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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114592654
log Bayes Factor = 15.287
Chromosome 2   position 12,614,388  (GRCh37) Explore rs114592654 on Ensembl!
Variant rs114592654 is part of Cluster X0181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
1.000 0.000 0.000
N39 Other disorders of urinary system
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.995 0.005 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
N39.0 Urinary tract infection, site not specified
0.987 0.013 0.000
M70-M79 Other soft tissue disorders
0.986 0.014 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.983 0.017 0.000
Chapter IX Diseases of the circulatory system
0.982 0.018 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.980 0.020 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.979 0.021 0.000
I60-I69 Cerebrovascular diseases
0.979 0.021 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.977 0.023 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.969 0.031 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.961 0.039 0.000
Chapter V Mental and behavioural disorders
0.959 0.041 0.000
G90-G99 Other disorders of the nervous system
0.955 0.045 0.000
M79.6 Pain in limb
0.955 0.045 0.000
N17-N19 Renal failure
0.954 0.046 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.953 0.047 0.000
L50-L54 Urticaria and erythema
0.949 0.051 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.947 0.053 0.000
M79.66 Pain in limb (Lower leg)
0.942 0.058 0.000
M05-M14 Inflammatory polyarthropathies
0.936 0.064 0.000
M86-M90 Other osteopathies
0.931 0.069 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.928 0.072 0.000
N39.8 Other specified disorders of urinary system
0.923 0.077 0.000
L20-L30 Dermatitis and eczema
0.922 0.078 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.917 0.083 0.000
L53 Other erythematous conditions
0.916 0.084 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.913 0.087 0.000
I67 Other cerebrovascular diseases
0.912 0.088 0.000
A30-A49 Other bacterial diseases
0.909 0.091 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.904 0.096 0.000
N19 Unspecified renal failure
0.900 0.100 0.000
M45-M49 Spondylopathies
0.895 0.105 0.000
E70-E90 Metabolic disorders
0.892 0.108 0.000
L53.9 Erythematous condition, unspecified
0.892 0.108 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.892 0.108 0.000
N17 Acute renal failure
0.884 0.116 0.000
N36 Other disorders of urethra
0.883 0.117 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.880 0.120 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.879 0.121 0.000
N99-N99 Other disorders of the genitourinary system
0.873 0.127 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.871 0.129 0.000
O80-O84 Delivery
0.870 0.130 0.000
I67.8 Other specified cerebrovascular diseases
0.865 0.135 0.000
O80 Single spontaneous delivery
0.864 0.136 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.864 0.136 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.860 0.140 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.859 0.141 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.859 0.141 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.855 0.145 0.000
M80-M85 Disorders of bone density and structure
0.854 0.146 0.000
N60-N64 Disorders of breast
0.854 0.146 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.853 0.147 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.853 0.147 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.851 0.149 0.000
M47 Spondylosis
0.851 0.149 0.000
V80-V89 Other land transport accidents
0.848 0.152 0.000
O80.0 Spontaneous vertex delivery
0.848 0.152 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.846 0.154 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.846 0.154 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.846 0.154 0.000
F41 Other anxiety disorders
0.843 0.157 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.839 0.161 0.000
I05-I09 Chronic rheumatic heart diseases
0.838 0.162 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.838 0.162 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.836 0.164 0.000
N35 Urethral stricture
0.835 0.165 0.000
G93 Other disorders of brain
0.834 0.166 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.829 0.171 0.000
M13 Other arthritis
0.829 0.171 0.000
Y52 Agents primarily affecting the cardiovascular system
0.827 0.173 0.000
G20-G26 Extrapyramidal and movement disorders
0.827 0.173 0.000
L29 Pruritus
0.826 0.174 0.000
M10 Gout
0.825 0.175 0.000
Chapter XI Diseases of the digestive system
0.825 0.175 0.000
L03 Cellulitis
0.823 0.177 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.823 0.177 0.000
N00-N08 Glomerular diseases
0.823 0.177 0.000
I63 Cerebral infarction
0.822 0.178 0.000
M79.1 Myalgia
0.819 0.181 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.819 0.181 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.815 0.185 0.000
N17.9 Acute renal failure, unspecified
0.811 0.189 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.811 0.189 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.810 0.190 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.810 0.190 0.000
N30 Cystitis
0.808 0.192 0.000
T81 Complications of procedures, not elsewhere classified
0.804 0.196 0.000
Y40 Systemic antibiotics
0.803 0.197 0.000
Chapter VII Diseases of the eye and adnexa
0.800 0.200 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.800 0.200 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.800 0.200 0.000
M47.8 Other spondylosis
0.799 0.201 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.799 0.201 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.798 0.202 0.000
N39.9 Disorder of urinary system, unspecified
0.798 0.202 0.000
N36.8 Other specified disorders of urethra
0.797 0.203 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.794 0.206 0.000
T92 Sequelae of injuries of upper limb
0.793 0.207 0.000
O80.9 Single spontaneous delivery, unspecified
0.793 0.207 0.000
M79.8 Other specified soft tissue disorders
0.791 0.208 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.789 0.211 0.000
M77 Other enthesopathies
0.789 0.211 0.000
K65-K67 Diseases of peritoneum
0.788 0.212 0.000
A49 Bacterial infection of unspecified site
0.788 0.212 0.000
M86 Osteomyelitis
0.786 0.214 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.785 0.215 0.000
W50-W64 Exposure to animate mechanical forces
0.785 0.215 0.000
E83 Disorders of mineral metabolism
0.784 0.216 0.000
B15-B19 Viral hepatitis
0.784 0.216 0.000
L27 Dermatitis due to substances taken internally
0.783 0.217 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.782 0.218 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.775 0.225 0.000
E88 Other metabolic disorders
0.775 0.225 0.000
M20-M25 Other joint disorders
0.775 0.225 0.000
I61 Intracerebral haemorrhage
0.775 0.225 0.000
F41.2 Mixed anxiety and depressive disorder
0.775 0.225 0.000
M47.82 Other spondylosis (Cervical region)
0.774 0.226 0.000
L03.0 Cellulitis of finger and toe
0.773 0.227 0.000
I69 Sequelae of cerebrovascular disease
0.773 0.227 0.000
I62 Other nontraumatic intracranial haemorrhage
0.772 0.227 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.772 0.228 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.772 0.228 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.771 0.229 0.000
Chapter XXII Codes for special purposes
0.771 0.229 0.000
N39.3 Stress incontinence
0.769 0.231 0.000
K66 Other disorders of peritoneum
0.769 0.231 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.769 0.231 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.768 0.232 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.768 0.232 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.767 0.233 0.000
F05.9 Delirium, unspecified
0.767 0.233 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.765 0.235 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.762 0.237 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.762 0.238 0.000
M87 Osteonecrosis
0.761 0.239 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.759 0.241 0.000
M89 Other disorders of bone
0.758 0.242 0.000
K85 Acute pancreatitis
0.757 0.243 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.756 0.244 0.000
T90 Sequelae of injuries of head
0.756 0.244 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.755 0.245 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.755 0.245 0.000
M79.0 Rheumatism, unspecified
0.754 0.246 0.000
F40 Phobic anxiety disorders
0.752 0.248 0.000
T66-T78 Other and unspecified effects of external causes
0.750 0.250 0.000
Y57 Other and unspecified drugs and medicaments
0.750 0.250 0.000
M47.9 Spondylosis, unspecified
0.750 0.250 0.000
E83.1 Disorders of iron metabolism
0.750 0.250 0.000
Y49.5 Other antipsychotics and neuroleptics
0.750 0.250 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.749 0.251 0.000
M79.5 Residual foreign body in soft tissue
0.749 0.251 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.747 0.253 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.747 0.253 0.000
M10.9 Gout, unspecified
0.746 0.254 0.000
I95 Hypotension
0.746 0.254 0.000
E87.2 Acidosis
0.744 0.256 0.000
N32 Other disorders of bladder
0.742 0.258 0.000
K66.0 Peritoneal adhesions
0.742 0.258 0.000
G40-G47 Episodic and paroxysmal disorders
0.740 0.260 0.000
H04 Disorders of lachrymal system
0.740 0.260 0.000
T87 Complications peculiar to reattachment and amputation
0.738 0.262 0.000
F45 Somatoform disorders
0.738 0.262 0.000
T93 Sequelae of injuries of lower limb
0.738 0.262 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.736 0.264 0.000
N60 Benign mammary dysplasia
0.735 0.265 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.735 0.265 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.734 0.266 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.734 0.266 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
A40 Streptococcal septicaemia
0.733 0.267 0.000
E86 Volume depletion
0.731 0.269 0.000
L05 Pilonidal cyst
0.730 0.270 0.000
G90 Disorders of autonomic nervous system
0.730 0.270 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.729 0.271 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.727 0.272 0.000
L29.2 Pruritus vulvae
0.727 0.273 0.000
M13.9 Arthritis, unspecified
0.727 0.273 0.000
N64 Other disorders of breast
0.724 0.276 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.724 0.276 0.000
F30-F39 Mood [affective] disorders
0.724 0.276 0.000
M88 Paget's disease of bone [osteitis deformans]
0.723 0.276 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.723 0.277 0.000
L08 Other local infections of skin and subcutaneous tissue
0.722 0.277 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.722 0.278 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.721 0.279 0.000
M14 Arthropathies in other diseases classified elsewhere
0.719 0.281 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.718 0.281 0.000
B35-B49 Mycoses
0.718 0.282 0.000
Y42.5 Other oestrogens and progestogens
0.718 0.282 0.000
M00-M03 Infectious arthropathies
0.717 0.282 0.000
M15-M19 Arthrosis
0.718 0.282 0.000
N35.9 Urethral stricture, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.717 0.283 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.717 0.283 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.714 0.286 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.714 0.286 0.000
N39.2 Orthostatic proteinuria, unspecified
0.714 0.286 0.000
N39.1 Persistent proteinuria, unspecified
0.714 0.286 0.000
L10-L14 Bullous disorders
0.713 0.287 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.713 0.287 0.000
Q80-Q89 Other congenital malformations
0.712 0.288 0.000
G25 Other extrapyramidal and movement disorders
0.712 0.288 0.000
N25-N29 Other disorders of kidney and ureter
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
N17.0 Acute renal failure with tubular necrosis
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
A41 Other septicaemia
0.709 0.291 0.000
I67.1 Cerebral aneurysm, nonruptured
0.708 0.292 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.708 0.292 0.000
M76 Enthesopathies of lower limb, excluding foot
0.707 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.707 0.293 0.000
M91-M94 Chondropathies
0.707 0.293 0.000
M05 Seropositive rheumatoid arthritis
0.706 0.294 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.706 0.294 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.706 0.294 0.000
I08 Multiple valve diseases
0.705 0.295 0.000
E87.0 Hyperosmolality and hypernatraemia
0.705 0.295 0.000
L40-L45 Papulosquamous disorders
0.704 0.296 0.000
L85 Other epidermal thickening
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.704 0.296 0.000
M79.7 Fibromyalgia
0.703 0.297 0.000
M71 Other bursopathies
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.703 0.297 0.000
Y58 Bacterial vaccines
0.703 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.703 0.297 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.703 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.703 0.297 0.000
Y48 Anaesthetics and therapeutic gases
0.703 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.703 0.297 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.703 0.297 0.000
G93.0 Cerebral cysts
0.703 0.297 0.000
M79.9 Soft tissue disorder, unspecified
0.702 0.298 0.000
M79.3 Panniculitis, unspecified
0.702 0.298 0.000
M79.2 Neuralgia and neuritis, unspecified
0.702 0.298 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.702 0.298 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
H04.2 Epiphora
0.702 0.298 0.000
K85.9 Acute pancreatitis, unspecified
0.701 0.299 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.700 0.300 0.000
G91 Hydrocephalus
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.300 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.699 0.301 0.000
L29.9 Pruritus, unspecified
0.699 0.301 0.000
G35 Multiple sclerosis
0.699 0.301 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.697 0.303 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
R14 Flatulence and related conditions
0.696 0.304 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.695 0.305 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.695 0.305 0.000
F01 Vascular dementia
0.695 0.305 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.695 0.305 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.694 0.305 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.691 0.309 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.691 0.309 0.000
A49.8 Other bacterial infections of unspecified site
0.691 0.309 0.000
T33-T35 Frostbite
0.689 0.311 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.689 0.311 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.689 0.311 0.000
T00-T07 Injuries involving multiple body regions
0.689 0.311 0.000
S10-S19 Injuries to the neck
0.689 0.311 0.000
K81 Cholecystitis
0.689 0.311 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.688 0.312 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.688 0.312 0.000
F70-F79 Mental retardation
0.688 0.312 0.000
F60-F69 Disorders of adult personality and behaviour
0.688 0.312 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.687 0.313 0.000
L03.2 Cellulitis of face
0.687 0.313 0.000
M79.60 Pain in limb (Multiple sites)
0.687 0.313 0.000
S60-S69 Injuries to the wrist and hand
0.687 0.313 0.000
I67.2 Cerebral atherosclerosis
0.686 0.314 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.686 0.314 0.000
K40-K46 Hernia
0.686 0.314 0.000
M85 Other disorders of bone density and structure
0.685 0.315 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.685 0.315 0.000
G96 Other disorders of central nervous system
0.684 0.315 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.315 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.315 0.000
G92 Toxic encephalopathy
0.684 0.315 0.000
M79.68 Pain in limb (Other)
0.684 0.315 0.000
M79.61 Pain in limb (Shoulder region)
0.684 0.315 0.000
A00-A09 Intestinal infectious diseases
0.684 0.316 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.684 0.316 0.000
M46 Other inflammatory spondylopathies
0.683 0.317 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.683 0.317 0.000
T82.1 Mechanical complication of cardiac electronic device
0.683 0.317 0.000
F80-F89 Disorders of psychological development
0.682 0.318 0.000
M86.9 Osteomyelitis, unspecified
0.681 0.318 0.000
I70 Atherosclerosis
0.681 0.319 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.681 0.319 0.000
X60-X84 Intentional self-harm
0.681 0.319 0.000
L54 Erythema in diseases classified elsewhere
0.680 0.320 0.000
L51 Erythema multiforme
0.680 0.320 0.000
L50 Urticaria
0.680 0.320 0.000
L52 Erythema nodosum
0.680 0.320 0.000
F42 Obsessive-compulsive disorder
0.680 0.320 0.000
T92.1 Sequelae of fracture of arm
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.679 0.321 0.000
G93.3 Postviral fatigue syndrome
0.679 0.321 0.000
L30 Other dermatitis
0.678 0.322 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.678 0.322 0.000
M79.63 Pain in limb (Forearm)
0.677 0.323 0.000
N03 Chronic nephritic syndrome
0.677 0.323 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.676 0.324 0.000
N30.0 Acute cystitis
0.675 0.325 0.000
E20-E35 Disorders of other endocrine glands
0.675 0.325 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.674 0.326 0.000
M81 Osteoporosis without pathological fracture
0.673 0.327 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
M12 Other specific arthropathies
0.671 0.329 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.671 0.329 0.000
M08 Juvenile arthritis
0.671 0.329 0.000
Y45.0 Opioids and related analgesics
0.671 0.329 0.000
I95.9 Hypotension, unspecified
0.670 0.330 0.000
N30.3 Trigonitis
0.670 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.670 0.330 0.000
G57 Mononeuropathies of lower limb
0.670 0.330 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.669 0.331 0.000
O81 Single delivery by forceps and vacuum extractor
0.668 0.331 0.000
W00-W19 Falls
0.668 0.332 0.000
M90 Osteopathies in diseases classified elsewhere
0.668 0.332 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.668 0.332 0.000
L03.9 Cellulitis, unspecified
0.668 0.332 0.000
K85.1 Biliary acute pancreatitis
0.666 0.334 0.000
M79.67 Pain in limb (Ankle and foot)
0.665 0.334 0.000
L04 Acute lymphadenitis
0.665 0.335 0.000
L01 Impetigo
0.665 0.335 0.000
L00 Staphylococcal scalded skin syndrome
0.665 0.335 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.665 0.335 0.000
M84 Disorders of continuity of bone
0.665 0.335 0.000
E50-E64 Other nutritional deficiencies
0.664 0.336 0.000
Chapter VIII Diseases of the ear and mastoid process
0.663 0.337 0.000
S20-S29 Injuries to the thorax
0.662 0.338 0.000
N10-N16 Renal tubulo-interstitial diseases
0.662 0.338 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.661 0.339 0.000
M77.4 Metatarsalgia
0.661 0.339 0.000
L25 Unspecified contact dermatitis
0.661 0.339 0.000
L24 Irritant contact dermatitis
0.661 0.339 0.000
L23 Allergic contact dermatitis
0.661 0.339 0.000
L21 Seborrhoeic dermatitis
0.661 0.339 0.000
L20 Atopic dermatitis
0.661 0.339 0.000
L26 Exfoliative dermatitis
0.661 0.339 0.000
L22 Diaper [napkin] dermatitis
0.661 0.339 0.000
M07 Psoriatic and enteropathic arthropathies
0.660 0.340 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.659 0.341 0.000
I07 Rheumatic tricuspid valve diseases
0.659 0.341 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.657 0.342 0.000
F48 Other neurotic disorders
0.657 0.343 0.000
F44 Dissociative [conversion] disorders
0.657 0.343 0.000
K66.8 Other specified disorders of peritoneum
0.657 0.343 0.000
L53.8 Other specified erythematous conditions
0.656 0.343 0.000
L53.3 Other chronic figurate erythema
0.656 0.343 0.000
L53.2 Erythema marginatum
0.656 0.343 0.000
L53.1 Erythema annulare centrifugum
0.656 0.343 0.000
L53.0 Toxic erythema
0.656 0.343 0.000
H55-H59 Other disorders of eye and adnexa
0.656 0.344 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.655 0.345 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.654 0.346 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.654 0.346 0.000
I67.5 Moyamoya disease
0.654 0.346 0.000
I67.4 Hypertensive encephalopathy
0.654 0.346 0.000
I67.3 Progressive vascular leukoencephalopathy
0.654 0.346 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.654 0.346 0.000
M21 Other acquired deformities of limbs
0.654 0.346 0.000
N32.1 Vesicointestinal fistula
0.653 0.347 0.000
M13.0 Polyarthritis, unspecified
0.653 0.347 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.652 0.348 0.000
A48 Other bacterial diseases, not elsewhere classified
0.652 0.348 0.000
A44 Bartonellosis
0.652 0.348 0.000
A43 Nocardiosis
0.652 0.348 0.000
A42 Actinomycosis
0.652 0.348 0.000
A39 Meningococcal infection
0.652 0.348 0.000
A37 Whooping cough
0.652 0.348 0.000
A36 Diphtheria
0.652 0.348 0.000
A32 Listeriosis
0.652 0.348 0.000
A31 Infection due to other mycobacteria
0.652 0.348 0.000
A30 Leprosy [Hansen's disease]
0.652 0.348 0.000
A46 Erysipelas
0.652 0.348 0.000
A38 Scarlet fever
0.652 0.348 0.000
A35 Other tetanus
0.652 0.348 0.000
A34 Obstetrical tetanus
0.652 0.348 0.000
A33 Tetanus neonatorum
0.652 0.348 0.000
M24 Other specific joint derangements
0.651 0.349 0.000
S70-S79 Injuries to the hip and thigh
0.651 0.349 0.000
R42 Dizziness and giddiness
0.650 0.350 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.650 0.350 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.650 0.350 0.000
K44 Diaphragmatic hernia
0.650 0.350 0.000
Y40.0 Penicillins
0.649 0.351 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.649 0.351 0.000
B25-B34 Other viral diseases
0.648 0.352 0.000
F99-F99 Unspecified mental disorder
0.648 0.352 0.000
T98 Sequelae of other and unspecified effects of external causes
0.648 0.352 0.000
T95 Sequelae of burns, corrosions and frostbite
0.648 0.352 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.648 0.352 0.000
T91 Sequelae of injuries of neck and trunk
0.648 0.352 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.648 0.352 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.648 0.352 0.000
T79-T79 Certain early complications of trauma
0.647 0.353 0.000
F43 Reaction to severe stress, and adjustment disorders
0.647 0.353 0.000
G93.8 Other specified disorders of brain
0.647 0.353 0.000
I74 Arterial embolism and thrombosis
0.645 0.355 0.000
Y44 Agents primarily affecting blood constituents
0.644 0.355 0.000
M79.10 Myalgia (Multiple sites)
0.644 0.356 0.000
M49 Spondylopathies in diseases classified elsewhere
0.641 0.358 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.641 0.359 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.641 0.359 0.000
I99 Other and unspecified disorders of circulatory system
0.641 0.359 0.000
M79.18 Myalgia (Other)
0.640 0.359 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.640 0.359 0.000
M99 Biomechanical lesions, not elsewhere classified
0.640 0.360 0.000
R15 Faecal incontinence
0.640 0.360 0.000
E85 Amyloidosis
0.640 0.360 0.000
E84 Cystic fibrosis
0.640 0.360 0.000
E79 Disorders of purine and pyrimidine metabolism
0.640 0.360 0.000
E77 Disorders of glycoprotein metabolism
0.640 0.360 0.000
E76 Disorders of glycosaminoglycan metabolism
0.640 0.360 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.640 0.360 0.000
E74 Other disorders of carbohydrate metabolism
0.640 0.360 0.000
E72 Other disorders of amino-acid metabolism
0.640 0.360 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.640 0.360 0.000
E70 Disorders of aromatic amino-acid metabolism
0.640 0.360 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.640 0.360 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.639 0.361 0.000
Y45.8 Other analgesics and antipyretics
0.639 0.361 0.000
Y45.5 4-Aminophenol derivatives
0.639 0.361 0.000
Y45.4 Antirheumatics
0.639 0.361 0.000
Y45.2 Propionic acid derivatives
0.639 0.361 0.000
Y45.1 Salicylates
0.639 0.361 0.000
K70-K77 Diseases of liver
0.639 0.361 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.638 0.361 0.000
N62 Hypertrophy of breast
0.638 0.362 0.000
N36.2 Urethral caruncle
0.638 0.362 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.637 0.363 0.000
E65-E68 Obesity and other hyperalimentation
0.637 0.363 0.000
T13 Other injuries of lower limb, level unspecified
0.637 0.363 0.000
H10-H13 Disorders of conjunctiva
0.637 0.363 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.636 0.364 0.000
M79.69 Pain in limb (Site unspecified)
0.636 0.364 0.000
I63.8 Other cerebral infarction
0.635 0.365 0.000
M79.64 Pain in limb (Hand)
0.635 0.365 0.000
F40.2 Specific (isolated) phobias
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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