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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114709725
log Bayes Factor = 15.4695
Chromosome 2   position 207,557,965  (GRCh37) Explore rs114709725 on Ensembl!
Variant rs114709725 is part of Cluster X0237

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
K29 Gastritis and duodenitis
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.991 0.009 0.000
K21 Gastro-oesophageal reflux disease
0.989 0.011 0.000
K29.8 Duodenitis
0.987 0.013 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.984 0.016 0.000
A00-A09 Intestinal infectious diseases
0.981 0.019 0.000
I10-I15 Hypertensive diseases
0.978 0.022 0.000
K50-K52 Noninfective enteritis and colitis
0.974 0.026 0.000
K22 Other diseases of oesophagus
0.974 0.026 0.000
J30-J39 Other diseases of upper respiratory tract
0.968 0.032 0.000
J90-J94 Other diseases of pleura
0.967 0.033 0.000
K26 Duodenal ulcer
0.966 0.034 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.965 0.035 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.960 0.040 0.000
I10 Essential (primary) hypertension
0.960 0.040 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.954 0.046 0.000
H30-H36 Disorders of choroid and retina
0.949 0.051 0.000
K52 Other non-infective gastro-enteritis and colitis
0.944 0.056 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.943 0.057 0.000
E11.3 With ophthalmic complications
0.940 0.060 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.938 0.062 0.000
H10-H13 Disorders of conjunctiva
0.938 0.062 0.000
E11.9 Without complications
0.938 0.062 0.000
H40-H42 Glaucoma
0.935 0.065 0.000
J34 Other disorders of nose and nasal sinuses
0.932 0.068 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.930 0.070 0.000
E70-E90 Metabolic disorders
0.930 0.070 0.000
K29.5 Chronic gastritis, unspecified
0.925 0.075 0.000
J90 Pleural effusion, not elsewhere classified
0.922 0.078 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.922 0.078 0.000
H33 Retinal detachments and breaks
0.916 0.084 0.000
Chapter II Neoplasms
0.908 0.092 0.000
E20-E35 Disorders of other endocrine glands
0.905 0.095 0.000
H53-H54 Visual disturbances and blindness
0.902 0.098 0.000
Chapter V Mental and behavioural disorders
0.902 0.098 0.000
K22.2 Oesophageal obstruction
0.900 0.100 0.000
J40-J47 Chronic lower respiratory diseases
0.899 0.101 0.000
I26 Pulmonary embolism
0.898 0.102 0.000
H11 Other disorders of conjunctiva
0.894 0.106 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.893 0.107 0.000
H40 Glaucoma
0.889 0.111 0.000
I95 Hypotension
0.887 0.113 0.000
K29.4 Chronic atrophic gastritis
0.883 0.117 0.000
E50-E64 Other nutritional deficiencies
0.883 0.117 0.000
Chapter VIII Diseases of the ear and mastoid process
0.879 0.121 0.000
K25 Gastric ulcer
0.877 0.123 0.000
K31 Other diseases of stomach and duodenum
0.872 0.128 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.863 0.137 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.861 0.139 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.860 0.140 0.000
F30-F39 Mood [affective] disorders
0.860 0.140 0.000
H33.0 Retinal detachment with retinal break
0.859 0.141 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.859 0.141 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.853 0.147 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.852 0.148 0.000
E11.4 With neurological complications
0.851 0.149 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.845 0.155 0.000
I27 Other pulmonary heart diseases
0.843 0.157 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.843 0.157 0.000
Chapter VI Diseases of the nervous system
0.843 0.157 0.000
J30 Vasomotor and allergic rhinitis
0.843 0.157 0.000
A04 Other bacterial intestinal infections
0.837 0.163 0.000
J44 Other chronic obstructive pulmonary disease
0.837 0.163 0.000
I95.9 Hypotension, unspecified
0.834 0.166 0.000
E11.5 With peripheral circulatory complications
0.833 0.167 0.000
H43-H45 Disorders of vitreous body and globe
0.831 0.169 0.000
H53 Visual disturbances
0.831 0.169 0.000
C64-C68 Malignant neoplasms of urinary tract
0.826 0.174 0.000
J60-J70 Lung diseases due to external agents
0.824 0.176 0.000
H40.1 Primary open-angle glaucoma
0.822 0.178 0.000
E14 Unspecified diabetes mellitus
0.820 0.180 0.000
J95-J99 Other diseases of the respiratory system
0.817 0.183 0.000
E78.0 Pure hypercholesterolaemia
0.813 0.187 0.000
E55 Vitamin D deficiency
0.812 0.188 0.000
J93 Pneumothorax
0.810 0.190 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.809 0.191 0.000
H36 Retinal disorders in diseases classified elsewhere
0.808 0.192 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.808 0.192 0.000
B15-B19 Viral hepatitis
0.807 0.193 0.000
E86 Volume depletion
0.804 0.196 0.000
J36 Peritonsillar abscess
0.803 0.197 0.000
K22.1 Ulcer of oesophagus
0.803 0.197 0.000
F32 Depressive episode
0.803 0.197 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.802 0.198 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.799 0.201 0.000
K51 Ulcerative colitis
0.799 0.201 0.000
D75 Other diseases of blood and blood-forming organs
0.797 0.203 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.796 0.204 0.000
K70-K77 Diseases of liver
0.795 0.205 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.793 0.207 0.000
K90-K93 Other diseases of the digestive system
0.793 0.207 0.000
I05-I09 Chronic rheumatic heart diseases
0.789 0.211 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.788 0.212 0.000
H40.0 Glaucoma suspect
0.787 0.213 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.787 0.213 0.000
H33.1 Retinoschisis and retinal cysts
0.786 0.214 0.000
H33.2 Serous retinal detachment
0.781 0.219 0.000
D60-D64 Aplastic and other anaemias
0.780 0.220 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.780 0.220 0.000
B07 Viral warts
0.780 0.220 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.777 0.223 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.777 0.223 0.000
K22.7 Barrett's oesophagus
0.776 0.224 0.000
K29.3 Chronic superficial gastritis
0.773 0.227 0.000
I12 Hypertensive renal disease
0.770 0.230 0.000
G62 Other polyneuropathies
0.767 0.233 0.000
J32 Chronic sinusitis
0.765 0.235 0.000
M05-M14 Inflammatory polyarthropathies
0.764 0.236 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.764 0.236 0.000
F31 Bipolar affective disorder
0.763 0.237 0.000
J00-J06 Acute upper respiratory infections
0.763 0.237 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.761 0.239 0.000
H53.8 Other visual disturbances
0.761 0.239 0.000
E55.9 Vitamin D deficiency, unspecified
0.761 0.239 0.000
A30-A49 Other bacterial diseases
0.760 0.240 0.000
E27 Other disorders of adrenal gland
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
K31.7 Polyp of stomach and duodenum
0.758 0.242 0.000
J34.3 Hypertrophy of nasal turbinates
0.757 0.243 0.000
J47 Bronchiectasis
0.756 0.244 0.000
H11.0 Pterygium
0.755 0.245 0.000
F32.9 Depressive episode, unspecified
0.753 0.247 0.000
E40-E46 Malnutrition
0.752 0.248 0.000
J94 Other pleural conditions
0.752 0.248 0.000
H11.8 Other specified disorders of conjunctiva
0.748 0.252 0.000
I27.2 Other secondary pulmonary hypertension
0.745 0.255 0.000
E11.2 With renal complications
0.741 0.259 0.000
A08 Viral and other specified intestinal infections
0.741 0.259 0.000
E23 Hypofunction and other disorders of pituitary gland
0.740 0.260 0.000
H55-H59 Other disorders of eye and adnexa
0.740 0.260 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.737 0.263 0.000
J30.1 Allergic rhinitis due to pollen
0.734 0.266 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.734 0.266 0.000
M65-M68 Disorders of synovium and tendon
0.733 0.267 0.000
J45 Asthma
0.731 0.269 0.000
H80-H83 Diseases of inner ear
0.730 0.270 0.000
E13 Other specified diabetes mellitus
0.730 0.270 0.000
K22.4 Dyskinesia of oesophagus
0.726 0.274 0.000
J20-J22 Other acute lower respiratory infections
0.726 0.274 0.000
H02 Other disorders of eyelid
0.726 0.274 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.725 0.275 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
K35-K38 Diseases of appendix
0.722 0.278 0.000
E28 Ovarian dysfunction
0.722 0.278 0.000
C15-C26 Malignant neoplasms of digestive organs
0.721 0.279 0.000
K05 Gingivitis and periodontal diseases
0.721 0.279 0.000
C60-C63 Malignant neoplasms of male genital organs
0.720 0.280 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.719 0.281 0.000
K22.8 Other specified diseases of oesophagus
0.719 0.281 0.000
G62.9 Polyneuropathy, unspecified
0.718 0.282 0.000
M06 Other rheumatoid arthritis
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.716 0.284 0.000
K51.8 Other ulcerative colitis
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
C67 Malignant neoplasm of bladder
0.715 0.285 0.000
K29.9 Gastroduodenitis, unspecified
0.714 0.286 0.000
K29.2 Alcoholic gastritis
0.714 0.286 0.000
K22.5 Diverticulum of oesophagus, acquired
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.713 0.287 0.000
K11 Diseases of salivary glands
0.713 0.287 0.000
K26.7 Chronic without haemorrhage or perforation
0.712 0.288 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.711 0.289 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A80-A89 Viral infections of the central nervous system
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
E83 Disorders of mineral metabolism
0.711 0.289 0.000
E11.8 With unspecified complications
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.6 With other specified complications
0.711 0.289 0.000
E11.1 With ketoacidosis
0.711 0.289 0.000
E11.0 With coma
0.711 0.289 0.000
K29.0 Acute haemorrhagic gastritis
0.708 0.292 0.000
H36.0 Diabetic retinopathy
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.706 0.294 0.000
H43 Disorders of vitreous body
0.706 0.294 0.000
K50 Crohn's disease [regional enteritis]
0.705 0.295 0.000
I30-I52 Other forms of heart disease
0.704 0.296 0.000
A07 Other protozoal intestinal diseases
0.704 0.296 0.000
A06 Amoebiasis
0.704 0.296 0.000
A05 Other bacterial foodborne intoxications
0.704 0.296 0.000
A03 Shigellosis
0.704 0.296 0.000
A02 Other Salmonella infections
0.704 0.296 0.000
A01 Typhoid and paratyphoid fevers
0.704 0.296 0.000
A00 Cholera
0.704 0.296 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.703 0.297 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.703 0.297 0.000
C92 Myeloid leukaemia
0.702 0.298 0.000
I95.2 Hypotension due to drugs
0.702 0.298 0.000
I15 Secondary hypertension
0.701 0.299 0.000
I13 Hypertensive heart and renal disease
0.701 0.299 0.000
I11 Hypertensive heart disease
0.701 0.299 0.000
J69 Pneumonitis due to solids and liquids
0.698 0.301 0.000
K22.3 Perforation of oesophagus
0.698 0.302 0.000
K22.0 Achalasia of cardia
0.698 0.302 0.000
K55-K64 Other diseases of intestines
0.698 0.302 0.000
K10 Other diseases of jaws
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.697 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
J93.1 Other spontaneous pneumothorax
0.696 0.304 0.000
J37 Chronic laryngitis and laryngotracheitis
0.694 0.306 0.000
J91 Pleural effusion in conditions classified elsewhere
0.693 0.307 0.000
M80-M85 Disorders of bone density and structure
0.693 0.307 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.692 0.307 0.000
K26.5 Chronic or unspecified with perforation
0.692 0.307 0.000
K26.2 Acute with both haemorrhage and perforation
0.692 0.307 0.000
K26.1 Acute with perforation
0.692 0.307 0.000
K26.0 Acute with haemorrhage
0.692 0.307 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.692 0.308 0.000
K57 Diverticular disease of intestine
0.690 0.310 0.000
K75 Other inflammatory liver diseases
0.690 0.310 0.000
K01 Embedded and impacted teeth
0.690 0.310 0.000
C81 Hodgkin's disease
0.690 0.310 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.689 0.311 0.000
I28 Other diseases of pulmonary vessels
0.688 0.312 0.000
H60-H62 Diseases of external ear
0.687 0.313 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.687 0.313 0.000
H25-H28 Disorders of lens
0.686 0.313 0.000
K26.4 Chronic or unspecified with haemorrhage
0.685 0.315 0.000
H53.9 Visual disturbance, unspecified
0.685 0.315 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.684 0.315 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.684 0.315 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.684 0.316 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.684 0.316 0.000
I95.1 Orthostatic hypotension
0.683 0.317 0.000
H65-H75 Diseases of middle ear and mastoid
0.682 0.318 0.000
S60-S69 Injuries to the wrist and hand
0.681 0.319 0.000
J34.2 Deviated nasal septum
0.681 0.319 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.681 0.319 0.000
H31 Other disorders of choroid
0.681 0.319 0.000
H30 Chorioretinal inflammation
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.681 0.319 0.000
H53.2 Diplopia
0.680 0.320 0.000
J33 Nasal polyp
0.678 0.322 0.000
K52.3 Indeterminate colitis
0.677 0.323 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.677 0.323 0.000
K52.1 Toxic gastro-enteritis and colitis
0.677 0.323 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.677 0.323 0.000
A04.5 Campylobacter enteritis
0.675 0.325 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.674 0.326 0.000
D55-D59 Haemolytic anaemias
0.673 0.327 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.672 0.327 0.000
H10 Conjunctivitis
0.672 0.327 0.000
K31.5 Obstruction of duodenum
0.672 0.328 0.000
H42 Glaucoma in diseases classified elsewhere
0.671 0.329 0.000
D75.1 Secondary polycythaemia
0.669 0.331 0.000
E14.3 With ophthalmic complications
0.669 0.331 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.668 0.331 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.668 0.331 0.000
D70 Agranulocytosis
0.668 0.332 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.667 0.333 0.000
I99 Other and unspecified disorders of circulatory system
0.667 0.333 0.000
E85 Amyloidosis
0.667 0.333 0.000
E84 Cystic fibrosis
0.667 0.333 0.000
E79 Disorders of purine and pyrimidine metabolism
0.667 0.333 0.000
E77 Disorders of glycoprotein metabolism
0.667 0.333 0.000
E76 Disorders of glycosaminoglycan metabolism
0.667 0.333 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.667 0.333 0.000
E74 Other disorders of carbohydrate metabolism
0.667 0.333 0.000
E73 Lactose intolerance
0.667 0.333 0.000
E72 Other disorders of amino-acid metabolism
0.667 0.333 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.667 0.333 0.000
E70 Disorders of aromatic amino-acid metabolism
0.667 0.333 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.667 0.333 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.666 0.334 0.000
S70-S79 Injuries to the hip and thigh
0.665 0.335 0.000
J35 Chronic diseases of tonsils and adenoids
0.664 0.336 0.000
D69 Purpura and other haemorrhagic conditions
0.664 0.336 0.000
E88 Other metabolic disorders
0.664 0.336 0.000
C44 Other malignant neoplasms of skin
0.664 0.336 0.000
M06.0 Seronegative rheumatoid arthritis
0.663 0.337 0.000
H40.9 Glaucoma, unspecified
0.662 0.338 0.000
K25.7 Chronic without haemorrhage or perforation
0.660 0.340 0.000
I60-I69 Cerebrovascular diseases
0.659 0.341 0.000
K26.3 Acute without haemorrhage or perforation
0.658 0.342 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.657 0.343 0.000
K00 Disorders of tooth development and eruption
0.657 0.343 0.000
H33.5 Other retinal detachments
0.656 0.343 0.000
H33.4 Traction detachment of retina
0.656 0.343 0.000
E00-E07 Disorders of thyroid gland
0.655 0.344 0.000
B35-B49 Mycoses
0.653 0.346 0.000
D80-D89 Certain disorders involving the immune mechanism
0.653 0.347 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.653 0.347 0.000
H54 Blindness and low vision
0.652 0.348 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.651 0.349 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.651 0.349 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.651 0.349 0.000
D00-D09 In situ neoplasms
0.651 0.349 0.000
S51 Open wound of forearm
0.650 0.350 0.000
J03 Acute tonsillitis
0.649 0.351 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.649 0.351 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.649 0.351 0.000
E34 Other endocrine disorders
0.649 0.351 0.000
E32 Diseases of thymus
0.649 0.351 0.000
E31 Polyglandular dysfunction
0.649 0.351 0.000
E30 Disorders of puberty, not elsewhere classified
0.649 0.351 0.000
E29 Testicular dysfunction
0.649 0.351 0.000
E26 Hyperaldosteronism
0.649 0.351 0.000
E25 Adrenogenital disorders
0.649 0.351 0.000
E24 Cushing's syndrome
0.649 0.351 0.000
E22 Hyperfunction of pituitary gland
0.649 0.351 0.000
E20 Hypoparathyroidism
0.649 0.351 0.000
C44.3 Skin of other and unspecified parts of face
0.648 0.352 0.000
S20-S29 Injuries to the thorax
0.648 0.352 0.000
F99-F99 Unspecified mental disorder
0.647 0.353 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.647 0.353 0.000
F70-F79 Mental retardation
0.647 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.647 0.353 0.000
J30.3 Other allergic rhinitis
0.646 0.354 0.000
I27.9 Pulmonary heart disease, unspecified
0.645 0.354 0.000
J98 Other respiratory disorders
0.645 0.355 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.645 0.355 0.000
J41 Simple and mucopurulent chronic bronchitis
0.645 0.355 0.000
J92 Pleural plaque
0.644 0.356 0.000
A04.8 Other specified bacterial intestinal infections
0.644 0.356 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.644 0.356 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.644 0.356 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.644 0.356 0.000
H90-H95 Other disorders of ear
0.643 0.357 0.000
M40-M43 Deforming dorsopathies
0.643 0.357 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.642 0.358 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.642 0.358 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.641 0.359 0.000
H11.9 Disorder of conjunctiva, unspecified
0.641 0.359 0.000
H11.3 Conjunctival haemorrhage
0.641 0.359 0.000
H11.2 Conjunctival scars
0.641 0.359 0.000
H11.1 Conjunctival degenerations and deposits
0.641 0.359 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.640 0.360 0.000
T90 Sequelae of injuries of head
0.640 0.360 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.640 0.360 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.639 0.360 0.000
Chapter XX External causes of morbidity and mortality
0.639 0.361 0.000
K29.6 Other gastritis
0.638 0.362 0.000
H40.8 Other glaucoma
0.638 0.362 0.000
H40.6 Glaucoma secondary to drugs
0.638 0.362 0.000
H40.5 Glaucoma secondary to other eye disorders
0.638 0.362 0.000
H40.4 Glaucoma secondary to eye inflammation
0.638 0.362 0.000
H40.3 Glaucoma secondary to eye trauma
0.638 0.362 0.000
F31.9 Bipolar affective disorder, unspecified
0.638 0.362 0.000
K22.9 Disease of oesophagus, unspecified
0.636 0.364 0.000
I95.8 Other hypotension
0.636 0.364 0.000
I95.0 Idiopathic hypotension
0.636 0.364 0.000
H02.8 Other specified disorders of eyelid
0.635 0.365 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.635 0.365 0.000
B18 Chronic viral hepatitis
0.634 0.366 0.000
B17 Other acute viral hepatitis
0.633 0.367 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.633 0.367 0.000
E63 Other nutritional deficiencies
0.633 0.367 0.000
E61 Deficiency of other nutrient elements
0.633 0.367 0.000
E56 Other vitamin deficiencies
0.633 0.367 0.000
E51 Thiamine deficiency
0.633 0.367 0.000
E50 Vitamin A deficiency
0.633 0.367 0.000
E60 Dietary zinc deficiency
0.633 0.367 0.000
E59 Dietary selenium deficiency
0.633 0.367 0.000
E58 Dietary calcium deficiency
0.633 0.367 0.000
E54 Ascorbic acid deficiency
0.633 0.367 0.000
E52 Niacin deficiency [pellagra]
0.633 0.367 0.000
J32.9 Chronic sinusitis, unspecified
0.633 0.367 0.000
D45 Polycythaemia vera
0.632 0.368 0.000
T79-T79 Certain early complications of trauma
0.630 0.370 0.000
H02.9 Disorder of eyelid, unspecified
0.630 0.370 0.000
D62 Acute posthaemorrhagic anaemia
0.630 0.370 0.000
I12.9 Hypertensive renal disease without renal failure
0.629 0.371 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.629 0.371 0.000
K25.5 Chronic or unspecified with perforation
0.629 0.371 0.000
K25.4 Chronic or unspecified with haemorrhage
0.629 0.371 0.000
K25.2 Acute with both haemorrhage and perforation
0.629 0.371 0.000
K25.1 Acute with perforation
0.629 0.371 0.000
K25.0 Acute with haemorrhage
0.629 0.371 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.629 0.371 0.000
G62.0 Drug-induced polyneuropathy
0.629 0.371 0.000
I50 Heart failure
0.629 0.371 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.628 0.372 0.000
D72 Other disorders of white blood cells
0.628 0.372 0.000
E14.9 Without complications
0.628 0.372 0.000
H50 Other strabismus
0.627 0.373 0.000
H80 Otosclerosis
0.626 0.374 0.000
K31.6 Fistula of stomach and duodenum
0.625 0.374 0.000
K31.4 Gastric diverticulum
0.625 0.374 0.000
K31.3 Pylorospasm, not elsewhere classified
0.625 0.374 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.625 0.374 0.000
K31.0 Acute dilatation of stomach
0.625 0.374 0.000
J42 Unspecified chronic bronchitis
0.624 0.376 0.000
J39 Other diseases of upper respiratory tract
0.624 0.376 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.624 0.376 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.623 0.377 0.000
E23.0 Hypopituitarism
0.622 0.377 0.000
J84 Other interstitial pulmonary diseases
0.622 0.378 0.000
B95-B98 Bacterial, viral and other infectious agents
0.622 0.378 0.000
K05.3 Chronic periodontitis
0.620 0.380 0.000
K02 Dental caries
0.620 0.380 0.000
L08 Other local infections of skin and subcutaneous tissue
0.620 0.380 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.620 0.380 0.000
E27.9 Disorder of adrenal gland, unspecified
0.619 0.381 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.619 0.381 0.000
D74 Methaemoglobinaemia
0.619 0.381 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.619 0.381 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.619 0.381 0.000
K12 Stomatitis and related lesions
0.619 0.381 0.000
D64 Other anaemias
0.618 0.382 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.617 0.383 0.000
E78.8 Other disorders of lipoprotein metabolism
0.617 0.383 0.000
E78.6 Lipoprotein deficiency
0.617 0.383 0.000
E78.4 Other hyperlipidaemia
0.617 0.383 0.000
E78.3 Hyperchylomicronaemia
0.617 0.383 0.000
E78.2 Mixed hyperlipidaemia
0.617 0.383 0.000
E78.1 Pure hyperglyceridaemia
0.617 0.383 0.000
K09 Cysts of oral region, not elsewhere classified
0.617 0.383 0.000
K03 Other diseases of hard tissues of teeth
0.617 0.383 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.617 0.383 0.000
F38 Other mood [affective] disorders
0.616 0.383 0.000
F34 Persistent mood [affective] disorders
0.616 0.383 0.000
F30 Manic episode
0.616 0.383 0.000
F39 Unspecified mood [affective] disorder
0.616 0.383 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.616 0.384 0.000
B06 Rubella [German measles]
0.616 0.384 0.000
B05 Measles
0.616 0.384 0.000
B01 Varicella [chickenpox]
0.616 0.384 0.000
B00 Herpesviral [herpes simplex] infections
0.616 0.384 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.616 0.384 0.000
B04 Monkeypox
0.616 0.384 0.000
B03 Smallpox
0.616 0.384 0.000
M05 Seropositive rheumatoid arthritis
0.615 0.385 0.000
E65-E68 Obesity and other hyperalimentation
0.613 0.387 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.612 0.388 0.000
T33-T35 Frostbite
0.611 0.389 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.611 0.389 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.611 0.389 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.611 0.389 0.000
T00-T07 Injuries involving multiple body regions
0.611 0.389 0.000
S10-S19 Injuries to the neck
0.611 0.389 0.000
M65 Synovitis and tenosynovitis
0.610 0.390 0.000
M86 Osteomyelitis
0.610 0.390 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.609 0.391 0.000
J69.0 Pneumonitis due to food and vomit
0.609 0.391 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.607 0.393 0.000
K92 Other diseases of digestive system
0.607 0.393 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.607 0.393 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.606 0.394 0.000
C95 Leukaemia of unspecified cell type
0.606 0.394 0.000
C94 Other leukaemias of specified cell type
0.606 0.394 0.000
C93 Monocytic leukaemia
0.606 0.394 0.000
C88 Malignant immunoproliferative diseases
0.606 0.394 0.000
C86 Other specified types of T/NK-cell lymphoma
0.606 0.394 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.606 0.394 0.000
C43 Malignant melanoma of skin
0.606 0.394 0.000
K27 Peptic ulcer, site unspecified
0.605 0.395 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.605 0.395 0.000
I27.8 Other specified pulmonary heart diseases
0.604 0.395 0.000
I27.1 Kyphoscoliotic heart disease
0.604 0.395 0.000
M91-M94 Chondropathies
0.604 0.396 0.000
M60-M63 Disorders of muscles
0.604 0.396 0.000
M00-M03 Infectious arthropathies
0.604 0.396 0.000
J30.4 Allergic rhinitis, unspecified
0.604 0.396 0.000
J30.2 Other seasonal allergic rhinitis
0.604 0.396 0.000
J30.0 Vasomotor rhinitis
0.604 0.396 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.604 0.396 0.000
I34 Nonrheumatic mitral valve disorders
0.603 0.396 0.000
H44 Disorders of globe
0.603 0.397 0.000
G61 Inflammatory polyneuropathy
0.603 0.397 0.000
I08 Multiple valve diseases
0.603 0.397 0.000
D73 Diseases of spleen
0.602 0.397 0.000
K14 Diseases of tongue
0.601 0.399 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.601 0.399 0.000
M67 Other disorders of synovium and tendon
0.601 0.399 0.000
A04.9 Bacterial intestinal infection, unspecified
0.600 0.400 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.600 0.400 0.000
A04.4 Other intestinal Escherichia coli infections
0.600 0.400 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.600 0.400 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.600 0.400 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.600 0.400 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.600 0.400 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.600 0.400 0.000
C92.0 Acute myeloid leukaemia
0.600 0.400 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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