TreeWAS – Variant ID: rs115062572

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
K50-K52 Noninfective enteritis and colitis	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K51 Ulcerative colitis	1.000	0.000	0.000
R30-R39 Symptoms and signs involving the urinary system	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
K55-K64 Other diseases of intestines	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
K50 Crohn's disease [regional enteritis]	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
Z93.2 Ileostomy status	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
J30-J39 Other diseases of upper respiratory tract	0.997	0.003	0.000
R33 Retention of urine	0.997	0.003	0.000
E70-E90 Metabolic disorders	0.996	0.004	0.000
K50.9 Crohn's disease, unspecified	0.996	0.004	0.000
K62 Other diseases of anus and rectum	0.996	0.004	0.000
Chapter XIV Diseases of the genitourinary system	0.995	0.005	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.995	0.005	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.994	0.006	0.000
K62.8 Other specified diseases of anus and rectum	0.994	0.006	0.000
Chapter VIII Diseases of the ear and mastoid process	0.991	0.009	0.000
K30 Dyspepsia	0.990	0.010	0.000
E78.0 Pure hypercholesterolaemia	0.989	0.011	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.989	0.011	0.000
J20-J22 Other acute lower respiratory infections	0.987	0.013	0.000
N20-N23 Urolithiasis	0.983	0.017	0.000
Chapter VII Diseases of the eye and adnexa	0.982	0.018	0.000
K50.1 Crohn's disease of large intestine	0.982	0.018	0.000
H65-H75 Diseases of middle ear and mastoid	0.982	0.018	0.000
R05 Cough	0.982	0.018	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.980	0.020	0.000
K52 Other non-infective gastro-enteritis and colitis	0.980	0.020	0.000
J31.0 Chronic rhinitis	0.980	0.020	0.000
J22 Unspecified acute lower respiratory infection	0.979	0.021	0.000
N20 Calculus of kidney and ureter	0.978	0.022	0.000
K20 Oesophagitis	0.976	0.024	0.000
N20.0 Calculus of kidney	0.973	0.027	0.000
K61 Abscess of anal and rectal regions	0.972	0.028	0.000
J32 Chronic sinusitis	0.968	0.032	0.000
N99-N99 Other disorders of the genitourinary system	0.966	0.034	0.000
K60 Fissure and fistula of anal and rectal regions	0.963	0.037	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.961	0.039	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.960	0.040	0.000
Chapter V Mental and behavioural disorders	0.957	0.043	0.000
K90.0 Coeliac disease	0.000	0.048	0.952
J40-J47 Chronic lower respiratory diseases	0.950	0.050	0.000
S40-S49 Injuries to the shoulder and upper arm	0.950	0.050	0.000
K63 Other diseases of intestine	0.946	0.054	0.000
F30-F39 Mood [affective] disorders	0.946	0.054	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.944	0.056	0.000
K61.0 Anal abscess	0.943	0.057	0.000
E78.5 Hyperlipidaemia, unspecified	0.943	0.057	0.000
J32.9 Chronic sinusitis, unspecified	0.941	0.059	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.935	0.065	0.000
J47 Bronchiectasis	0.923	0.077	0.000
H53-H54 Visual disturbances and blindness	0.914	0.086	0.000
S00-S09 Injuries to the head	0.914	0.086	0.000
H72 Perforation of tympanic membrane	0.913	0.087	0.000
F33 Recurrent depressive disorder	0.906	0.094	0.000
Chapter IX Diseases of the circulatory system	0.906	0.094	0.000
K60.3 Anal fistula	0.906	0.094	0.000
K62.1 Rectal polyp	0.903	0.097	0.000
N60-N64 Disorders of breast	0.902	0.098	0.000
K63.8 Other specified diseases of intestine	0.902	0.098	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.898	0.102	0.000
H60-H62 Diseases of external ear	0.898	0.102	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.895	0.105	0.000
J60-J70 Lung diseases due to external agents	0.888	0.112	0.000
K90-K93 Other diseases of the digestive system	0.830	0.112	0.057
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.881	0.119	0.000
K51.4 Pseudopolyposis of colon	0.875	0.125	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.873	0.127	0.000
K52.1 Toxic gastro-enteritis and colitis	0.871	0.129	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.870	0.130	0.000
T66-T78 Other and unspecified effects of external causes	0.869	0.131	0.000
K62.6 Ulcer of anus and rectum	0.869	0.131	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.866	0.134	0.000
I05-I09 Chronic rheumatic heart diseases	0.865	0.135	0.000
R25 Abnormal involuntary movements	0.864	0.136	0.000
H71 Cholesteatoma of middle ear	0.864	0.136	0.000
I20-I25 Ischaemic heart diseases	0.863	0.137	0.000
T79-T79 Certain early complications of trauma	0.861	0.139	0.000
E06 Thyroiditis	0.859	0.141	0.000
N64 Other disorders of breast	0.859	0.141	0.000
Z93 Artificial opening status	0.858	0.142	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.857	0.142	0.000
S02 Fracture of skull and facial bones	0.854	0.146	0.000
M70-M79 Other soft tissue disorders	0.854	0.146	0.000
S42 Fracture of shoulder and upper arm	0.853	0.147	0.000
H02 Other disorders of eyelid	0.850	0.150	0.000
R26 Abnormalities of gait and mobility	0.850	0.150	0.000
K51.2 Ulcerative (chronic) proctitis	0.849	0.151	0.000
F30 Manic episode	0.846	0.154	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.845	0.155	0.000
E50-E64 Other nutritional deficiencies	0.844	0.156	0.000
K22 Other diseases of oesophagus	0.841	0.159	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.840	0.160	0.000
I08 Multiple valve diseases	0.837	0.163	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.806	0.165	0.028
Chapter XX External causes of morbidity and mortality	0.834	0.166	0.000
N10-N16 Renal tubulo-interstitial diseases	0.833	0.167	0.000
N40-N51 Diseases of male genital organs	0.832	0.168	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.832	0.168	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.829	0.171	0.000
S20-S29 Injuries to the thorax	0.827	0.173	0.000
M75 Shoulder lesions	0.827	0.173	0.000
K50.0 Crohn's disease of small intestine	0.826	0.174	0.000
H73 Other disorders of tympanic membrane	0.826	0.174	0.000
K60.2 Anal fissure, unspecified	0.825	0.175	0.000
H61 Other disorders of external ear	0.823	0.177	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.822	0.178	0.000
H74 Other disorders of middle ear and mastoid	0.818	0.182	0.000
M65-M68 Disorders of synovium and tendon	0.818	0.182	0.000
H54 Blindness and low vision	0.817	0.183	0.000
J35 Chronic diseases of tonsils and adenoids	0.817	0.183	0.000
H65 Nonsuppurative otitis media	0.815	0.185	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.815	0.185	0.000
N20.2 Calculus of kidney with calculus of ureter	0.814	0.186	0.000
K22.7 Barrett's oesophagus	0.814	0.186	0.000
K62.2 Anal prolapse	0.813	0.187	0.000
K59 Other functional intestinal disorders	0.812	0.188	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.811	0.189	0.000
J44 Other chronic obstructive pulmonary disease	0.810	0.190	0.000
H72.0 Central perforation of tympanic membrane	0.809	0.191	0.000
J69 Pneumonitis due to solids and liquids	0.809	0.191	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.809	0.191	0.000
F33.9 Recurrent depressive disorder, unspecified	0.808	0.192	0.000
H55-H59 Other disorders of eye and adnexa	0.807	0.192	0.000
F31 Bipolar affective disorder	0.804	0.196	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.803	0.196	0.000
H02.9 Disorder of eyelid, unspecified	0.803	0.197	0.000
N99.0 Postprocedural renal failure	0.802	0.198	0.000
J31.2 Chronic pharyngitis	0.801	0.199	0.000
K40-K46 Hernia	0.800	0.200	0.000
T42.4 Benzodiazepines	0.799	0.201	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.798	0.202	0.000
R27 Other lack of coordination	0.797	0.203	0.000
S42.0 Fracture of clavicle	0.795	0.205	0.000
K52.3 Indeterminate colitis	0.795	0.205	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.792	0.208	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.791	0.209	0.000
N64.9 Disorder of breast, unspecified	0.791	0.209	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.791	0.209	0.000
K27 Peptic ulcer, site unspecified	0.791	0.209	0.000
S10-S19 Injuries to the neck	0.791	0.209	0.000
J34 Other disorders of nose and nasal sinuses	0.791	0.209	0.000
K12 Stomatitis and related lesions	0.790	0.210	0.000
I21 Acute myocardial infarction	0.790	0.210	0.000
K61.3 Ischiorectal abscess	0.787	0.213	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.787	0.213	0.000
K62.7 Radiation proctitis	0.786	0.213	0.000
K51.8 Other ulcerative colitis	0.786	0.214	0.000
H53 Visual disturbances	0.785	0.215	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.785	0.215	0.000
E40-E46 Malnutrition	0.782	0.218	0.000
Chapter VI Diseases of the nervous system	0.782	0.218	0.000
K91.4 Colostomy and enterostomy malfunction	0.775	0.218	0.007
K63.5 Polyp of colon	0.781	0.219	0.000
S09 Other and unspecified injuries of head	0.780	0.220	0.000
N61 Inflammatory disorders of breast	0.779	0.221	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.774	0.226	0.000
E07 Other disorders of thyroid	0.774	0.226	0.000
K51.5 Mucosal proctocolitis	0.773	0.227	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.773	0.227	0.000
Chapter II Neoplasms	0.772	0.228	0.000
N50 Other disorders of male genital organs	0.771	0.229	0.000
M75.1 Rotator cuff syndrome	0.769	0.231	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.769	0.231	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.768	0.232	0.000
E78.2 Mixed hyperlipidaemia	0.767	0.233	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.767	0.233	0.000
J40 Bronchitis, not specified as acute or chronic	0.767	0.233	0.000
K90 Intestinal malabsorption	0.362	0.234	0.404
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.764	0.236	0.000
M65 Synovitis and tenosynovitis	0.764	0.236	0.000
M45-M49 Spondylopathies	0.763	0.237	0.000
H40-H42 Glaucoma	0.763	0.237	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.762	0.238	0.000
S40 Superficial injury of shoulder and upper arm	0.761	0.238	0.000
E78.4 Other hyperlipidaemia	0.761	0.239	0.000
I08.0 Disorders of both mitral and aortic valves	0.761	0.239	0.000
R04 Haemorrhage from respiratory passages	0.761	0.239	0.000
K70-K77 Diseases of liver	0.760	0.240	0.000
E10-E14 Diabetes mellitus	0.760	0.240	0.000
E06.3 Autoimmune thyroiditis	0.759	0.241	0.000
H20 Iridocyclitis	0.758	0.242	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.758	0.242	0.000
I22 Subsequent myocardial infarction	0.758	0.242	0.000
Z93.3 Colostomy status	0.756	0.244	0.000
K50.8 Other Crohn's disease	0.756	0.244	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.747	0.245	0.008
S42.00 Fracture of clavicle (closed)	0.754	0.245	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.753	0.247	0.000
J69.0 Pneumonitis due to food and vomit	0.752	0.248	0.000
Z93.1 Gastrostomy status	0.751	0.249	0.000
E86 Volume depletion	0.748	0.252	0.000
T78 Adverse effects, not elsewhere classified	0.747	0.253	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.745	0.255	0.000
R39 Other symptoms and signs involving the urinary system	0.745	0.255	0.000
M75.4 Impingement syndrome of shoulder	0.745	0.255	0.000
F30.9 Manic episode, unspecified	0.744	0.256	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.743	0.256	0.000
E88 Other metabolic disorders	0.743	0.257	0.000
H61.2 Impacted cerumen	0.743	0.257	0.000
J32.8 Other chronic sinusitis	0.742	0.258	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.741	0.258	0.000
R34 Anuria and oliguria	0.740	0.260	0.000
J32.4 Chronic pansinusitis	0.740	0.260	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.740	0.260	0.000
K63.0 Abscess of intestine	0.736	0.264	0.000
J86 Pyothorax	0.734	0.266	0.000
K65-K67 Diseases of peritoneum	0.733	0.267	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.733	0.267	0.000
J30 Vasomotor and allergic rhinitis	0.733	0.267	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.732	0.268	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.732	0.268	0.000
K12.1 Other forms of stomatitis	0.730	0.270	0.000
S50-S59 Injuries to the elbow and forearm	0.729	0.271	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.728	0.272	0.000
Q50-Q56 Congenital malformations of genital organs	0.728	0.272	0.000
E87.2 Acidosis	0.728	0.272	0.000
H65.2 Chronic serous otitis media	0.728	0.272	0.000
H02.0 Entropion and trichiasis of eyelid	0.728	0.272	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.727	0.273	0.000
H04 Disorders of lachrymal system	0.727	0.273	0.000
J32.2 Chronic ethmoidal sinusitis	0.726	0.274	0.000
N64.8 Other specified disorders of breast	0.725	0.275	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.723	0.277	0.000
K42 Umbilical hernia	0.722	0.278	0.000
S42.1 Fracture of scapula	0.721	0.279	0.000
I21.9 Acute myocardial infarction, unspecified	0.720	0.280	0.000
H54.9 Unspecified visual impairment (binocular)	0.720	0.280	0.000
S02.2 Fracture of nasal bones	0.718	0.281	0.000
E55 Vitamin D deficiency	0.718	0.282	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
R36 Urethral discharge	0.717	0.283	0.000
H30-H36 Disorders of choroid and retina	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.717	0.283	0.000
E03.8 Other specified hypothyroidism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
T33-T35 Frostbite	0.716	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.283	0.000
J37 Chronic laryngitis and laryngotracheitis	0.715	0.285	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.715	0.285	0.000
E85 Amyloidosis	0.714	0.285	0.000
E84 Cystic fibrosis	0.714	0.285	0.000
E79 Disorders of purine and pyrimidine metabolism	0.714	0.285	0.000
E77 Disorders of glycoprotein metabolism	0.714	0.285	0.000
E76 Disorders of glycosaminoglycan metabolism	0.714	0.285	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.714	0.285	0.000
E74 Other disorders of carbohydrate metabolism	0.714	0.285	0.000
E73 Lactose intolerance	0.714	0.285	0.000
E72 Other disorders of amino-acid metabolism	0.714	0.285	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.714	0.285	0.000
E70 Disorders of aromatic amino-acid metabolism	0.714	0.285	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.714	0.285	0.000
F60-F69 Disorders of adult personality and behaviour	0.714	0.286	0.000
H73.8 Other specified disorders of tympanic membrane	0.714	0.286	0.000
E78.8 Other disorders of lipoprotein metabolism	0.713	0.286	0.000
E78.6 Lipoprotein deficiency	0.713	0.286	0.000
E78.3 Hyperchylomicronaemia	0.713	0.286	0.000
E78.1 Pure hyperglyceridaemia	0.713	0.286	0.000
K28 Gastrojejunal ulcer	0.713	0.287	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.713	0.287	0.000
K63.9 Disease of intestine, unspecified	0.712	0.288	0.000
J42 Unspecified chronic bronchitis	0.712	0.288	0.000
R25.3 Fasciculation	0.711	0.288	0.000
T43.2 Other and unspecified antidepressants	0.710	0.290	0.000
N40 Hyperplasia of prostate	0.710	0.290	0.000
J31.1 Chronic nasopharyngitis	0.709	0.291	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.709	0.291	0.000
K60.1 Chronic anal fissure	0.708	0.292	0.000
J21 Acute bronchiolitis	0.708	0.292	0.000
I27 Other pulmonary heart diseases	0.708	0.292	0.000
F31.9 Bipolar affective disorder, unspecified	0.706	0.294	0.000
H90-H95 Other disorders of ear	0.706	0.294	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.705	0.295	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.704	0.296	0.000
H70 Mastoiditis and related conditions	0.704	0.296	0.000
H68 Eustachian salpingitis and obstruction	0.704	0.296	0.000
H67 Otitis media in diseases classified elsewhere	0.704	0.296	0.000
H69 Other disorders of Eustachian tube	0.704	0.296	0.000
R09.3 Abnormal sputum	0.702	0.297	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.702	0.298	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.702	0.298	0.000
N20.9 Urinary calculus, unspecified	0.701	0.298	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.701	0.299	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.701	0.299	0.000
R09.1 Pleurisy	0.700	0.300	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.700	0.300	0.000
M77 Other enthesopathies	0.699	0.300	0.000
H18 Other disorders of cornea	0.699	0.301	0.000
I20 Angina pectoris	0.698	0.302	0.000
N50.1 Vascular disorders of male genital organs	0.698	0.302	0.000
K61.4 Intrasphincteric abscess	0.697	0.303	0.000
K61.2 Anorectal abscess	0.697	0.303	0.000
K61.1 Rectal abscess	0.697	0.303	0.000
E11 Non-insulin-dependent diabetes mellitus	0.697	0.303	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.696	0.304	0.000
K55 Vascular disorders of intestine	0.696	0.304	0.000
N64.4 Mastodynia	0.696	0.304	0.000
H10-H13 Disorders of conjunctiva	0.695	0.304	0.000
J32.3 Chronic sphenoidal sinusitis	0.694	0.306	0.000
J32.1 Chronic frontal sinusitis	0.694	0.306	0.000
T14 Injury of unspecified body region	0.694	0.306	0.000
J20 Acute bronchitis	0.694	0.306	0.000
M71 Other bursopathies	0.693	0.306	0.000
J46 Status asthmaticus	0.693	0.307	0.000
S43.0 Dislocation of shoulder joint	0.691	0.309	0.000
K60.5 Anorectal fistula	0.690	0.310	0.000
K60.4 Rectal fistula	0.690	0.310	0.000
K60.0 Acute anal fissure	0.690	0.310	0.000
E87.0 Hyperosmolality and hypernatraemia	0.689	0.311	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.689	0.311	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.689	0.311	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.689	0.311	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.689	0.311	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.689	0.311	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.689	0.311	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.689	0.311	0.000
T36 Poisoning by systemic antibiotics	0.689	0.311	0.000
I05 Rheumatic mitral valve diseases	0.688	0.311	0.000
Chapter XXII Codes for special purposes	0.687	0.313	0.000
K62.4 Stenosis of anus and rectum	0.687	0.313	0.000
F99-F99 Unspecified mental disorder	0.686	0.314	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.686	0.314	0.000
F70-F79 Mental retardation	0.686	0.314	0.000
H53.2 Diplopia	0.686	0.314	0.000
K63.3 Ulcer of intestine	0.685	0.315	0.000
S09.9 Unspecified injury of head	0.683	0.317	0.000
R26.3 Immobility	0.682	0.318	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.682	0.318	0.000
T68 Hypothermia	0.682	0.318	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.682	0.318	0.000
S70-S79 Injuries to the hip and thigh	0.681	0.318	0.000
J41 Simple and mucopurulent chronic bronchitis	0.681	0.319	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.681	0.319	0.000
S48 Traumatic amputation of shoulder and upper arm	0.681	0.319	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.681	0.319	0.000
S44 Injury of nerves at shoulder and upper arm level	0.681	0.319	0.000
S41 Open wound of shoulder and upper arm	0.681	0.319	0.000
S47 Crushing injury of shoulder and upper arm	0.681	0.319	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.681	0.319	0.000
E61 Deficiency of other nutrient elements	0.681	0.319	0.000
R27.0 Ataxia, unspecified	0.680	0.319	0.000
I60-I69 Cerebrovascular diseases	0.680	0.320	0.000
F30.0 Hypomania	0.680	0.320	0.000
K63.4 Enteroptosis	0.679	0.321	0.000
H02.4 Ptosis of eyelid	0.678	0.322	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.678	0.322	0.000
F38 Other mood [affective] disorders	0.678	0.322	0.000
F34 Persistent mood [affective] disorders	0.678	0.322	0.000
F39 Unspecified mood [affective] disorder	0.678	0.322	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.677	0.323	0.000
N99.5 Malfunction of external stoma of urinary tract	0.677	0.323	0.000
N99.2 Postprocedural adhesions of vagina	0.677	0.323	0.000
N99.1 Postprocedural urethral stricture	0.677	0.323	0.000
R82 Other abnormal findings in urine	0.677	0.323	0.000
N20.1 Calculus of ureter	0.675	0.325	0.000
S02.6 Fracture of mandible	0.674	0.326	0.000
S02.5 Fracture of tooth	0.674	0.326	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.674	0.326	0.000
S90-S99 Injuries to the ankle and foot	0.672	0.327	0.000
H60 Otitis externa	0.672	0.328	0.000
S06 Intracranial injury	0.672	0.328	0.000
K14 Diseases of tongue	0.672	0.328	0.000
F80-F89 Disorders of psychological development	0.672	0.328	0.000
G20-G26 Extrapyramidal and movement disorders	0.672	0.328	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.672	0.328	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.671	0.329	0.000
S02.1 Fracture of base of skull	0.670	0.330	0.000
M46 Other inflammatory spondylopathies	0.668	0.332	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.668	0.332	0.000
G90-G99 Other disorders of the nervous system	0.667	0.333	0.000
S02.4 Fracture of malar and maxillary bones	0.667	0.333	0.000
H61.0 Perichondritis of external ear	0.666	0.334	0.000
R04.2 Haemoptysis	0.666	0.334	0.000
N71 Inflammatory disease of uterus, except cervix	0.665	0.335	0.000
I95 Hypotension	0.664	0.336	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.664	0.336	0.000
S40.0 Contusion of shoulder and upper arm	0.663	0.337	0.000
R39.1 Other difficulties with micturition	0.663	0.337	0.000
H54.4 Blindness, one eye	0.662	0.338	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.662	0.338	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.661	0.339	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.660	0.340	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.660	0.340	0.000
H05 Disorders of orbit	0.660	0.340	0.000
H21 Other disorders of iris and ciliary body	0.660	0.340	0.000
F32 Depressive episode	0.660	0.340	0.000
K43 Ventral hernia	0.659	0.341	0.000
K22.1 Ulcer of oesophagus	0.658	0.342	0.000
C44 Other malignant neoplasms of skin	0.658	0.342	0.000
T93 Sequelae of injuries of lower limb	0.658	0.342	0.000
W00-W19 Falls	0.657	0.343	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.657	0.343	0.000
J34.3 Hypertrophy of nasal turbinates	0.657	0.343	0.000
H72.8 Other perforations of tympanic membrane	0.657	0.343	0.000
H02.3 Blepharochalasis	0.656	0.344	0.000
S08 Traumatic amputation of part of head	0.655	0.344	0.000
S07 Crushing injury of head	0.655	0.344	0.000
S05 Injury of eye and orbit	0.655	0.344	0.000
S04 Injury of cranial nerves	0.655	0.344	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.655	0.344	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.655	0.345	0.000
T78.2 Anaphylactic shock, unspecified	0.655	0.345	0.000
H72.2 Other marginal perforations of tympanic membrane	0.655	0.345	0.000
H72.1 Attic perforation of tympanic membrane	0.655	0.345	0.000
J86.9 Pyothorax without fistula	0.654	0.346	0.000
M47 Spondylosis	0.654	0.346	0.000
K59.3 Megacolon, not elsewhere classified	0.653	0.347	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.653	0.347	0.000
H66 Suppurative and unspecified otitis media	0.653	0.347	0.000
K12.0 Recurrent oral aphthae	0.653	0.347	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.653	0.347	0.000
R25.1 Tremor, unspecified	0.652	0.348	0.000
I25 Chronic ischaemic heart disease	0.650	0.350	0.000
R01 Cardiac murmurs and other cardiac sounds	0.650	0.350	0.000
F33.8 Other recurrent depressive disorders	0.650	0.350	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.650	0.350	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.650	0.350	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.650	0.350	0.000
I00-I02 Acute rheumatic fever	0.650	0.350	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.650	0.350	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.649	0.351	0.000
Q80-Q89 Other congenital malformations	0.648	0.352	0.000
N10 Acute tubulo-interstitial nephritis	0.647	0.352	0.000
S27 Injury of other and unspecified intrathoracic organs	0.647	0.352	0.000
E11.9 Without complications	0.647	0.353	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.647	0.353	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.645	0.355	0.000
M86-M90 Other osteopathies	0.645	0.355	0.000
R09.2 Respiratory arrest	0.644	0.355	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.644	0.356	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.644	0.356	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.642	0.358	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.642	0.358	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.642	0.358	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.642	0.358	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.642	0.358	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.642	0.358	0.000
K10 Other diseases of jaws	0.642	0.358	0.000
S01 Open wound of head	0.641	0.359	0.000
N50.8 Other specified disorders of male genital organs	0.641	0.359	0.000
H53.9 Visual disturbance, unspecified	0.641	0.359	0.000
H53.1 Subjective visual disturbances	0.641	0.359	0.000
R81 Glycosuria	0.641	0.359	0.000
Z93.0 Tracheostomy status	0.640	0.359	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.640	0.360	0.000
H20.8 Other iridocyclitis	0.639	0.361	0.000
K22.8 Other specified diseases of oesophagus	0.638	0.362	0.000
K59.8 Other specified functional intestinal disorders	0.638	0.362	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.638	0.362	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.638	0.362	0.000
I20.9 Angina pectoris, unspecified	0.637	0.363	0.000
K05 Gingivitis and periodontal diseases	0.637	0.363	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.637	0.363	0.000
J70 Respiratory conditions due to other external agents	0.636	0.363	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.636	0.363	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.636	0.363	0.000
J66 Airway disease due to specific organic dust	0.636	0.363	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.636	0.363	0.000
J62 Pneumoconiosis due to dust containing silica	0.636	0.363	0.000
J65 Pneumoconiosis associated with tuberculosis	0.636	0.363	0.000
J64 Unspecified pneumoconiosis	0.636	0.363	0.000
J60 Coalworker's pneumoconiosis	0.636	0.363	0.000
M65.3 Trigger finger	0.637	0.363	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.636	0.363	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.595	0.364	0.041
H49 Paralytic strabismus	0.636	0.364	0.000
T91 Sequelae of injuries of neck and trunk	0.635	0.365	0.000
W50-W64 Exposure to animate mechanical forces	0.633	0.367	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.633	0.367	0.000
M60-M63 Disorders of muscles	0.632	0.368	0.000
M00-M03 Infectious arthropathies	0.632	0.368	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.632	0.368	0.000
M91-M94 Chondropathies	0.631	0.369	0.000
H35 Other retinal disorders	0.631	0.369	0.000
K09 Cysts of oral region, not elsewhere classified	0.630	0.370	0.000
K65 Peritonitis	0.630	0.370	0.000
C82.0 Small cleaved cell, follicular	0.630	0.370	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.629	0.371	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations