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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115049412
log Bayes Factor = 15.9663
Chromosome 2   position 200,960,006  (GRCh37) Explore rs115049412 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I50.1 Left ventricular failure
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
I42 Cardiomyopathy
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
D00-D09 In situ neoplasms
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.992 0.008 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.991 0.009 0.000
I10-I15 Hypertensive diseases
0.989 0.011 0.000
I05-I09 Chronic rheumatic heart diseases
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.983 0.017 0.000
I42.0 Dilated cardiomyopathy
0.982 0.018 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.982 0.018 0.000
I10 Essential (primary) hypertension
0.980 0.020 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.979 0.021 0.000
M06 Other rheumatoid arthritis
0.979 0.021 0.000
I95 Hypotension
0.977 0.023 0.000
M06.9 Rheumatoid arthritis, unspecified
0.973 0.027 0.000
I08 Multiple valve diseases
0.973 0.027 0.000
I20-I25 Ischaemic heart diseases
0.972 0.028 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.970 0.030 0.000
E10-E14 Diabetes mellitus
0.968 0.032 0.000
I42.9 Cardiomyopathy, unspecified
0.963 0.037 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.962 0.038 0.000
E70-E90 Metabolic disorders
0.956 0.044 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.955 0.045 0.000
I22 Subsequent myocardial infarction
0.954 0.046 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.954 0.046 0.000
Chapter I Certain infectious and parasitic diseases
0.953 0.047 0.000
I95.9 Hypotension, unspecified
0.952 0.048 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.952 0.048 0.000
C34 Malignant neoplasm of bronchus and lung
0.951 0.049 0.000
B95-B98 Bacterial, viral and other infectious agents
0.950 0.050 0.000
E10 Insulin-dependent diabetes mellitus
0.945 0.055 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.945 0.055 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.942 0.058 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.940 0.060 0.000
C15-C26 Malignant neoplasms of digestive organs
0.938 0.062 0.000
E87.2 Acidosis
0.937 0.063 0.000
D05 Carcinoma in situ of breast
0.936 0.064 0.000
C34.1 Upper lobe, bronchus or lung
0.931 0.069 0.000
S40-S49 Injuries to the shoulder and upper arm
0.930 0.070 0.000
S90-S99 Injuries to the ankle and foot
0.928 0.072 0.000
D04 Carcinoma in situ of skin
0.924 0.076 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.923 0.077 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.920 0.080 0.000
D05.1 Intraductal carcinoma in situ
0.918 0.082 0.000
W00-W19 Falls
0.917 0.083 0.000
I51 Complications and ill-defined descriptions of heart disease
0.911 0.089 0.000
I31 Other diseases of pericardium
0.908 0.092 0.000
M81 Osteoporosis without pathological fracture
0.904 0.096 0.000
I86 Varicose veins of other sites
0.904 0.096 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.903 0.097 0.000
I85 Oesophageal varices
0.902 0.098 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.902 0.098 0.000
I80 Phlebitis and thrombophlebitis
0.901 0.099 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.898 0.102 0.000
Chapter V Mental and behavioural disorders
0.891 0.109 0.000
I51.8 Other ill-defined heart diseases
0.889 0.111 0.000
I22.8 Subsequent myocardial infarction of other sites
0.886 0.114 0.000
I81 Portal vein thrombosis
0.884 0.116 0.000
I95.2 Hypotension due to drugs
0.883 0.117 0.000
I47 Paroxysmal tachycardia
0.882 0.118 0.000
S10-S19 Injuries to the neck
0.881 0.119 0.000
M84 Disorders of continuity of bone
0.879 0.121 0.000
D03 Melanoma in situ
0.879 0.121 0.000
E50-E64 Other nutritional deficiencies
0.876 0.124 0.000
I24 Other acute ischaemic heart diseases
0.873 0.127 0.000
M70-M79 Other soft tissue disorders
0.873 0.127 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.872 0.128 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.872 0.128 0.000
W50-W64 Exposure to animate mechanical forces
0.870 0.130 0.000
T66-T78 Other and unspecified effects of external causes
0.869 0.131 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.868 0.132 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.864 0.136 0.000
M05 Seropositive rheumatoid arthritis
0.864 0.136 0.000
F30-F39 Mood [affective] disorders
0.864 0.136 0.000
Q60-Q64 Congenital malformations of the urinary system
0.863 0.137 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.859 0.141 0.000
C16 Malignant neoplasm of stomach
0.857 0.143 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.856 0.144 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.856 0.144 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.854 0.146 0.000
E10.3 With ophthalmic complications
0.850 0.150 0.000
M81.9 Osteoporosis, unspecified
0.850 0.150 0.000
T88.4 Failed or difficult intubation
0.848 0.152 0.000
E87.6 Hypokalaemia
0.845 0.155 0.000
E00-E07 Disorders of thyroid gland
0.845 0.155 0.000
F31 Bipolar affective disorder
0.845 0.155 0.000
C32 Malignant neoplasm of larynx
0.845 0.155 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.844 0.156 0.000
I82 Other venous embolism and thrombosis
0.843 0.157 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.842 0.158 0.000
I86.4 Gastric varices
0.840 0.160 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.838 0.162 0.000
W20-W49 Exposure to inanimate mechanical forces
0.838 0.162 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.834 0.166 0.000
M86-M90 Other osteopathies
0.827 0.173 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.826 0.174 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.823 0.177 0.000
Y40 Systemic antibiotics
0.819 0.181 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.818 0.182 0.000
W07 Fall involving chair
0.818 0.182 0.000
I06 Rheumatic aortic valve diseases
0.817 0.183 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.817 0.183 0.000
I85.9 Oesophageal varices without bleeding
0.817 0.183 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.816 0.184 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.815 0.185 0.000
E53 Deficiency of other B group vitamins
0.814 0.186 0.000
M06.0 Seronegative rheumatoid arthritis
0.813 0.187 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.809 0.191 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.809 0.191 0.000
Q61 Cystic kidney disease
0.808 0.192 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.807 0.193 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.806 0.194 0.000
C17 Malignant neoplasm of small intestine
0.806 0.194 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.806 0.194 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.803 0.197 0.000
I30 Acute pericarditis
0.803 0.197 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.803 0.197 0.000
S91 Open wound of ankle and foot
0.802 0.198 0.000
D09 Carcinoma in situ of other and unspecified sites
0.802 0.198 0.000
E10.9 Without complications
0.801 0.199 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.800 0.200 0.000
S90 Superficial injury of ankle and foot
0.797 0.203 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.796 0.204 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.796 0.204 0.000
C18 Malignant neoplasm of colon
0.795 0.205 0.000
I50.9 Heart failure, unspecified
0.795 0.205 0.000
C64-C68 Malignant neoplasms of urinary tract
0.795 0.205 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.794 0.206 0.000
F31.9 Bipolar affective disorder, unspecified
0.793 0.207 0.000
V01-V09 Pedestrian injured in transport accident
0.793 0.207 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.791 0.209 0.000
D04.6 Skin of upper limb, including shoulder
0.789 0.211 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.789 0.211 0.000
W10 Fall on and from stairs and steps
0.788 0.212 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.788 0.212 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.788 0.212 0.000
I31.3 Pericardial effusion (noninflammatory)
0.785 0.215 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.785 0.215 0.000
I24.8 Other forms of acute ischaemic heart disease
0.784 0.216 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.783 0.217 0.000
M91-M94 Chondropathies
0.782 0.218 0.000
C20 Malignant neoplasm of rectum
0.782 0.218 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.781 0.219 0.000
C51-C58 Malignant neoplasms of female genital organs
0.781 0.219 0.000
E10.2 With renal complications
0.781 0.219 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.779 0.221 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.777 0.223 0.000
E11 Non-insulin-dependent diabetes mellitus
0.776 0.224 0.000
Y52 Agents primarily affecting the cardiovascular system
0.775 0.225 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.774 0.226 0.000
C09 Malignant neoplasm of tonsil
0.773 0.227 0.000
S12 Fracture of neck
0.773 0.227 0.000
D04.5 Skin of trunk
0.772 0.228 0.000
L40-L45 Papulosquamous disorders
0.771 0.229 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.771 0.229 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.771 0.229 0.000
M40-M43 Deforming dorsopathies
0.771 0.229 0.000
I31.9 Disease of pericardium, unspecified
0.770 0.230 0.000
F30 Manic episode
0.769 0.231 0.000
E53.8 Deficiency of other specified B group vitamins
0.769 0.231 0.000
C18.0 Caecum
0.769 0.231 0.000
I38 Endocarditis, valve unspecified
0.768 0.231 0.000
I15 Secondary hypertension
0.768 0.232 0.000
W07.0 Home
0.763 0.237 0.000
S80-S89 Injuries to the knee and lower leg
0.762 0.238 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.760 0.239 0.000
E05.9 Thyrotoxicosis, unspecified
0.761 0.239 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.758 0.242 0.000
E10.4 With neurological complications
0.758 0.242 0.000
I47.1 Supraventricular tachycardia
0.757 0.243 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.756 0.244 0.000
D06 Carcinoma in situ of cervix uteri
0.755 0.245 0.000
C34.0 Main bronchus
0.754 0.246 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.754 0.246 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.754 0.246 0.000
E87.7 Fluid overload
0.753 0.247 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.752 0.248 0.000
M81.98 Osteoporosis, unspecified (Other)
0.751 0.249 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.751 0.249 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.751 0.249 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.751 0.249 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.751 0.249 0.000
D68 Other coagulation defects
0.751 0.249 0.000
I21 Acute myocardial infarction
0.749 0.251 0.000
T78 Adverse effects, not elsewhere classified
0.748 0.251 0.000
I42.2 Other hypertrophic cardiomyopathy
0.748 0.252 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.748 0.252 0.000
Y48 Anaesthetics and therapeutic gases
0.748 0.252 0.000
E87.0 Hyperosmolality and hypernatraemia
0.748 0.252 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.747 0.253 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.746 0.254 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.746 0.254 0.000
M00-M03 Infectious arthropathies
0.745 0.255 0.000
V20-V29 Motorcycle rider injured in transport accident
0.745 0.255 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.745 0.255 0.000
S41 Open wound of shoulder and upper arm
0.745 0.255 0.000
I82.8 Embolism and thrombosis of other specified veins
0.745 0.255 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.744 0.256 0.000
E11.4 With neurological complications
0.743 0.257 0.000
D04.7 Skin of lower limb, including hip
0.743 0.257 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.742 0.258 0.000
D69 Purpura and other haemorrhagic conditions
0.742 0.258 0.000
I87 Other disorders of veins
0.742 0.258 0.000
V80-V89 Other land transport accidents
0.741 0.259 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.741 0.259 0.000
M81.4 Drug-induced osteoporosis
0.740 0.260 0.000
M75 Shoulder lesions
0.739 0.261 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.736 0.264 0.000
M06.3 Rheumatoid nodule
0.736 0.264 0.000
C16.9 Stomach, unspecified
0.736 0.264 0.000
D55-D59 Haemolytic anaemias
0.733 0.266 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.733 0.267 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.732 0.268 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.732 0.268 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.731 0.269 0.000
T87 Complications peculiar to reattachment and amputation
0.731 0.269 0.000
I95.8 Other hypotension
0.731 0.269 0.000
Chapter VIII Diseases of the ear and mastoid process
0.729 0.271 0.000
E80.4 Gilbert's syndrome
0.728 0.272 0.000
I99 Other and unspecified disorders of circulatory system
0.728 0.272 0.000
B99-B99 Other infectious diseases
0.727 0.273 0.000
C16.5 Lesser curvature of stomach, unspecified
0.727 0.273 0.000
I24.1 Dressler's syndrome
0.726 0.274 0.000
W13 Fall from, out of or through building or structure
0.726 0.274 0.000
E10.5 With peripheral circulatory complications
0.725 0.275 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.725 0.275 0.000
L82 Seborrhoeic keratosis
0.725 0.275 0.000
S81 Open wound of lower leg
0.724 0.276 0.000
I88 Nonspecific lymphadenitis
0.724 0.276 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.722 0.278 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.722 0.278 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.721 0.279 0.000
F99-F99 Unspecified mental disorder
0.721 0.279 0.000
I05 Rheumatic mitral valve diseases
0.720 0.280 0.000
Q50-Q56 Congenital malformations of genital organs
0.720 0.280 0.000
I12 Hypertensive renal disease
0.719 0.281 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.719 0.281 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C32.0 Glottis
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
S37 Injury of urinary and pelvic organs
0.716 0.284 0.000
D05.0 Lobular carcinoma in situ
0.716 0.284 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.715 0.285 0.000
I42.6 Alcoholic cardiomyopathy
0.715 0.285 0.000
I42.5 Other restrictive cardiomyopathy
0.715 0.285 0.000
I42.4 Endocardial fibroelastosis
0.715 0.285 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.715 0.285 0.000
W55 Bitten or struck by other mammals
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.285 0.000
Y40.8 Other systemic antibiotics
0.714 0.286 0.000
D03.5 Melanoma in situ of trunk
0.714 0.286 0.000
S99 Other and unspecified injuries of ankle and foot
0.714 0.286 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.714 0.286 0.000
C09.9 Tonsil, unspecified
0.714 0.286 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.713 0.287 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.713 0.287 0.000
W17 Other fall from one level to another
0.712 0.288 0.000
I46 Cardiac arrest
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
I50.0 Congestive heart failure
0.711 0.289 0.000
T88.5 Other complications of anaesthesia
0.710 0.290 0.000
E10.6 With other specified complications
0.709 0.291 0.000
I85.0 Oesophageal varices with bleeding
0.709 0.291 0.000
I13 Hypertensive heart and renal disease
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.709 0.291 0.000
C23 Malignant neoplasm of gallbladder
0.708 0.292 0.000
I09 Other rheumatic heart diseases
0.707 0.292 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.707 0.293 0.000
I95.0 Idiopathic hypotension
0.706 0.294 0.000
T82.1 Mechanical complication of cardiac electronic device
0.705 0.295 0.000
M12 Other specific arthropathies
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
M08 Juvenile arthritis
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.703 0.296 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.703 0.297 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.702 0.298 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.702 0.298 0.000
C31 Malignant neoplasm of accessory sinuses
0.702 0.298 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.702 0.298 0.000
C37 Malignant neoplasm of thymus
0.702 0.298 0.000
C33 Malignant neoplasm of trachea
0.702 0.298 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.298 0.000
M06.2 Rheumatoid bursitis
0.702 0.298 0.000
M06.1 Adult-onset Still's disease
0.702 0.298 0.000
M75.4 Impingement syndrome of shoulder
0.700 0.300 0.000
B15-B19 Viral hepatitis
0.699 0.301 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.699 0.301 0.000
S43.0 Dislocation of shoulder joint
0.699 0.301 0.000
S91.3 Open wound of other parts of foot
0.698 0.302 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.698 0.302 0.000
A15-A19 Tuberculosis
0.698 0.302 0.000
M60-M63 Disorders of muscles
0.698 0.302 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.698 0.302 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.698 0.302 0.000
I08.9 Multiple valve disease, unspecified
0.698 0.302 0.000
S50-S59 Injuries to the elbow and forearm
0.697 0.303 0.000
Q61.2 Polycystic kidney, adult type
0.697 0.303 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.697 0.303 0.000
I23 Certain current complications following acute myocardial infarction
0.697 0.303 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.696 0.304 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.696 0.304 0.000
I06.1 Rheumatic aortic insufficiency
0.695 0.304 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.695 0.305 0.000
Y57 Other and unspecified drugs and medicaments
0.694 0.306 0.000
E12 Malnutrition-related diabetes mellitus
0.694 0.306 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.694 0.306 0.000
E20-E35 Disorders of other endocrine glands
0.694 0.306 0.000
W08 Fall involving other furniture
0.693 0.307 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.693 0.307 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.692 0.307 0.000
T75 Effects of other external causes
0.692 0.308 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.692 0.308 0.000
S81.8 Open wound of other parts of lower leg
0.692 0.308 0.000
E13 Other specified diabetes mellitus
0.692 0.308 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.691 0.309 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.691 0.309 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.691 0.309 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.691 0.309 0.000
L43 Lichen planus
0.690 0.310 0.000
D80-D89 Certain disorders involving the immune mechanism
0.689 0.311 0.000
C34.2 Middle lobe, bronchus or lung
0.688 0.311 0.000
F30.9 Manic episode, unspecified
0.688 0.312 0.000
S36 Injury of intra-abdominal organs
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
S42 Fracture of shoulder and upper arm
0.687 0.313 0.000
S92 Fracture of foot, except ankle
0.687 0.313 0.000
I33 Acute and subacute endocarditis
0.686 0.313 0.000
E84 Cystic fibrosis
0.686 0.314 0.000
E79 Disorders of purine and pyrimidine metabolism
0.686 0.314 0.000
E77 Disorders of glycoprotein metabolism
0.686 0.314 0.000
E76 Disorders of glycosaminoglycan metabolism
0.686 0.314 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.686 0.314 0.000
E72 Other disorders of amino-acid metabolism
0.686 0.314 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.686 0.314 0.000
E70 Disorders of aromatic amino-acid metabolism
0.686 0.314 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.686 0.314 0.000
D04.4 Skin of scalp and neck
0.685 0.314 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.685 0.315 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.685 0.315 0.000
M83 Adult osteomalacia
0.685 0.315 0.000
T88.9 Complication of surgical and medical care, unspecified
0.684 0.316 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.684 0.316 0.000
T88.2 Shock due to anaesthesia
0.684 0.316 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.684 0.316 0.000
T88.0 Infection following immunisation
0.684 0.316 0.000
M10 Gout
0.684 0.316 0.000
Y00-Y09 Assault
0.683 0.317 0.000
M82 Osteoporosis in diseases classified elsewhere
0.683 0.317 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.683 0.317 0.000
B50-B64 Protozoal diseases
0.683 0.317 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.683 0.317 0.000
A75-A79 Rickettsioses
0.683 0.317 0.000
A70-A74 Other diseases caused by chlamydiae
0.683 0.317 0.000
A65-A69 Other spirochaetal diseases
0.683 0.317 0.000
A20-A28 Certain zoonotic bacterial diseases
0.683 0.317 0.000
W25 Contact with sharp glass
0.683 0.317 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.682 0.318 0.000
S19 Other and unspecified injuries of neck
0.682 0.318 0.000
C34.8 Overlapping lesion of bronchus and lung
0.682 0.318 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.681 0.319 0.000
E74 Other disorders of carbohydrate metabolism
0.681 0.319 0.000
V10-V19 Pedal cyclist injured in transport accident
0.681 0.319 0.000
S12.2 Fracture of other specified cervical vertebra
0.680 0.320 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.679 0.321 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.679 0.321 0.000
M84.4 Pathological fracture, not elsewhere classified
0.679 0.321 0.000
M45-M49 Spondylopathies
0.678 0.322 0.000
S89 Other and unspecified injuries of lower leg
0.678 0.322 0.000
E85 Amyloidosis
0.678 0.322 0.000
E10.8 With unspecified complications
0.677 0.322 0.000
E10.7 With multiple complications
0.677 0.322 0.000
E10.0 With coma
0.677 0.322 0.000
M76 Enthesopathies of lower limb, excluding foot
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.677 0.323 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.677 0.323 0.000
M87 Osteonecrosis
0.677 0.323 0.000
C17.9 Small intestine, unspecified
0.676 0.324 0.000
D01.0 Colon
0.676 0.324 0.000
E40-E46 Malnutrition
0.676 0.324 0.000
C12 Malignant neoplasm of pyriform sinus
0.676 0.324 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.674 0.325 0.000
S20-S29 Injuries to the thorax
0.674 0.326 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.674 0.326 0.000
E87.4 Mixed disorder of acid-base balance
0.674 0.326 0.000
W11 Fall on and from ladder
0.673 0.327 0.000
C18.9 Colon, unspecified
0.673 0.327 0.000
Q61.0 Congenital single renal cyst
0.673 0.327 0.000
M06.4 Inflammatory polyarthropathy
0.673 0.327 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
C32.9 Larynx, unspecified
0.672 0.328 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.672 0.328 0.000
Q61.3 Polycystic kidney, unspecified
0.672 0.328 0.000
W10.8 Other specified place
0.671 0.329 0.000
B07 Viral warts
0.671 0.329 0.000
D05.7 Other carcinoma in situ of breast
0.671 0.329 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.670 0.330 0.000
E10.1 With ketoacidosis
0.670 0.330 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.669 0.331 0.000
I37 Pulmonary valve disorders
0.669 0.331 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.669 0.331 0.000
S48 Traumatic amputation of shoulder and upper arm
0.667 0.333 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.667 0.333 0.000
S44 Injury of nerves at shoulder and upper arm level
0.667 0.333 0.000
S47 Crushing injury of shoulder and upper arm
0.667 0.333 0.000
M43 Other deforming dorsopathies
0.667 0.333 0.000
I89.0 Lymphoedema, not elsewhere classified
0.666 0.333 0.000
S98 Traumatic amputation of ankle and foot
0.665 0.334 0.000
S97 Crushing injury of ankle and foot
0.665 0.334 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.665 0.334 0.000
S95 Injury of blood vessels at ankle and foot level
0.665 0.334 0.000
S94 Injury of nerves at ankle and foot level
0.665 0.334 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.664 0.335 0.000
D09.0 Bladder
0.664 0.336 0.000
I11 Hypertensive heart disease
0.663 0.337 0.000
I30.9 Acute pericarditis, unspecified
0.663 0.337 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.663 0.337 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.663 0.337 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.663 0.337 0.000
D04.9 Skin, unspecified
0.663 0.337 0.000
D04.8 Skin of other sites
0.663 0.337 0.000
D04.2 Skin of ear and external auricular canal
0.663 0.337 0.000
D04.1 Skin of eyelid, including canthus
0.663 0.337 0.000
D04.0 Skin of lip
0.663 0.337 0.000
D47.1 Chronic myeloproliferative disease
0.663 0.337 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.662 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.662 0.338 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.662 0.338 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.662 0.338 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.662 0.338 0.000
S31 Open wound of abdomen, lower back and pelvis
0.662 0.338 0.000
W18 Other fall on same level
0.662 0.338 0.000
C15 Malignant neoplasm of oesophagus
0.661 0.339 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.661 0.339 0.000
Y59 Other and unspecified vaccines and biological substances
0.660 0.340 0.000
Y58 Bacterial vaccines
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.660 0.340 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.660 0.340 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.660 0.340 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.660 0.340 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.660 0.340 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.659 0.341 0.000
M79.6 Pain in limb
0.659 0.341 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.659 0.341 0.000
I86.8 Varicose veins of other specified sites
0.659 0.341 0.000
E89.0 Postprocedural hypothyroidism
0.659 0.341 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.658 0.341 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.658 0.342 0.000
S43.1 Dislocation of acromioclavicular joint
0.658 0.342 0.000
I15.9 Seconday hypertension, unspecified
0.658 0.342 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.658 0.342 0.000
I35 Nonrheumatic aortic valve disorders
0.658 0.342 0.000
I07 Rheumatic tricuspid valve diseases
0.657 0.342 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.657 0.343 0.000
W15 Fall from cliff
0.657 0.343 0.000
W14 Fall from tree
0.657 0.343 0.000
W12 Fall on and from scaffolding
0.657 0.343 0.000
W09 Fall involving playground equipment
0.657 0.343 0.000
W05 Fall involving wheelchair
0.657 0.343 0.000
W04 Fall while being carried or supported by other persons
0.657 0.343 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.657 0.343 0.000
W00 Fall on same level involving ice and snow
0.657 0.343 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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