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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114648712
log Bayes Factor = 13.5632
Chromosome 4   position 189,742,953  (GRCh37) Explore rs114648712 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter II Neoplasms
0.998 0.002 0.000
C64-C68 Malignant neoplasms of urinary tract
0.995 0.005 0.000
S80-S89 Injuries to the knee and lower leg
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
C67 Malignant neoplasm of bladder
0.990 0.010 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
S00-S09 Injuries to the head
0.985 0.015 0.000
S82 Fracture of lower leg, including ankle
0.985 0.015 0.000
S82.8 Fractures of other parts of lower leg
0.982 0.018 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.981 0.019 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.980 0.020 0.000
C67.9 Bladder, unspecified
0.978 0.022 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.972 0.028 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.971 0.029 0.000
J40-J47 Chronic lower respiratory diseases
0.969 0.031 0.000
Chapter XIV Diseases of the genitourinary system
0.968 0.032 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.965 0.035 0.000
Chapter V Mental and behavioural disorders
0.965 0.035 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.963 0.037 0.000
N84 Polyp of female genital tract
0.963 0.037 0.000
N84.0 Polyp of corpus uteri
0.956 0.044 0.000
H25-H28 Disorders of lens
0.956 0.044 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
H53-H54 Visual disturbances and blindness
0.941 0.059 0.000
J47 Bronchiectasis
0.938 0.062 0.000
J60-J70 Lung diseases due to external agents
0.935 0.065 0.000
S01 Open wound of head
0.934 0.066 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.933 0.067 0.000
J90-J94 Other diseases of pleura
0.930 0.070 0.000
N92 Excessive, frequent and irregular menstruation
0.930 0.070 0.000
T93 Sequelae of injuries of lower limb
0.928 0.072 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.925 0.075 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.923 0.077 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.919 0.081 0.000
H25 Senile cataract
0.919 0.081 0.000
S00 Superficial injury of head
0.912 0.088 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.909 0.091 0.000
D50-D53 Nutritional anaemias
0.906 0.094 0.000
J40 Bronchitis, not specified as acute or chronic
0.903 0.097 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.900 0.100 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.894 0.106 0.000
W00-W19 Falls
0.893 0.107 0.000
N80 Endometriosis
0.891 0.109 0.000
J90 Pleural effusion, not elsewhere classified
0.884 0.116 0.000
E10-E14 Diabetes mellitus
0.883 0.117 0.000
J00-J06 Acute upper respiratory infections
0.882 0.118 0.000
D51 Vitamin B12 deficiency anaemia
0.880 0.120 0.000
J69 Pneumonitis due to solids and liquids
0.880 0.120 0.000
L60-L75 Disorders of skin appendages
0.878 0.122 0.000
Y85 Sequelae of transport accidents
0.877 0.123 0.000
N86 Erosion and ectropion of cervix uteri
0.877 0.123 0.000
E10 Insulin-dependent diabetes mellitus
0.876 0.124 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.876 0.124 0.000
I71 Aortic aneurysm and dissection
0.875 0.125 0.000
I05-I09 Chronic rheumatic heart diseases
0.874 0.126 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.871 0.129 0.000
E10.9 Without complications
0.870 0.130 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.870 0.130 0.000
H25.0 Senile incipient cataract
0.868 0.132 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.867 0.133 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.867 0.133 0.000
I70 Atherosclerosis
0.865 0.135 0.000
N99-N99 Other disorders of the genitourinary system
0.862 0.138 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.861 0.139 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.851 0.149 0.000
I10-I15 Hypertensive diseases
0.851 0.149 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.850 0.150 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.848 0.152 0.000
H53 Visual disturbances
0.844 0.156 0.000
Y85.0 Sequelae of motor-vehicle accident
0.842 0.158 0.000
I60-I69 Cerebrovascular diseases
0.842 0.158 0.000
M80-M85 Disorders of bone density and structure
0.841 0.159 0.000
I74 Arterial embolism and thrombosis
0.840 0.160 0.000
J69.0 Pneumonitis due to food and vomit
0.840 0.160 0.000
H55-H59 Other disorders of eye and adnexa
0.840 0.160 0.000
H54 Blindness and low vision
0.838 0.162 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.837 0.163 0.000
H25.9 Senile cataract, unspecified
0.835 0.165 0.000
T93.2 Sequelae of other fractures of lower limb
0.833 0.167 0.000
N80.1 Endometriosis of ovary
0.833 0.167 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.831 0.169 0.000
S86 Injury of muscle and tendon at lower leg level
0.825 0.175 0.000
V10-V19 Pedal cyclist injured in transport accident
0.823 0.177 0.000
E20-E35 Disorders of other endocrine glands
0.823 0.177 0.000
T90 Sequelae of injuries of head
0.821 0.179 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.820 0.180 0.000
Y44 Agents primarily affecting blood constituents
0.815 0.185 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.814 0.186 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.814 0.186 0.000
C67.4 Posterior wall of bladder
0.813 0.187 0.000
S10-S19 Injuries to the neck
0.812 0.188 0.000
M65-M68 Disorders of synovium and tendon
0.812 0.188 0.000
S90-S99 Injuries to the ankle and foot
0.810 0.190 0.000
J20-J22 Other acute lower respiratory infections
0.809 0.191 0.000
N84.1 Polyp of cervix uteri
0.808 0.192 0.000
J09-J18 Influenza and pneumonia
0.808 0.192 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.807 0.193 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.807 0.193 0.000
Y52 Agents primarily affecting the cardiovascular system
0.806 0.194 0.000
S01.2 Open wound of nose
0.805 0.195 0.000
C67.5 Bladder neck
0.805 0.195 0.000
J30-J39 Other diseases of upper respiratory tract
0.804 0.196 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.800 0.200 0.000
C51-C58 Malignant neoplasms of female genital organs
0.799 0.201 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.798 0.202 0.000
I26 Pulmonary embolism
0.798 0.202 0.000
S00.0 Superficial injury of scalp
0.798 0.202 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.795 0.205 0.000
I72 Other aneurysm
0.795 0.205 0.000
H10-H13 Disorders of conjunctiva
0.795 0.205 0.000
N84.3 Polyp of vulva
0.794 0.206 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.794 0.206 0.000
D80-D89 Certain disorders involving the immune mechanism
0.793 0.207 0.000
S82.5 Fracture of medial malleolus
0.792 0.208 0.000
N92.3 Ovulation bleeding
0.791 0.209 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.790 0.210 0.000
S60-S69 Injuries to the wrist and hand
0.789 0.211 0.000
J44 Other chronic obstructive pulmonary disease
0.789 0.211 0.000
S82.81 Fractures of other parts of lower leg (open)
0.788 0.212 0.000
D68 Other coagulation defects
0.788 0.212 0.000
W19 Unspecified fall
0.787 0.213 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.787 0.213 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.785 0.215 0.000
Q50-Q56 Congenital malformations of genital organs
0.781 0.219 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.780 0.220 0.000
C67.1 Dome of bladder
0.780 0.220 0.000
S89 Other and unspecified injuries of lower leg
0.778 0.222 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.776 0.224 0.000
Chapter VI Diseases of the nervous system
0.774 0.226 0.000
N80.3 Endometriosis of pelvic peritoneum
0.774 0.226 0.000
I73 Other peripheral vascular diseases
0.773 0.227 0.000
S01.9 Open wound of head, part unspecified
0.771 0.229 0.000
I10 Essential (primary) hypertension
0.769 0.231 0.000
Q21 Congenital malformations of cardiac septa
0.769 0.231 0.000
S01.5 Open wound of lip and oral cavity
0.766 0.234 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.766 0.234 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.766 0.234 0.000
J00 Acute nasopharyngitis [common cold]
0.766 0.234 0.000
H26 Other cataract
0.764 0.236 0.000
F17.1 Harmful use
0.762 0.238 0.000
M67 Other disorders of synovium and tendon
0.762 0.238 0.000
J80 Adult respiratory distress syndrome
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.759 0.241 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.758 0.242 0.000
I08 Multiple valve diseases
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.756 0.244 0.000
J34 Other disorders of nose and nasal sinuses
0.756 0.244 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.755 0.245 0.000
F10.0 Acute intoxication
0.752 0.248 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.752 0.248 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.752 0.248 0.000
J84 Other interstitial pulmonary diseases
0.751 0.249 0.000
Y57 Other and unspecified drugs and medicaments
0.751 0.249 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.750 0.250 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.750 0.250 0.000
I69 Sequelae of cerebrovascular disease
0.749 0.251 0.000
Q60-Q64 Congenital malformations of the urinary system
0.747 0.253 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.746 0.254 0.000
I63 Cerebral infarction
0.744 0.256 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.743 0.257 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.743 0.257 0.000
M86-M90 Other osteopathies
0.742 0.258 0.000
S01.8 Open wound of other parts of head
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.742 0.258 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.742 0.258 0.000
H25.8 Other senile cataract
0.741 0.259 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.736 0.264 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.736 0.264 0.000
W18 Other fall on same level
0.736 0.264 0.000
D00-D09 In situ neoplasms
0.735 0.265 0.000
S00.7 Multiple superficial injuries of head
0.735 0.265 0.000
N80.5 Endometriosis of intestine
0.734 0.266 0.000
S02 Fracture of skull and facial bones
0.733 0.266 0.000
C34 Malignant neoplasm of bronchus and lung
0.733 0.267 0.000
L91 Hypertrophic disorders of skin
0.733 0.267 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.732 0.267 0.000
C67.2 Lateral wall of bladder
0.732 0.268 0.000
H40-H42 Glaucoma
0.731 0.269 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.731 0.269 0.000
Chapter XXII Codes for special purposes
0.730 0.270 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.729 0.271 0.000
L20-L30 Dermatitis and eczema
0.728 0.272 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.728 0.272 0.000
M84 Disorders of continuity of bone
0.727 0.273 0.000
N10-N16 Renal tubulo-interstitial diseases
0.726 0.274 0.000
S09 Other and unspecified injuries of head
0.726 0.274 0.000
S50-S59 Injuries to the elbow and forearm
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.724 0.275 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.723 0.277 0.000
J94 Other pleural conditions
0.723 0.277 0.000
F10.3 Withdrawal state
0.722 0.278 0.000
H53.2 Diplopia
0.722 0.278 0.000
H43-H45 Disorders of vitreous body and globe
0.722 0.278 0.000
J91 Pleural effusion in conditions classified elsewhere
0.721 0.279 0.000
T92 Sequelae of injuries of upper limb
0.721 0.279 0.000
S01.1 Open wound of eyelid and periocular area
0.720 0.280 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.720 0.280 0.000
F80-F89 Disorders of psychological development
0.720 0.280 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.719 0.281 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.719 0.281 0.000
T91 Sequelae of injuries of neck and trunk
0.719 0.281 0.000
S06 Intracranial injury
0.719 0.281 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.282 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.718 0.282 0.000
J02 Acute pharyngitis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.717 0.283 0.000
D48.5 Skin
0.717 0.283 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X50-X57 Overexertion, travel and privation
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V80-V89 Other land transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
M80 Osteoporosis with pathological fracture
0.714 0.286 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.713 0.287 0.000
C66 Malignant neoplasm of ureter
0.713 0.287 0.000
C65 Malignant neoplasm of renal pelvis
0.713 0.287 0.000
S88 Traumatic amputation of lower leg
0.712 0.287 0.000
S87 Crushing injury of lower leg
0.712 0.287 0.000
S85 Injury of blood vessels at lower leg level
0.712 0.287 0.000
S84 Injury of nerves at lower leg level
0.712 0.287 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.712 0.288 0.000
L85 Other epidermal thickening
0.712 0.288 0.000
N88 Other noninflammatory disorders of cervix uteri
0.712 0.288 0.000
S82.1 Fracture of upper end of tibia
0.711 0.289 0.000
G30-G32 Other degenerative diseases of the nervous system
0.711 0.289 0.000
Q21.1 Atrial septal defect
0.711 0.289 0.000
C32 Malignant neoplasm of larynx
0.710 0.290 0.000
C67.8 Overlapping lesion of bladder
0.710 0.290 0.000
C67.7 Urachus
0.710 0.290 0.000
C67.3 Anterior wall of bladder
0.710 0.290 0.000
C67.0 Trigone of bladder
0.710 0.290 0.000
C77.3 Axillary and upper limb lymph nodes
0.709 0.291 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
F99-F99 Unspecified mental disorder
0.706 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.706 0.294 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S05 Injury of eye and orbit
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
S82.9 Fracture of lower leg, part unspecified
0.706 0.294 0.000
S82.7 Multiple fractures of lower leg
0.706 0.294 0.000
C67.6 Ureteric orifice
0.706 0.294 0.000
N92.6 Irregular menstruation, unspecified
0.705 0.295 0.000
S82.86 Maisonneuve's fracture
0.704 0.296 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.704 0.296 0.000
N92.5 Other specified irregular menstruation
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.703 0.297 0.000
Y58 Bacterial vaccines
0.703 0.297 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.703 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.703 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.703 0.297 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
Y48 Anaesthetics and therapeutic gases
0.703 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.703 0.297 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
D48.7 Other specified sites
0.701 0.299 0.000
S80 Superficial injury of lower leg
0.700 0.299 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.700 0.300 0.000
S00.3 Superficial injury of nose
0.700 0.300 0.000
C15-C26 Malignant neoplasms of digestive organs
0.700 0.300 0.000
I07 Rheumatic tricuspid valve diseases
0.699 0.301 0.000
S00.9 Superficial injury of head, part unspecified
0.699 0.301 0.000
W19.4 Street and highway
0.698 0.302 0.000
Y40 Systemic antibiotics
0.698 0.302 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.698 0.302 0.000
L70 Acne
0.698 0.302 0.000
T98 Sequelae of other and unspecified effects of external causes
0.697 0.303 0.000
T95 Sequelae of burns, corrosions and frostbite
0.697 0.303 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.697 0.303 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.697 0.303 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.697 0.303 0.000
F17.2 Dependence syndrome
0.697 0.303 0.000
Y44.2 Anticoagulants
0.696 0.304 0.000
H53.1 Subjective visual disturbances
0.696 0.304 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.696 0.304 0.000
J41 Simple and mucopurulent chronic bronchitis
0.695 0.305 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.694 0.306 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.694 0.306 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.694 0.306 0.000
S01.7 Multiple open wounds of head
0.693 0.307 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.693 0.307 0.000
N98 Complications associated with artificial fertilisation
0.692 0.308 0.000
N91 Absent, scanty and rare menstruation
0.692 0.308 0.000
N82 Fistulae involving female genital tract
0.692 0.308 0.000
N96 Habitual aborter
0.692 0.308 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.691 0.308 0.000
F70-F79 Mental retardation
0.691 0.308 0.000
H53.4 Visual field defects
0.691 0.309 0.000
N84.2 Polyp of vagina
0.691 0.309 0.000
D55-D59 Haemolytic anaemias
0.690 0.310 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.690 0.310 0.000
N84.9 Polyp of female genital tract, unspecified
0.690 0.310 0.000
N84.8 Polyp of other parts of female genital tract
0.690 0.310 0.000
M50-M54 Other dorsopathies
0.690 0.310 0.000
L73 Other follicular disorders
0.689 0.311 0.000
N25-N29 Other disorders of kidney and ureter
0.688 0.312 0.000
E22 Hyperfunction of pituitary gland
0.687 0.313 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.687 0.313 0.000
J18 Pneumonia, organism unspecified
0.687 0.313 0.000
E34 Other endocrine disorders
0.687 0.313 0.000
S20-S29 Injuries to the thorax
0.686 0.314 0.000
D45 Polycythaemia vera
0.686 0.314 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.685 0.315 0.000
H27 Other disorders of lens
0.685 0.315 0.000
D48.0 Bone and articular cartilage
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
C50-C50 Malignant neoplasm of breast
0.683 0.317 0.000
E23 Hypofunction and other disorders of pituitary gland
0.682 0.318 0.000
I11 Hypertensive heart disease
0.682 0.318 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.682 0.318 0.000
Q80-Q89 Other congenital malformations
0.682 0.318 0.000
Q35-Q37 Cleft lip and cleft palate
0.682 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.682 0.318 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.682 0.318 0.000
H18 Other disorders of cornea
0.682 0.318 0.000
D66 Hereditary factor VIII deficiency
0.682 0.318 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.681 0.318 0.000
H21 Other disorders of iris and ciliary body
0.681 0.319 0.000
J03 Acute tonsillitis
0.680 0.320 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.680 0.320 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.679 0.321 0.000
H53.0 Amblyopia ex anopsia
0.679 0.321 0.000
I74.8 Embolism and thrombosis of other arteries
0.679 0.321 0.000
I73.9 Peripheral vascular disease, unspecified
0.678 0.322 0.000
Chapter VIII Diseases of the ear and mastoid process
0.678 0.322 0.000
H54.4 Blindness, one eye
0.678 0.322 0.000
N93 Other abnormal uterine and vaginal bleeding
0.678 0.322 0.000
C91 Lymphoid leukaemia
0.678 0.322 0.000
H54.7 Unspecified visual loss
0.678 0.322 0.000
F22 Persistent delusional disorders
0.676 0.323 0.000
J81 Pulmonary oedema
0.675 0.324 0.000
S82.4 Fracture of fibula alone
0.674 0.325 0.000
H11 Other disorders of conjunctiva
0.674 0.326 0.000
M81 Osteoporosis without pathological fracture
0.674 0.326 0.000
M67.8 Other specified disorders of synovium and tendon
0.674 0.326 0.000
L60 Nail disorders
0.673 0.327 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.673 0.327 0.000
Y45.0 Opioids and related analgesics
0.673 0.327 0.000
D48.1 Connective and other soft tissue
0.673 0.327 0.000
J35 Chronic diseases of tonsils and adenoids
0.672 0.328 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.672 0.328 0.000
J22 Unspecified acute lower respiratory infection
0.672 0.328 0.000
M91-M94 Chondropathies
0.671 0.329 0.000
S01.0 Open wound of scalp
0.671 0.329 0.000
J70 Respiratory conditions due to other external agents
0.670 0.330 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.670 0.330 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.670 0.330 0.000
J66 Airway disease due to specific organic dust
0.670 0.330 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.670 0.330 0.000
J62 Pneumoconiosis due to dust containing silica
0.670 0.330 0.000
J65 Pneumoconiosis associated with tuberculosis
0.670 0.330 0.000
J64 Unspecified pneumoconiosis
0.670 0.330 0.000
J60 Coalworker's pneumoconiosis
0.670 0.330 0.000
S01.4 Open wound of cheek and temporomandibular area
0.670 0.330 0.000
F20 Schizophrenia
0.669 0.331 0.000
L10-L14 Bullous disorders
0.669 0.331 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.669 0.331 0.000
S19 Other and unspecified injuries of neck
0.668 0.332 0.000
N76 Other inflammation of vagina and vulva
0.667 0.333 0.000
N92.2 Excessive menstruation at puberty
0.667 0.333 0.000
L72.0 Epidermal cyst
0.666 0.334 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.666 0.334 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.665 0.335 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.665 0.335 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.665 0.335 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.665 0.335 0.000
T93.1 Sequelae of fracture of femur
0.665 0.335 0.000
T93.0 Sequelae of open wound of lower limb
0.665 0.335 0.000
E10.3 With ophthalmic complications
0.665 0.335 0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level
0.664 0.335 0.000
N80.2 Endometriosis of Fallopian tube
0.664 0.336 0.000
E28 Ovarian dysfunction
0.663 0.337 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.663 0.337 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.663 0.337 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.663 0.337 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.663 0.337 0.000
H26.4 After-cataract
0.663 0.337 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.662 0.338 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.662 0.338 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.662 0.338 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.662 0.338 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.662 0.338 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.662 0.338 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.662 0.338 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.662 0.338 0.000
F11 Mental and behavioural disorders due to use of opioids
0.662 0.338 0.000
T90.4 Sequelae of injury of eye and orbit
0.662 0.338 0.000
L65 Other nonscarring hair loss
0.661 0.338 0.000
N00-N08 Glomerular diseases
0.660 0.340 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.660 0.340 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.659 0.341 0.000
Y89 Sequelae of other external causes
0.659 0.341 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.659 0.341 0.000
H25.2 Senile cataract, morgagnian type
0.659 0.341 0.000
J42 Unspecified chronic bronchitis
0.659 0.341 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.658 0.341 0.000
E10.5 With peripheral circulatory complications
0.658 0.342 0.000
E13 Other specified diabetes mellitus
0.658 0.342 0.000
Y43 Primarily systemic agents
0.658 0.342 0.000
C54 Malignant neoplasm of corpus uteri
0.657 0.343 0.000
J32 Chronic sinusitis
0.656 0.344 0.000
X60-X84 Intentional self-harm
0.656 0.344 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.656 0.344 0.000
M00-M03 Infectious arthropathies
0.655 0.345 0.000
D48.6 Breast
0.655 0.345 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.346 0.000
S82.50 Fracture of medial malleolus (closed)
0.654 0.346 0.000
S00.5 Superficial injury of lip and oral cavity
0.654 0.346 0.000
S00.4 Superficial injury of ear
0.654 0.346 0.000
Q63 Other congenital malformations of kidney
0.653 0.346 0.000
W10 Fall on and from stairs and steps
0.653 0.347 0.000
F10.4 Withdrawal state with delirium
0.652 0.348 0.000
E40-E46 Malnutrition
0.651 0.348 0.000
F60-F69 Disorders of adult personality and behaviour
0.651 0.349 0.000
L71 Rosacea
0.651 0.349 0.000
Y54.5 Other diuretics
0.651 0.349 0.000
S81 Open wound of lower leg
0.651 0.349 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.650 0.350 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.650 0.350 0.000
D53 Other nutritional anaemias
0.650 0.350 0.000
N13 Obstructive and reflux uropathy
0.649 0.351 0.000
S90 Superficial injury of ankle and foot
0.649 0.351 0.000
W13 Fall from, out of or through building or structure
0.648 0.351 0.000
I71.0 Dissection of aorta [any part]
0.648 0.351 0.000
N85.4 Malposition of uterus
0.648 0.352 0.000
L91.8 Other hypertrophic disorders of skin
0.648 0.352 0.000
J04 Acute laryngitis and tracheitis
0.648 0.352 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.648 0.352 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.647 0.353 0.000
E10.4 With neurological complications
0.646 0.354 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.645 0.355 0.000
M45-M49 Spondylopathies
0.645 0.355 0.000
N99.1 Postprocedural urethral stricture
0.645 0.355 0.000
M40-M43 Deforming dorsopathies
0.645 0.355 0.000
H54.9 Unspecified visual impairment (binocular)
0.644 0.356 0.000
H54.0 Blindness, both eyes
0.643 0.357 0.000
M82 Osteoporosis in diseases classified elsewhere
0.643 0.357 0.000
H55 Nystagmus and other irregular eye movements
0.642 0.358 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.642 0.358 0.000
S82.2 Fracture of shaft of tibia
0.642 0.358 0.000
S64 Injury of nerves at wrist and hand level
0.641 0.359 0.000
M60-M63 Disorders of muscles
0.641 0.359 0.000
W17 Other fall from one level to another
0.640 0.360 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.640 0.360 0.000
W15 Fall from cliff
0.640 0.360 0.000
W14 Fall from tree
0.640 0.360 0.000
W12 Fall on and from scaffolding
0.640 0.360 0.000
W11 Fall on and from ladder
0.640 0.360 0.000
W09 Fall involving playground equipment
0.640 0.360 0.000
W08 Fall involving other furniture
0.640 0.360 0.000
W06 Fall involving bed
0.640 0.360 0.000
W05 Fall involving wheelchair
0.640 0.360 0.000
W04 Fall while being carried or supported by other persons
0.640 0.360 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.640 0.360 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.640 0.360 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.640 0.360 0.000
W00 Fall on same level involving ice and snow
0.640 0.360 0.000
S40-S49 Injuries to the shoulder and upper arm
0.640 0.360 0.000
N80.6 Endometriosis in cutaneous scar
0.639 0.361 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.639 0.361 0.000
I78 Diseases of capillaries
0.638 0.362 0.000
W20-W49 Exposure to inanimate mechanical forces
0.638 0.362 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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