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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115291397
log Bayes Factor = 6.50118
Chromosome 2   position 61,060,043  (GRCh37) Explore rs115291397 on Ensembl!
Variant rs115291397 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.989 0.011 0.000
D22 Melanocytic naevi
0.987 0.013 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.976 0.024 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.973 0.027 0.000
Z03.8 Observation for other suspected diseases and conditions
0.963 0.037 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.958 0.042 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.951 0.049 0.000
Chapter I Certain infectious and parasitic diseases
0.946 0.054 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.945 0.055 0.000
J09-J18 Influenza and pneumonia
0.943 0.057 0.000
J90-J94 Other diseases of pleura
0.941 0.059 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.937 0.063 0.000
I30-I52 Other forms of heart disease
0.926 0.074 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.925 0.075 0.000
C44 Other malignant neoplasms of skin
0.921 0.079 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.920 0.080 0.000
D22.4 Melanocytic naevi of scalp and neck
0.914 0.086 0.000
Z51 Other medical care
0.913 0.087 0.000
I05-I09 Chronic rheumatic heart diseases
0.910 0.090 0.000
J30-J39 Other diseases of upper respiratory tract
0.908 0.092 0.000
I26 Pulmonary embolism
0.908 0.092 0.000
J18 Pneumonia, organism unspecified
0.907 0.093 0.000
Chapter XX External causes of morbidity and mortality
0.900 0.100 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.887 0.113 0.000
D18 Haemangioma and lymphangioma, any site
0.885 0.115 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.883 0.117 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.882 0.118 0.000
J95-J99 Other diseases of the respiratory system
0.881 0.119 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.878 0.122 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.876 0.124 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.872 0.128 0.000
J00-J06 Acute upper respiratory infections
0.865 0.135 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.863 0.137 0.000
I51 Complications and ill-defined descriptions of heart disease
0.861 0.139 0.000
L60-L75 Disorders of skin appendages
0.861 0.139 0.000
I08 Multiple valve diseases
0.854 0.146 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.851 0.148 0.000
D17 Benign lipomatous neoplasm
0.843 0.157 0.000
Z13 Special screening examination for other diseases and disorders
0.842 0.158 0.000
D22.5 Melanocytic naevi of trunk
0.842 0.158 0.000
I27 Other pulmonary heart diseases
0.839 0.161 0.000
I35 Nonrheumatic aortic valve disorders
0.838 0.162 0.000
J18.9 Pneumonia, unspecified
0.838 0.162 0.000
I49 Other cardiac arrhythmias
0.835 0.165 0.000
B95-B98 Bacterial, viral and other infectious agents
0.834 0.166 0.000
C44.4 Skin of scalp and neck
0.831 0.169 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.830 0.170 0.000
J92 Pleural plaque
0.827 0.173 0.000
A30-A49 Other bacterial diseases
0.827 0.173 0.000
Z01.8 Other specified special examinations
0.826 0.174 0.000
Z51.0 Radiotherapy session
0.826 0.174 0.000
C44.6 Skin of upper limb, including shoulder
0.824 0.176 0.000
J90 Pleural effusion, not elsewhere classified
0.820 0.180 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.813 0.187 0.000
I51.7 Cardiomegaly
0.808 0.192 0.000
M45-M49 Spondylopathies
0.808 0.192 0.000
D18.0 Haemangioma, any site
0.805 0.195 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.802 0.198 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.802 0.198 0.000
D27 Benign neoplasm of ovary
0.802 0.198 0.000
J34 Other disorders of nose and nasal sinuses
0.801 0.199 0.000
C34 Malignant neoplasm of bronchus and lung
0.799 0.201 0.000
I95 Hypotension
0.799 0.201 0.000
J98 Other respiratory disorders
0.797 0.203 0.000
J36 Peritonsillar abscess
0.797 0.203 0.000
Z01.6 Radiological examination, not elsewhere classified
0.797 0.203 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.797 0.203 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.791 0.209 0.000
I08.0 Disorders of both mitral and aortic valves
0.790 0.210 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.788 0.212 0.000
Z03.1 Observation for suspected malignant neoplasm
0.787 0.213 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.786 0.214 0.000
C44.2 Skin of ear and external auricular canal
0.786 0.214 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.786 0.214 0.000
Chapter VI Diseases of the nervous system
0.781 0.219 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.781 0.219 0.000
Z51.5 Palliative care
0.778 0.222 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.778 0.222 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.776 0.224 0.000
Z03.3 Observation for suspected nervous system disorder
0.776 0.224 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.772 0.228 0.000
Z42 Follow-up care involving plastic surgery
0.771 0.229 0.000
Z51.3 Blood transfusion without reported diagnosis
0.764 0.236 0.000
D23 Other benign neoplasms of skin
0.764 0.236 0.000
I34 Nonrheumatic mitral valve disorders
0.759 0.241 0.000
S80-S89 Injuries to the knee and lower leg
0.758 0.242 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.757 0.243 0.000
L82 Seborrhoeic keratosis
0.757 0.243 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.756 0.244 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.756 0.244 0.000
J18.0 Bronchopneumonia, unspecified
0.754 0.246 0.000
L81 Other disorders of pigmentation
0.753 0.247 0.000
J98.1 Pulmonary collapse
0.749 0.251 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.749 0.251 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.749 0.251 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.748 0.252 0.000
Z45 Adjustment and management of implanted device
0.748 0.252 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.746 0.254 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.745 0.255 0.000
Z12 Special screening examination for neoplasms
0.745 0.255 0.000
Z48 Other surgical follow-up care
0.745 0.255 0.000
J93 Pneumothorax
0.744 0.256 0.000
J18.1 Lobar pneumonia, unspecified
0.743 0.257 0.000
M20-M25 Other joint disorders
0.741 0.259 0.000
D36 Benign neoplasm of other and unspecified sites
0.736 0.264 0.000
I95.9 Hypotension, unspecified
0.735 0.265 0.000
S20-S29 Injuries to the thorax
0.734 0.266 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.733 0.267 0.000
M48 Other spondylopathies
0.732 0.268 0.000
Z03.4 Observation for suspected myocardial infarction
0.732 0.268 0.000
I27.2 Other secondary pulmonary hypertension
0.732 0.268 0.000
J00 Acute nasopharyngitis [common cold]
0.731 0.269 0.000
Z04 Examination and observation for other reasons
0.730 0.270 0.000
S00-S09 Injuries to the head
0.729 0.270 0.000
I51.8 Other ill-defined heart diseases
0.729 0.271 0.000
I49.9 Cardiac arrhythmia, unspecified
0.729 0.271 0.000
L08 Other local infections of skin and subcutaneous tissue
0.728 0.272 0.000
S70-S79 Injuries to the hip and thigh
0.727 0.273 0.000
Z49 Care involving dialysis
0.723 0.277 0.000
C50-C50 Malignant neoplasm of breast
0.722 0.278 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.722 0.278 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.721 0.279 0.000
L40-L45 Papulosquamous disorders
0.721 0.279 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.720 0.280 0.000
S90-S99 Injuries to the ankle and foot
0.720 0.280 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
C51-C58 Malignant neoplasms of female genital organs
0.716 0.284 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.716 0.284 0.000
C44.5 Skin of trunk
0.715 0.285 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.715 0.285 0.000
D31 Benign neoplasm of eye and adnexa
0.715 0.285 0.000
D30 Benign neoplasm of urinary organs
0.715 0.285 0.000
D29 Benign neoplasm of male genital organs
0.715 0.285 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.715 0.285 0.000
D26 Other benign neoplasms of uterus
0.715 0.285 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.715 0.285 0.000
D19 Benign neoplasm of mesothelial tissue
0.715 0.285 0.000
D16 Benign neoplasm of bone and articular cartilage
0.715 0.285 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.715 0.285 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.715 0.285 0.000
D11 Benign neoplasm of major salivary glands
0.715 0.285 0.000
D10 Benign neoplasm of mouth and pharynx
0.715 0.285 0.000
C34.9 Bronchus or lung, unspecified
0.715 0.285 0.000
D34 Benign neoplasm of thyroid gland
0.715 0.285 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.713 0.287 0.000
Y95 Nosocomial condition
0.712 0.288 0.000
J92.9 Pleural plaque without asbestos
0.711 0.289 0.000
L72.1 Trichilemmal cyst
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.710 0.290 0.000
C44.3 Skin of other and unspecified parts of face
0.710 0.290 0.000
Z43 Attention to artificial openings
0.710 0.290 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.709 0.291 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.708 0.292 0.000
A41 Other septicaemia
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
D22.9 Melanocytic naevi, unspecified
0.707 0.293 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.707 0.293 0.000
D22.0 Melanocytic naevi of lip
0.707 0.293 0.000
L05 Pilonidal cyst
0.707 0.293 0.000
J35 Chronic diseases of tonsils and adenoids
0.706 0.293 0.000
Z51.2 Other chemotherapy
0.706 0.294 0.000
E70-E90 Metabolic disorders
0.705 0.295 0.000
I35.0 Aortic (valve) stenosis
0.705 0.295 0.000
Z40 Prophylactic surgery
0.704 0.296 0.000
Z10 Routine general health check-up of defined subpopulation
0.704 0.296 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.704 0.296 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.704 0.296 0.000
J03 Acute tonsillitis
0.703 0.297 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.701 0.299 0.000
L10-L14 Bullous disorders
0.700 0.300 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.699 0.301 0.000
B25-B34 Other viral diseases
0.698 0.302 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.698 0.302 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.698 0.302 0.000
Z03.0 Observation for suspected tuberculosis
0.698 0.302 0.000
D25 Leiomyoma of uterus
0.696 0.304 0.000
L85 Other epidermal thickening
0.695 0.305 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.693 0.306 0.000
M86-M90 Other osteopathies
0.692 0.307 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.688 0.312 0.000
L89 Decubitus ulcer
0.687 0.313 0.000
I28 Other diseases of pulmonary vessels
0.687 0.313 0.000
C60-C63 Malignant neoplasms of male genital organs
0.687 0.313 0.000
E50-E64 Other nutritional deficiencies
0.686 0.314 0.000
O80-O84 Delivery
0.684 0.316 0.000
L71 Rosacea
0.683 0.317 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.683 0.317 0.000
J34.3 Hypertrophy of nasal turbinates
0.683 0.317 0.000
M40-M43 Deforming dorsopathies
0.682 0.318 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.682 0.318 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.681 0.319 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
B07 Viral warts
0.679 0.321 0.000
M48.0 Spinal stenosis
0.678 0.322 0.000
B99-B99 Other infectious diseases
0.678 0.322 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.678 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.678 0.322 0.000
B65-B83 Helminthiases
0.678 0.322 0.000
B50-B64 Protozoal diseases
0.678 0.322 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.322 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.678 0.322 0.000
A80-A89 Viral infections of the central nervous system
0.678 0.322 0.000
A75-A79 Rickettsioses
0.678 0.322 0.000
A70-A74 Other diseases caused by chlamydiae
0.678 0.322 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.678 0.322 0.000
A20-A28 Certain zoonotic bacterial diseases
0.678 0.322 0.000
A15-A19 Tuberculosis
0.678 0.322 0.000
Z54 Convalescence
0.678 0.322 0.000
Z52 Donors of organs and tissues
0.678 0.322 0.000
Z44 Fitting and adjustment of external prosthetic device
0.678 0.322 0.000
M50-M54 Other dorsopathies
0.677 0.323 0.000
J17 Pneumonia in diseases classified elsewhere
0.676 0.324 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.676 0.324 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.676 0.324 0.000
J12 Viral pneumonia, not elsewhere classified
0.676 0.324 0.000
J11 Influenza, virus not identified
0.676 0.324 0.000
J10 Influenza due to identified influenza virus
0.676 0.324 0.000
J14 Pneumonia due to Haemophilus influenzae
0.676 0.324 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.676 0.324 0.000
J09 Influenza due to certain identified influenza virus
0.676 0.324 0.000
W00-W19 Falls
0.676 0.324 0.000
T66-T78 Other and unspecified effects of external causes
0.676 0.324 0.000
D32 Benign neoplasm of meninges
0.676 0.324 0.000
M20 Acquired deformities of fingers and toes
0.676 0.324 0.000
J94 Other pleural conditions
0.675 0.325 0.000
J91 Pleural effusion in conditions classified elsewhere
0.675 0.325 0.000
I35.8 Other aortic valve disorders
0.674 0.326 0.000
Q80-Q89 Other congenital malformations
0.674 0.326 0.000
D70 Agranulocytosis
0.673 0.326 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.673 0.327 0.000
I49.8 Other specified cardiac arrhythmias
0.672 0.328 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.671 0.328 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.671 0.329 0.000
L50-L54 Urticaria and erythema
0.670 0.330 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.669 0.331 0.000
D35.2 Pituitary gland
0.666 0.334 0.000
I31 Other diseases of pericardium
0.666 0.334 0.000
I52 Other heart disorders in diseases classified elsewhere
0.664 0.336 0.000
I48 Atrial fibrillation and flutter
0.664 0.336 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.664 0.336 0.000
I41 Myocarditis in diseases classified elsewhere
0.664 0.336 0.000
I40 Acute myocarditis
0.664 0.336 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.664 0.336 0.000
I37 Pulmonary valve disorders
0.664 0.336 0.000
I36 Nonrheumatic tricuspid valve disorders
0.664 0.336 0.000
I33 Acute and subacute endocarditis
0.664 0.336 0.000
I32 Pericarditis in diseases classified elsewhere
0.664 0.336 0.000
I30 Acute pericarditis
0.664 0.336 0.000
T33-T35 Frostbite
0.663 0.336 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.663 0.336 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.663 0.336 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.336 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.663 0.336 0.000
T00-T07 Injuries involving multiple body regions
0.663 0.336 0.000
S10-S19 Injuries to the neck
0.663 0.336 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.663 0.336 0.000
O60-O75 Complications of labour and delivery
0.663 0.336 0.000
J92.0 Pleural plaque with presence of asbestos
0.663 0.337 0.000
M65-M68 Disorders of synovium and tendon
0.663 0.337 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.663 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
L81.4 Other melanin hyperpigmentation
0.661 0.339 0.000
C01 Malignant neoplasm of base of tongue
0.661 0.339 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.660 0.340 0.000
C44.8 Overlapping lesion of skin
0.660 0.340 0.000
C44.0 Skin of lip
0.660 0.340 0.000
C44.7 Skin of lower limb, including hip
0.660 0.340 0.000
X60-X84 Intentional self-harm
0.660 0.340 0.000
Z01.9 Special examination, unspecified
0.659 0.340 0.000
Z01.7 Laboratory examination
0.659 0.340 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.659 0.340 0.000
Z01.4 Gynaecological examination (general)(routine)
0.659 0.340 0.000
Z01.3 Examination of blood pressure
0.659 0.340 0.000
Z01.2 Dental examination
0.659 0.340 0.000
Z01.1 Examination of ears and hearing
0.659 0.340 0.000
Z01.0 Examination of eyes and vision
0.659 0.340 0.000
A49 Bacterial infection of unspecified site
0.658 0.342 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.658 0.342 0.000
D35.1 Parathyroid gland
0.658 0.342 0.000
C34.0 Main bronchus
0.658 0.342 0.000
Q60-Q64 Congenital malformations of the urinary system
0.658 0.342 0.000
D12.8 Rectum
0.658 0.342 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.657 0.343 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.656 0.344 0.000
E86 Volume depletion
0.656 0.344 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.655 0.345 0.000
M80-M85 Disorders of bone density and structure
0.655 0.345 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.655 0.345 0.000
Z51.9 Medical care, unspecified
0.654 0.346 0.000
Z51.6 Desensitisation to allergens
0.654 0.346 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.654 0.346 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.654 0.346 0.000
I09 Other rheumatic heart diseases
0.653 0.347 0.000
I07 Rheumatic tricuspid valve diseases
0.653 0.347 0.000
I06 Rheumatic aortic valve diseases
0.653 0.347 0.000
I05 Rheumatic mitral valve diseases
0.653 0.347 0.000
J60-J70 Lung diseases due to external agents
0.652 0.347 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.652 0.348 0.000
J37 Chronic laryngitis and laryngotracheitis
0.651 0.349 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.651 0.349 0.000
J18.8 Other pneumonia, organism unspecified
0.650 0.350 0.000
J18.2 Hypostatic pneumonia, unspecified
0.650 0.350 0.000
I27.0 Primary pulmonary hypertension
0.650 0.350 0.000
I84 Haemorrhoids
0.649 0.351 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.648 0.352 0.000
G90-G99 Other disorders of the nervous system
0.648 0.352 0.000
I42 Cardiomyopathy
0.647 0.353 0.000
I49.4 Other and unspecified premature depolarisation
0.647 0.353 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.646 0.354 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.646 0.354 0.000
W20-W49 Exposure to inanimate mechanical forces
0.646 0.354 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.646 0.354 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.645 0.355 0.000
Y35-Y36 Legal intervention and operations of war
0.645 0.355 0.000
Y10-Y34 Event of undetermined intent
0.645 0.355 0.000
Y00-Y09 Assault
0.645 0.355 0.000
X85-X99 Assault
0.645 0.355 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.645 0.355 0.000
X50-X57 Overexertion, travel and privation
0.645 0.355 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.645 0.355 0.000
X30-X39 Exposure to forces of nature
0.645 0.355 0.000
X20-X29 Contact with venomous animals and plants
0.645 0.355 0.000
X10-X19 Contact with heat and hot substances
0.645 0.355 0.000
X00-X09 Exposure to smoke, fire and flames
0.645 0.355 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.645 0.355 0.000
W75-W84 Other accidental threats to breathing
0.645 0.355 0.000
W65-W74 Accidental drowning and submersion
0.645 0.355 0.000
W50-W64 Exposure to animate mechanical forces
0.645 0.355 0.000
V98-V99 Other and unspecified transport accidents
0.645 0.355 0.000
V95-V97 Air and space transport accidents
0.645 0.355 0.000
V90-V94 Water transport accidents
0.645 0.355 0.000
V80-V89 Other land transport accidents
0.645 0.355 0.000
V70-V79 Bus occupant injured in transport accident
0.645 0.355 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.645 0.355 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.645 0.355 0.000
V40-V49 Car occupant injured in transport accident
0.645 0.355 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.355 0.000
V01-V09 Pedestrian injured in transport accident
0.645 0.355 0.000
Chapter VIII Diseases of the ear and mastoid process
0.645 0.355 0.000
A41.9 Septicaemia, unspecified
0.644 0.356 0.000
D80-D89 Certain disorders involving the immune mechanism
0.644 0.356 0.000
C43 Malignant melanoma of skin
0.643 0.357 0.000
D00-D09 In situ neoplasms
0.642 0.358 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.641 0.359 0.000
M91-M94 Chondropathies
0.636 0.364 0.000
M60-M63 Disorders of muscles
0.636 0.364 0.000
M00-M03 Infectious arthropathies
0.636 0.364 0.000
D18.1 Lymphangioma, any site
0.635 0.365 0.000
B35-B49 Mycoses
0.633 0.367 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.633 0.367 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.633 0.367 0.000
C32 Malignant neoplasm of larynx
0.633 0.367 0.000
C31 Malignant neoplasm of accessory sinuses
0.633 0.367 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.633 0.367 0.000
C37 Malignant neoplasm of thymus
0.633 0.367 0.000
C33 Malignant neoplasm of trachea
0.633 0.367 0.000
Z13.1 Special screening examination for diabetes mellitus
0.633 0.367 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.632 0.368 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.632 0.368 0.000
L94 Other localised connective tissue disorders
0.632 0.368 0.000
L93 Lupus erythematosus
0.632 0.368 0.000
L87 Transepidermal elimination disorders
0.632 0.368 0.000
L88 Pyoderma gangrenosum
0.632 0.368 0.000
L86 Keratoderma in diseases classified elsewhere
0.632 0.368 0.000
L84 Corns and callosities
0.632 0.368 0.000
L83 Acanthosis nigricans
0.632 0.368 0.000
L80 Vitiligo
0.632 0.368 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.632 0.368 0.000
J96 Respiratory failure, not elsewhere classified
0.632 0.368 0.000
Y86 Sequelae of other accidents
0.630 0.370 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.630 0.370 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.630 0.370 0.000
I99 Other and unspecified disorders of circulatory system
0.630 0.370 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.630 0.370 0.000
S81 Open wound of lower leg
0.628 0.371 0.000
L04 Acute lymphadenitis
0.628 0.372 0.000
L01 Impetigo
0.628 0.372 0.000
L00 Staphylococcal scalded skin syndrome
0.628 0.372 0.000
E20-E35 Disorders of other endocrine glands
0.627 0.373 0.000
Z57 Occupational exposure to risk-factors
0.627 0.373 0.000
Z51.8 Other specified medical care
0.627 0.373 0.000
Z50 Care involving use of rehabilitation procedures
0.626 0.374 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.622 0.378 0.000
M47 Spondylosis
0.622 0.378 0.000
Z47 Other orthopaedic follow-up care
0.621 0.378 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.621 0.379 0.000
Y52 Agents primarily affecting the cardiovascular system
0.621 0.379 0.000
Z46 Fitting and adjustment of other devices
0.620 0.380 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.620 0.380 0.000
J04 Acute laryngitis and tracheitis
0.620 0.380 0.000
J01 Acute sinusitis
0.620 0.380 0.000
C79 Secondary malignant neoplasm of other sites
0.620 0.380 0.000
J39 Other diseases of upper respiratory tract
0.620 0.380 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.619 0.381 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.619 0.381 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.619 0.381 0.000
Q50-Q56 Congenital malformations of genital organs
0.619 0.381 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.619 0.381 0.000
Q35-Q37 Cleft lip and cleft palate
0.619 0.381 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.619 0.381 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.619 0.381 0.000
Q00-Q07 Congenital malformations of the nervous system
0.619 0.381 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.618 0.382 0.000
I47 Paroxysmal tachycardia
0.618 0.382 0.000
S32 Fracture of lumbar spine and pelvis
0.618 0.382 0.000
D24 Benign neoplasm of breast
0.618 0.382 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.617 0.382 0.000
I51.6 Cardiovascular disease, unspecified
0.617 0.382 0.000
I51.5 Myocardial degeneration
0.617 0.382 0.000
I51.4 Myocarditis, unspecified
0.617 0.382 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.617 0.382 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.617 0.382 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.617 0.382 0.000
I51.0 Cardiac septal defect, acquired
0.617 0.382 0.000
L75 Apocrine sweat disorders
0.617 0.383 0.000
L74 Eccrine sweat disorders
0.617 0.383 0.000
L73 Other follicular disorders
0.617 0.383 0.000
L70 Acne
0.617 0.383 0.000
L68 Hypertrichosis
0.617 0.383 0.000
L67 Hair colour and hair shaft abnormalities
0.617 0.383 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.617 0.383 0.000
L65 Other nonscarring hair loss
0.617 0.383 0.000
L64 Androgenic alopecia
0.617 0.383 0.000
L63 Alopecia areata
0.617 0.383 0.000
L62 Nail disorders in diseases classified elsewhere
0.617 0.383 0.000
J38.3 Other diseases of vocal cords
0.613 0.386 0.000
Z45.8 Adjustment and management of other implanted devices
0.613 0.387 0.000
O00-O08 Pregnancy with abortive outcome
0.612 0.388 0.000
I08.9 Multiple valve disease, unspecified
0.612 0.388 0.000
I08.8 Other multiple valve diseases
0.612 0.388 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.612 0.388 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.612 0.388 0.000
I34.0 Mitral (valve) insufficiency
0.611 0.388 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.611 0.389 0.000
D55-D59 Haemolytic anaemias
0.610 0.389 0.000
Z41 Procedures for purposes other than remedying health state
0.609 0.390 0.000
Z60 Problems related to social environment
0.609 0.391 0.000
V10-V19 Pedal cyclist injured in transport accident
0.609 0.391 0.000
D23.4 Skin of scalp and neck
0.608 0.392 0.000
J38.1 Polyp of vocal cord and larynx
0.607 0.393 0.000
E53 Deficiency of other B group vitamins
0.605 0.395 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.605 0.395 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.605 0.395 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.605 0.395 0.000
C80 Malignant neoplasm without specification of site
0.605 0.395 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.604 0.396 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.604 0.396 0.000
Z13.5 Special screening examination for eye and ear disorders
0.604 0.396 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.604 0.396 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.604 0.396 0.000
Z13.2 Special screening examination for nutritional disorders
0.604 0.396 0.000
Z45.1 Adjustment and management of infusion pump
0.604 0.396 0.000
J32 Chronic sinusitis
0.603 0.397 0.000
J93.9 Pneumothorax, unspecified
0.603 0.397 0.000
I27.9 Pulmonary heart disease, unspecified
0.601 0.398 0.000
I27.8 Other specified pulmonary heart diseases
0.601 0.398 0.000
I27.1 Kyphoscoliotic heart disease
0.601 0.398 0.000
I35.9 Aortic valve disorder, unspecified
0.601 0.399 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.600 0.400 0.000
I95.1 Orthostatic hypotension
0.600 0.400 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.600 0.400 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.600 0.400 0.000
S00 Superficial injury of head
0.600 0.400 0.000
M20.2 Hallux rigidus
0.600 0.400 0.000
I49.3 Ventricular premature depolarisation
0.599 0.401 0.000
I49.2 Junctional premature depolarisation
0.599 0.401 0.000
I49.1 Atrial premature depolarisation
0.599 0.401 0.000
I49.0 Ventricular fibrillation and flutter
0.599 0.401 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.598 0.402 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.597 0.403 0.000
M45 Ankylosing spondylitis
0.595 0.405 0.000
D35.9 Endocrine gland, unspecified
0.595 0.405 0.000
D35.8 Pluriglandular involvement
0.595 0.405 0.000
D35.7 Other specified endocrine glands
0.595 0.405 0.000
D35.6 Aortic body and other paraganglia
0.595 0.405 0.000
D35.5 Carotid body
0.595 0.405 0.000
D35.4 Pineal gland
0.595 0.405 0.000
D35.3 Craniopharyngeal duct
0.595 0.405 0.000
D35.0 Adrenal gland
0.595 0.405 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.594 0.405 0.000
O72 Postpartum haemorrhage
0.594 0.406 0.000
I35.1 Aortic (valve) insufficiency
0.593 0.407 0.000
A48 Other bacterial diseases, not elsewhere classified
0.593 0.407 0.000
A44 Bartonellosis
0.593 0.407 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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