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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114718455
log Bayes Factor = 13.0267
Chromosome 3   position 53,464,055  (GRCh37) Explore rs114718455 on Ensembl!
Variant rs114718455 is part of Cluster X0249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter II Neoplasms
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.992 0.008 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.991 0.009 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.990 0.010 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.978 0.022 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.974 0.026 0.000
O60-O75 Complications of labour and delivery
0.972 0.028 0.000
I30-I52 Other forms of heart disease
0.971 0.029 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.971 0.029 0.000
I05-I09 Chronic rheumatic heart diseases
0.970 0.030 0.000
Chapter X Diseases of the respiratory system
0.970 0.030 0.000
I84 Haemorrhoids
0.970 0.030 0.000
R06 Abnormalities of breathing
0.967 0.033 0.000
I50 Heart failure
0.958 0.042 0.000
M40-M43 Deforming dorsopathies
0.954 0.046 0.000
R07 Pain in throat and chest
0.953 0.047 0.000
J09-J18 Influenza and pneumonia
0.947 0.053 0.000
R73 Elevated blood glucose level
0.947 0.053 0.000
M45-M49 Spondylopathies
0.946 0.054 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.946 0.054 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.944 0.056 0.000
I50.0 Congestive heart failure
0.942 0.058 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.941 0.059 0.000
C77.3 Axillary and upper limb lymph nodes
0.937 0.063 0.000
M43 Other deforming dorsopathies
0.937 0.063 0.000
R01 Cardiac murmurs and other cardiac sounds
0.935 0.065 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.931 0.069 0.000
C77.1 Intrathoracic lymph nodes
0.928 0.072 0.000
I84.6 Residual haemorrhoidal skin tags
0.927 0.073 0.000
Chapter I Certain infectious and parasitic diseases
0.926 0.074 0.000
R06.8 Other and unspecified abnormalities of breathing
0.924 0.076 0.000
M43.1 Spondylolisthesis
0.922 0.078 0.000
I27 Other pulmonary heart diseases
0.920 0.080 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.915 0.085 0.000
R47-R49 Symptoms and signs involving speech and voice
0.915 0.085 0.000
C77.2 Intra-abdominal lymph nodes
0.914 0.086 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.913 0.087 0.000
I60-I69 Cerebrovascular diseases
0.913 0.087 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.912 0.088 0.000
R79 Other abnormal findings of blood chemistry
0.910 0.090 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.908 0.092 0.000
I08 Multiple valve diseases
0.908 0.092 0.000
I84.2 Internal haemorrhoids without complication
0.906 0.094 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.901 0.099 0.000
R01.1 Cardiac murmur, unspecified
0.900 0.100 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.897 0.103 0.000
C78.2 Secondary malignant neoplasm of pleura
0.895 0.105 0.000
I45 Other conduction disorders
0.892 0.108 0.000
I20-I25 Ischaemic heart diseases
0.891 0.109 0.000
J20-J22 Other acute lower respiratory infections
0.887 0.113 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.887 0.113 0.000
J90-J94 Other diseases of pleura
0.887 0.113 0.000
J18 Pneumonia, organism unspecified
0.882 0.118 0.000
R42 Dizziness and giddiness
0.881 0.119 0.000
C78.0 Secondary malignant neoplasm of lung
0.879 0.121 0.000
I27.2 Other secondary pulmonary hypertension
0.878 0.122 0.000
O63 Long labour
0.876 0.124 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.874 0.126 0.000
I20 Angina pectoris
0.871 0.129 0.000
R73.0 Abnormal glucose tolerance test
0.870 0.130 0.000
M47 Spondylosis
0.870 0.130 0.000
I61 Intracerebral haemorrhage
0.867 0.133 0.000
R07.2 Precordial pain
0.865 0.135 0.000
I50.9 Heart failure, unspecified
0.864 0.136 0.000
I84.3 External thrombosed haemorrhoids
0.864 0.136 0.000
R47 Speech disturbances, not elsewhere classified
0.863 0.137 0.000
I45.1 Other and unspecified right bundle-branch block
0.863 0.137 0.000
I82 Other venous embolism and thrombosis
0.862 0.138 0.000
D70 Agranulocytosis
0.860 0.140 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.858 0.142 0.000
J18.1 Lobar pneumonia, unspecified
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.857 0.143 0.000
R06.0 Dyspnoea
0.854 0.146 0.000
I51 Complications and ill-defined descriptions of heart disease
0.853 0.147 0.000
I20.9 Angina pectoris, unspecified
0.853 0.147 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.851 0.149 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.849 0.151 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.847 0.153 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.846 0.154 0.000
O47 False labour
0.845 0.155 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.843 0.157 0.000
R73.9 Hyperglycaemia, unspecified
0.841 0.159 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.840 0.160 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.839 0.161 0.000
I07 Rheumatic tricuspid valve diseases
0.839 0.161 0.000
M60-M63 Disorders of muscles
0.839 0.161 0.000
W00-W19 Falls
0.838 0.162 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.833 0.167 0.000
C15-C26 Malignant neoplasms of digestive organs
0.831 0.169 0.000
B35-B49 Mycoses
0.830 0.170 0.000
Y48 Anaesthetics and therapeutic gases
0.829 0.171 0.000
J90 Pleural effusion, not elsewhere classified
0.828 0.172 0.000
J22 Unspecified acute lower respiratory infection
0.827 0.173 0.000
M48 Other spondylopathies
0.827 0.173 0.000
R07.3 Other chest pain
0.825 0.175 0.000
R07.0 Pain in throat
0.825 0.175 0.000
Y43 Primarily systemic agents
0.819 0.181 0.000
O20 Haemorrhage in early pregnancy
0.819 0.181 0.000
A00-A09 Intestinal infectious diseases
0.816 0.184 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.814 0.186 0.000
O85-O92 Complications predominantly related to the puerperium
0.813 0.187 0.000
R04 Haemorrhage from respiratory passages
0.812 0.188 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.811 0.189 0.000
C64-C68 Malignant neoplasms of urinary tract
0.811 0.189 0.000
M91-M94 Chondropathies
0.809 0.191 0.000
R82 Other abnormal findings in urine
0.809 0.191 0.000
I84.1 Internal haemorrhoids with other complications
0.808 0.192 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.808 0.192 0.000
M80-M85 Disorders of bone density and structure
0.807 0.193 0.000
I84.8 Unspecified haemorrhoids with other complications
0.807 0.193 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.803 0.197 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.797 0.203 0.000
C77.9 Lymph node, unspecified
0.795 0.205 0.000
I84.9 Unspecified haemorrhoids without complication
0.794 0.206 0.000
D50-D53 Nutritional anaemias
0.794 0.206 0.000
C80 Malignant neoplasm without specification of site
0.794 0.206 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.793 0.207 0.000
M45 Ankylosing spondylitis
0.792 0.208 0.000
Y57 Other and unspecified drugs and medicaments
0.790 0.210 0.000
R06.4 Hyperventilation
0.787 0.213 0.000
O24 Diabetes mellitus in pregnancy
0.786 0.214 0.000
X50-X57 Overexertion, travel and privation
0.786 0.214 0.000
C73 Malignant neoplasm of thyroid gland
0.785 0.215 0.000
M47.8 Other spondylosis
0.784 0.216 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.783 0.217 0.000
R81 Glycosuria
0.783 0.217 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.782 0.218 0.000
R47.1 Dysarthria and anarthria
0.782 0.218 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.781 0.219 0.000
R07.1 Chest pain on breathing
0.781 0.219 0.000
I05 Rheumatic mitral valve diseases
0.778 0.222 0.000
R06.6 Hiccough
0.775 0.225 0.000
W20-W49 Exposure to inanimate mechanical forces
0.775 0.225 0.000
O16 Unspecified maternal hypertension
0.774 0.226 0.000
O20.0 Threatened abortion
0.773 0.227 0.000
I60 Subarachnoid haemorrhage
0.771 0.229 0.000
O63.0 Prolonged first stage (of labour)
0.771 0.229 0.000
I27.9 Pulmonary heart disease, unspecified
0.771 0.229 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.770 0.230 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.768 0.232 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.767 0.233 0.000
C78.7 Secondary malignant neoplasm of liver
0.765 0.235 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.764 0.236 0.000
C18 Malignant neoplasm of colon
0.764 0.236 0.000
R74 Abnormal serum enzyme levels
0.762 0.238 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.761 0.239 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.760 0.240 0.000
Y52 Agents primarily affecting the cardiovascular system
0.759 0.241 0.000
R04.0 Epistaxis
0.759 0.241 0.000
I82.2 Embolism and thrombosis of vena cava
0.757 0.243 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.756 0.244 0.000
X20-X29 Contact with venomous animals and plants
0.755 0.245 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.755 0.245 0.000
M86-M90 Other osteopathies
0.754 0.245 0.000
O80-O84 Delivery
0.754 0.246 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.754 0.246 0.000
R06.2 Wheezing
0.753 0.247 0.000
R47.8 Other and unspecified speech disturbances
0.752 0.248 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.750 0.250 0.000
I47 Paroxysmal tachycardia
0.749 0.251 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.748 0.252 0.000
O21 Excessive vomiting in pregnancy
0.748 0.252 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.748 0.252 0.000
I69 Sequelae of cerebrovascular disease
0.747 0.253 0.000
A04 Other bacterial intestinal infections
0.746 0.254 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.746 0.254 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.746 0.254 0.000
I07.1 Tricuspid insufficiency
0.744 0.256 0.000
I08.0 Disorders of both mitral and aortic valves
0.743 0.257 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.740 0.260 0.000
R46 Symptoms and signs involving appearance and behaviour
0.739 0.261 0.000
M62 Other disorders of muscle
0.739 0.261 0.000
I27.0 Primary pulmonary hypertension
0.739 0.261 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.738 0.262 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.737 0.263 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.736 0.264 0.000
O41 Other disorders of amniotic fluid and membranes
0.736 0.264 0.000
B25-B34 Other viral diseases
0.736 0.264 0.000
Y40 Systemic antibiotics
0.735 0.265 0.000
I44 Atrioventricular and left bundle-branch block
0.735 0.265 0.000
O47.9 False labour, unspecified
0.734 0.266 0.000
O44 Placenta praevia
0.733 0.267 0.000
C88 Malignant immunoproliferative diseases
0.733 0.267 0.000
R77 Other abnormalities of plasma proteins
0.733 0.267 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.732 0.268 0.000
I11 Hypertensive heart disease
0.729 0.271 0.000
Y48.3 Local anaesthetics
0.728 0.272 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.728 0.272 0.000
M43.0 Spondylolysis
0.726 0.274 0.000
J15.2 Pneumonia due to staphylococcus
0.726 0.274 0.000
J91 Pleural effusion in conditions classified elsewhere
0.724 0.276 0.000
C81 Hodgkin's disease
0.724 0.276 0.000
R79.0 Abnormal level of blood mineral
0.723 0.277 0.000
M47.82 Other spondylosis (Cervical region)
0.723 0.277 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.720 0.280 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.720 0.280 0.000
D52 Folate deficiency anaemia
0.719 0.281 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.719 0.281 0.000
O42 Premature rupture of membranes
0.718 0.282 0.000
C77.8 Lymph nodes of multiple regions
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I15 Secondary hypertension
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
I51.9 Heart disease, unspecified
0.717 0.283 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
J00-J06 Acute upper respiratory infections
0.714 0.286 0.000
I51.8 Other ill-defined heart diseases
0.714 0.286 0.000
B37 Candidiasis
0.713 0.287 0.000
C77.5 Intrapelvic lymph nodes
0.713 0.287 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.713 0.287 0.000
I30 Acute pericarditis
0.712 0.288 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.710 0.289 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.710 0.289 0.000
I20.8 Other forms of angina pectoris
0.710 0.290 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.710 0.290 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.710 0.290 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.710 0.290 0.000
R71 Abnormality of red blood cells
0.710 0.290 0.000
A30-A49 Other bacterial diseases
0.709 0.291 0.000
C60-C63 Malignant neoplasms of male genital organs
0.709 0.291 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.708 0.292 0.000
C91 Lymphoid leukaemia
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
C18.7 Sigmoid colon
0.705 0.295 0.000
I67 Other cerebrovascular diseases
0.705 0.295 0.000
R87 Abnormal findings in specimens from female genital organs
0.704 0.296 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.703 0.297 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.701 0.299 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.700 0.300 0.000
W07 Fall involving chair
0.700 0.300 0.000
O73 Retained placenta and membranes, without haemorrhage
0.699 0.301 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.698 0.302 0.000
I88 Nonspecific lymphadenitis
0.698 0.302 0.000
D75 Other diseases of blood and blood-forming organs
0.698 0.302 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.697 0.303 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
O74 Complications of anaesthesia during labour and delivery
0.697 0.303 0.000
O71 Other obstetric trauma
0.697 0.303 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.697 0.303 0.000
O60 Preterm delivery
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.696 0.304 0.000
I48 Atrial fibrillation and flutter
0.696 0.304 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.696 0.304 0.000
I42 Cardiomyopathy
0.696 0.304 0.000
I41 Myocarditis in diseases classified elsewhere
0.696 0.304 0.000
I40 Acute myocarditis
0.696 0.304 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.696 0.304 0.000
I37 Pulmonary valve disorders
0.696 0.304 0.000
I36 Nonrheumatic tricuspid valve disorders
0.696 0.304 0.000
I32 Pericarditis in diseases classified elsewhere
0.696 0.304 0.000
M48.0 Spinal stenosis
0.696 0.304 0.000
I44.2 Atrioventricular block, complete
0.696 0.304 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.696 0.304 0.000
Y58 Bacterial vaccines
0.696 0.304 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.696 0.304 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.696 0.304 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.696 0.304 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.696 0.304 0.000
I09 Other rheumatic heart diseases
0.696 0.304 0.000
I06 Rheumatic aortic valve diseases
0.696 0.304 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.694 0.306 0.000
O23 Infections of genito-urinary tract in pregnancy
0.694 0.306 0.000
R06.7 Sneezing
0.693 0.306 0.000
R06.3 Periodic breathing
0.693 0.306 0.000
R06.1 Stridor
0.693 0.306 0.000
M41 Scoliosis
0.693 0.307 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
V10-V19 Pedal cyclist injured in transport accident
0.692 0.308 0.000
C77.0 Lymph nodes of head, face and neck
0.690 0.310 0.000
M47.2 Other spondylosis with radiculopathy
0.689 0.311 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.689 0.311 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.689 0.311 0.000
B35 Dermatophytosis
0.688 0.311 0.000
C65 Malignant neoplasm of renal pelvis
0.686 0.314 0.000
O86 Other puerperal infections
0.686 0.314 0.000
C92 Myeloid leukaemia
0.685 0.315 0.000
M42 Spinal osteochondrosis
0.684 0.316 0.000
M40 Kyphosis and lordosis
0.684 0.316 0.000
M47.1 Other spondylosis with myelopathy
0.683 0.317 0.000
V80-V89 Other land transport accidents
0.683 0.317 0.000
O69.8 Labour and delivery complicated by other cord complications
0.682 0.318 0.000
Y43.3 Other antineoplastic drugs
0.681 0.319 0.000
I20.0 Unstable angina
0.681 0.319 0.000
O43 Placental disorders
0.680 0.320 0.000
I85 Oesophageal varices
0.679 0.321 0.000
J17 Pneumonia in diseases classified elsewhere
0.679 0.321 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.679 0.321 0.000
J12 Viral pneumonia, not elsewhere classified
0.679 0.321 0.000
J10 Influenza due to identified influenza virus
0.679 0.321 0.000
J09 Influenza due to certain identified influenza virus
0.679 0.321 0.000
M80 Osteoporosis with pathological fracture
0.679 0.321 0.000
M49 Spondylopathies in diseases classified elsewhere
0.679 0.321 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.678 0.322 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.678 0.322 0.000
C95 Leukaemia of unspecified cell type
0.678 0.322 0.000
C94 Other leukaemias of specified cell type
0.678 0.322 0.000
C93 Monocytic leukaemia
0.678 0.322 0.000
C86 Other specified types of T/NK-cell lymphoma
0.678 0.322 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.678 0.322 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.677 0.323 0.000
O63.1 Prolonged second stage (of labour)
0.677 0.323 0.000
O63.9 Long labour, unspecified
0.677 0.323 0.000
I28 Other diseases of pulmonary vessels
0.676 0.323 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.675 0.325 0.000
D55-D59 Haemolytic anaemias
0.674 0.326 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.674 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.674 0.326 0.000
J86 Pyothorax
0.674 0.326 0.000
I82.8 Embolism and thrombosis of other specified veins
0.673 0.327 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.673 0.327 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.672 0.328 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
M43.9 Deforming dorsopathy, unspecified
0.672 0.328 0.000
M43.8 Other specified deforming dorsopathies
0.672 0.328 0.000
M43.6 Torticollis
0.672 0.328 0.000
M43.5 Other recurrent vertebral subluxation
0.672 0.328 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.672 0.328 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.672 0.328 0.000
M43.2 Other fusion of spine
0.672 0.328 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.671 0.329 0.000
C51-C58 Malignant neoplasms of female genital organs
0.671 0.329 0.000
R82.4 Acetonuria
0.671 0.329 0.000
I81 Portal vein thrombosis
0.671 0.329 0.000
R01.2 Other cardiac sounds
0.670 0.330 0.000
C23 Malignant neoplasm of gallbladder
0.670 0.330 0.000
O62 Abnormalities of forces of labour
0.669 0.330 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.669 0.331 0.000
C18.9 Colon, unspecified
0.668 0.332 0.000
J11 Influenza, virus not identified
0.668 0.332 0.000
O29 Complications of anaesthesia during pregnancy
0.668 0.332 0.000
O28 Abnormal findings on antenatal screening of mother
0.668 0.332 0.000
O22 Venous complications in pregnancy
0.668 0.332 0.000
O25 Malnutrition in pregnancy
0.668 0.332 0.000
M62.8 Other specified disorders of muscle
0.668 0.332 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.667 0.333 0.000
I34 Nonrheumatic mitral valve disorders
0.666 0.334 0.000
D52.9 Folate deficiency anaemia, unspecified
0.666 0.334 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.665 0.335 0.000
O61 Failed induction of labour
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.664 0.335 0.000
I08.8 Other multiple valve diseases
0.664 0.336 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.664 0.336 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.664 0.336 0.000
B65-B83 Helminthiases
0.664 0.336 0.000
B50-B64 Protozoal diseases
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.664 0.336 0.000
A75-A79 Rickettsioses
0.664 0.336 0.000
A70-A74 Other diseases caused by chlamydiae
0.664 0.336 0.000
A65-A69 Other spirochaetal diseases
0.664 0.336 0.000
A20-A28 Certain zoonotic bacterial diseases
0.664 0.336 0.000
A15-A19 Tuberculosis
0.664 0.336 0.000
M50-M54 Other dorsopathies
0.661 0.338 0.000
Y57.9 Drug or medicament, unspecified
0.661 0.339 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.661 0.339 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.661 0.339 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.661 0.339 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.661 0.339 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.661 0.339 0.000
M43.12 Spondylolisthesis (Cervical region)
0.661 0.339 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.661 0.339 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.661 0.339 0.000
O30 Multiple gestation
0.660 0.340 0.000
I27.8 Other specified pulmonary heart diseases
0.660 0.340 0.000
I27.1 Kyphoscoliotic heart disease
0.660 0.340 0.000
C85.1 B-cell lymphoma, unspecified
0.659 0.341 0.000
I45.3 Trifascicular block
0.659 0.341 0.000
J14 Pneumonia due to Haemophilus influenzae
0.659 0.341 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.658 0.342 0.000
B99-B99 Other infectious diseases
0.657 0.342 0.000
O45 Premature separation of placenta [abruptio placentae]
0.656 0.344 0.000
O33 Maternal care for known or suspected disproportion
0.656 0.344 0.000
O31 Complications specific to multiple gestation
0.656 0.344 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.656 0.344 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.656 0.344 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.654 0.346 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.654 0.346 0.000
O15 Eclampsia
0.654 0.346 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.654 0.346 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.654 0.346 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.653 0.347 0.000
Y40.9 Systemic antibiotic, unspecified
0.651 0.349 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.651 0.349 0.000
R43 Disturbances of smell and taste
0.651 0.349 0.000
O82 Single delivery by Caesarean section
0.651 0.349 0.000
I08.9 Multiple valve disease, unspecified
0.651 0.349 0.000
I24 Other acute ischaemic heart diseases
0.651 0.349 0.000
M92 Other juvenile osteochondrosis
0.650 0.350 0.000
J95-J99 Other diseases of the respiratory system
0.649 0.351 0.000
W06 Fall involving bed
0.649 0.351 0.000
O47.0 False labour before 37 completed weeks of gestation
0.649 0.351 0.000
D73 Diseases of spleen
0.648 0.352 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.648 0.352 0.000
O66 Other obstructed labour
0.647 0.353 0.000
I05.2 Mitral stenosis with insufficiency
0.647 0.353 0.000
I87 Other disorders of veins
0.646 0.354 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.646 0.354 0.000
C16 Malignant neoplasm of stomach
0.645 0.355 0.000
X51 Travel and motion
0.645 0.355 0.000
D74 Methaemoglobinaemia
0.643 0.357 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.643 0.357 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.643 0.357 0.000
X60-X84 Intentional self-harm
0.643 0.357 0.000
D80-D89 Certain disorders involving the immune mechanism
0.643 0.357 0.000
M46 Other inflammatory spondylopathies
0.641 0.359 0.000
I45.8 Other specified conduction disorders
0.640 0.360 0.000
I45.4 Nonspecific intraventricular block
0.640 0.360 0.000
I45.2 Bifascicular block
0.640 0.360 0.000
I45.0 Right fascicular block
0.640 0.360 0.000
W44 Foreign body entering into or through eye or natural orifice
0.640 0.360 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.639 0.361 0.000
I23 Certain current complications following acute myocardial infarction
0.639 0.361 0.000
I51.6 Cardiovascular disease, unspecified
0.638 0.362 0.000
Y42.5 Other oestrogens and progestogens
0.638 0.362 0.000
Y43.1 Antineoplastic antimetabolites
0.637 0.363 0.000
R76 Other abnormal immunological findings in serum
0.637 0.363 0.000
J15.4 Pneumonia due to other streptococci
0.637 0.363 0.000
R82.8 Abnormal findings on cytological and histological examination of urine
0.636 0.364 0.000
J21 Acute bronchiolitis
0.636 0.364 0.000
J20 Acute bronchitis
0.636 0.364 0.000
R01.0 Benign and innocent cardiac murmurs
0.635 0.365 0.000
J03 Acute tonsillitis
0.635 0.365 0.000
B15-B19 Viral hepatitis
0.634 0.365 0.000
J18.8 Other pneumonia, organism unspecified
0.632 0.368 0.000
J18.2 Hypostatic pneumonia, unspecified
0.632 0.368 0.000
I84.0 Internal thrombosed haemorrhoids
0.632 0.368 0.000
J94 Other pleural conditions
0.631 0.369 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.631 0.369 0.000
C62 Malignant neoplasm of testis
0.630 0.370 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.630 0.370 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.628 0.372 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.626 0.373 0.000
C74 Malignant neoplasm of adrenal gland
0.626 0.373 0.000
O72 Postpartum haemorrhage
0.626 0.374 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.626 0.374 0.000
Chapter XI Diseases of the digestive system
0.624 0.376 0.000
I84.4 External haemorrhoids with other complications
0.624 0.376 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.624 0.376 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.624 0.376 0.000
I45.6 Preexcitation syndrome
0.624 0.376 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.623 0.376 0.000
D60-D64 Aplastic and other anaemias
0.623 0.377 0.000
R49 Voice disturbances
0.622 0.378 0.000
C18.3 Hepatic flexure
0.622 0.378 0.000
I61.8 Other intracerebral haemorrhage
0.622 0.378 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.622 0.378 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.622 0.378 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.622 0.378 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.622 0.378 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.622 0.378 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.621 0.379 0.000
M93 Other osteochondropathies
0.620 0.380 0.000
I86 Varicose veins of other sites
0.620 0.380 0.000
Y44 Agents primarily affecting blood constituents
0.619 0.381 0.000
I82.3 Embolism and thrombosis of renal vein
0.618 0.382 0.000
I82.1 Thrombophlebitis migrans
0.618 0.382 0.000
I82.0 Budd-Chiari syndrome
0.618 0.382 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.618 0.382 0.000
C66 Malignant neoplasm of ureter
0.618 0.382 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.617 0.383 0.000
W19 Unspecified fall
0.617 0.383 0.000
W10 Fall on and from stairs and steps
0.616 0.384 0.000
I69.3 Sequelae of cerebral infarction
0.616 0.384 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.615 0.385 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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