hand level	0.004	0.996	0.000
C83.0 Small cell (diffuse)	0.000	0.996	0.004
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.000	0.996	0.003
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.000	0.996	0.003
Z20.5 Contact with and exposure to viral hepatitis	0.000	0.996	0.003
Z20.4 Contact with and exposure to rubella	0.000	0.996	0.003
Z20.3 Contact with and exposure to rabies	0.000	0.996	0.003
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.000	0.996	0.003
Z20.0 Contact with and exposure to intestinal infectious diseases	0.000	0.996	0.003
Z24.6 Need for immunisation against viral hepatitis	0.000	0.996	0.003
Z24.4 Need for immunisation against measles alone	0.000	0.996	0.003
Z24.3 Need for immunisation against yellow fever	0.000	0.996	0.003
Z24.2 Need for immunisation against rabies	0.000	0.996	0.003
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.000	0.996	0.003
Z24.0 Need for immunisation against poliomyelitis	0.000	0.996	0.003
Z26.8 Need for immunisation against other specified single infectious diseases	0.000	0.996	0.003
Z26.0 Need for immunisation against leishmaniasis	0.000	0.996	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.996	0.004
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.003	0.996	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.003	0.996	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.003	0.996	0.000
S65.3 Injury of deep palmar arch	0.003	0.996	0.000
S65.2 Injury of superficial palmar arch	0.003	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.003
S62.6 Fracture of other finger	0.004	0.996	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.004	0.996	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.996	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
Z20.1 Contact with and exposure to tuberculosis	0.000	0.996	0.003
Z24.5 Need for immunisation against rubella alone	0.000	0.996	0.003
Z20.9 Contact with and exposure to unspecified communicable disease	0.000	0.996	0.003
Z26.9 Need for immunisation against unspecified infectious disease	0.000	0.996	0.003
K74.3 Primary biliary cirrhosis	0.004	0.996	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.996	0.003
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
S65.4 Injury of blood vessel(s) of thumb	0.003	0.997	0.000
T66-T78 Other and unspecified effects of external causes	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.003	0.997	0.000
R07.1 Chest pain on breathing	0.000	0.997	0.003
N75 Diseases of Bartholin's gland	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.000	0.997	0.003
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
S62.31 Fracture of other metacarpal bone (open)	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.997	0.003
K14.9 Disease of tongue, unspecified	0.003	0.997	0.000
S62.2 Fracture of first metacarpal bone	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.003	0.997	0.000
T75 Effects of other external causes	0.000	0.997	0.003
C34.2 Middle lobe, bronchus or lung	0.000	0.997	0.003
Q43.0 Meckel's diverticulum	0.000	0.997	0.003
S62.5 Fracture of thumb	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.000	0.997	0.003
F60.9 Personality disorder, unspecified	0.000	0.997	0.003
F60 Specific personality disorders	0.000	0.997	0.003
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
S64.0 Injury of ulnar nerve at wrist and hand level	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
T75.1 Drowning and nonfatal submersion	0.000	0.997	0.003
L43.8 Other lichen planus	0.003	0.997	0.000
S64 Injury of nerves at wrist and hand level	0.003	0.997	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.003	0.997	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.003	0.997	0.000
J34.2 Deviated nasal septum	0.000	0.997	0.003
S65.1 Injury of radial artery at wrist and hand level	0.002	0.997	0.000
K74.0 Hepatic fibrosis	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
N75.8 Other diseases of Bartholin's gland	0.003	0.997	0.000
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
T71 Asphyxiation	0.000	0.997	0.003
F60.0 Paranoid personality disorder	0.000	0.997	0.003
T40.2 Other opioids	0.000	0.997	0.003
J80 Adult respiratory distress syndrome	0.000	0.997	0.003
T74 Maltreatment syndromes	0.000	0.997	0.003
T73 Effects of other deprivation	0.000	0.997	0.003
T69 Other effects of reduced temperature	0.000	0.997	0.003
T67 Effects of heat and light	0.000	0.997	0.003
Q43 Other congenital malformations of intestine	0.000	0.997	0.003
T70 Effects of air pressure and water pressure	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.002	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.002	0.997	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.002	0.997	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.997	0.003
Q43.3 Congenital malformations of intestinal fixation	0.000	0.997	0.003
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.002	0.997	0.000
Z64.0 Problems related to unwanted pregnancy	0.000	0.997	0.003
I49.9 Cardiac arrhythmia, unspecified	0.003	0.997	0.000
T40.1 Heroin	0.000	0.997	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.002
T40.4 Other synthetic narcotics	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.000	0.998	0.002
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
S62.21 Fracture of first metacarpal bone (open)	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
C48.0 Retroperitoneum	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
K70-K77 Diseases of liver	0.002	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.002	0.998	0.000
T75.8 Other specified effects of external causes	0.000	0.998	0.002
T75.3 Motion sickness	0.000	0.998	0.002
T75.2 Effects of vibration	0.000	0.998	0.002
T75.0 Effects of lightning	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.000	0.998	0.002
F64.0 Transsexualism	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.000	0.998	0.002
I30.1 Infective pericarditis	0.002	0.998	0.000
T40.5 Cocaine	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
F60.4 Histrionic personality disorder	0.000	0.998	0.002
F60.1 Schizoid personality disorder	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
Z64 Problems related to certain psychosocial circumstances	0.000	0.998	0.002
T75.4 Effects of electric current	0.000	0.998	0.002
Z61 Problems related to negative life events in childhood	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.002	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.000	0.998	0.002
Q43.1 Hirschsprung's disease	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
F64 Gender identity disorders	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.002
T67.8 Other effects of heat and light	0.000	0.998	0.002
T67.7 Heat oedema	0.000	0.998	0.002
T67.6 Heat fatigue, transient	0.000	0.998	0.002
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.002
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.002
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.002
T67.2 Heat cramp	0.000	0.998	0.002
T67.1 Heat syncope	0.000	0.998	0.002
T67.0 Heatstroke and sunstroke	0.000	0.998	0.002
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.002
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.002
T69.1 Chilblains	0.000	0.998	0.002
T69.0 Immersion hand and foot	0.000	0.998	0.002
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.998	0.002
T70.8 Other effects of air pressure and water pressure	0.000	0.998	0.002
T70.4 Effects of high-pressure fluids	0.000	0.998	0.002
T70.2 Other and unspecified effects of high altitude	0.000	0.998	0.002
T70.1 Sinus barotrauma	0.000	0.998	0.002
T70.0 Otitic barotrauma	0.000	0.998	0.002
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.002
T73.8 Other effects of deprivation	0.000	0.998	0.002
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.002
T73.2 Exhaustion due to exposure	0.000	0.998	0.002
T73.1 Effects of thirst	0.000	0.998	0.002
T73.0 Effects of hunger	0.000	0.998	0.002
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.002
T74.8 Other maltreatment syndromes	0.000	0.998	0.002
T74.3 Psychological abuse	0.000	0.998	0.002
T74.2 Sexual abuse	0.000	0.998	0.002
T74.1 Physical abuse	0.000	0.998	0.002
T74.0 Neglect or abandonment	0.000	0.998	0.002
Q43.7 Persistent cloaca	0.000	0.998	0.002
Q43.6 Congenital fistula of rectum and anus	0.000	0.998	0.002
Q43.5 Ectopic anus	0.000	0.998	0.002
Q43.4 Duplication of intestine	0.000	0.998	0.002
Q43.2 Other congenital functional disorders of colon	0.000	0.998	0.002
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.998	0.002
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.002
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.998	0.002
K14.8 Other diseases of tongue	0.002	0.998	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.998	0.002
K77 Liver disorders in diseases classified elsewhere	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.002
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
S61 Open wound of wrist and hand	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.000	0.998	0.002
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
T45.5 Anticoagulants	0.000	0.998	0.002
Q43.9 Congenital malformation of intestine, unspecified	0.000	0.998	0.002
F60.6 Anxious [avoidant] personality disorder	0.000	0.998	0.002
H47.2 Optic atrophy	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
Z61.8 Other negative life events in childhood	0.000	0.998	0.002
Z64.4 Discord with counsellors	0.000	0.998	0.002
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.1 Problems related to multiparity	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.002
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.002
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.002
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.002
Z61.1 Removal from home in childhood	0.000	0.998	0.002
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
Z56 Problems related to employment and unemployment	0.000	0.998	0.002
S64.1 Injury of median nerve at wrist and hand level	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
F64.9 Gender identity disorder, unspecified	0.000	0.998	0.002
F64.8 Other gender identity disorders	0.000	0.998	0.002
F64.2 Gender identity disorder of childhood	0.000	0.998	0.002
F64.1 Dual-role transvestism	0.000	0.998	0.002
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.002	0.998	0.000
Z56.0 Unemployment, unspecified	0.000	0.998	0.002
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.002	0.998	0.000
F61 Mixed and other personality disorders	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.002
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.998	0.002
K73 Chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.000	0.998	0.002
Z55 Problems related to education and literacy	0.000	0.998	0.002
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.002	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.002	0.998	0.000
C48.2 Peritoneum, unspecified	0.002	0.998	0.000
C48.1 Specified parts of peritoneum	0.002	0.998	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S60.1 Contusion of finger(s) with damage to nail	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.002	0.998	0.000
H47.6 Disorders of visual cortex	0.002	0.998	0.000
H47.4 Disorders of optic chiasm	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.998	0.001
F68 Other disorders of adult personality and behaviour	0.000	0.998	0.002
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.998	0.002
F65 Disorders of sexual preference	0.000	0.998	0.002
F63 Habit and impulse disorders	0.000	0.998	0.002
K71 Toxic liver disease	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.002
Z58 Problems related to physical environment	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations