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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114752401
log Bayes Factor = 17.2608
Chromosome 4   position 188,730,635  (GRCh37) Explore rs114752401 on Ensembl!
Variant rs114752401 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter II Neoplasms
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
E11 Non-insulin-dependent diabetes mellitus
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.988 0.012 0.000
M13 Other arthritis
0.987 0.013 0.000
Chapter XIV Diseases of the genitourinary system
0.986 0.014 0.000
G40-G47 Episodic and paroxysmal disorders
0.983 0.017 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.981 0.019 0.000
M13.9 Arthritis, unspecified
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.975 0.025 0.000
E00-E07 Disorders of thyroid gland
0.973 0.027 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.972 0.028 0.000
M15-M19 Arthrosis
0.968 0.032 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.965 0.035 0.000
M45-M49 Spondylopathies
0.964 0.036 0.000
Chapter VIII Diseases of the ear and mastoid process
0.963 0.037 0.000
M19 Other arthrosis
0.963 0.037 0.000
M19.9 Arthrosis, unspecified
0.958 0.042 0.000
G40 Epilepsy
0.957 0.043 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.954 0.046 0.000
O60-O75 Complications of labour and delivery
0.953 0.047 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.951 0.049 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.951 0.049 0.000
G40.9 Epilepsy, unspecified
0.943 0.057 0.000
H65-H75 Diseases of middle ear and mastoid
0.942 0.058 0.000
M48 Other spondylopathies
0.937 0.063 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.934 0.065 0.000
E10 Insulin-dependent diabetes mellitus
0.934 0.066 0.000
M50-M54 Other dorsopathies
0.932 0.068 0.000
N00-N08 Glomerular diseases
0.931 0.069 0.000
E11.3 With ophthalmic complications
0.923 0.077 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.920 0.080 0.000
M48.0 Spinal stenosis
0.918 0.082 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.917 0.083 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.917 0.083 0.000
M13.98 Arthritis, unspecified (Other)
0.917 0.083 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.908 0.092 0.000
N30-N39 Other diseases of urinary system
0.907 0.093 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.904 0.096 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.901 0.099 0.000
E11.4 With neurological complications
0.900 0.100 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.893 0.107 0.000
E11.6 With other specified complications
0.889 0.111 0.000
D10-D36 Benign neoplasms
0.887 0.113 0.000
E70-E90 Metabolic disorders
0.887 0.113 0.000
M40-M43 Deforming dorsopathies
0.885 0.115 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.885 0.115 0.000
C15 Malignant neoplasm of oesophagus
0.885 0.115 0.000
E04 Other non-toxic goitre
0.883 0.117 0.000
H30-H36 Disorders of choroid and retina
0.877 0.123 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.877 0.123 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.877 0.123 0.000
M20-M25 Other joint disorders
0.876 0.124 0.000
E11.2 With renal complications
0.874 0.126 0.000
M54 Dorsalgia
0.874 0.126 0.000
G90-G99 Other disorders of the nervous system
0.871 0.129 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.870 0.130 0.000
M14 Arthropathies in other diseases classified elsewhere
0.867 0.133 0.000
Q60-Q64 Congenital malformations of the urinary system
0.866 0.134 0.000
M48.06 Spinal stenosis (Lumbar region)
0.865 0.135 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.864 0.136 0.000
C25 Malignant neoplasm of pancreas
0.863 0.137 0.000
N17-N19 Renal failure
0.860 0.140 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.860 0.140 0.000
H53-H54 Visual disturbances and blindness
0.857 0.143 0.000
H72 Perforation of tympanic membrane
0.857 0.143 0.000
C16 Malignant neoplasm of stomach
0.857 0.143 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.849 0.151 0.000
N10-N16 Renal tubulo-interstitial diseases
0.848 0.152 0.000
M54.5 Low back pain
0.842 0.158 0.000
O63 Long labour
0.841 0.159 0.000
E86 Volume depletion
0.839 0.161 0.000
G43 Migraine
0.838 0.162 0.000
G63.2 Diabetic polyneuropathy
0.835 0.165 0.000
T66-T78 Other and unspecified effects of external causes
0.835 0.165 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.833 0.167 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.832 0.168 0.000
E06 Thyroiditis
0.832 0.168 0.000
M10 Gout
0.832 0.168 0.000
G57 Mononeuropathies of lower limb
0.828 0.172 0.000
E11.5 With peripheral circulatory complications
0.828 0.172 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.827 0.173 0.000
E50-E64 Other nutritional deficiencies
0.827 0.173 0.000
E04.1 Non-toxic single thyroid nodule
0.827 0.173 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.826 0.174 0.000
O66 Other obstructed labour
0.826 0.174 0.000
M48.02 Spinal stenosis (Cervical region)
0.826 0.174 0.000
M80-M85 Disorders of bone density and structure
0.824 0.176 0.000
T81 Complications of procedures, not elsewhere classified
0.822 0.178 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.820 0.180 0.000
N18 Chronic renal failure
0.819 0.181 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.817 0.183 0.000
D00-D09 In situ neoplasms
0.816 0.184 0.000
N99-N99 Other disorders of the genitourinary system
0.816 0.184 0.000
H73 Other disorders of tympanic membrane
0.816 0.184 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.815 0.185 0.000
O00-O08 Pregnancy with abortive outcome
0.814 0.186 0.000
E13 Other specified diabetes mellitus
0.814 0.186 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.814 0.186 0.000
E20-E35 Disorders of other endocrine glands
0.814 0.186 0.000
E10.4 With neurological complications
0.814 0.186 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.812 0.188 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.810 0.189 0.000
H55-H59 Other disorders of eye and adnexa
0.810 0.189 0.000
H43-H45 Disorders of vitreous body and globe
0.808 0.192 0.000
D22 Melanocytic naevi
0.805 0.195 0.000
E05.9 Thyrotoxicosis, unspecified
0.803 0.197 0.000
M70-M79 Other soft tissue disorders
0.803 0.197 0.000
H36 Retinal disorders in diseases classified elsewhere
0.800 0.200 0.000
D24 Benign neoplasm of breast
0.799 0.201 0.000
M86-M90 Other osteopathies
0.798 0.202 0.000
E10.2 With renal complications
0.796 0.204 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.795 0.205 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.795 0.205 0.000
M46 Other inflammatory spondylopathies
0.795 0.205 0.000
T82.1 Mechanical complication of cardiac electronic device
0.794 0.206 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.793 0.207 0.000
N36 Other disorders of urethra
0.793 0.207 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.792 0.208 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.792 0.208 0.000
D32 Benign neoplasm of meninges
0.792 0.208 0.000
E10.3 With ophthalmic complications
0.790 0.210 0.000
H54 Blindness and low vision
0.789 0.211 0.000
E16 Other disorders of pancreatic internal secretion
0.789 0.211 0.000
M25 Other joint disorders, not elsewhere classified
0.788 0.212 0.000
H35 Other retinal disorders
0.788 0.212 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.787 0.213 0.000
H10-H13 Disorders of conjunctiva
0.786 0.214 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.785 0.215 0.000
M41 Scoliosis
0.784 0.216 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.782 0.218 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.780 0.220 0.000
Chapter XX External causes of morbidity and mortality
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.778 0.222 0.000
C15.9 Oesophagus, unspecified
0.778 0.222 0.000
S70-S79 Injuries to the hip and thigh
0.777 0.223 0.000
M14.6 Neuropathic arthropathy
0.775 0.225 0.000
M54.59 Low back pain (Site unspecified)
0.774 0.226 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.774 0.226 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.774 0.226 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.773 0.227 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.773 0.227 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.771 0.229 0.000
N10 Acute tubulo-interstitial nephritis
0.770 0.229 0.000
C20 Malignant neoplasm of rectum
0.770 0.230 0.000
N35 Urethral stricture
0.770 0.230 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.770 0.230 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.770 0.230 0.000
N03 Chronic nephritic syndrome
0.767 0.233 0.000
H74 Other disorders of middle ear and mastoid
0.767 0.233 0.000
O63.1 Prolonged second stage (of labour)
0.766 0.234 0.000
C21 Malignant neoplasm of anus and anal canal
0.761 0.238 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.761 0.238 0.000
G93 Other disorders of brain
0.760 0.240 0.000
O48 Prolonged pregnancy
0.759 0.241 0.000
O02 Other abnormal products of conception
0.759 0.241 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
N30 Cystitis
0.758 0.242 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.757 0.243 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.757 0.243 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.755 0.244 0.000
E88 Other metabolic disorders
0.755 0.245 0.000
G44 Other headache syndromes
0.755 0.245 0.000
M21 Other acquired deformities of limbs
0.754 0.246 0.000
N02 Recurrent and persistent haematuria
0.752 0.248 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.751 0.249 0.000
G54 Nerve root and plexus disorders
0.749 0.251 0.000
T86 Failure and rejection of transplanted organs and tissues
0.749 0.251 0.000
D46 Myelodysplastic syndromes
0.747 0.252 0.000
C25.9 Pancreas, unspecified
0.746 0.253 0.000
H36.0 Diabetic retinopathy
0.745 0.255 0.000
Q63 Other congenital malformations of kidney
0.745 0.255 0.000
G43.9 Migraine, unspecified
0.745 0.255 0.000
H65 Nonsuppurative otitis media
0.744 0.256 0.000
N18.0 End-stage renal disease
0.742 0.258 0.000
O62 Abnormalities of forces of labour
0.742 0.258 0.000
M19.0 Primary arthrosis of other joints
0.742 0.258 0.000
Q80-Q89 Other congenital malformations
0.741 0.259 0.000
G50 Disorders of trigeminal nerve
0.740 0.260 0.000
M05 Seropositive rheumatoid arthritis
0.740 0.260 0.000
Chapter I Certain infectious and parasitic diseases
0.738 0.262 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.738 0.262 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.737 0.263 0.000
Q61 Cystic kidney disease
0.737 0.263 0.000
H71 Cholesteatoma of middle ear
0.736 0.264 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.736 0.264 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.735 0.265 0.000
M24 Other specific joint derangements
0.734 0.266 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.733 0.267 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.732 0.268 0.000
C15.4 Middle third of oesophagus
0.732 0.268 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.732 0.268 0.000
M45 Ankylosing spondylitis
0.731 0.268 0.000
H90-H95 Other disorders of ear
0.731 0.269 0.000
E06.3 Autoimmune thyroiditis
0.731 0.269 0.000
G57.6 Lesion of plantar nerve
0.729 0.271 0.000
N18.4 Chronic kidney disease, stage 4
0.729 0.271 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.728 0.272 0.000
M13.0 Polyarthritis, unspecified
0.727 0.273 0.000
M48.09 Spinal stenosis (Site unspecified)
0.726 0.273 0.000
C80 Malignant neoplasm without specification of site
0.726 0.273 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.726 0.274 0.000
E16.2 Hypoglycaemia, unspecified
0.726 0.274 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
M91-M94 Chondropathies
0.725 0.275 0.000
H73.8 Other specified disorders of tympanic membrane
0.725 0.275 0.000
M50 Cervical disk disorders
0.724 0.276 0.000
D37.5 Rectum
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.278 0.000
G70-G73 Diseases of myoneural junction and muscle
0.721 0.278 0.000
O02.1 Missed abortion
0.720 0.280 0.000
T78 Adverse effects, not elsewhere classified
0.719 0.281 0.000
C16.0 Cardia
0.719 0.281 0.000
S40-S49 Injuries to the shoulder and upper arm
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.284 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.715 0.285 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
N20-N23 Urolithiasis
0.714 0.286 0.000
M10.9 Gout, unspecified
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.287 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.713 0.287 0.000
N25-N29 Other disorders of kidney and ureter
0.713 0.287 0.000
D45 Polycythaemia vera
0.712 0.288 0.000
M41.9 Scoliosis, unspecified
0.712 0.288 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.711 0.289 0.000
E11.8 With unspecified complications
0.710 0.290 0.000
E11.7 With multiple complications
0.710 0.290 0.000
E11.1 With ketoacidosis
0.710 0.290 0.000
E11.0 With coma
0.710 0.290 0.000
M07 Psoriatic and enteropathic arthropathies
0.708 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.708 0.292 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.708 0.292 0.000
C17 Malignant neoplasm of small intestine
0.708 0.292 0.000
C23 Malignant neoplasm of gallbladder
0.708 0.292 0.000
M13.8 Other specified arthritis
0.707 0.293 0.000
M13.1 Monoarthritis, not elsewhere classified
0.707 0.293 0.000
N72 Inflammatory disease of cervix uteri
0.707 0.293 0.000
N05 Unspecified nephritic syndrome
0.707 0.293 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.707 0.293 0.000
G30-G32 Other degenerative diseases of the nervous system
0.706 0.294 0.000
S90-S99 Injuries to the ankle and foot
0.705 0.294 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.704 0.295 0.000
G41 Status epilepticus
0.704 0.295 0.000
O85-O92 Complications predominantly related to the puerperium
0.703 0.297 0.000
G61 Inflammatory polyneuropathy
0.703 0.297 0.000
D32.0 Cerebral meninges
0.703 0.297 0.000
D26 Other benign neoplasms of uterus
0.702 0.298 0.000
M13.93 Arthritis, unspecified (Forearm)
0.702 0.298 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.702 0.298 0.000
G37 Other demyelinating diseases of central nervous system
0.701 0.299 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.701 0.299 0.000
M84 Disorders of continuity of bone
0.700 0.300 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.699 0.301 0.000
N34 Urethritis and urethral syndrome
0.699 0.301 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.698 0.302 0.000
E00 Congenital iodine-deficiency syndrome
0.698 0.302 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.698 0.302 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.697 0.302 0.000
M06 Other rheumatoid arthritis
0.697 0.303 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.697 0.303 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.697 0.303 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.697 0.303 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.697 0.303 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.696 0.303 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.696 0.304 0.000
D04 Carcinoma in situ of skin
0.696 0.304 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.696 0.304 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.695 0.304 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.695 0.305 0.000
M11 Other crystal arthropathies
0.695 0.305 0.000
M54.56 Low back pain (Lumbar region)
0.695 0.305 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.695 0.305 0.000
Q21 Congenital malformations of cardiac septa
0.695 0.305 0.000
M15 Polyarthrosis
0.694 0.306 0.000
D37.4 Colon
0.694 0.306 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.694 0.306 0.000
M19.1 Posttraumatic arthrosis of other joints
0.693 0.307 0.000
E10.1 With ketoacidosis
0.693 0.307 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.692 0.308 0.000
G58 Other mononeuropathies
0.692 0.308 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.692 0.308 0.000
G52 Disorders of other cranial nerves
0.692 0.308 0.000
M49 Spondylopathies in diseases classified elsewhere
0.691 0.308 0.000
C16.9 Stomach, unspecified
0.691 0.309 0.000
G51 Facial nerve disorders
0.691 0.309 0.000
G62 Other polyneuropathies
0.691 0.309 0.000
M19.8 Other specified arthrosis
0.690 0.310 0.000
M19.2 Other secondary arthrosis
0.690 0.310 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.690 0.310 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.689 0.311 0.000
M54.57 Low back pain (Lumbosacral region)
0.689 0.311 0.000
Chapter XI Diseases of the digestive system
0.689 0.311 0.000
C79 Secondary malignant neoplasm of other sites
0.688 0.312 0.000
H43 Disorders of vitreous body
0.688 0.312 0.000
M19.98 Arthrosis, unspecified (Other)
0.687 0.313 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.687 0.313 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.687 0.313 0.000
G40.8 Other epilepsy
0.686 0.313 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.686 0.313 0.000
G40.5 Special epileptic syndromes
0.686 0.313 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.686 0.313 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.686 0.313 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.686 0.313 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.686 0.313 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.686 0.314 0.000
H66 Suppurative and unspecified otitis media
0.685 0.315 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.685 0.315 0.000
O80-O84 Delivery
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.684 0.316 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
Q50-Q56 Congenital malformations of genital organs
0.684 0.316 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.684 0.316 0.000
Q35-Q37 Cleft lip and cleft palate
0.684 0.316 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.684 0.316 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.684 0.316 0.000
Q00-Q07 Congenital malformations of the nervous system
0.684 0.316 0.000
O74 Complications of anaesthesia during labour and delivery
0.683 0.317 0.000
O73 Retained placenta and membranes, without haemorrhage
0.683 0.317 0.000
O71 Other obstetric trauma
0.683 0.317 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.683 0.317 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.683 0.317 0.000
O61 Failed induction of labour
0.683 0.317 0.000
O60 Preterm delivery
0.683 0.317 0.000
D48.0 Bone and articular cartilage
0.683 0.317 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.683 0.317 0.000
E13.9 Without complications
0.683 0.317 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.682 0.318 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.682 0.318 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.682 0.318 0.000
T82.3 Mechanical complication of other vascular grafts
0.682 0.318 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.682 0.318 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.682 0.318 0.000
N04 Nephrotic syndrome
0.682 0.318 0.000
E87.7 Fluid overload
0.682 0.318 0.000
M43 Other deforming dorsopathies
0.682 0.318 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.681 0.319 0.000
R07 Pain in throat and chest
0.681 0.319 0.000
S50-S59 Injuries to the elbow and forearm
0.681 0.319 0.000
E03 Other hypothyroidism
0.680 0.320 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.678 0.322 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.678 0.322 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.677 0.323 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.676 0.324 0.000
H70 Mastoiditis and related conditions
0.676 0.324 0.000
H69 Other disorders of Eustachian tube
0.676 0.324 0.000
H68 Eustachian salpingitis and obstruction
0.676 0.324 0.000
H67 Otitis media in diseases classified elsewhere
0.676 0.324 0.000
E55 Vitamin D deficiency
0.676 0.324 0.000
C25.0 Head of pancreas
0.675 0.324 0.000
G83 Other paralytic syndromes
0.675 0.325 0.000
M13.94 Arthritis, unspecified (Hand)
0.674 0.326 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.673 0.327 0.000
M48.9 Spondylopathy, unspecified
0.672 0.328 0.000
M48.8 Other specified spondylopathies
0.672 0.328 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.672 0.328 0.000
M48.4 Fatigue fracture of vertebra
0.672 0.328 0.000
M48.3 Traumatic spondylopathy
0.672 0.328 0.000
M48.2 Kissing spine
0.672 0.328 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.672 0.328 0.000
N35.9 Urethral stricture, unspecified
0.672 0.328 0.000
M65-M68 Disorders of synovium and tendon
0.671 0.329 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.670 0.329 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.670 0.330 0.000
G60 Hereditary and idiopathic neuropathy
0.670 0.330 0.000
G64 Other disorders of peripheral nervous system
0.670 0.330 0.000
E10.8 With unspecified complications
0.670 0.330 0.000
E10.7 With multiple complications
0.670 0.330 0.000
E10.6 With other specified complications
0.670 0.330 0.000
E10.5 With peripheral circulatory complications
0.670 0.330 0.000
E10.0 With coma
0.670 0.330 0.000
R06 Abnormalities of breathing
0.669 0.331 0.000
Chapter V Mental and behavioural disorders
0.669 0.331 0.000
K81 Cholecystitis
0.669 0.331 0.000
M53 Other dorsopathies, not elsewhere classified
0.668 0.331 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.668 0.332 0.000
T85.2 Mechanical complication of intraocular lens
0.667 0.332 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.667 0.333 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.667 0.333 0.000
N06 Isolated proteinuria with specified morphological lesion
0.667 0.333 0.000
N01 Rapidly progressive nephritic syndrome
0.667 0.333 0.000
N00 Acute nephritic syndrome
0.667 0.333 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.667 0.333 0.000
O72 Postpartum haemorrhage
0.667 0.333 0.000
M54.3 Sciatica
0.666 0.334 0.000
Q27 Other congenital malformations of peripheral vascular system
0.665 0.334 0.000
W00-W19 Falls
0.665 0.335 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.665 0.335 0.000
N36.8 Other specified disorders of urethra
0.664 0.336 0.000
N18.5 Chronic kidney disease, stage 5
0.663 0.337 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.663 0.337 0.000
D22.5 Melanocytic naevi of trunk
0.662 0.338 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.662 0.338 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.661 0.339 0.000
E28 Ovarian dysfunction
0.661 0.339 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.661 0.339 0.000
D03 Melanoma in situ
0.661 0.339 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.660 0.340 0.000
T81.9 Unspecified complication of procedure
0.659 0.340 0.000
E04.9 Non-toxic goitre, unspecified
0.659 0.341 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.659 0.341 0.000
C64-C68 Malignant neoplasms of urinary tract
0.659 0.341 0.000
Q63.0 Accessory kidney
0.658 0.342 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.658 0.342 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.658 0.342 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.658 0.342 0.000
M48.04 Spinal stenosis (Thoracic region)
0.658 0.342 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.658 0.342 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.658 0.342 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.658 0.342 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.657 0.343 0.000
H54.0 Blindness, both eyes
0.657 0.343 0.000
H54.9 Unspecified visual impairment (binocular)
0.657 0.343 0.000
D11 Benign neoplasm of major salivary glands
0.656 0.344 0.000
M25.8 Other specified joint disorders
0.656 0.344 0.000
R06.0 Dyspnoea
0.655 0.345 0.000
C18 Malignant neoplasm of colon
0.654 0.346 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.654 0.346 0.000
O70 Perineal laceration during delivery
0.654 0.346 0.000
M51 Other intervertebral disk disorders
0.653 0.347 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.653 0.347 0.000
G91 Hydrocephalus
0.653 0.347 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.653 0.347 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.652 0.347 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.652 0.348 0.000
D37.7 Other digestive organs
0.652 0.348 0.000
K80 Cholelithiasis
0.652 0.348 0.000
H54.4 Blindness, one eye
0.652 0.348 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.651 0.349 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.651 0.349 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.651 0.349 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.651 0.349 0.000
R07.2 Precordial pain
0.651 0.349 0.000
N03.9 Unspecified
0.650 0.350 0.000
N37 Urethral disorders in diseases classified elsewhere
0.650 0.350 0.000
N33 Bladder disorders in diseases classified elsewhere
0.650 0.350 0.000
N36.2 Urethral caruncle
0.650 0.350 0.000
H10 Conjunctivitis
0.650 0.350 0.000
E14 Unspecified diabetes mellitus
0.650 0.350 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.650 0.350 0.000
H35.5 Hereditary retinal dystrophy
0.649 0.351 0.000
D10 Benign neoplasm of mouth and pharynx
0.649 0.351 0.000
D48.1 Connective and other soft tissue
0.647 0.353 0.000
D50-D53 Nutritional anaemias
0.647 0.353 0.000
H35.6 Retinal haemorrhage
0.647 0.353 0.000
M54.4 Lumbago with sciatica
0.646 0.353 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.646 0.354 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.646 0.354 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.646 0.354 0.000
N13 Obstructive and reflux uropathy
0.645 0.355 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.643 0.357 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.642 0.358 0.000
R07.3 Other chest pain
0.642 0.358 0.000
E07 Other disorders of thyroid
0.642 0.358 0.000
T88.4 Failed or difficult intubation
0.641 0.359 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.640 0.360 0.000
H50 Other strabismus
0.640 0.360 0.000
C80.9 Malignant neoplasm, unspecified
0.639 0.361 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.638 0.361 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.637 0.363 0.000
D35.1 Parathyroid gland
0.637 0.363 0.000
H80-H83 Diseases of inner ear
0.636 0.363 0.000
M25.5 Pain in joint
0.636 0.364 0.000
D31 Benign neoplasm of eye and adnexa
0.636 0.364 0.000
D30 Benign neoplasm of urinary organs
0.636 0.364 0.000
D29 Benign neoplasm of male genital organs
0.636 0.364 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.636 0.364 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.636 0.364 0.000
D19 Benign neoplasm of mesothelial tissue
0.636 0.364 0.000
D16 Benign neoplasm of bone and articular cartilage
0.636 0.364 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.636 0.364 0.000
E85 Amyloidosis
0.636 0.364 0.000
E84 Cystic fibrosis
0.636 0.364 0.000
E79 Disorders of purine and pyrimidine metabolism
0.636 0.364 0.000
E77 Disorders of glycoprotein metabolism
0.636 0.364 0.000
E76 Disorders of glycosaminoglycan metabolism
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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