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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114850483
log Bayes Factor = 16.0626
Chromosome 3   position 5,754,763  (GRCh37) Explore rs114850483 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
I51 Complications and ill-defined descriptions of heart disease
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
J30-J39 Other diseases of upper respiratory tract
0.983 0.017 0.000
I50 Heart failure
0.981 0.019 0.000
M70-M79 Other soft tissue disorders
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
J34 Other disorders of nose and nasal sinuses
0.970 0.030 0.000
I49 Other cardiac arrhythmias
0.967 0.033 0.000
H65-H75 Diseases of middle ear and mastoid
0.961 0.039 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.955 0.045 0.000
H30-H36 Disorders of choroid and retina
0.950 0.050 0.000
E70-E90 Metabolic disorders
0.949 0.051 0.000
Chapter XIV Diseases of the genitourinary system
0.948 0.052 0.000
N30-N39 Other diseases of urinary system
0.948 0.052 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.943 0.057 0.000
I44 Atrioventricular and left bundle-branch block
0.939 0.061 0.000
I50.1 Left ventricular failure
0.937 0.063 0.000
S80-S89 Injuries to the knee and lower leg
0.937 0.063 0.000
S60-S69 Injuries to the wrist and hand
0.932 0.068 0.000
I20-I25 Ischaemic heart diseases
0.929 0.071 0.000
M72 Fibroblastic disorders
0.928 0.072 0.000
I51.9 Heart disease, unspecified
0.925 0.075 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.921 0.079 0.000
E00-E07 Disorders of thyroid gland
0.920 0.080 0.000
E10-E14 Diabetes mellitus
0.919 0.081 0.000
I51.7 Cardiomegaly
0.912 0.088 0.000
N32 Other disorders of bladder
0.911 0.089 0.000
I31 Other diseases of pericardium
0.911 0.089 0.000
I05-I09 Chronic rheumatic heart diseases
0.907 0.092 0.000
N30 Cystitis
0.903 0.097 0.000
L60-L75 Disorders of skin appendages
0.899 0.101 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.892 0.108 0.000
H36 Retinal disorders in diseases classified elsewhere
0.892 0.108 0.000
M15-M19 Arthrosis
0.890 0.110 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.887 0.113 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.883 0.117 0.000
J34.3 Hypertrophy of nasal turbinates
0.883 0.117 0.000
H72 Perforation of tympanic membrane
0.882 0.118 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.881 0.119 0.000
E11 Non-insulin-dependent diabetes mellitus
0.881 0.119 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.880 0.120 0.000
I71 Aortic aneurysm and dissection
0.879 0.121 0.000
Chapter XXI Factors influencing health status and contact with health services
0.878 0.122 0.000
I46 Cardiac arrest
0.878 0.122 0.000
I51.8 Other ill-defined heart diseases
0.877 0.123 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.877 0.123 0.000
S82 Fracture of lower leg, including ankle
0.876 0.124 0.000
M75 Shoulder lesions
0.876 0.124 0.000
H52 Disorders of refraction and accommodation
0.874 0.126 0.000
N30.8 Other cystitis
0.874 0.126 0.000
E03 Other hypothyroidism
0.873 0.127 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.869 0.131 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.867 0.133 0.000
I50.0 Congestive heart failure
0.865 0.135 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.864 0.136 0.000
I44.7 Left bundle-branch block, unspecified
0.864 0.136 0.000
J34.2 Deviated nasal septum
0.864 0.136 0.000
T81 Complications of procedures, not elsewhere classified
0.862 0.138 0.000
Chapter V Mental and behavioural disorders
0.861 0.139 0.000
I47 Paroxysmal tachycardia
0.860 0.140 0.000
H43-H45 Disorders of vitreous body and globe
0.859 0.141 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.854 0.146 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.854 0.146 0.000
T79-T79 Certain early complications of trauma
0.852 0.148 0.000
H36.0 Diabetic retinopathy
0.850 0.150 0.000
I31.3 Pericardial effusion (noninflammatory)
0.850 0.150 0.000
L72.0 Epidermal cyst
0.849 0.151 0.000
N39 Other disorders of urinary system
0.849 0.151 0.000
E11.3 With ophthalmic complications
0.848 0.152 0.000
I49.8 Other specified cardiac arrhythmias
0.846 0.154 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.842 0.158 0.000
M80-M85 Disorders of bone density and structure
0.842 0.158 0.000
Z88.0 Personal history of allergy to penicillin
0.841 0.159 0.000
H34 Retinal vascular occlusions
0.840 0.160 0.000
H65 Nonsuppurative otitis media
0.839 0.161 0.000
N39.4 Other specified urinary incontinence
0.837 0.163 0.000
M19 Other arthrosis
0.835 0.165 0.000
G50 Disorders of trigeminal nerve
0.834 0.166 0.000
I49.9 Cardiac arrhythmia, unspecified
0.834 0.166 0.000
I08 Multiple valve diseases
0.831 0.169 0.000
J00-J06 Acute upper respiratory infections
0.830 0.170 0.000
I34 Nonrheumatic mitral valve disorders
0.829 0.171 0.000
E03.9 Hypothyroidism, unspecified
0.827 0.173 0.000
S82.8 Fractures of other parts of lower leg
0.826 0.174 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.824 0.176 0.000
I42 Cardiomyopathy
0.824 0.176 0.000
J90-J94 Other diseases of pleura
0.824 0.176 0.000
H10-H13 Disorders of conjunctiva
0.821 0.179 0.000
H60-H62 Diseases of external ear
0.819 0.181 0.000
G56 Mononeuropathies of upper limb
0.819 0.181 0.000
E87.6 Hypokalaemia
0.819 0.181 0.000
M71 Other bursopathies
0.818 0.182 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.818 0.182 0.000
L72.1 Trichilemmal cyst
0.816 0.184 0.000
I77 Other disorders of arteries and arterioles
0.815 0.185 0.000
G40-G47 Episodic and paroxysmal disorders
0.815 0.185 0.000
I74 Arterial embolism and thrombosis
0.813 0.187 0.000
Chapter XI Diseases of the digestive system
0.812 0.188 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.810 0.190 0.000
G20-G26 Extrapyramidal and movement disorders
0.809 0.191 0.000
G70-G73 Diseases of myoneural junction and muscle
0.807 0.193 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.806 0.194 0.000
E86 Volume depletion
0.804 0.196 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.804 0.196 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.804 0.196 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.802 0.198 0.000
I49.5 Sick sinus syndrome
0.801 0.199 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.798 0.202 0.000
M16 Coxarthrosis [arthrosis of hip]
0.797 0.203 0.000
H90-H95 Other disorders of ear
0.797 0.203 0.000
I25 Chronic ischaemic heart disease
0.797 0.203 0.000
I33 Acute and subacute endocarditis
0.796 0.204 0.000
N32.3 Diverticulum of bladder
0.794 0.206 0.000
H71 Cholesteatoma of middle ear
0.793 0.207 0.000
M91-M94 Chondropathies
0.792 0.208 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.789 0.211 0.000
J40-J47 Chronic lower respiratory diseases
0.789 0.211 0.000
S68 Traumatic amputation of wrist and hand
0.788 0.212 0.000
J38.7 Other diseases of larynx
0.788 0.212 0.000
I44.0 Atrioventricular block, first degree
0.787 0.213 0.000
S64 Injury of nerves at wrist and hand level
0.782 0.218 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.781 0.219 0.000
N32.9 Bladder disorder, unspecified
0.781 0.219 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.780 0.220 0.000
J36 Peritonsillar abscess
0.780 0.220 0.000
H50 Other strabismus
0.780 0.220 0.000
I49.0 Ventricular fibrillation and flutter
0.779 0.221 0.000
I35 Nonrheumatic aortic valve disorders
0.779 0.221 0.000
N32.8 Other specified disorders of bladder
0.779 0.221 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.778 0.222 0.000
G57 Mononeuropathies of lower limb
0.777 0.223 0.000
I22 Subsequent myocardial infarction
0.777 0.223 0.000
H69 Other disorders of Eustachian tube
0.776 0.224 0.000
Chapter XXII Codes for special purposes
0.776 0.224 0.000
H80-H83 Diseases of inner ear
0.776 0.224 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.776 0.224 0.000
I70 Atherosclerosis
0.775 0.225 0.000
M19.0 Primary arthrosis of other joints
0.774 0.226 0.000
G54 Nerve root and plexus disorders
0.773 0.227 0.000
M75.4 Impingement syndrome of shoulder
0.772 0.228 0.000
H52.0 Hypermetropia
0.770 0.230 0.000
K70-K77 Diseases of liver
0.769 0.231 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.769 0.231 0.000
Z88.5 Personal history of allergy to narcotic agent
0.769 0.231 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.768 0.232 0.000
I50.9 Heart failure, unspecified
0.767 0.232 0.000
Z98 Other postsurgical states
0.766 0.234 0.000
H35 Other retinal disorders
0.765 0.235 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.765 0.235 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.764 0.236 0.000
S89 Other and unspecified injuries of lower leg
0.764 0.236 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.764 0.236 0.000
H43 Disorders of vitreous body
0.762 0.238 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.761 0.239 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.760 0.239 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.759 0.241 0.000
M77 Other enthesopathies
0.758 0.242 0.000
G90-G99 Other disorders of the nervous system
0.757 0.243 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.756 0.244 0.000
S80 Superficial injury of lower leg
0.756 0.244 0.000
I73 Other peripheral vascular diseases
0.754 0.246 0.000
E11.4 With neurological complications
0.753 0.247 0.000
I47.1 Supraventricular tachycardia
0.751 0.249 0.000
H73 Other disorders of tympanic membrane
0.750 0.250 0.000
J90 Pleural effusion, not elsewhere classified
0.749 0.251 0.000
Z90.7 Acquired absence of genital organ(s)
0.749 0.251 0.000
I27 Other pulmonary heart diseases
0.748 0.252 0.000
I21 Acute myocardial infarction
0.748 0.252 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
G50.0 Trigeminal neuralgia
0.748 0.252 0.000
Z60 Problems related to social environment
0.746 0.254 0.000
Z90.3 Acquired absence of part of stomach
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.743 0.257 0.000
Chapter XX External causes of morbidity and mortality
0.743 0.257 0.000
Z88.2 Personal history of allergy to sulphonamides
0.743 0.257 0.000
I26 Pulmonary embolism
0.742 0.258 0.000
S65 Injury of blood vessels at wrist and hand level
0.741 0.259 0.000
Z90.8 Acquired absence of other organs
0.741 0.259 0.000
H52.1 Myopia
0.741 0.259 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.739 0.261 0.000
E40-E46 Malnutrition
0.738 0.262 0.000
I77.1 Stricture of artery
0.738 0.262 0.000
I38 Endocarditis, valve unspecified
0.738 0.262 0.000
I46.9 Cardiac arrest, unspecified
0.737 0.263 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.737 0.263 0.000
J20-J22 Other acute lower respiratory infections
0.736 0.264 0.000
G56.2 Lesion of ulnar nerve
0.735 0.265 0.000
I71.0 Dissection of aorta [any part]
0.735 0.265 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.732 0.268 0.000
J40 Bronchitis, not specified as acute or chronic
0.730 0.270 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.730 0.270 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.729 0.271 0.000
M05-M14 Inflammatory polyarthropathies
0.729 0.271 0.000
T66-T78 Other and unspecified effects of external causes
0.729 0.271 0.000
E73 Lactose intolerance
0.728 0.272 0.000
E87.2 Acidosis
0.728 0.272 0.000
M86-M90 Other osteopathies
0.728 0.272 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
S60 Superficial injury of wrist and hand
0.727 0.273 0.000
H34.8 Other retinal vascular occlusions
0.725 0.275 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.725 0.275 0.000
I46.0 Cardiac arrest with successful resuscitation
0.724 0.275 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.724 0.276 0.000
S82.3 Fracture of lower end of tibia
0.724 0.276 0.000
K65-K67 Diseases of peritoneum
0.724 0.276 0.000
M75.3 Calcific tendinitis of shoulder
0.722 0.278 0.000
I30 Acute pericarditis
0.722 0.278 0.000
J39 Other diseases of upper respiratory tract
0.722 0.278 0.000
I24 Other acute ischaemic heart diseases
0.721 0.279 0.000
I49.3 Ventricular premature depolarisation
0.721 0.279 0.000
N99-N99 Other disorders of the genitourinary system
0.719 0.281 0.000
H49 Paralytic strabismus
0.719 0.281 0.000
Z92 Personal history of medical treatment
0.718 0.282 0.000
J30 Vasomotor and allergic rhinitis
0.718 0.282 0.000
R00 Abnormalities of heart beat
0.718 0.282 0.000
K70 Alcoholic liver disease
0.718 0.282 0.000
R00.2 Palpitations
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E06 Thyroiditis
0.716 0.283 0.000
L20-L30 Dermatitis and eczema
0.713 0.286 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.713 0.287 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.713 0.287 0.000
N36 Other disorders of urethra
0.712 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.288 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.711 0.289 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.711 0.289 0.000
Z60.2 Living alone
0.710 0.290 0.000
I51.6 Cardiovascular disease, unspecified
0.710 0.290 0.000
I51.5 Myocardial degeneration
0.710 0.290 0.000
I51.4 Myocarditis, unspecified
0.710 0.290 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.710 0.290 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.710 0.290 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.710 0.290 0.000
I51.0 Cardiac septal defect, acquired
0.710 0.290 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.709 0.291 0.000
M75.9 Shoulder lesion, unspecified
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.708 0.292 0.000
T33-T35 Frostbite
0.707 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.292 0.000
I35.1 Aortic (valve) insufficiency
0.707 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.707 0.293 0.000
G47 Sleep disorders
0.705 0.295 0.000
J37 Chronic laryngitis and laryngotracheitis
0.705 0.295 0.000
I44.1 Atrioventricular block, second degree
0.705 0.295 0.000
E11.5 With peripheral circulatory complications
0.704 0.296 0.000
I42.9 Cardiomyopathy, unspecified
0.704 0.296 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.704 0.296 0.000
S67 Crushing injury of wrist and hand
0.703 0.297 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.701 0.299 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.701 0.299 0.000
M76 Enthesopathies of lower limb, excluding foot
0.701 0.299 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.701 0.299 0.000
Z95.4 Presence of other heart-valve replacement
0.700 0.300 0.000
Z93 Artificial opening status
0.698 0.302 0.000
J33 Nasal polyp
0.697 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.697 0.303 0.000
I72 Other aneurysm
0.697 0.303 0.000
H11 Other disorders of conjunctiva
0.697 0.303 0.000
M75.5 Bursitis of shoulder
0.697 0.303 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.696 0.304 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.696 0.304 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.695 0.305 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.695 0.305 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.695 0.305 0.000
Z89 Acquired absence of limb
0.695 0.305 0.000
N72 Inflammatory disease of cervix uteri
0.695 0.305 0.000
H72.8 Other perforations of tympanic membrane
0.694 0.306 0.000
I49.2 Junctional premature depolarisation
0.693 0.306 0.000
I49.1 Atrial premature depolarisation
0.693 0.306 0.000
E03.8 Other specified hypothyroidism
0.691 0.309 0.000
N32.0 Bladder-neck obstruction
0.690 0.310 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.689 0.311 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.689 0.311 0.000
H74 Other disorders of middle ear and mastoid
0.689 0.311 0.000
H70 Mastoiditis and related conditions
0.689 0.311 0.000
H68 Eustachian salpingitis and obstruction
0.689 0.311 0.000
H67 Otitis media in diseases classified elsewhere
0.689 0.311 0.000
H65.3 Chronic mucoid otitis media
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.687 0.313 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.686 0.314 0.000
H65.4 Other chronic nonsuppurative otitis media
0.686 0.314 0.000
I07 Rheumatic tricuspid valve diseases
0.686 0.314 0.000
G58 Other mononeuropathies
0.686 0.314 0.000
G25 Other extrapyramidal and movement disorders
0.685 0.315 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.684 0.316 0.000
G52 Disorders of other cranial nerves
0.684 0.316 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.684 0.316 0.000
S81 Open wound of lower leg
0.682 0.318 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.681 0.319 0.000
H31 Other disorders of choroid
0.681 0.319 0.000
H30 Chorioretinal inflammation
0.681 0.319 0.000
S70-S79 Injuries to the hip and thigh
0.681 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.681 0.319 0.000
E85 Amyloidosis
0.680 0.320 0.000
E84 Cystic fibrosis
0.680 0.320 0.000
E79 Disorders of purine and pyrimidine metabolism
0.680 0.320 0.000
E77 Disorders of glycoprotein metabolism
0.680 0.320 0.000
E76 Disorders of glycosaminoglycan metabolism
0.680 0.320 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.680 0.320 0.000
E74 Other disorders of carbohydrate metabolism
0.680 0.320 0.000
E72 Other disorders of amino-acid metabolism
0.680 0.320 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.680 0.320 0.000
E70 Disorders of aromatic amino-acid metabolism
0.680 0.320 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.680 0.320 0.000
N37 Urethral disorders in diseases classified elsewhere
0.680 0.320 0.000
N34 Urethritis and urethral syndrome
0.680 0.320 0.000
N33 Bladder disorders in diseases classified elsewhere
0.680 0.320 0.000
N30.1 Interstitial cystitis (chronic)
0.678 0.322 0.000
Chapter I Certain infectious and parasitic diseases
0.677 0.323 0.000
H34.2 Other retinal artery occlusions
0.677 0.323 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.677 0.323 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.676 0.323 0.000
H51 Other disorders of binocular movement
0.676 0.323 0.000
J95-J99 Other diseases of the respiratory system
0.676 0.324 0.000
I49.4 Other and unspecified premature depolarisation
0.676 0.324 0.000
N76 Other inflammation of vagina and vulva
0.676 0.324 0.000
G56.3 Lesion of radial nerve
0.675 0.325 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.675 0.325 0.000
H60 Otitis externa
0.674 0.325 0.000
Z90.1 Acquired absence of breast(s)
0.674 0.326 0.000
S64.4 Injury of digital nerve of other finger
0.674 0.326 0.000
H92 Otalgia and effusion of ear
0.674 0.326 0.000
I44.6 Other and unspecified fascicular block
0.673 0.327 0.000
I44.5 Left posterior fascicular block
0.673 0.327 0.000
I44.4 Left anterior fascicular block
0.673 0.327 0.000
I44.3 Other and unspecified atrioventricular block
0.673 0.327 0.000
M85 Other disorders of bone density and structure
0.673 0.327 0.000
M16.1 Other primary coxarthrosis
0.673 0.327 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.673 0.327 0.000
J38.1 Polyp of vocal cord and larynx
0.673 0.327 0.000
N30.3 Trigonitis
0.672 0.328 0.000
H43.8 Other disorders of vitreous body
0.672 0.328 0.000
S88 Traumatic amputation of lower leg
0.671 0.328 0.000
S87 Crushing injury of lower leg
0.671 0.328 0.000
S86 Injury of muscle and tendon at lower leg level
0.671 0.328 0.000
S85 Injury of blood vessels at lower leg level
0.671 0.328 0.000
S84 Injury of nerves at lower leg level
0.671 0.328 0.000
T87 Complications peculiar to reattachment and amputation
0.671 0.329 0.000
S82.0 Fracture of patella
0.670 0.330 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.670 0.330 0.000
S69 Other and unspecified injuries of wrist and hand
0.669 0.331 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.668 0.332 0.000
I78 Diseases of capillaries
0.668 0.332 0.000
H25-H28 Disorders of lens
0.668 0.332 0.000
E13 Other specified diabetes mellitus
0.667 0.333 0.000
I23 Certain current complications following acute myocardial infarction
0.666 0.334 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.666 0.334 0.000
M72.2 Plantar fascial fibromatosis
0.665 0.335 0.000
M72.9 Fibroblastic disorder, unspecified
0.665 0.335 0.000
M72.8 Other fibroblastic disorders
0.665 0.335 0.000
M72.6 Necrotizing fasciitis
0.665 0.335 0.000
M72.5 Fasciitis, not elsewhere classified
0.665 0.335 0.000
M72.4 Pseudosarcomatous fibromatosis
0.665 0.335 0.000
M72.3 Nodular fasciitis
0.665 0.335 0.000
M72.1 Knuckle pads
0.665 0.335 0.000
E11.2 With renal complications
0.665 0.335 0.000
N39.0 Urinary tract infection, site not specified
0.665 0.335 0.000
H90 Conductive and sensorineural hearing loss
0.664 0.336 0.000
M40-M43 Deforming dorsopathies
0.663 0.337 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.663 0.337 0.000
F99-F99 Unspecified mental disorder
0.663 0.337 0.000
M19.9 Arthrosis, unspecified
0.663 0.337 0.000
K50-K52 Noninfective enteritis and colitis
0.662 0.338 0.000
I34.0 Mitral (valve) insufficiency
0.661 0.339 0.000
L60 Nail disorders
0.661 0.339 0.000
L10-L14 Bullous disorders
0.660 0.339 0.000
M16.0 Primary coxarthrosis, bilateral
0.660 0.339 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.659 0.340 0.000
E00 Congenital iodine-deficiency syndrome
0.659 0.340 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.659 0.340 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.659 0.341 0.000
H17 Corneal scars and opacities
0.659 0.341 0.000
J03 Acute tonsillitis
0.659 0.341 0.000
E12 Malnutrition-related diabetes mellitus
0.659 0.341 0.000
S82.6 Fracture of lateral malleolus
0.658 0.341 0.000
H52.3 Anisometropia and aniseikonia
0.658 0.342 0.000
I34.1 Mitral (valve) prolapse
0.657 0.343 0.000
E50-E64 Other nutritional deficiencies
0.656 0.343 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.656 0.344 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.655 0.344 0.000
J00 Acute nasopharyngitis [common cold]
0.654 0.346 0.000
E88 Other metabolic disorders
0.654 0.346 0.000
S50-S59 Injuries to the elbow and forearm
0.653 0.346 0.000
N32.4 Rupture of bladder, nontraumatic
0.653 0.346 0.000
N32.2 Vesical fistula, not elsewhere classified
0.653 0.346 0.000
N32.1 Vesicointestinal fistula
0.653 0.346 0.000
I31.8 Other specified diseases of pericardium
0.653 0.347 0.000
I31.2 Haemopericardium, not elsewhere classified
0.653 0.347 0.000
I31.1 Chronic constrictive pericarditis
0.653 0.347 0.000
I31.0 Chronic adhesive pericarditis
0.653 0.347 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.653 0.347 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.652 0.348 0.000
L71 Rosacea
0.652 0.348 0.000
H50.1 Divergent concomitant strabismus
0.652 0.348 0.000
M94 Other disorders of cartilage
0.652 0.348 0.000
Z95.0 Presence of cardiac pacemaker
0.652 0.348 0.000
Z95.2 Presence of prosthetic heart valve
0.652 0.348 0.000
Z98.0 Intestinal bypass and anastomosis status
0.652 0.348 0.000
N30.9 Cystitis, unspecified
0.651 0.349 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.651 0.349 0.000
I09 Other rheumatic heart diseases
0.651 0.349 0.000
I06 Rheumatic aortic valve diseases
0.651 0.349 0.000
I05 Rheumatic mitral valve diseases
0.651 0.349 0.000
H18 Other disorders of cornea
0.651 0.349 0.000
Z97 Presence of other devices
0.650 0.350 0.000
I25.3 Aneurysm of heart
0.650 0.350 0.000
M80 Osteoporosis with pathological fracture
0.649 0.351 0.000
I33.0 Acute and subacute infective endocarditis
0.649 0.351 0.000
W00-W19 Falls
0.649 0.351 0.000
Q80-Q89 Other congenital malformations
0.648 0.351 0.000
N30.4 Irradiation cystitis
0.648 0.352 0.000
N30.0 Acute cystitis
0.648 0.352 0.000
T81.9 Unspecified complication of procedure
0.647 0.353 0.000
M84 Disorders of continuity of bone
0.647 0.353 0.000
G71 Primary disorders of muscles
0.647 0.353 0.000
G47.3 Sleep apnoea
0.647 0.353 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.645 0.355 0.000
L75 Apocrine sweat disorders
0.645 0.355 0.000
L74 Eccrine sweat disorders
0.645 0.355 0.000
L70 Acne
0.645 0.355 0.000
L68 Hypertrichosis
0.645 0.355 0.000
L67 Hair colour and hair shaft abnormalities
0.645 0.355 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.645 0.355 0.000
L65 Other nonscarring hair loss
0.645 0.355 0.000
L64 Androgenic alopecia
0.645 0.355 0.000
L63 Alopecia areata
0.645 0.355 0.000
L62 Nail disorders in diseases classified elsewhere
0.645 0.355 0.000
K65 Peritonitis
0.644 0.356 0.000
R21 Rash and other nonspecific skin eruption
0.643 0.357 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.643 0.357 0.000
I73.0 Raynaud's syndrome
0.643 0.357 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.642 0.358 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.641 0.359 0.000
S89.9 Unspecified injury of lower leg
0.641 0.359 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.641 0.359 0.000
L50-L54 Urticaria and erythema
0.640 0.359 0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.640 0.360 0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.640 0.360 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.640 0.360 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.640 0.360 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.640 0.360 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.640 0.360 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.640 0.360 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.640 0.360 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.640 0.360 0.000
T86 Failure and rejection of transplanted organs and tissues
0.640 0.360 0.000
I31.9 Disease of pericardium, unspecified
0.640 0.360 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.639 0.360 0.000
Z85 Personal history of malignant neoplasm
0.639 0.361 0.000
E20-E35 Disorders of other endocrine glands
0.639 0.361 0.000
I45 Other conduction disorders
0.638 0.361 0.000
M15 Polyarthrosis
0.638 0.362 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.638 0.362 0.000
G24 Dystonia
0.637 0.362 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.637 0.363 0.000
I28 Other diseases of pulmonary vessels
0.636 0.364 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.636 0.364 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.635 0.364 0.000
H35.8 Other specified retinal disorders
0.635 0.365 0.000
G61 Inflammatory polyneuropathy
0.635 0.365 0.000
M71.3 Other bursal cyst
0.635 0.365 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.634 0.366 0.000
J44 Other chronic obstructive pulmonary disease
0.634 0.366 0.000
H69.8 Other specified disorders of Eustachian tube
0.634 0.366 0.000
E78.2 Mixed hyperlipidaemia
0.634 0.366 0.000
M45-M49 Spondylopathies
0.633 0.366 0.000
L72.2 Steatocystoma multiplex
0.633 0.367 0.000
J32 Chronic sinusitis
0.633 0.367 0.000
H72.2 Other marginal perforations of tympanic membrane
0.632 0.367 0.000
H72.1 Attic perforation of tympanic membrane
0.632 0.367 0.000
I44.2 Atrioventricular block, complete
0.632 0.367 0.000
E80.4 Gilbert's syndrome
0.632 0.367 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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