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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1150689
log Bayes Factor = 81.376
Chromosome 6   position 28,165,099  (GRCh37) Explore rs1150689 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.995 0.005 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.995 0.005 0.000
E05.9 Thyrotoxicosis, unspecified
0.995 0.005 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.994 0.006 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.008 0.992
E16 Other disorders of pancreatic internal secretion
0.992 0.008 0.000
E16.2 Hypoglycaemia, unspecified
0.989 0.011 0.000
E14 Unspecified diabetes mellitus
0.980 0.020 0.000
E10.3 With ophthalmic complications
0.977 0.023 0.000
K40 Inguinal hernia
0.000 0.024 0.976
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.027 0.973
N40 Hyperplasia of prostate
0.000 0.061 0.939
E10.1 With ketoacidosis
0.933 0.067 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.931 0.069 0.000
E14.9 Without complications
0.919 0.081 0.000
E20-E35 Disorders of other endocrine glands
0.915 0.085 0.000
E10.2 With renal complications
0.898 0.102 0.000
E27 Other disorders of adrenal gland
0.867 0.133 0.000
E10.6 With other specified complications
0.865 0.135 0.000
E23 Hypofunction and other disorders of pituitary gland
0.861 0.139 0.000
E27.1 Primary adrenocortical insufficiency
0.839 0.161 0.000
E11 Non-insulin-dependent diabetes mellitus
0.836 0.164 0.000
K90 Intestinal malabsorption
0.829 0.170 0.002
E11.5 With peripheral circulatory complications
0.826 0.174 0.000
E23.2 Diabetes insipidus
0.816 0.184 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.814 0.186 0.000
E14.4 With neurological complications
0.803 0.197 0.000
E14.3 With ophthalmic complications
0.799 0.201 0.000
E07 Other disorders of thyroid
0.783 0.217 0.000
E10.7 With multiple complications
0.778 0.222 0.000
E10.5 With peripheral circulatory complications
0.776 0.224 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.764 0.235 0.000
E10.0 With coma
0.763 0.237 0.000
E14.6 With other specified complications
0.759 0.241 0.000
E14.1 With ketoacidosis
0.758 0.242 0.000
E14.2 Withrenal complications
0.749 0.251 0.000
E20 Hypoparathyroidism
0.734 0.265 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.723 0.277 0.000
E14.5 With peripheral circulatory complications
0.719 0.281 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.713 0.286 0.000
E00 Congenital iodine-deficiency syndrome
0.713 0.286 0.000
E05.5 Thyroid crisis or storm
0.713 0.286 0.000
E05.4 Thyrotoxicosis factitia
0.713 0.286 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.713 0.286 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.713 0.286 0.000
E15 Nondiabetic hypoglycaemic coma
0.713 0.287 0.000
E03 Other hypothyroidism
0.712 0.288 0.000
E31 Polyglandular dysfunction
0.711 0.289 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.711 0.289 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.711 0.289 0.000
E16.4 Abnormal secretion of gastrin
0.711 0.289 0.000
E16.3 Increased secretion of glucagon
0.711 0.289 0.000
E11.3 With ophthalmic complications
0.708 0.292 0.000
E23.0 Hypopituitarism
0.708 0.292 0.000
E10.4 With neurological complications
0.708 0.292 0.000
E14.7 With multiple complications
0.702 0.298 0.000
E14.0 With coma
0.702 0.298 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.300 0.700
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.300 0.700
E24 Cushing's syndrome
0.693 0.307 0.000
N40-N51 Diseases of male genital organs
0.000 0.310 0.690
E16.1 Other hypoglycaemia
0.688 0.312 0.000
N42 Other disorders of prostate
0.000 0.324 0.676
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.325 0.675
K90.9 Intestinal malabsorption, unspecified
0.674 0.325 0.001
E27.2 Addisonian crisis
0.668 0.332 0.000
E14.8 With unspecified complications
0.660 0.340 0.000
E25 Adrenogenital disorders
0.658 0.342 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.656 0.344 0.000
E32 Diseases of thymus
0.656 0.344 0.000
E30 Disorders of puberty, not elsewhere classified
0.656 0.344 0.000
N42.8 Other specified disorders of prostate
0.000 0.346 0.654
E11.6 With other specified complications
0.653 0.347 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.647 0.353 0.000
E40-E46 Malnutrition
0.641 0.359 0.000
E07.8 Other specified disorders of thyroid
0.630 0.370 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.624 0.376 0.000
N41 Inflammatory diseases of prostate
0.000 0.377 0.623
E27.5 Adrenomedullary hyperfunction
0.622 0.378 0.000
E27.0 Other adrenocortical overactivity
0.622 0.378 0.000
E28 Ovarian dysfunction
0.621 0.379 0.000
E05.8 Other thyrotoxicosis
0.621 0.379 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.618 0.382 0.000
E23.1 Drug-induced hypopituitarism
0.618 0.382 0.000
K90.8 Other intestinal malabsorption
0.613 0.385 0.001
E20.9 Hypoparathyroidism, unspecified
0.605 0.395 0.000
E10.8 With unspecified complications
0.603 0.397 0.000
E50-E64 Other nutritional deficiencies
0.601 0.399 0.000
E11.7 With multiple complications
0.599 0.401 0.000
N45 Orchitis and epididymitis
0.000 0.401 0.599
E23.6 Other disorders of pituitary gland
0.597 0.403 0.000
E06 Thyroiditis
0.597 0.403 0.000
E11.0 With coma
0.596 0.404 0.000
K90.3 Pancreatic steatorrhoea
0.594 0.405 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.594 0.405 0.001
K90.1 Tropical sprue
0.594 0.405 0.001
E27.9 Disorder of adrenal gland, unspecified
0.588 0.412 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.413 0.587
N46 Male infertility
0.000 0.423 0.577
N41.0 Acute prostatitis
0.000 0.434 0.566
E31.0 Autoimmune polyglandular failure
0.565 0.435 0.000
E07.9 Disorder of thyroid, unspecified
0.563 0.437 0.000
E24.2 Drug-induced Cushing's syndrome
0.562 0.438 0.000
E07.1 Dyshormogenetic goitre
0.562 0.438 0.000
E07.0 Hypersecretion of calcitonin
0.562 0.438 0.000
E23.7 Disorder of pituitary gland, unspecified
0.558 0.442 0.000
E29 Testicular dysfunction
0.558 0.442 0.000
N42.0 Calculus of prostate
0.000 0.444 0.556
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.445 0.555
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.450 0.550
E13 Other specified diabetes mellitus
0.548 0.451 0.000
E03.9 Hypothyroidism, unspecified
0.546 0.454 0.000
E24.0 Pituitary-dependent Cushing's disease
0.544 0.456 0.000
N44 Torsion of testis
0.000 0.456 0.544
E26 Hyperaldosteronism
0.526 0.473 0.000
E20.8 Other hypoparathyroidism
0.527 0.473 0.000
E20.1 Pseudohypoparathyroidism
0.527 0.473 0.000
E20.0 Idiopathic hypoparathyroidism
0.527 0.473 0.000
E34 Other endocrine disorders
0.517 0.483 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.516 0.484 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.512 0.488 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.512 0.488 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.512 0.488 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.512 0.488 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.512 0.488 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.512 0.488 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.512 0.488 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.512 0.488 0.000
E03.5 Myxoedema coma
0.510 0.489 0.000
E03.4 Atrophy of thyroid (acquired)
0.510 0.489 0.000
E03.3 Postinfectious hypothyroidism
0.510 0.489 0.000
E03.1 Congenital hypothyroidism without goitre
0.510 0.489 0.000
E31.9 Polyglandular dysfunction, unspecified
0.510 0.490 0.000
E31.8 Other polyglandular dysfunction
0.510 0.490 0.000
E31.1 Polyglandular hyperfunction
0.510 0.490 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.492 0.508
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.504 0.496 0.000
E11.1 With ketoacidosis
0.499 0.501 0.000
E24.8 Other Cushing's syndrome
0.497 0.503 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.497 0.503 0.000
E24.3 Ectopic ACTH syndrome
0.497 0.503 0.000
E24.1 Nelson's syndrome
0.497 0.503 0.000
E11.8 With unspecified complications
0.495 0.505 0.000
N42.3 Dysplasia of prostate
0.000 0.515 0.485
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.474 0.526 0.000
E25.9 Adrenogenital disorder, unspecified
0.472 0.528 0.000
E25.8 Other adrenogenital disorders
0.472 0.528 0.000
E28.3 Primary ovarian failure
0.471 0.529 0.000
E30.9 Disorder of puberty, unspecified
0.471 0.529 0.000
E30.8 Other disorders of puberty
0.471 0.529 0.000
E30.1 Precocious puberty
0.471 0.529 0.000
E30.0 Delayed puberty
0.471 0.529 0.000
E32.9 Disease of thymus, unspecified
0.471 0.529 0.000
E32.8 Other diseases of thymus
0.471 0.529 0.000
E32.1 Abscess of thymus
0.471 0.529 0.000
E32.0 Persistent hyperplasia of thymus
0.471 0.529 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.471 0.529 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.471 0.529 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.471 0.529 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.533 0.467
E03.8 Other specified hypothyroidism
0.466 0.534 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.460 0.540 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.460 0.540 0.000
E45 Retarded development following protein-energy malnutrition
0.460 0.540 0.000
E43 Unspecified severe protein-energy malnutrition
0.460 0.540 0.000
E42 Marasmic kwashiorkor
0.460 0.540 0.000
E41 Nutritional marasmus
0.460 0.540 0.000
E40 Kwashiorkor
0.460 0.540 0.000
E61 Deficiency of other nutrient elements
0.457 0.543 0.000
N42.2 Atrophy of prostate
0.000 0.546 0.454
E22 Hyperfunction of pituitary gland
0.452 0.548 0.000
N41.3 Prostatocystitis
0.000 0.553 0.447
N41.2 Abscess of prostate
0.000 0.553 0.447
E28.9 Ovarian dysfunction, unspecified
0.445 0.554 0.000
E28.8 Other ovarian dysfunction
0.445 0.554 0.000
E28.1 Androgen excess
0.445 0.554 0.000
E28.0 Oestrogen excess
0.445 0.554 0.000
E06.9 Thyroiditis, unspecified
0.441 0.559 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.431 0.569 0.000
E63 Other nutritional deficiencies
0.431 0.569 0.000
E56 Other vitamin deficiencies
0.431 0.569 0.000
E50 Vitamin A deficiency
0.431 0.569 0.000
E60 Dietary zinc deficiency
0.431 0.569 0.000
E59 Dietary selenium deficiency
0.431 0.569 0.000
E54 Ascorbic acid deficiency
0.431 0.569 0.000
E52 Niacin deficiency [pellagra]
0.431 0.569 0.000
E06.5 Other chronic thyroiditis
0.431 0.569 0.000
E06.4 Drug-induced thyroiditis
0.428 0.572 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.428 0.572 0.000
E06.1 Subacute thyroiditis
0.428 0.572 0.000
E06.0 Acute thyroiditis
0.428 0.572 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.573 0.427
E51 Thiamine deficiency
0.426 0.573 0.000
E53 Deficiency of other B group vitamins
0.423 0.576 0.000
E58 Dietary calcium deficiency
0.416 0.584 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.415 0.585 0.000
K40-K46 Hernia
0.000 0.588 0.412
N42.9 Disorder of prostate, unspecified
0.000 0.598 0.402
E29.9 Testicular dysfunction, unspecified
0.400 0.600 0.000
E29.8 Other testicular dysfunction
0.400 0.600 0.000
E29.0 Testicular hyperfunction
0.400 0.600 0.000
E13.8 With unspecified complications
0.393 0.607 0.000
E13.7 With multiple complications
0.393 0.607 0.000
E13.6 With other specified complications
0.393 0.607 0.000
E13.5 With peripheral circulatory complications
0.393 0.607 0.000
E13.4 With neurological complications
0.393 0.607 0.000
E13.2 With renal complications
0.393 0.607 0.000
E13.1 With ketoacidosis
0.393 0.607 0.000
E13.0 With coma
0.393 0.607 0.000
K41 Femoral hernia
0.000 0.607 0.393
E13.3 With ophthalmic complications
0.390 0.610 0.000
E46 Unspecified protein-energy malnutrition
0.385 0.615 0.000
E61.1 Iron deficiency
0.382 0.618 0.000
E24.9 Cushing's syndrome, unspecified
0.379 0.620 0.000
E26.9 Hyperaldosteronism, unspecified
0.378 0.622 0.000
E26.8 Other hyperaldosteronism
0.378 0.622 0.000
E26.1 Secondary hyperaldosteronism
0.378 0.622 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.624 0.375
E34.8 Other specified endocrine disorders
0.374 0.626 0.000
E28.2 Polycystic ovarian syndrome
0.374 0.626 0.000
E34.5 Androgen resistance syndrome
0.370 0.629 0.000
E34.4 Constitutional tall stature
0.370 0.629 0.000
E34.3 Short stature, not elsewhere classified
0.370 0.629 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.370 0.629 0.000
E34.1 Other hypersecretion of intestinal hormones
0.370 0.629 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.630 0.370
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.646 0.354
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.647 0.353
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.665 0.335
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.665 0.335
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.665 0.335
N43 Hydrocele and spermatocele
0.000 0.670 0.330
E44.1 Mild protein-energy malnutrition
0.330 0.670 0.000
E44.0 Moderate protein-energy malnutrition
0.330 0.670 0.000
E61.9 Deficiency of nutrient element, unspecified
0.328 0.672 0.000
E61.8 Deficiency of other specified nutrient elements
0.328 0.672 0.000
E61.7 Deficiency of multiple nutrient elements
0.328 0.672 0.000
E61.6 Vanadium deficiency
0.328 0.672 0.000
E61.5 Molybdenum deficiency
0.328 0.672 0.000
E61.4 Chromium deficiency
0.328 0.672 0.000
E61.3 Manganese deficiency
0.328 0.672 0.000
E61.0 Copper deficiency
0.328 0.672 0.000
E34.0 Carcinoid syndrome
0.326 0.674 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.324 0.676 0.000
E22.8 Other hyperfunction of pituitary gland
0.324 0.676 0.000
E53.8 Deficiency of other specified B group vitamins
0.320 0.680 0.000
E21.4 Other specified disorders of parathyroid gland
0.318 0.682 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.315 0.685 0.000
E55 Vitamin D deficiency
0.312 0.688 0.000
E11.2 With renal complications
0.310 0.690 0.000
E50.9 Vitamin A deficiency, unspecified
0.309 0.691 0.000
E50.8 Other manifestations of vitamin A deficiency
0.309 0.691 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.309 0.691 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.309 0.691 0.000
E50.5 Vitamin A deficiency with night blindness
0.309 0.691 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.309 0.691 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.309 0.691 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.309 0.691 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.309 0.691 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.309 0.691 0.000
E56.9 Vitamin deficiency, unspecified
0.309 0.691 0.000
E56.8 Deficiency of other vitamins
0.309 0.691 0.000
E56.1 Deficiency of vitamin K
0.309 0.691 0.000
E56.0 Deficiency of vitamin E
0.309 0.691 0.000
E63.9 Nutritional deficiency, unspecified
0.309 0.691 0.000
E63.8 Other specified nutritional deficiencies
0.309 0.691 0.000
E63.1 Imbalance of constituents of food intake
0.309 0.691 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.309 0.691 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.309 0.691 0.000
E64.8 Sequelae of other nutritional deficiencies
0.309 0.691 0.000
E64.3 Sequelae of rickets
0.309 0.691 0.000
E64.2 Sequelae of vitamin C deficiency
0.309 0.691 0.000
E64.1 Sequelae of vitamin A deficiency
0.309 0.691 0.000
E64.0 Sequelae of protein-energy malnutrition
0.309 0.691 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.693 0.307
E51.9 Thiamine deficiency, unspecified
0.306 0.694 0.000
E51.8 Other manifestations of thiamine deficiency
0.306 0.694 0.000
E51.1 Beriberi
0.306 0.694 0.000
E22.1 Hyperprolactinaemia
0.305 0.694 0.000
E53.1 Pyridoxine deficiency
0.304 0.696 0.000
E53.0 Riboflavin deficiency
0.304 0.696 0.000
K46 Unspecified abdominal hernia
0.000 0.697 0.303
E29.1 Testicular hypofunction
0.301 0.698 0.000
E51.2 Wernicke's encephalopathy
0.301 0.699 0.000
K44 Diaphragmatic hernia
0.000 0.699 0.301
E21.5 Disorder of parathyroid gland, unspecified
0.297 0.703 0.000
E21.2 Other hyperparathyroidism
0.294 0.706 0.000
E34.9 Endocrine disorder, unspecified
0.292 0.708 0.000
E06.3 Autoimmune thyroiditis
0.283 0.717 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.718 0.282
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.718 0.282
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.718 0.282
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.718 0.282
E61.2 Magnesium deficiency
0.280 0.720 0.000
N41.1 Chronic prostatitis
0.000 0.723 0.277
E53.9 Vitamin B deficiency, unspecified
0.276 0.724 0.000
E65-E68 Obesity and other hyperalimentation
0.270 0.729 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.735 0.265
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.735 0.265
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.735 0.265
E21.3 Hyperparathyroidism, unspecified
0.253 0.747 0.000
E11.9 Without complications
0.252 0.748 0.000
E11.4 With neurological complications
0.249 0.751 0.000
E26.0 Primary hyperaldosteronism
0.248 0.752 0.001
N50 Other disorders of male genital organs
0.000 0.752 0.248
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.242 0.758 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.759 0.241
E27.8 Other specified disorders of adrenal gland
0.239 0.759 0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.760 0.240
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.762 0.238
N43.2 Other hydrocele
0.000 0.763 0.237
N43.1 Infected hydrocele
0.000 0.763 0.237
N43.0 Encysted hydrocele
0.000 0.763 0.237
E13.9 Without complications
0.231 0.769 0.000
N48 Other disorders of penis
0.000 0.771 0.229
E55.0 Rickets, active
0.224 0.776 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.780 0.220
K43 Ventral hernia
0.000 0.780 0.220
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.782 0.218
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.783 0.217
N48.4 Impotence of organic origin
0.000 0.783 0.217
K44.1 Diaphragmatic hernia with gangrene
0.000 0.784 0.216
N50.9 Disorder of male genital organs, unspecified
0.000 0.792 0.208
E21.0 Primary hyperparathyroidism
0.207 0.793 0.000
N43.4 Spermatocele
0.000 0.794 0.206
N50.0 Atrophy of testis
0.000 0.804 0.196
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.805 0.195
E67 Other hyperalimentation
0.194 0.806 0.000
E68 Sequelae of hyperalimentation
0.194 0.806 0.000
N48.1 Balanoposthitis
0.000 0.808 0.192
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.810 0.190
N49.2 Inflammatory disorders of scrotum
0.000 0.813 0.187
E22.0 Acromegaly and pituitary gigantism
0.181 0.818 0.001
E04 Other non-toxic goitre
0.178 0.822 0.000
K45 Other abdominal hernia
0.001 0.822 0.177
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.842 0.158
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.842 0.158
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.842 0.158
K43.4 Parastomal hernia with gangrene
0.000 0.842 0.158
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.842 0.158
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.842 0.158
K43.1 Ventral hernia with gangrene
0.000 0.842 0.158
N48.2 Other inflammatory disorders of penis
0.000 0.843 0.157
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.849 0.151
N48.5 Ulcer of penis
0.000 0.854 0.146
N48.3 Priapism
0.000 0.858 0.142
K42 Umbilical hernia
0.000 0.860 0.140
E67.8 Other specified hyperalimentation
0.139 0.860 0.000
E67.3 Hypervitaminosis D
0.139 0.860 0.000
E67.2 Megavitamin-B6 syndrome
0.139 0.860 0.000
E67.1 Hypercarotenaemia
0.139 0.860 0.000
E67.0 Hypervitaminosis A
0.139 0.860 0.000
N43.3 Hydrocele, unspecified
0.000 0.864 0.136
N48.0 Leukoplakia of penis
0.000 0.867 0.133
E04.8 Other specified non-toxic goitre
0.127 0.872 0.000
K45.1 Other specified abdominal hernia with gangrene
0.001 0.872 0.127
K90-K93 Other diseases of the digestive system
0.047 0.878 0.075
E65 Localised adiposity
0.109 0.890 0.001
K92.0 Haematemesis
0.000 0.894 0.106
E55.9 Vitamin D deficiency, unspecified
0.105 0.895 0.000
E04.0 Non-toxic diffuse goitre
0.101 0.898 0.000
K42.1 Umbilical hernia with gangrene
0.000 0.899 0.100
E04.1 Non-toxic single thyroid nodule
0.100 0.900 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.905 0.095
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.908 0.092
K92 Other diseases of digestive system
0.001 0.908 0.091
N48.6 Balanitis xerotica obliterans
0.000 0.908 0.092
E04.9 Non-toxic goitre, unspecified
0.091 0.909 0.000
E83 Disorders of mineral metabolism
0.002 0.911 0.087
K93 Disorders of other digestive organs in diseases classified elsewhere
0.034 0.912 0.054
K92.9 Disease of digestive system, unspecified
0.000 0.916 0.083
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.921 0.078
K50 Crohn's disease [regional enteritis]
0.000 0.925 0.075
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.926 0.074
Chapter XI Diseases of the digestive system
0.000 0.928 0.072
K50-K52 Noninfective enteritis and colitis
0.000 0.928 0.072
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.929 0.071
K50.1 Crohn's disease of large intestine
0.000 0.930 0.070
K50.8 Other Crohn's disease
0.000 0.931 0.069
K50.0 Crohn's disease of small intestine
0.000 0.936 0.064
E83.9 Disorder of mineral metabolism, unspecified
0.002 0.936 0.062
E83.8 Other disorders of mineral metabolism
0.002 0.936 0.062
E83.2 Disorders of zinc metabolism
0.002 0.936 0.062
E83.0 Disorders of copper metabolism
0.002 0.936 0.062
N48.9 Disorder of penis, unspecified
0.001 0.937 0.062
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.025 0.937 0.039
K93.1 Megacolon in Chagas' disease
0.025 0.937 0.039
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.025 0.937 0.039
E83.3 Disorders of phosphorus metabolism
0.001 0.937 0.062
K50.9 Crohn's disease, unspecified
0.000 0.937 0.063
K51 Ulcerative colitis
0.000 0.939 0.061
K92.8 Other specified diseases of digestive system
0.001 0.940 0.060
K51.9 Ulcerative colitis, unspecified
0.000 0.942 0.058
K51.2 Ulcerative (chronic) proctitis
0.000 0.945 0.055
K35-K38 Diseases of appendix
0.000 0.945 0.055
K75.4 Autoimmune hepatitis
0.052 0.948 0.000
K37 Unspecified appendicitis
0.000 0.952 0.048
R47.0 Dysphasia and aphasia
0.048 0.952 0.000
N48.8 Other specified disorders of penis
0.000 0.953 0.046
K75 Other inflammatory liver diseases
0.046 0.953 0.000
K75.8 Other specified inflammatory liver diseases
0.044 0.956 0.000
K75.9 Inflammatory liver disease, unspecified
0.044 0.956 0.000
K38 Other diseases of appendix
0.000 0.956 0.044
I83 Varicose veins of lower extremities
0.000 0.956 0.044
K36 Other appendicitis
0.000 0.957 0.042
K51.4 Pseudopolyposis of colon
0.000 0.958 0.042
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.959 0.041
N39.0 Urinary tract infection, site not specified
0.000 0.960 0.040
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.962 0.038
K51.5 Mucosal proctocolitis
0.000 0.962 0.038
K38.8 Other specified diseases of appendix
0.000 0.963 0.037
R47 Speech disturbances, not elsewhere classified
0.035 0.965 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.033 0.966 0.000
K75.2 Nonspecific reactive hepatitis
0.033 0.966 0.000
K75.1 Phlebitis of portal vein
0.033 0.966 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.004 0.966 0.030
R47.1 Dysarthria and anarthria
0.034 0.966 0.000
Z90.5 Acquired absence of kidney
0.000 0.966 0.034
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.967 0.033
K38.1 Appendicular concretions
0.000 0.967 0.033
N50.1 Vascular disorders of male genital organs
0.000 0.968 0.032
R30.0 Dysuria
0.000 0.968 0.032
E04.2 Non-toxic multinodular goitre
0.032 0.968 0.000
K38.3 Fistula of appendix
0.000 0.968 0.032
K38.2 Diverticulum of appendix
0.000 0.968 0.032
K38.0 Hyperplasia of appendix
0.000 0.968 0.032
K65-K67 Diseases of peritoneum
0.000 0.968 0.031
R30 Pain associated with micturition
0.000 0.969 0.031
R30-R39 Symptoms and signs involving the urinary system
0.000 0.969 0.031
K51.8 Other ulcerative colitis
0.000 0.970 0.030
K38.9 Disease of appendix, unspecified
0.000 0.970 0.029
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.971 0.029
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.972 0.028
E83.4 Disorders of magnesium metabolism
0.001 0.972 0.027
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.973 0.027
K91.5 Postcholecystectomy syndrome
0.002 0.973 0.025
K91.0 Vomiting following gastro-intestinal surgery
0.002 0.974 0.024
R30.1 Vesical tenesmus
0.000 0.975 0.025
M20.1 Hallux valgus (acquired)
0.000 0.975 0.025
K91.2 Postsurgical malabsorption, not elsewhere classified
0.003 0.975 0.022
N39 Other disorders of urinary system
0.000 0.976 0.024
N39.9 Disorder of urinary system, unspecified
0.000 0.976 0.024
T39.1 4-Aminophenol derivatives
0.000 0.977 0.023
E66 Obesity
0.023 0.977 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.977 0.023
K75.0 Abscess of liver
0.022 0.978 0.000
K91.1 Postgastric surgery syndromes
0.003 0.978 0.019
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.979 0.021
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.979 0.021
K92.1 Melaena
0.000 0.979 0.021
R36 Urethral discharge
0.000 0.979 0.020
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.980 0.020
N39.8 Other specified disorders of urinary system
0.000 0.980 0.020
R30.9 Painful micturition, unspecified
0.000 0.981 0.019
T39.0 Salicylates
0.000 0.981 0.019
K91.9 Postprocedural disorder of digestive system, unspecified
0.003 0.981 0.016
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.981 0.019
K66 Other disorders of peritoneum
0.000 0.981 0.019
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.001 0.981 0.018
K91.4 Colostomy and enterostomy malfunction
0.001 0.982 0.017
R34 Anuria and oliguria
0.000 0.982 0.018
N39.2 Orthostatic proteinuria, unspecified
0.000 0.982 0.018
M13.00 Polyarthritis, unspecified (Multiple sites)
0.017 0.983 0.000
E66.1 Drug-induced obesity
0.016 0.983 0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.983 0.016
K67.3 Tuberculous peritonitis
0.000 0.983 0.016
K67.2 Syphilitic peritonitis
0.000 0.983 0.016
K67.1 Gonococcal peritonitis
0.000 0.983 0.016
K67.0 Chlamydial peritonitis
0.000 0.983 0.016
N39.1 Persistent proteinuria, unspecified
0.000 0.984 0.016
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.984 0.016
T39.4 Antirheumatics, not elsewhere classified
0.000 0.984 0.015
T39.2 Pyrazolone derivatives
0.000 0.984 0.015
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.985 0.015
K66.1 Haemoperitoneum
0.000 0.985 0.015
K66.9 Disorder of peritoneum, unspecified
0.000 0.985 0.015
R47.8 Other and unspecified speech disturbances
0.015 0.985 0.000
N84.1 Polyp of cervix uteri
0.000 0.986 0.014
K91.3 Postoperative intestinal obstruction
0.002 0.986 0.012
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.986 0.014
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.986 0.014
E66.2 Extreme obesity with alveolar hypoventilation
0.013 0.987 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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